The present invention relates to digital modulation and demodulation of wireless communications, more particularly to a differential chaotic shift keying modulation and demodulation device based on the code subscript modulation. The modulation and demodulation device is provided with a modulator and a demodulator, wherein the modulator is provided with a chaotic carrier generator G; a delay unit D1; a multiplier a; a multiplier b; a bit-to-symbol converter f; a bit-to-symbol converter g; a Walsh code selector S; a square-wave generator e and a modulator transfer switch Q1; and the demodulator includes a receiver R; a delay unit D2; M square-wave generators S<1>, S<2>, ..., S<M>; M first-path multipliers M<1, 1>, M<1, 2>, ..., M<1, M>; M second-path multipliers M<2, 1>, M<2, 2>, ..., M<2, M>; M accumulators Ac<1>, Ac<2>, ..., Ac<M>; M absolute value pickers Ab<1>, Ab<2>, ..., Ab<M>; a comparator C; a demodulator transfer switch Q2; a resolver h and a symbol-to-bit converter k.