41331results about "Mixer accessories" patented technology

A powered surgical tool with a housing that contains a power generating unit such as a motor. A control module is disposed in a shell that is mounted in the housing. The control module contains a control circuit for regulating the actuation of the power generating unit. The power generating unit emits a signal representative of the operating state of the unit that is transmitted through the structural material forming the shell. Also internal to the control module shell is a sensor that monitors the signal emitted by the power generating unit. This signal output by the sensor is applied to the control circuit. The control circuit, based on the sensor signal regulates actuation of the power generating unit. Wherein the power generating unit is a motor, the signal emitted is the magnetic field that varies with rotor position. The sensor monitors the strength of this field.

This invention relates to a mixing and delivery device suitable for delivering injectable biomaterials, and to preferred bone cement formulations.

Methods are provided for forming a dispersion of substantially uniform droplets. An internal phase that includes a plurality of particles suspended in a first fluid is provided and an external phase including a second fluid is provided. The internal phase is vibrated and the internal phase is applied to the external phase. Either the internal phase or a combination of the internal and external phases form a series of droplets or complex droplets of substantially uniform size.

An apparatus is provided for manipulating droplets. The apparatus is a single-sided electrode design in which all conductive elements are contained on one surface on which droplets are manipulated. An additional surface can be provided parallel with the first surface for the purpose of containing the droplets to be manipulated. Droplets are manipulated by performing electrowetting-based techniques in which electrodes contained on or embedded in the first surface are sequentially energized and de-energized in a controlled manner. The apparatus enables a number of droplet manipulation processes, including merging and mixing two droplets together, splitting a droplet into two or more droplets, sampling a continuous liquid flow by forming from the flow individually controllable droplets, and iterative binary or digital mixing of droplets to obtain a desired mixing ratio.

The present invention provides microfluidic devices and methods using the same in various types of thermal cycling reactions. Certaom devices include a rotary microfluidic channel and a plurality of temperature regions at different locations along the rotary microfluidic channel at which temperature is regulated. Solution can be repeatedly passed through the temperature regions such that the solution is exposed to different temperatures. Other microfluidic devices include an array of reaction chambers formed by intersecting vertical and horizontal flow channels, with the ability to regulate temperature at the reaction chambers. The microfluidic devices can be used to conduct a number of different analyses, including various primer extension reactions and nucleic acid amplification reactions.

The invention relates to a microfabricated device for the rapid detection of DNA, proteins or other molecules associated with a particular disease. The devices and methods of the invention can be used for the simultaneous diagnosis of multiple diseases by detecting molecules (e.g. amounts of molecules), such as polynucleotides (e.g., DNA) or proteins (e.g., antibodies), by measuring the signal of a detectable reporter associated with hybridized polynucleotides or antigen / antibody complex. In the microfabricated device according to the invention, detection of the presence of molecules (i.e., polynucleotides, proteins, or antigen / antibody complexes) are correlated to a hybridization signal from an optically-detectable (e.g. fluorescent) reporter associated with the bound molecules. These hybridization signals can be detected by any suitable means, for example optical, and can be stored for example in a computer as a representation of the presence of a particular gene. Hybridization probes can be immobilized on a substrate that forms part of or is exposed to a channel or channels of the device that form a closed loop, for circulation of sample to actively contact complementary probes. Universal chips according to the invention can be fabricated not only with DNA but also with other molecules such as RNA, proteins, peptide nucleic acid (PNA) and polyamide molecules.

A method of treating a vertebra, comprising: (a) accessing an interior of a vertebra; and (b) introducing a sufficient amount of artificial biocompatible material which does not set to a hardened condition in storage, into said bone, with sufficient force to move apart fractured portions of said bone.

The invention discloses a chaotic stirring control system based on ARM single chip chaotic mapping control. The system comprises an ARM single chip which is connected and communicated with an input device, a drive chip and an AD (analog to digital) conversion chip respectively; the drive chip is connected with an H bridge drive circuit, the H bridge drive circuit is connected with a direct current motor, the direct current motor is connected with a chaotic stirring system, a sensor which monitors the rotating speed and a current signal of the direct current motor is arranged on the direct current motor, and the sensor is connected with the AD conversion chip. The system adopts a full digit circuit, has good stability and high reliability, can accurately control and conveniently adjust the rotating speed of the motor, is wide in application range, and can meet requirements of different stirring parameters under various work conditions.

Described are controlled, time-release microparticulate active and bioactive compositions (including perfuming compositions) for targeted delivery to services such as skin, hair and fabric and the environment proximate thereto, where the active and bioactive materials have a calculated log10P values of between 1 and 8 (P being the n-octanol-water partition coefficient). Such compositions include the active or bioactive material in single phase, solid solution in a wax or polymer matrix also having coated thereon and / or containing a compatible surfactant. Also described are processes and apparatus for preparing such compositions and processes for using same. Furthermore, certain component(s) of the aforementioned compositions in combination with one another are novel, and other components have novel uses in increasing fragrance substantivity.

Acoustic energy is used to control motion in a fluid. According to one embodiment, the invention directs acoustic energy at selected naturally occurring nucleation features to control motion in the fluid. In another embodiment, the invention provides focussed or unfocussed acoustic energy to selectively placed nucleation features to control fluid motion. According to one embodiment, the invention includes an acoustic source, a controller for controlling operation of the acoustic source, and one or more nucleation features located proximate to or in the fluid to be controlled.

The present invention relates to a droplet microreactor, i.e. a microreactor consisting of a droplet of a specific liquid, the microreactor being wall-less, wherein the interface of the specific liquid with the ambient environment and with the support on which the droplet is deposited defines the limits of the microreactor. The microreactor is characterized in that it consists of a droplet comprising at least one ionic liquid. The present invention also relates to methods for carrying out chemical or biochemical reactions and / or mixes using said droplet microreactor, and also to a lab-on-chip comprising a microreactor according to the invention.

An in-line-type fluid mixer is provided, which includes a first channel-forming part defining a first inlet channel from a first inlet portion to a first passage portion; a second channel-forming part defining a second inlet channel from a second inlet portion to a second passage portion; a third channel-forming part defining an outlet channel having a sectional area that increases from a narrower portion through a flaring portion to an outlet portion, and being communicated with the first inlet channel and the second inlet channel, respectively, at an end of the narrow portion; and a whirling stream-generating part for generating a whirling stream in at least one of the first inlet channel and the second inlet channel.

A method and apparatus for mixing fluids, such as beverage syrup and water, uses countercurrent injection to improve blending of the fluids. A mixing chamber has a first inlet through which a first fluid is fed to the mixing chamber, and a second inlet through which a countercurrent injection nozzle extends and is operative to inject a second fluid into a stream of the first fluid. The countercurrent injection nozzle is equipped with a check valve to control the flow of fluid into the mixing chamber. The mixing chamber may include additional inlets that may be fitted with countercurrent injection nozzles to permit the countercurrent injection of other fluid, such as flavorings, into the stream of the first fluid.

A bone cement comprising a first component and a second component, wherein contacting the first component and the second component produces a mixture which attains a high viscosity an initial period and the viscosity of the mixture remains relatively stable for a working time of at least 5 minutes after the initial setting period, and the mixture is suitable for in-vivo use.

Accordingly, in one embodiment of the invention, a bioreactor system is presented and includes a disposable container for housing biomaterials for processing, the disposable container including at least one input port, at least one exhaust port, at least one harvest port, and the integrity of the sterile environment is protected with sterile filters attached to all external open ports a structure for supporting the disposable container, one or more sensors for sensing one or more parameters of the biomaterials in the container, a heater for heating the contents of the container, the heater having a thermostat and mixing system arranged with the system such that biomaterials contained in the disposable container are mixed.

Provided are a method and apparatus for amplifying nucleic acids. The method includes introducing into a reaction vessel via different inlet channels a reactant aqueous solution containing reactants for nucleic acid amplification and a fluid that is phase-separated from the reactant aqueous solution and does not participate in amplification reaction, creating a plurality of reactant aqueous solution droplets surrounded by the fluid by contacting the reactant aqueous solution with the fluid in the reaction vessel, and amplifying the nucleic acids in the reactant aqueous solution droplets. The apparatus includes a substrate, a reaction vessel formed inside of the substrate, at least one first inlet channel formed inside the substrate, connected to an end of the reaction vessel, and allowing introduction of a reactant aqueous solution containing reactants for nucleic acid amplification into the reaction vessel, a second inlet channel formed inside the substrate, connected to the end of the reaction vessel, and allowing introduction of a fluid that is phase-separated from the reactant aqueous solution and does not participate in amplification reaction into the reaction vessel, and a heating unit installed on the substrate in such a way to thermally contact with the substrate and heating the substrate.

The present invention provides microfluidic devices and methods using the same in various types of thermal cycling reactions. Certaom devices include a rotary microfluidic channel and a plurality of temperature regions at different locations along the rotary microfluidic channel at which temperature is regulated. Solution can be repeatedly passed through the temperature regions such that the solution is exposed to different temperatures. Other microfluidic devices include an array of reaction chambers formed by intersecting vertical and horizontal flow channels, with the ability to regulate temperature at the reaction chambers. The microfluidic devices can be used to conduct a number of different analyses, including various primer extension reactions and nucleic acid amplification reactions.

The invention relates to a microfabricated device for the rapid detection of DNA, proteins or other molecules associated with a particular disease. The devices and methods of the invention can be used for the simultaneous diagnosis of multiple diseases by detecting molecules (e.g. amounts of molecules), such as polynucleotides (e.g., DNA) or proteins (e.g., antibodies), by measuring the signal of a detectable reporter associated with hybridized polynucleotides or antigen / antibody complex. In the microfabricated device according to the invention, detection of the presence of molecules (i.e., polynucleotides, proteins, or antigen / antibody complexes) are correlated to a hybridization signal from an optically-detectable (e.g. fluorescent) reporter associated with the bound molecules. These hybridization signals can be detected by any suitable means, for example optical, and can be stored for example in a computer as a representation of the presence of a particular gene. Hybridization probes can be immobilized on a substrate that forms part of or is exposed to a channel or channels of the device that form a closed loop, for circulation of sample to actively contact complementary probes. Universal chips according to the invention can be fabricated not only with DNA but also with other molecules such as RNA, proteins, peptide nucleic acid (PNA) and polyamide molecules.

Accordingly, in one embodiment of the invention, a bioreactor system is presented and includes a disposable container for housing biomaterials for processing, the disposable container including at least one input port, at least one exhaust port, at least one harvest port, and the integrity of the sterile environment is protected with sterile filters attached to all external open ports a structure for supporting the disposable container, one or more sensors for sensing one or more parameters of the biomaterials in the container, a heater for heating the contents of the container, the heater having a thermostat and mixing system arranged with the system such that biomaterials contained in the disposable container are mixed.

The apparatus for production of mixtures from two components has a container for each and devices to combine the components in the mixing space and for extrusion of the mixture. The powdered component (4) is situated in the lower part of the inner space (21), which is sealed by a bottom (10). This carries a nozzle (2) with closure membrane (3). The inner space (21) is closed on the top by the lower wall (6) and the sliding seal (8). The liquid component (9) is situated in the inner space (18) of the inner hollow cylinder (5). This is closed on the top by the upper wall (11). The lower and upper wall (6) and (11) each have an opening with sealing lips (7) and (12) that are closed by parts of the mixing rod (15). A torus (20), a section with smaller diameter (19), a mixing disk (22), as well as a mandrel (24), are present on the lower part of the mixing rod (15).

An apparatus configured for connection to a mixer for receiving a slurry and altering the flow characteristics of the slurry includes a conduit having a main inlet in slurry receiving communication with the mixer outlet and extending to a spout for discharging the slurry, at least one conduit restrictor associated with the conduit for creating back-pressure between the conduit restrictor and the mixer outlet for keeping the mixer full, and at least one pressure reducer associated with the discharge spout and configured for reducing the pressure of the slurry dispensed from the discharge spout. The apparatus is configured for maintaining a generally laminar flow from the mixer outlet to the discharge spout.

The present invention relates to a stirred-tank reactor system and methods of preparing such systems. The present invention further encompasses the use of the stirred-tank reactor system as a disposable bioreactor and in kits with disposable elements.

Microfluidic devices with multiple fluid process regions for subjecting similar samples to different process conditions in parallel are provided. One or more common fluid inputs may be provided to minimize the number of external fluid supply components. Solid materials such as chromatographic separation media or catalyst media is preferably provided in each fluid process region. Solid materials may be supplied to the devices in the form of slurry, with particles retained by porous elements or frits. Different fluid process regions may having different effective lengths, different solid material types or amounts, or may receive different ratios of common fluids supplied to the device. The flow resistances of dissimilar fluid process regions may be balanced passively with the addition of impedance elements in series with each fluid process region.

A powered surgical tool with a housing that contains a power generating unit such as a motor. A control module is disposed in a shell that is mounted in the housing. The control module contains a control circuit for regulating the actuation of the power generating unit. The power generating unit emits a signal representative of the operating state of the unit that is transmitted through the structural material forming the shell. Also internal to the control module shell is a sensor that monitors the signal emitted by the power generating unit. This signal output by the sensor is applied to the control circuit. The control circuit, based on the sensor signal regulates actuation of the power generating unit. Wherein the power generating unit is a motor, the signal emitted is the magnetic field that varies with rotor position. The sensor monitors the strength of this field.

A double-ended variable speed blower for Continuous Positive Airway Pressure (CPAP) ventilation of patients includes two impellers in the gas flow path that cooperatively pressurize gas to desired pressure and flow characteristics. Thus, the double-ended blower can provide faster pressure response and desired flow characteristics over a narrower range of motor speeds, resulting in greater reliability and less acoustic noise.

A mixing assembly for use in a semi-continuous process for producing liquid personal care compositions, such as shampoos, includes a main feed tube carrying a base of the composition to be produced, a plurality of injection tubes in selective fluid communication with the main feed tube, and an orifice provided in a wall at an end of the main feed tube downstream of the plurality of injection tubes. The wall in which the orifice is provided includes a curved (e.g., semispherical) entry surface on an upstream or inlet side of an orifice, and a curved (e.g., semi-elliptical) exit surface on a downstream or outlet side of the orifice. The orifice may have a rectangular or elliptical shape. By maintaining symmetry of the injection tubes with respect to the orifice, and leveraging delay between introduction of dosed modules and increased viscosity, effective mixing may be achieved with minimal energy.

An apparatus and method for combining multiple materials. The multiple materials may include both a major material and one or more minor materials. The major and minor materials are added at transient or steady state flow rates, depending upon a command from a control signal. The actual flow rates track the commanded flow rates, but deviate by an error. The claimed arrangement provides an instantaneous and time-based error believed to be unobtainable in the prior art.