13 results about "Lab-on-a-chip" patented technology

A system for extracting and analysing cellular material, the system comprising an integrated lab-on-a-chip (LOC) 1 and an instrument 2. The instrument comprises an interface or recess 4 for holding th

Chip laboratory cartridge (1), preferably for single use, in particular for a modular medical analysis system (20), comprising a sample chamber (2), wherein a fluorescent dye (4) is contained in the sample chamber (2) and wherein the fluorescent dye (4) is adhesive to a specific target molecule.

The invention relates to a lab-on-chip device with a modular layout for determining a plurality of biological, molecular, chemical or physical parameters relating to soil, in particular soil health and quality. Methods for using the device are also disclosed.

A Lab-On-Chip (LOC) system includes a multi-chamber tray having at least two chambers separated by a barrier, one or more light chambers each having a top portion and a bottom portion, and configured to be coupled to each chamber of the multi-chamber tray and further configured to allow selective light from the top portion of the light chamber, while blocking surrounding light, and one or more light sources, each coupled to a top portion of a corresponding one or more light chamber, wherein each of the one or more light sources is selectively configured to provide light at a predetermined wavelength, a predetermined frequency, and a predetermined intensity.

The photothermal material-based lab-on-a-chip, the molecular diagnosis method using same, and the molecular diagnosis apparatus using same according to the present invention enable highly efficient PCR to be performed within a short period of time without concerns regarding substrate effects. In addition, analyses of different targets can be carried out simultaneously, thereby providing an advantage of enabling multiplex diagnosis. Therefore, the photothermal material-based lab-on-a-chip, the molecular diagnosis method using same, and the molecular diagnosis apparatus using same according to the present invention can be used as point-of-care diagnostic tools requiring rapidity, accuracy, and multiplex diagnostic capability.

The present disclosure provides a cartridge for Lab-On-Chip applications. An example cartridge for Lab-On-Chip applications includes a first module that is including: at least one desiccant storage chamber, a dry-reagent storage chamber, a fluidic circuit fluidically connected to the dry-reagent storage chamber, a first air path connecting the dry-reagent storage chamber to the desiccant storage chamber and comprising a membrane that prevents liquid flow from the dry-reagent storage chamber to the desiccant storage chamber. The cartridge further comprises a second module including a container having an internal cavity for holding a liquid solution. The first module and the second module are adapted to be fluidically coupled to one another.

The present disclosure concerns open-end carbon nanotubes assembled as a microelectrode array in electrode sets / micro-electrode sets (ES / micro-ES). The ES / micro-ES includes three electrodes that are made of highly densified multi-walled carbon nanotubes fibers (HD-CNTfs) sectioned into rods embedded in an inert polymer film with exposed open ends of CNTs at the electrode-electrolyte interface. The ES / micro-ES provide miniature electrochemical sensing devices in which all electrodes are based on carbon nanomaterials. The combination of dimensions and orientation provides for highly sensitive electrochemical determination (picomolar) of different electroactive analytes in different electrolyte mediums, where even a single drop of desired analyte solution will be enough for electrochemical characterization.

The present invention relates generally to the field of nucleic acid isolation on silica solid supports. In particular, disclosed herein is a novel silica-solid support binding nucleic acid buffer chemistry based on the use of small tetrameric organic compounds, such as tetramethylammonium chloride (TMAC), under acidic conditions. This novel nucleic acid purification chemistry not only purifies RNA, but also DNA, and has the potential to be implemented in a wide variety of commercial kits, from spin columns to Lab-On-A-Chip (LOC) devices, such as disposable cartridges utilizing solid phase extraction technology. Furthermore, the present method can use relatively small volumes of binding buffer and thus can be performed in such integrated or closed molecular diagnostic devices, which have the potential to allow for increased sample input volumes, which for liquid biopsy samples such as plasma or urine, can increase the chances of detecting rare nucleic acid targets.

Method for producing a welded joint 20 in a chip laboratory cartridge (40), preferably for single use, in particular for a modular medical analysis system, between a Si-chip (1) which has microcavities (13) in which active substances (14) for an analysis reaction are contained and a thermoplastic plastic carrier component (2), preferably made of polycarbonate, comprising the process steps: positioning the Si-chip (1) containing the active substances in a recess (5) of the thermoplastic plastic carrier component (2) in which the Si-chip (1) rests at least partially on the thermoplastic plastic carrier component (2), applying a hold-down force (N) to the Si-chip (1) by means of a hold-down device, producing the welded joint (20).

A chip lab cartridge, preferably for single use, in particular for a modular medical analysis system, has a layer structure with a pneumatic layer and a fluidic layer, which are arranged in layers in an extension plane and are separated by an elastic membrane. The pneumatic layer and the fluidic layer form a first cavity, which is formed in a first part in the pneumatic layer and in a second part in the fluidic layer. A first sample chamber is bounded by the elastic membrane and is formed in the first cavity, which is connected in a fluid-conducting manner to a first fluid channel and a second fluid channel formed in the fluidic layer. A liquid is introduced into the first sample chamber by the first fluid channel and / or the second fluid channel.

A filter device for an optical module for a lab-on-a-chip analysis device, in which the optical module has a light path, includes a support element, a filter support, and a drive device. The support element can be mounted in the optical module. The filter support is arranged so that it can move on the support element. The filter support also has a first filter region and a second filter region. The drive device is configured such that the filter support can move between a first position in which the first filter region is arranged in the light path, and a second position in which the second filter region is arranged in the light path.

The present disclosure provides a cartridge for lab-on-chip applications. An example cartridge for lab-on-chip applications includes a first module including: at least one desiccant storage compartment; a dry reagent storage chamber; a fluid circuit fluidly connected to the dry reagent storage chamber; and a first air path connecting the dry reagent storage chamber to the desiccant storage chamber and including a film preventing liquid flow from the dry reagent storage chamber to the desiccant storage chamber. The cartridge also includes a second module including a container having an interior cavity for containing the liquid solution. The first module and the second module are adapted to be fluidly coupled to each other.

Chip laboratory cartridge (1), preferably for single use, in particular for a modular medical analysis system, comprising a layer structure (25) with a pneumatic layer (2) and a fluidic layer (3), which are arranged in a layered arrangement in a plane (E) and separated by an elastic membrane (4), wherein the pneumatic layer (2) and the fluidic layer (3) form a first cavity (5a), which is formed into a first part (6) in the pneumatic layer (2) and into a second part (7) in the fluidic layer (3), wherein a first sample chamber (8a), bounded by the elastic membrane (4), is formed in the first cavity (5a), which is fluidly connected to a first fluid channel (19) and a second fluid channel (20) formed in the fluidic layer (3), wherein a liquid is introduced into the first sample chamber (8a) by means of the first fluid channel (19) and / or the second fluid channel (20). can be initiatedwherein the pneumatic layer (2) has a pneumatic channel (18) by means of which the first part (6) of the first cavity (5a) can be pressurized with a negative or positive pressure, such that the elastic membrane (4) can be variably displaced in the first cavity (5a), so that the volume of the first sample chamber (8a) can be variably adjusted between a minimum volume and a maximum volume.