Automatic device for quantitatively distributing microfluid and using method

A quantitative distribution and microfluidic technology, applied in chemical instruments and methods, analytical materials, laboratory containers, etc., can solve the problems of difficulty in precise control of droplet size and low quantitative accuracy, and achieve simple processing and simple device structure. , the effect of improving quantitative accuracy
CN101486004AInactive Publication Date: 2009-07-22SHANGHAI INST OF MICROSYSTEM & INFORMATION TECH CHINESE ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHANGHAI INST OF MICROSYSTEM & INFORMATION TECH CHINESE ACAD OF SCI
Publication Date
2009-07-22
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a method and a device for automatically and quantitatively distributing a microfluid. The method uses surface tension of liquid in a leading position under a micron scale to be combined with flow shearing action of the other fluid which is insoluble with the fluid so as to make a sample liquid filled and positioned in a microcavity with certain volume, thereby realizing quantitative distribution of the sample liquid. The device by the method is formed by at least one microchannel and a group of micro-fluidic chips of the microcavity, wherein the microcavity is positioned on the side of the microchannel and is communicated with the microchannel; the sample liquid in the microchannel enters and is filled in the microcavity through the surface tension; and then, residual sample liquid in the microchannel is removed by the flow shearing action of the other fluid which is insoluble with the liquid, and the sample liquid is just filled in the microcavity, so that quantitation and distribution of sample liquid droplet can be realized. The invention provides simple, quick and high-flux method and device for automatically and quantitatively distributing the microfluid, and can be applied to a micro-biochemical reactor and a chip laboratory.
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Description

technical field

[0001] The invention relates to a microfluid automatic quantitative distribution device and a using method, which can be applied to microbiochemical reactors and chip labs. Background technique

[0002] In recent years, microfluidic chips, as a new technology platform, have received widespread attention in the fields of biology and chemistry, because compared with macroscopic systems, microfluidic chips have many outstanding advantages in practical applications, such as: (1) Low cost: Due to the miniaturization of the fluid system, the amount of reagents and samples required in the detection analysis and reaction synthesis process is greatly reduced (usually in nanoliters or picoliters), and the energy consumption is lower, which reduces the operating cost; on the other hand, the system The integration and automation of the system greatly reduces the manual participation and thus reduces the labor cost. (2) Fast speed: The short diffusion path and large surf...

Claims

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