The invention discloses a hollow spherical valve plug and a manufacturing method thereof. The valve plug comprises a main body and an inner sleeve pipe, wherein the inner sleeve pipe penetrates through the main body, the main body is a hollow spherical body which is formed by symmetrically welding a stainless steel left hemisphere and a stainless steel right hemisphere, the inner wall of the hollow spherical body is provided with a reinforcing block, an opening which penetrates through the outer wall and the reinforcing block of the main body is arranged on the main body, the valve plug is cut into a disc plate type blank by a stainless steel plate, the blank is rotatably pressed or drawn to be the left hemisphere and the right hemisphere, the left hemisphere and the right hemisphere are welded to be the hollow spherical main body, the reinforcing block is welded on the inner wall of the main body, a stainless steel seamless pipe is manufactured into an inner sleeve pipe which is pressed into the main body, the opening is arranged on the main body which is provided with the reinforcing block, and a hollow spherical valve plug finished product is formed by mechanically cutting the main body and polishing the surface of the main body. The hollow spherical valve plug is formed by welding the hollow hemispheres made of stainless steel materials, has simple technology and strong exploitativeness, high corrosion resistance, high wear resistance, long service life, stable structure and high strength and is easy to obtain use materials.