The application discloses an application of an endoscopic continuous suturing device in preparation of a gastric plication suturing medical instrument, and the endoscopic continuous suturing device comprises a suture wire with uniformly distributed barbs, a plurality of
titanium clips and a pushing device, the suture wire is 6-10 cm long, and the two ends of the suture wire are respectively provided with a front end connecting ring and a rear end connecting ring; a sheath
pipe is arranged at the position close to the rear end connecting ring of the suture wire; the
titanium clip is used for clamping and fixing the
gastric mucosa tissue and the suture wire; the pushing device is used for tightening the suture wire and comprises a traction steel wire, an inner push tube and an outer sheath tube which are sleeved from inside to outside and slide; a
metal hook is arranged at the front end of the traction steel wire; two operation handles are arranged at the rear end of the pushing device and are used for respectively controlling the inner push tube and the traction steel wire to move forward and backward. The
gastric mucosa is sutured by the
barbed suture wire, the long-term stability of the
gastric wall folding is ensured, the
barbed suture wire cooperates with the
titanium clip to realize step-by-step pre-tightening, and the
gastric cavity volume can be accurately controlled.