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41 results about "Vaginal mucosa" patented technology

Deep folds of mucous membrane (the vaginal mucosa) line the vagina. The folds, called rugae, give the vagina its ability to expand. The vaginal muscles also relax to extend the depth (length) of the vagina, facilitating SEXUAL INTERCOURSE.

Device for treatment of incontinence

PendingUS20260014373A1Anti-incontinence devicesGymnastic exercisingElectro stimulationIntra abdominal pressure
The present invention relates to a device for the prevention and / or treatment of fecal and / or urinary incontinence. The device may fit into a vagina. The device may include a pressure sensor and electrodes. The device may include a lateral projection on the device and / or a skin of the device. In response to intra-abdominal pressure the device may apply electrostimulation with the electrodes, for example to a vaginal mucosa.
Owner:FEMME MEDICAL LTD

Lactobacillus acidophilus FMM01 with effects of improving contractility of pelvic floor muscles and repairing mucous membranes and application of lactobacillus acidophilus FMM01

The invention discloses a lactobacillus acidophilus FMM01 with the effects of improving the contractility of pelvic floor muscles and repairing mucous membranes and application of the lactobacillus acidophilus FMM01, the lactobacillus acidophilus FMM01 is preserved in the China Center for Type Culture Collection, the preservation date is January 9, 2024, and the preservation number is CCTCC NO: M2024052. The lactobacillus acidophilus FMM01 has the advantages of self-adaption, high acid resistance, strong mucous membrane adhesiveness and no irritation to vaginal mucosa. The lyophilized powder is high in activity and excellent in stability; experimental results show that the lactobacillus acidophilus FMM01 can effectively inhibit bacteria, and especially can effectively inhibit enterobacter cloacae, vibrio parahaemolyticus and / or candida albicans. Besides, the lactobacillus acidophilus FMM01 can improve vaginal relaxation, improve pelvic floor muscle contractility and / or recover vaginal mucosa functions, can promote recovery of healthy florae after mixed vaginitis antibiotic / hormone treatment, improves the treatment effect of mixed vaginitis, and remarkably reduces the recurrence rate of mixed vaginitis.
Owner:JIANGSU KERONG BIOPHARMACEUTICAL CO LTD

A gynecological gel for inhibiting bacteria, regulating microecological balance and tightening in vagina and a preparation method thereof

The present application belongs to the technical field of daily chemical preparation, and particularly relates to a gynecological gel for inhibiting bacteria, regulating microecological balance and tightening vagina and a preparation method thereof. The gynecological gel comprises the following raw materials in mass fractions: 0.5-1 parts of carbomer, 0.04-0.09 parts of sodium hydroxide, 1-3 parts of collagen, 0.01-0.06 parts of sodium hyaluronate, 0.5-1.5 parts of isomaltooligosaccharide, 2-5 parts of propylene glycol, 0.05-0.3 parts of hydroxybenzoic acid methyl ester, 0.02-0.15 parts of hydroxyphenyl ethyl ester, 0.1-1.5 parts of hydrogenated lecithin, 1-6 parts of 1,3-butanediol, 3-5 parts of glycerol, 0.5-1 part of xanthan gum and 70-90 parts of water. The present application uses buckwheat filtrate to prepare collagen, and the active ingredients in the buckwheat filtrate can penetrate the cell membrane of pathogenic bacteria to play an antibacterial role; the collagen can repair the vaginal mucosa barrier and reduce the adhesion and invasion of pathogenic bacteria; therefore, after being compounded with the raw materials such as carbomer, sodium hydroxide, sodium hyaluronate, isomaltooligosaccharide and propylene glycol, the multiple components can synergistically promote the synthesis and repair of collagen fibers and improve the elasticity of tissues.
Owner:HUNAN MICRO PEPTIDE BIOMEDICAL CO LTD

Combination of lactobacillus rhamnosus LRa05, lactobacillus acidophilus La88 and lactobacillus plantarum Lp90 and application of combination in regulation of vaginal mucosal barrier protein

The invention relates to the field of prevention and treatment of vaginitis, in particular to a composition of lactobacillus rhamnosus LRa05, lactobacillus acidophilus La88 and lactobacillus plantarum Lp90 and application of the composition to regulation of vaginal mucosa barrier protein. The lactobacillus rhamnosus LRa05 is a lactobacillus rhamnosus LRa05 with the preservation number of CGMCC (China General Microbiological Culture Collection Center) NO.24377, and the lactobacillus rhamnosus LRa05 is a lactobacillus rhamnosus LRa05 with the preservation number of CGMCC NO.24377. The lactobacillus acidophilus La88 is the lactobacillus acidophilus La88 of which the preservation number is CGMCC (China General Microbiological Culture Collection Center) NO.24109, and the lactobacillus acidophilus La88 is a lactobacillus acidophilus La88 of which the preservation number is CGMCC NO.24109. The lactobacillus plantarum Lp90 is the lactobacillus plantarum Lp90 with the preservation number of CGMCC (China General Microbiological Culture Collection Center) NO.10453, and the lactobacillus plantarum Lp90 has the preservation number of CGMCC NO.10453. The lactobacillus rhamnosus LRa05, the lactobacillus acidophilus La88, the lactobacillus plantarum Lp90 and the combination thereof disclosed by the invention can regulate the expression of the vagina mucosal barrier protein.
Owner:WUHAN WEIKANG PROBIOTICS RES INST CO LTD +1

Antibacterial gel and preparation method thereof

The invention relates to an antibacterial gel and a preparation method thereof. The gel mainly comprises silver ions, avocado oil, a radix puerariae extract, wheat germ oil, emulsifying wax, a folium artemisiae argyi extract, glycerol, a styrene / butadiene copolymer, purified water and hydroxyethyl cellulose. Extracts containing specific small-molecule polypeptides are extracted from Artemisia rubescens and Radix Puerariae through a specific extraction method, and the polypeptides are Artemisia rubescens polypeptides (SEQ ID No: 1) and Radix Puerariae polypeptides (SEQ ID No: 2) respectively. The extracts have a synergistic effect with silver ions, so that the antibacterial effect of the gel is remarkably improved, and particularly, the gel has a remarkable inhibiting effect on staphylococcus aureus, escherichia coli and candida albicans. The bacteriostatic gel is simple in preparation method, convenient to use and suitable for bacteriostasis of female vaginal mucosa and maintenance of vaginal micro-ecological internal environment.
Owner:YUNNAN SHUANGSHANG IND CO LTD +1

An in-vitro model of human vaginal micro-ecosystem, a construction method and application thereof

PendingCN122381991ABiotechnologyIn vitro study
The application discloses a human vagina micro-ecological in-vitro model and a construction method and application thereof, and relates to the technical field of medicines.The application discloses a human vagina micro-ecological in-vitro model and a construction method and application thereof.Firstly, a mixed cell group of the vaginal epithelium containing a complete cell lineage and capable of long-term subculture is successfully established, a technical bottleneck that primary vaginal epithelial cells are difficult to expand is solved, and ideal seed cells are provided for model construction.Secondly, a highly-bionic vaginal mucosa model having a tight connection structure, rich layers and an orderly arrangement is constructed, and the physiological barrier and immune regulation functions of the vaginal mucosa are truly simulated.Finally, by introducing lactobacillus symbiosis and confirming the response to estrogen, a multi-element in-vitro research model integrating the anatomical structure of the vagina, resident flora, local immunity and endocrine regulation is constructed, and a reliable technical platform is provided for in-depth exploration of the mechanism of vaginal micro-ecological disorder and efficient screening of related drugs.
Owner:BEIJING OBSTETRICS & GYNECOLOGY HOSPITAL CAPITAL MEDICAL UNIV

Type III collagen and beta-glucan composition and application thereof in repairing vaginal mucosal injury

The invention discloses a composition of type III collagen and beta-glucan and application of the composition in repairing vaginal mucosa injury, and belongs to the technical field of biological medicine, and the composition comprises the following effective components: type III collagen with the concentration of 0.3-1.8 mg / mL and beta-glucan with the mass concentration of 0.1-0.8%. The collagen III provides structural support required by tissue repair, the beta-glucan improves inflammation microenvironment, regulates immune response and jointly promotes proliferation and migration of damaged vaginal epithelial cells, the cell proliferation rate and the scratch healing rate are far higher than those of a group using any component independently, and rapid repair of mucosal lesions can be achieved.
Owner:SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV

Mussel mucoprotein physical barrier protective gel and preparation method thereof

The invention belongs to the technical field of gel preparation, and particularly relates to mussel mucoprotein physical barrier protective gel and a preparation method thereof. The mussel mucin polymer disclosed by the invention can quickly form a compact and flexible isolating membrane with self-repairing capability on the surface of vaginal mucosa. The isolating membrane can be firmly attached to the surface of a mucous membrane based on the strong biological adhesiveness of mussel mucin, can directly block sperm penetration and limit sperm swimming, and also can effectively block pathogenic microorganisms such as viruses and bacteria from contacting the mucous membrane. The acid environment provided by the lactic acid-citric acid buffer system not only can directly inhibit sperm activity, but also can enhance the stability and adhesiveness of the mussel mucin polymer, so that the mussel mucin polymer can be better attached to vaginal mucosa, and the action time of a physical barrier is prolonged. The chitosan quaternary ammonium salt has the effects of killing bacteria and viruses and the like, and the hydroxypropyl methyl cellulose serving as a thickening agent can improve the viscosity and the stability of the gel, so that the gel can be better retained in the vagina, and the action time is prolonged.
Owner:HENAN YIWEIYI IND CO LTD

Methods of treatment using topical roflumilast compositions

PCT designated stageWO2025265054A3Emulsion deliveryDermatological disorderRheumatologic diseaseHypomelanoses
Methods of treating a patient suffering from one or more of epidermal disorders of persistent inflammation—cell kinetics and differentiation disorders, epidermal disorders of persistent inflammation—altered reactivity disorders, disorders of the lips, oral, or vaginal mucosa, epidermal disorders of cohesion—vesicular and bullous disorders, cutaneous lymphomas, skin manifestations of rheumatologic diseases, hypomelanoses and hypermelanoses, or skin manifestations related to oncology treatments. The methods include topical administration of a pharmaceutical composition comprising a therapeutically effective amount of roflumilast.
Owner:ARCUTIS BIOTHERAPEUTICS INC

Temperature-sensitive poloxamer gel for preventing vaginal radiation injury and preparation method of temperature-sensitive poloxamer gel

The invention provides temperature-sensitive poloxamer gel for preventing vaginal radiation injury and a preparation method of the temperature-sensitive poloxamer gel, and belongs to the technical field of medical gel. The temperature-sensitive type poloxamer gel is prepared from the following components: 6 percent to 18 percent of a poloxamer compound, 3 percent to 8 percent of a functional component, 0.01 percent to 0.08 percent of a penetration enhancer, 0.10 percent to 0.45 percent of a regulator, 0.13 percent to 0.25 percent of a humectant, 0.05 percent to 0.12 percent of a preservative and the balance of water, the poloxamer compound is prepared by compounding poloxamer 407 and poloxamer 188, and the poloxamer compound is prepared by compounding the poloxamer 407 and the poloxamer 188. The temperature-sensitive poloxamer gel for preventing the vaginal radiation injury, disclosed by the invention, is relatively long in retention time at an acting part, has a certain slow release effect, can keep long-time stimulation to vaginal mucosa, is beneficial to rapid healing of a wound surface, can effectively prevent radioactive vaginitis, is convenient to use, and is safe and non-irritant to a human body.
Owner:JILIN UNIV FIRST HOSPITAL

Mucoadhesive composition for vaginal use

PendingEP4670709A1Aerosol deliveryOintment deliveryPhysiologyVaginal dryness
The present invention describes a composition for vaginal, preferably intravaginal, use for the prevention and treatment of vaginal conditions, with mucoadhesive, soothing, moisturizing and pH-regulating properties. By remaining adherent to the vaginal mucosa for prolonged periods, the composition according to the invention is therefore able to alleviate pain, burning and itching, often resulting from vaginal dryness, to promote the rebalancing of the vaginal bacterial flora, to restore the natural pH, to combat vaginal atrophy, vaginosis, vaginitis, to reduce local irritation of the tissues and to combat the proliferation of pathogens.
Owner:NIRIAL PHARMA SRL

Baicao gynecological inflammation clear water gel and preparation method thereof

The invention relates to the technical field of medical treatment, in particular to herbal gynecological inflammation clear water gel, which is prepared from the following components in percentage by mass: 14 percent of traditional Chinese medicine extracting solution, 47.5 percent of matrix and 38.5 percent of matrix, the matrix 1 is N, O-carboxymethylated chitosan, and the matrix 2 is L-leucine. The hydrogel preparation adopted by the invention can be tightly attached to the surface of a vaginal mucosa by virtue of a specific three-dimensional network structure and good elasticity, so that more uniform coating and more lasting retention are realized, the loss of medicinal components caused by the self-cleaning effect of the vagina is reduced, and the effect that the medicine can continuously act on an inflammation part is ensured; the hydrogel prepared by the method is soft in texture, high in biocompatibility, almost free of irritation and foreign body sensation after being used and smoother and milder in administration process, and the comfortable use experience is beneficial to relieving psychological burdens of patients and enhancing trust and cooperation of the patients with treatment schemes.
Owner:GUIZHOU CHANGSHENG PHARM CO LTD

Anti-HPVHIV human body lubricating liquid

PendingCN121371329ASurgeryBetaineActive agent
The present invention discloses an anti-HPVHIV human body lubricating liquid, and relates to the technical field of biological medicine, the anti-HPVHIV human body lubricating liquid is prepared from the following raw materials by weight: 0.1-20 parts of sodium hyaluronate with a molecular weight of 10,000-25,000 Da; 20 to 99 parts of purified water; 0.01 to 10 parts of sodium dihydrogen phosphate; 1 to 10 parts of water; 0.1 to 20 parts of glycerol; 0.01 to 10 parts of a surfactant; the surfactant is one or more of betaine, lauryl sodium sulfate and Tween 80, and the molecular weight of the sodium hyaluronate is 0.5 million to 1.5 million Da. The anti-HPVHIV human body lubricating liquid has dual effects, on one hand, a physical membrane is formed through sodium hyaluronate, and HPV viruses and HIV viruses are prevented from infiltrating host cells of a vaginal mucosa base layer;
Owner:SUZHOU FUDA BIOMEDICAL TECH CO LTD

Stem cell nano-vesicle gel preparation and application thereof

The invention provides a gel preparation, the gel preparation comprises a reverse-phase temperature-sensitive hydrogel matrix and bioactive vesicles, and the reverse-phase temperature-sensitive hydrogel matrix comprises a water-soluble matrix material and a reverse-phase temperature-sensitive material. The gel preparation disclosed by the invention can be used for regulating local immune response at a radioactive vaginal mucosa injury part, reducing secretion of inflammatory factors, repairing non-target cell DNA injury caused by radiotherapy and efficiently promoting recovery of the radioactive vaginal mucosa injury, so that an efficient and safe radioactive vaginal mucosa injury treatment strategy is provided for clinical application; the clinical problems that the radioactive vaginal mucosa injury is low in cure rate, easy to relapse and the like are fundamentally solved.
Owner:NANJING SAILIKANG BIOMEDICAL TECHNOLOGY CO LTD

A vaginal injection device

The patent discloses a kind of vaginal injection devices, it is related to medical injection field, device includes base and expansion board, expansion board can slide along the sliding slot on base, reach the function of vaginal speculum by the expansion of expansion board, make expansion board adhere to vaginal mucosa;Base has handle for fixing entire injection device;Expansion board has several needle holes, injection needle can be worn from needle hole and carry out drug injection;Needle and medicine bin are connected, medicine bin and needle are closed space, fill the medicine needed to be injected in;The length of needle that entire medicine bin is adjusted to be worn needle hole is adjusted by the movement of gear and gear sliding slot, the depth of drug injection into vaginal mucosa;The new type of patent does not need to use vaginal speculum to assist injection in vagina during use process, can accurately control the depth of drug injection, complete the injection of entire vaginal mucosa once, shorten operation time, improve injection efficiency, reduce drug waste, improve curative effect, reduce patient pain.
Owner:郑波

A compound preparation for nourishing and maintaining the vagina and pelvic floor muscles by using plant fermented lactic acid bacteria lysate

This invention discloses a compound preparation of plant-fermented lactic acid bacteria lysate for nourishing and protecting the vaginal pelvic floor muscles. By weight, it comprises the following components: kidney bean-honeysuckle fruit compound ferment: 4-8 parts; pomegranate peel-derived lactic acid bacteria lysate: 5-9 parts; bamboo fungus mycelium extract: 3-7 parts; compound sophorolipid: 6-8 parts; sodium hyaluronate: 2-5 parts; total glycosides of Centella asiatica: 1-3 parts; glycerin: 5-10 parts; lactic acid: 1-2 parts; purified... Water: 36-45 parts; Carbomer 940: 2-4 parts; Trehalose: 1-3 parts; Chitosan: 1-3 parts; Methylchloroisothiazolinone: 0.1-0.3 parts; Sodium hydroxide: 0.1-0.2 parts; This invention can regulate the vaginal microecological balance, nourish the vaginal mucosa, enhance the toughness of pelvic floor muscle fibers, and promote the repair of pelvic floor muscle damage, solving the technical problems of existing preparations having single function, weak targeted pelvic floor muscle care, and easy disruption of the vaginal microecology.
Owner:YUANSHENGMEI (SHENYANG) REGENERATIVE MEDICINE TECHNOLOGY CO LTD

Gynecological bacteriostatic hydrogel and preparation method thereof

PendingCN122321043ASalvia miltiorrhizaViola yedoensis
This invention discloses a gynecological antibacterial hydrogel, its preparation method, and its application. The hydrogel comprises a water extract of traditional Chinese medicines including Verbena officinalis, Salvia miltiorrhiza, Portulaca oleracea, Sophora flavescens, Viola yedoensis, Phellodendron chinense, and Artemisia argyi, as well as lactic acid, chitosan, and water. The preparation involves a water extraction and alcohol precipitation purification process to obtain the herbal extract, which is then mixed with a chitosan-lactic acid swelling matrix, adjusted to pH 3.8-4.4, and then filled and sterilized. Based on the principles of traditional Chinese medicine (TCM) formulation and combined with modern pharmaceutical technology, this invention's gel possesses the effects of clearing heat and drying dampness, detoxifying and killing parasites, and promoting blood circulation and removing blood stasis. It exhibits strong inhibitory activity against common gynecological pathogens, restores the acidic environment of the vagina, regulates local immunity and microenvironment, has an adjunctive therapeutic effect on HPV infection, is non-irritating to the vaginal mucosa, and has high safety and good stability.
Owner:HEZHENG (LINYI) BIOTECHNOLOGY CO LTD

Vagina tightening bacteriostatic preparation and preparation method thereof

The invention relates to the technical field of medicine, in particular to a vagina tightening bacteriostatic preparation and a preparation method thereof.The vagina tightening bacteriostatic preparation is prepared from, by mass, 0%-0.5% of carbomer, 5%-13% of galactomannan, 1%-6% of transient pink regulator, 0.1% of tetrahydropiperine, 4% of physalis alkekengi extracting solution and 10% of composite plant fungicide; the amount of the neutralizer is the amount which enables the pH value of the preparation to be 6.0-6.5. According to the invention, the galactomannan instantly forms a film to tighten and shrink vagina, the instant plicatin rapidly thickens vagina mucosa, the plant penetrant tetrahydropiperine promotes permeation of effective components and increases the mucosa absorbance of the effective components, so that the vagina shrinking effect is multiplied, and the plant penetrant tetrahydropiperine cooperates with other various components to achieve a synergistic effect, so that the vagina shrinking effect is improved. And a rapid and efficient vagina contracting effect is achieved.
Owner:GUANGZHOU BAIYUTANG PHARM TECH CO LTD

Foaming agent for adjusting vagina pH and preparation method thereof

The invention relates to the field of pharmaceutical preparations, in particular to a foaming agent for vagina pH adjustment and a preparation method thereof. The foaming agent comprises the following components in parts by weight: 5-8 parts of lactobacillus microcapsules, 1-2 parts of fructo-oligosaccharide, 3-4 parts of glycogen, 0.2 part of phlorizin, 2 parts of lactic acid, 1 part of citric acid, 0.5 part of sodium citrate, 8-10 parts of a propellant, 3.0 parts of sodium alginate and the balance of water, wherein the total parts by weight of the components are 100. The lactobacillus microcapsule is prepared from the following components: lactobacillus, trehalose and chitosan. According to the present invention, the micro-ecology can be rapidly recovered on the basis of the direct killing of pathogenic microorganisms by using the conventional treatment drug in the spaced cooperation manner; the lactobacillus microcapsules can effectively protect stable existence of lactobacillus before colonization in vaginal mucosa; the fructo-oligosaccharide and the glycogen provide substrates for the lactobacillus, help the lactobacillus to proliferate quickly, continuously maintain an acid environment and eliminate pathogenic bacteria through competitive inhibition.
Owner:NANJING DICHANG PHARM TECH CO LTD

In vitro recombinant vaginal mucosa model and construction method and application

PendingCN122357424ATissue architectureIntercellular connection
This application discloses an in vitro reconstructed vaginal mucosa model, its construction method, and its application. The construction method includes an improved culture medium: HVU medium is added to immortalized vaginal epithelial cell line VK2 / E6E7, which is then seeded into Transwell chambers and cultured. The HVU medium on the surface of the culture in the Transwell chambers is aspirated, and the Transwell chambers are raised to the air-liquid interface for air-liquid surface culture. The culture medium is then replaced with HVA medium to obtain the vaginal mucosa model. This method improves the stability of cells during in vitro culture and constructs an in vitro reconstructed vaginal mucosa model with a tissue structure highly similar to human vaginal mucosa (possessing a complete stratified squamous epithelial structure and normal intercellular connections), thereby enhancing the model's physiological functional simulation.
Owner:博溪生物科技(苏州)有限公司

Lactobacillus crispatus and application thereof

The invention belongs to the technical field of microorganisms, and particularly relates to lactobacillus crispatus and application thereof in female genital tract health. The preservation number of the strain is CCTCC NO: M20231720, and the strain is excellent in antibacterial ability and vaginal mucosa adhesion ability, can effectively generate hydrogen peroxide, has no potential safety problem, and plays an important role in regulating genital tract micro-ecological balance and preventing and treating exogenous pathogenic bacterium infection.
Owner:CHENGDU BEITEYI KANGEN BIOMEDICAL TECHNOLOGY CO LTD

Methods of treatment using topical roflumilast compositions

PCT designated stageWO2025265054A2Emulsion deliveryDermatological disorderRheumatologic diseaseHypomelanoses
Methods of treating a patient suffering from one or more of epidermal disorders of persistent inflammation—cell kinetics and differentiation disorders, epidermal disorders of persistent inflammation—altered reactivity disorders, disorders of the lips, oral, or vaginal mucosa, epidermal disorders of cohesion—vesicular and bullous disorders, cutaneous lymphomas, skin manifestations of rheumatologic diseases, hypomelanoses and hypermelanoses, or skin manifestations related to oncology treatments. The methods include topical administration of a pharmaceutical composition comprising a therapeutically effective amount of roflumilast.
Owner:ARCUTIS BIOTHERAPEUTICS INC

Uniknot continuous suture method for postpartum perineum anatomy reconstruction

The invention discloses a uniknot continuous suturing method for postpartum perineum anatomy reconstruction, and relates to the field of medical suturing methods, the uniknot continuous suturing method comprises the following steps: S1, initial suturing and fixing; s2, continuously suturing vaginal mucosa and involution hymen rings; s3, continuously suturing the perineum subcutaneous tissue; s4, performing continuous intradermal sewing; s5, rebuilding navicular fossa, and selecting a forward stitching method or a reverse stitching method according to the operation field direction to realize three-dimensional fine involution; and S6, removing residual lines and checking. According to the method, an integrated suturing mode of single knot starting and continuous walking is adopted, the postpartum perineum suturing operation process is simplified, the suturing operation time is shortened, the number of knots is reduced, and tissue foreign matter reaction and postoperative pain are reduced. According to the method, three-dimensional fine involution of key anatomical structures of the perineum is achieved through the specific navicular fossa reconstruction step, complications such as traumatic granuloma hyperplasia, scar contracture and poor healing of the perineum can be effectively prevented, long-term fast recovery of anatomical forms and functions of puerperae is guaranteed, and good clinical benefits are achieved.
Owner:YANTAI YUHUANGDING HOSPITAL

Device for preventing postpartum uterine prolapse

The invention provides a device for preventing postpartum uterine prolapse, and belongs to the technical field of postpartum care. Comprising a support, a connecting part is arranged at the top of the support, a supporting shell is arranged at the top of the connecting part, the surface of the supporting shell is sleeved with a rubber sleeve, a cavity is formed in the supporting shell, and T-shaped bandages are arranged at the four corners of the support. By arranging the support, the supporting shell, the rubber sleeve and the T-shaped bandage, stable in-vitro physical supporting of pelvic floor muscles of a patient can be achieved, the infection risk in the vagina is reduced while the burden of the pelvic floor muscles is effectively relieved, the completeness of the vaginal mucosa barrier is protected, the discomfort of postpartum nursing of the patient is reduced, and the rehabilitation progress of the patient is accelerated.
Owner:CHENGDE MEDICAL UNIV

Vagina nourishing and nursing gel and preparation method thereof

PendingCN122005419ACosmetic preparationsToilet preparationsBiotechnologyDextranomer hyaluronic acid
The invention relates to the technical field of gel, in particular to vagina nourishing and nursing gel and a preparation method thereof.The vagina nourishing and nursing gel is prepared from a composite extract, a mixed extract, a lactobacillus fermentation product, collagen, argireline, oligopeptide-1, trehalose, glucan, sodium hyaluronate, sclerotium gum, carbomer, glycerin, 1, 3-propylene glycol, PEG-400, 1, 2-hexanediol, p-hydroxyacetophenone, lactic acid and water; the composite extract is prepared by mixing four raw materials including polysaccharide powder and polyphenol purified substances. The mixed extract is prepared by mixing four raw materials including flavone powder and alkaloid powder; all the components have a synergistic effect, are mild and safe and can maintain the health state of the vagina. The extraction process is efficient and environment-friendly, improves the raw material utilization rate, reduces the cost and is suitable for industrial production; the product formula is mild and non-irritant, all the components have a synergistic effect, the vaginal mucosa can be repaired, micro-ecological balance can be adjusted, the long-term private maintenance requirement of women is met, and the advantages are remarkable.
Owner:CHENGDU YUZE CHINESE MEDICINE BIOLOGICAL TECH

Traditional Chinese medicine composition with antibacterial effect and application

PendingCN121265691AAntibacterial agentsAntimycoticsBiotechnologyCnidium monnieri
The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition with an antibacterial effect and application, the traditional Chinese medicine composition comprises 20-25 parts of rheum officinale, 25-30 parts of dandelion, 15-20 parts of sanguisorba officinalis, 10-15 parts of coptis chinensis, 15-20 parts of golden cypress, 15-20 parts of radix sophorae flavescentis, 15-20 parts of fructus cnidii, 10-15 parts of polygonum cuspidatum and 10-15 parts of cortex dictamni; the traditional Chinese medicine composition is prepared into traditional Chinese medicine composition lotion and powder, the antibacterial effect of the traditional Chinese medicine composition lotion and powder is remarkably higher than that of a control group 1 and that of a control group 2, and the traditional Chinese medicine composition lotion and powder have remarkable difference; the bacteriostasis rate reaches 85% after 5 min of action, and it is proved that the antibacterial stability is good; the vagina mucosa of the domestic rabbits in the experimental group is normal in form, free of hyperemia and swelling, free of irritation and wide in clinical application prospect.
Owner:NINGXIA RUIRONGLIN BIOTECHNOLOGY CO LTD

Clinical medicine applying device for obstetrics and gynecology department

PendingCN121754792ASurgeryMedical devicesMechanical engineeringVaginal mucosa
The invention discloses a clinical medicine applying device for gynaecology and obstetrics, and relates to the technical field of clinical medicine applying for gynaecology and obstetrics, the clinical medicine applying device comprises a fixed seat, and a vaginal dilation follow-up spray mirror positioning mechanism is arranged on one side of the fixed seat. According to the clinical medicine applying device for the obstetrics and gynecology department, by arranging the vaginal dilation follow-up type spraying mirror positioning mechanism, linkage of vaginal dilation action and spraying mirror assembly displacement is achieved, when the device stretches into the vagina of a patient, a camera and an atomization spray head are located on the inner sides of four cambered-surface vaginal dilation plates and are in a contraction and storage state, and friction with vaginal mucosa is avoided; the problems that in the using process of an existing device, the vagina of a patient is inconvenient to dilate, the operation difficulty of medical staff is increased, in the process that the device stretches into the body of the patient, a camera and a spray head are always kept in contact with the vagina of the patient, vaginal mucosa discomfort of the patient is easily caused by friction, even slight damage is possibly caused, and the working efficiency is high are solved. Especially for patients with inflammation or mucosal sensitivity, the pain of the patients can be aggravated.
Owner:QINGDAO MUNICIPAL HOSPITAL

Cleaning, nursing and wiping device special for gynecology department

The invention belongs to the technical field of medical instruments, and particularly relates to a cleaning and nursing wiping device special for the gynecology department, which comprises an inserting cylinder, the side wall of the inserting cylinder is of a hollow structure, and a plurality of water spraying holes are formed in the side wall of the inserting cylinder. When the vagina of a patient is flushed, the flushing water pressure is automatically adjusted according to the vagina contraction condition, vagina mucosa damage, pain or discomfort caused by too high water pressure can be effectively avoided, meanwhile, the situation that the treatment effect of thorough cleaning cannot be achieved due to too low water pressure is prevented, and the vagina flushing device can adapt to individual physiological status differences of the patient and can also be used for flushing the vagina. The safety and comfort in the flushing process can be improved, the accuracy and effectiveness of flushing operation can be guaranteed, the tedious process of manual adjustment of medical staff is reduced, the overall efficiency of clinical nursing is improved, vagina wiping is carried out after vagina flushing of a patient is finished, residual cleaning liquid and secreta can be removed in time, and the patient is protected against infection. Moist discomfort caused by liquid retention is avoided, and the risk of bacterium breeding and infection is reduced.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Gynecological gel composition as well as preparation method and application thereof

The invention discloses a gynecological gel composition as well as a preparation method and application thereof. The gynecological gel composition is prepared from the following components in percentage by weight: 10%-15% of isomaltooligosacharide, 22%-26% of lactic acid, 22%-26% of glycerol, 2%-6% of xanthan gum and the balance of purified water. The gel disclosed by the invention has a physical barrier effect: after the gel is dissolved in the vagina, the gel is attached to the surface of vaginal mucosa to form a protective film, so that a wound surface is isolated, secondary cross infection is avoided, repair and regeneration of erosive tissues are accelerated, and healing is promoted. Meanwhile, a layer of protective gel film can be formed on the vaginal wall, so that the vaginal wall is physically isolated from external bacteria, and pathogenic microorganisms are prevented from colonization.
Owner:SICHUAN KEXIN BIOTECHNOLOGY CO LTD