144 results about "Vaginal mucosa" patented technology

Compositions comprising oligosaccharide aldonic acids are useful for general care, as well as for treatment and prevention, of various cosmetic conditions and dermatological disorders, including those associated with intrinsic and/or extrinsic aging, as well as with changes or damage caused by extrinsic factors; general care, as well as treatment and prevention of diseases and conditions, of the oral, and vaginal mucosa; for general oral care, as well as treatment and prevention of oral and gum diseases; and for wound healing of the skin. Compositions comprising oligosaccharide aldonic acids may further comprise a cosmetic, pharmaceutical or other topical agent to enhance or create synergetic effects.

Bioadhesive films for delivery of active agent to the mucosa are disclosed. Particularly, bioadhesive films for treating the vaginal mucosa are disclosed.

A dual adhesive layer dosage form for delivery of active agent to and across, the mucosa is disclosed. Particularly, bioadhesive tablets for administration at the vaginal mucosa are disclosed as having a central active layer sandwiched between two bioadhesive layers.

Modified release oil in water emulsions that delivers drugs to a target tissue. The emulsions according to the present invention contain the lipophilic active ingredient completely dissolved into the hydrophobic internal phase stabilised by a polymeric surfactant. The presence of this polymer around the hydrophobic droplets avoids the migration of the active ingredient into the external hydrophilic phase and, consequently, its re-crystallization.

The invention provides a naturally occurring strain of Lactobacillus crispatus with advantageous characteristics. The strain colonizes mucosal surfaces, particularly vaginal surfaces. The strain is also capable of rapid growth in a number of conditions and is highly viable after desiccation. Moreover, the strain is capable of preventing and reducing pathogenic infection of vaginal mucosa.

The invention belongs to the technical field of medicines and discloses an itraconazole temperature-sensitive type gel preparation as well as a preparation method and application thereof. The itraconazole temperature-sensitive type gel preparation is composed of the following components in percentage by weight: 0.02-3% of medicines, 0.05-15% of solubilizing agent, 5-50% of gel matrix, 0-15% of biological adhesive, 0.001-2% of preservative, 0-10% of other additives and the balance of solvent. The itraconazole temperature-sensitive type gel preparation can regulate gelatinization temperature by adjusting composition and control drug release rate and degree, can effectively inhibit growth of candida in vitro and can be used for drug administration on skins, eyes, nasal cavity, oral cavity, straight intestine or vaginal mucosa. The itraconazole temperature-sensitive type gel preparation has obvious slow release and biological adhesion property and can prolong action time of medicines on an infection part, realize long-acting treatment, reduce dosage and toxic and side effects and improve patient compliance.

Compositions comprising oligosaccharide aldonic acids are useful for general care, as well as for treatment and prevention, of various cosmetic conditions and dermatological disorders, including those associated with intrinsic and/or extrinsic aging, as well as with changes or damage caused by extrinsic factors; general care, as well as treatment and prevention of diseases and conditions, of the oral, and vaginal mucosa; for general oral care, as well as treatment and prevention of oral and gum diseases; and for wound healing of the skin. Compositions comprising oligosaccharide aldonic acids may further comprise a cosmetic, pharmaceutical or other topical agent to enhance or create synergetic effects.

The present invention relates to applicators for applying powders to the vaginal mucosa.

A vaginal treatment composition that rapidly forms a gel when placed into contact with monovalent or polyvalent cations, such as sodium (Na⁺) and calcium (Ca²⁺) cations naturally found in vaginal mucosa, is provided. The gel may form in less than about 1 hour, in some embodiments less than about 1 minute, and in some embodiments, less than about 30 seconds. Among other things, such rapid gelation reduces the likelihood of leakage during use. In addition, because the gel may form intravaginally, it is more likely to retain its structure and shape over an extended period of time. In this manner, the gel may provide the prolonged release of a therapeutic agent that inhibits and/or treats vaginal infection. For instance, the gel may remain within the vagina for about 2 to about 48 hours to provide the desired effect.

A hydrophilic liquid disinfectant for surgical operation, trauma, burn, perineal mucosa, oral mucosa, vaginal mucosa, etc is prepared through adding iodine, chlorhexidine and polyhexamthylene guanidine to non-ionic surfactant, heating, stirring, adding penetrant, phosphoric acid and water, and stirring.

The invention relates to a bacterium and disease prevention wet wipe liquid medicament and a preparation method thereof. The active ingredients of the wet wipe liquid medicament comprise the following components in part by weight: 0.1 to 5 parts of atractylis oil, 0.01 to 0.5 part of berberine, 0.01 to 0.5 part of eucalyptus oil, 0.01 to 0.05 part of borneol, and 0.01 to 0.5 part of menthol. Experiments show that the wet wipe provided by the invention has bacterium and disease prevention functions, no irritation or side effect to skins and vaginal mucosa, aromatic scent, and better effects than the prior art, and is convenient to carry.

The invention relates to the technical field of preparation of colpitis medicines, and especially relates to a vaginal gel and a preparation method thereof in order to solve the technical problem of unsatisfactory bacteriostasis, lubrication and moisture retention effects of existing vaginal gel products. The vaginal gel mainly comprises sodium hyaluronate, vitamin E succinate modified hyaluronic acid, EGF (epidermal growth factors), vitamins C, calcium chloride, pentanediol, glycerin, Rhodicare and a buffer system adopting disodium hydrogen phosphate-citric acid as gel. The vaginal gel has anti-inflammatory activity, improves the wetness of vaginas, is used for treating vaginal inflammatory diseases and alleviating vaginal dryness or used as a human body lubricant, has a vaginal mucosa squamous cell layer restoration promoting effect, can improve vaginal mucosa layer thinning and restore small injuries in vaginas to recover the elasticity and the softness of the vaginal mucosa, and is suitable for colpitis and vagina dryness people.

The invention provides a vagina health probiotic composition. The vagina health probiotic composition comprises lactobacillus plantarum L-137 and at least one female probiotic, wherein the female probiotic is lactobacillus separated from the vagina or the urethra of a healthy female. The inactivated lactobacillus plantarum L-137 has the effect of promoting the growth of probiotics, especially thegrowth of the lactobacillus. The composition disclosed by the invention can recover vaginal flora, so that proliferation of harmful bacteria is inhibited, discomfort such as vaginal pain and itching and dryness can be relieved, peculiar smell is removed, the pH value is balanced, and the immune defense function of vaginal mucosa is enhanced. Vaginitis can be treated in an auxiliary manner; and thevaginitis can be prevented from happening and relapsing.

The invention discloses antibacterial gel for gynecology and a preparation method thereof. The antibacterial gel is prepared from the following raw materials in percentage by weight: 1-5% of cecropinantibacterial peptide, 1-5% of gastrodia elata polypeptide, 1-5% of luteolin, 10-30% of a thickener, 2-6% of a wetting agent, 1-5% of tocopherol, 1-3% of sodium hyaluronate, 0.5-2% of menthol, a proper amount of a pH regulator and the balance of purified water. The antibacterial gel for the gynecology uses cecropin B and gastrodia elata polypeptide as antibacterial peptide active ingredients, which has a synergistic antibacterial effect, and can treat gynecological diseases such as cervical erosion, vaginitis and pelvic inflammation. The antibacterial gel disclosed by the invention is non-irritant to vaginal mucosa cells, high in safety, and excellent in stability and easy to absorb by a human body, and after the gynecological antibacterial gel is used, the skin of the private parts of women can be moisturized, fresh and healthy.

The invention relates to the technical field of preparation of medicines for treating vaginitis, particularly relates to a vaginal gel containing multi-effect factors and a preparation method thereof,and solves the technical problems that the antibacterial, lubricating and moisturizing effects of the existing vaginal gel products are not ideal. The vaginal gel contains a conditioned medium extracting solution of mesenchymal stem cells and traditional Chinese medicine extract, can effectively inhibit the propagation of vaginitis-related bacteria and improve the vaginal moistness, is used for treating vaginal inflammation and relieving vaginal dry symptoms or serves as a human body lubricant, simultaneously has the effect of promoting the repair of the squamous epithelial cell layer of thevaginal mucosa, can enable the vaginal mucosa layer to be thinned and repair small injuries in the vagina, can recover the elasticity of the vaginal mucosa and enable the vaginal mucosa to restore elasticity and softness, and is suitable for people suffering from vaginitis and colpoxerosis.

The invention belongs to the field of sanitary napkins and health pads, and in particular relates to a microbial bacteria powder additive for the sanitary napkins and the health pads, and a preparation method of the microbial bacteria powder additive. The microbial bacteria powder additive is prepared from the following components in parts by weight: 1-4% of lactobacillus acidophilus (CGMCC1.1854), 1-4% of enterococcus faecium (CICC6049), 1-4% of lactobacillus delbrueckii (ACCC11017), 1-4% of lactobacillus helveticus (CICC6024), 1-4% of lactobacillus fermentum (CGMCC1.2133), 1-4% of lactobacillus plantarum (CICC1.2158) and 1-4% of lactococcus lactis (ACCC1.2472). The microbial bacteria powder additive is capable of generating lactic acid, maintaining an acid environment, resisting the invasion of pathogenic bacteria such as mould, escherichia coli and staphylococcus aureus by means of mechanisms such as adhesion competition and vaginal mucosa immunity enhancement, and maintaining vaginal microhabitat balance, thus effectively preventing and treating vagina inflammatory diseases.

The invention discloses a disinfecting and sterilizing fomulation for vaginal mucosa, which comprises Cydiodini, diluent, crumbling agent, acid forming agent, and binding agent. The invention can be applied for effectively eradicate various microorganisms with stable physical and chemical property but no irritating action.

The invention relates to a method for using polygala root to kill sperm externally, wherein it uses polygala root as the drug to kill sperm externally, makes extractive into emulsion or suppositorium, to be used in vagina contraceptive. And its production comprises that: breaking polygala root, immerges in 0.9% normal saline, while their ration is 100g:900-1200ml, to be heated in 100Deg. C metal bath; taking out, filtering out the slag. The inventive polygala root extractive has non stimulation on vaginal mucosa, without damage on vaginal bacterial and side effect. And it has low cost.