The invention relates to Zhuyan medicinal liquor which has the effects of enriching yin, nourishing kidney, strengthening yang, adjusting internal secretion, nourishing gonad and ovary, tranquilizing mind by nourishing heart, tonifying brain, warming kidney, strengthening tendons and bones, relaxing bowels, enhancing immunity of organism and the like and aims at overcoming the defects that the existing medicinal liquor does not have the efficacies of tranquilizing mind by nourishing heart, tonifying brain, delaying climacteric, relaxing bowels and the like. The Zhuyan medicinal liquor has multiple efficacies and a good treatment effect and can be used for treating insomnia and dreamful sleep, habitual constipation, sexual apathy and vaginal dryness during intercourse, delaying the climacteric, recovering the sexual function to realize intercourse after being taken by old people, enhancing memory, preventing encephalatrophy and senile plaque, improving immunity and auxiliarily treating the cervical or lumbar diseases. According to the technical scheme, 100jin Zhuyan medicinal liquor contains the following components and contents: 200-300g of fructus cnidii, 200-300g of schisandra chinensis, 200-300g of cistanche, 200-300g of ginseng, 200-300g of radix polygonum multiflorum preparata, 200-300g of white poria, 200-300g of rehmannia root, 200-300g of asparagus fern, 100-150g of radix morindae officinalis, 100-150g of ligusticum wallichii, 100-150g of dendrobe, 100-150g of Chinese yam, 100-150g of prepared liquorice root, 100-150g of spina date seed, 150-200g of teasel root, 150-200g of loranthus parasiticus, 150-200g of longan aril and 150-200g of eucommia ulmoides; and all the components are soaked for three months to obtain the Zhuyan medicinal liquor, and the Zhuyan medicinal liquor is used after slag removal.