851 results about "Itching" patented technology

The invention relates to a dissolvable food gel gradient-based swallowing ability dynamic quantification method, which comprises the following steps of: constructing a microstructure unit consisting of an instantaneous surface attachment area and a middle-stage debonding layer in dissolvable food gel, and simulating early-stage sensing delay and middle-stage release response in a swallowing process; different material behavior reactions are generated in the front stage, the middle stage and the rear stage of swallowing by regulating and controlling the hydration diffusion rate, the surface tension and the internal cohesion difference value of the gel, and the gel of each stage corresponds to the set micro-viscosity and release coupling ratio, so that swallowing strategies of different stages are adapted; controllable disintegration temperature-sensing microparticles or traceable microcapsules are partially embedded in the food gel, the food gel is detained in a pharyngeal cavity after being swallowed, and the removal efficiency after swallowing is detected according to migration behaviors within a set time window; after swallowing, the reduction behaviors of the oral cavity, the tongue body and the throat muscle group are monitored, and when the characteristic action of reduction delay, secondary mouth opening, repeated swallowing or pharyngeal itching occurs, it is judged that the swallowing behavior closed loop is interrupted.

The invention relates to the technical field of daily chemical products, in particular to a scalp care composition and application thereof. From the perspective of scalp care, selenium disulfide and piroctone olamine salt are taken as bactericides and compounded with bactericidal and anti-dandruff components to form the organic and integrated anti-dandruff and scalp conditioning composition, and the composition has the effects of removing dandruff, relieving itching, soothing and controlling oil and can effectively relieve the problems of dry dandruff and fungal dandruff. The scalp care composition is added into the shampoo, serves as a main component of the multi-effect repairing and dandruff removing shampoo, can effectively solve the problems of oily dandruff, dry dandruff, scalp itching, scalp hair greasy, scalp sub-health and the like, and has the effects of reducing scalp inflammatory response, promoting updating of scalp cutin, inhibiting generation of scalp redundant sebum and the like; the nursing dimension is more comprehensive, and the application range is wider.

The invention provides a Chinese arborvitae twig and folium artemisiae argyi lotion and a preparation method and application thereof, and relates to the technical field of alopecia prevention, the Chinese arborvitae twig and folium artemisiae argyi lotion is prepared from the following traditional Chinese medicines: Chinese arborvitae twig, rhizoma drynariae, folium artemisiae argyi, chrysanthemum, mint, schizonepeta, divaricate saposhnikovia root, ligusticum, wrinkled gianthyssop herb, rhizoma nardostachyos, fructus viticis, radix polygoni multiflori preparata and garden balsam stem, and the Chinese arborvitae twig and folium artemisiae argyi lotion is prepared by soaking and decocting the traditional Chinese medicines in distilled water and filtering out traditional According to the prepared folium artemisiae argyi lotion, the medicinal materials are reasonably matched, the traditional Chinese medicinal materials are combined together according to the compatibility of monarch, minister, assistant and guide, the effects of stimulating hair follicle conversion, inhibiting the activity of 5-alpha reductase, adjusting the scalp microenvironment, relieving scalp greasiness and the like are achieved, heat clearing, dampness eliminating, liver and kidney nourishing and blood cooling and nourishing can be achieved, meanwhile, blood circulation promoting and collateral dredging can be achieved, and the effect of removing blood stasis is achieved. The traditional Chinese medicine composition has a good effect on androgen alopecia, alopecia areata, scalp seborrheic dermatitis or scalp psoriasis with symptoms such as alopecia, more oily hair, scalp desquamation or itching and the like.

The invention relates to the technical field of cosmetics, and discloses an anti-inflammatory soothing cosmetic composition which comprises the following components in percentage by weight: 0.5%-4% of a barrier repairing component, 0.5%-3% of an immunoregulation component, 0.3%-2.5% of a nerve soothing component, 0.3%-3% of an anti-inflammatory plant compound, 1%-10% of a moisturizing soothing enhancer and the balance of auxiliary materials. According to the components, through a five-dimensional synergistic mechanism of barrier repair, immune tolerance, nerve desensitization, anti-inflammatory itching relieving, moisturizing and stability maintaining, anti-inflammatory relieving and barrier repair are remarkably enhanced; ceramide, rare ginsenoside, phytosterol ester and free fatty acid are introduced to synergistically construct a bionic liposome which is closer to the composition of human cuticle lipid, so that the transdermal absorption and stability are enhanced, and the repair efficiency is remarkably improved; the dipotassium glycyrrhizinate, the tamarix chinensis flower extract, the purslane extract, the dinoflaxanthine and the baicalin cooperate to quickly resist inflammation and relieve itching and strengthen barrier repair, so that the composition is suitable for highly sensitive skin.

The invention discloses medical soap for sterilizing, relieving itching and removing acne and a manufacturing method thereof, belonging to the field of articles of everyday use. The medical soap is prepared from ingredient A, ingredient B and ingredient C, wherein the ingredient A is prepared from dandelions, folium isatidis, rabdosia rubescens and glabrous sarcandra herb; the ingredient B is prepared from radix angelicae, rhizoma typhonii, white poria, Chinese angelia root tai, radix pseudostellariae, raw milkvetch root, Chinese honeylocust fruit, red paeony root, prepared kusnezoff monkshood root, radices lithospermi, cortex dictamni, thunberg fritillary bulb, fiveleaf akebia fruit, white muscardine silkworms and solanum lyratum; the ingredient C is prepared from soap base, honey and bovine bone marrow oil. The medical soap disclosed by the invention is used for external washing or smearing after being wet by adding water in the morning and evening every day; after a person with smelly feet washes the feet, the medical soap is smeared in gaps between toes; and the medical soap is not suitable for use when the skin is damaged. The medical soap prepared by the invention is a black brown solid body, and has soap medicine odor; the medical soap can be used for nourishing the skin, is antiallergic, beautifies the features, removes acne, relieves itching, removes freckles, clearing heat and deterring sweat; the medical soap can beautify the features, whiten the skin, and remove the acne and the freckles when used for washing the face, and can deter the sweat, remove the smelly odor and treat dermatophytosis when used for washing the feet; and the medical soap has a control effect on the itching toxin which appears after mosquito bite, and has a moisturizing effect for the person having the dry skin.

The invention discloses an external traditional Chinese medicine mixture aiming at genital skin mucosa ulceration wound repair and a preparation method thereof, relates to the field of traditional Chinese medicines, and aims to provide a genital skin mucosa ulceration wound repair medicine which has the effects of promoting wound repair and relieving itching, and is simple in component, small in allergy probability, light and thin in dosage form and good in skin feeling. The traditional Chinese medicine mixture is prepared from chicken butter, honeysuckle stem, felwort, cortex dictamni, fructus kochiae, radix scutellariae, cortex phellodendri, angelica sinensis, radix rehmanniae, radix arnebiae seu lithospermi, sanguisorba officinalis and bletilla striata. The traditional Chinese medicine mixture disclosed by the invention realizes simultaneous treatment of pruritus vulvae and ulceration, fills the treatment blank, relieves symptoms as soon as possible, shortens the treatment cycle and saves expenditure. The curative effect is prominent, and current clinical requirements are met. Cost and loss are reduced. Preparation is convenient, high-end machines are not needed, and preparation can be carried out at home.

The invention discloses a barrier repair composition applicable to dry sensitive skin and application thereof. The composition comprises a golden camellia extract, a loquat leaf extract, an alfalfa extract and hydrolyzed royal jelly protein. According to the barrier repairing composition applicable to the dry sensitive skin, disclosed by the invention, through reasonable matching and synergistic interaction of all the components, a better skin barrier repairing effect can be achieved, so that the problems of dry and tight skin, desquamation, erythema, itching, dull luster, redness, burning heat sensation, pricking pain and the like of the dry sensitive skin are fundamentally solved.

The present invention discloses an adjustable and modifiable garment for the treatment of sensory and neuro-divergency conditions that can treat a significant number of issues for different wearers with discretion from possibly judgmental third parties. The invention combines a hoodie with drawstrings, torso covering, compression sleeves, thumb holes, pocket, hem band with adjustable elements, and fidget toy attachments. The invention is comprised of a hoodie with weighted insert panels of variable weights, adjustment mechanisms for the compression or tightness of the garment; food-grade silicone coated hoodie strings for safe chewing; a hood rise used as a face covering; flat felled, serged, and fully lined seams to prevent irritation; thumbholes for additional comfort and grip; invisible seams to hide weighted panel inserts; hidden silicone beads for fidgeting inside the front pocket; and heat transfer labels (replacing scratchy tags sewn into garments) to prevent itching and provide comfort to the wearer.

The invention relates to the technical field of daily chemicals, in particular to a dark tea extract containing eurotium cristatum composite strains for solid aerobic fermentation. The composite strains comprise eurotium cristatum and saccharomycetes. The dark tea extract provided by the invention is stable in performance and not easy to discolor, contains components such as polysaccharide, amino acid and mineral substances, and can help skin moisturize. The permeability of the components is enhanced in the fermentation process, moisture can be locked on the surface layer of the skin, and the moisture degree of the skin is kept. The skin care product has very strong antioxidant capacity, and can neutralize free radicals, slow down the oxidation process of skin, delay skin aging and reduce wrinkles and fine wrinkles. A certain calming effect can be achieved on the skin which is prone to redness and itching or has slight inflammation.

The invention belongs to the technical field of microorganisms, and particularly relates to an extracellular vesicle of phytobacterium plantarum and application of the extracellular vesicle. Specifically, the plant lactobacillus extracellular vesicles can promote HaCaT cells to generate ceramide, up-regulate expression of key genes in a skin ceramide synthesis route and recover a skin barrier; the expression of proinflammatory factors in a cell inflammation model can be reduced, and a relatively good anti-inflammatory effect is achieved. A mouse skin injury model verifies that the EVs has good skin infiltration capacity and can remarkably reduce the skin injury score, relieve skin itch, improve the skin water content and reduce expression of proinflammatory factors in skin tissue and expression of pruritus-related cell factors.

The invention discloses a composition for regulating scalp micro-ecology and application thereof, and relates to the technical field of daily chemical products. The composition for regulating scalp micro-ecology comprises the following components: emu oil, melaleuca alternifolia leaf oil, Brazil green propolis and hydrogenated castor oil. The invention provides a composition for regulating scalp microecology and application thereof, the composition is prepared by compounding an anti-inflammatory and antibacterial component emu oil with melaleuca alternifolia leaf oil, Brazilian green propolis and hydrogenated castor oil, the composition has synergistic bacteriostasis and anti-inflammation effects, keeps scalp microbe balance, reduces red and swollen skin and itching, and also can promote the regeneration capacity of skin tissue cells.

The invention relates to an itching relieving and soothing skin care lotion and a preparation method thereof. The skin care lotion is prepared from the following raw materials in parts by weight: 10-20 parts of grease, 1-3 parts of a nonionic emulsifier, 0.1-1 part of a skin feeling regulator, 0.5-2 parts of a first skin conditioner, 1-5 parts of a second skin conditioner, 0.1-1 part of an antioxidant, 1-2 parts of a humectant, 0.1-1 part of a pH regulator and 70-85 parts of water, the first skin conditioner contains a citrus peel extract and carboxymethyl chitosan, and the second skin conditioner contains hydroxyphenyl propionamide benzoic acid, stearyl glycyrrhetinate, menthol lactate, alpha-bisabolol and guaiazulene. The skin care lotion does not contain diphenhydramine hydrochloride and other substances with safety risks, is safe and mild, has remarkable itching relieving and soothing effects, and is safe and non-irritant to infants and children; during preparation, heating is little, and the activity of active substances can be reserved to the maximum extent so as to effectively ensure the itching relieving and relieving effects of the product.

The invention relates to the field of daily chemicals, and discloses selenium disulfide anti-dandruff and itching-relieving shampoo and a preparation method thereof, and the selenium disulfide anti-dandruff and itching-relieving shampoo comprises selenium disulfide, glycerin, mud, water and other materials. The problems that in the prior art, mild oil control is difficult, sensitivity is avoided and the like are solved, the shampoo prepared by matching a sulfate-free mild detergent with anti-dandruff and itching-relieving components such as selenium disulfide can remove redundant grease and dandruff on the scalp and improve the micro-ecological environment of the scalp, and the long-acting oil control, anti-dandruff and refreshing effects are achieved.

The present invention belongs to the technical field of medical catheters, and in particular, relates to a catheter care and fixing device for intravenous treatment, including an arm sleeve, a catheter guide clamping mechanism is fixedly installed on the upper end of the arm sleeve, a pressurizing fixing mechanism is fixedly installed on the arm sleeve, and a pressurizing confirmation mechanism connected to the pressurizing fixing mechanism is also fixedly installed on the outer wall of the arm sleeve. The present invention can prevent the catheter from being pulled and causing the catheter to move, thereby causing a greater impact on the patient, and can perform ventilation and dehumidification work at intervals between the arm sleeve and the patient's arm to avoid the arm sleeve pressing on the outside of the patient's arm, which will cause excessive sweat secretion on the skin, thereby causing skin redness, itching and eczema. It can automatically adjust the interval time of ventilation and dehumidification based on the thickness of the patient's arm, so as to meet the needs of patients with thicker arms to use higher frequency ventilation and dehumidification work.

The invention discloses a plant-sourced anti-allergy soothing composition and application thereof, and belongs to the field of cosmetic processing.The plant-sourced anti-allergy soothing composition is prepared from hydrolyzed corn starch, saururus chinensis extract, carrot root extract and water-soluble hesperidin. Active ingredients of plant sources are deeply studied, and the anti-allergy soothing composition has the advantages that the plant-sourced anti-allergy soothing composition is prepared from the hydrolyzed corn starch, the saururus chinensis extract, the carrot root extract and the water-soluble hesperidin; a series of plant extracts with a synergistic effect are screened out, the plant-source multi-dimensional composition for relieving itching and repairing red is successfully researched and developed, and through the synergistic effect of the hydrolyzed corn starch, the saururus chinensis extract, the carrot root extract and the water-soluble hesperidin, the composition has the effects of relieving and repairing skin in a multi-dimensional mode, relieving itching and repairing red. In addition, the composition can repair the skin barrier for a long time and improve the tolerance of the skin, and meanwhile, the composition has good safety and stability and is suitable for various skin types, especially sensitive skin.

The invention discloses an itching-relieving and hair-loss-preventing micro-capsule composition containing a golden camellia extract and a preparation method of the itching-relieving and hair-loss-preventing micro-capsule composition, and relates to the technical field of daily chemical products. The microcapsule mainly comprises a surfactant, palmitoyl tripeptide, ossein amino acid, betaine salicylate, a nano zinc oxide chelate, a plant extract, vegetable oil and a microcapsule component formed by a microcapsule wall material prepared from gelatin and sodium alginate. The plant extract, the plant oil-containing microcapsules, palmitoyl tripeptide, ossein amino acid, betaine salicylic acid, nano-zinc oxide chelate and the like have synergistic interaction, and the plant extract has antioxidant, antibacterial and anti-inflammatory effects and is matched with other components, so that lasting antibacterial effect is enhanced, dandruff can be effectively cleaned and removed, scalp can be repaired, microcirculation of the scalp can be effectively improved, and the scalp care effect can be improved. The scalp itching is reduced, and the alopecia problem is improved.

The invention provides an anti-allergy soothing sanitary towel composite chip containing a purslane component and a preparation method, and belongs to the technical field of sanitary towels. The composite chip is of a multi-layer structure, the middle layer is a water absorption layer, the upper layer is an anti-allergy soothing layer, and the lower layer is a water-resisting layer; the anti-allergy soothing layer is a nanofiber membrane loaded with probiotic microspheres and a purslane extract, and the water-resisting layer is a polyethylene film or a polypropylene film; the water absorption layer is a composite layer of silicon dioxide aerogel and polyurethane sponge. The prepared anti-allergy soothing sanitary towel composite chip containing the purslane component not only has various biological functions of absorption, deodorization, peculiar smell removal, antibiosis, anti-inflammation, anti-allergy soothing, antioxidation, adjustment of ecological balance of private parts and the like, so that the effects of relieving itching and allergy, protecting skin barriers, resisting inflammation and the like are achieved, vaginal flora can be adjusted, and the effects of relieving itching, relieving itching, relieving inflammation and the like are achieved. And vaginitis and the like are reduced, the private health of women in the menstrual period is protected, and the health of women is facilitated.

The invention discloses a conditioning composition for comprehensively controlling oil and repairing scalp and a preparation method thereof. The scalp conditioning composition is prepared from the following components in percentage by mass: 0.5 to 5 percent of a folium nelumbinis NUCIFERA extract, 0.2 to 2 percent of a PHELLODENDRON AMURENSE extract, 0.2 to 2 percent of a radix sophorae flavescentis root extract, 0.1 to 5 percent of a cortex magnoliae officinalis OFFICINALIS bark extract, 0.5 to 8 percent of schizophyllan, 1 to 10 percent of a lactobacillus fermentation lysate and the balance of a conventional cosmetic additive. Wherein the schizophyllan is composed of the schizophyllan with the molecular weight of 6 million to 10 million Daltons and the schizophyllan with the molecular weight of 2000 to 5000 Daltons. According to the invention, plant-derived oil-control antibacterial components are matched with schizophyllan with different molecular weights and the balance of micro-ecological flora is regulated, so that the scalp health problems such as scurf, itching, sensitivity and the like are comprehensively solved from a short period, a long period and the bottom layer of the scalp.

The invention discloses a soothing composition for relieving itching of a body and application of the soothing composition, and relates to the technical field of cosmetics. The invention discloses a soothing and itching relieving composition, which is prepared from the following ingredients in parts by weight: 0.1 to 0.5 part of phoenix dactylifera seeds, 1 to 5 parts of hyperforin perforatum flower extracts, 1 to 10 parts of Brazil nectarine fruit oil and 0.01 to 0.2 part of L-homoserine. Through cooperation of the phoenix dactylifera seeds, the hyperforin perforatum flower extract, the Brazilian nectarine fruit oil and the L-homoserine, on one hand, when the temperature changes and nursing is improper, sensitive skin can be helped to be calm and relaxed, and the resistance of the skin to external environment influence is enhanced; on the other hand, the composition can synergistically moisturize, relieve and reduce skin sensitivity and prevent skin itch and dryness.

The invention belongs to the technical field of daily chemicals, and discloses a vegetable oil and essential oil composition and application thereof. The plant oil and essential oil composition is prepared from the following components in parts by weight: 50 to 80 parts of crambe abyssinica seed oil, 5 to 20 parts of rosa rugosa seed oil, 8 to 15 parts of evening primrose oil, 2 to 15 parts of acanthopanax gracilistylus root and bark extract and 1.2 to 5 parts of jasminum grandiflorum extract. The vegetable oil and essential oil composition is added into massage oil and can go deep into the bottom layer of skin, inhibit generation and release of inflammatory factors, relieve inflammatory response of the skin, relieve symptoms such as red and swollen, pain and itching caused by inflammation, balance grease secretion of the skin, promote blood circulation of the skin and relieve inflammation. The elasticity and luster of the skin are improved, the formation of stains and darkness is reduced, and the skin is brighter and more uniform.

The invention discloses a thermal spring water composition for relieving itching and soothing skin and a preparation method of the thermal spring water composition, and belongs to the technical field of itching relieving and soothing. Chitosan has good film-forming property, after chitosan, mung bean protein and the like form a compound, after the compound is smeared on the surface of skin, a layer of relatively stable protective film with certain air permeability can be constructed, skin allergy and inflammatory reaction can be reduced, a relatively wet microenvironment is formed on the surface of the skin, and the skin care effect is improved. The moisture loss of the skin is reduced, and the moisture balance of the skin is favorably kept, so that uncomfortable symptoms such as dry and tight skin are relieved, and the skin is further promoted to be relieved; after the centella asiatica polysaccharide is subjected to carboxymethylation modification, the water solubility and the biological activity of the centella asiatica polysaccharide are remarkably improved, and the carboxymethylated centella asiatica polysaccharide and the mung bean protein-chitosan compound have a synergistic effect, so that the barrier function of skin can be enhanced, the metabolism of skin cells can be regulated, and the skin can be effectively protected. The repair and regeneration of damaged skin cells are promoted.

The invention relates to a traditional Chinese medicine composition for treating allergic dermatitis. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicines in parts by weight: 5-35 parts of fried coix seeds, 5-35 parts of concha margaritifera, 1-30 parts of honeysuckle stems, 1-30 parts of smoked plums, 1-30 parts of fructus liquidambaris, 1-25 parts of fructus forsythiae, 1-25 parts of radix paeoniae rubra, 1-25 parts of raw sanguisorba officinalis, 1-25 parts of radix glehniae, 1-25 parts of radix ophiopogonis and 1-25 parts of raw radix polygonati officinalis. 1-25 parts by weight of talc and 1-25 parts by weight of lophatherum gracile. The traditional Chinese medicine composition has the effects of clearing heat, cooling blood without bitter cold, dispelling wind, eliminating dampness without hurting stomach, detoxifying, relieving itching and nourishing yin, is safe in clinical use, and has no adverse effect on liver and kidney.

The invention belongs to the technical field of anti-aging products, and particularly relates to an anti-aging composition as well as a preparation method and application thereof. The anti-aging composition is prepared by mixing the following raw materials in percentage by mass: 0.5%-1% of xanthophyll, 0.1%-0.3% of pyrroloquinoline quinone, 0.01%-0.02% of sodium propyl paraben, 0.5%-1% of an emulsifier and the balance of water. The emulsifier is a non-ionic emulsifier. The anti-aging composition prepared by the invention has definite components, is free of allergic reactions such as skin redness, rash and itching through tests of multiple testees, and is milder and significantly reduced in sensitization rate compared with products in the prior art.

The invention provides a composition for relieving chronic skin itching, a preparation method and application, and belongs to the field of daily chemicals. The composition capable of relieving chronic skin itching comprises a water phase, a non-water phase and an emulsifier. The water phase comprises a water-soluble medicinal and edible substance and an active substance phase A, the non-water phase comprises a non-water-soluble medicinal and edible substance and an active substance phase B, and the emulsifier comprises alcohol-soluble protein. The composition comprises multifunctional effective active components with functions of moisturizing, repairing, anti-inflammation and the like, the effective components are coated by the prolamin to form a stable emulsion, and the composition is suitable for various washing and skin care product formulas and can effectively relieve chronic skin itch.

The invention discloses a modified melittin peptide, a product containing the modified melittin peptide and application, and belongs to the technical field of biological medicine. The amino acid sequence of the modified melittin is shown as Seq ID No: 2, the molecular weight of the modified melittin is 3123.5 Da, and the isoelectric point of the modified melittin is 12.64. The invention further discloses application of the modified melittin peptide in preparation of drugs or cosmetics for inhibiting inflammation and relieving skin erythema and itching. The invention also discloses application of the modified melittin peptide in preparation of drugs or cosmetics for enhancing cell activity and promoting tissue repair. The melittin modified peptide can significantly reduce the cytotoxicity of natural melittin and significantly enhance the anti-inflammatory activity and tissue repair activity of the melittin, has no sensitization and phototoxicity, and can provide key technical support for research and development of new-generation efficient and safe anti-inflammatory repair drugs, cosmetic products and related biological materials.

The invention belongs to the field of daily chemicals, and particularly relates to a selenium disulfide stable emulsification system.The preparation method of pre-dispersed selenium disulfide comprises the steps that selenium disulfide, glycerin and polysaccharide are mixed and homogenized, then zwitterionic surfactant is added, and the pre-dispersed selenium disulfide is prepared; the polysaccharide has a thickening function in water. According to the emulsifying system, glycerol and xanthan gum are adopted for pre-dispersing and wrapping selenium disulfide, so that selenium disulfide can be suspended by sorbitan triisostearate with three hydrophobic groups, after the formula is used, the selectivity of an emulsifying agent in the emulsion is wider, and meanwhile, the emulsifying effect is better. In a formula development process, sorbitan triisostearate is found to have very good moistening and moisturizing effects on scalp, and the problems of dandruff increase and head itching caused by using selenium disulfide shampoo by a dry scalp user can be solved by using sorbitan triisostearate. Meanwhile, the invention further provides application of the emulsification system and shampoo.

The invention belongs to the technical field of external preparations, and provides compound itching-relieving cream as well as a preparation method and application thereof. The compound itching-relieving ointment is prepared from the following components in parts by weight: 3 to 6 parts of rhizoma coptidis, 9 to 15 parts of radix scutellariae, 9 to 15 parts of radix et rhizoma rhei, 3 to 6 parts of herba schizonepetae, 3 to 6 parts of herba menthae, 1 to 3 parts of cortex moutan, 1 to 3 parts of sandalwood and 0.5 to 1 part of borneol. The compound antipruritic ointment has the effects of cooling, relieving itching, detoxifying and diminishing swelling, and is used for treating itching and eczema dermatitis itching caused by biting of various small insects such as mosquitoes and the like. According to the compound antipruritic ointment disclosed by the invention, a plurality of components are in synergistic interaction, so that a multi-target and multi-layer treatment effect is realized. The traditional Chinese medicine composition can be used for cooling, relieving itching, detoxifying and diminishing swelling from the source while quickly relieving itching, and a comprehensive and effective solution is provided for itching.

The invention provides a polypeptide and application thereof in preparation of a TRPV1 inhibitor, and particularly belongs to the technical field of biomedicine. The invention provides a polypeptide which is named as Cath2, and the amino acid sequence of the polypeptide is as shown in SEQ ID NO. 1. The Cath2 can significantly inhibit activation of a TRPV1 ion channel of a mammal, inhibits TRPV1 receptors of other species including human beings in a targeted manner, and can be applied to research of TRPV1-related ion channel diseases and development of drugs. Specifically, the composition can enhance the resistance of mammals to pruritus and pain, can be used as a resource to be developed into an itching relieving product or an analgesic product and the like, and is applied to human beings and other animals to relieve pruritus and pain.

A lower body garment is disclosed having a sling assembly for securing male genitalia. The sling assembly is configured with limited, prescribed attachment points, which enables increased comfort and support, for the wearer. Moreover, the sling assembly provides a comfortable encapsulation that reduces the jostling of the testicles during athletic endeavors. The sling assembly configuration can further provide moisture management to reduce itching, chafing, and infection.

The invention discloses an anti-inflammatory, antibacterial, itching-relieving and skin-moistening compound composition and a preparation method thereof, and relates to the field of medicines. Comprising the following components in parts by weight: 0.5-2 parts of chlorhexidine acetate, 5-15 parts of radix sophorae flavescentis, 2-8 parts of Chinese prickly ash, 3-10 parts of folium artemisiae argyi, 4-12 parts of cortex phellodendri, 2-6 parts of cortex pseudolaricis, 3-9 parts of fructus kochiae, 1-5 parts of cortex dictamni, 1-4 parts of rhizoma atractylodis, 1-4 parts of radix saposhnikoviae, 2-6 parts of fructus cnidii, 1-5 parts of radix cynanchi paniculati, 0.5-2 parts of borneol, 5-15 parts of aloe and 10-30 parts of propylene glycol. 5-15 parts of tea oil and 1-5 parts of herba violae; according to the anti-inflammatory, antibacterial, itching-relieving and skin-moistening compound composition and the preparation method thereof, various Chinese herbal medicine components are carefully screened and scientifically proportioned, so that the compound composition can remarkably inhibit growth of bacteria and fungi and effectively relieve skin inflammation response, and meanwhile, the excellent itching-relieving and skin-moistening effects are shown.