The invention relates to a pharmaceutical composition which is a pure Chinese medicine composition used for treating beriberi, tinea pedis, smelly feet or sweaty feet. The pharmaceutical composition formula comprises dried alum, sophora flavescens, phellodendron and sulphur which have functions of desinsection and relieving itching, safflower, menispermaceae, dahurian angelica root, betel nut, rhizoma atractylodis which have functions of quickening blood, dispelling stasis and eliminating dampness, clove bud, seatung bark, Chinese prickly ash which have functions of removing peculiar smell and astriction. In the pharmaceutical composition, all medicines are compatible, bring out the best in each other, and have an obvious curative effect for treating hundreds of people which is worth for being popularized, A clinical experiment shows that the pharmaceutical composition has substantial treatment effects on beriberi, tinea pedis, smelly feet or sweaty feet, and has certain curative effect on numbness of the lower limbs and foot caused by rheumatism, the pharmaceutical composition for treating beriberi, tinea pedis, smelly feet or sweaty feet has no toxicity and side effect and is suitable to people of all ages.