The invention relates to a medicine for curing eumycete dermatosis and the preparation method. The medicine is made through the following steps: the japanese intensity scale maple, stemona root, selinum, broom cypress fruits, chaulmoogra, pseudolarix, sophora flavescens, sulfur, hernquecksilvea and amphor together are mixed according to weight proportion, then the mixture is immersed in acetic acid and filtered, and put in bottols finally. Through clinical verification and use, the invention has the functions of eliminating dampness and relieving itching, disinsection and curing eczema, which can be applied externally on the affected part, and mainly cures various eczemas, tetter, smelly feet and hyperhidrosis, with noticeable efficacy on various chronic eczemas. The invention has the advantages of simple manufacturing process, convenient use and noticeable efficacy.