33 results about "Hyperpigmentation" patented technology

The invention relates to a light loss repairing composition for improving skin resistance and application of the light loss repairing composition, and belongs to the technical field of cosmetics. The light loss repairing composition for improving the self resistance of the skin comprises the nannochloropsis oculata extract, the butterflybush flower extract and the bisabolol, all the components have a synergistic effect, ultraviolet light and blue light can be protected, and the light loss repairing composition has an anti-light aging effect and can be used for repairing the self resistance of the skin. And the mask has the effects of repairing skin barrier, relieving skin inflammation, improving redness, preventing hyperpigmentation, resisting aging, tightening skin, improving skin state and the like, and has the effect of improving self resistance of the skin.

The peptides of the present invention exhibit skin whitening activity by inhibiting melanin synthesis in melanocytes and inhibiting melanin body migration. Therefore, the peptide of the present invention can be used as an active ingredient in a medicament for treating or preventing hyperpigmentation diseases caused by excessive deposition of melanin bodies, or as an active ingredient in a cosmetic for skin whitening.

The invention provides a red rice / mung bean fermentation mud film and a preparation method thereof.The preparation method comprises the steps that 1, red rice is weighed, a proper amount of water is added, or soaked mung beans are weighed, and after high-temperature sterilization, the mung beans are cooled to the room temperature, and a substrate is obtained; step 2, inoculating a schizophyllum commune seed solution or a lucid ganoderma seed solution into the substrate, and standing for fermentation culture to obtain a fermented product; and step 3, adding water into the fermented product, and sequentially carrying out homogenization, grinding, sterilization and preservative treatment to finally obtain the red rice / mung bean fermented mud film. According to the method, the red rice or mung bean fermentation product can be effectively utilized, the moisture retention performance and sensory comfort of the product are remarkably improved while the mud mask is endowed with strong cleaning power, and various mineral raw materials can be replaced or partially replaced to prepare the mud mask. Especially, the red rice fermented mud film has extremely strong immediate oil control performance and purification effect, good moisturizing and moisturizing effects, no irritation to skin melanocytes, no pigmentation after inflammation, and good skin smoothing effect.

The peptides of the present invention exhibit skin whitening activity by inhibiting melanin body uptake in keratinocytes. The peptide of the present invention can be used as an active ingredient in a medicament for treating or preventing hyperpigmentation diseases caused by excessive deposition of melanin bodies, or as an active ingredient in a cosmetic for skin whitening.

The peptide of the present application has a skin-whitening activity by inhibiting incorporation of melanin into keratinocytes and promoting degradation of melanin. The peptide of the present application can be used as an active ingredient in a medicament for treating or preventing a hyperpigmentation disease caused by excessive deposition of melanin, or as an active ingredient in a cosmetic for skin whitening.

Provided are compositions and methods for decreasing hyperpigmentation of a subject in need thereof. In some embodiments, the methods comprise administering a composition comprising a compound having a structure of Formulas (I) or (II), or a salt thereof.

The peptides of the present invention exhibit skin-whitening activity by inhibiting the absorption of melanosomes in keratinocytes. Therefore, the peptides of the present invention can be used as active ingredients in medicaments for treating or preventing hyperpigmentation caused by excessive melanosome deposition, or as active ingredients in cosmetics for skin whitening.

The invention belongs to the technical field of cosmetics, and particularly relates to an anti-aging repairing composition and a cosmetic. The anti-aging repairing composition comprises needle-like silica and a nucleic acid tetrahedron solution. According to the composition and the cosmetic, controlled skin injury is formed through the needle-like silica, skin pore blockage is relieved, natural stripping of aged cuticle is accelerated, microcirculation of skin cells below the cuticle is activated, the overall metabolic condition of epidermis is improved, a natural skin repairing mechanism is stimulated, and under the synergistic effect of tFNA, the skin can be effectively repaired. Synthesis of important construction substances such as collagen, elastin and hyaluronic acid is promoted, the skin barrier function is repaired, and the skin health state is improved. Therefore, various skin defects such as skin photoaging, roughness, relaxation, wrinkles, dryness, hyperpigmentation, sensitivity and angiotelectasis are remarkably improved.

A dual-surfaced exfoliating and cleansing cloth is disclosed, comprising a first side formed of knotted nylon mesh with raised, interlocking knots configured to exfoliate the skin through rolling friction, and a second side formed of a soft, absorbent fabric such as a bamboo-cotton blend or microfiber textile for gentle cleansing. The cloth may be reusable, machine-washable, quick-drying, and resistant to microbial growth. It can be used to treat common skin conditions including acne, keratosis pilaris, and hyperpigmentation by combining effective exfoliation with skin-safe cleansing in a single article. A corresponding method of manufacturing the cloth is also disclosed, involving the formation of a uniform knotted nylon mesh and integration with a soft textile layer.

This invention provides a topical ointment containing Yunnan white pearl powder, its preparation method, and its application, belonging to the field of traditional Chinese medicine. By incorporating myrrh extract, scutellaria baicalensis extract, and ceramides, the synergistic effect of these active ingredients not only achieves the basic effects of anti-inflammatory, antibacterial, and skin barrier repair, but also unexpectedly enhances the transdermal absorption rate of Yunnan white pearl powder essential oil, strengthens its anti-inflammatory effect, reduces irritation, and extends its shelf life. Furthermore, it can inhibit post-inflammatory hyperpigmentation, with effects far exceeding the combined efficacy of individual ingredients and conventional compound formulations.

The present invention provides compositions and methods for orally and / or topically treating skin diseases and conditions, such as acne, atopic dermatitis, psoriasis, facial redness, folliculitis, dry skin, itchy skin, hyperpigmentation, aging, wrinkles, etc., by administering to a subject in need thereof a pharmaceutical composition or dietary supplement comprising an in vitro grown grape cell line culture. Additionally, the present invention provides methods and compositions for treating skin conditions and diseases, such as acne, atopic dermatitis, psoriasis, facial redness, folliculitis, dry skin, itchy skin, aging, wrinkles, etc., by topically administering to a subject in need thereof a pharmaceutical composition or cosmetic composition comprising an in vitro grown grape cell line culture.

Disclosed in certain embodiments herein is a topical formulation including a tyrosine inhibitor, a skin brightener, and a resorcinol compound. The topical formulation does not include hydroquinone to comply with new federal regulations. A delivery system and method of treating hyperpigmentation is also provided.

This provides a new treatment for hyperpigmentation, a skin condition characterized by decreased pigmentation. [Solution] In one aspect, the present invention relates to a topical composition for the treatment of depigmentation skin diseases, comprising staurosporine or a pharmaceutically acceptable salt thereof as an active ingredient.

Disclosed herein are cosmetic compositions. More particularly, disclosed herein are cosmetic compositions comprising ubiquinone, and at least one skin care benefit agent selected from acetyl methionine, a salt thereof or combinations thereof for combating the harmful effects of atmospheric pollution relating to hyperpigmentation in human skin.

The present invention relates to the use of botulinum toxins for the treatment of hyperpigmentation conditions. The use includes intracutaneously injecting botulinum toxin into the skin of a patient with hyperpigmentation at a specific depth, volume and dose to specifically target the epidermal layer and the upper dermal layer. For example, an intradermal injection of botulinum toxin according to the invention may be used to treat chloasma.

Disclosed herein is a method for improving the appearance of blemish skin comprising applying to the skin a composition comprising a German chamomile essence component as an active ingredient and a physiologically acceptable carrier. In one embodiment, the method involves reducing comedo, sebum secretion, pore oversize, post-acne scars and expression lines, improving skin barrier function, and improving complexion by reducing redness, hyperpigmentation and post-acne hyperpigmentation.

The present invention relates to the cosmetic, nutraceutical use of a strain of Lactobacillus crispatus, in particular that filed under number CNCM I-5579, and / or of a composition comprising it, to reduce pigmentation of the skin and / or mucous membranes and / or prevent its increase, in particular to preserve and / or improve the complexion of the skin and / or mucous membranes, preferably to preserve and / or improve the radiance and / or luminosity and / or homogeneity of the complexion of the skin and / or mucous membranes, and / or to prevent the appearance and / or reduce the presence of pigment spots on the skin and / or mucous membranes and / or detoxify the skin and / or mucous membranes.It also concerns the strain of Lactobacillus crispatus, or a dermatological composition comprising it, for its use, advantageously by topical route, for the treatment and / or prevention of pathologies of the skin and / or mucous membranes associated with an increase in pigmentation of the skin and / or mucous membranes, in particular to depigment and / or prevent hyperpigmentation of pathological skin and / or pathological mucous membranes.

The utility model discloses a bacteriostatic skin-moistening type nursing wet tissue which comprises an external-pressing edge-covering strip and a multi-layer mechanism, and the external-pressing edge-covering strip is located outside the multi-layer mechanism. According to the anti-bacteria skin-moistening type nursing wet tissue, the wet strength cloth layer, the soft cotton layer and the silky layer are all integrally formed through hot pressing, the soft cotton layer is good in water absorption and water release performance, the silky layer is more close to the skin, the wet strength cloth layer improves moisture absorption, the externally-pressed edge covering strips are located outside a multi-layer mechanism, external edge covering can be enhanced, and the anti-bacteria skin-moistening type nursing wet tissue is good in anti-bacteria effect. The antibacterial, skin moistening and moisturizing effects of the wet tissue are improved through the antibacterial layer, the anti-bacterial layer, the anti-corrosion layer, the moisturizing layer, the soothing and repairing layer and the nutritional layer, the nutritional layer is rich in natural moisturizing factors and reduces hyperpigmentation, so that the skin whitening effect is achieved, the wet strength cloth layer, the cotton soft layer and the silky layer are integrally formed through hot pressing, and the wet strength cloth layer, the cotton soft layer and the silky layer are integrally formed through hot pressing. And the rhombic pressing grids are formed on the surface of the wet strength cloth layer through an embossing roller.

The invention provides a combined application of a ganoderma lucidum extract and ergothioneine in preparation of a product for repairing mitochondrial injury of skin cells. According to the invention, the ganoderma lucidum extract and the ergothioneine in a mass ratio of 1: (0.5-3.5) are combined for use, so that the skin cell mitochondrial injury can be effectively repaired, and the phenomena of skin barrier injury, wrinkle formation, hyperpigmentation and the like caused by the skin cell mitochondrial injury are further improved, that is, aging caused by the skin cell mitochondrial injury is delayed.

The invention provides a cosmetic application of a cyclic polypeptide, the cyclic polypeptide is H-Cys-Tyr-Val-Gln-Arg-Lys-Arg-Gln-Lys-Leu-Met-Pro-Cys-Lys (Met-Pro-D-Ph-Arg-D-Trp-Ph-Lys-Pro-Val-PEG5CH2CO)-NH2 (1, 13 disulfide bond cyclization), and the cyclic polypeptide is used for preparing a cosmetic skin care product which is used for breaking sensitive circulation and controlling hyperpigmentation and has the effects of resisting allergy and whitening at the same time. The cyclic polypeptide is prepared into a product through a supramolecular liposome infiltration promotion technology, is resistant to protease degradation and takes effect for a long time. According to the cosmetic application of the annular polypeptide and the supramolecular liposome product of the annular polypeptide, multiple key receptors can be targeted at the same time, sensitive circulation can be broken through, chromatosis can be controlled, meanwhile, the anti-allergic and whitening effects are achieved, and the multiple skin problems faced by people with sensitive skin can be solved in cooperation with an efficient delivery system.

The present invention relates to a method for producing cannabigerol and purifying it from a reaction mixture. The present invention also relates to the cosmetic use of cannabigerol for the inhibition of tyrosinase activity and / or the reduction of melanin production in the skin, in particular for reducing pigmentation of the skin, preferably for the improvement of the appearance of the skin in case of hyperpigmentation, lentigo or vitiligo. Furthermore, the present invention relates to cannabigerol for use in a therapeutic method for the inhibition of tyrosinase activity and / or the reduction of melanin production in the skin, preferably for use in a therapeutic method for the treatment and / or prevention of malign skin disorders, in particular skin cancer.

The present application relates to a whitening composition comprising a Nicotiana debneyi extract, and use thereof. The composition according to one embodiment regulates a melanin production pathway by reducing tyrosinase protein expression, and thus exhibits intracellular and extracellular melanin production inhibitory activity. Therefore, the present application provides a cosmetic composition for skin whitening, a health functional food composition for skin whitening, and a pharmaceutical composition for preventing or treating melanin hyperpigmentation diseases, all of which comprise the Nicotiana debneyi extract as an active ingredient.

The application discloses a kind of compositions to resist skin inflammation post pigmentation, the preparation raw material of the composition includes white atractylodes and lophatherum gracile, and the mass ratio of the white atractylodes and lophatherum gracile is (1-50):(6-15).The present application can regulate micro ribonucleic acid miR-146a expression, control skin inflammation from source, reduce inflammatory factor release, regulate the content of melanin, maintain the healthy homeostasis of epidermis, achieve the effect of whitening and brightening skin color, fading color spots, and restoring the healthy state of skin.And resist the negative effect of inflammation on skin color, by adjusting the expression of key inflammatory factors PGE2 affecting skin pigmentation in inflammation and melanin formation, so as to resist inflammatory pigmentation.

The present application provides a class of resorcinol derivative compounds shown in formula A, which can be used for preparing drugs for inhibiting hyperpigmentation, and cosmetic, non-therapeutic uses for treating hyperpigmentation. The compounds of the present application have significant effects on inhibiting pigment deposition caused by ultraviolet and / or visible light radiation, skin anti-aging, etc. Wherein W is T is H, or R 1 to R 8 The definitions are as defined in the specification.

The present disclosure relates to polymer adhesive systems, articles, compositions or patches comprising a water-insoluble polymer matrix that contains a compound, whereupon application of an occluded patch to the mammalian skin, results in the release of the compound on to the skin and an into the skin. In one aspect, the rate of release of the compound can be fully or partially solubilized by water miscible and immiscible excipients, liposomes and lipid nanoparticles, and where the released compound is available in the treatment of immune related diseases such as atopic dermatitis, psoriasis, alopecia areata, acne and hyperpigmentation.

The present invention relates to a cosmetic composition for skin whitening and, specifically, to: a cosmetic composition for skin whitening, comprising, as an active ingredient, at least one compound selected from the group consisting of chemical formulas 1 to 12 according to the present invention or a salt thereof; a pharmaceutical composition for preventing or treating pigmentation or hyperpigmentation; and a health functional food for skin whitening or alleviating hyperpigmentation diseases. The compound according to the present invention can effectively inhibit the activity of tyrosinase, and at the same time, has the activity of inhibiting melanin production and melanin secretion, and thus can be used not only in the manufacture of functional cosmetics and health functional foods for skin whitening, but also as a therapeutic agent for diseases caused by melanin hyperpigmentation.

This disclosure provides personal care compounds that reduce dark spots, even skin tone, brighten skin, and prevent hyperpigmentation. This disclosure also provides methods of preventing hyperpigmentation in a subject using the personal care compositions described herein.

Described herein are compositions and formulations for the treatment of acne, hyperpigmentation, wrinkles, and combinations thereof. The compositions comprise active agents in amounts of from about 0.1-20% based on the total weight of the composition, and an active agent comprising at least one hyperpigmentation agent in an amount of 15 weight % or less. In some embodiments, the composition comprises acetyl zingerone, azelaic acid, bakuchiol, and licorice extract.

Disclosed herein are cosmetic compositions. More particularly, disclosed herein are cosmetic compositions comprising at least one compound of General Formula (1), including but not limited to N,N,N',N'-tetrakis(2-hydroxyethyl)ethylenediamine (THEED), tetrahydroxypropyl ethylenediamine (THPE), and N,N,N',N'-tetrakis(2-hydroxypentyl)ethylenediamine, and at least one skin care benefit agent for combating the harmful effects of atmospheric pollution relating to hyperpigmentation in human skin.