The present disclosure relates to novel uses, compounds and topical compsitions of a compound of formula (I) comprising a 3,4-saturated 2H-
pyran moiety,, for covalently binding to a substrate comprising amino groups, and in particular to
skin and / or to hair; wherein the compound of formula (I) covalently binds to the substrate by the reaction of its 3,4-saturated 2H-
pyran moiety with the amino groups comprised by the substrate; wherein the compound of formula (I), after having covalently bound to the substrate, is providing color to the substrate, and / or binds one or more active ingredients to the substrate; wherein, if
active ingredient(s) is(are) present, the one or more active ingredients are, in particular and independently from each other, selected from a
moisturizer, a
pesticide, a fragrance, a pharmaceutical, a
skin whitening agent, UVA- and / or UVB-absorbing
moiety, a color-imparting moiety, a cosmetic hair
coating agent, and a primer for attaching dyes to hair; wherein the compound of formula (I) comprises the one or more active ingredients, if present, independently from each other: a) as the
active ingredient, or b) as a precursor of the
active ingredient, wherein the compound of formula (I) is cleavable to release the active ingredient from the precursor after the application of the compound of formula (I) to the substrate (in the following: "the corresponding precursor thereof"); and c) wherein one of A1 and A2 represents said active ingredient or the corresponding precursor thereof; wherein L1 and L2 represent, independently from each other, a
linker group or are absent; wherein each of A1 and A2 not representing one of the one or more active ingredients and precursors represents
hydrogen, a C1-C30 moiety, hydroxyl, amino, or a
halogen; wherein R1 represents
hydrogen or a protective group hydrolysable after application of the compound of formula (I) to the substrate; wherein R2 and R3 independently from each other represent H or a C1-C30 moiety; and wherein the compound is not
oleuropein aglycone, elenolic acid, or a
tautomer and / or a pharmaceutically acceptable salt thereof.