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77 results about "Malassezia" patented technology

Malassezia (formerly known as Pityrosporum) is a genus of fungi. Malassezia is naturally found on the skin surfaces of many animals, including humans. In occasional opportunistic infections, some species can cause hypopigmentation or hyperpigmentation on the trunk and other locations in humans. Allergy tests for this fungus are available.

Use of usnic acid and derivatives of usnic acid for preparation of medicaments for treating skin diseases caused by malassezia

The invention belongs to the field of pharmaceuticals, and relates to the new use of an usnic acid and derivatives of the usnic acid, specifically to the use of the usnic acid and the derivatives of the usnic acid for the preparation of medicaments for treating skin diseases caused by malassezia, in particular to the use of the usnic acid and the derivatives of the usnic acid for the preparation of medicaments for treating overmuch scurf, seborrheic dermatitis, atopic dermatitis and psoriasis caused by the malassezia. Inhibition test results show that an average diameter value of an inhibition zone is 20mm and the usnic acid can remarkably inhibit the growth of the malassezia; and a measurement result of a minimal inhibitory concentration (MIC) value of a sodium usnic acid for the inhibition of the malassezia shows that the growth of the malassezia is inhibited along with the rise of a medicinal concentration gradient of the usnic acid and the derivatives of the usnic acid. The usnic acid and the derivatives of the usnic acid disclosed by the invention can be used for preparing the medicaments for treating the skin diseases caused by the malassezia, and can also be used for preparing household chemicals and external preparations for preventing and treating the skin diseases.
Owner:晟薇药业(上海)有限公司

Traditional Chinese medicine extracting solution capable of resisting bacteria, removing acnes and treating blebs as well as application thereof and skin-care lotion prepared from traditional Chinese medicine extracting solution

The invention relates to a traditional Chinese medicine extracting solution capable of resisting bacteria, removing acnes and treating blebs as well as application thereof and skin-care lotion prepared from the traditional Chinese medicine extracting solution and belongs to the technical field of cosmetics. The traditional Chinese medicine extracting solution is prepared from the following components: mulberry twig / or mulberry root extract, dandelion extract and chamomile extract; the extracting solution contains a plurality of types of active and effective components, can be used for effectively inhibiting or killing coryneform bacteria on surfaces of the acnes, and acne propionibacterium, staphylococcus epidermidis and malassezia fufur of pathogenic bacteria in the acnes, and has the effect of removing the acnes on faces and backs, thus treating both symptoms and root causes; meanwhile, bleb viruses are inhibited or killed, so that the skin-care lotion prepared from the traditional Chinese medicine extracting solution can be used for resisting the bacteria, removing the acnes and effectively inhibiting the bleb viruses; and the skin-care lotion has a good curative effect and a lasting effect, does not bounce and the like and has no skin irritation effect and other side effects.
Owner:SOUTHWEST UNIV

Amino acid shampoo having functions of restraining bacteria, relieving itching, protecting hair and repairing damaged hair

The invention discloses amino acid shampoo having functions of restraining bacteria, relieving itching, protecting hair and repairing damaged hair. The amino acid shampoo comprises the following components in percentage by mass of 0.1-5% of a scarlet kadsura root extract, 3-8% of an amino acid surfactant, 3-8% of glycerine, 2-6% of sorbitol, 0.1-0.5% of ethylenediaminetetraacetic acid disodium, 1-3% of oat kernel oil, 2-6% of an olive leaf extract, 0.1-0.5% of citric acid, 0.1-0.5% of PEG-120 methyl glucose dioleate, 1-5% of polyquaternary ammonium salt-7 and 0.3-0.9% of phenoxyethanol. According to the amino acid shampoo disclosed by the invention, the effects of the scarlet kadsura root extract for resisting oxidation, restraining inflammation and restraining bacteria are utilized, and the scarlet kadsura root extract, the oat kernel oil and the olive leaf extract are compounded in a specific proportion, so that the amino acid shampoo can restrain the production of dandruff caused byexcessive proliferation of scalp cells caused by propagation of malassezia, restrain itching caused by seborrheic dermatitis, restrain the production of the dandruff caused by oxidization stress of the scalp cells, besides, nourish the scalp and promote scalp health.
Owner:肇庆市凯捷科技有限公司

Application of fungal microbiome as marker in preparation, treatment, screening and lung cancer diagnosis

The invention provides application of a fungal microbiome as a marker in preparation, treatment, screening and lung cancer diagnosis. By constructing a fungal microbiome DNA enrichment and extractionmethod, fungal microbiome DNA is extracted from tissues, feces and alveolar lavage fluid, and ITS sequencing and metagenome sequencing are applied to fungal microbiome and gene function analysis, wherein aspergillus polyangius is enriched in tumor tissues, candida albicans is enriched in tumor tissues and para-carcinoma tissues, and malassezia is enriched in alveolar lavage fluid; by detecting these target strains or molecular markers, lung cancer can be found and intervened as early as possible, and the target strains or molecular markers are expected to be used as important indicators for lung cancer screening; and in addition, the characteristics of the type and quantity of fungi are obtained through DNA sequencing results of fungal florae in feces, tissues and alveolar lavage fluid samples of different parts of lung adenocarcinoma patients, and the lung cancer is more accurately screened and diagnosed in an assisted mode based on the quantity and ratio characteristics of the fungispecifically enriched in the lung cancer.
Owner:SHANGHAI JIAOTONG UNIV SCHOOL OF MEDICINE

Primer group and kit for simultaneously detecting multiple pathogenic fungi

ActiveCN112522434AStrong species specificityImprove detection efficiencyMicrobiological testing/measurementDNA/RNA fragmentationFonsecaea pedrosoiMultiplex
The invention discloses a primer group and kit for simultaneously detecting various pathogenic fungi. The primer group comprises 14 pairs of primers, and the primers can perform specific multiplex amplification on DNA sequences of 14 target fungi, wherein the target fungi comprise candida albicans, candida tropicalis, candida glabrata, candida parapsilosis, candida krusei, aspergillus fumigatus, aspergillus terreus, trichophyton mentagrophytes, trichophyton rubrum, epidermophytom floccosum, sporothrix schenckii, microsporum caninum, fonsecaea pedrosoi and malassezia fufur. The kit adopts a multiple fluorescence labeling PCR amplification technology for multiplex amplification, multiple common pathogenic fungi can be identified at the same time through a one-time reaction, the detection efficiency is high, the speed is high, and the cost is low; in addition, interspecific and intraspecific comparison can be performed on sequences in a fungus ITS or beta-tubulin database, an intraspecific conserved region is selected to design an amplification primer, and very strong species specificity is achieved. The whole detection process can be completed within 2-3 hours, the detection speed ishigh, and the requirement for rapid detection of clinical samples can be met.
Owner:THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIV +1

Plant anti-dandruff and itching-relieving composition, plant anti-dandruff and itching-relieving shampoo and preparation method thereof

The invention relates to the field of skin care products, and particularly discloses a plant anti-dandruff and itching-relieving composition, a plant anti-dandruff and itching-relieving shampoo and a preparation method of the plant anti-dandruff and itching-relieving shampoo. The plant anti-dandruff and itching-relieving composition is prepared from the following components in percentage by mass: 40.0-60.0% of a bamboo hat leaf extract and 40.0-60.0% of an oat kernel extract. The plant anti-dandruff and itching-relieving composition is obtained by reasonably matching the bamboo hat leaf extract and the oat kernel extract according to a specific proportion, and is applied to hair care products. The bamboo hat-shaped bamboo hat leaf extract can effectively inhibit the growth of malassezia, maintain the healthy environment of scalp and reduce scurf. The oat kernel extract can inhibit the activation of an important transcriptional regulatory factor NF-kB expressed by proinflammatory protein, and efficiently diminish inflammation and relieve itching. The oat kernel extract can effectively relieve irritation of the environment to the scalp, and the anti-dandruff effect of the bamboo hat leaf extract is enhanced.
Owner:河南董欣生物科技有限公司
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