621 results about "Paeonol" patented technology

The present invention discloses an eugenol nano emulsion compound, characterized in that the granule diameter of the nano emulsion compound is within 1 to 100nm; the raw materials with weight percentage includes 1.0 to 10.0 percent of eugenol, 0.5 to 8.0 percent of eucalyptus oil, 0.1 to 6.0 percent of pennyroyal, 0.1 to 3.0 percent of paeonol, 0.05 to 5.0 percent of citionella oil, 0.05 to 3.0 percent of camphor, 7.5 to 35.3 percent of emulsifying agent, 0.2 to 3.8 percent of co-emulsifier and the rest of water; the total weight percentage of the raw materials is 100 percent. The eugenol nano emulsion compound has the functions of dispelling mosquitoes, relieving itching, killing pain, reducing inflammation and resisting bacteria. The present invention is used to dispel mosquitoes and rapidly relieve itching and red swelling on the skin after bitten by mosquitoes. The present invention has the advantages of strong permeability, good stability, good invasive, long acting time, significant effect, simple preparation method and easy promotion and application.

The invention mainly relates to a skin moisturizer containing peony essential oil. The skin moisturizer is prepared from the following raw materials in parts by weight: 2-4 parts of the peony essential oil, 1-3 parts of peony seed essential oil, 0.5-1 part of paeonol, 10-30 parts of aloe juice, 0.5-1.5 parts of banana quereetin, 0.2-0.6 parts of vitamin E, 0.2-0.8 parts of polyethylene glycol, 3-7 parts of glycerinum, 0.5-1.5 parts of citric acid, 0.2-0.8 parts of triethanolamine, 0.1 parts of lauryl sodium sulfate and 50-70 parts of water. The skin moisturizer integrates multiple functions of resisting oxidization and irritability, shrinking pores, realizing antibiosis, diminishing inflammation, removing acne, relieving itching, suppressing stains, removing grease, retaining moisture, moistening the skin, enhancing smoothness and elasticity, preventing and restoring wrinkles and microgrooves, clearing away free radicals, delaying aging and the like, takes natural plant extracts as the raw materials, does not have side effects and has an obvious treating effect after being used for a long time.

The invention pertains to the field of cosmetics, and discloses a paeonol-bletilla striata polysaccharide inclusion compound, a preparation process and the application thereof. Two components of the inclusion compound have the weight percentage as follows: 70%-95% of the bletilla striata polysaccharide and 5%-30% of the paeonol. The inclusion compound can be taken as a cosmetic additive, and has obvious effects of removing spot and whitening skin, delaying skin senility, moistening skin, resisting bacteria and relieving inflammation, and the like, after being added to relevant cosmetic products.

The invention discloses a washing and disinfecting solution for household tableware, belonging to the field of commodity chemicals. The washing and disinfecting solution comprises, by weight, 2% to 5% of trisodium phosphate, 1% to 5% of sodium carbonate, 0.1% to 1% essence, 0.1% to 1% of an antiseptic, 0.5% to 1% of a handguard factor and 10% to 5% of AES; the washing and disinfecting solution further comprises Chinese herbal extractants, i.e., paeonol and baicalin. The washing and disinfecting solution provided by the invention has both functions of washing and disinfecting, enables washing and disinfection to be completed at the same time and has the advantages of conservation of water, easy utilization and no harmful ingredients to a human body.

The invention relates to the medical technical field, in particular to a paeonol micro-emulsion preparation and a preparation method thereof. The paeonol micro-emulsion preparation consists of components with the weight percentage as follows: 0.1 percent to 2 percent of paeonol, 10 percent to 25 percent of surfactant, 5 percent to 30 percent of cosurfactant, 5 percent to 15 percent of oil phase and 40 percent to 70 percent of deionized water. The mouse percutaneous experiment in vitro shows that the paeonol micro-emulsion prepared by the invention has obviously higher capacity of penetrating through the horny layer than the saturated aqueous solution of paeonol (p is less than 0.05), and the paeonol micro-emulsion can penetrate into the skin deeply to take curative effect within a short time and also has certain sustained and controlled release function. At the same time, the paeonol micro-emulsion improves the solubility of the paeonol obviously, increases the drug loading quantity of the preparation and reduces the drug administration times and the dosage. The paeonol micro-emulsion preparation has simple preparation method and uniform grain diameter of the preparation, has the advantages of being safe, stable and efficient and, can be used for preparing dermal medication preparation or cosmetic.

The invention discloses a method for extracting paeonol by use of the CO2 supercritical extraction technology. The method comprises the following steps: washing cortex moutan, drying, grinding, seiving and performing ultrasonic treatment; adding an appropriate amount of beta-cyclodextrin, granulating and drying; uniformly mixing emu oil serving as an entrainer with the raw material powder; feeding the granulated particles into a supercritical extraction kettle for CO2 supercritical extraction; refrigerating the paeonol extract liquid in the supercritical extraction kettle and taking out to obtain an automatic-layering extract, wherein the upper layer is light yellow liquid, and the lower layer is light red brown solid; and separating the liquid to obtain high-purity active monomer paeonol. The method disclosed by the invention has the advantages of simple extraction process, high extraction rate, low extraction temperature, short extraction time and the like; the yield of paeonol can exceed 1.4%; and moreover, CO2 is non-toxic and residue-free, the energy consumption is reduced, cyclic use can be realized, the shortcomings of the traditional extraction method that the paeonol is easily volatilized and the yield is low are overcome, and the application prospect is broad.

The invention relates to a health-care product, in particular relating to a health-care food component taking peony extract as a base material and an application thereof. The peony extract is peony juice, paeonol or peony oil; and accessory ingredients are divided into three types, namely an oral liquid prepared from peony juice, collagen peptide, natural juice, Vc (vitamin C), Isomalt, protein candy and purified water, an oral liquid prepared by taking the paeonol as a base material, and a soft capsule prepared by taking the peony oil as a base material. In the health-care food component, the application of the beneficial components of the base material of the peony is achieved, so that the waste of the root, stem or flower of the peony is effectively overcome; and as the health-care food component is of an oral liquid or capsule form, the technical difficulties that in production of the peony, the raw material is strong in seasonality, needs concentrated supply, can not be stored and also can not be supplied throughout the year are effectively solved, and the recycling utilization of the peony and further expansion of the health-care function are achieved.

The invention relates to a Chinese herbal medicinal wet wipe for cleaning and disinfection of the skin, which relates to the technical field of daily necessities. The wet wipe comprises a wet wipe solution and a carrier for the wet wipe solution. The invention is characterized in that raw materials for preparation of the wet wipe solution comprise, by weight, 0.5 to 1% of lavender essential oil, 0.4 to 0.8% of cassia twig essential oil, 0.3 to 1% of cablin patchouli herb essential oil, 0.01 to 0.1% of menthol, 0.01 to 0.2% of paeonol, 0.3 to 1% of a coptis extract, 0.2 to 1% of a witch hazel extract, 0.5 to 2% of hydrogenated castor oil and 5 to 10 % of ethanol, with the balance being water. According to the invention, a non-woven fabric is used as the carrier; the wet wipe is convenient to use and can kill common pathogenic bacteria like escherichia coli, staphylococcus aureus, bacillus subtilis, aspergillus flavus, Gram-positive cocci, shigella dysenteriae, helicobacter pylori and Candida albicans; the wet wipe is mild-natured, natural and safe because of utilization of a Chinese herbal medicine formula and can overcome the problems of irritation and corrosivity of currently-used chemical disinfection products.

Liuwei Dihuang Decoction extract, comprising 11.4-17% by weight of polysaccharides, and/or 1.85-2.27% by weight of total glycosides (morroniside, loganin, paeoniflorin) and /or 23.5-35.5% by weight of mannotriose, wherein Liuwei Dihuang Decoction is composed of six traditional Chinese medicines of Rehmannia glutinosa, Cornus officinalis, Chinese yam, Alisma, Paeonol and Poria cocos in a weight ratio of 8:4:4:3:3:3.

The invention provides a new preparation method and a quality control method of a pill containing cassia twig and tuckahoe, The preparation method have the advantages of few production steps, short production cycle, high production mechanization, stable preparation quality, high content of effective ingredients, fast disintegration, high bioavailability, small dose, convenient administration and the like. The invention also provides the quality control method of cinnamyl aldehyde, cinnamic acid, paeonol, peoniflorin and amygdalin in the pill containing cassia twig and tuckahoe.

The invention discloses an analysis method for the content of paeonol based on chromatograph-spectrograph combination and sub-space included angle criteria. The analysis method is specifically carried out according to the following steps: establishing a paeonol standard spectrum base; preparing a sample to be detected and acquiring an ultraviolet spectrum; establishing a modeling background database; and determining the content of paeonol in the sample to be detected. According to the invention, the rapid analysis method for the content of paeonol is established by the liquid phase-ultraviolet visible spectrograph combination and the application of the sub-space included angle criteria. With regard to the determination of similar products, samples can be detected in a large batch by one modeling. Compared with a high performance liquid chromatography, the established method is stable and reliable and is simple and convenient to operate; the samples do not need to be subjected to complicated pre-treatment; and a relatively practical quantitative analysis technology is provided for rapidly determining the content of paeonol and can be popularized and applied to other paeonol product detection fields.

The invention relates to a preparation and applications of a paeonol controlled-release preparation in the technical field of the medicine. The paeonol controlled-release preparation refers to a group of controlled-release and long-time effective preparations which contain the microspheres and gel matrix tablets used for preparing tablets or capsules, and thermosensitive in situ gel for external use, wherein the specifications of the prepared paeonol controlled-release preparation are 60mg and 120mg; under special conditions, the accumulative release rate at 2h is less than 20% of the labeled amount, the accumulative release rate at 6h is 40-60% of the labeled amount and the accumulative release rate at 12h is more than 80% of the labeled amount respectively; and the paeonol controlled-release preparation can be used to cure rheumatoid arthritis. By using the thermosensitive in situ gel for external use, the preparation residence time of the affected part can be significantly prolonged.

Disclosed is the use of paeonol in preparing medicament for the prevention or treatment of fatty liver, and also the use of medicinal combination preparation of paeonol with medicinal carrying agent in preparing medicaments for the prevention and treatment of fatty liver disease, the dose forms of the medicament include soft capsules, drop pills, pills, powders, tablets, capsules, granules, injections, fluid infusions, freeze-dried powders for injection, suppositories, film agents, tiny capsules, tincture, syrup, oral liquids and other pharmaceutically acceptable dose forms.

The invention provides a preparation process and a quality control method of a cassia twig poria cocos preparation. The preparation method has the advantages of less production steps, short production period, high production mechanical degree, stable quality of the preparation, high content of effective components, rapid disintegration, high bioavailability, small dose oral administration, convenience in oral administration and the like. The invention also provides a quality control method of cinnamaldehyde, cinnamic acid, paeonol, paeoniflorin and amygdalin in a cassia twig poria cocos pill.

The invention belongs to the field of toothpaste, and in particular relates to radix ginseng toothpaste. The radix ginseng toothpaste is prepared from the following components: 60-70% of sorbitol, 15-20% of hydrated silica, 1.0-10% of glycerin, 1.0-5% of polyethylene glycol-8, 2.0-2.5% of sodium lauryl sulfate, 1.0-1.5% of edible essence, 0.5-1.0% of carrageenan, 0.5-1.0% of cellulose gum, 0.2-0.25% of sodium saccharin, 0.2-0.5% of paeonol, 0.1-0.5% of tranexamic acid, 0.1-0.2% of tetrasodium pyrophosphate, 0.1-0.3% of sodium benzoate, 0.08% of a radix ginseng extract and the balance of water, wherein the sum of percents of the components is 100%. The radix ginseng toothpaste has the beneficial effects of having the functions of killing bacteria, maintaining the oral cavity to be fresh and preventing gingival bleeding.

The invention relates to a synthetic method for silane coupling agent modified acrylic resin with side-chain suspended paeonol structure, which comprises following steps: adding paeonol, N-methylol acrylamide and anhydrous alcohol in a conical flask in sequence; adding anhydrous aluminum chloride after the N-methylol acrylamide is completely dissolved; stirring in water bath for reaction; removing part of alcohol through rotary evaporation after reaction; pouring concentrated solution in solution of dilute sulfuric acid and aluminum chloride, and stirring for removing catalyst aluminum chloride, then light red crude product is obtained through pumping filtration and drying; dissolving light red crude product using mixed solution with ethyl acetate and ethanol in volume ratio of 3 to 2, then white solid substance is obtained through recrystallization after the insoluble matters is filtered out. The synthetic method for silane coupling agent modified acrylic resin with side-chain suspended paeonol structure has the advantages of controllable reaction process, short reaction time, high applicability to organotin-free self-polishing antifouling coating, high antifouling activity and fungicidal activity, and ability to prevent the adherence of marine organism on the facilities.

The invention relates to a clathrate of paeonol and the preparation method and the quality detection method thereof. The preparation method of the clathrate of paeonol comprises the following steps: adding beta-cyclodextrin into water, stirring, and heating; adding paeonol into ethanol, heating to dissolve, pouring into the beta-cyclodextrin solution, milling with a colloidal mill, discharging, standing at room temperature, performing suction filtering, and drying.

The invention discloses a quality detection method of a ginseng basis-consolidating oral solution with the functions of nourishing yin and qi and consolidating basis. According to the quality detection method, the preparations of ginseng, dogwood, cortex moutan and rhizoma alismatis are distinguished with thin layer chromatography, and meanwhile the contents of ginsenosides Rg1 and Re of the ginseng, the content of paeonol of the cortex moutan, the contents of morroniside and loganin of the dogwood in the preparations are measured by adopting HPLC (high performance liquid chromatography). The quality detection method disclosed by the invention is stable, reliable, high in specificity and good in repeatability; content determination is carried out by selecting monarch drugs such as ginseng and cortex moutan containing volatile constituents in the prescription, so that the quality of the ginseng basis-consolidating oral solution can be comprehensively and effectively controlled, the stabilization for product quality is facilitated, the safety and effectiveness of clinical medication are guaranteed, and requirements of medical treatment and market are preferably met.

The invention belongs to the technical field of plant biology and in particular relates to a method for extracting paeonol from paeonia suffruticosa roots. The method comprises the steps of picking, complex enzyme liquid preparation, ultrasonic treatment, centrifugal treatment and reduced pressure distillation. The method has the beneficial effects that enzyme treatment is firstly carried out on paeonia suffruticosa roots and barks at 30 DEG C for 20 minutes, so that the cell walls of the paeonia suffruticosa roots and barks and the interstitial structures of the cell walls can suffer from changes such as local loosening, swelling, collapse and the like; short-time ultrasonic treatment is then carried out on the paeonia suffruticosa roots and barks, ultrasonic waves generate strong impact waves and microjet inside the liquid, and the powerful impact flow can effectively reduce and eliminate the blocking layer between a solvent and an aqueous phase, thus increasing the mass transfer rate; besides, the impact flow generates a physical shear force towards cell tissues, so that the cell tissues deform, fracture and release inclusions, the cell walls and the interstitial structures of the cell walls suffer from local loosening and swelling, the extraction process of paeonol in the cells is accelerated, and the effect of getting twofold results with half the effort is achieved.