94 results about "Gallic acid ester" patented technology

This invention relates to the field of textile materials technology, and proposes a fiber for headscarves and its preparation method. The fiber for headscarves comprises the following components by weight: 100 parts PET resin, 2-4 parts modified graphene oxide, 8-10 parts toughening agent, and 0.5-1 parts antioxidant; the modified graphene oxide comprises the following raw materials by weight: 2-5 parts gallic acid fatty ester and 1 part graphene oxide. This technical solution solves the problem of low strength in existing PET fibers for headscarves.

The present application relates to a kind of self-setting composite bone implants based on gallic acid complex salt and preparation method thereof, belong to bone repair material field.The present application is specifically related to a kind of self-setting composite bone implants, it is characterized in that, component A, component B and component C, the component A is gallic acid and the complex salt of at least two metal elements, wherein the at least two metal elements are the metal element of promoting bone tissue regeneration or the trace metal element required by human body, and the at least two metal elements include calcium, the component B is the complex of calcium / strontium chondroitin sulfate and calcium sulfate, and the component C is magnesium calcium hydrogen phosphate complex.The self-setting composite bone implant of the present application has the characteristics of antibacterial, anti-inflammatory, promoting osteogenesis, instant shaping and all degradation, can meet the clinical needs of bone tumor, bone injury and the like, has wide application prospect in various bone repair, reconstruction and replacement.

The application belongs to the technical field of pharmaceutical chemistry, and particularly relates to clofazimine-organic acid co-crystals, a preparation method and application thereof. The clofazimine-organic acid co-crystal is one of clofazimine-ferulic acid monohydrate co-crystal, clofazimine-ferulic acid co-crystal, clofazimine-glutaric acid co-crystal, clofazimine-glycolic acid co-crystal (CFZ-GA 1:1), clofazimine-glycolic acid co-crystal (CFZ-GA 1:1.5), clofazimine-salicylic acid co-crystal, clofazimine-L-aspartic acid co-crystal, clofazimine-L-pyroglutamic acid co-crystal, clofazimine-gallic acid co-crystal, clofazimine-succinic acid co-crystal, clofazimine-tartaric acid co-crystal and clofazimine-DL-mandelic acid co-crystal. The clofazimine-organic acid co-crystal provided by the application significantly improves the solubility and fluidity of clofazimine, thereby improving the bioavailability of clofazimine, and has a broad medicinal prospect.

This invention provides a plant growth regulatory activity of a new biologically active synthetic molecule methanone-(3′,4′,5′-trimethoxy) phenyl, 1-naphthyl, 2-O-4″-ethyl but-2″-enoate. More particularly, the invention relates to the potent plant growth promoting activity of a gallic acid derivative having a structure represented by Formula 1 and a molecular formulae C26H26O7. This invention also provides a novel process for preparation of said molecule from a naturally occurring compound and testing it for growth regulating activity using Bacopa test system developed at CIMAP (Khanuja et al., 2001).

This invention relates to the field of bioimmobilization technology, and discloses a metal-organic framework composite material, its preparation method and application, a method for immobilizing biomolecules, and the immobilization of biomolecules. The metal-organic framework composite material comprises a metal-organic framework material and natural polyphenols modified on the surface of the metal-organic framework material; wherein the metal-organic framework material is UIO-66-NH2, and the natural polyphenols are selected from at least one of tannic acid, gallic acid, and dopamine. This metal-organic framework composite material can achieve efficient, mild, and stable immobilization of biomolecules, significantly improving the versatility, catalytic activity, and stability of immobilized biomolecules.

This invention discloses a compound preparation for treating vascular dementia and its preparation method. The active pharmaceutical ingredient consists of protopanaxadiol and gallic acid in a 1:1 mass ratio, and the dosage form is liposomes. The preparation method includes extraction, mixing, liposome preparation, and optional freeze-drying steps: protopanaxadiol and gallic acid are extracted and purified from ginseng rhizome and Terminalia chebula fruit, respectively. After mixing, they are combined with phospholipids and cholesterol to prepare a lipid membrane. The membrane is then homogenized by hydration, low-temperature ultrasound, and high-pressure microfluidic jet to obtain a homogeneous liposome suspension, which can be further freeze-dried into a freeze-dried powder. The 1:1 composition of protopanaxadiol and gallic acid targets multiple points on the pathological mechanism of vascular dementia, showing significant therapeutic effects and broad application prospects. This preparation uses a liposome dosage form to improve the bioavailability of the active ingredient, the preparation process parameters are controllable, the active ingredient has high purity, the liposomes have uniform particle size, high encapsulation efficiency, and good stability.

The present invention relates to cocrystalline forms of 4-[4-[3- chloro-4-[l-(5-fluoro-2-pyridyl)-2-hydroxy-ethoxy]pyrazolo[l,5- a]pyridin-6-yl]-5-methyl-triazol-l-yl]piperidine-l-carbonitrile, R- enantiomer ("Isomer 2"), with gallic acid (I), and to cocrystalline forms of 4-[4-[3-chloro-4-[l-(2-pyridyl)-2- hydroxy-ethoxy]pyrazolo[l,5-a]pyridin-6-yl]-5-methyl-triazol-l- yl]piperidine-l-carbonitrile, R-enantiomer ("Isomer A"), with gallic acid or nicotine amide (II) The compounds are fibroblast growth factor receptor 3 (FGFR3) inhibitors for use in methods of treatment of e.g. cancer. Provided herein are also methods for the preparation of said cocrystalline forms.

The present application relates to the technical field of modified polyamide, and particularly relates to a graphene-reinforced polyamide antibacterial composite fiber and a preparation method and application thereof.The present application comprises the following steps: S1, preparing edge carboxylated graphene; S2, preparing PEG grafted graphene; S3, preparing a gallic acid-dopamine amide compound; S4, preparing a GA-PEG-dopamine-G composite material; S5, preparing a master batch by mixing the GA-PEG-dopamine-G composite material with polyamide 6 granules; and performing melt spinning on the master batch to obtain the graphene-reinforced polyamide antibacterial composite fiber.The composite fiber has excellent mechanical properties, particularly elongation at break and tensile strength, and also has excellent antibacterial properties.

This invention discloses a method for determining the content of gallic acid and (+)-catechin in *Hedysarum heterotropoides* medicinal materials. After reflux treatment with 60% methanol solution in a water bath, the *Hedysarum heterotropoides* medicinal materials are subjected to high-performance liquid chromatography (HPLC) with octadecyl-bonded silica gel as the stationary phase and acetonitrile (A)-0.1% phosphoric acid aqueous solution (B) as the mobile phase. The peak area values ​​of gallic acid and (+)-catechin showed good linearity in the injection amounts of 10.00–100.0 μg and 200.0–2000 μg, respectively, with average recoveries of 98.31% and 97.68%, and RSD values ​​of 1.2% and 1.2%, respectively. The method is simple and accurate, and can be used for the determination of gallic acid and (+)-catechin content, providing a theoretical basis for the quality control of *Hedysarum heterotropoides* medicinal materials.

The application provides a kind of injectable responsive hydrogel loaded with chitosan oligosaccharide-gallic acid octyl ester and its preparation method and application, and the preparation method comprises: chitosan oligosaccharide-gallic acid octyl ester conjugate is added into carboxymethyl chitosan solution to obtain a mixed solution;The mixed solution and the oxidized tannic acid solution are mixed to form an injectable responsive hydrogel.The three-dimensional hydrogel network formed by carboxymethyl chitosan and oxidized tannic acid is constructed, chitosan oligosaccharide-gallic acid octyl ester is stably loaded in the gel system, can form a physical barrier in the local wound and provide sustained support, thereby significantly improving the retention capacity of antibacterial components in the wound site, prolonging its effective action time, reducing the need for repeated administration.Effectively solve the problem that antibacterial functional materials are difficult to stay in humid infected wounds for a long time and are easy to lose with exudate, can be applied and prepared into antibacterial drugs.

This invention belongs to the field of microbial fermentation technology, and provides a method for increasing the polyphenol content of mulberry leaves through compound fermentation with lactic acid bacteria, as well as the fermentation product and its uses. Mulberry leaves are dried, pulverized, and sieved to obtain mulberry leaf powder; *Lactobacillus plantarum* ATCC8014, *Lactobacillus casei* ATCC334, and *Lactobacillus acidophilus* ATCC4356 are activated and mixed in a 1:1:1 ratio to obtain a compound bacterial solution; a fermentation substrate is prepared at a material-to-liquid ratio of 1:50 to 1:200 and sterilized, inoculated at 1% to 5%, and fermented at 33 to 41°C for 12 to 60 hours to obtain the fermented mulberry leaf product; the supernatant is separated from the solid-liquid mixture, filtered through a 0.22 μm filter, and freeze-dried to obtain the fermentation product. Under preferred conditions (1:100, 3.1%, 37.5°C, 49 hours), the total polyphenol content reaches 46.80 mg / g (gallic acid equivalent). The fermentation product can be used to prepare food or pharmaceutical compositions that improve indicators related to metabolic syndrome.

The application relates to the technical field of pressure-sensitive materials, and provides a self-repairing pressure-sensitive material based on solvent replacement and a preparation method and application thereof, the pressure-sensitive material comprising a hydrogel; the hydrogel comprises polyvinylpyrrolidone and gallic acid; a dynamic hydrogen bond network is formed between amide carbonyl in a molecular chain backbone of at least part of the polyvinylpyrrolidone and hydroxyl of at least part of the gallic acid; the dynamic hydrogen bond network changes a fluid structure of the hydrogel with strain change; and intermolecular pi-pi stacking structures are formed between at least part of the gallic acid molecules. The preparation method is a solvent replacement method for preparing the hydrogel, and the application has obvious advantages in aspects of preparation process simplicity, bacteriostatic safety, pressure-sensitive performance and durability, and can effectively solve problems of poor mechanical matching, unstable interface and easy damage of existing hydrogel pressure sensors, and has outstanding technical effects.

This invention discloses a high-strength carbon fiber modified plastic and its preparation method. By weight, it comprises the following raw materials: 90-100 parts polypropylene, 8-12 parts modified carbon fiber, 3-5 parts maleic anhydride-grafted polypropylene, 2-4 parts toughening agent, 0.7-1.1 parts antioxidant, and 0.5-0.8 parts lubricant. This high-strength carbon fiber modified plastic achieves its goal by subjecting the carbon fiber surface to specific multi-step modification, sequentially introducing an aminosilane coupling layer, a gallic acid amide bond linking layer, and an itaconic acid active double bond functional layer. This forms an inside-out covalently bonded interface system, transforming the simple physical contact between the carbon fiber and the polypropylene matrix into a chemical bond. Furthermore, by combining maleic anhydride-grafted polypropylene as an interface compatibilizer and ethylene-octene copolymer as a toughening agent, the formulation design ensures both high strength and material toughness, resulting in a high-strength carbon fiber modified polypropylene composite material with balanced mechanical properties.

Nanoparticle system comprising a metal, coated with polyethylene glycol (PEG), which is functionalized with a polyphenol-type organic acid, manufacturing procedure and use of said system. The present invention relates to a nanoparticle system comprising a metal selected from silver and gold, coated with polyethylene glycol (PEG), which is functionalized with a polyphenol-type organic acid selected from caffeic acid, gallic acid, and ferulic acid. The present invention also relates to a process for manufacturing said nanoparticle system and to the therapeutic and cosmetic use of said nanoparticle system.

The application belongs to the technical field of carbon dioxide hydrogenation, and particularly relates to a preparation method and application of an Ir monatomic catalyst for carbon dioxide hydrogenation to produce formic acid. A metal precursor, acetylacetone iridium Ir(acac)3, is in-situ coordinated and encapsulated in a complex cavity assembled with gallic acid coordination, and is carbonized at different temperatures (800 DEG C, 900 DEG C and 1000 DEG C) respectively, thereby successfully preparing monatomic catalysts with different coordination environments (Ir-N4, Ir-N3 and Ir-N2). The method is simple in operation, the obtained material structure is controllable, the carbon skeleton has good thermal stability and has a high specific surface area, the Ir is atomically dispersed and does not agglomerate, and in addition, the metal loading is low. The precise synthesis strategy of the catalyst is simple and feasible, easy to industrial production, can meet the needs of future carbon dioxide resource utilization and industrial production of bulk chemicals formic acid, and has good application prospect.

The application provides a kind of targeting drug-loaded liposome combined functional hydrogel and its preparation method and application, including active targeting liposome and functional gelatin hydrogel, make the active targeting liposome disperse in functional gelatin hydrogel, under the photo initiator, ultraviolet crosslinking solidification obtains the targeting drug-loaded liposome combined functional hydrogel;The functional gelatin hydrogel includes methacrylic anhydride grafting gelatin hydrogel and gallic acid grafting gelatin hydrogel, and the active targeting liposome is RGD peptide modified drug-loaded liposome.The application overcomes the defects of poor targeting, large systemic toxic side effects and insufficient regulation of joint immune microenvironment in the existing methotrexate single drug therapy for rheumatoid arthritis.

The invention relates to a method for preparing a polyester polymer material, which comprises preparing a reaction medium comprising a mixture of at least one monomer chosen from ω-hydroxylated fatty acids and ω-hydroxylated fatty acid esters of an alcohol comprising an aliphatic chain comprising from 1 to 18 carbon atoms, and at least one phenolic compound, the total content of phenolic compound(s) being within a range of values from 0.3 to 42 mg equivalent of gallic acid per gram of the mixture. The method then comprises heating this reaction medium in order to carry out the polymerisation of the monomer and the phenolic compound and the cross-linking of the polymer thus formed.

This invention discloses a polypropylene composition and its applications, belonging to the field of polymer composition technology. The invention provides a polypropylene composition comprising polypropylene, a hindered phenolic antioxidant, a phosphite antioxidant, guaiacol, gallic acid, a dispersant, a light stabilizer, and a metal ion passivator. By incorporating the above components, the polypropylene polymer provided by this invention can synergistically enhance the anti-phenolic yellowing effect of the hindered phenol-phosphite composite antioxidant, resulting in a polypropylene composition that possesses both good anti-phenolic yellowing effect and good dyeing adsorption rate.

The invention discloses a melogabalin besylate-containing pharmaceutical composition and a preparation method thereof, the preparation prescription adopts vitamin E polyethylene glycol succinate, gallic acid or tocopheryl succinate as antioxidants, and the specific antioxidants are screened out, so that the prepared melogabalin besylate pharmaceutical composition is better in stability and better in curative effect. Oxidative degradation impurities are effectively controlled, and the effectiveness and safety of melogabalin besylate are improved. In addition, the preparation method is stable, controllable and easy to amplify.

The present invention relates to a composition for dyeing hair. The composition for dyeing hair of the present invention can be used as a single formulation or applied as a two-formulation system comprising a dyeing part and a base part, and comprises tannic acid, gallic acid, and a ferrous salt in an optimal ratio, thereby realizing excellent dyeability compared to conventional chemical hair dyes. In addition, the particle size distribution of a mixture in the dyeing part of the composition for dyeing hair of the present invention enables uniform dispersion on the surface of hair and provides effective penetration into the hair in an aqueous environment, and the composition provides a stable dyeing effect under various conditions including high-temperature storage.

This invention belongs to the field of micro-electromechanical biosensing technology, specifically relating to a flexible sensor for real-time monitoring of gallic acid content in plants, its preparation method, and its application. The flexible sensor includes a flexible substrate and a working electrode, a reference electrode, and a counter electrode disposed on the substrate. The working electrode is a laser-induced graphene electrode (LIG) with its surface sequentially modified with black phosphorus nanosheets (BP), sheet-like titanium carbide (MXene), and manganese phosphorus sulfur (MnPS3). This flexible sensor can achieve online detection and analysis of gallic acid in plant tissues at different stages. Because it is a patch-type adaptive sensor for plant surfaces, it does not cause fundamental damage to the detected material, allowing the material to continue growing until maturity. Furthermore, the layer-by-layer assembly of the working electrode with black phosphorus nanosheets, MXene, and MnPS3 achieves highly sensitive detection of gallic acid, offering advantages such as lightweight portability, excellent electrical performance, and high integration.

The invention relates to the technical field of coreopsis tinctoria refined components and preparation and application, and provides a coreopsis tinctoria refined component and a preparation method and application thereof.The coreopsis tinctoria refined component comprises, by mass, 11 specific components of phenolic acids, flavonol, flavanol and flavonoid, and the 11 specific components comprise, by mass, 2 parts of gallic acid, 1 part of potassium sorbate, 1 part of potassium sorbate, 1 part of potassium sorbate and 1 part of potassium sorbate. The health-care food is prepared from the following raw materials in parts by weight: 3 parts of chlorogenic acid, 14 parts of quercetin, 18 parts of catechin, 5 parts of citric acid, 2-3 parts of procyanidine B, 3 parts of (+)-epicatechin, 1-31 parts of 31 parts of procyanidine C, 14 parts of rutin, 4 parts of camphanol-3-O-rutinoside and 2 parts of isorhamnetin-3-O-rutinoside. The snow chrysanthemum is Changbai Mountain snow chrysanthemum. Animal experiments show that the refined component can significantly reduce the content of total cholesterol and triglyceride in serum of a high-fat model rat, the specific component with blood fat regulating activity is prepared from Changbai Mountain snow chrysanthemum, and a new choice is provided for non-drug intervention of dyslipidemia.

Stabilized oils including an edible oil and an antioxidant composition comprising α-lipoic acid and least one of ascorbic acid, ascorbyl palmitate, green tea extract, lecithin, and rosemary extract or at least one of 1,2,4-benzenetriol, carnosic acid, dihydromyricetin, dihydrorobinetin, epigallocatechin, gallic acid, 3-hydroxytyrosol, myricetin, and nepodin, and methods of preparing such stabilized edible oils. The stabilized oils may have an Oxidative Stability Index (“OSI”) at 110° C. of at least 30 hours.

This invention relates to the field of carbon nanotube technology, specifically to a surface-modified carbon nanotube, its preparation method, and its application. The preparation method of the surface-modified carbon nanotube involves first acid-treating the carbon nanotubes to obtain pretreated carbon nanotubes, then surface-modifying them with a silane coupling agent to obtain mercapto-modified carbon nanotubes, and finally modifying them with an epoxy group GA-HMDA synthesized from gallic acid and 4,4'-diaminodicyclohexylmethane to obtain surface-modified carbon nanotubes with good dispersibility and improved mechanical properties of composite materials.

The invention discloses a wear-resistant photo-thermal super-hydrophobic coating and a preparation method thereof.The preparation method comprises the steps that 1, after bamboo powder is subjected to alkali treatment and drying, high-temperature carbonization treatment is conducted under the hydrothermal condition, and carbonized bamboo powder is obtained; (2) dissolving gallic acid and cerous nitrate in an ethanol-water mixed solvent, carrying out a complexation reaction under a weakly alkaline condition to form a metal-polyphenol network precursor solution, and depositing the metal-polyphenol network precursor solution on the surface of the pretreated substrate under a hydrothermal condition to form a metal-polyphenol network layer; and (3) dispersing the carbonized bamboo powder and a fluorine-containing silane modifier in an organic solvent to prepare a hydrophobic modified dispersion liquid, spraying the hydrophobic modified dispersion liquid on the surface of the metal-polyphenol network layer, and performing drying and thermocuring treatment to obtain the wear-resistant photo-thermal super-hydrophobic coating.

This document describes antiperspirant compositions comprising an antiperspirant. The antiperspirant comprises optionally substituted benzenepropenoic acid. Optionally substituted benzenepropenoic acid, optionally combined with an ester of gallic acid, is also described. Methods and uses of the antiperspirant compositions and antiperspirants, for example, to reduce or prevent sweating, are also described.

The present application belongs to the field of food science and technology, and particularly relates to a method for separating and purifying walnut male flower polyphenols based on macroporous adsorption resin and application. Research shows that the X-5 type resin has the best performance in adsorbing and desorbing walnut male flower polyphenols, the adsorption process conforms to the Temkin isothermal model and the pseudo-second-order kinetic model, indicating that it is a spontaneous exothermic physical adsorption process. After process optimization (80% ethanol, 2 BV / h flow rate, 10 BV elution volume), the polyphenol content is significantly improved. The purified product detects 26 kinds of phenolic acid compounds and 22 kinds of flavonoids, the main components are astragalin, isquercitrin, protocatechuic acid, gallic acid and quercetin, accounting for 89.91% of the total phenol content. The antioxidant activity of the purified polyphenol extract is significantly enhanced, and it has obvious bacteriostatic effect on Staphylococcus aureus. The present application provides a theoretical basis for the high-value utilization of walnut male flower resources and its application in the fields of food and health care.

The invention belongs to the technical field of preparation of non-woven fabrics, and discloses a polyethylene fiber non-woven fabric as well as a preparation method and application thereof. The polyethylene fiber non-woven fabric is prepared from a gel spinning solution through differential electrostatic spinning; the gel spinning solution contains polyethylene, white oil and gallic acid and is prepared under the action of supercritical carbon dioxide. The preparation method comprises the following steps: 1) mixing polyethylene, white oil and gallic acid, introducing supercritical carbon dioxide to form a gel spinning solution, and cooling to obtain a colloid; 2) processing the obtained colloid on a screw type differential electrostatic spinning device to obtain a non-woven fabric; (3) carrying out cold pressing and stretching on the obtained non-woven fabric, then shaping, carrying out ultrasonic extraction, drying and removing an extracting agent; and 4) stretching and hot-pressing the non-woven fabric obtained in the step 3) again to obtain the polyethylene fiber non-woven fabric. The prepared non-woven fabric is smooth in surface, free of defects such as obvious holes and adjustable in fiber morphology.