409 results about "Gallic acid" patented technology

The invention provides a composition for promoting hair regeneration after chemotherapy as well as a preparation method and application thereof, and belongs to the technical field of medicines. The preparation method comprises the following steps: modifying the surface of a gold nanocage with polydopamine, loading the modified gold nanocage on an exosome, complexing magnesium ions and zinc ions to prepare a modified exosome, preparing a nano drug-loaded liposome from curcumin, resveratrol and epigallocatechin gallate, mixing the nano drug-loaded liposome with the modified exosome to prepare a multi-layer liposome, and preparing the multi-layer liposome from the nano drug-loaded liposome. And mixing with a penetration enhancer, and adding into a temperature-sensitive hydrogel system to prepare the composition for promoting hair regeneration after chemotherapy. The composition for promoting hair regeneration after chemotherapy has a good transdermal absorption promoting effect, can slowly release drugs, promotes hair follicles to be converted from a resting stage to a growing stage under the synergistic effect of the drugs, regulates and controls multiple pathways (such as anti-apoptosis, angiogenesis promotion and anti-inflammation) at the same time, is matched with a complex pathological mechanism of hair regeneration after chemotherapy, and can promote hair regeneration after chemotherapy. Wide application prospects are realized.

The invention discloses a tightening and whitening composition containing EGCG (epigallocatechin gallate) as well as a preparation method and application of the tightening and whitening composition, and relates to the technical field of cosmetics. The invention provides a tightening and whitening composition containing EGCG (epigallocatechin gallate). The tightening and whitening composition is prepared from the following components in parts by weight: 0.1 to 2 parts of an epigallocatechin gallate nano composition, 0.05 to 0.5 part of a nucleic acid tetrahedron and 0.5 to 5 parts of glassine. When the EGCG nano composition, the nucleic acid tetrahedron and the glassine are cooperatively used, the stability of a formula can be improved, meanwhile, the EGCG can be accurately released to an epidermal layer due to the enzyme-responsive degradation characteristic (such as matrix metalloproteinase MMP-2 triggered depolymerization) of the nucleic acid tetrahedron, and the glassine is released after deeply penetrating into a corium layer along with a nucleic acid tetrahedron carrier, so that the EGCG can be accurately released to the epidermal layer. The synergistic effects of the three components on whitening and tightening are better exerted.

The invention discloses a beta-glucuronidase inhibitor composition as well as a preparation method and application thereof. The composition is prepared from the following substances: ursolic acid, procyanidine, icariin, curcumin, epigallocatechin gallate and glycyrrhetinic acid. The beta-glucuronidase inhibitor composition has a broad-spectrum and good inhibition effect, the preparation method is simple, large-scale production is easy, and the inhibitor with a natural source is higher in use compliance, lower in toxic and side effects and more suitable for developing intestinal health products and has an application prospect.

The invention relates to the technical field of hydrogel, in particular to a preparation method and application of EGCG-mediated hydrogel, a lysozyme solution is heated under the acidic condition to form lysozyme amyloid fibrils LAFs, EGCG is dissolved in a buffer solution and mixed with the LAFs solution obtained in the step 1 in proportion to form an LAFs-EGCG compound, and the EGCG-mediated hydrogel is prepared. The chitosan CS is dissolved in an acetic acid buffer solution, glutaraldehyde is added to serve as a cross-linking agent, the mixture is mixed with the LAFs-EGCG compound obtained in the step 2 and stirred, the composite hydrogel is formed, the concentration of EGCG is 0.2-1.0 wt%, the concentration of LAFs is 5 wt%, the concentration of chitosan is 2 wt%, the pH value of the lysozyme solution in the step 1 is 2.0, the heating temperature is 77 DEG C, the heating time is 10 hours, the concentration of EGCG in the step 2 is 0.4-0.8 wt%, and the pH value of the lysozyme solution in the step 2 is 1.5-2.5. In the step 3, the concentration of glutaraldehyde is 2%, the storage modulus G'of the hydrogel is 325-480 Pa, the hardness is 2176.71 g, and the bacteriostasis rate on staphylococcus aureus and salmonella exceeds 95%.

The invention discloses a method for detecting antioxidants and polyphenols in food by constructing a colorimetric sensing array based on monatomic iron nano-enzyme, and belongs to the field of nanotechnology and colorimetric sensing. The traditional monatomic nano enzyme shows limited enzyme-like activity and substrate specificity, and is difficult to meet the comprehensive requirements of detecting various antioxidants and polyphenols in food. In the research, a novel nano-enzyme system (sdsFeN (at) G) of monatomic iron nano-enzyme is developed. The SdsFeN (at) G shows excellent enzymatic activity, and a three-channel colorimetric sensing array is constructed by utilizing inhibition of different antioxidants and polyphenols on oxidation of three chromogenic substrates, so that simple, convenient and reliable identification and detection of five substances (tert-butylhydroquinone, butylated hydroxyanisole, propyl gallate, catechol and hydroquinone) in food are realized.

The invention relates to the technical field of food fresh-keeping materials, in particular to a chitosan-curcumin nano-composite fresh-keeping agent and a preparation method thereof.The chitosan-curcumin nano-composite fresh-keeping agent comprises nano-particles of a chitosan-sodium alginate-oxidized sodium alginate interpenetrating network structure, according to the nanoparticles, protonated amino groups of chitosan and carboxyl groups of sodium alginate form a polyelectrolyte compound core, aldehyde groups of oxidized sodium alginate and amino groups of chitosan are subjected to a Schiff base reaction to form a chemical cross-linked network, and zinc ions, amino groups of chitosan, carboxyl groups of sodium alginate and carboxyl groups of oxidized sodium alginate form coordination cross-linking; curcumin and epigallocatechin gallate form a compound through a hydrogen bond and a hydrophobic effect, the compound is embedded in an interpenetrating network structure, beta-diketone groups of curcumin and zinc ions form chelating coordination, a chitosan-sodium alginate-oxidized sodium alginate ternary interpenetrating network is constructed, and the chitosan-sodium alginate-oxidized sodium alginate ternary interpenetrating network structure is formed. The stability is improved by utilizing the synergistic effect of triple mechanisms of electrostatic interaction, Schiff base chemical bonds and zinc ion coordination.

The invention discloses injectable hydrogel for photo-thermal adjuvant therapy of periodontitis and a preparation method, and belongs to the technical field of high polymer material preparation, the preparation method comprises the following steps: reacting MXene dispersion liquid with epigallocatechin gallate and MgSO4; then sequentially carrying out ultrasonic treatment, centrifugation, washing and freeze-drying to obtain a multifunctional nanosheet MP-Mg; adding the multifunctional nanosheet MP-Mg into an oxidized gellan gum aqueous solution, and carrying out a mixed reaction to obtain a solution A; mixing the quaternary ammonium salt chitosan aqueous solution and the carboxymethyl chitosan aqueous solution in equal volume, and reacting to obtain a solution B; and mixing the solution A and the solution B in equal volume for reaction. The hydrogel prepared by the preparation method disclosed by the invention has injectability, photo-thermal responsiveness, biological membrane penetrability, synergistic antibacterial property and long-acting anti-inflammatory property, and an innovative and practical photo-thermal adjuvant therapy platform is provided for clinical treatment of periodontitis.

The invention discloses a method for biosynthesizing epigallocatechin gallate glucoside, and belongs to the technical field of biocatalytic synthesis. According to the method, a sucrose phosphorylase mutant is adopted as a catalyst, the sucrose phosphorylase mutant is subjected to single-point mutation or combined mutation on the basis of an amino acid sequence SEQ ID NO.1, and the enzyme activity of the sucrose phosphorylase is improved through mutation; the mutant is utilized to realize efficient catalytic synthesis of epigallocatechin gallate glucoside, and in the whole catalytic process, the synthesis method is mild in condition, simple to operate, short in reaction time and high in catalytic efficiency, and has a good application prospect.

The invention relates to the technical field of green building materials, in particular to phase-change energy-storage thermal insulation mortar and a preparation method of the phase-change energy-storage thermal insulation mortar. 25 to 40 parts of methyl palmitate; 120 to 180 parts of hydrophobic perlite; 8 to 15 parts of expanded graphite; 3-6 parts of phosphorus sheet-shaped aluminum nitride; 180 to 250 parts of sulphoaluminate cement; 60 to 100 parts of volcanic rock micro powder; 0.3 to 0.8 part of hydroxypropyl methyl cellulose; 0.6 to 1.2 parts of a polycarboxylic acid water reducing agent; 2 to 4 parts of nano aluminum oxide; 0.8 to 1.5 parts of propyl gallate; and 1-2 parts of zinc borate. Through the proportion design of the antioxidant flame-retardant microcapsules and the lightweight composite aggregate, the problems of poor thermal conductivity and insufficient durability of a traditional phase change material are solved. Through phase change material loading, interface modification and multi-component cooperative regulation, the thermal insulation performance, energy storage efficiency and structural stability are remarkably improved, and the material is suitable for the fields of building energy saving, intelligent temperature control and the like.

A nutraceutical composition, consisting of Nicotinamide Mononucleotide in a range 250-1000 mg, Spermidine in a range 0.5-10 mg, Rhodiola Rosea in a range 200-600 mg, Cacao in a range 1000-10,000 mg, L-Theanine in a range 50-200 mg, Glucosamine in a range 500-3000 mg, and Hyaluronic acid in a range 50-240 mg, or consisting of Epigallocatechin-3-gallate in a range 100-500 mg, Quercetin in a range 250-1000 mg, Resveratrol in a range 150-1000 mg, Sulforaphane in a range 1-50 mg, and Calcium Alphaketoglutarate in a range 300-2000 mg, or consisting of Microdose Lithium in a range 1-5 mg, Trimethylglycine in a range 500-2000 mg, Glutathione in a range 250-1000 mg, Fisetin in a range 100-1000 mg, Urolithin A in a range 250-2000 mg, Sodium Butyrate in a range 100-3000 mg, Berberine in a range 500-1500 mg, Apigenin in a range 50-500 mg, Cinnamon in a range 1000-6000 mg, and Malate in a range 1000-6000 mg.

The invention discloses a preparation method and application of a targeted delivery system of a metal polyphenol nano system. The invention discloses a targeted delivery system of a metal polyphenol nano system, and a preparation method of the targeted delivery system comprises the following steps: taking the metal polyphenol nano system formed based on epigallocatechin gallate and iron ions as a carrier, and loading fucoxanthin to prepare fucoxanthin nano particles with active oxygen response characteristics; then, after chondroitin sulfate capable of targeting macrophages and (5-carboxyl amyl) triphenyl phosphorus bromide capable of targeting mitochondria are coupled, the fucoxanthin delivery system with the active oxygen response characteristic and the targeting characteristic is further prepared through a double emulsion anti-solvent evaporation method. The system can realize release of fucoxanthin under stimulation of active oxygen, and realizes aggregation of a targeted delivery system in mitochondria of a specific inflammation site. The carrying system can effectively improve or relieve the inflammatory bowel disease, and the raw materials used in the carrying system are low in cost, the preparation conditions are mild, and large-scale production is easy.

The invention provides a bacteriostatic PET (polyethylene terephthalate) coiled material as well as a preparation method and application thereof, and belongs to the technical field of high polymer materials, the bacteriostatic PET coiled material is prepared from the following raw materials: PET, nano titanium dioxide, nano talcum powder, a compatilizer, an antioxidant, a lubricant and a modified composite bacteriostatic agent; the compatilizer is an ethylene-methyl acrylate-glycidyl methacrylate random terpolymer and / or an ethylene-acrylic ester-maleic anhydride random terpolymer, and the compatilizer is an ethylene-methyl acrylate-glycidyl methacrylate random terpolymer and / or an ethylene-acrylic ester-maleic anhydride random terpolymer; the lubricant is one or a mixture of two of pentaerythritol stearate, erucyl amide, polyethylene wax, polyvinyl alcohol and ethylene bis stearamide; the modified composite bacteriostatic agent is prepared from catechin gallate, epsilon-polylysine hydrochloride and modified porous zinc oxide. The prepared antibacterial PET coiled material can be used for packaging materials of packaging boxes, lunch boxes, cup covers, trays and the like, and has good mechanical properties such as bending strength and impact strength and excellent antibacterial performance.

The invention discloses a composition containing a polypeptide exosome and application of the composition in preparation of a product with skin repair ability, and particularly relates to the technical field of biology, the composition comprises polypeptide-exosome composite nanoparticles, and a polypeptide containing a GRGDS motif and an umbilical cord Wharton's jelly exosome are covalently crosslinked; the lipid double-layer coating layer comprises phosphatidylcholine, cholesterol and PEG-2000, and the molar ratio of the phosphatidylcholine to the cholesterol to the PEG-2000 is 5: 3: 2; the synergist is prepared from 0.1 to 5 percent of epicatechin gallate and 2 to 8 percent of recombinant collagen III oligopeptide. The nano-liposome is prepared through microfluidic self-assembly and a film hydration-ultrasonic intercalation method, and can be loaded on a degradable microneedle patch, so that targeted slow release of a wound part is realized. Through the synergistic effect of targeted delivery, oxidation resistance and collagen regeneration, the skin repair efficiency is remarkably improved, and the healing time is shortened.

The present invention provides a conjugate comprising: (a) a CNS targeting ligand, (b) a hydrophilic polymer of polyethylene glycol (PEG), polylactic acid (PLA), polylactic acid-co-glycolic acid (PLGA), or glucan, and (c) a flavonoid. The present invention also provides a micelle nanoparticle composition comprising: (a) an outer shell comprising the conjugate, optionally (b) an inner shell comprising oligomeric (-)-epigallocatechin gallate (OEGCG), and optionally (c) a CNS disease treatment molecule encapsulated in the inner shell. The invention also provides a method of treating a CNS disease by administering to a subject an effective amount of a nanoparticle composition of the invention. The CNS targeting ligand targets a CNS tissue and delivers an active ingredient to the CNS tissue for treating a CNS pathological condition.

The invention discloses an anti-aging composition, a preparation method and application of the anti-aging composition in skin aging resistance, belongs to the technical field of cosmetics, and aims at solving the problems that in related technologies, anti-aging cosmetics are instable in functional components, and the skin aging resistance of transdermal absorbability and functional component combination needs to be further improved. The anti-aging composition is prepared from the following components in percentage by total weight of the composition: 10 to 20 percent of an anti-aging functional composition and 80 to 90 percent of an auxiliary material matrix, the composition with the anti-aging effect is prepared from the following main components: ascorbyl tetraisopalmitate, epigallocatechin gallate, hydroxytyrosol, a calendula extract, curcumin, resveratrol and glutathione. The anti-aging composition prepared by the invention has good stability, transdermal absorbability and capability of improving skin aging resistance.

The invention discloses a bio-based flame-retardant composition and application thereof in preparation of a polylactic acid composite material, and belongs to the technical field of polylactic acid composite materials. The bio-based flame-retardant composition comprises phosphorylated chitosan and M-EGCG, M is a transition metal element, and M-EGCG is a complex of epigallocatechin gallate EGCG and a transition metal ion; wherein the mass ratio of the M-EGCG to the phosphorylated chitosan is 1: (1-5). When the bio-based flame-retardant composition is used for preparing the polylactic acid composite material, the flame retardant property of the polylactic acid composite material can be improved, and the mechanical property of the polylactic acid material can be maintained.

The invention discloses a catechin-chitosan oligosaccharide-nano selenium composite material as well as a preparation method and application thereof, and belongs to the technical field of biomass nano materials. The preparation method of the catechin-chitosan oligosaccharide-nano selenium composite material comprises the following steps: firstly, mixing an aqueous solution of sodium selenite and an aqueous solution of epigallocatechin gallate according to the molar ratio of 1: (10-25), and stirring; the catechin-chitosan oligosaccharide-nano-selenium composite material is prepared by adding the catechin into sodium selenite, then adding chitosan oligosaccharide and water, and reacting to obtain the catechin-chitosan oligosaccharide-nano-selenium composite material, the final concentration of the sodium selenite in the reaction system is 1mM, and the final concentration of the chitosan oligosaccharide in percentage by mass is 1-2%. The composite material provided by the invention has relatively excellent antibacterial activity, is easy to clean, natural and environment-friendly, the preservation effect of the composite material applied to the berry fruits is superior to the effect of chitosan under the same concentration, and reference is provided for application ways and product forms such as preservation or packaging of the berry fruits.

The invention discloses double gel loaded with active substances as well as a preparation method and application of the double gel, and belongs to the technical field of medical dressings. The double gel is composed of a water phase and an oil phase, the water phase comprises oxidized sodium alginate and carboxymethyl chitosan, and the oil phase comprises glycerol monolaurate and camellia oil. Through the synergistic effect of a water phase and an oil phase, a stable double-gel system is formed, hydrophilic epigallocatechin gallate and lipophilic curcumin are loaded, and primary encapsulation of active substances is achieved. According to the double gel loaded with the active substance and the preparation method and application thereof, the double gel has excellent mechanical stability and gel performance, can achieve efficient delivery of the active substance, and has good biocompatibility and application prospects; effective treatment is expected to be achieved in acute burn and scald wound repair, theoretical basis and technical support are provided for application of the double gel in the fields of wound repair and medical cosmetology, and the double gel has the potential of replacing a traditional dressing and becoming a new generation of functional medical dressing.

The invention discloses functional recombinant soybean protein isolate emulsion gel as well as a preparation method and application thereof, and belongs to the technical field of soybean protein processing. The preparation method comprises the following steps: recombining three main components, namely soybean lipophilic protein, glycinin and beta-conglycinin, in soybean protein isolate (SPI) according to a certain compounding ratio, and carrying out combined modification on the recombined SPI by virtue of modification means such as ultrasonic treatment, heat treatment, magnetic field and enzyme crosslinking; the recombined SPI emulsion is subjected to micronization treatment by adopting high-pressure microjet homogenization treatment, and then the emulsion is jointly induced to be gelatinized by utilizing acid and salt ions and transglutaminase, so that the preparation efficiency, the structural strength and the stability of the emulsion gel are improved; two polyphenols, namely epigallocatechin gallate and quercetin, are co-embedded in an interface and an oil phase of the emulsion gel, so that the bioaccessibility and antioxidant activity of the polyphenols are improved, and the emulsion gel is endowed with functionality. The prepared emulsion gel can be widely applied to processing of functional food.

The invention discloses a preparation method of an environment-friendly water-based rubber protective film, and belongs to the technical field of rubber chemical modification. Comprising the following steps: mixing butadiene styrene rubber and nitrile rubber according to a mass ratio of 3: 1 to prepare an emulsion with the solid content of 40-50%, adding nano silicon dioxide and a silane coupling agent, and reacting at 50-60 DEG C for 2-3 hours to obtain a silane modified rubber emulsion; the preparation method comprises the following steps: preparing sodium alginate into a 2-3% aqueous solution, adding tributyl citrate and nano-zinc oxide, and carrying out ultrasonic dispersion for 30 minutes to obtain a composite cross-linking agent solution; dissolving chitosan in an acetic acid solution, adding propyl gallate and nano montmorillonite, and uniformly stirring and mixing to obtain a functional additive solution; adding the composite cross-linking agent solution and the functional additive solution into the modified rubber emulsion; by optimizing a formula system and a preparation process, the problems that an existing water-based protective film is poor in stability, low in drying speed, insufficient in water resistance and difficult to consider both flexibility and adhesive force are solved.

The invention discloses application of EGCG (epigallocatechin gallate) in preparation of feed for reducing mutton smell of Hu sheep, and belongs to the technical field of livestock and poultry feed. By adding epigallocatechin gallate into the Hu sheep feed, the proportion of muscle fatty acid of the Hu sheep can be reduced, specifically, the proportion of heptadecanoic acid and stearic acid is reduced so as to reduce the mutton smell of the Hu sheep, and the growth performance is not affected. Meanwhile, the raw materials of the prepared feed have universality, the peanut vines, the hybrid pennisetum alopecuroides, the garlic skin and the like are regional high-yield coarse feed, and the source of nutritional ingredients of daily ration is not limited; eGCG powder can be directly added into an existing feed production line, equipment does not need to be transformed, and good application prospects are achieved.

The invention discloses a special diet and a preparation process thereof, and the special diet comprises the following raw materials: 500-600 parts of a red date concentrated solution, 350-400 parts of purified water, 40-60 parts of collagen peptide, 4-6 parts of lycium ruthenicum primary pulp, 0.5-1.5 parts of donkey-hide gelatin oligopeptide powder, 0.5-1.5 parts of longan powder, 3-5 parts of gamma-aminobutyric acid essence, 0.5-1.5 parts of elastin peptide, 0.5-1.5 parts of cubilose peptide, and 0.5-1.5 parts of collagen tripeptide. And 0.5 to 1.5 parts of epigallocatechin gallate. According to the special diet disclosed by the invention, the matching of the red date concentrated solution and the lycium ruthenicum primary pulp not only provides abundant natural antioxidant substances, but also enhances the blood replenishing and beautifying functions of the product, and the combination of the collagen peptide, the elastin peptide and the collagen tripeptide provides multi-level nourishing protection and the like for skin and joint health. The whole preparation process is accurate and controllable in technological parameters, high in production efficiency and suitable for large-scale production, and the obtained product has the remarkable characteristics of being fine and smooth in taste, definite in effect and good in stability and can meet the diversified requirements of different people for functional dietary supplements.

The invention discloses a bionic self-crimping material and application in the nerve field, and relates to the technical field of nano materials. The preparation method comprises the following steps: firstly, carrying out ultraviolet photopolymerization on acrylic acid and acrylic acid-N-hydroxysuccinimide, adding chitosan and glutaraldehyde to form hydrogel, and introducing epigallocatechin gallate into a chitosan-acrylic acid network. The material is rapidly and autonomously curled into a tube shape after being in contact with wet nerves, glutaraldehyde is directionally and orderly diffused by adopting a three-channel micro-fluidic chip, and the fineness is improved, so that the matching degree of nerve broken ends with different thicknesses is increased; the surface active groups of the material and the natural component chitosan cooperate to realize suture-free fixation; the plant phenol antioxidant removes free radicals at nerve injury parts; the degradation period is synchronous with natural healing of nerves, and secondary operation for taking out is not needed. The electroneurographic signals using the material are transmitted more smoothly, the target muscle atrophy degree is reduced, and the limb movement function is recovered to be close to the normal level.

A preparation method of antibacterial hydrogel with enhanced antioxidant activity and NIR / pH double responsiveness comprises the following steps: firstly, preparing hollow copper sulfide nanoparticles, then dispersing the hollow copper sulfide nanoparticles into a chitosan solution to prepare the chitosan solution containing the hollow copper sulfide nanoparticles, and then adding the hollow copper sulfide nanoparticles into the chitosan solution to prepare the antibacterial hydrogel with enhanced antioxidant activity and NIR / pH double responsiveness. And sequentially adding a cross-linking agent epigallocatechin gallate (EGCG) solution and a 3-formyl phenylboronic acid solution (3-FPBA), and carrying out cross-linking, so as to obtain the antibacterial hydrogel with enhanced antioxidant activity and NIR / pH double responsiveness. The hydrogel is used for wound dressings in biomedical engineering materials. The preparation method is simple, the preparation process is green and safe, higher solid-like performance is shown, meanwhile, excellent injectability is kept, and great advantages can be achieved in the bacterial wound infection healing process.

The invention discloses hydrogel for periodontitis as well as a preparation method and application thereof, and relates to the technical field of medicines. The hydrogel disclosed by the invention is prepared from composite silver nanoparticles, phenylboronic acid grafted modified natural polymers, polyvinyl alcohol and epigallocatechin gallate, the composite silver nanoparticles comprise polydopamine, epigallocatechin gallate and a silver simple substance; the natural polymer contains a six-membered ring unit, and the six-membered ring unit contains a group which can be oxidized into an aldehyde group. The hydrogel can adapt to the oral environment, responsively releases silver and epigallocatechin gallate under ROS stimulation, has excellent anti-inflammatory and bactericidal effects, is good in photo-thermal activity, can cooperate with the photo-thermal effect to efficiently remove dental plaque, also has the effects of promoting M2 polarization and promoting alveolar bone regeneration, and is especially suitable for treatment of periodontitis.

The invention provides a mineralized gel type physalis alkekengi leavening agent and application thereof in preparation of physalis alkekengi tofu. The method comprises the following steps: firstly, forming an EGCG-Ca < 2 + > complex from epigallocatechin gallate and tricalcium phosphate in soybean clear water, inducing TCP nanosheets to be self-assembled, and interpenetrating with a soybean protein network to construct a mineralized gel skeleton; the mineralized gel type sour slurry leavening agent is prepared by firstly preparing a skeleton, then immobilizing lactic acid bacteria in micropores of the skeleton and finally performing electrostatic grafting on soybean peptide, so that the gel strength, the water binding capacity, the flavor and the like of sour slurry bean curds are improved, and the nutrition and the quality of the bean curds are further improved.

The invention relates to a multifunctional hemostatic sponge as well as a preparation method and application thereof. The hemostatic sponge comprises a matrix formed by cross-linking methylacryloylated collagen and nano-hydroxyapatite modified by epigallocatechin gallate, the mass ratio of the methacrylated collagen to the nano-hydroxyapatite modified by the epigallocatechin gallate is (2 to 30): 1. By combining ColMA and HAP coated EGCG and optimizing the proportion, the obtained hemostatic sponge has a good collagenase degradation resisting effect and hemostatic, anti-inflammatory and antibacterial effects, tissue regeneration and repair can be promoted, the use comfort of a patient is higher, and the treatment effect is better.

The invention relates to a composite binder and a preparation method thereof, an electrode plate and a secondary battery, and the preparation method of the composite binder comprises the following steps: providing a colloidal fluorine-containing polymer which comprises one or more of a homopolymer, a copolymer and a terpolymer formed by polymerization units, the polymerization unit comprises one or more of tetrafluoroethylene, chlorotrifluoroethylene, perfluoroalkyl vinyl ether and hexafluoropropylene; a solution of a substance containing a catechol structure is provided, the substance containing the catechol structure comprises one or more of dopamine, epicatechin, epicatechin gallate, epigalloyl catechin, epigalloyl catechin gallate and derivatives of the dopamine, the epicatechin, the epicatechin gallate, the epigalloyl catechin gallate and the derivatives of the dopamine, the epicatechin, the epicatechin gallate, the epigalloyl catechin gallate and the derivatives of the epigalloyl catechin gallate, and the solution is alkaline; the method comprises the following steps: mixing a colloidal fluorine-containing polymer with a solution of a substance containing a catechol structure to obtain a mixed solution, reacting the mixed solution under a dark condition, co-condensing the reacted solution to obtain a precipitate, floating the precipitate on the surface of the solution, and containing the composite binder.

The invention relates to the technical field of compositions of high-molecular compounds, and particularly discloses a preparation method of a sodium caseinate-epigallocatechin gallate-iron ion ternary complex as well as a product and application thereof. The preparation method comprises the following steps: S1, adding EGCG (epigallocatechin gallate) into an SC solution, and stirring in a shading environment to obtain a binary compound; s2, adding a FeCl3. 6H2O solution into the binary compound, and stirring in a shading environment to obtain a ternary compound; wherein in the ternary complex, the mass ratio of SC to EGCG to Fe < 3 + > is (10-14): 1: (2-4). According to the preparation method disclosed by the invention, the stable ternary complex can be prepared, the ternary complex utilizes the metal phenolic network to modify the sodium caseinate, and a high internal phase emulsion formed after the sodium caseinate is loaded with the beta-carotene can show excellent stability and relatively high encapsulation efficiency, so that the bioavailability of the beta-carotene can be remarkably improved.

The invention relates to a collagen peptide composition and application thereof in recovering or promoting collagen content. The collagen peptide composition comprises Galvor E and a collagen peptide. Specifically, the collagen peptide composition further comprises at least one of aronia melanocarpa fruit concentrated solution and EGCG (epigallocatechin gallate). Compared with a single drug, the collagen peptide composition can more effectively recover the content of various collagens in skin cells, and also reduces the expression of senescence genes, so that the skin elasticity is recovered, and the skin elasticity is improved. The senescence is delayed.