345 results about "Gallic acid" patented technology

The invention provides a composition for promoting hair regeneration after chemotherapy as well as a preparation method and application thereof, and belongs to the technical field of medicines. The preparation method comprises the following steps: modifying the surface of a gold nanocage with polydopamine, loading the modified gold nanocage on an exosome, complexing magnesium ions and zinc ions to prepare a modified exosome, preparing a nano drug-loaded liposome from curcumin, resveratrol and epigallocatechin gallate, mixing the nano drug-loaded liposome with the modified exosome to prepare a multi-layer liposome, and preparing the multi-layer liposome from the nano drug-loaded liposome. And mixing with a penetration enhancer, and adding into a temperature-sensitive hydrogel system to prepare the composition for promoting hair regeneration after chemotherapy. The composition for promoting hair regeneration after chemotherapy has a good transdermal absorption promoting effect, can slowly release drugs, promotes hair follicles to be converted from a resting stage to a growing stage under the synergistic effect of the drugs, regulates and controls multiple pathways (such as anti-apoptosis, angiogenesis promotion and anti-inflammation) at the same time, is matched with a complex pathological mechanism of hair regeneration after chemotherapy, and can promote hair regeneration after chemotherapy. Wide application prospects are realized.

The invention discloses a tightening and whitening composition containing EGCG (epigallocatechin gallate) as well as a preparation method and application of the tightening and whitening composition, and relates to the technical field of cosmetics. The invention provides a tightening and whitening composition containing EGCG (epigallocatechin gallate). The tightening and whitening composition is prepared from the following components in parts by weight: 0.1 to 2 parts of an epigallocatechin gallate nano composition, 0.05 to 0.5 part of a nucleic acid tetrahedron and 0.5 to 5 parts of glassine. When the EGCG nano composition, the nucleic acid tetrahedron and the glassine are cooperatively used, the stability of a formula can be improved, meanwhile, the EGCG can be accurately released to an epidermal layer due to the enzyme-responsive degradation characteristic (such as matrix metalloproteinase MMP-2 triggered depolymerization) of the nucleic acid tetrahedron, and the glassine is released after deeply penetrating into a corium layer along with a nucleic acid tetrahedron carrier, so that the EGCG can be accurately released to the epidermal layer. The synergistic effects of the three components on whitening and tightening are better exerted.

The invention relates to the technical field of food fresh-keeping materials, in particular to a chitosan-curcumin nano-composite fresh-keeping agent and a preparation method thereof.The chitosan-curcumin nano-composite fresh-keeping agent comprises nano-particles of a chitosan-sodium alginate-oxidized sodium alginate interpenetrating network structure, according to the nanoparticles, protonated amino groups of chitosan and carboxyl groups of sodium alginate form a polyelectrolyte compound core, aldehyde groups of oxidized sodium alginate and amino groups of chitosan are subjected to a Schiff base reaction to form a chemical cross-linked network, and zinc ions, amino groups of chitosan, carboxyl groups of sodium alginate and carboxyl groups of oxidized sodium alginate form coordination cross-linking; curcumin and epigallocatechin gallate form a compound through a hydrogen bond and a hydrophobic effect, the compound is embedded in an interpenetrating network structure, beta-diketone groups of curcumin and zinc ions form chelating coordination, a chitosan-sodium alginate-oxidized sodium alginate ternary interpenetrating network is constructed, and the chitosan-sodium alginate-oxidized sodium alginate ternary interpenetrating network structure is formed. The stability is improved by utilizing the synergistic effect of triple mechanisms of electrostatic interaction, Schiff base chemical bonds and zinc ion coordination.

The invention discloses injectable hydrogel for photo-thermal adjuvant therapy of periodontitis and a preparation method, and belongs to the technical field of high polymer material preparation, the preparation method comprises the following steps: reacting MXene dispersion liquid with epigallocatechin gallate and MgSO4; then sequentially carrying out ultrasonic treatment, centrifugation, washing and freeze-drying to obtain a multifunctional nanosheet MP-Mg; adding the multifunctional nanosheet MP-Mg into an oxidized gellan gum aqueous solution, and carrying out a mixed reaction to obtain a solution A; mixing the quaternary ammonium salt chitosan aqueous solution and the carboxymethyl chitosan aqueous solution in equal volume, and reacting to obtain a solution B; and mixing the solution A and the solution B in equal volume for reaction. The hydrogel prepared by the preparation method disclosed by the invention has injectability, photo-thermal responsiveness, biological membrane penetrability, synergistic antibacterial property and long-acting anti-inflammatory property, and an innovative and practical photo-thermal adjuvant therapy platform is provided for clinical treatment of periodontitis.

The invention discloses a method for biosynthesizing epigallocatechin gallate glucoside, and belongs to the technical field of biocatalytic synthesis. According to the method, a sucrose phosphorylase mutant is adopted as a catalyst, the sucrose phosphorylase mutant is subjected to single-point mutation or combined mutation on the basis of an amino acid sequence SEQ ID NO.1, and the enzyme activity of the sucrose phosphorylase is improved through mutation; the mutant is utilized to realize efficient catalytic synthesis of epigallocatechin gallate glucoside, and in the whole catalytic process, the synthesis method is mild in condition, simple to operate, short in reaction time and high in catalytic efficiency, and has a good application prospect.

The invention relates to the technical field of green building materials, in particular to phase-change energy-storage thermal insulation mortar and a preparation method of the phase-change energy-storage thermal insulation mortar. 25 to 40 parts of methyl palmitate; 120 to 180 parts of hydrophobic perlite; 8 to 15 parts of expanded graphite; 3-6 parts of phosphorus sheet-shaped aluminum nitride; 180 to 250 parts of sulphoaluminate cement; 60 to 100 parts of volcanic rock micro powder; 0.3 to 0.8 part of hydroxypropyl methyl cellulose; 0.6 to 1.2 parts of a polycarboxylic acid water reducing agent; 2 to 4 parts of nano aluminum oxide; 0.8 to 1.5 parts of propyl gallate; and 1-2 parts of zinc borate. Through the proportion design of the antioxidant flame-retardant microcapsules and the lightweight composite aggregate, the problems of poor thermal conductivity and insufficient durability of a traditional phase change material are solved. Through phase change material loading, interface modification and multi-component cooperative regulation, the thermal insulation performance, energy storage efficiency and structural stability are remarkably improved, and the material is suitable for the fields of building energy saving, intelligent temperature control and the like.

A nutraceutical composition, consisting of Nicotinamide Mononucleotide in a range 250-1000 mg, Spermidine in a range 0.5-10 mg, Rhodiola Rosea in a range 200-600 mg, Cacao in a range 1000-10,000 mg, L-Theanine in a range 50-200 mg, Glucosamine in a range 500-3000 mg, and Hyaluronic acid in a range 50-240 mg, or consisting of Epigallocatechin-3-gallate in a range 100-500 mg, Quercetin in a range 250-1000 mg, Resveratrol in a range 150-1000 mg, Sulforaphane in a range 1-50 mg, and Calcium Alphaketoglutarate in a range 300-2000 mg, or consisting of Microdose Lithium in a range 1-5 mg, Trimethylglycine in a range 500-2000 mg, Glutathione in a range 250-1000 mg, Fisetin in a range 100-1000 mg, Urolithin A in a range 250-2000 mg, Sodium Butyrate in a range 100-3000 mg, Berberine in a range 500-1500 mg, Apigenin in a range 50-500 mg, Cinnamon in a range 1000-6000 mg, and Malate in a range 1000-6000 mg.

The invention discloses a preparation method and application of a targeted delivery system of a metal polyphenol nano system. The invention discloses a targeted delivery system of a metal polyphenol nano system, and a preparation method of the targeted delivery system comprises the following steps: taking the metal polyphenol nano system formed based on epigallocatechin gallate and iron ions as a carrier, and loading fucoxanthin to prepare fucoxanthin nano particles with active oxygen response characteristics; then, after chondroitin sulfate capable of targeting macrophages and (5-carboxyl amyl) triphenyl phosphorus bromide capable of targeting mitochondria are coupled, the fucoxanthin delivery system with the active oxygen response characteristic and the targeting characteristic is further prepared through a double emulsion anti-solvent evaporation method. The system can realize release of fucoxanthin under stimulation of active oxygen, and realizes aggregation of a targeted delivery system in mitochondria of a specific inflammation site. The carrying system can effectively improve or relieve the inflammatory bowel disease, and the raw materials used in the carrying system are low in cost, the preparation conditions are mild, and large-scale production is easy.

The invention discloses a composition containing a polypeptide exosome and application of the composition in preparation of a product with skin repair ability, and particularly relates to the technical field of biology, the composition comprises polypeptide-exosome composite nanoparticles, and a polypeptide containing a GRGDS motif and an umbilical cord Wharton's jelly exosome are covalently crosslinked; the lipid double-layer coating layer comprises phosphatidylcholine, cholesterol and PEG-2000, and the molar ratio of the phosphatidylcholine to the cholesterol to the PEG-2000 is 5: 3: 2; the synergist is prepared from 0.1 to 5 percent of epicatechin gallate and 2 to 8 percent of recombinant collagen III oligopeptide. The nano-liposome is prepared through microfluidic self-assembly and a film hydration-ultrasonic intercalation method, and can be loaded on a degradable microneedle patch, so that targeted slow release of a wound part is realized. Through the synergistic effect of targeted delivery, oxidation resistance and collagen regeneration, the skin repair efficiency is remarkably improved, and the healing time is shortened.

The invention discloses a bio-based flame-retardant composition and application thereof in preparation of a polylactic acid composite material, and belongs to the technical field of polylactic acid composite materials. The bio-based flame-retardant composition comprises phosphorylated chitosan and M-EGCG, M is a transition metal element, and M-EGCG is a complex of epigallocatechin gallate EGCG and a transition metal ion; wherein the mass ratio of the M-EGCG to the phosphorylated chitosan is 1: (1-5). When the bio-based flame-retardant composition is used for preparing the polylactic acid composite material, the flame retardant property of the polylactic acid composite material can be improved, and the mechanical property of the polylactic acid material can be maintained.

The invention discloses a catechin-chitosan oligosaccharide-nano selenium composite material as well as a preparation method and application thereof, and belongs to the technical field of biomass nano materials. The preparation method of the catechin-chitosan oligosaccharide-nano selenium composite material comprises the following steps: firstly, mixing an aqueous solution of sodium selenite and an aqueous solution of epigallocatechin gallate according to the molar ratio of 1: (10-25), and stirring; the catechin-chitosan oligosaccharide-nano-selenium composite material is prepared by adding the catechin into sodium selenite, then adding chitosan oligosaccharide and water, and reacting to obtain the catechin-chitosan oligosaccharide-nano-selenium composite material, the final concentration of the sodium selenite in the reaction system is 1mM, and the final concentration of the chitosan oligosaccharide in percentage by mass is 1-2%. The composite material provided by the invention has relatively excellent antibacterial activity, is easy to clean, natural and environment-friendly, the preservation effect of the composite material applied to the berry fruits is superior to the effect of chitosan under the same concentration, and reference is provided for application ways and product forms such as preservation or packaging of the berry fruits.

The invention discloses double gel loaded with active substances as well as a preparation method and application of the double gel, and belongs to the technical field of medical dressings. The double gel is composed of a water phase and an oil phase, the water phase comprises oxidized sodium alginate and carboxymethyl chitosan, and the oil phase comprises glycerol monolaurate and camellia oil. Through the synergistic effect of a water phase and an oil phase, a stable double-gel system is formed, hydrophilic epigallocatechin gallate and lipophilic curcumin are loaded, and primary encapsulation of active substances is achieved. According to the double gel loaded with the active substance and the preparation method and application thereof, the double gel has excellent mechanical stability and gel performance, can achieve efficient delivery of the active substance, and has good biocompatibility and application prospects; effective treatment is expected to be achieved in acute burn and scald wound repair, theoretical basis and technical support are provided for application of the double gel in the fields of wound repair and medical cosmetology, and the double gel has the potential of replacing a traditional dressing and becoming a new generation of functional medical dressing.

The invention discloses functional recombinant soybean protein isolate emulsion gel as well as a preparation method and application thereof, and belongs to the technical field of soybean protein processing. The preparation method comprises the following steps: recombining three main components, namely soybean lipophilic protein, glycinin and beta-conglycinin, in soybean protein isolate (SPI) according to a certain compounding ratio, and carrying out combined modification on the recombined SPI by virtue of modification means such as ultrasonic treatment, heat treatment, magnetic field and enzyme crosslinking; the recombined SPI emulsion is subjected to micronization treatment by adopting high-pressure microjet homogenization treatment, and then the emulsion is jointly induced to be gelatinized by utilizing acid and salt ions and transglutaminase, so that the preparation efficiency, the structural strength and the stability of the emulsion gel are improved; two polyphenols, namely epigallocatechin gallate and quercetin, are co-embedded in an interface and an oil phase of the emulsion gel, so that the bioaccessibility and antioxidant activity of the polyphenols are improved, and the emulsion gel is endowed with functionality. The prepared emulsion gel can be widely applied to processing of functional food.

The invention discloses a preparation method of an environment-friendly water-based rubber protective film, and belongs to the technical field of rubber chemical modification. Comprising the following steps: mixing butadiene styrene rubber and nitrile rubber according to a mass ratio of 3: 1 to prepare an emulsion with the solid content of 40-50%, adding nano silicon dioxide and a silane coupling agent, and reacting at 50-60 DEG C for 2-3 hours to obtain a silane modified rubber emulsion; the preparation method comprises the following steps: preparing sodium alginate into a 2-3% aqueous solution, adding tributyl citrate and nano-zinc oxide, and carrying out ultrasonic dispersion for 30 minutes to obtain a composite cross-linking agent solution; dissolving chitosan in an acetic acid solution, adding propyl gallate and nano montmorillonite, and uniformly stirring and mixing to obtain a functional additive solution; adding the composite cross-linking agent solution and the functional additive solution into the modified rubber emulsion; by optimizing a formula system and a preparation process, the problems that an existing water-based protective film is poor in stability, low in drying speed, insufficient in water resistance and difficult to consider both flexibility and adhesive force are solved.

The invention discloses application of EGCG (epigallocatechin gallate) in preparation of feed for reducing mutton smell of Hu sheep, and belongs to the technical field of livestock and poultry feed. By adding epigallocatechin gallate into the Hu sheep feed, the proportion of muscle fatty acid of the Hu sheep can be reduced, specifically, the proportion of heptadecanoic acid and stearic acid is reduced so as to reduce the mutton smell of the Hu sheep, and the growth performance is not affected. Meanwhile, the raw materials of the prepared feed have universality, the peanut vines, the hybrid pennisetum alopecuroides, the garlic skin and the like are regional high-yield coarse feed, and the source of nutritional ingredients of daily ration is not limited; eGCG powder can be directly added into an existing feed production line, equipment does not need to be transformed, and good application prospects are achieved.

The invention discloses a special diet and a preparation process thereof, and the special diet comprises the following raw materials: 500-600 parts of a red date concentrated solution, 350-400 parts of purified water, 40-60 parts of collagen peptide, 4-6 parts of lycium ruthenicum primary pulp, 0.5-1.5 parts of donkey-hide gelatin oligopeptide powder, 0.5-1.5 parts of longan powder, 3-5 parts of gamma-aminobutyric acid essence, 0.5-1.5 parts of elastin peptide, 0.5-1.5 parts of cubilose peptide, and 0.5-1.5 parts of collagen tripeptide. And 0.5 to 1.5 parts of epigallocatechin gallate. According to the special diet disclosed by the invention, the matching of the red date concentrated solution and the lycium ruthenicum primary pulp not only provides abundant natural antioxidant substances, but also enhances the blood replenishing and beautifying functions of the product, and the combination of the collagen peptide, the elastin peptide and the collagen tripeptide provides multi-level nourishing protection and the like for skin and joint health. The whole preparation process is accurate and controllable in technological parameters, high in production efficiency and suitable for large-scale production, and the obtained product has the remarkable characteristics of being fine and smooth in taste, definite in effect and good in stability and can meet the diversified requirements of different people for functional dietary supplements.

The invention discloses a bionic self-crimping material and application in the nerve field, and relates to the technical field of nano materials. The preparation method comprises the following steps: firstly, carrying out ultraviolet photopolymerization on acrylic acid and acrylic acid-N-hydroxysuccinimide, adding chitosan and glutaraldehyde to form hydrogel, and introducing epigallocatechin gallate into a chitosan-acrylic acid network. The material is rapidly and autonomously curled into a tube shape after being in contact with wet nerves, glutaraldehyde is directionally and orderly diffused by adopting a three-channel micro-fluidic chip, and the fineness is improved, so that the matching degree of nerve broken ends with different thicknesses is increased; the surface active groups of the material and the natural component chitosan cooperate to realize suture-free fixation; the plant phenol antioxidant removes free radicals at nerve injury parts; the degradation period is synchronous with natural healing of nerves, and secondary operation for taking out is not needed. The electroneurographic signals using the material are transmitted more smoothly, the target muscle atrophy degree is reduced, and the limb movement function is recovered to be close to the normal level.

The invention provides a mineralized gel type physalis alkekengi leavening agent and application thereof in preparation of physalis alkekengi tofu. The method comprises the following steps: firstly, forming an EGCG-Ca < 2 + > complex from epigallocatechin gallate and tricalcium phosphate in soybean clear water, inducing TCP nanosheets to be self-assembled, and interpenetrating with a soybean protein network to construct a mineralized gel skeleton; the mineralized gel type sour slurry leavening agent is prepared by firstly preparing a skeleton, then immobilizing lactic acid bacteria in micropores of the skeleton and finally performing electrostatic grafting on soybean peptide, so that the gel strength, the water binding capacity, the flavor and the like of sour slurry bean curds are improved, and the nutrition and the quality of the bean curds are further improved.

The invention relates to the technical field of compositions of high-molecular compounds, and particularly discloses a preparation method of a sodium caseinate-epigallocatechin gallate-iron ion ternary complex as well as a product and application thereof. The preparation method comprises the following steps: S1, adding EGCG (epigallocatechin gallate) into an SC solution, and stirring in a shading environment to obtain a binary compound; s2, adding a FeCl3. 6H2O solution into the binary compound, and stirring in a shading environment to obtain a ternary compound; wherein in the ternary complex, the mass ratio of SC to EGCG to Fe < 3 + > is (10-14): 1: (2-4). According to the preparation method disclosed by the invention, the stable ternary complex can be prepared, the ternary complex utilizes the metal phenolic network to modify the sodium caseinate, and a high internal phase emulsion formed after the sodium caseinate is loaded with the beta-carotene can show excellent stability and relatively high encapsulation efficiency, so that the bioavailability of the beta-carotene can be remarkably improved.

The invention discloses a polydopamine-tea polyphenol coated copper manganese oxide composite nano-enzyme as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials. According to the invention, a DA-Cu (II)-EGCG (epigallocatechin gallate) complex is formed by virtue of chelation of main components of dopamine and tea polyphenol, namely epigallocatechin gallate, and copper ions; potassium permanganate is introduced for oxidative polymerization to obtain the polydopamine-tea polyphenol / copper manganese oxide organic-inorganic hybrid nano composite material, the nano composite material is monodisperse nano particles, the average particle size is about 80 nm, the nano composite material shows excellent nano enzyme catalytic activity, active oxygen free radicals can be effectively removed, and the nano composite material can be used for preparing nano-enzyme. The material has good photo-thermal conversion performance under near-infrared light, and shows excellent photo-thermal and photodynamic synergistic antibacterial effects. The preparation method disclosed by the invention is simple, mild, environment-friendly, low in cost and convenient for batch production.

The invention relates to the technical field of wet tissues, in particular to an all-cotton wet tissue which comprises a base material and a wet tissue immersion liquid, wherein the wet tissue immersion liquid contains 0.1-0.4 wt% of a thickening agent, 0.1-2 wt% of a surfactant, 0.14-0.28 wt% of a pH regulator, 0.01-0.35 wt% of an environment-friendly non-irritant bactericide, 0.1-1.5 wt% of propylene glycol, 0.01-0.2 wt% of essence and the balance of deionized water; the preparation process of the environment-friendly non-irritating bactericide comprises the following steps: dissolving propyl gallate in ethanol, adding into a tea polyphenol-PEG acrylate modified quaternary ammonium salt modified carboxymethyl chitosan solution, adding a chitosan sulfate catalyst, adjusting the pH value to 5-7, and stirring and reacting in a constant-temperature water bath at 60-80 DEG C for 4-8 hours to obtain the environment-friendly non-irritating bactericide. According to the all-cotton wet tissue, the environment-friendly non-irritating bactericide is added into the wet tissue immersion liquid, so that the all-cotton wet tissue has very good environment-friendly non-irritating bactericidal performance.

The invention provides hydrogel, preparation of the hydrogel and medical dressing containing the hydrogel, CMC-PBA and HA-DA are used as hydrogel matrixes and are connected through boric acid ester bonds, and copper nano-enzyme (Cu NCs) chelated by EGCG is added into the hydrogel matrixes, so that the hydrogel (EGCG-Cu NPs) loaded with the copper nano-enzyme (injectable) is obtained. Wherein the CMC-PBA is a product obtained by reacting carboxymethyl chitosan (CMC) with carboxyl activated 4-carboxyphenylboronic acid (PBA), and the HA-DA is a product obtained by reacting carboxyl activated hyaluronic acid (HA) with dopamine hydrochloride (DA). The hydrogel can deeply promote wound recovery through in-vivo use, has good antioxidant activity and antibacterial activity, has extremely high active oxygen removal performance on necrotic cells of the wound, greatly accelerates the healing speed of the wound, brings clinical welfare to the wound, especially a chronic disease wound, and promotes the development of chronic wound diseases.

The invention relates to the technical field of pig feeds, and particularly discloses a special compound feed for weaning sows, the feed comprises a functional additive, the functional additive comprises the following raw materials in parts by weight: 1-3 parts of a plant extract compound, 2-5 parts of conjugated linoleic acid, 0.0003-0.0005 part of selenomethionine, 0.15-0.35 part of vitamin E, and 0.15-0.3 part of vitamin C; the plant extract compound is prepared from the following components: astragalus polysaccharide, icariin, epigallocatechin gallate and a carrier, and the mass ratio of the astragalus polysaccharide to the icariin to the epigallocatechin gallate is 1 to (1 to 4) to (0.2 to 0.8). The special compound feed for the weaned sows is used for feeding the weaned sows through a scientific and reasonable formula, can promote follicular development of the sows after weaning, improve the oestrus rate and reduce the proportion of non-oestrus sows, and can solve the problem of slow ovarian function recovery of the sows in summer high-temperature seasons.

The invention discloses a preparation method and application of a collagen packaging film, and belongs to the technical field of bio-based food packaging materials.The method comprises the steps that animal-derived collagen is dissolved in an acetic acid solution with the pH ranging from 3.5 to 4.5 to form a solution with the concentration ranging from 3% to 5%; sequentially adding genipin accounting for 15-25% of the dry weight of the collagen and cellulose nanowhiskers accounting for 8-12% of the dry weight of the collagen, and carrying out a cross-linking reaction at 35-40 DEG C to construct a three-dimensional network structure; then soaking treatment is performed by adopting a 70-80% ethanol solution containing 0.5-1.5% of propyl gallate, and the surface hydrophobicity is improved through specific binding of phenolic hydroxyl groups and collagen hydrophobic regions; and finally, carrying out vacuum drying and 60-70% humidity environment balance treatment to obtain the degradable membrane material with high mechanical strength and moderate waterproofness. The preparation method is particularly suitable for fresh-keeping packaging of chilled meat products, and the shelf life of food can be effectively prolonged while the biodegradability of materials is kept.

The invention provides a composition containing exosome, which is prepared from the following components in parts by weight: 10 to 20 parts of exosome, 5 to 15 parts of extract, 0.3 to 0.5 part of antioxidant and 0.05 to 0.1 part of preservative, the extract is a mixture of 3-8 parts of aloe extract, 1-5 parts of camellia flower extract and 1-3 parts of cranberry extract; the preservative is one or more of benzoic acid, salicylic acid, boric acid and sorbic acid; the antioxidant is propyl gallate. When the composition is applied to an anti-aging product, the temperature sensing effect and the DPPH free radical scavenging rate are obviously improved.

The invention relates to a tea-collagen composition with whitening and anti-aging effects as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The invention provides a tea-collagen composition with whitening and anti-aging effects. The tea-collagen composition is prepared from epigallocatechin gallate, collagen IV and collagen VII. According to the invention, the safety and anti-oxidation characteristics of EGCG are utilized, and collagen IV and collagen VII are combined to stabilize a cell basement membrane in the form of'glue ', so that the collagen is strengthened, and further the whitening and anti-aging effects are achieved. Meanwhile, experiments prove that the EGCG can synergistically improve the elastase inhibition ratio of the collagen IV and the collagen VII, conversely, the collagen IV and the collagen VII can also synergistically improve the tyrosinase inhibition ratio of the EGCG, and the tea-collagen composition has the whitening and anti-aging effects due to the complementation of the EGCG, the collagen IV and the collagen VII.

The invention relates to the technical field of food processing safety and environmental pollution control, in particular to a natural compound preparation with a synergistic formaldehyde removal function and a preparation method and application thereof. The natural compound preparation is prepared from the following raw materials in percentage by mass: 5%-10% of carnosine, 0.5%-2% of epigallocatechin gallate, 0.05%-0.2% of edible essence, 10%-20% of a surfactant and the balance of a solvent, and the total percentage is 100%. The invention aims to reduce the exposure risk of specific groups such as chefs and guarantee the health level of the specific groups, the main component carnosine is dipeptide which can be used as a food additive and has good antioxidant activity, and amino in the structure of the carnosine can be subjected to Michael addition reaction with carbonyl of aldehydes. The epigallocatechin gallate is a common polyphenol substance, and phenolic hydroxyl groups in the epigallocatechin gallate can be reacted with aldehydes to capture and remove the aldehydes.

The application discloses a gastric cancer immunotherapy efficacy prediction biopsy sample MHC-II expression kit and belongs to the field of kit preparation, and particularly relates to a preparation method of an antigen repair solution, which is prepared by mixing citric acid, sodium citrate, an additive and pure water, and the additive comprises a glucose amido polyether derivative and a propyl gallate / calcium ion complex. The gastric cancer immunotherapy efficacy prediction biopsy sample MHC-II expression kit is composed of the antigen repair solution; the kit comprises the following components in parts by mass: 20-30 parts of a dewaxing solution, 10-20 parts of the antigen repair solution, 2-10 parts of sheep serum, 10-20 parts of an enhancing solution, 15-25 parts of an antibody, 5-15 parts of a staining solution and 10-20 parts of a mounting agent. The gastric cancer immunotherapy efficacy prediction biopsy sample MHC-II expression kit provided by the application has high sensitivity and high specificity.

The invention discloses a preparation method of curcumin, and belongs to the technical field of natural product extraction. The method comprises the following steps: firstly, adopting a modified deep-eutectic solvent into which propyl gallate is introduced as an extraction medium, and realizing high-selectivity extraction of curcumin through a special molecular structure of the modified deep-eutectic solvent; then the ultrasonic-microwave coupling technology is combined, so that the extraction efficiency is remarkably improved; finally, the modified molecularly imprinted polymer with magnetism is used for precise purification, the material has the specific recognition capacity and the rapid magnetic separation characteristic, polyethylene glycol is introduced to serve as a pore-foaming agent, and more active sites are provided for adsorption of curcumin molecules. According to the method disclosed by the invention, through collaborative innovation of all links, the whole process optimization from extraction to purification is realized, the product purity and the extraction efficiency are remarkably improved, the energy consumption and the solvent pollution are greatly reduced, and a reliable solution is provided for industrial production of the high-quality curcumin.

This invention belongs to the field of food processing technology, specifically relating to a walnut protein isolate-xanthan gum-epigallocatechin gallate ternary complex, emulsion, its preparation method, and its application. The walnut protein isolate-xanthan gum-epigallocatechin gallate ternary complex in the composite emulsion provided by this invention exhibits reduced particle size, enhanced electrostatic repulsion, and the absence of uneven clumps and particles. The elasticity and viscosity of the composite emulsion are significantly enhanced, and the complex demonstrates comprehensive environmental stability over a wide range of pH, salt concentration, and temperature conditions.