248 results about "Gallic acid" patented technology

The invention relates to the technical field of food fresh-keeping materials, in particular to a chitosan-curcumin nano-composite fresh-keeping agent and a preparation method thereof.The chitosan-curcumin nano-composite fresh-keeping agent comprises nano-particles of a chitosan-sodium alginate-oxidized sodium alginate interpenetrating network structure, according to the nanoparticles, protonated amino groups of chitosan and carboxyl groups of sodium alginate form a polyelectrolyte compound core, aldehyde groups of oxidized sodium alginate and amino groups of chitosan are subjected to a Schiff base reaction to form a chemical cross-linked network, and zinc ions, amino groups of chitosan, carboxyl groups of sodium alginate and carboxyl groups of oxidized sodium alginate form coordination cross-linking; curcumin and epigallocatechin gallate form a compound through a hydrogen bond and a hydrophobic effect, the compound is embedded in an interpenetrating network structure, beta-diketone groups of curcumin and zinc ions form chelating coordination, a chitosan-sodium alginate-oxidized sodium alginate ternary interpenetrating network is constructed, and the chitosan-sodium alginate-oxidized sodium alginate ternary interpenetrating network structure is formed. The stability is improved by utilizing the synergistic effect of triple mechanisms of electrostatic interaction, Schiff base chemical bonds and zinc ion coordination.

The invention discloses injectable hydrogel for photo-thermal adjuvant therapy of periodontitis and a preparation method, and belongs to the technical field of high polymer material preparation, the preparation method comprises the following steps: reacting MXene dispersion liquid with epigallocatechin gallate and MgSO4; then sequentially carrying out ultrasonic treatment, centrifugation, washing and freeze-drying to obtain a multifunctional nanosheet MP-Mg; adding the multifunctional nanosheet MP-Mg into an oxidized gellan gum aqueous solution, and carrying out a mixed reaction to obtain a solution A; mixing the quaternary ammonium salt chitosan aqueous solution and the carboxymethyl chitosan aqueous solution in equal volume, and reacting to obtain a solution B; and mixing the solution A and the solution B in equal volume for reaction. The hydrogel prepared by the preparation method disclosed by the invention has injectability, photo-thermal responsiveness, biological membrane penetrability, synergistic antibacterial property and long-acting anti-inflammatory property, and an innovative and practical photo-thermal adjuvant therapy platform is provided for clinical treatment of periodontitis.

A nutraceutical composition, consisting of Nicotinamide Mononucleotide in a range 250-1000 mg, Spermidine in a range 0.5-10 mg, Rhodiola Rosea in a range 200-600 mg, Cacao in a range 1000-10,000 mg, L-Theanine in a range 50-200 mg, Glucosamine in a range 500-3000 mg, and Hyaluronic acid in a range 50-240 mg, or consisting of Epigallocatechin-3-gallate in a range 100-500 mg, Quercetin in a range 250-1000 mg, Resveratrol in a range 150-1000 mg, Sulforaphane in a range 1-50 mg, and Calcium Alphaketoglutarate in a range 300-2000 mg, or consisting of Microdose Lithium in a range 1-5 mg, Trimethylglycine in a range 500-2000 mg, Glutathione in a range 250-1000 mg, Fisetin in a range 100-1000 mg, Urolithin A in a range 250-2000 mg, Sodium Butyrate in a range 100-3000 mg, Berberine in a range 500-1500 mg, Apigenin in a range 50-500 mg, Cinnamon in a range 1000-6000 mg, and Malate in a range 1000-6000 mg.

The invention discloses functional recombinant soybean protein isolate emulsion gel as well as a preparation method and application thereof, and belongs to the technical field of soybean protein processing. The preparation method comprises the following steps: recombining three main components, namely soybean lipophilic protein, glycinin and beta-conglycinin, in soybean protein isolate (SPI) according to a certain compounding ratio, and carrying out combined modification on the recombined SPI by virtue of modification means such as ultrasonic treatment, heat treatment, magnetic field and enzyme crosslinking; the recombined SPI emulsion is subjected to micronization treatment by adopting high-pressure microjet homogenization treatment, and then the emulsion is jointly induced to be gelatinized by utilizing acid and salt ions and transglutaminase, so that the preparation efficiency, the structural strength and the stability of the emulsion gel are improved; two polyphenols, namely epigallocatechin gallate and quercetin, are co-embedded in an interface and an oil phase of the emulsion gel, so that the bioaccessibility and antioxidant activity of the polyphenols are improved, and the emulsion gel is endowed with functionality. The prepared emulsion gel can be widely applied to processing of functional food.

The invention discloses a bionic self-crimping material and application in the nerve field, and relates to the technical field of nano materials. The preparation method comprises the following steps: firstly, carrying out ultraviolet photopolymerization on acrylic acid and acrylic acid-N-hydroxysuccinimide, adding chitosan and glutaraldehyde to form hydrogel, and introducing epigallocatechin gallate into a chitosan-acrylic acid network. The material is rapidly and autonomously curled into a tube shape after being in contact with wet nerves, glutaraldehyde is directionally and orderly diffused by adopting a three-channel micro-fluidic chip, and the fineness is improved, so that the matching degree of nerve broken ends with different thicknesses is increased; the surface active groups of the material and the natural component chitosan cooperate to realize suture-free fixation; the plant phenol antioxidant removes free radicals at nerve injury parts; the degradation period is synchronous with natural healing of nerves, and secondary operation for taking out is not needed. The electroneurographic signals using the material are transmitted more smoothly, the target muscle atrophy degree is reduced, and the limb movement function is recovered to be close to the normal level.

The invention relates to the technical field of compositions of high-molecular compounds, and particularly discloses a preparation method of a sodium caseinate-epigallocatechin gallate-iron ion ternary complex as well as a product and application thereof. The preparation method comprises the following steps: S1, adding EGCG (epigallocatechin gallate) into an SC solution, and stirring in a shading environment to obtain a binary compound; s2, adding a FeCl3. 6H2O solution into the binary compound, and stirring in a shading environment to obtain a ternary compound; wherein in the ternary complex, the mass ratio of SC to EGCG to Fe < 3 + > is (10-14): 1: (2-4). According to the preparation method disclosed by the invention, the stable ternary complex can be prepared, the ternary complex utilizes the metal phenolic network to modify the sodium caseinate, and a high internal phase emulsion formed after the sodium caseinate is loaded with the beta-carotene can show excellent stability and relatively high encapsulation efficiency, so that the bioavailability of the beta-carotene can be remarkably improved.

The invention discloses a polydopamine-tea polyphenol coated copper manganese oxide composite nano-enzyme as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials. According to the invention, a DA-Cu (II)-EGCG (epigallocatechin gallate) complex is formed by virtue of chelation of main components of dopamine and tea polyphenol, namely epigallocatechin gallate, and copper ions; potassium permanganate is introduced for oxidative polymerization to obtain the polydopamine-tea polyphenol / copper manganese oxide organic-inorganic hybrid nano composite material, the nano composite material is monodisperse nano particles, the average particle size is about 80 nm, the nano composite material shows excellent nano enzyme catalytic activity, active oxygen free radicals can be effectively removed, and the nano composite material can be used for preparing nano-enzyme. The material has good photo-thermal conversion performance under near-infrared light, and shows excellent photo-thermal and photodynamic synergistic antibacterial effects. The preparation method disclosed by the invention is simple, mild, environment-friendly, low in cost and convenient for batch production.

The invention relates to the technical field of pig feeds, and particularly discloses a special compound feed for weaning sows, the feed comprises a functional additive, the functional additive comprises the following raw materials in parts by weight: 1-3 parts of a plant extract compound, 2-5 parts of conjugated linoleic acid, 0.0003-0.0005 part of selenomethionine, 0.15-0.35 part of vitamin E, and 0.15-0.3 part of vitamin C; the plant extract compound is prepared from the following components: astragalus polysaccharide, icariin, epigallocatechin gallate and a carrier, and the mass ratio of the astragalus polysaccharide to the icariin to the epigallocatechin gallate is 1 to (1 to 4) to (0.2 to 0.8). The special compound feed for the weaned sows is used for feeding the weaned sows through a scientific and reasonable formula, can promote follicular development of the sows after weaning, improve the oestrus rate and reduce the proportion of non-oestrus sows, and can solve the problem of slow ovarian function recovery of the sows in summer high-temperature seasons.

The invention provides a composition containing exosome, which is prepared from the following components in parts by weight: 10 to 20 parts of exosome, 5 to 15 parts of extract, 0.3 to 0.5 part of antioxidant and 0.05 to 0.1 part of preservative, the extract is a mixture of 3-8 parts of aloe extract, 1-5 parts of camellia flower extract and 1-3 parts of cranberry extract; the preservative is one or more of benzoic acid, salicylic acid, boric acid and sorbic acid; the antioxidant is propyl gallate. When the composition is applied to an anti-aging product, the temperature sensing effect and the DPPH free radical scavenging rate are obviously improved.

The invention relates to the technical field of food processing safety and environmental pollution control, in particular to a natural compound preparation with a synergistic formaldehyde removal function and a preparation method and application thereof. The natural compound preparation is prepared from the following raw materials in percentage by mass: 5%-10% of carnosine, 0.5%-2% of epigallocatechin gallate, 0.05%-0.2% of edible essence, 10%-20% of a surfactant and the balance of a solvent, and the total percentage is 100%. The invention aims to reduce the exposure risk of specific groups such as chefs and guarantee the health level of the specific groups, the main component carnosine is dipeptide which can be used as a food additive and has good antioxidant activity, and amino in the structure of the carnosine can be subjected to Michael addition reaction with carbonyl of aldehydes. The epigallocatechin gallate is a common polyphenol substance, and phenolic hydroxyl groups in the epigallocatechin gallate can be reacted with aldehydes to capture and remove the aldehydes.

The application discloses a gastric cancer immunotherapy efficacy prediction biopsy sample MHC-II expression kit and belongs to the field of kit preparation, and particularly relates to a preparation method of an antigen repair solution, which is prepared by mixing citric acid, sodium citrate, an additive and pure water, and the additive comprises a glucose amido polyether derivative and a propyl gallate / calcium ion complex. The gastric cancer immunotherapy efficacy prediction biopsy sample MHC-II expression kit is composed of the antigen repair solution; the kit comprises the following components in parts by mass: 20-30 parts of a dewaxing solution, 10-20 parts of the antigen repair solution, 2-10 parts of sheep serum, 10-20 parts of an enhancing solution, 15-25 parts of an antibody, 5-15 parts of a staining solution and 10-20 parts of a mounting agent. The gastric cancer immunotherapy efficacy prediction biopsy sample MHC-II expression kit provided by the application has high sensitivity and high specificity.

The invention discloses a preparation method of curcumin, and belongs to the technical field of natural product extraction. The method comprises the following steps: firstly, adopting a modified deep-eutectic solvent into which propyl gallate is introduced as an extraction medium, and realizing high-selectivity extraction of curcumin through a special molecular structure of the modified deep-eutectic solvent; then the ultrasonic-microwave coupling technology is combined, so that the extraction efficiency is remarkably improved; finally, the modified molecularly imprinted polymer with magnetism is used for precise purification, the material has the specific recognition capacity and the rapid magnetic separation characteristic, polyethylene glycol is introduced to serve as a pore-foaming agent, and more active sites are provided for adsorption of curcumin molecules. According to the method disclosed by the invention, through collaborative innovation of all links, the whole process optimization from extraction to purification is realized, the product purity and the extraction efficiency are remarkably improved, the energy consumption and the solvent pollution are greatly reduced, and a reliable solution is provided for industrial production of the high-quality curcumin.

This invention belongs to the field of food processing technology, specifically relating to a walnut protein isolate-xanthan gum-epigallocatechin gallate ternary complex, emulsion, its preparation method, and its application. The walnut protein isolate-xanthan gum-epigallocatechin gallate ternary complex in the composite emulsion provided by this invention exhibits reduced particle size, enhanced electrostatic repulsion, and the absence of uneven clumps and particles. The elasticity and viscosity of the composite emulsion are significantly enhanced, and the complex demonstrates comprehensive environmental stability over a wide range of pH, salt concentration, and temperature conditions.

The invention discloses a medicine lotus cell suspension factory system and method for directionally producing high-activity components based on a healthy target spot, and the system is characterized in that a health-oriented cell line design module, an intelligent scale culture module, a precise metabolism induction module and a targeted separation and product development module are in closed-loop linkage; and an innovative mode of reversely designing a production process from health requirements is realized. According to the method, aiming at specific targets of epidemic resistance, depression resistance, reproductive health and the like, a high-yield cell line is created through multi-omics analysis screening or gene editing, and large-scale culture is performed in an optimally controlled bioreactor; and the elicitor is utilized to accurately stimulate a metabolic pathway to directionally enrich high-value components such as liensinine, nuciferine, epigallocatechin gallate and the like. And finally, preparing a standardized extract by adopting a green extraction technology (such as ultrasonic extraction and supercritical CO2 extraction), wherein the standardized extract is used for functional foods, dietary supplements or medical products.

The invention relates to a mild anti-aging composition suitable for sensitive skin and application of the mild anti-aging composition, and belongs to the technical field of cosmetics. The invention provides a mild anti-aging composition suitable for sensitive skin, the composition is prepared by compounding a camellia nitidissima flower fermentation extract, hydrolyzed lupin protein, epigallocatechin gallate and phytol, the four components cooperate with each other to play a role, and on the premise that the skin barrier is not damaged, the anti-aging effect is good, and the anti-aging effect is good. The anti-aging composition can be used for softening skin touch, improving elasticity and fading deep wrinkles, can be used for remarkably improving the problems of skin sclerosis, elasticity loss and deep wrinkles caused by skin fibrosis, and is particularly suitable for sensitive people who cannot tolerate strong-irritation anti-aging components due to fragile skin barriers.

The invention belongs to the technical field of oil sludge separating agents, and particularly provides an oil sludge separating agent and an oil sludge separating method.The preparation method comprises the following steps that propylene glycol block polyether, a coagulant and an oil trapping agent are mixed and stirred, and the oil sludge separating agent is obtained; the preparation method of the oil trapping agent comprises the following steps: S01, taking polycaprolactone, adding acetone, and carrying out heating dispersion to obtain a solution A; s02, hydroxypropyl-beta-cyclodextrin and propyl gallate are taken, heated, added with water and stirred, then pH is adjusted, ethylenediamine disuccinic acid is added, stirring continues, and a solution B is obtained; and S03, dropwise adding the solution A into the solution B, maintaining stirring until the solution is completely mixed, then performing rotary evaporation, and collecting solid components, thereby obtaining the product. The total deoiling rate of the oil sludge treated by the oil sludge separating agent and the separation method is greater than or equal to 92.5%.

The invention provides a method for judging the grade of Zhenmei green tea based on chemical components and a regression equation, and belongs to the technical field of agricultural product quality detection.The method comprises the steps that data of four target chemical components in to-be-detected Zhenmei green tea is obtained, comprising 5-gallic quinic acid, epigallocatechin gallate, gallocatechin gallate and epicatechin gallate, and is prepared from 5-gallic quinic acid, epigallocatechin gallate, gallocatechin gallate and epicatechin gallate; the data of the target chemical components are input into a regression equation, a prediction grade value corresponding to the to-be-detected Zhenmei green tea is obtained through calculation, the four target chemical components are obtained through screening based on data of known different grade sample sets, and the prediction grade value of the to-be-detected Zhenmei green tea is obtained. The regression equation is obtained through ridge regression analysis training based on data and quality grades of four target chemical components of known different-grade sample sets. The method is used for solving the problem that the grade of tea is inaccurately judged through sense organs at present, and the Zhenmei green tea grade judgment method completely based on quantifiable chemical components is achieved.

The application belongs to the technical field of organic synthesis and particularly relates to a synthesis method of electronic-grade 2,3,4-trihydroxybenzophenone. The application comprises the following steps: catalytic reaction: taking water as a solvent, mixing water and a catalyst uniformly, adding pyrogallic acid, heating the system to 40-50 DEG C, continuously adding trichloromethylbenzene, performing insulation reaction, cooling the system to 10-15 DEG C after the reaction is completed, crystallizing and precipitating, and then filtering to obtain a crude wet product; purification treatment: removing impurities from the crude wet product to obtain the high-purity 2,3,4-trihydroxybenzophenone. The application does not need to react in an organic solvent system, is green and environmentally friendly, does not need nitrogen protection, has low production cost, and is suitable for industrialized processing and production, and the prepared 2,3,4-trihydroxybenzophenone has high purity and high yield.

The invention relates to an oral nutritional composition. More specifically, the invention provides an oral nutritional composition with an antioxidant function, which comprises vitamin C, vitamin E, lutein and epigallocatechin gallate (EGCG) which are combined according to a certain proportion.

The invention provides a biological slow-release fertilizer for slope corn planting and a preparation method thereof, and relates to the technical field of corn planting. The fertilizer is prepared from a straw fermentation material, humic acid, kieselguhr, a modified starch material, charcoal, expanded vermiculite, sodium alginate, magnesium sulfate, monopotassium phosphate, urea, ethylenediamine disuccinate trisodium salt and propyl gallate. The straw fermentation material is prepared by crushing straw, performing alkali treatment, inoculating aspergillus oryzae for fermentation, sterilizing, continuing to inoculate bacillus subtilis for fermentation and drying; the modified starch material is obtained by mixing a semi-gelatinized starch material and a completely gelatinized starch material. The method overcomes the defects in the prior art, prematurity of slope field corn planting is effectively promoted through adjustment and improvement of the fertilizer, water and soil loss during planting is prevented, and the effect of high-yield corn planting is achieved.

The invention discloses a preparation method and application of a functional tea extract, and aims to solve the problems that active ingredients are easy to oxidize and degrade and low in purity in existing tea leaf processing. Enzymatic browning is inhibited through liquid nitrogen quick-freezing pretreatment, the mass transfer efficiency is enhanced in combination with dynamic ultrasonic-assisted extraction, efficient enrichment is achieved by adopting a multi-stage membrane separation or resin purification technology, and the retention rate and purity of catechin substances (especially epigallocatechin gallate EGCG) are remarkably improved. According to the method, thermal degradation and oxidation loss are effectively reduced, and the obtained extract has excellent antioxidant and antibacterial properties and can be widely applied to the fields of functional food, health care products and the like.

The invention discloses a water-soluble diclazuril solution and a preparation method thereof, and belongs to the technical field of veterinary drug preparations, the water-soluble diclazuril solution comprises 10-30 g / L of diclazuril, 100-500 g / L of an organic solvent, 30-60 g / L of an amine organic base, 5-10 g / L of a surfactant, the balance of water for injection, 3-5 g / L of propyl gallate, and 10-15 g / L of a composite fermentation broth, the organic solvent comprises the following components in percentage by mass: 20-40% of N, N-dimethylformamide, 40-70% of propylene glycol and 10-20% of ethanol, and the compound fermentation liquor is a fermentation product obtained by fermenting a mixture of felwort and tamarind fruits with a compound microbial inoculant. The water-soluble diclazuril solution provided by the invention not only can effectively prevent and treat chicken coccidiosis, but also is beneficial to improving the weight gain rate of broiler chickens in the recovery process after infection, the preparation method is simple, the cost is low, the use mode is convenient and efficient, and the use value of the water-soluble diclazuril solution in the aspect of broiler chicken breeding is effectively improved.

The application provides a method for preparing epigallocatechin gallate (EGCG) by using a dynamic axial compression column. The method comprises the following steps: taking a tea polyphenol extract as a raw material, and separating and purifying EGCG by using a dynamic axial compression column. The method can safely and efficiently prepare high-purity EGCG.

This invention discloses a near-infrared light-exciteable composite nanosheet, its preparation method, and its applications, belonging to the field of biomedical technology. The method includes the following steps: mixing epigallocatechin gallate with a Ti3C2 nanosheet dispersion, ultrasonically reacting, adding silver salt, and continuing stirring in the dark; after the reaction is complete, washing and separating to obtain MXene-EGCG@Ag composite nanosheets. The composite nanosheets provided by this invention possess near-infrared light-exciteable properties and can be used to prepare medically acceptable dosage forms such as hydrogels for the treatment of periodontitis. The preparation method provided by this invention is simple, the raw materials are readily available, and it exhibits significant antibacterial and anti-inflammatory effects, enabling further widespread application.

The application belongs to the field of coordination chemistry and analytical sensing technology, and particularly relates to a Zn(II)-Tb(III) complex ratio fluorescence sensor and a preparation method and application thereof. The sensor is a double-metal coordination polymer formed by coordination of Zn(II) ions, Tb(III) ions, nitrogen-containing organic ligands and carboxylic acid organic ligands. Under excitation conditions, the sensor simultaneously generates an emission signal of ligand coordination with Zn(II) and a characteristic emission signal of Tb(III) ions, forming intrinsic double emission. By monitoring the fluorescence intensity ratio (I395 / I549) of the two characteristic emission peaks at 395 nm and 549 nm, ratio fluorescence detection of propyl gallate can be realized, and the detection limit is as low as 0.35 μM. The sensor of the application has a simple synthesis method, a rapid detection process, and realizes internal calibration by using a ratio signal, has strong anti-interference ability, and is suitable for detection of propyl gallate in edible oil and other actual samples.

The invention provides a pharmaceutical composition containing oridonin, a pharmaceutical preparation containing the oridonin and application of the pharmaceutical preparation. The pharmaceutical composition comprises the oridonin and epigallocatechin gallate. By taking breast cancer cells MCF-7 as an in-vitro experimental model, the invention finds that compared with a control group (single medication), the composition of oridonin serving as a main component in rabdosia rubescens and epigallocatechin gallate serving as a main component in polyphenols in tea leaves has the advantages that in a specific ratio range, the content of the oridonin serving as the main component in the rabdosia rubescens and the content of the epigallocatechin gallate serving as the main component in the polyphenols in the tea leaves can be greatly stronger proliferation inhibition activity is shown on breast cancer cells. The compound can generate a synergistic inhibition effect on cancer treatment, and is suitable for preparing antitumor drugs.

This rotigotine-containing adhesive patch comprises a support layer and an adhesive layer, wherein the adhesive layer contains: at least one selected from the group consisting of rotigotine and pharmaceutically acceptable salts of rotigotine; a rubber-based adhesive base; and an antioxidant. The antioxidant includes propyl gallate, ascorbyl palmitate, and sodium pyrosulfite.

The application relates to a high-antibacterial PETG composite material and a preparation method and application thereof, which comprises the following raw materials in parts by mass: 100 parts of PETG, 2-5 parts of a composite antibacterial agent, 3-10 parts of a silane coupling agent and 0.1-0.3 parts of an initiator; wherein the composite antibacterial agent is a combination of propyl gallate, hexamidine diisethionate and polyhexamethylene biguanide hydrochloride. The composite antibacterial agent can be stably combined with the PETG matrix through the action of the coupling agent and the initiator. The PETG composite material has both processing feasibility and long-acting antibacterial property through the synergistic action of the composite antibacterial agent, the coupling agent and the initiator.

The invention belongs to the technical field of functional food and active substance delivery, and relates to EGCG (epigallocatechin gallate) loaded protein-polysaccharide ternary composite nanoparticles and a preparation method thereof. Zein is used as carrier protein, Arabic gum is used as stable polysaccharide, and an anti-solvent precipitation method is combined with ultrasonic treatment to prepare the composite nanoparticles. The preparation method specifically comprises the following steps: dissolving zein in an ethanol water solution to form an organic phase, dissolving Arabic gum in a water phase, adding the water phase into the organic phase under a stirring condition, removing ethanol to obtain a zein-Arabic gum binary composite nanoparticle dispersion liquid, introducing EGCG, and carrying out ultrasonic-assisted loading and drying to obtain a target product. The encapsulation efficiency of the active substance is improved through the ultrasonic-anti-solvent synergistic effect, the thermal stability and storage stability of the system are improved, and the method is simple, good in repeatability and suitable for delivery of food-grade active ingredients.