465 results about "Adjuvant therapy" patented technology

The invention provides a multi-modal image analysis-based robot-assisted wound treatment method and system, and relates to the technical field of robots, and the method comprises the steps: collecting a multi-modal image of a to-be-treated wound, determining an image registration result, obtaining a wound region image through a multi-scale fusion algorithm and wound region segmentation, and carrying out the type classification of wound tissues. A wound tissue type classification result is obtained; performing surrounding shooting on a wound area to obtain a wound multi-view image, registering subsequent depth maps frame by frame by taking a first frame of depth map as a reference, accumulating point cloud data, determining a wound three-dimensional point cloud, generating a wound three-dimensional reconstruction result by combining a curved surface evolution algorithm, and determining a wound parameter measurement result; based on the wound tissue type classification result and the wound parameter measurement result, a robot path planning algorithm is adopted, the optimal movement track of the robot is generated, the movement parameters of the robot are adjusted in real time through a robot control algorithm of vision and force feedback, and wound adjuvant therapy is completed.

The invention provides an expectoration auxiliary control method and device. The method comprises the steps that audio signals of breathing sounds and cough sounds at multiple positions of the chest of a patient are collected through an audio sensor array, and a standardized audio feature data set is obtained through noise reduction, segmentation and feature extraction; a dynamic weighted graph model is constructed, and a random edge sampling algorithm and a parallel batch processing dynamic algorithm are combined to analyze and obtain a sputum viscosity index and a sputum distribution position map; based on the result, mapping the vibration parameter space into an unweighted disk diagram, and obtaining a personalized vibration treatment scheme by using a shortest path algorithm; in combination with the real-time breathing cycle of the patient, working parameters of the sound wave vibrator and the negative pressure suction device are synchronously controlled, and a coordinated and consistent multi-mode treatment execution instruction is obtained; and collecting real-time feedback data in treatment, and dynamically adjusting working parameters through reinforcement learning to obtain an optimized expectoration adjuvant therapy scheme. Intelligent adjustment can be achieved based on the real-time breathing state and sputum characteristics of the patient, the expectoration efficiency is improved, and discomfort of the patient is reduced.

The invention relates to the field of cubilose peptides, in particular to preparation and application of cubilose glycopeptides capable of preventing and assisting in treating gynecological inflammation and gastrointestinal inflammation. The invention provides cubilose glycopeptide which comprises cubilose peptide, sialylated O-glycan and sialylated N-glycan, and the cubilose peptide is connected with the sialylated O-glycan and / or the sialylated N-glycan. The cubilose glycopeptide provided by the invention has unique sialylated O-glycans and N-glycans, has unique biological activity and functions and synergistic effect compared with the cubilose glycopeptide without N-glycans or O-glycans and non-sialylated cubilose peptides, and forms and enhances the inhibition effect on pathogens and the antiviral effect; therefore, the compound has unique advantages in the aspect of preventing and treating related problems. The sialic acid binding type cubilose glycopeptide has stronger antibacterial activity, especially has an inhibition effect on pathogens such as candida albicans and helicobacter pylori, and also has an antiviral effect.

The invention discloses a multifunctional leg sleeve for auxiliary treatment of lower limb lymphedema, which comprises a leg sleeve body, a pressure sensing unit, a temperature and humidity sensing unit, an air bag pressure unit, a heating unit, an electrical stimulation unit, an impedance measuring unit and a portable force-electricity-heat cooperative intervention controller, the leg sleeve is characterized in that the pressure sensor and the temperature and humidity sensor monitor internal environment parameters of the leg sleeve body, drive the air bag pressure unit to perform self-adaptive pressurization, and drive the heating element and the electrical stimulation electrode to perform intelligent heating medicine application and muscle stimulation at the same time; the main control unit is driven to adjust the pressure, the temperature and the stimulation intensity of the air bag pressurizing unit, the heating unit and the electrical stimulation unit; in the wearing period, the device uploads data to a mobile phone and a cloud server terminal for data analysis, optimal pressure, temperature and electrical stimulation regulation prescriptions are provided for a user, and a good treatment effect is achieved.

The discovery and application of immune checkpoint inhibitors (ICI) have significantly promoted cancer treatment. However, the response rate is still low in gastrointestinal (GI) cancers. To explore novel adjuvant treatment options, we performed fecal microbiota transplantation (FMT) of healthy donors on 10 GI cancer patients with resistance to anti-PD-(L) 1 treatment. The combination of FMT and anti-PD1 treatment was well tolerated and no serious adverse reaction was observed. Two out of 10 patients restored clinical responsiveness to anti-PD1 after FMT. Clinical benefits were shown to be associated with better colonization of co-occurred immunogenic microbes from donors, alongside activated immune status reflected by the peripheral immune cell population. Moreover, we identified microbial signatures of ICI responsiveness and validated in an independent cohort. Our study demonstrates the feasibility of FMT as a potential adjuvant therapy for ICI irresponsive GI cancer patients and laid a foundation for LBP / consortia development to enhance ICI efficacy.

Devices, systems, and methods described in this disclosure can be used to deliver electroporation and adjunct therapies to treat anastomotic leaks and the resulting abscess cavities around the GI tract, within the thoracic cavity, and elsewhere within the human body. The thermal or non-thermal electroporation therapy can be delivered using the devices, systems, and methods described herein. In some embodiments, the electroporation energy is delivered to achieve sterilization and promote healing of spaces such as abscess cavities.

The invention discloses injectable hydrogel for photo-thermal adjuvant therapy of periodontitis and a preparation method, and belongs to the technical field of high polymer material preparation, the preparation method comprises the following steps: reacting MXene dispersion liquid with epigallocatechin gallate and MgSO4; then sequentially carrying out ultrasonic treatment, centrifugation, washing and freeze-drying to obtain a multifunctional nanosheet MP-Mg; adding the multifunctional nanosheet MP-Mg into an oxidized gellan gum aqueous solution, and carrying out a mixed reaction to obtain a solution A; mixing the quaternary ammonium salt chitosan aqueous solution and the carboxymethyl chitosan aqueous solution in equal volume, and reacting to obtain a solution B; and mixing the solution A and the solution B in equal volume for reaction. The hydrogel prepared by the preparation method disclosed by the invention has injectability, photo-thermal responsiveness, biological membrane penetrability, synergistic antibacterial property and long-acting anti-inflammatory property, and an innovative and practical photo-thermal adjuvant therapy platform is provided for clinical treatment of periodontitis.

The invention provides clinical gastrointestinal decompression equipment for the digestive system department, and belongs to the technical field of adjuvant therapy. Comprising a mounting mechanism; a connecting arm is fixedly connected to the front face of the mounting mechanism, a power mechanism is mounted on the side, away from the mounting mechanism, of the connecting arm through bolts, and a rail frame is fixedly mounted on the side, away from the mounting mechanism, of the power mechanism. Through the arrangement, the equipment can be installed on the side edge of a sickbed during use, can adapt to different occasions, can adjust the height to meet the requirements of different patients, realizes the transverse and longitudinal synchronous displacement of the massage mechanism on the abdomen of the patient through the motor driving of the power and linkage mechanism, is large in massage range and excellent in massage effect, can replace manual massage, is not influenced by the external environment, and is suitable for popularization and application. The massage decompression mechanism can be used for hot compress massage, the temperature can be adjusted, the pressure of the gastrointestinal tract is further relieved, and better treatment experience is brought to a patient.

The invention relates to the technical field of adjuvant therapy monitoring, in particular to an anorectal disease adjuvant therapy monitoring system and method based on a radix scrophulariae extract. The method comprises two stages of system initialization and adjuvant therapy monitoring, in the initialization stage, initialization setting is completed, and a dynamic monitoring code is generated to guarantee data transmission security; in the auxiliary treatment stage, baseline data are collected, abnormal values are removed, then personalized baselines are generated, the drug dosage and the release rate are adjusted according to the baseline data, meanwhile, pressure, temperature, blood flow and electrophysiological data are monitored in real time, key indexes are calculated, monitoring labels are generated, the physiological indexes are standardized, the treatment effect is comprehensively evaluated, and classification is conducted. The dynamic trend is analyzed by adopting a polynomial fitting method, an evaluation result is generated, the drug release rate and dosage are dynamically optimized in combination with real-time monitoring data and patient feedback, and fine treatment is further performed by adopting a feedback adjustment mechanism. According to the invention, efficient auxiliary treatment and intelligent monitoring of anorectal diseases are realized.

An embracing robot for adjuvant therapy of depression belongs to the crossing field of medical health and man-machine interaction and comprises a sensor module, a driving module, a control module, a feedback module, a touch module and a software module. Through the sponge-cotton-sponge interlayer design, the comfortable touch feeling is provided, the warmth and softness of human hugging are simulated, and the emotional satisfaction of a user is enhanced. By combining a sensor and an algorithm, the robot can monitor the embracing strength and duration of the user in real time, the embracing strength and mode are intelligently adjusted, and personalized emotion support is provided. The embracing experience every time is not monotonous due to the randomly changing embracing postures and diversified action modes, the sense of reality and the sense of naturalness are increased, and the mechanical experience is avoided. Through pacifying actions, anxiety and pressure of a user are effectively relieved, treatment of depression is assisted, and emotional comfort is provided.

The invention relates to the technical field of rehabilitation assistance, in particular to an intelligent breathing assistance system for lung rehabilitation, comprising: a breathing part, the breathing part comprising a breathing cylinder, the breathing cylinder comprising a fixed cylinder and a folding cylinder, the fixed cylinder being internally provided with an auxiliary assembly; the wearing part comprises a chest cover and an abdomen cover, a connecting channel and a vibration channel are formed in the chest cover, an air bag is embedded in the abdomen cover, and a vibration phlegm eliminating assembly is arranged in the vibration channel; the thoracico-abdominal movement mode recognition unit is used for detecting a breathing mode of a user; the lung function detection unit is used for calculating and detecting the tidal volume of a user; the personalized training control unit is used for adjusting breathing resistance according to the tidal volume and breathing modes, according to different breathing modes of users, the breathing assisting force is adjusted through kinetic energy of gas exhaled by the users, key parameters such as the tidal volume and the recovery condition are monitored in real time, the lung rehabilitation effect is further improved, and the lung rehabilitation effect is improved. And more accurate and effective breathing adjuvant therapy is realized.

The invention provides a bifidobacterium longum subsp. Longum aFMT-103 strain, which is classified and named as Bifidobacterium longum subsp. Longum, is preserved in Guangdong Microbial Culture Collection Center, and has a preservation number of GDMCC No: 65181. The invention also provides a preparation method of the bifidobacterium longum subsp. Longum aFMT-103 strain. The invention further provides a microbial preparation containing the aFMT-103 bacterial strain. In addition, the invention also provides an application of the strain or the microbial preparation in preparation of an anti-depression product, and also provides an anti-depression product. The bifidobacterium longum subsp. Longum aFMT-103 strain has the advantages that the bifidobacterium longum subsp. Longum aFMT-103 strain is separated from the faeces of healthy adults; the strain has a remarkable anti-depression effect, can be used for preparing a preparation for resisting depression symptoms, and is of great significance in prevention and adjuvant therapy of depression.

The invention belongs to the technical field of microorganisms, and particularly relates to application of bifidobacterium longum in preparation of products for prevention, treatment and / or adjuvant treatment of pneumonia. The preservation number of the bifidobacterium longum is GDMCC No: 65969, and the bifidobacterium longum can improve the body weight decrease trend of a pneumonia mouse and reduce the lung visceral organ index of LPS increase; the content of pro-inflammatory factors such as IL-1beta, TNF-alpha and IL-6 in serum is remarkably reduced, mRNA expression of inflammation-related genes such as COX-2, IFN-gamma and TNF-alpha in lung tissue is reduced, and dose dependence is achieved; meanwhile, alveolar structure damage and inflammatory cell infiltration of mouse lung tissue are relieved, and lung tissue pathological damage is repaired. The strain can be used as a core component for developing pneumonia prevention or adjuvant therapy related products, provides a novel microbial intervention means for pneumonia prevention and treatment, and has important application value.

The invention belongs to the field of nano-medicine and traditional Chinese medicine, and particularly discloses an antioxidant nano-material based on self-assembly of traditional Chinese medicine and copper ions and a preparation method thereof.The nano-material is prepared from BPCu nano-particles formed by self-assembly of berberine and procyanidine B2 under induction of the copper ions, the BPCu nano-particles are further subjected to surface modification through polyvinylpyrrolidone, and the antioxidant nano-material is prepared. And the stably dispersed PVP-coated BPCu nano structure is obtained. The material is small in particle size, uniform in distribution, good in water solubility and storage stability, excellent in free radical scavenging capacity and catalase-like activity and suitable for adjuvant therapy of oxidative stress related diseases, and the preparation method is easy and convenient to operate, does not need an organic solvent and has good industrialization and disease treatment potential.

The embodiment of the invention provides a hemodialysis fatigue patient-oriented health monitoring and propaganda treatment system, which comprises a cloud server and a first communication device, the patient holds the first communication device, and the cloud server comprises a health data collection module used for obtaining subjective health data and objective health data of the patient; the objective health recognition module is used for determining a first health state of the patient according to the objective health data; the subjective health recognition module is used for recognizing emotion information of the patient according to the objective health data; the reminding propaganda and education module is used for determining a pushing time point according to the living habits of the patient, the first health state and a preset treatment scheme, and pushing treatment reminding and health propaganda and education data to the first communication equipment at the pushing time point in combination with the emotion information of the patient; according to the system provided by the invention, an omnibearing and intelligent health management and adjuvant therapy platform is provided, help can be provided for the patient physiologically and psychologically at the same time, and the compliance of the patient to treatment is improved.

The utility model belongs to the technical field of medical equipment, and provides a medical bed for adjuvant therapy, which comprises a base, a bed board component and a lifting mechanism, and the lifting mechanism is used for connecting the base with the bed board component and driving the bed board component to lift; the lifting mechanism comprises at least three lifting pieces which are distributed in an axial symmetry mode with the gravity center of the medical bed as the center. The bed board assembly comprises a bed board supporting frame, the bed board supporting frame comprises a plurality of pieces of angle aluminum, a frame structure is formed through the multiple pieces of angle aluminum, and at least one piece of angle aluminum is used for providing a horizontal sliding rail. The medical bed is simple in structure, high in structural reliability and light in product weight, manufacturing, transporting and installing processes can be simplified, the transporting space requirement and the installing position bearing requirement for a user are lowered, and the acceptability of the user is improved.

The invention discloses an antibacterial dressing based on gallic acid-copper coated gamma-polyglutamic acid and a preparation method and application thereof, and belongs to the technical field of biomedicines.The preparation method comprises the steps that gallic acid and copper chloride dihydrate are dissolved in pure water according to the mass ratio of 3: 1, and stirring is conducted to form a solution I; stirring and reacting the solution I at 40 DEG C for 24 hours, centrifuging, collecting precipitate, washing with pure water, and freeze-drying to obtain gallic acid-copper nanoparticles; the gallic acid-copper nanoparticles and gamma-polyglutamic acid powder are mixed and dissolved in pure water according to the mass ratio of 3: 20, and after freeze drying, gallic acid-copper coated gamma-polyglutamic acid hydrogel powder is obtained. The gallic acid-copper coated gamma-polyglutamic acid hydrogel powder disclosed by the invention can absorb exudate near a wound and is subjected to in-situ gelation to form a hydration layer, so that damage to newborn tissues caused by frequent dressing replacement is avoided; it is verified that the healing promoting effect of the hydrogel can be remarkably enhanced through blue light adjuvant therapy, and the healing speed of infected wounds is remarkably increased.

The invention discloses lactobacillus crispatus capable of efficiently inhibiting alpha-glucosidase and application of the lactobacillus crispatus. The lactobacillus crispatus JQH7 strain provided by the invention is separated and identified from human excrement, has relatively strong self-aggregation capability which can reach about 96% in 24 hours, can be better adhered to biological or non-biological surfaces, and is beneficial to effective colonization in an intestinal environment. Meanwhile, the JQH7 strain has certain antioxidant capacity, and the scavenging rate of a bacterial suspension of the JQH7 strain on DPPH free radicals is 49.18%; the JQH7 strain has the capability of efficiently inhibiting alpha-glucosidase, the effect of the JQH7 strain is equivalent to that of a clinical medicine acarbose, and compared with the acarbose, the JQH7 strain is safe in source, free of side effects, low in price, easy to obtain and easy to prepare. The invention provides more sources and choices for preparing preparations for efficiently inhibiting alpha-glucosidase and hypoglycemic products, provides a new thought for adjuvant therapy of diabetes, and is beneficial to improving and controlling the blood sugar of diabetics.

The utility model discloses a bone fixing splint device, and particularly belongs to the technical field of bone tumor adjuvant therapy, the bone fixing splint device comprises a main fixing plate attached to the outer side of a knee, an auxiliary fixing plate attached to the inner side of the knee and a connecting bandage, and the connecting bandage is sequentially fixed with the main fixing plate and the auxiliary fixing plate. The bone fixing splint device further comprises a fixing splint assembly attached to the front side and the rear side of the knee, the fixing splint assembly comprises a bottom plate, an extension plate and a locking piece used for positioning the extension plate, a sliding groove matched with the extension plate to slide in a telescopic mode is formed in the middle of the bottom plate, and the bottom plate is fixed to the connecting bandage. The bone fixation splint device can adjust the lengths of the front and rear splints of the knee under the condition of fixing the two sides of the knee, so that the aim of not influencing the knee joint movement of a patient is fulfilled.

The invention belongs to the technical field of microorganisms, and particularly relates to application of bifidobacterium longum in improving immunity and preparing products for preventing, treating and / or assisting in treating rhinitis. The preservation number of the bifidobacterium longum is GDMCC No: 65969, and the bifidobacterium longum can reduce the levels of MDA and NO in serum of mice and improve the activity of SOD and CAT and the content of GSH so as to relieve oxidative stress injury; inflammatory cell infiltration of nasal mucosa is reduced, and lung tissue inflammatory mediator level and inflammation-related gene expression are reduced to inhibit inflammation; th1 / Th2 immune balance is regulated, Th2 type cytokines are reduced, Th1 type cytokines are increased, and the high-dosage effect is close to that of loratadine. The strain has a treatment effect on allergic rhinitis through multiple mechanisms, and a new choice is provided for treatment of the strain.

The invention belongs to the technical field of biological medicines, and particularly relates to application of a BACE2 inhibitor and a composition in preparation of a medicine for treating arteriovenous fistula stenosis after renal failure. The invention provides an application of a BACE2 inhibitor and a composition thereof in preparation of drugs for prevention, adjuvant therapy or treatment of arteriovenous fistula stenosis after renal failure. According to the medicine, by reducing the expression level of BACE2 and reducing the content of soluble sVEGFR3, construction of a lymphatic network on the surface of arteriovenous fistula after renal failure is promoted, inflammation infiltration is relieved or neointima production is relieved, and the effects of prevention, adjuvant therapy or treatment of arteriovenous fistula stenosis after renal failure are achieved. The BACE2 inhibitor composition provided by the invention is simple in preparation method, can play a role in slow release of the BACE2 inhibitor, and is an effective intervention means for preventing and treating arteriovenous fistula stenosis after renal failure.

Disclosed are multi-peptide compositions and / or methods of use of the multi-peptide compositions for patients with resected (or definitively treated) high-risk uveal melanoma. Pharmaceutically acceptable embodiments administered to patients may raise an immune system response against uveal melanoma cells, leading to a decrease in uveal melanoma cell number. Further embodiments may take the form of an adjuvant therapy or a neoadjuvant therapy, as monotherapy or in combination with other therapies.

The invention provides a baking lamp for surgical nursing, and relates to the technical field of nursing instruments. The baking lamp for surgical nursing comprises a base, a connecting column is arranged at the position, close to the rear side edge, of the center of the upper end face of the base, the upper end of the connecting column is movably connected with a first supporting rod through a first connecting piece, and the upper end of the first supporting rod is movably connected with an adjusting structure through a second connecting piece; the other end of the adjusting structure is connected with a lighting structure, the lighting structure comprises a lampshade, a bulb is arranged in the lampshade, a storage groove is formed in the center of the lower end face of the lampshade, a folding sleeve is fixedly connected to the interior of the storage groove, and a protective ring is fixedly connected to the lower end of the folding sleeve. By arranging the lighting structure, when a light source is scattered and the whole support is inconvenient to adjust during use, the folding sleeve connected with the protective ring is pulled out downwards to form a fence, scattering of the light source is reduced, pertinence is higher, and adjuvant therapy is better facilitated.

The invention discloses a bacterial strain with an anti-tumor effect and application of the bacterial strain, the bacterial strain is Lactobacillus paracasei Biohalo 27, the bacterial strain is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC NO.34917; the preservation time is June 16, 2025; the screened strain with the anti-tumor effect has the effects of inhibiting proliferation and migration of rectal cancer cells and breast cancer cells, retarding the cell cycle and promoting cell apoptosis, so that the anti-tumor purpose is achieved, and the strain can be used as a potential application value of probiotic adjuvant therapy.

The invention relates to application of lactobacillus helveticus HH-LPH17 in preparation of medicine for assisting in relieving inflammatory bowel diseases and relates to the technical field of probiotic compositions.The probiotic composition for treating the inflammatory bowel diseases comprises, by weight, 10 parts to 80 parts of lactobacillus johnsonii LBJ 456, 10 parts to 60 parts of lactobacillus helveticus HH-LPH17, 10 parts to 60 parts of lactobacillus acidophilus HH-LA26 and 10 parts to 60 parts of bifidobacterium longum HH-BL18. The composition comprises the following components in parts by weight: 10-60 parts of bifidobacterium bifidum HH-BB27 and 10-60 parts of bifidobacterium longum subspecies infantis HH-BI27. According to the probiotic composition for treating the inflammatory bowel disease, probiotic strains with specific effects are screened out, the combination proportion of the probiotic strains is optimized, the probiotic composition for treating the inflammatory bowel disease is prepared, and a novel safe and effective adjuvant therapy method is provided for treatment of the inflammatory bowel disease.

The invention relates to a probiotic composition for treating rheumatoid arthritis and application thereof, and relates to the technical field of probiotic compositions.The probiotic composition for treating rheumatoid arthritis is prepared from, by weight, 10-40 parts of lactobacillus johnsonii LBJ 456, 10-30 parts of lactobacillus helveticus HH-LPH17 and 10-30 parts of lactobacillus acidophilus HH-LA26. The bifidobacterium longum subsp. Longum HH-BL18, the bifidobacterium bifidum HH-BB27 and the bifidobacterium longum subsp. Infantis HH-BI27 are prepared from the following raw materials in parts by weight: 10 to 40 parts of bifidobacterium longum subsp. Probiotic strains with specific effects are screened out, the combination proportion of the probiotic strains is optimized, the probiotic composition for treating rheumatoid arthritis is prepared, and a novel safe and effective adjuvant therapy method is provided for treatment of RA.

The invention relates to a class of small molecule inhibitors of GPR68 / OGR1, a proton-sensing / stretch-sensing / sheer-stress-sending G-protein coupled receptor, and related receptors GPR4 and GPR65. These inhibitors are useful as a therapeutic for glioblastoma and other neoplasms, as a monotherapy or adjuvant, and also can be used as a treatment for other conditions, such as osteoporosis, inflammatory bowel disease, autoimmune and chronic inflammatory diseases such as multiple sclerosis and inflammatory pain syndromes, GERD, aspiration pneumonitis, bacterial and viral pneumonia, COPD, acute respiratory distress syndrome (ARDS), and COVID-19.

The invention belongs to the technical field of microorganisms, and particularly discloses lactobacillus paracasei and application thereof, the lactobacillus paracasei is named as lactobacillus paracasei Jlus66, the lactobacillus paracasei is preserved in China General Microbiological Culture Collection Center on March 31, 2021, the preservation address is No.3, No.1 Yard, Beichen West Road, Chaoyang District, Beijing, and the preservation number is CGMCC No.22101. The lactobacillus paracasei is named as lactobacillus paracasei Jlus66. The lactobacillus paracasei Jlus66 has the obvious beneficial effects in the treatment of the alopecia areata, and the obvious beneficial effects comprise the immune regulation, the anti-oxidation and anti-inflammatory effects and the optimization of the intestinal tract-skin axis. In addition, the medicine is high in safety and small in side effect, so that the medicine becomes a promising adjuvant therapy means.

The invention relates to a dynamic intelligent fixing device for lower limb rehabilitation, which belongs to the technical field of medical instruments and comprises a dynamically adjustable leg supporting structure, a self-adaptive foot fixing device, a multi-modal stimulation system, a double-shaft linkage movement mechanism and an intelligent regulation and control system. The dynamic adjusting structure and the self-adaptive fixing device can adapt to different leg circumferences, foot types and joint motion ranges, and comfortable fixing and standard movement of a patient are guaranteed; the multi-mode stimulation system is combined with mechanical movement, pneumatic massage and myoelectricity stimulation to synergistically promote blood circulation of the lower limbs; the intelligent regulation and control system collects multi-dimensional physiological data in real time and dynamically optimizes motion parameters and stimulation intensity. The device solves the problems that an existing device is poor in adaptability, single in stimulation, lagged in regulation and control and the like, individualized precise adjuvant therapy is achieved, the lower limb rehabilitation effect and clinical benefits of postoperative lower limb fixation and VTE prevention are effectively improved, and meanwhile the operation complexity of medical staff is reduced.

The invention relates to the technical field of medical instruments, in particular to a constipation adjuvant therapy appliance and a using method thereof.The constipation adjuvant therapy appliance comprises an insertion tube, a vibration sleeve is arranged at the inner end of the insertion tube, and a vibration motor is arranged in the vibration sleeve; the outer end of the insertion pipe is connected with a medium pipeline used for inputting or outputting a medium into or out of a pipe cavity of the insertion pipe. A plurality of protruding blocks are arranged on the pipe wall of the outer side of the insertion pipe. Through mechanical pressure generated by expansion of the insertion tube and the adjusting cavity of the insertion tube and local stimulation of the outer side protruding block on the rectum wall, low-frequency vibration of the vibration motor in the vibration sleeve is combined, a rectum wall mechanical receptor and a nerve conduction path are cooperatively activated in a multi-mode mode, defecation reflex is triggered, and therefore targeted intervention on defecation reflex disorder of a constipation patient is achieved. The defect that a traditional therapy does not touch a neural mechanism is overcome, and a comprehensive solution from physiological reflex activation to mechanical power enhancement is provided for constipation treatment.