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183 results about "Naringin" patented technology

Naringin is a flavanone-7-O-glycoside between the flavanone naringenin and the disaccharide neohesperidose. The flavonoid naringin occurs naturally in citrus fruits, especially in grapefruit, where naringin is responsible for the fruit's bitter taste. In commercial grapefruit juice production, the enzyme naringinase can be used to remove the bitterness created by naringin. In humans naringin is metabolized to the aglycone naringenin (not bitter) by naringinase present in the gut.

Application of narirutin in improving intestinal flora homeostasis of food allergy organism

The invention belongs to the technical field of food functional ingredient nutriology research, and discloses application of narirutin in improving the intestinal flora homeostasis of food allergy organisms. The narirutin can adjust the relative abundance value of certain intestinal flora by adjusting the diversity of the intestinal flora of a food allergy body, improve the relative abundance of beneficial bacteria and harmful bacteria, and can influence the metabolism of short-chain fatty acid of the intestinal flora of the food allergy body, so that the food allergy body is improved. Further, the application of the narirutin in improving the intestinal flora homeostasis of food allergy organisms is realized. The application of narirutin in the research fields of nutriology, biology and pharmacology is expanded.
Owner:JILIN UNIVERSITY

A preparation method and application of Huajuhong and Huajuhongtai for relieving cough, reducing phlegm, protecting lungs, enhancing efficacy and removing bitterness

The present invention belongs to the technical field of traditional Chinese medicine, and specifically relates to a preparation method and application of Huajuhong and Huajuhong embryo for relieving cough, reducing phlegm, protecting lungs, enhancing efficacy and removing bitterness. The preparation method of the present invention is: take the raw materials (Huajuhong, Huajuhong embryo) and mix them with sodium bicarbonate aqueous solution or sodium carbonate aqueous solution, warm them at 50-90°C, and then dry them to obtain the prepared products. Experimental results show that the preparation method of Huajuhong and Huajuhong embryo of the present invention significantly changes the content of their ingredients, and the efficacy of the prepared prepared products is significantly improved, including a significant increase in the efficacy and activity of relieving cough, reducing phlegm and protecting lungs; moreover, the content of the main bitter substance naringin is significantly reduced after preparation, and the bitterness in the raw materials can be effectively removed, which is very beneficial for oral drinking by patients with cough, phlegm and lung damage.
Owner:GUANGZHOU UNIVERSITY OF CHINESE MEDICINE

Traditional Chinese medicine skin cream for repairing skin and preparation method thereof

The invention relates to the technical field of skin care product preparation, in particular to traditional Chinese medicine skin care cream for repairing skin and a preparation method thereof. The preparation method comprises the following steps: preparing acylated alkyl glucoside; preparing a turpinia arguta extract; preparing a suspension of the naringin and the turpinia arguta extract; and preparing the traditional Chinese medicine skin cream for repairing the skin. According to the method, myristic acid and alkyl glycoside are used for preparing acylated alkyl glycoside, myristic acid and alkyl glycoside are subjected to acylation reaction through lipase Lipozyme435 enzyme, damage to a flavone structure in the microwave extraction process is avoided, after alkyl glycoside acylation, the lipophilicity is remarkably enhanced, and the lipophilicity of alkyl glycoside is remarkably reduced. Due to the enhanced lipophilicity, the alkyl glycoside can more effectively interact with fat-soluble flavonoid compounds, so that the solubility and dispersity of the alkyl glycoside in a fat phase are improved, the oxidation loss of flavonoid substances in the extraction process of the turpinia arguta leaves is reduced, and the content of the flavonoid substances in the turpinia arguta leaf extract is increased.
Owner:JIANGXI ACAD OF FORESTRY

Preparation method of high-content narirutin and hesperidin extract

The invention provides a preparation method of a high-content narirutin and hesperidin extract, which is characterized in that a microwave-assisted eutectic solvent optimization process is utilized to prepare narirutin and hesperidin in pericarpium citri reticulatae, and the extraction conditions of a microwave-assisted eutectic solvent are optimized through a single factor experiment and a BBD response surface experiment. The optimal extraction conditions are as follows: the molar ratio of choline chloride to ethylene glycol is 1: 6, the water content is 10%, the solid-liquid ratio is 10mg / mL, the microwave extraction temperature is 94 DEG C, the time is 41 minutes, and the power is 400W. According to the method, the eutectic solvent is adopted as the extraction solvent, and the microwave-assisted extraction technology which has relatively high energy transmission efficiency and is easy to apply on a large scale is combined, so that the efficiency is expected to be improved in industrial application in the future, the extraction process is more environment-friendly and sustainable, and a new thought is provided for deep processing and utilization of rutaceous plant resources.
Owner:JILIN UNIVERSITY

Composition and application thereof

The invention discloses a composition and application thereof, and the composition comprises synephrine or a pharmaceutically acceptable salt thereof, and further comprises naringin, neohesperidin and / or hesperidin. The composition prepared by compounding the synephrine or the pharmaceutically acceptable salt thereof with the naringin, the neohesperidin and / or the hesperidin has the effects of relieving, repairing, resisting wrinkles, easing pain, relieving itching or resisting allergy when being used as a functional component of a skin care product; when being used as a functional component of a scalp care product, the shampoo has the effects of removing dandruff, removing oil, relieving itching or preventing alopecia.
Owner:SHANGHAI JAKA BIOTECH CO LTD

Preparation method and application of high-activity multi-level pore boric acid imprinting hydrogel microsphere adsorbent

The application discloses a preparation method of a high-activity multi-level-pore boronic acid imprinting hydrogel microsphere adsorbent and application of the adsorbent to selective adsorption of a flavonoid compound naringin (NRG). The application enhances surface functionalization of COFs by dopamine modification, prepares thiol functionalized covalent organic framework microspheres, synthesizes thiol microspheres by using an emulsion interfacial polymerization method, prepares COFs boron affinity imprinting microsphere adsorbents based on boron affinity, and applies the adsorbents to selective adsorption of NRG in agricultural wastewater. The prepared adsorbent has a significant multi-layer adsorption effect, and the adsorption capacity is significantly improved by using boron affinity. The multi-level-pore structure of the COFs microspheres provides abundant sites for adsorption, and significantly improves the mass transfer rate. In addition, the prepared adsorbent has significant specificity in adsorption and separation of NRG, and provides a promising adsorption material for industrialized separation of NRG.
Owner:JIANGSU UNIV +1

Application of CsCOMT2 gene in breeding of new citrus varieties

ActiveCN120905289BBiotechnologyNaringin
The application discloses application of a CsCOMT2 gene in breeding of new citrus varieties, belongs to the technical field of genetic engineering, and particularly relates to application of the CsCOMT2 gene in breeding of new citrus varieties, wherein the CDS sequence of the CsCOMT2 gene is shown as SEQ ID NO. 1. The application promotes the content of vitamin P-2, naringin, hesperidin and / or jaceosid in citrus peels by overexpressing the CsCOMT2 gene, and indicates that the CsCOMT2 gene can be used as a candidate gene for breeding of new citrus varieties with high content of vitamin P-2, naringin, hesperidin and / or jaceosid, and a functional new citrus variety is bred by using a genetic engineering method.
Owner:GERMPLASM INNOVATION GRAND SCIENCE CENTER OF WESTERN CHINA (CHONGQING) SCIENCE CITY +1

A method for simultaneously determining multiple index components in Wendan Tablets

The present invention provides a method for simultaneously determining multiple index components in Wendan Tablets. In this method, Wendan Tablets are used as test samples for high-performance liquid chromatography detection to simultaneously determine p-hydroxycinnamic acid, naringin, hesperidin, and glycyrrhizic acid in Wendan Tablets. The method of the present invention can also quantitatively determine the contents of the above four components in Wendan Tablets, and the quantitative determination methods include the external standard method and the multiple components by single marker method. The determination method of the present invention realizes the qualitative and quantitative determination of multiple components (p-hydroxycinnamic acid, naringin, hesperidin, and glycyrrhizic acid) in Wendan Tablets. Among them, the multiple components by single marker quantitative detection method not only ensures the quality, stability, and controllability of the preparation, but also reduces the detection cost of purchasing reference substances, achieving excellent technical effects and having broad application prospects.
Owner:ZHANGZHOU PIEN TZE HUANG PHARM

Bionic bone scaffold composite material prepared through combination of electrostatic spinning and 3D printing and preparation method of bionic bone scaffold composite material

The invention discloses a bionic bone scaffold composite material prepared through combination of electrostatic spinning and 3D printing and a preparation method of the bionic bone scaffold composite material, and relates to the technical field of bionic bone scaffold composite materials. A bionic bone scaffold composite material prepared by combination of electrostatic spinning and 3D printing is characterized by comprising 80 to 100 parts of a biodegradable high-molecular polymer, 5 to 30 parts of a bioactive inorganic ceramic material, 200 to 500 parts of a solvent, 0.01 to 5 parts of a bioactive factor, 0.1 to 0.5 part of a bacteriostatic active compound and 0.01 to 5 parts of naringin. According to the invention, the metronidazole derivative is used for providing antibacterial ability, and is matched with naringin to realize anti-inflammatory and osteogenesis-promoting synergistic effect, so that the problem of drug resistance or non-uniform drug release of the traditional antibacterial means is avoided, the induction effect of the stent on bone regeneration is enhanced, and the infection risk in the repair process is reduced.
Owner:SHANGHAI YUANDA NEW MATERIAL TECH CO LTD

A method for evaluating the debittering effect of citrus juice resin adsorption

The present invention belongs to the field of food testing technology and provides a method for evaluating the debittering effect of citrus juice by resin adsorption. The method comprises the following steps: adding a sucrose ester emulsifier solution to a naringin solution, measuring the initial and final interfacial tension values, and obtaining the interfacial tension difference; adding the sucrose ester emulsifier solution during the citrus juice preparation process, and then debittering the citrus juice by resin adsorption to obtain the debittered citrus juice; and using the interfacial tension difference of the naringin solution containing the sucrose ester emulsifier as an indicator to determine the debittering effect of the citrus juice by resin adsorption. The present invention evaluates the debittering effect of citrus juice by resin adsorption by measuring the interfacial tension difference of the naringin solution containing the sucrose ester emulsifier. This evaluation method has the advantages of strong anti-interference ability, avoids interference from components such as pectin and pigments, excellent data reproducibility, and low reagent consumption.
Owner:JIANGXI AGRICULTURAL UNIVERSITY +1

Processing technology of rhizoma drynariae

The invention discloses a processing technology of rhizoma drynariae, and belongs to the technical field of processing. The processing technology comprises the following steps: step 1, removing leaves and silt from fresh rhizoma drynariae, washing, slicing, and drying in the sun; step 2, processing the highland barley wine: taking the dried slices, adding the highland barley wine, uniformly stirring, thoroughly covering, frying with slow fire, and cooling to obtain the highland barley wine prepared decoction pieces; and step 3, adding the highland barley rice water into the wine-prepared highland barley decoction pieces, uniformly stirring, thoroughly covering, frying with the highland barley rice hull bran, and frying until the highland barley rice hull bran is dry to obtain the wine-prepared highland barley decoction pieces. According to the preparation method, the traditional processing method of sand blanching and salting is abandoned, the highland barley wine is firstly adopted for processing, then the highland barley rice water is adopted for moistening and the highland barley rice husk bran is adopted for frying, the effect of highland barley in broken bone supplementing processing is fully utilized, the spleen tonifying effect can be further enhanced by means of the highland barley rice, and the spleen tonifying and stomach invigorating effects of the decoction piece are improved. Meanwhile, the content of naringin in the decoction pieces can be remarkably increased through the processes of processing with highland barley wine, moistening with water and frying with bran of highland barley husks.
Owner:SHIJIAZHUANG ZANGNUO BIOTECH

Immature bitter orange extracellular vesicle-like particle as well as preparation method and application thereof

The invention belongs to the technical field of traditional Chinese medicines, and discloses an immature bitter orange-derived extracellular vesicle-like nanoparticle, which is characterized in that the immature bitter orange-derived extracellular vesicle-like nanoparticle is prepared by the steps of crushing immature bitter orange, filtering, centrifuging and resuspending, the average particle size is 60-120 nm, and the particle size of the immature bitter orange-derived extracellular vesicle-like nanoparticle is 20-30 nm. The extracellular vesicle-like nanoparticles are used for entrapment of at least one of naringin, neohesperidin, naringenin and hesperidin. The extracellular vesicle-like nanoparticles derived from immature bitter oranges are simple in preparation method, have liver targeting and good stability, and can be used for preparing medicines for preventing and / or treating liver injury, depression and breast cancer.
Owner:GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Composition for inhibiting bacteria, resisting inflammation, relieving inflammation and repairing sensitive skin

The invention discloses a composition for inhibiting bacteria, resisting inflammation, relieving inflammation and repairing sensitive skin. The composition comprises the following components in parts by weight: 1-5 parts of a sophora flavescens extract; 2-15 parts of a radix scutellariae extract; 5-10 parts of a white peony root extract; 0.2 to 5 parts of a grapefruit extract; and 1-5 parts of pomegranate extract. The composition prepared from the radix sophorae flavescentis extract, the radix scutellariae extract, the radix paeoniae alba extract, the grapefruit extract and the pomegranate extract takes sophocarpidine, baicalin, paeoniflorin, naringin and punicalagin as main functional components to play a synergistic effect, so that the composition has very remarkable effects of inhibiting bacteria, resisting inflammation, relieving inflammation and repairing sensitive skin.
Owner:RENHE GLOBAL (SHANGHAI) GRAND HEALTH RESEARCH INSTITUTE CO LTD

Quality control method for stir-fried rhizoma atractylodis macrocephalae with fructus aurantii

PendingCN120369876AComponent separationNaringinAtractylenolide II
The invention belongs to the technical field of quality detection of traditional Chinese medicines, and discloses a quality detection method of rhizoma atractylodis macrocephalae fried with fructus aurantii, which is characterized by comprising the following steps: performing qualitative analysis on rhizoma atractylodis macrocephalae fried with fructus aurantii by respectively adopting a thin-layer chromatography and an HPLC (High Performance Liquid Chromatography) characteristic chromatogram; a high performance liquid phase external standard curve method is adopted to carry out quantitative analysis on atractylenolide I, atractylenolide II, atractylenolide III, naringin and neohesperidin in the fructus aurantii fried bighead atractylodes rhizome. The invention establishes a thin-layer identification method for rhizoma atractylodis macrocephalae and fructus aurantii in a fructus aurantii fried rhizoma atractylodis macrocephalae processed product; according to the method for establishing the fingerprint spectrum, the similarity of 10 batches of rhizoma atractylodis macrocephalae fried with fructus aurantii ranges from 0.991 to 1.000; the method for determining the content of atractylenolide I, atractylenolide II, atractylenolide III, naringin and neohesperidin is established, scientific support is provided for formulating the quality standard of the characteristic processing decoction pieces of the temporary prescription, and effective guarantee is provided for clinical application of the decoction pieces.
Owner:CHANGZHOU FOOD DRUG & FIBER QUALITY SUPERVISION & INSPECTION CENT (CHANGZHOU GRAIN & OIL QUALITY SUPERVISION & INSPECTION STATION CHANGZHOU FIBER INSPECTION INST)

Sweetener composition and taste-improving agent

PendingUS20260182611A1NaringinNaringenin
The present invention provides a sweetener composition with improved taste quality of a sweet substance. The present invention relates to a sweetener composition containing the following components (A), (B), and (C): (A) at least one γ-glutamyl peptide selected from the group consisting of a compound represented by the formula (I): γ-Glu-X-Gly (I) wherein X is an amino acid residue or an amino acid derivative residue, and a compound represented by the formula (II): γ-Glu-Y (II) wherein Y is an amino acid residue or an amino acid derivative residue, or a salt thereof, (B) at least one compound selected from the group consisting of naringenin, hesperetin, and pinocembrin, or a salt thereof, and (C) a sweet substance.
Owner:AJINOMOTO CO INC

Citrus double-factor anti-allergy plant extract as well as preparation method and application thereof

The invention discloses a citrus two-factor anti-allergy plant extract and a preparation method and application thereof. The citrus two-factor anti-allergy plant extract comprises poncirin and naringin in a mass ratio of (20-25): (6-10). The preparation method of the citrus double-factor anti-allergy plant extract comprises the following steps: carrying out heating reflux on crushed citrus fruits in a 50-80% ethanol solution for 5-8 hours to obtain an extracted crude product; slowly adding an extracted crude product to the column, and controlling the flow rate to be 1-2BV / h; and then eluting with 3-5BV distilled water to remove water-soluble impurities. And eluting with a 30-40% ethanol solution of 2-3BV, collecting the eluent, concentrating, and recrystallizing to obtain the naringin. And eluting with a 50-70% ethanol solution of 2-3BV, collecting the eluent, concentrating, and recrystallizing to obtain poncirin. When the plant extract is used in cosmetics, the cosmetics can have good moisturizing, soothing and other effects.
Owner:JIANGSU BIOEDEN BIOTECHNOLIGY CO LTD

Preparation method and quality detection method of classic famous prescription immature bitter orange and Chinese herbaceous peony powder

The invention provides a preparation method of fructus aurantii immaturus and paeonia lactiflora powder of a classic famous formula The invention also provides a method for detecting the quality of the fructus aurantii immaturus and paeonia lactiflora powder prepared by the preparation method of the classic famous prescription fructus aurantii immaturus and paeonia lactiflora powder. The invention establishes a preparation process of the immature bitter orange and Chinese herbaceous peony powder preparation, and particularly, a process route and key process parameters obtained through systematic research on immature bitter orange charcoal frying process parameters in the formula not only accord with description of the medicine in ancient books, but also can meet actual equipment conditions of modern large-scale production. Within the determined key process parameter range, the decrease amplitude of three heat-sensitive components, namely catechin, narirutin and naringin, which are easy to decompose after being heated in the immature bitter orange charcoal can be controlled within 10%, so that the effectiveness and the quality controllability of the product are ensured. The UPLC method established by the invention can more quickly realize simultaneous detection of eight components in the immature bitter orange and Chinese herbaceous peony powder, can be used as an evaluation method for the process research, and can also be used for controlling the product quality in the production of the immature bitter orange and Chinese herbaceous peony powder.
Owner:SICHUAN NEO GREEN PHARMA TECH DEV

Construction method of fingerprint spectrum of Shenxiong Tongmai capsule

The invention relates to a construction method of a fingerprint spectrum of Shenxiong Tongmai capsule, which comprises the following steps: dissolving a ferulic acid standard substance, a hesperidin standard substance, a ginsenoside Re standard substance, a neohesperidin standard substance and a naringin standard substance in methanol to prepare a mixed reference substance solution; the method comprises the following steps: respectively dissolving contents of Shenxiong Tongmai capsules in a plurality of batches in a methanol aqueous solution to prepare a plurality of test solutions; respectively carrying out high performance liquid chromatography detection on the mixed reference substance solution and the plurality of test sample solutions to obtain a high performance liquid chromatogram of the mixed reference substance solution and high performance liquid chromatograms of the plurality of test sample solutions; determining characteristic peaks and identifying chemical components of the characteristic peaks, and calculating relative retention time of other characteristic peaks by taking the characteristic peak corresponding to hesperidin as a reference peak to obtain the fingerprint spectrum. The fingerprint spectrum obtained by the construction method disclosed by the invention can well reflect information of a plurality of index components of the Shenxiong Tongmai capsule.
Owner:NAT ENG RES CENT FOR TRADITIONAL CHINESE MEDICINE

A highly active epiglottis-removing decoction and its application in the preparation of antitussive drug compositions

PendingCN122075510Aachieve enrichmentSignificant antitussive activityOrganic active ingredientsGranular deliveryNaringinAntitussive drugs
This invention relates to a highly active effective fraction of the Epiglottis-Clearing Decoction and its application in the preparation of antitussive drug compositions, belonging to the field of traditional Chinese medicine extract technology. The effective fraction contains hydroxysaffron yellow A, paeoniflorin, naringin, and neohesperidin, with the total content of these four components not less than 20% of the total mass of the effective fraction. The effective fraction of this invention is prepared by purification with macroporous resin. Compared with the freeze-dried powder of the traditional Epiglottis-Clearing Decoction, the total content of the four active ingredients is increased from 3.32% to 20.87%, achieving a more than 6-fold high-efficiency enrichment. Animal pharmacodynamic experiments show that the antitussive effect of a low dose (275.5 mg / kg) of this effective fraction is comparable to that of the freeze-dried powder of the original decoction (1928 mg / kg), reducing the dosage to about 1 / 7 of the original formula, demonstrating a significant "synergistic effect with reduced dosage" technical effect. The effective active ingredients provided by this invention have a clear content and stable quality, and can be made into modern preparations such as tablets, capsules or granules, solving the problems of large volume, inaccurate dosage and poor patient compliance of traditional decoctions.
Owner:BINZHOU MEDICAL COLLEGE +1

Oral composition and method for ameliorating harsh taste

An object of this invention is to suppress the harsh taste particular to an extract of a plant of the genus Salacia. An oral composition comprises an extract of a plant of the genus Salacia and naringin, the naringin being present in an amount of 0.001 to 6 parts by weight per part by weight of the extract of a plant of the genus Salacia, on a dry weight basis. A method for ameliorating the harsh taste of an extract of a plant of the genus Salacia comprises combining 0.001 to 6 parts by weight of naringin with 1 part by weight of the extract of a plant of the genus Salacia, on a dry weight basis.
Owner:KOBAYASHI PHARMA CO LTD

Heart-protecting granule identification and quality control method based on thin layer chromatography

The invention discloses a heart-protecting granule identification and quality control method based on thin layer chromatography, and belongs to the technical field of medicine detection. The thin-layer chromatography identification method comprises the following steps: identifying astragalus membranaceus by taking astragaloside as a reference substance, identifying wine-treated rhubarb by taking chrysophanol and emodin as reference substances, identifying leech by taking a leech medicinal material as a reference substance, identifying liquorice by taking liquiritin and a liquorice medicinal material as reference substances, and identifying radix rehmanniae by taking catalpol as a reference substance. And identifying salvia miltiorrhiza by taking salvianolic acid B and salvia miltiorrhiza medicinal materials as reference substances, and identifying fructus aurantii by taking naringin and neohesperidin as reference substances. By establishing the thin-layer chromatography identification method of the heart-protecting granules, an exclusive developing solvent and a developing mode are adopted, accurate identification is achieved according to the characteristics of spot colors, fluorescence characteristics and the like of corresponding positions of a test substance chromatography, a reference substance and a reference medicinal material chromatography, and the method is easy and convenient to operate, low in detection cost and high in repeatability and specificity; and quality control can be effectively carried out in the production process of the heart-protecting granules.
Owner:ZHUHAI TIANDA RES & DEV CO LTD

Citron extract as well as preparation method and application thereof

PendingCN120078677ACosmetic preparationsToilet preparationsNaringinExtract (substance)
The invention belongs to the technical field of plant extraction, and provides a citron extract as well as a preparation method and application thereof. The preparation method comprises the following steps: pre-treating to remove volatile components by using a water steam distillation method, heating, refluxing and extracting by using ethanol, filtering, concentrating, separating and purifying by using macroporous resin, concentrating, drying and the like. The extraction efficiency is high, energy is saved, the environment is protected, the production period is greatly shortened, and the citron active matter can be rapidly extracted. The prepared citron extract is stable in quality, the content of active ingredients such as naringin and the like in the extract is relatively high, volatile ingredients such as essential oil and the like are removed, and the purity of the extract and the safety of people with sensitive skin are guaranteed. The obtained citron extract has excellent skin moisturizing, anti-inflammatory, anti-allergy, emotion beautifying and anti-aging capabilities, is very friendly to people with sensitive skin, has higher stability, is suitable for large-scale production, and has important application value in preparation of large-scale healthy products and products with emotion beautifying or oral beautifying effects.
Owner:YUNNAN BOTANEE BIO TECH GRP CO LTD +2

HPLC fingerprint spectrum construction method of Tibetan medicine apium graveolens

The invention relates to an HPLC (High Performance Liquid Chromatography) characteristic chromatogram construction method of Tibetan medicine apium graveolens, and belongs to the technical field of detection and analysis. According to the method, a test solution is obtained through a simple and rapid pretreatment method, a high performance liquid chromatograph and a gradient elution mode are adopted, a characteristic spectrum is established, 14 characteristic peaks exist in total, 6 index components of chlorogenic acid, rutin, daidzein, naringin, luteolin and cumin are identified, the relative retention time RSD% of the characteristic peaks is within 3%, and the relative retention time RSD% of the characteristic peaks is within 3%. The wave crest separation of each component is good. According to the method disclosed by the invention, a fingerprint spectrum establishment mode is adopted, so that the medicinal material quality of the apium graveolens can be more effectively ensured, and the blank in the aspect of apium graveolens characteristic spectrum research in the existing standard is filled up.
Owner:SHIJIAZHUANG ZANGNUO BIOTECH +1

A method for constructing a fingerprint spectrum of Tianyang Qianggu Yin based on HPLC and application thereof

PendingCN122651923AHplc fingerprintNaringin
The application provides a HPLC-based method for constructing a fingerprint spectrum of Tianyang Qianggu Yin and application thereof, and belongs to the technical field of traditional Chinese medicine detection.The method provided by the application comprises the steps of preparing a test sample solution, preparing a mixed control sample solution, HPLC determination, fingerprint spectrum construction and content determination.The application first establishes a HPLC fingerprint spectrum suitable for water-soluble extracts of Tianyang Qianggu Yin compound, and simultaneously realizes accurate content determination of six components, i.e., neotamanoxin, naringin, alpinumisine A, alpinumisine B, alpinumisine C and icariin.The application has strong specificity, high precision, good repeatability and excellent accuracy.The application provides scientific and controllable technical support for the production quality consistency and efficacy stability of Tianyang Qianggu Yin, and can be used for quality control and batch consistency evaluation of the compound preparation.
Owner:新疆医科大学第四附属医院

Formula and preparation method of exocarpium citri rubrum probiotic fermented beverage

The invention relates to the technical field of probiotic fermented beverages, in particular to a formula and a preparation method of an exocarpium citri rubrum probiotic fermented beverage, and the exocarpium citri rubrum probiotic fermented beverage comprises the following raw material components: 20-30% of exocarpium citri rubrum peel, 2-3% of probiotic strains, 8-12% of a herbal extract, 0.5-2% of a compound enzyme synergist, 1-2% of soybean peptides, 0.05-0.1% of vitamin C, 0.01-0.03% of natural menthol, 1-5% of natural honey and the balance of purified water. According to the invention, through the enzymolysis extraction of the exocarpium citri rubrum and the fermentation of the exocarpium citri rubrum and the fermentation of the probiotics, active ingredients are retained, the composition proportion is optimized, the content of naringin and the survival rate of total flavonoids and the probiotics are relatively good, bitter substances can be decomposed and small molecule peptides can be released in the enzymolysis process, the bitter and pungent taste of the exocarpium citri rubrum can be effectively removed, the nutritional ingredients of the exocarpium citri rubrum can be ensured, and the nutritional value of the exocarpium citri rubrum can be improved. According to the present invention, the food and medicine homology is achieved, such that the developed citrus reticulata blanco beverage has good competitiveness in taste and multi-dimensional nutrition, the citrus reticulata blanco value is well developed, and the practicality is improved.
Owner:ZHONGXIN TECH (GUANGDONG) CO LTD

Gynecological antibacterial gel and preparation method thereof

The invention belongs to the technical field of medical gel, and particularly relates to gynecological antibacterial gel and a preparation method thereof. The gel comprises an antibacterial phase and a bacterium promoting phase, and broad-spectrum inhibition of common pathogenic bacteria is achieved through the synergistic proportion of naringin, nisin and ethyl lauroyl arginate hydrochloride; meanwhile, a lactobacillus rhamnosus metabolite, sodium hyaluronate and the like are introduced to construct a bacterium promoting phase, and probiotic colonization and vagina micro-ecological balance reconstruction are promoted. The pH value of the gel is stabilized at 4.0-4.5, and the gel has good rheological properties and retention performance. In the preparation method, all the components are added step by step, the system temperature and stirring conditions are controlled, and the component activity and the product stability are guaranteed. The traditional Chinese medicine composition can effectively relieve bacterial vaginitis, fungal infection and micro-ecological disorder, and has a synergistic, safe and mild comprehensive nursing effect.
Owner:CHANGSHA RONGXI BIOTECHNOLOGY CO LTD

Citron extract sleeping mask and preparation method thereof

The invention relates to the technical field of masks, in particular to a citron extract sleeping mask and a preparation method of the citron extract sleeping mask. 15-25 parts of an intelligent moisturizing system; 3-8 parts of a brain wave synergistic sleep-aiding compound; 8-12 parts of a skin barrier repair system; 2-5 parts of a texture conditioning agent; 0.5 to 1.5 parts of an anticorrosion system; 0.1 to 0.5 part of a fragrance system; according to the present invention, the dual targeting delivery system is developed, the fat-soluble d-limonene is wrapped in the liposome, and the water-soluble naringin is delivered through the nano-micelle; the phospholipid bilayer structure of the liposome is similar to the skin cuticle, so that the transdermal absorption of d-limonene can be promoted. The nano-micelle realizes stable embedding and slow release of the water-soluble flavone through a hydrophilic shell and a hydrophobic core of the nano-micelle. By means of the design, the percutaneous absorption efficiency of the active ingredients is improved, and time-sequence-controllable release is achieved.
Owner:SHAANXI SCI TECH UNIV

A method for improving high temperature resistance of citrus by exogenous spraying of naringin

This invention discloses a method for enhancing the high-temperature resistance of citrus through exogenous spraying of naringin, belonging to the field of agricultural technology. The method involves preparing naringin into a formulation and spraying it exogenously onto the leaves of citrus plants. Experiments show that after treatment with naringin, phenotypic damage such as wilting and curling of citrus seedling leaves under high-temperature stress is significantly alleviated; the maximum photochemical efficiency of photosystem II (Fv / Fm) is significantly increased; electrolyte leakage rate and malondialdehyde content are significantly reduced; and the accumulation of hydrogen peroxide and superoxide anions is effectively inhibited. This invention utilizes naturally sourced naringin to significantly enhance the tolerance of citrus to high-temperature stress through multiple mechanisms, including maintaining photosynthetic system function, protecting cell membrane integrity, inhibiting membrane lipid peroxidation, and scavenging reactive oxygen species. Furthermore, the method is simple to operate, environmentally friendly, and low-cost, making it suitable for stress-resistant citrus cultivation.
Owner:HUAZHONG AGRI UNIV