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269 results about "Acetophenone" patented technology

Acetophenone is the organic compound with the formula C₆H₅C(O)CH₃ (also represented by the pseudoelement symbols PhAc or BzMe). It is the simplest aromatic ketone. This colorless, viscous liquid is a precursor to useful resins and fragrances.

Detergents and cleaning compositions with improved Anti-redeposition properties

The present invention relates to detergents and cleaning compositions that comprise a surfactant, an anti-redeposition agent, and an effective amount of 1,2-heptanediol and / or 2,3-heptanediol or a specific type of anti-redeposition boosting agent, such as alkanediols, glyceryl caprylate, 4-hydroxyacetophenone, ethyl hexyl glycerin or tropolone, and the use of said detergents and cleaning compositions for the preparation of a detergent and cleaning product for household, institutional and industrial application. Furthermore, the present invention relates to a method of treating a stained and / or soiled substrate, using the detergents and cleaning compositions according to the present invention. Additionally, the present invention relates to the use of 1,2-heptanediol and / or 2,3-heptanediol or of specific substances as defined herein for boosting the activity of an anti-redeposition agent in a detergent and cleaning composition and / or for improving cleaning performance of a detergent and cleaning composition. Moreover, the present invention relates to a method of boosting the activity of an anti-redeposition agent in a detergent and cleaning composition and / or of improving cleaning performance of a detergent and cleaning composition by adding an effective amount of 1,2-heptanediol and / or 2,3-heptanediol or of specific anti-redeposition agents, such as alkanediols, glyceryl caprylate, 4-hydroxyacetophenone, ethyl hexyl glycerin or tropolone to said detergent and cleaning composition. Finally, the present invention relates to the use of 1,2-heptanediol, 2,3-heptanediol or a mixture comprising 1,2-heptanediol and 2,3-heptanediol or at least one anti-redeposition boosting agent, such as alkanediols, glyceryl caprylate, 4-hydroxyacetophenone, ethyl hexyl glycerin or tropolone as anti-redeposition agent.
Owner:SYMRISE GMBH & CO KG

Preparation method and application of reductive amination catalyst

The invention discloses preparation and application of a reductive amination catalyst. The preparation method of the catalyst comprises the following steps: step 1, preparing an SrTiO3 carrier; step 2, loading a nickel source into the prepared SrTiO3 carrier to form a nickel-loaded SrTiO3 catalyst precursor; and step 3, roasting the SrTiO3 catalyst precursor to obtain the SrTiO3 loaded nickel catalyst. Large-scale production of the non-noble metal catalyst is realized by adopting a co-precipitation method and an impregnation method which are simple in process and environment-friendly under the condition of room temperature, the obtained material can be used for reductive amination reaction of acetophenone under the condition of taking water as a solvent and shows excellent catalytic performance, and after 50 times of application, the acetophenone conversion rate is gt; the selectivity of alpha-phenylethylamine is gt; the selectivity of the alpha-phenethyl alcohol is 1t; and 2%.
Owner:WANHUA CHEM GRP CO LTD

Catalyst for catalyzing selective oxidation of ethylbenzene to prepare acetophenone as well as preparation method and application of catalyst

The invention relates to a catalyst for preparing acetophenone by efficiently catalyzing selective oxidation of ethylbenzene in a hydrocarbon selective oxidation reaction, especially under a mild condition, a preparation method of the catalyst, and application of the catalyst provided by the invention. According to the catalyst for catalyzing selective oxidation of ethylbenzene to prepare acetophenone, monatomic Fe is anchored on a nitrogen-doped carbon carrier through a Fe-Nx coordination bond, the Fe content is 4-23 wt%, the BET specific surface area is 200-500 m / g, and Fe exists in Fe < + > and Fe < + > valence states. The catalyst can be used for preparing acetophenone through selective oxidation of hydrocarbons and has the advantages of being high in catalytic performance, stable in structure and good in substrate universality.
Owner:YANTAI ADVANCED MATERIALS & GREEN MFG SHANDONG PROVINCIAL LAB

Anti-ultraviolet functional plastic particles and preparation method thereof

PendingCN121450029APolymer sciencePolyolefin
The invention discloses an anti-ultraviolet functional plastic particle and a preparation method thereof, and belongs to the technical field of polymer modified materials. The plastic particles are prepared from polyolefin resin subjected to organic silicon-phenolic hydroxyl synergistic grafting modification, 2, 4-dihydroxyacetophenone, an antioxidant, a hindered amine light stabilizer, a lubrication dispersant and an anti-yellowing agent. A siloxane-phenolic hydroxyl bifunctional chain segment is introduced into the surface of a molecular chain of the polyolefin resin subjected to organic silicon-phenolic hydroxyl synergistic grafting modification, so that a flexible-rigid synergistic interface layer is formed; the 2, 4-dihydroxyacetophenone has a hydroxyl and carbonyl conjugated structure and can form hydrogen bond complexation with a matrix, so that free radical degradation is effectively inhibited. The preparation method disclosed by the invention comprises the following three steps: grafting reaction of polyolefin resin subjected to organic silicon-phenolic hydroxyl synergistic grafting modification, high-speed mixing and melt blending granulation. Tests show that after the plastic particles are subjected to 365nm ultraviolet radiation for 500h, the tensile strength retention rate exceeds 94%, the chromatic aberration delta E is less than or equal to 1.5, the oxidation induction time is prolonged to 55min, and the plastic particles have excellent ultraviolet aging resistance, yellowing resistance and thermal oxidation stability.
Owner:SHENZHEN JIANCAI TECH DEVING

Detergents and cleaning compositions having improved degreasing power

The present invention relates to detergents and cleaning compositions comprising a degreasing agent, an effective amount of a specific type of degreasing enhancer, such as an alkanediol having a carbon chain of 5 to 14 carbon atoms, glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or a mixture of the aforementioned degreasing enhancers, and a surfactant, as well as the use of the aforementioned detergents and cleaning compositions for preparing detergents and cleaning products for household, institutional and industrial applications. Furthermore, the present invention relates to methods for treating stained and / or soiled substrates using the detergents and cleaning compositions according to the present invention. In addition, the present invention relates to the use of specific enhancing substances, as defined herein, for enhancing the degreasing power of degreasing detergents and cleaning compositions and for improving the cleaning performance of degreasing detergents and cleaning compositions. Furthermore, the present invention relates to a method for enhancing the degreasing power of degreasing detergents and cleaning compositions and improving the cleaning performance of degreasing detergents and cleaning compositions by adding an effective amount of a specific degreasing enhancer, for example, an alkanediol having a carbon chain of 5 to 14 carbon atoms, glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or a mixture of the aforementioned degreasing enhancers, to the aforementioned detergents and cleaning compositions. Finally, the present invention relates to the use of at least one degreasing enhancer, for example, an alkanediol as defined herein, glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or a mixture of the aforementioned degreasing enhancers as defined herein, as a substitute for a degreasing agent and / or a solubilizer.
Owner:SYMRISE GMBH & CO KG

Wrinkle-removing cream containing sequoia stem fermentation product and preparation method of wrinkle-removing cream

PendingCN121512898ACosmetic preparationsToilet preparationsEthylhexyl palmitateButanediol
The invention relates to the technical field of cosmetics, and particularly discloses anti-wrinkle cream containing sequoia stem fermentation products and a preparation method of the anti-wrinkle cream. The wrinkle removing cream containing the sequoia stem fermentation product is prepared from the following raw materials in percentage by mass: a material A: glycerol, butanediol, p-hydroxyacetophenone YS028, an ammonium acryloyldimethyl taurate / VP copolymer, p-hydroxyacetophenone YS008 and the balance of water; the material B is prepared from cetostearyl alcohol, an emulsifying agent MONTANOV202, butyrospermum parkii butter, isopropyl myristate, C10-18 fatty acid triglyceride, polydimethylsiloxane, ethylhexyl palmitate and XIAMETERPMX-0345Z Fluid; the material C is prepared from a material D and a material E; the material C is prepared from a sequoia stem fermentation product, Naturalpenet 2020 and SEPIGEL305; the material D is prepared from YONOME SPE II, Alps mountain leucas, ULA-L1004 coated ceramide, anti-wrinkle base peptide, super-oinmetidyl-D2, Chinese prescription hexyl A powder, XYREPIOR, annoine TM, essence and methyl dihydrojasmonate; the material D is prepared from YONOME SPE II, Alps mountain leucas, ULA-L1004 coated ceramide, anti-wrinkle base peptide, super-oinmetidyl-D2, Chinese prescription hexyl A powder, XYREPIOR, annoine TM In addition, the preparation method has the advantage of improving the wrinkle removing effect of the wrinkle removing cream.
Owner:SHANDONG YUSEN BIOTECHNOLOGY CO LTD

A double mannich base type corrosion inhibitor and its preparation method and application

The application relates to the field of CO2 utilization and storage technology, and discloses a double Mannich base corrosion inhibitor as well as a preparation method and application thereof. The method is carried out under the condition that the pH is 3-4; the method comprises the following steps: (1) in the presence of ethanol, a compound shown in formula (A) is subjected to a first reaction with 1,3,5-trioxane to obtain an intermediate product; in formula (A), R is -(CH2)7CH=CH(CH2)7CH3; (2) in the presence of ethanol, the acetophenone is added dropwise into the intermediate product to carry out a second reaction, so that the double Mannich base corrosion inhibitor is obtained; the dropwise speed of the acetophenone is 0.0125-0.05 mL / s relative to 1 mol of the compound shown in formula (A); wherein the molar ratio of the compound shown in formula (A), the acetophenone and the 1,3,5-trioxane is 1:2.0-2.3:2.0-2.3. Formula (A).
Owner:SHANDONG PETROCHEMICAL INST +2

Method for improving stability of sialic acid-p-hydroxyacetophenone solution

The invention relates to the technical field of cosmetics, in particular to a method for improving the stability of a sialic acid-p-hydroxyacetophenone solution. The method comprises the following steps: mixing p-hydroxyacetophenone with a stabilizer, and then mixing with sialic acid to obtain sialic acid-p-hydroxyacetophenone mixed liquor; the stabilizer is sulfite and / or hydrosulfite, and the addition amount of the stabilizer is 0.005%-0.2% by mass. Aiming at the problems of discoloration of sialic acid-p-hydroxyacetophenone solution and loss of sialic acid, the invention provides a method, all the raw materials are mixed according to a specific sequence on the basis of a specific stabilizer through a specific processing technology, the stability of the obtained solution is remarkably improved, the solution does not discolorate after being placed for a long time, the loss rate of sialic acid is low, and the method is suitable for industrial production. The method has important application value in the field of production of cosmetics containing sialic acid at the same time.
Owner:WUHAN ZHONGKE OPTICS VALLEY GREEN BIOTECHNOLOGY CO LTD

Bis-Mannich base corrosion inhibitor as well as preparation method and application thereof

ActiveCN121974855AGood high temperature resistance and corrosion inhibition performancereduce dosageOrganic chemistryDrilling compositionCombinatorial chemistryAcetophenone
The invention relates to the technical field of CO2 utilization and storage, and discloses a bis-Mannich base corrosion inhibitor as well as a preparation method and application thereof. The method is carried out under the condition that the pH is 3-4. The method comprises the following steps: (1) in the presence of ethanol, carrying out first reaction on a compound as shown in a formula (A) and 1, 3, 5-trioxane to obtain an intermediate product; in formula (A), R is-(CH2) 7CH = CH (CH2) 7CH3; and (2) in the presence of ethanol, dropwise adding acetophenone into the intermediate product for a second reaction to obtain the bis-Mannich base corrosion inhibitor, the dropping rate of acetophenone is 0.0125-0.05 mL / s relative to 1 mol of the compound as shown in the formula (A); wherein the molar ratio of the compound shown in the formula (A) to the acetophenone to the 1, 3, 5-trioxane is 1: (2.0-2.3): (2.0-2.3). Formula (A).
Owner:SHANDONG PETROCHEMICAL INST +2

Anti-inflammatory repairing skin care compound and preparation method thereof

PendingCN121796297ACosmetic preparationsToilet preparationsPalmitoyl tetrapeptideGlycerol
The invention relates to the technical field of skin care products, in particular to an anti-inflammatory repairing skin care compound and a preparation method thereof. The anti-inflammatory repairing skin care compound is prepared from the following components in percentage by mass: 10 to 15 percent of ganoderma lucidum extract, 5 to 10 percent of ginseng extract, 2 to 3 percent of radix angelicae powder, 3 to 5 percent of aloe vera gel, 5 to 8 percent of 4D hyaluronic acid, 8 to 12 percent of glycerol, 0.2 to 0.5 percent of p-hydroxyacetophenone, 2 to 3 percent of palmitoyl tetrapeptide-7, 0.5 to 1.2 percent of allantoin, 0.5 to 1 percent of bisabolol, 2 to 4 percent of asiaticoside and 3 to 5 percent of functional additive, 1-2% of an antioxidant, 1-2% of a thickening agent, 0.5-1% of an emulsifier, 0.2-0.5% of a chelating agent and the balance of deionized water; the anti-inflammatory repair skin care compound prepared by the invention not only has excellent anti-inflammatory soothing and moisturizing effects, but also has good repair and anti-oxidation effects on the skin, so that the skin aging speed is delayed to a certain extent, and the product quality is effectively ensured.
Owner:肖年生

Efficient preparation method of allyl amine compound

The invention relates to a synthesis method of an allyl amine compound. According to the method, 2-methylquinoline or acetophenone derivatives are used as raw materials, a selective fluorine reagent Selectfluor is used as an accelerant, dimethyl sulfoxide and N 'N-dimethylacetamide are used as a mixed solvent, and the allyl amine series compounds are prepared with high yield. The preparation method has the advantages of being low in cost, easy to operate, green, free of pollution and the like, and has potential industrial application prospects. The method provides a green, cheap and convenient way for preparing the allyl amine derivative by using 2-methylquinoline or acetophenone compounds as initiators.
Owner:JILIN UNIVERSITY

Lanthanum cobalt composite catalyst, and preparation method and application thereof

The application discloses a lanthanum-cobalt composite catalyst and a preparation method and application thereof. The lanthanum-cobalt composite catalyst is composed of La2O2SO4, Co4S3 and Co3O4. Co(NO3)2.6H2O, La(NO3)3.6H2O, urea and sodium dodecyl sulfate are dissolved in an isopropyl alcohol solution to form a reaction solution, a precursor is obtained through a solvothermal method, and the lanthanum-cobalt composite catalyst is prepared through calcination. The prepared catalyst is used for selectively oxidizing ethylbenzene into acetophenone under the condition that molecular oxygen is used as an oxidant and no solvent is used, and excellent catalytic performance is shown. The catalytic system meets the requirements of green chemical industry and sustainable development.
Owner:YANGZHOU UNIV

Snowflake cream with pearly luster and preparation process thereof

The invention discloses snowflake cream with pearly luster and a preparation process of the snowflake cream. The snowflake cream comprises the following raw material components: a phase A: water; butanediol; glycerol; methyl glucitol polyether-20; a polyacrylate cross-linked polymer-6; sodium hyaluronate; potassium hydroxide (90%); 4-hydroxyacetophenone; xanthan gum; phase B: caprylic / capric triglyceride; cetostearyl alcohol; stearic acid; a polydimethylsiloxane; squalane; simmondsia chinensis seed oil; mineral oil; and polyethylene glycol (PEG)-100 stearate. Glyceryl stearate; tocopheryl acetate; isononyl isononanoate; a phase C: 1, 2-hexanediol; carnosine; a centella asiatica extract; collagen; the snowflake cream has the advantages of uniform pearly luster texture and the advantages of traditional snowflake cream.
Owner:SUZHOU ANTE COSMETICS CO LTD

Preparation and application of a tetraphenyl ethene-chalcone derivative

The application discloses a kind of tetraphenyl ethylene-chalcone derivative preparation and its application preparation and its application.The structure is as follows: the method includes: 4-(1,2,2-triphenyl ethenyl) acetophenone, aldehyde derivative, sodium hydroxide (provides alkaline condition, pH=8.3~8.5), is placed in anhydrous ethanol, under the condition that heating temperature is 80 DEG C, reflux reaction 12h, after reaction is ended, the functional organic material is separated and purified.The functional organic material synthesized according to the above method has larger conjugated system, and has significant pressure-induced color change characteristics.The functional organic material disclosed in the application has low preparation cost, simple operation, simple method, and the material shows significant pressure-induced color change characteristics, can be applied to pressure-induced color change, luminescent material, printing and dyeing, color printing and anti-counterfeiting technical field.
Owner:CHINA THREE GORGES UNIV

Key intermediate of lotinib and preparation method of key intermediate

The invention belongs to the field of medical intermediate compounds and organic synthesis, and particularly relates to a key intermediate of lotinib and a preparation method thereof, the preparation method comprises the following steps: (1) in an organic solvent, organic alkali, 2-cyanoethyl 5-acetyl-3-methylthiophene-2-carboxylic ester and 2, 2, 2-trifluoro-1-(3, 4, 5-trichlorobenzene) ethanone react to obtain an intermediate 1; (2) dehydrating the intermediate 1 into double bonds to obtain an intermediate 2; and (3) reacting the intermediate 2 with a ligand to obtain the key intermediate of lotinib. The intermediate is used for synthesizing lotinib. The preparation method provided by the invention has the advantages of extremely high chiral selectivity, mild conditions and stable yield, can be suitable for amplified production, and provides a new technology suitable for industrial production for the key intermediate of lotinia.
Owner:SHANDONG CHENGCHUANG BLUE OCEAN PHARM TECH CO LTD

Method for co-production of 2, 4-dichloro-5-fluoroacetophenone and hydroxylamine hydrochloride

ActiveCN121895131Ahigh yieldhigh purityHydroxylamineOximes preparationHydroxylamineN-butyl nitrite
The invention discloses a method for co-production of 2, 4-dichloro-5-fluoroacetophenone and hydroxylamine hydrochloride, and belongs to the technical field of organic chemical industry, 2, 4-dichlorofluorobenzene is used as a raw material, alkylation and reaction with tert-butyl nitrite are performed to generate oxime, and then hydrochloric acid hydrolysis is performed to generate 2, 4-dichloro-5-fluoroacetophenone and hydroxylamine hydrochloride; according to the method, co-production of the 2, 4-dichloro-5-fluoroacetophenone and the hydroxylamine hydrochloride is innovatively realized, not only are high yield and high purity of the target product 2, 4-dichloro-5-fluoroacetophenone ensured, but also the nitrogen element in the reaction is recycled and converted into the hydroxylamine hydrochloride with high additional value, and the atom economy is remarkably improved; according to the method, the operation process is greatly simplified, the use of dangerous reagents is avoided, and the intrinsic safety and environmental friendliness of the process are improved from the source; the method is simple to operate, safe and environment-friendly, the production cost is effectively reduced, and the market competitiveness of the product is enhanced.
Owner:SHANDONG GUOBANG PHARMA +1

Moisturizing and soothing cosmetic containing artemisia apiacea extract and preparation method thereof

PendingCN121550105ACosmetic preparationsToilet preparationsChamomile extractButanediol
The invention discloses a moisturizing and soothing cosmetic containing an artemisia apiacea extract and a preparation method of the moisturizing and soothing cosmetic. The cosmetic is prepared from the following raw materials in percentage by weight: 0.5%-2% of 1, 2-hexanediol, 0.3%-1% of p-hydroxyacetophenone, 5%-15% of butanediol, 0.1%-1% of dimethyl sulfone, 0.3%-2% of zanthoxylum armatum extract, 0.2%-1.5% of aesculus chinensis extract, 0.1%-0.5% of dipotassium glycyrrhizinate, 0.5%-3% of panthenol, 0.1%-0.8% of allantoin, 0.1%-1% of oat beta-glucan, 0.05%-0.5% of hydrolyzed sodium hyaluronate, 0.001%-0.01% of caramel color, 0.1%-1% of cyclodextrin, 0.05%-0.3% of acetyl dipeptide-1 cetyl ester, 0.5%-2.5% of scutellaria baicalensis extract, 0.3%-2% of purslane extract and 0.2%-1.5% of a chamomile extract and the balance of deionized water. The traditional Chinese medicine composition has the advantages that various extracts are in synergistic interaction; the safety is high; the composition is suitable for sensitive skin, dry skin and other skin types, and can be prepared into emulsion, face cream, essence and other dosage forms.
Owner:GUANGZHOU XIXIANG COSMETICS CO LTD

Detergents and cleaning compositions having improved cleaning performance

The present invention relates to detergents and cleaning compositions comprising an enzyme, an effective amount of a particular type of enzyme enhancer, such as an alkanediol having a carbon chain of 5 to 14 carbon atoms, glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or a mixture of the aforementioned enzyme enhancers, and a surfactant, as well as the use of the aforementioned detergents and cleaning compositions for preparing detergents and cleaning products for household, institutional and industrial applications. Furthermore, the present invention relates to a method for treating stained and / or soiled substrates using the enzyme detergents and cleaning compositions according to the present invention. In addition, the present invention relates to the use of certain substances, as defined herein, for enhancing the performance of enzymes in detergents and cleaning compositions and / or for improving the cleaning performance of detergents and cleaning compositions. Finally, the present invention relates to a method for enhancing the enzyme performance in detergents and cleaning compositions and / or improving the cleaning performance in detergents and cleaning compositions by adding an effective amount of a specific enzyme enhancer, for example, an alkanediol having a carbon chain of 5 to 14 carbon atoms, glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or a mixture of the aforementioned enzyme enhancers, to the aforementioned detergents and cleaning compositions.
Owner:SYMRISE GMBH & CO KG

A soothing repair efficacy composition and use thereof

ActiveCN116421493BCosmetic preparationsToilet preparationsArgininePolygonum cuspidatum root extract
This invention discloses a soothing and repairing composition and its application, comprising the following raw materials: phytosterols, chamomile extract, hydrolyzed sodium hyaluronate, tocopherol, ceramide NP, triethanolamine, lactobacillus, macadamia seed oil, magnolia alcohol, matricaria flower extract, maltodextrin, lecithin, phosphatidylcholine, ascorbyl palmitate, inulin root juice, arginine / lysine polypeptide, squalane, jojoba seed oil, scutellaria baicalensis root extract, polygonum cuspidatum root extract, fructose, glycerin, p-hydroxyacetophenone, butylene glycol, acrylate / C10-30 alkanol acrylate crosspolymer, α-glucan oligosaccharide, 1,2-hexanediol, and water as the balance. Compared with the prior art, the soothing and repairing composition prepared by this invention has the effects of rapidly rebuilding the skin barrier, regulating skin immune function, improving skin microecology, synergistic effect, and rapid skin repair.
Owner:SHANGHAI YANYU MEDICAL TECH CO LTD

A method for preparing an etoricoxib intermediate

This invention is entitled "A Method for Preparing an Intermediate of Aericoxib," belonging to the field of pharmaceutical preparation technology. The technical problem to be solved is to provide a method for preparing an intermediate of Aericoxib that is simple to operate, uses readily available raw materials, and has simple post-processing. The key points of the technical solution are that the preparation method includes the following steps: (1) 2-bromo-1-(4-methanesulfonyl)acetophenone, hexamethylenetetramine and solvent are reacted, filtered, hydrochloric acid and methanol are added, and the reaction is continued to obtain 2-amino-1-(4-methanesulfonyl)acetophenone hydrochloride; (2) 2-amino-1-(4-methanesulfonyl)acetophenone hydrochloride, p-methylphenylacetic acid, base 1 and solvent are mixed, reacted, cooled to -5℃-15℃, base 2 and 1-bromopropane are added, and the reaction is continued to obtain the intermediate.
Owner:CHANGZHOU YABANG PHARMA

A fluorine-containing dihydronaphthone derivative, a preparation method and application thereof

The present application relates to a kind of fluorine-containing dihydronaphthalenone derivative and its preparation method and application, the fluorine-containing dihydronaphthalenone derivative obtained by visible light induced phosphine catalysis difluoroacetophenone derivative and the radical addition cyclization reaction of a variety of olefins in series compared with prior art, the preparation method of the present application has the advantages of high efficiency, short reaction time, high yield, mild condition etc., its structural motif is important in pharmaceutical and agrochemical products;The synthetic method for preparing fluorine-containing dihydronaphthalenone and its derivative of the present application is completely new, and the fluorine-containing dihydronaphthalenone compound synthesized is used in various organic synthesis reactions.
Owner:SHANGHAI INST OF TECH

Electrophotographic photoreceptor

PendingUS20260202772A1M-aminoacetophenoneAcyl group
An electrophotographic photoreceptor includes: a conductive base, a photosensitive layer provided on the conductive base, and a protective layer provided on the photosensitive layer. The protective layer is a cured body of a photocurable composition that includes a photocurable compound and a photopolymerization initiator. The photopolymerization initiator includes a first compound having an acylphosphine oxide structure and a second compound having an α-aminoacetophenone structure and an absorption coefficient at a wavelength 365 nm smaller than that of the first compound. A total content of the first compound and the second compound with respect to 100 parts by mass of the photocurable compound is 5 parts by mass or more and 20 parts by mass or less.
Owner:KYOCERA DOCUMENT SOLUTIONS INC

Preparation method for cannflavin compounds

Disclosed is a preparation method for cannflavin compounds. The preparation method has the advantages of cheap and easily available raw materials, few reaction steps, short production period, simple operation, etc. The method comprises: firstly, condensing 4′-hydroxy-3′-methoxyacetophenone and diethyl carbonate (DEC) under an alkaline condition to obtain 4′-hydroxy-3′-methoxybenzoyl acetate; reacting 1,3,5-trihydroxybenzene with bromo-isoamylene under an alkaline condition to obtain 2-isopentenyl-1,3,5-trihydroxybenzene; and finally, condensing 4′-hydroxy-3′-methoxybenzoyl acetate and 2-isopentenyl-1,3,5-trihydroxybenzene at a high temperature to produce cannflavin B and / or isocannflavin B, and then subjecting same to separation and purification to obtain pure cannflavin B and pure isocannflavin B.
Owner:DEYI PHARMA LTD

Chalcone and flavanone sulfamide derivatives, synthesis method and application thereof

This invention discloses 2'-hydroxy-4,4',6'-trimethoxychalcone and 5,7,4'-trimethoxyflavanone sulfonamide derivatives, their synthesis methods and applications, belonging to the field of pharmaceutical technology, and involving two series of compounds: 3-sulfonamido-2'-hydroxy-4,4',6'-trimethoxychalcone and 8,3'-disulfonamido-5,7,4'-trimethoxyflavanone, and their preparation methods. Starting with 2-hydroxy-4,6-dimethoxyacetophenone and p-anisaldehyde or 4-methoxy-3-nitrobenzaldehyde, 2'-hydroxy-4,4',6'-trimethoxychalcone or 3-amino-2'-hydroxy-4,4',6'-trimethoxychalcone intermediates were synthesized via the Claisen-Schmidt reaction. Then, through sulfonation and intramolecular Michael addition reactions, 2'-hydroxy-4,4',6'-trimethoxychalcone and 5,7,4'-trimethoxyflavanone sulfonamide derivatives were synthesized. The preparation method is simple, mild, and yields high results. In vitro and in vivo activity tests show that the derivatives disclosed in this invention have significant in vitro inhibitory activity against gastric cancer, esophageal cancer, colorectal cancer, and lung cancer cell lines, acting as inhibitors of the protein YBX1 / RPN1. Clinically, they can be applied to targeted therapy for cancers such as gastric cancer, esophageal cancer, colorectal cancer, and lung cancer.
Owner:ZHENGZHOU UNIV

A method for preparing a bromotrifluoromethylsulfinylacetophenone

The application discloses a preparation method of bromo-trifluoromethylthioacetophenone and belongs to the field of chemical synthesis. The application provides a novel method for the bromo-trifluoromethylthio substitution of the bifunctionalization reaction of styrene, and the easily obtained trifluoromethylthio silver and bromine water are used as the trifluoromethylthio source and the bromine source, respectively, the substrate has wide applicability, and the raw material is simple and easy to obtain. In addition, the method can realize the synthesis of the target product, and the target product can be obtained in a good yield in 2-12 hours, and the method is more rapid and efficient. The synthesis method can synthesize the bromo-trifluoromethylthioacetophenone compound under relatively simple conditions by using the simple and easily obtained aryl olefin, realizes the bromo-trifluoromethylthio bifunctionalization of the styrene, and converts the styrene into the fluorine-containing building block compound which has wide application in the fields of medicine, pesticide and petroleum chemical industry.
Owner:JIANGNAN UNIV

A soothing anti-wrinkle moisturizing emulsion and a method of making the same

The application belongs to the technical field of cosmetics, and specifically discloses a soothing anti-wrinkle moisturizing emulsion and a preparation method thereof, which comprises the following components in a mass percentage: 0.02-0.12% of a chelating agent, 4-8% of a humectant, 0.2-0.6% of a thickening agent, 0.5-2% of dragon fruit stem polysaccharide, 5-15% of dragon fruit seed oil, 0.3-1% of tocopheryl acetate, 1-3% of an emulsifier, 0.02-0.1% of rose essential oil, 5-10% of dragon fruit peel extract, 0.3-0.5% of p-hydroxyacetophenone, 0.5-1% of 1,2-hexanediol, 0.02-0.1% of a pH regulator, and the balance of deionized water. The soothing anti-wrinkle moisturizing emulsion of the application adds natural dragon fruit stem polysaccharide, dragon fruit seed oil and dragon fruit peel extract, and the components are green and natural, do not contain essence, pigment and preservative, and are truly safe, effective, mild and non-irritating.
Owner:GUANGZHOU HUATAI BIOTECHNOLOGY CO LTD

Application of compounds in attracting or controlling midges

PendingCN122074489ARich candidate resourcesreduce population densityBiocidePest attractantsDiseaseButyrate
This invention provides the application of compounds in attracting or controlling midges, relating to the field of midge control technology. Through screening and identification, this invention has obtained five compounds (butyric acid, butyraldehyde, propionaldehyde, 2-hexanone, and acetophenone) with significant attractant activity against Formosan midge. These compounds can be used alone or in combination, are environmentally friendly and have a high affinity for non-target organisms, greatly enriching the candidate resource of midge attractants. They can be directly applied to the monitoring and large-scale trapping of midges, effectively reducing midge population density, thereby reducing midge bites and the spread of midge-borne diseases, which has significant public health implications.
Owner:SHENZHEN BAY LAB

Batching device for producing p-hydroxyacetophenone

The invention discloses a batching device for producing p-hydroxyacetophenone, and particularly relates to the technical field of p-hydroxyacetophenone production, the batching device comprises a batching tank body, the top of the batching tank body is provided with eight feeding channel openings, and feeding mechanisms are arranged on the eight feeding channel openings; the feeding mechanism comprises a fixed rack, the fixed rack is welded to the inner wall of one side of a feeding channel opening in the corresponding position, a carrying base plate is hinged to one side of the fixed rack, the carrying base plate is arranged in the feeding channel opening, and a pressure sensor is arranged on the carrying base plate. Through the arrangement of the feeding mechanism, the automatic batching device has the functions of precise weighing of fed materials and automatic discharging, during batching, a worker only needs to carry out feeding according to reminding of an indicator lamp, operation is simple, additional weighing and operation of pouring raw materials into batching equipment are not needed, the time needed for batching is greatly shortened, the batching speed is high, and the work efficiency is improved. And the actual use effect of the device is relatively good.
Owner:NINGXIA HUAYI NEW MATERIAL TECH CO LTD

Application of 2, 4-dihydroxy-6-methoxyacetophenone in preparation of medicine for treating lacrimal gland secretion dysfunction related diseases

The application is a divisional application of 2025116336025, the invention provides an application of 2, 4-dihydroxy-6-methoxyacetophenone in preparation of a medicine for treating lacrimal gland secretion dysfunction related diseases, a lacrimal gland dysfunction dry eye mouse model is constructed in the application, and liposome entrapped 2, 4-dihydroxy-6-methoxyacetophenone is adopted for intervention, so that the medicine for treating lacrimal gland secretion dysfunction related diseases is obtained. Experimental results show that the ocular surface function and structure of a model animal are remarkably improved through treatment of 2, 4-dihydroxy-6-methoxyacetophenone, the cornea sodium fluorescein staining score of a mouse in a 2, 4-dihydroxy-6-methoxyacetophenone treatment group is remarkably reduced, and cornea epithelium injury is effectively repaired; the epithelial structure in the cornea tissue tends to be complete, and inflammatory cell infiltration of a matrix layer is obviously relieved; the density of goblet cells in the conjunctiva is obviously increased, which indicates that the secretion function of the mucous layer on the ocular surface is recovered. The treatment of 2, 4-dihydroxy-6-methoxyacetophenone has an improvement trend on tear film rupture time and tear secretion amount, which indicates that the 2, 4-dihydroxy-6-methoxyacetophenone has a potential effect in the aspects of maintaining tear film stability and promoting basic tear secretion.
Owner:AFFILIATED HOSPITAL OF NANTONG UNIV

Curable resin compositions

Some of the resin compositions are ultraviolet light or thermally curable, while others are ultraviolet light curable. One example of the ultraviolet light or thermally curable resin composition consists of a predetermined mass ratio of a (meth)acrylate cyclosiloxane monomer and a non-siloxane (meth)acrylate based monomer ranging from about >0:<100 to about 80:20; from 0 mass % to about 10 mass %, based on a total solids content of the resin composition, of an initiator selected from the group consisting of an azo-initiator, an acetophenone, a phosphine oxide, a brominated aromatic acrylate, and a dithiocarbamate; a surface additive; and a solvent.
Owner:ILLUMINA INC