1967 results about "Acetophenone" patented technology

A polymerizable composition contains (A) a polymerization initiator that is an acetophenone-based compound or an acylphosphine oxide-based compound, (B) a polymerizable compound, (C) at least either a tungsten compound or a metal boride, and (D) an alkali-soluble binder.

Solvent mixtures useful for processing bulk heterojunction materials and methods for selecting the same are disclosed, wherein Hansen solubility parameters are utilized to select the solvent mixture. A solvent system using a fully nonhalogenated solvent mixture is disclosed. Also disclosed is a solvent mixture containing 20 vol. % acetophenone (AP) in mesitylene (MS), wherein the performance of the solvent system is comparable to dichlorobenzene.

An ink set for inkjet recording is provided that includes at least a colored liquid composition comprising at least a radically polymerizable compound, a photopolymerization initiator, and a colorant, and an undercoat liquid composition comprising at least a radically polymerizable compound and a photopolymerization initiator, the colored liquid composition comprising as the photopolymerization initiator at least one type of α-aminoacetophenone compound, and the undercoat liquid composition comprising as the photopolymerization initiator at least one type of compound selected from the group consisting of an acylphosphine oxide compound, an α-hydroxyacetophenone compound, and an oxime ester compound. There is also provided an inkjet recording method employing the ink set for inkjet recording, the method including a step of applying the undercoat liquid composition on top of a recording medium, a step of semi-curing the undercoat liquid composition, and a step of carrying out image formation by discharging the colored liquid composition on top of the semi-cured undercoat liquid composition.

The invention discloses a synthetic method for loxoprofen sodium, which is prepared by taking methyl acetophenone as an initial raw material through reduction, acylation or halogen substituent, cyanation, hydrolysis, bromination, condensation, decarboxylation and salifying. The method has the advantages of easily obtained raw material, unique technology, simple and stable operation, and high productive rate in each step of reaction; and all solvents used in the synthesis process can be recycled, so the production cost is reduced greatly. Tests show that the obtained product has reliable quality and stable performance, and can be further used for making preparation of non-steroidal anti-inflammatory drugs such as the loxoprofen sodium.

The present invention belongs to the field of chemical technology, and is new type of amorphous catalyst for acetophenone hydrogenating process to prepare phenethyl alcohol and its preparation process. The catalyst consists of Ni, B, metal additive M and carrier material L, where, Ni exists mainly in Ni-B or Ni-M-B amorphous alloy form and the metal additive M is one of Sn, Cr, Mo, W, Fe, Co and La. The catalyst is prepared through reducing metal ion and subsequent impurity elimination. The catalyst is used for acetophenone hydrogenating process to prepare phenethyl alcohol, and has simple preparation process, relatively low cost and much higher acetophenone hydrogenating activity and selectivity compared with traditional industrial Rancy Ni catalyst.

Relating to an enzyme capable of efficiently converting a ketone compound to an optically active amino compound by transamination, and a process for preparing an optically active amino compound using the enzyme. An (S)-alpha-phenethylamine:pyruvate transaminase, which acts on (S)-alpha-phenethylamine and a ketone compound, thereby catalyzing transamination for forming acetophenone and an amino compound corresponding to the ketone compound; a process for preparing an optically active amino compound using the transaminase; and a method for culturing a microorganism for producing the above transaminase, comprising adding to a medium one or more compounds selected from the group consisting of propylamine, 1-butylamine, 2-butylamine, 2-pentylamine, isopropylamine and isobutylamine as an inducer for the enzyme when a microorganism for producing (S)-alpha-phenethylamine:pyruvate transaminase is cultured.

A therapeutic agent and prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for an insulin-mimetic action, a food, beverage and feed, an agent for enhancing glucose uptake into a cell, and an agent for inducing differentiation into an adipocyte, characterized in that each comprises as an effective ingredient at least one compound selected from the group consisting of a chalcone compound, an acetophenone compound, a coumarin compound, a phthalide compound, derivatives thereof, and pharmacologically acceptable salts thereof.

The invention discloses a preparation method of propiconazole that is a bactericide, which comprises four steps: first of all, under the action of an acid catalyst, atmospheric refluxing dehydration is carried out to 2, 4-dichloroacetophenone and 1, 2-pentanediol which are in an organic solvent so as to obtain ketal reaction solution which then reacts with bromine to generate bromide ketal which then reacts with 1, 2, 4- triazole sylvite in a polar solvent under the action of a phase transfer catalyst to obtain a propiconazole crude product; finally, under the action of an antioxidant, the propiconazole crude product is distilled under high vacuum and high temperature to obtain the propiconazole finished product. The preparation method of the invention reduces the varieties and dosage of the solvents necessary for reactions as well as the yield of wastewater resulted from cleaning during the reactions, thus realizing the goal of clean production.

The invention relates to a mixture of compounds having the sensory properties of winter-green, to fragrance and flavoring compositions containing said mixture and to flavored and perfumed products containing said mixture, to a method of adding a wintergreen flavor, odor or note to (non-wintergreen) flavored or perfumed products. Further the present invention relates to the use of said mixture as an enhancement, or as complete or partial replacement for methyl salicylate, in particular in chewing gum, foods, dentrifices, mouthwashes and other orally consumable products. The mixture comprises or consists of dihydroanethole, o-anisaldehyde, 1,3-dimethoxybenzene, 2′-hydroxyacetophenone, and optionally 2-methoxyacetophenone.

A diode-addressed color display comprising an UV-diode and a phosphor of the general formula LnL3X2, wherein Ln=Eu3+, Tb3+, Tm3+, Dys3+, Sm3+, L=4-R-4'-benzophenone carboxylic acid, wherein R=phenyl, benzyl, CH3, CF3, C2H5, F, Cl, OCH3, CH3CO; 4-R-4'-benzophenone acetylacetonate, wherein R=phenyl, benzyl, CH3, CF3, C2H5, F, Cl, OCH3, CH3CO; 4-acetophenone carboxylic acid, 4-trifluoroacetophenone carboxylic acid, 4-acetophenone acetylacetonate or 4-trifluoroacetophenone acetylacetonate and X=+E,fra 1/2+EE phenanthroline, +E,fra 1/2+EE diphenyl phenanthroline, +E,fra 1/2+EE 4-Cl-phenanthroline, +E,fra 1/2+EE bipyridine, +E,fra 1/2+EE ethylenediamine, triphenyl phosphineoxide, trimethyl phosphineoxide, triethyl phosphineoxide, +E,fra 1/2+EE diethylene glycol-dimethylether (diglyme) or ethanol.

The invention discloses a method for synthesizing alpha-bromo acetophenone compound, which comprises the steps: hydrosulphite solution is added into the mixture of substituted phenylethanone and bromate at the temperature of 30-90 DEG C, and the mixture is stirred to react for 2-9h, and then is cooled, filtered, washed and dried, so that the alpha-bromo acetophenone compound is obtained. The method also has the advantages that the product has high product purity, the price of bromide reagent is low, aqueous phase is solvent instead of organic solvent, the pollution is little, the operation is simple, and the method is suitable for mass production.

The invention discloses a chiral tridentate PNN ligand and application of the same in asymmetric hydrogenation and similar reactions. The tridentate nitrogen phosphine ligand disclosed in the invention has been the first reported nitrogen phosphine ligand containing chiral oxazoline so far and has been successfully applied to high-efficiency and high-selectivity hydrogenation and similar reactions of ketone and imine salts. Compared with other ligand, the ligand provided by the invention is simpler in synthetic route, higher in yield and environment-friendlier; moreover, the metal complex of the ligand shows better selectivity and a higher turn-over number in asymmetric hydrogenation. An iridium complex of the chiral tridentate PNN ligand has successfully realized asymmetric reduction of beta-ketone ester into beta-alcohol ester (which is a raw material for synthesis of molecular drugs duloxetine and atomoxetine), asymmetric hydrogenation of alpha-hydroxyacetophenone into alpha-hydroxyphenylethyl alcohol and asymmetric hydrogenation of acetophenone into phenylethyl alcohol, which is of important significance to production of the medical industry.

The invention discloses a method for preparing acetophenone by oxidizing ethylbenzene in a continuous flow micro-channel reactor, which belongs to the technical field of application of organic synthesis, and relates to a novel process for synthesizing acetophenone within the reaction time of dozens of seconds to certain minutes in the continuous flow micro-channel reactor by taking ethylbenzene as a raw material, taking a low-boiling-point common solvent and a cobalt salt as catalysts and taking hydrogen peroxide as an oxidant. Acetophenone serving as a product is obtained lastly by pumping two paths of reaction raw materials into the micro-channel reactor with a metering pump and preheating and reacting. The method is easy and convenient to operate, continuous production of acetophenone at high yield becomes possible, and the process has low environmental pollution. The ethylbenzene transformation ratio is 20-60 percent, and the selectivity of acetophenone is 85-100 percent.

The invention discloses an oxidation method of acetophenone. According to the method, under oxidation reaction conditions, acetophenone, an oxidant, a solvent and a catalyst are mixed and subjected to a contact reaction. The method is characterized in that the catalyst is a soluble zinc salt modified heteroatom molecular sieve.

The invention pertains to the technical field of chemical pharmaceutical production and particularly provides a novel preparation method of sofalcone which has a general formula (I) structure and is mainly applied to the treatment of gastric ulcer and chronic gastritis. The preparation method adopts 2-hydroxy-4-(3-methyl-2-butene oxygen) hypnone as a starting material and a target compound sofalcone (I) is finally prepared after reactions with four steps. Compared with synthesis technologies provided by the existing literatures, the method simplifies the processing method of intermediate products, improves the quality and yield of products and reduces costs.

The invention discloses a synthesis method of 2-phenyl-2-propanol and acetophenone through catalytic oxidation of cumene, the synthesis method includes that firstly, adding the cumene and a solid catalyst into a reactor, forming a suspension through ultrasonic processing, wherein the solid catalyst is nitrogen-doped carbon material, heating the obtained suspension to 40-100 DEG C, introducing oxygen for reaction at constant pressure; after the reaction is finished, separating the reaction mixture to obtain the solid catalyst and a liquid mixture which contains the 2-phenyl-2-propanol, the acetophenone and cumene hydrogen peroxide; and obtaining target products of the 2-phenyl-2-propanol and the acetophenone through separation and purification. The cumene is oxidized at the constant pressure to generate 2-phenyl-2-propanol and acetophenone, the nitrogen-doped carbon material is used as the heterogeneous reaction catalyst, the oxygen is used as oxidant, an operational process is simple, the nonmetal catalyst is free of corrosion, environment-friendly, low in price and capable of being used repeatedly, the conversion ratio of the cumene is relatively high, and the target products are good in selectivity.

The invention relates to a Si-containing macromolecular photoinitiator and the synthesizing method and the uses belong to the photographic polymer material field. In a general formula of the photoinitiator being (I), I is the photoinitiator with hydroxyl, i.e. the hydroxyl-containing benzoin class, benzoin ethers, alkyl-acetophenones, alkyla-acetophenones, benzophenone type, thioxcanthone derivatives, coumarone class and camphorquinone compound; R1 is the alkyl of C1-C12, or the alkyl or aryl of C1-C12 substituted by N, O, S heteroatoms; R2 and R3 are alkyls of C1-C12, the alkyls of C1-C12 substituted by N, O, S heteroatoms, or alkoxyls of C1-C12; n is equal to 3 to 50. The synthesizing method obtains the compounds of isocyanate with photoinitiator by the reaction of the hydroxyl-containing micro-molecular photoinitiator with an isocyanate group of the diisocyanate, and allows the reaction of the photoinitiator-containing compounds of isocyanate with the hydroxyl-containing siloxane macromolecular compounds. The synthesizing method is used for initiating the free radical photopolymerization, improving the speed and efficiency of producing active species by photo sensitive decomposition and reducing the micro-molecular residue and biological toxicity of coatings.

The present invention relates to alpha-phenyl ethyl alcohol synthesizing process, and is especially one in-situ acetophenone hydrogenating process of synthesizing alpha-phenyl ethyl alcohol. Inside the mixed solution of C1-C4 fatty alcohol and water and under the action of Raney nickel catalyst, acetophenone is one-step reacted at 50-300 deg.c and 0.1-10.0 MPa to obtain alpha-phenyl ethyl alcohol. The weight ratio of acetophenone, C1-C4 fatty alcohol and water is 1 to 2.5-60 to 10-160. The present invention has the beneficial effects of no need of outer hydrogen supply, simple technological process, low production cost, use of non-noble metal Raney nickel catalyst, high acetophenone converting rate, high alpha-phenyl ethyl alcohol selectivity up to 90 %, less side products and capacity of separating high purity alpha-phenyl ethyl alcohol.

The invention provides a pyrrole di-methine fluorescent dye and a synthesis method and application; the synthesis method is as follows: a. preparing 2-phenylaziridine from styrene; b. adding 2-phenylaziridine into acetophenone, and reacting to produce 2, 4-diphenylpyrrole in the presence of sodium hydride under room temperature; c. adding 2, 4-diphenylpyrrole into p-hydroxybenzaldehyde, then adding chloranil according to the weight proportion 2, 4-diphenylpyrrole : chloranil =1:3-7; reacting under room temperature with stirring, removing excessive chloranil after reaction, and spinning dry to get blue solid pyrromethene; d. adding blue solid pyrromethene into dichloromethane for dissolution, then adding boron trifluoride diethyl etherate under the protection of inert gas, and reacting under room temperature; after reaction, adding chloroform and extracting 2 to 3 times; combining extract liquids, water washing, drying by anhydrous magnesium sulfate, spinning dry, and column separation to yield products.

The invention discloses an acidizing corrosion inhibitor and a preparation method, the acidizing corrosion inhibitor comprises the following raw materials by weight: 39-41 parts of acetophenone, 24-26 parts of formaldehyde, 9-11 parts of ethene diamine, 24-25 parts of absolute ethyl alcohol, 1-2 parts of concentrated hydrochloric acid, and 1-3 parts of propiolic alcohol. The acidifying corrosion inhibitor employs acetophenone, formaldehyde, absolute ethyl alcohol, concentrated hydrochloric acid, ethene diamine and propiolic alcohol as raw materials, through reasonable complex formulation, the acidifying corrosion inhibitor has good dispersibility in an acid solution, any synergist and surfactant is not required for realizing good compatibility of the acid solution and other acidifying additives; rust inhibition performance is good, the first grade standard in an industry can be reached, no damage is generated to rock core during an acidifying process; influence of the acidizing corrosion inhibitor is little to human body and environment, so that acidifying construction cost is reduced, on-site construction security is increased, the corrosion inhibitor has good economic benefit and environment benefit, and is suitable for popularization and application.

The invention discloses an anti-aging composition with various hyaluronates, which comprises, by weight, 1-10% of butylene glycol, 1-5% of hydrolyzed hyaluronic acid, 1-5% of sodium acetylated hyaluronate, 0.1-5% of sodium hyaluronate, 0.1-5% of a sodium hyaluronate crosslinked polymer, 0.1-5% of hydroxypropyl trimethyl ammonium chloride hyaluronic acid, 0.1-1% of oligopeptide-1, 0.01-1% of blackend swallowwort root extract, 0.1-0.5% of PEG-60 hydrogenated castor oil, 0.1-0.5% of p-hydroxyacetophenone, 0.1-1% of octanohydroxamic acid, and the balance of deionized water, adding up to 100%. Theanti-aging composition has extended functions, provides both moisturizing and skin repairing and soothing; since the anti-aging composition is water soluble, the anti-aging composition is not limitedto product forms and is addable to liquids, milks, creams, essences and the like.

An object of the present invention is to provide an epoxy resin composition that provides, when used for an insulation layer of a multilayer printed wiring board, a multilayer printed wiring board which is excellent in plating adhesion, heat resistance and moisture resistance reliability and capable of forming fine wiring. Another object of the present invention is to provide a resin sheet, a prepreg, a method for producing a multilayer printed wiring board, a multilayer printed wiring board and a semiconductor device.

These objects are achieved by an epoxy resin composition comprising (A) an epoxy resin, (B) a phenoxy resin having a specific bisphenol acetophenone structure and (C) a curing agent, wherein the content of the phenoxy resin (B) is 10 to 30% by weight of the total solid content of the resin composition.