2 results about "Atorvastatin calcium" patented technology

[Problem] To provide an atorvastatin calcium anhydride crystal having higher solubility than that of a conventional hydrate crystal and being more stable than an amorphous form. [Solution] The present invention pertains to an atorvastatin calcium anhydride crystal that exhibits an X-ray diffraction pattern, which has peaks at 2θ = 8.7°, 10.4°, 18.1°, 19.5°, 20.9°, 22.5°, 24.1°, and 25.6°, by X-ray powder diffraction measurement (XRPD) using CuKα radiation.

The application discloses amlodipine atorvastatin calcium tablet and a preparation method and application thereof, relates to the technical field of pharmaceutical preparations, and improves the dissolution rate of benzenesulfonic acid amlodipine and atorvastatin calcium by improving the component formula and micronization treatment of raw materials, and regulates the dissolution rate of benzenesulfonic acid amlodipine and atorvastatin calcium, so that the blood drug concentration is stably in an effective treatment range, thereby improving the bioavailability, reducing the frequency of taking medicine, enhancing the curative effect, and improving the medication compliance.