528 results about "Test solution" patented technology

This invention provides a testing device and method for corrosion and wear testing of sliding guide rails under corrosive environments. The device includes a support module, a drive module, a guide rail, a test slider, a tension sensor, a pull rod, and a test tank module. The test slider is slidably mounted on the guide rail and contains a counterweight to simulate a load. The drive module drives the pull rod to slide along the length of the guide rail. The tension sensor is connected between the pull rod and the test slider. The test tank module holds the test solution to simulate a corrosive environment. This invention features a compact overall structure, simple component installation, and a simple slider force transmission method. It can realistically simulate the corrosion and wear phenomena of the sliding guide rail moving pair under seawater conditions. Furthermore, the adjustable counterweight and replaceable test solution enable this invention to conduct corrosion and wear tests on moving pairs under different load conditions and corrosive environments.

The invention provides a traditional Chinese medicine formula granule spectrum similarity evaluation system, and relates to the technical field of traditional Chinese medicine, and the system comprises: a spectrum acquisition module, which is used for separating active components with similar polarity in a compound salvia miltiorrhiza formula granule test solution by gradient elution based on chromatographic conditions to obtain a characteristic spectrum; and the analysis processing module is used for carrying out analysis processing on overlapped chromatographic peaks in the characteristic spectrum, distinguishing characteristic signals corresponding to main active components and trace components, and realizing separation and identification of characteristic peaks of different components in the mixture so as to obtain a characteristic peak analysis result. According to the method, the standard characteristic chromatogram database is constructed through gradient elution and deconvolution processing, and the accuracy and standardization of quality evaluation of the traditional Chinese medicine formula granules are improved.

The invention relates to the technical field of environmental monitoring, in particular to a method for determining two organophosphate compounds in water. The two organic phosphate ester compounds are tri-(2, 3-dibromopropyl)-phosphate ester and xylenol phosphate ester; the method comprises the following steps: 1, putting a water sample to be detected into a centrifugal tube, adding sodium chloride, uniformly mixing, adding acetonitrile as an extracting agent, uniformly mixing by vortex, standing for layering, and filtering supernatant liquid by a needle filter to obtain liquid to be detected; 2, mixing the prepared tri-(2, 3-dibromopropyl)-phosphate standard intermediate solution with the prepared xylenol phosphate standard intermediate solution, and diluting with acetone to obtain a standard working solution; the to-be-detected liquid obtained in the first step is placed in a liquid chromatography-triple quadrupole mass spectrometry combined system to be analyzed; the method provided by the invention can realize simultaneous determination of tri-(2, 3-dibromopropyl)-phosphate and xylenol phosphate, and fills the blank of combined detection of two specific organophosphate compounds in the prior art.

The invention relates to the technical field of pharmaceutical analysis, in particular to a thin-layer chromatography identification method of vitality-preserving decoction and a preparation thereof. Comprising the following steps: S1, extracting a sample to be detected by using diethyl ether, and preparing a test solution; s2, preparing a cinnamaldehyde reference substance solution and a 6-gingerol reference substance solution; the method further comprises at least one of the steps S3 and S4; s3, dripping the test solution and the cinnamaldehyde reference solution on the same thin-layer plate, developing with a first developing solvent, and identifying the cinnamon; the first developing solvent comprises petroleum ether and ethyl acetate in a volume ratio of (15-20): 3; s4, dripping the test solution and the 6-gingerol reference substance solution on the same thin-layer plate, developing with a second developing solvent, and identifying the ginger; the second developing solvent is prepared from petroleum ether, trichloromethane and ethyl acetate according to the volume ratio of (2-4): (1-2): (1-3). The method is good in overall separation effect, clear in spots, good in specificity and durability, and capable of identifying the medicine flavors of cinnamon and ginger in the vitality-preserving decoction and the preparation thereof.

The invention provides a plastic pipe service life test method and device, and the method comprises the steps: filling a low-level water tank and a circulation test pipeline communicated with the low-level water tank with a test solution, injecting the test solution into a high-level water tank communicated with the low-level water tank, and enabling the interior of the high-level water tank to have a preset test solution initial volume; wherein the high-level water tank is higher than the low-level water tank by a preset height, and a gas phase space is formed at the top of the high-level water tank; charging compressed gas into the gas-phase space to enable the gas-phase space of the high-level water tank to have preset pressure so as to apply back pressure to the test solution in the low-level water tank; under the back pressure condition, heating the test solution in the low-level water tank to a target test temperature; the backpressure condition and the target test temperature are maintained, and the service life of the plastic pipe sample in the circulation test pipeline is tested. Through the integrated structure and process design, the system is in a stable high-temperature and high-pressure test state, the energy utilization efficiency is improved, the operation cost is reduced, and the test efficiency is improved.

This invention discloses a method for dissolving NiCrPSi nickel alloy samples for ICP-OES detection, comprising the following steps: mixing the NiCrPSi nickel alloy sample to be tested with hydrochloric acid aqueous solution, concentrated nitric acid, and hydrofluoric acid aqueous solution, digesting at 120-140℃ for 1.5-2.5h, and then evaporating the solution to dryness at 220-260℃; then adding nitric acid aqueous solution and heating until the solid is completely dissolved, and then diluting with water to obtain the NiCrPSi nickel alloy test solution. The dissolution method of this invention can completely dissolve NiCrPSi nickel alloy powder without elemental loss, providing an accurate sample solution for ICP-OES detection; and it eliminates the need for specialized equipment such as microwave digesters or electrothermal digesters, as well as special reagents such as perchloric acid and tartaric acid, using only conventional acid reagents and general experimental equipment, thus reducing costs, simplifying operation, and enhancing versatility.

The invention discloses a liquid chromatography method for measuring 5-hydroxymethylfurfural in a calcium gluconate and sodium chloride injection. The method comprises the following steps: measuring the calcium gluconate and sodium chloride injection as a test solution; weighing 5-hydroxymethylfurfural, and adding water to dilute the 5-hydroxymethylfurfural to form a reference solution; carrying out continuous sample introduction on the liquid chromatograph by using the reference substance solution to obtain a system applicability solution chromatogram; when the chromatogram of the applicable solution of the system meets the standard, measuring the test solution and the reference solution, respectively injecting the test solution and the reference solution into a liquid chromatograph, and recording the chromatograms; the content of 5-hydroxymethylfurfural in the calcium gluconate and sodium chloride injection is obtained through a 5-hydroxymethylfurfural content calculation formula. The method has the advantages of strong specificity, high sensitivity, good precision, strong durability and the like, and can quantitatively detect 5-hydroxymethylfurfural in the calcium gluconate and sodium chloride injection, so that the safety of clinical medication of the calcium gluconate and sodium chloride injection is improved.

The present application is applicable to the field of medical devices, and discloses a liquid chromatography-mass spectrometry apparatus and a control method for the liquid chromatography-mass spectrometry apparatus. The liquid chromatography-mass spectrometry apparatus comprises a sample storage device, a pretreatment device, a chromatography device, a mass spectrometry detection device, and a controller. The chromatography device comprises a test solution preparation channel, a test solution transfer assembly, a liquid phase fluid delivery assembly, and a chromatography column. An operating pressure outputted by the liquid phase fluid delivery assembly is less than or equal to 20 MPa. The length of the chromatography column is greater than or equal to 3 mm and less than or equal to 35 mm. A sample comprises a target substance to be measured, and the target substance to be measured comprises at least one of vitamin D, a steroid hormone, and a catecholamine. The present application reduces costs of the liquid chromatography-mass spectrometry apparatus.

The invention discloses a method for analyzing and identifying chemical components of Mingzhi astragalus decoction based on high-resolution mass spectrometry, and relates to the technical field of traditional Chinese medicine compound analysis. The method comprises the following steps: preparing a Mingzhi Radix Astragali decoction test solution; the method comprises the following steps: respectively acquiring mass spectrum data in positive and negative ion modes under specific chromatography and mass spectrum conditions by adopting an ultra-high performance liquid chromatography-time-of-flight mass spectrometry technology; and comparing the obtained data with a pre-constructed specific chemical component database of the Mingzhi Astragalus decoction, and realizing systematic identification of the chemical components in the compound and medicinal material attribution according to a principle that an accurate mass number error is in a range of + / -3 ppm. The method provided by the invention efficiently, accurately and successfully identifies 53 chemical components in the Mingzhi radix astragali decoction and clarifies the source medicinal materials of the 53 chemical components, and provides a reliable technical scheme for comprehensively illuminating the basis of the compound substance, quality control and subsequent research.

The invention belongs to the technical field of medicine detection, and particularly relates to an ICPMS (Inductively Coupled Plasma Mass Spectrometry) detection method for element impurities in theophylline. The linear test solution, the blank solution and the theophylline test solution are subjected to ICPMS detection, the content of element impurities in the theophylline test solution is calculated according to an internal standard curve method, and the element impurities are one or more of cadmium, lead, arsenic, mercury, cobalt, vanadium, nickel, lithium, antimony or copper. The method is good in reproducibility and stability, high in accuracy and high in precision.

This invention relates to a method for establishing and detecting the fingerprint spectrum of the traditional Chinese medicine composition Taohongyin. The raw materials of the traditional Chinese medicine composition include: chicken gizzard lining, papaya, hawthorn, chrysanthemum, tangerine peel, peach kernel, and wolfberry. The fingerprint spectrum establishment method includes the preparation of a reference solution and a test solution; detection of the reference solution and the test solution using high-performance liquid chromatography (HPLC); the mobile phase used in the HPLC is acetonitrile and phosphoric acid aqueous solution, and the elution method is gradient elution.

A hydrogen storage alloy-based all-solid-state pH sensor is disclosed, comprising a counter electrode, a working electrode, a reference electrode, and a flexible substrate. The counter electrode is a platinum electrode, the working electrode is a hydrogen storage alloy electrode, the reference electrode is a silver / silver chloride electrode, and the flexible substrate is PET. Using the hydrogen-storage titanium-iron alloy electrode as the working electrode and an Ag|AgCl electrode as the reference electrode, the potential of the test solution is measured, and the pH value of the test solution is obtained through a standard curve. This invention explored the optimal ratio of titanium and iron elements through a series of experiments, enabling the sensor to simultaneously achieve both accuracy and stability. While ensuring good hydrogen ion response, optimal stability is obtained by adjusting the titanium-iron element ratio, making it suitable for long-term real-time online in vivo pH detection.

The present application provides a detection method and quality control method for related substances in dextromethorphan oral solution, which comprises the following steps: dissolving dextromethorphan oral solution in a solvent to obtain a test solution; and performing high performance liquid chromatography detection on the test solution; the mobile phase used in the high performance liquid chromatography detection comprises mobile phase A and mobile phase B, the mobile phase A comprises a phosphate solution, the mobile phase B comprises acetonitrile, and the concentration of the phosphate solution is 0.1 mM-10 mM. The detection method has good linear relationship between dextromethorphan and related substances, good accuracy and sensitivity, strong specificity, high stability, good separation degree and good reproducibility, and is suitable for wide application.

The invention discloses a headspace gas chromatography method for detecting ethanol residual quantity in gastrodin. The headspace gas chromatography method comprises the following steps: (1) preparing a test solution; preparing a reference solution; (3) performing chromatographic determination; and (4) calculating a result. According to the headspace gas chromatography method for detecting the residual amount of ethanol in gastrodin, the headspace equilibrium temperature and time are optimized, a chromatographic column with specific polarity and programmed heating conditions are adopted, the ethanol residue detection method special for a gastrodin matrix is established, matrix interference is effectively overcome, and the detection accuracy is high. The method has high sensitivity and high accuracy, realizes exclusive, accurate and reliable quantitative control of ethanol residues in gastrodin, and has strong practicability.

The application provides an automatic titration analysis method for measuring the aluminum content in high aluminum alloy, which adopts direct reaction of fluoride with a test solution to realize one-step direct titration, and determines the aluminum content in the range of 2.00% to 100.00%, and comprises the following steps: sample decomposition; precipitation of interfering ions; calibration of sodium fluoride standard solution; calibration of automatic potentiometric titrator; and measurement of the sample to be tested. The application solves the problems of sample pretreatment and how to avoid the influence of interfering ions on the determination of aluminum content. The titration operation, reading and calculation are automatically completed by the instrument, effectively reducing human errors, and the application has the advantages of simple operation, accurate and rapid results, wide application range and the like.

This invention provides a method for the simultaneous and rapid detection of four oxidative stress-related biomarkers and its application. The detection method includes: (S1) pretreatment of samples using a protein precipitation extract to simultaneously extract four target compounds: 8-hydroxydeoxyguanosine, 8-isoprostaglandin F2β, 8-isoprostaglandin F2α, and acetyllysine, and preparing a test solution; the protein precipitation extract is a methanol-acetonitrile-perchloric acid mixed solution containing formic acid, wherein the volume ratio of methanol, acetonitrile, and perchloric acid is (8-10):(8-10):(0.5-1), and the volume concentration of formic acid is 0.1-0.5%; (S2) detection of the test solution and standard solution using liquid chromatography-tandem mass spectrometry, and matrix calibration using an internal standard method; plotting a standard curve with the peak area ratio of the target compound to the internal standard as the ordinate and the concentration as the abscissa; and calculating the concentration of the target compound in the test solution based on the standard curve.

The invention relates to a method for measuring and analyzing nickel, silicon and phosphorus in nickel-containing pig iron, in particular to the technical field of detection and analys.The measuring and analyzing method comprises the steps that a nickel-containing pig iron sample is drilled, sampled and separated through a hard alloy drill bit, and a test sample is obtained; sequentially carrying out acid dissolution, solid-liquid separation and constant volume on the obtained test sample to obtain a test solution; measuring the contents of nickel, silicon and phosphorus in the obtained test solution by adopting a full-spectrum direct-reading inductively coupled plasma emission spectrum; a standard curve used in the full-spectrum direct-reading inductively coupled plasma emission spectrum measurement is obtained by dissolving a gradient nickel-containing pig iron standard sample to a constant volume. According to the determination and analysis method provided by the invention, the detection process is designed, so that the nickel, silicon and phosphorus elements in the nickel-containing pig iron with the nickel content of 8-15% can be jointly determined, and a scientific data basis is provided for production management and control.

The invention belongs to the technical field of analysis and detection, and particularly relates to a method for detecting 2-hydroxynaringenin in plants. The detection method comprises the following steps: extracting a plant sample to obtain a liquid to be detected; detecting the liquid to be detected by adopting high performance liquid chromatography-tandem mass spectrometry to obtain the peak area of the 2-hydroxynaringenin in the plant sample; and according to the peak area of the 2-hydroxynaringenin and a preset standard curve, calculating the content of the 2-hydroxynaringenin in the plant sample, the detection conditions of the ultra-high performance liquid chromatography are as follows: a mobile phase A is water; the mobile phase B is acetonitrile; the ion source temperature of the ultra-high performance liquid chromatography is 500 DEG C. The method has the advantages of favorable linear relationship (favorable linear relationship (r gt; 0.999)), favorable precision and favorable repeatability, and can accurately determine the content of 2-hydroxynaringenin in plants.

The invention discloses an image measurement nozzle spraying performance test device, which comprises a test bed, a nozzle, a test solution circulation system, a liquid pump test system and a liquid collection system, and is characterized in that the liquid collection system comprises a plurality of measuring cylinders arranged in a rectangular array, the lower ends of the measuring cylinders are connected with supporting rings, and the lower parts of the supporting rings are fixedly connected with weighing sensors; a water baffle capable of moving up and down is arranged in the measuring cylinder, and a water diversion seat is arranged at the lower end of the water baffle; a plurality of water retaining pieces are connected to the water diversion base, and the upper ends of the water retaining pieces penetrate through the side wall of the water baffle and extend to the upper portion; the output end of the water diversion base is fixedly connected with a conveying pipe. In the using process of the device, a water source in the measuring cylinder can be rapidly discharged, meanwhile, the situation that the water source cannot be completely discharged is avoided, the measuring efficiency is further improved, the using requirements of users are met, and the practicability of the device is indirectly improved.

The invention discloses a quality detection method of tin powder, and belongs to the technical field of quality control of traditional Chinese medicine preparations. The method comprises the following steps: step 1, preparing an indigo reference substance solution; step 2, preparing a test solution; 3, respectively injecting the reference substance solution and the test solution into a high performance liquid chromatograph to obtain chromatograms; and step 4, calculating the content of indigo in the test sample according to the chromatogram, taking the test sample as a qualified product with the content of indigo in each gram of the test sample being not less than 10 mg, and the indigo is calculated by indigo. The method can be used for objectively, comprehensively and accurately evaluating the quality of the tin powder, and has important significance on ensuring the quality of the product while ensuring the curative effect of the product.

The invention relates to the technical field of pharmaceutical analysis, in particular to a chromatographic method for determining optical isomers in a carbidopa raw material medicine and a preparation thereof by using an HPLC (High Performance Liquid Chromatography) method. The detection method is simple, convenient, rapid and accurate to operate, and specifically comprises the following steps: dissolving a proper amount of a sample with a solvent, diluting to a certain concentration, taking a certain volume of the sample, carrying out isocratic elution at a certain column temperature by adopting a high performance liquid chromatography, using a hand-type chromatographic column, a mobile phase A and a mobile phase B, and carrying out quantitative analysis by adopting a self-control method with correction factors. And calculating the isomer in the test solution. The method is good in specificity, solution stability, linearity, repeatability, intermediate precision and durability, and the detection result is accurate and reliable through verification.

The application discloses a kind of compound Xianghua granules fingerprint's construction method, comprising the following steps: preparation of reference solution: p-coumaric acid, ferulic acid standard in methanol is dissolved;Preparation of test solution: different batches of compound Xianghua granules are dissolved in ultrapure water respectively, and post-processing is carried out;Respectively inject high performance liquid chromatography and detect, obtain the fingerprint of reference solution and the fingerprint of each batch sample;Using traditional Chinese medicine fingerprint similarity evaluation system analyzes the fingerprint of each batch sample, generates the control fingerprint of compound Xianghua granules.The method provided by the application can better reflect the multiple index component information of compound Xianghua granules.The fingerprint characteristic peak baseline of the application is smooth, and the sensitivity and separation degree are better, while the operation is quick and reliable, the cost is lower, can effectively, stably and quickly comprehensively monitor product quality, ensure the stability and quality controllability of product.

This invention relates to the field of detection technology and provides a liquid chromatograph for product analysis. The open-top box has a shock-absorbing support at its bottom, on which the liquid chromatograph body is mounted. An exhaust pipe is connected to the liquid chromatograph body, with one end extending outside the open-top box and connected to a condensing mechanism. The condensing mechanism is connected to the open-top box. A cylindrical body is connected to one side of the open-top box via a second fixing plate, and a housing is fixedly connected to one side of the cylindrical body. The bottom of the housing is connected to the cylindrical body via a connecting pipe, and a filtration mechanism is connected to the housing. The bottom of the cylindrical body is connected to the liquid inlet of the liquid chromatograph body via a flexible hose. This invention filters out debris from the extract using several filter screens. The filtered extract is then introduced into the cylindrical body through the connecting pipe and passes through several filter screens to filter out debris from the test solution, preventing debris from clogging the internal pipes of the liquid chromatograph body.

This invention provides a method for detecting dichloronaphthalene, a persistent organic pollutant in soil sediments. The method includes: collecting soil sediment samples, pre-treating them by freeze-drying, grinding, and sieving to obtain a sample; extracting and purifying the sample using an organic solvent to prepare a test solution; analyzing and detecting the sample using ultra-high performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry (UPLC-APCI-MS / MS), and calculating the measured value of dichloronaphthalene in the test solution by substituting the obtained peak area and fractionation ratio into a specific formula. This invention fills the gap in my country's technology for detecting dichloronaphthalene-type persistent organic pollutants in soil sediments. This method can effectively eliminate interference from complex matrices, accurately determine trace amounts of six dichloronaphthalene isomers, and has the advantages of high sensitivity, strong anti-interference ability, simple operation, and high detection accuracy.

A method for improving the accuracy of pH value detection using an antimony-based pH electrode, belonging to the field of pH value detection technology, includes: measuring the dissolved oxygen concentration of the test solution; comparing this dissolved oxygen concentration with the dissolved oxygen concentration of the standard buffer solution used during pH sensor calibration; when the two dissolved oxygen concentrations differ, dissolved oxygen potential compensation is required: multiplying the difference between the two dissolved oxygen concentrations by a dissolved oxygen concentration compensation coefficient to obtain a dissolved oxygen potential compensation value; and using this dissolved oxygen potential compensation value to compensate the electrode potential of the antimony-based pH electrode in the test solution, thereby achieving accurate pH value measurement. This invention improves the measurement accuracy of the antimony-based pH electrode and the accuracy of in-situ pH value monitoring results through dissolved oxygen potential compensation.

The application discloses a kind of 10 kinds of antioxidants in medical device leachable determination method.The present application, by ultra-high performance liquid chromatography time-of-flight mass spectrometry technology realizes the simultaneous determination of ten kinds of antioxidants in medical device leachable, covers different types of antioxidants such as phenolic and phosphite.The pretreatment process only needs to extract the measured product, and the extracted liquid is blown dry by nitrogen, methanol is added, vortexed and filtered through microporous filter to complete the preparation of test solution, and the operation steps are simple, without complex derivatization or purification process, greatly reducing the difficulty and time cost of sample processing.In the analysis process, the ultra-high performance liquid chromatography system is used in conjunction with specific chromatographic column and mobile phase gradient elution program, which can quickly realize the baseline separation of ten kinds of antioxidants, combined with the high sensitivity detection of time-of-flight mass spectrometry, significantly improves the analysis efficiency, and is suitable for rapid screening and quantitative analysis of large quantities of samples.

A method for determining the presence of chromium-6 (Cr-6) in a solid sample is described, comprising the steps of contacting the solid sample with a destruction liquid under conditions in which the Cr-6 of the solid sample dissolves in the destruction liquid as a chromate, providing a test solution; subjecting the test solution obtained in step (1) to a specific Cr-6 detection reaction, under conditions in which the presence of Cr-6 is detected; and detecting whether the specific Cr-6 reaction occurred in step (2); wherein the destruction liquid comprises an oxidant, which has a standard electrode potential E0 higher than the chromate.

A method for measuring the content of hydrazine in a carbidopa-containing drug, comprising the following steps: (1) in a solvent, under the action of acid, mixing a sample under test with an aldehydes substance, said sample being a carbidopa-containing drug, and hydrazine in said sample and the aldehydes substance being derivatized to obtain a test solution; and (2) measuring the content of the hydrazine in the test solution. Compared with the prior art, the method for measuring the content of hydrazine in a carbidopa-containing drug does not require pretreatment to remove carbidopa, introduces negligible hydrazine during measurement, is easy to operate, does not need to accurately control derivatization time and sample introduction time, and exhibits good repeatability and accurate measurements.

The invention relates to a method for determining the content of nitrosamine impurities in a pramipexole dihydrochloride sustained-release tablet, which comprises the following steps: grinding the pramipexole dihydrochloride sustained-release tablet into fine powder as a sample to be detected, and extracting with a diluent to obtain a test solution; and carrying out liquid chromatography-mass spectrometry detection on the test solution, and calculating according to the detection result to obtain the content of the nitrosamine impurity N-nitroso-pramipexole in the pramipexole dihydrochloride sustained release tablet. According to the method, the nitrosamine impurity N-nitroso-pramipexole can be effectively extracted from the pramipexole dihydrochloride sustained release tablet, and the nitrosamine impurity is quantitatively detected by liquid chromatography-mass spectrometry, so that the problems that the nitrosamine impurity N-nitroso-pramipexole is low in content, difficult to detect and easy to interfere are successfully solved. The method is high in accuracy, precision and sensitivity and good in linearity, specificity and system adaptability.

This invention discloses a method for determining the content of target components in Qingning Powder. Stir-fried Lepidium apetalum seeds, stir-fried Plantago asiatica seeds, and stir-fried Glycyrrhiza uralensis are dissolved in methanol solution, shaken well, filtered, and the filtrate is used to obtain a test solution for detection by high-performance liquid chromatography (HPLC). The three target components in the test solution are identified as: quercetin-3-O-β-D-glucose-7-O-β-D-gentiopicroside (C...). 33 H 40 O 22 ), genipinic acid (C 16 H 22 O 10 ), glycyrrhizin (C 21 H 22 The content of O9); the detection method using high performance liquid chromatography includes the following steps; Step 1: Take appropriate amounts of reference standards for quercetin-3-O-β-D-glucose-7-O-β-D-gentiopicroside, genipin glycoside, verbascoside, and glycyrrhizin, respectively, and weigh them accurately. This method for determining the content of target components in Qingning Powder, through monomer analysis combined with specific reference standards, breaks through the mixed bottleneck of the whole formula fingerprint spectrum and quickly locates the responsible medicinal materials of abnormal batches.