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286 results about "Carrier solution" patented technology

Composition for a Tissue Repair Implant and Methods of Making the Same

The invention is directed to a process for making a tissue repair implant having a porous sponge-like structure to repair bone, cartilage, or soft tissue defects by producing a connective tissue homogenate from one or more connective tissues; mixing the connective tissue homogenate with a carrier solution to produce a connective tissue carrier; optionally mixing one or more natural or synthetic bone fragements with said connective tissue carrier to produce a tissue repair mixture; freezing or freeze-drying the tissue repair mixture to produce a porous sponge-like structure and create a three-dimensional framework to entrap the natural or synthetic bone fragments, treating the frozen or freeze-dried porous sponge-like structure with one or more treatment solutions to produce a stabilized porous sponge-like structure. A crudely fragmented connective tissue from one or more connective tissues is optionally mixed with the tissue repair mixture before freezing or freeze-drying. The tissue repair implant having a porous sponge-like structure is optionally combined with one or more bioactive supplements or one or more agents that have bioactive supplement binding site(s) to increase the affinity of growth factors, differentiation factor, cytokines, or anti-inflammatory agents to the tissue repair implant. The invention is further directed toward applying such tissue repair implant for tissue repair.
Owner:LIFENET HEALTH

Antibacterial medical catheter and preparation method thereof

The invention relates to an antibacterial medical catheter. The antibacterial medical catheter comprises a catheter body; an antibacterial coating is coated on inner and outer surfaces of the catheter body respectively and comprises an antibacterial agent and high polymer used as an antibacterial agent carrier, wherein the antibacterial agent accounts for 0.05 to 10 percent based on the total mass of the antibacterial coating. The invention also provides a preparation method for the antibacterial medical catheter. The method comprises the following steps of: treating the surface of a medical catheter; preparing a carrier solution; preparing an antibacterial solution, namely adding the antibacterial agent into the carrier solution, and stirring until a mixture is dispersed uniformly to obtain the antibacterial solution; forming a film, namely immersing the medical catheter of which the surface is treated in the antibacterial solution, and then lifting the medical catheter slowly to ensure that the antibacterial solution naturally flows along the surface of the medical catheter to form the uniform and smooth antibacterial coating; and drying. The antibacterial coating containing antibacterial components is deposited on the surface of the medical catheter and can effectively inhibit the growth of bacteria and exert the good antibacterial capacity for a long time.
Owner:RESEARCH INSTITUTE OF TSINGHUA UNIVERSITY IN SHENZHEN

Method and apparatus for the detection of noncovalent interactions by mass spectrometry-based diffusion measurements

The present invention provides a method and apparatus for detecting the noncovalent binding of a potential ligand (such as a drug candidate) to a target, e.g. a biochemical macromolecule such as a protein. The method is based on the Taylor dispersion of an initially sharp boundary between a carrier solution, and an analyte solution that contains the potential ligand(s) and the target. Dispersion profiles of one or more potential ligands are monitored by mass spectrometry at the exit of the laminar flow tube. Potential ligands will usually be relatively small molecules that have large diffusion coefficients. In the absence of any noncovalent interactions in solution, very steep dispersion profiles are expected for these potential ligands. However, a ligand that binds to a large target in solution, will show an apparent diffusion coefficient that is significantly reduced, thus resulting in a more extended dispersion profile. Noncovalent binding can therefore be detected by monitoring dispersion profiles of potential ligands in the presence and in the absence of the target. In contrast to other mass spectrometry-based methods for detecting noncovalent interactions, this method does not rely on the preservation of specific noncovalent interactions in the gas phase. This method has an excellent sensitivity and selectivity, therefore it can be used for testing multiple potential ligands simultaneously. The method is therefore useful for the high throughput screening of compound libraries.
Owner:UNIV OF WESTERN ONTARIO

Test method of micro amount of arsenic or antimony in steel

The invention relates to a test method of steel, in particular to a test method of a micro amount of arsenic or antimony in steel. The test method is based on a principle of a flow injection-hydride generation-atomic absorption spectroscopic methodology, and experiments are determined in a flow-injection sample-injection mode. The method comprises the following steps: a test solution is reduced bya thiourea-ascorbic acid mixed solution and a hydrochloric acid solution to convert arsenic (V) into arsenic (III), and convert antimony (V) into antimony (III); the test solution reacts with a potassium borohydride solution under a carrier band of a carrier solution to generate a great amount of nascent oxygen which reacts with the arsenic (III) or the antimony (III) to generate gaseous AsH3 orSbH3; the AsH3 or the SbH3 is led into a specially-designed quartz tube by high-purity argon gas as carrier gas and is atomized into ground-state atomic vapor; ground-state electrons which are on theoutermost layer of the atom are excited by the light energy of a light source of a hollow cathode lamp to transit to a high energy level; and the amount of abortion light intensity is directly proportional to the concentration of the atom. Accordingly, the arsenic or antimony content in the test solution can be quantitatively analyzed.
Owner:CHINA YITUO GROUP

Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like

Systems and methods for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and treating hyperglycemia, Alzheimer's disease, sleep disorders, Parkinson's disease, Attention Deficit Disorder and nicotine addiction involve synchronizing and tailoring the administration of nutraceuticals, medications and other substances (for example, stimulants) in accordance with the body's natural circadian rhythms, meal times and other factors. Improved control of blood glucose levels, extended alertness, and weight control, and counteracting of disease symptoms when they are at their worst are possible. An automated, pre-programmable transdermal administration system is used to provide pulsed doses of medications, pharmaceuticals, hormones, neuropeptides, anorexigens, pro-drugs, stimulants, plant extracts, botanicals, nutraceuticals, cosmeceuticals, phytochemicals, phytonutrients, enzymes, antioxidants, essential oils, fatty acids, minerals, vitamins, amino acids, coenzymes, or other physiological active ingredient or precursor. The system can utilize a pump, pressurized reservoir, a system for removing depleted carrier solution, or other modulated dispensing actuator, in conjunction with porous membranes or micro-fabricated structures.
Owner:MORNINGSIDE VENTURE INVESTMENTS

Insulin carrier transdermal drug delivery preparation and preparation method thereof

The invention discloses an insulin carrier transdermal drug delivery preparation which comprises the following components of insulin, phospholipid, cholesterol, surfactant, transdermal penetration enhancer, triethanolamine-hydrochloric acid and gel. A preparation method of the insulin carrier transdermal drug delivery preparation comprises the steps of: 1, taking the phospholipid, the cholesterol, the surfactant and the transdermal penetration enhancer and then adding into alcohol for dissolving; 2, taking insulin, dissolving the insulin with a triethanolamine-hydrochloric acid buffer solution, adding the obtained solution in the solution obtained in the step 1, homogenizing and nanometerizing liquid through micro jet to obtain an insulin carrier solution; and 3, taking the gel, adding water to enable the gel to be swelled to prepare a gel substrate, slowly adding the insulin carrier solution in the step 2 into the gel substrate, and uniformly stirring to obtain the insulin carrier transdermal drug delivery preparation. The insulin carrier transdermal drug delivery preparation prepared by adopting the preparation method disclosed by the invention has the characteristics of uniformparticle size, higher entrapment rate, good stability and convenience for medicine delivery; and at least three days of medicine delivery time can be maintained, and compliance of patients is improved while the medicine delivery interval is greatly shortened.
Owner:ηŽ‹δΉ‰ζ˜Ž

Copper-based methanol synthesis catalyst and preparation method therefor

The invention provides a preparation method for a copper-based methanol synthesis catalyst. The method comprises: (1) separately preparing aqueous solutions of a water soluble salt of copper and a water soluble salt of zinc, and mixing the aqueous solutions to obtain a copper-zinc mixed solution; (2) mixing water soluble carbonate and bicarbonate and preparing an aqueous solution of the mixture to obtain a double precipitator buffer liquid; (3) adding the copper-zinc mixed solution into the double precipitator buffer liquid during stirring, and stirring and aging the mixture to obtain a copper-zinc suspension; (4) separately preparing aqueous solutions of a water soluble salt of aluminum and a water soluble salt of transitional metal and/or a rare earth element, and mixing the solutions to obtain a carrier solution; (5) adding ammonia water into the carrier solution during stirring to obtain a carrier suspension; and (6) adding the carrier suspension into the copper-zinc suspension during stirring, and carrying out washing, filtering, drying, roasting and moulding treatment to obtain the copper-based methanol synthesis catalyst. The invention further provides a catalyst prepared by the method and use of the catalyst.
Owner:DATANG INT CHEM TECH RESINST +1

Novel coupling film separating method and device used in gas separation

The invention relates to a method for gas separating, a device thereof and a novel coupled film separation method for gas separating. The material gas is separated through a plurality of separation units, the material gas of each separation unit is firstly contacted with the gas separation film of one side, the gas component forming ligand structure with carrier solution by the form of improving transfer is firstly dissolving and diffusing in the gas separation film contacted therewith, then forms ligand structure with the carrier solution to pass the thin carrier solution and contact with the gas separation film at the other side by the form of improving transfer, and desorbs at the infiltration side by dissolving and diffusing in the gas separation film; the gas component in the material gas which can not form ligand structure with carrier solution is firstly dissolving and diffusing in the gas separation film contacted therewith, then contacts with the gas separation film at the other side by the form of dissolving and diffusing in the thin carrier solution, and desorbs at the infiltration side by dissolving and diffusing in the gas separation film to arrive at the purpose for separating the material gas. The separation method of the invention can satisfy the demand for the gas high pressure separating, avoid plastic effect, prevent wetness and leak of the film, and maintain long-time stability.
Owner:TIANBANG NAT ENG RES CENT OF MEMBRANE TECH
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