45 results about "Carrier solution" patented technology

The invention relates to the technical field of traditional Chinese medicine nano preparations, in particular to traditional Chinese medicine polysaccharide radiotherapy sensitization nanoparticles and a preparation method thereof.The preparation method comprises the following steps that 1, a chitosan-based carrier and traditional Chinese medicine polysaccharide are dissolved in a buffer solution, and the chitosan-based carrier is selected from chitosan, carboxymethyl chitosan or quaternized chitosan; step 2, putting the chitosan-based carrier solution into a reaction container, and dropwise adding glacial acetic acid to adjust the pH value of the system; 3, a cross-linking agent solution is dropwise added at a constant speed, a cross-linking agent is a multivalent anion / cation compound, and stirring is performed to form a core-shell structure; step 4, dropwise adding a traditional Chinese medicine polysaccharide solution into a mixed system in the step 3, and continuously stirring; step 5, filtering and granulating the obtained solution to obtain nanoparticles; according to the traditional Chinese medicine polysaccharide radiotherapy sensitization nanoparticles and the preparation method thereof, not only is radiotherapy sensitization achieved, but also the immunoregulation function is achieved, and the synergistic interaction of radiotherapy and immunotherapy is achieved by activating dendritic cells and T cells.

The invention relates to the technical field of iodide content detection, in particular to a method for determining radiochemical purity and iodine content of sodium iodide capsules for diagnosis by HPLC (High Performance Liquid Chromatography), which comprises the following steps: setting chromatographic conditions, and connecting a radioactive flow detector and an ultraviolet detector in series; preparing a disodium hydrogen phosphate solution, a glucose solution, a vitamin C solution, a first control solution, a potassium iodate solution, a second control solution, a carrier solution, a first sample solution, a second sample solution, a negative control solution and a test solution; and determining the radiochemical purity and iodide content of the first sample solution and the second sample solution in three batches based on the chromatographic conditions and the determination standard. According to the method, test parameters such as capsule sample analysis time, a pretreatment mode and a sample size are optimized, the radiochemical purity of the capsule is accurately determined, and the iodide content is controlled, so that the problem that main components cannot be accurately quantified and potential radioactive impurities cannot be detected by a traditional diagnosis sodium iodide [131I] capsule determination method is solved.

A method for immobilizing beta-glucanase based on a rice husk-sodium alginate composite carrier belongs to the field of enzyme engineering and biological materials, and comprises the following steps: 1) crushing and sieving rice husks; 2) mixing rice husks and sodium alginate according to a mass ratio of 1: 3-1: 6, and performing ultrasonic dispersion and magnetic stirring to form a carrier solution; (3) adding beta-glucanase into the carrier solution, and reacting for 35-50 minutes at the temperature of 30-35 DEG C; and 4) dropwise adding the enzyme-carrier mixed solution into a calcium chloride solution for curing and forming, and washing and drying to obtain the immobilized enzyme particles. By optimizing the ratio of the composite carrier, when the mass ratio of the rice husks to the sodium alginate is 1: 4, the catalytic activity of the prepared immobilized enzyme under unit mass is obviously higher than that of other ratio groups. According to the method, agricultural waste rice hulls are used as main raw materials, the cost is low, the process is simple, the prepared immobilized enzyme is high in activity, and a new way is provided for industrial application of beta-glucanase.

The invention provides a steroid hormone double-bond selective hydrogenation catalyst as well as a preparation process and application thereof, and belongs to the technical field of catalysts. The preparation process of the hydrogenation catalyst comprises the following steps: (1) preparing a carrier loaded with an active metal: dispersing the carrier in a cerium-containing metal salt ethanol solution, stirring, and carrying out suction filtration, drying and temperature programming roasting after stirring to prepare the carrier loaded with the active metal; (2) loading a bimetal carrier: dipping the active metal-loaded carrier in the precursor solution, carrying out ultrasonic-assisted dipping, and then dropwise adding an alkali solution to adjust the pH value of the solution so as to obtain a bimetal-loaded carrier solution; and (3) reduction: slowly dropwise adding a reducing agent solution into the solution, and after reduction is completed, separating, washing and carrying out vacuum drying to obtain the catalyst. The preparation process is green and safe, and the prepared catalyst can be used for selective hydrogenation reaction of steroid hormone double bonds and has relatively high selectivity and conversion rate.

The invention discloses a tellurium-based nano material capable of efficiently inducing copper death as well as a preparation method and application of the tellurium-based nano material. The preparation method comprises the following steps: by taking water as a medium, mixing soluble copper salt and a sulfydryl-containing compound, and stirring to react, so as to obtain a Cu-S2 solution; dropwise adding the Cu-S2 solution into the TeO2 nano-carrier solution, and carrying out stirring reaction; and after the reaction is finished, carrying out solid-liquid separation, taking the solid, and resuspending with methanol to obtain the TeO2 coated Cu-S2 nano material. The preparation method is simple and rapid, large-scale production can be achieved, and the obtained TeO2 coated Cu-S2 nano material can efficiently induce cancer cells to generate copper death, is effective to various cancer cells and has potential clinical transformation application prospects.

To provide a loading body which can realize a high transportation efficiency of a box body.SOLUTION: A loading body, which comprises a pallet comprising a rectangular loading surface and a plurality of box bodies loaded on the loading surface, is a loading body where the bottom surface of a box body faces the loading surface, satisfying a formula (1): y-nx<z (1), (in the formula, n is an integer of 2 or more, x is a length of a side constituting the bottom surface, y is a length of a side constituting the rectangle, z is a length less than x), or a formula (2): mSb<Sp<(m+i)Sb (2), (in the formula, m is an integer of 2 or more, Sb is an area of the bottom surface, Sp is an area of the loading surface, and i is a positive number of 1 or less.)SELECTED DRAWING: Figure 3

A fixing carrier unit for selective wave soldering and a fixing carrier assembled therefrom are disclosed, belonging to the technical field of soldering carriers in the electronics manufacturing industry. The unit includes a wave soldering substrate, an FPCA device mounted on the substrate, a connector inserted into the FPCA device, and a pressure block covering the FPCA device and connector. The pressure block includes a working surface in contact with the FPCA device and connector, and an upper surface opposite to the working surface. A cavity is formed on the working surface, the cavity having a through portion and a sealing portion. The through portion accommodates the protrusion of the connector, and a resilient pin is disposed on the pressure block of the sealing portion. This provides a novel selective wave soldering fixing carrier solution that uses the pressure block to limit the misalignment of the pins and FPC pads.

The invention discloses a process method for preparing DMCD from DMT by using a nickel-based catalyst, and belongs to the technical field of industrial catalysis, and the process method comprises the following steps: S1, preparing the nickel-based catalyst: taking a carbonate solution, a carrier solution and an active metal salt solution as raw materials, mixing and reacting, adding an alkali liquor to adjust the pH to be alkaline until the color of the turbid liquid is changed from blackish green to brown, and filtering to obtain the nickel-based catalyst; standing, centrifugally drying, roasting, and carrying out reduction reaction to obtain the catalyst. S2, filling the fixed bed device with a catalyst; and S3, feeding the dissolved DMT and hydrogen into a fixed bed device according to a certain flow rate, starting a hydrogenation reaction, and continuously producing DMCD. According to the present invention, the DMT is dissolved by using the organic solvent and then is fed on the fixed bed, the continuous production can be achieved by using the fixed bed device, the DMT hydrogenation conversion rate is high, the catalyst can be repeatedly used, the reaction pressure is limited to be low pressure (less than or equal to 1 MPa) in the method, the safety is provided, and the high practical value and the industrial application prospect are provided.

The application discloses a sea fennel composite intelligent microcapsule based on sequential cross-linking, a preparation method and application, and belongs to the technical field of biomedicine.The application provides the sea fennel composite intelligent microcapsule based on sequential cross-linking, aiming at the problems of chemical instability, low transdermal rate, lack of environmental responsiveness of sea fennel extract, and loose capsule wall structure of existing microencapsulation technology, and incapability of precise control.Through integration of high-controllable technologies such as microfluidic layer-by-layer self-assembly, isothermal titration calorimetry monitoring cross-linking and atomic force microscope-nano indentation characterization, three-step sequential cross-linking is adopted to construct the intelligent microcapsule which is uniform in structure, excellent in mechanical performance, has a precise pH response threshold, realizes mild and efficient encapsulation of active substances, actively senses the skin barrier state and precisely controls the release, and synergistically enhances the mechanical strength and processing resistance, thereby providing a carrier solution with high technical barriers for high-end functional cosmetics.

The invention relates to the technical field of organic synthesis, in particular to an immobilization method of a biocatalyst and application of the biocatalyst in synthesis of chiral pesticides. The immobilization method comprises the following steps: uniformly mixing a sodium alginate solution and a sodium carboxymethyl cellulose solution to obtain a carrier solution; dissolving a biocatalyst in a buffer solution to prepare an enzyme solution, and fully mixing the enzyme solution with the carrier solution; dropwise adding the mixed solution into a calcium chloride solution to form gel microspheres; and adding the gel microspheres into an epichlorohydrin solution for crosslinking to obtain the immobilized biocatalyst. According to the preparation method disclosed by the invention, the epoxy chloropropane is added for crosslinking, so that the defects of poor stability, low loading rate and unstable selectivity of a traditional immobilized carrier formed by sodium alginate and sodium carboxymethyl cellulose are overcome, the stability of the immobilized enzyme is improved, the immobilized enzyme is repeatedly used for multiple times, the use cost of an enzyme preparation is greatly reduced, and the preparation method is suitable for industrial production. The method is suitable for application and popularization in production practice.

A delivery system for treating cancer and associated methods thereof. The delivery system includes a needle system comprising a needle with a needle lumen supported by a needle hub, and a plurality of beads containing a radio-therapeutic agent. Additionally, the system includes a syringe system comprising a syringe barrel with a syringe cavity, a plunger, a dilutant vial containing a solvent, and a powder vial containing a solute. The plunger is used to mix the solvent with the solute, forming a carrier solution when urged from a first position to a second position. Further urging of the plunger from the second position to a third position causes the carrier solution to be delivered through the needle, forming a matrix that includes the plurality of beads. The matrix is disposed at a target location, e.g., between a rectal wall and prostate. A second hydrogel is deposited to protect the rectal wall.

The present invention provides an adjustment device for adjusting the distance between two components that is easy to operate, has a simple structure, and can be used reliably, as well as a carrier having the adjustment device. [Solution] An adjustment device comprising: a locking member having a locked position and an unlocked position; a fixed end; an operating end; and an adjustment member having at least two sliding contact portions and at least one locking portion located between the fixed end and the operating end, wherein the sliding contact portions and locking portions are alternately arranged, the sliding contact portions and the locking member are slidably engaged, thereby allowing the locking member to slide against the adjustment member at the sliding contact portions; when the locking member is in the locked position, the locking portions prevent the locking member from sliding against the adjustment member from one side away from the operating end of the locking portion toward the operating end; when the locking member is in the unlocked position, the locking member can slide against the adjustment member from one side away from the operating end of the locking portion toward the operating end.

The present disclosure relates to a method of detecting particles using centrifugal field flow fractionation. The present disclosure provides methods of detecting the size, density, or size and density of lipid nanoparticles. The detection may be performed by centrifugal field flow fractionation using a carrier solution comprising monosaccharides.

Provided is a method to prepare a solid dispersion composition comprising an active pharmaceutical ingredient (API) and a pharmaceutically acceptable dispersion carrier, which includes (a) dissolving the API and the pharmaceutically acceptable dispersion carrier in a solvent to form a dissolved API / pharmaceutically acceptable dispersion carrier solution; and / or (b) combining the dissolved API / pharmaceutically acceptable dispersion carrier solution and an anti-solvent to form a combination, wherein the anti-solvent comprises a surfactant; and / or (c) mixing the combination to generate an emulsion with a predetermined mean particle size range; and / or (d) removing the solvent from the emulsion to generate the solid dispersion composition, wherein the solid dispersion composition has the predetermined mean particle size range. Preferably, the API in the solid dispersion composition is amorphous. Also provided is an emulsion and / or a solid dispersion composition comprising the API and a dispersion carrier. Also provided is a solid dispersion made by the methods of the invention. In embodiments, the present invention includes Compound (1), also known as zongertinib, and apparatus for continuous processing according to the methods disclosed herein.

The invention belongs to the technical field of biological medicine, and particularly discloses fluorouracil sustained-release nano-microspheres as well as a preparation method and application thereof. The preparation method comprises the following steps: S1, dissolving fluorouracil in a polyarginine aqueous solution, uniformly stirring, and adjusting the pH value to 7.2-7.4 to obtain a fluorouracil solution; s2, dissolving amphiphilic alginate in water, sequentially adding carboxymethyl chitosan and quaternized gelatin, and uniformly stirring to obtain a composite carrier solution; and S3, mixing the fluorouracil solution obtained in the step S1 with the composite carrier solution obtained in the step S2, performing ultrasonic treatment, performing self-assembly, performing centrifugation, and collecting precipitates to obtain the fluorouracil nano-microspheres. The invention discloses a fluorouracil sustained-release nano-microsphere as well as a preparation method and application thereof. The fluorouracil sustained-release nano-microsphere can be used for remarkably improving the encapsulation efficiency and the drug loading capacity of fluorouracil, realizing long-acting sustained release of drugs, enhancing the tumor targeting property and the cell uptake efficiency and improving the treatment effect.

This invention belongs to the field of pharmaceutical technology, specifically relating to a method for preparing mabaloxavir tablets and its application. This invention uses lactose dodecyl ester and microcrystalline cellulose to microcrystallize mabaloxavir, reducing its particle size and increasing its specific surface area, thereby accelerating the drug's dissolution rate in vivo, improving its bioavailability, allowing the drug to exert its effects more quickly, and shortening the patient's treatment cycle. The use of lactose dodecyl ester, microcrystalline cellulose, croscarmellose sodium, and povidone K25 as excipients helps form a uniform and stable carrier solution and mixture, and also improves the tablet's formability, disintegration, and dissolution properties during tableting, improving tablet quality and stability, reducing gastrointestinal irritation, and enhancing patient medication adherence.

The invention discloses a preparation method of a platinum-based catalyst for catalytic degradation of short-chain hydrocarbon VOCs (Volatile Organic Compounds), which comprises the following steps: dissolving a cobalt salt precursor and a zirconium salt precursor in a molar ratio of (8-9): 1 in ultrapure water, adding an organic acid solution while stirring, and ensuring that the molar concentration of the organic acid solution is higher than that of a total metal salt solution; stopping stirring after the solution generates a gelatinous substance, raising the temperature to 70-100 DEG C, and drying overnight; grinding the obtained solid material, and roasting in a muffle furnace; after cooling, weighing a certain mass of product, dissolving in a proper amount of ultrapure water, and stirring to obtain a carrier solution; and dropwise adding an active noble metal platinum precursor salt solution into the carrier solution, fully stirring, drying overnight, roasting a sample in the air at 300-400 DEG C for 3-5 hours, cooling, and introducing a mixed gas of hydrogen and nitrogen for reduction. The catalyst prepared by the method is simple in preparation method, has excellent sulfur tolerance, and can catalytically decompose ethane at the temperature of lower than 300 DEG C.

The invention relates to the technical field of bioengineering, and provides a preparation method for synthesizing aminobutyric acid through whole-cell immobilization efficient catalysis. The method comprises the following steps: firstly, adding urea as a nitrogen source in the culture process of corynebacterium glutamicum, and feeding glycerol, sorbitol and biotin complex liquid to culture thalli; then carrying out low-temperature incubation treatment on the thalli by using pyridoxal phosphate, and then carrying out mixed incubation with mercapto-histidine trimethyl inner salt; then preparing an embedding carrier solution by using sodium alginate, polyvinyl alcohol and graphene oxide, and adding glutaraldehyde as a cross-linking agent; mixing the treated thalli with an embedding carrier, and adding a mixture of boric acid and calcium chloride; and finally, dropwise adding the mixed solution into a sodium sulfate solution to form gel particles, and storing the gel particles by using an acetic acid-vitamin C composite buffer solution. The immobilized cells prepared by the method have high mechanical strength, high cell encapsulation rate and high conversion rate, are suitable for long-term preservation, still have activity of 90% or more of the original activity after being refrigerated for 10 days, and still have yield of 360 g / L or more after being used for 10 batches.

The application discloses a kind of polytetrafluoroethylene porous and preparation method thereof.The method comprises the following steps: water-soluble polymer spinning carrier solution, dispersion emulsion, regulator or reinforcing body solution is mixed in certain proportion respectively to obtain porous support layer, middle layer and surface layer spinning solution, then sequentially spin to obtain nascent film, and then solidify in coagulation bath, sintering heat treatment in muffle furnace, cleaning and drying, to obtain multistage porous structure PTFE porous membrane.The application does not use fluorosilane, hydrophobic nanomaterial and other reagents, reduces reagent pollution and recovery, avoids nanoparticle shedding, is integrally formed by sintering process PTFE in-situ mutual adhesion, without layering, high strength, with mutually interpenetrating open structure, good permeability, resistant to high temperature and chemical reagent, with self-supporting, structure controllable, thickness adjustable.

To provide a method for detecting lipid nanoparticles.SOLUTION: The present disclosure provides a method for detecting size, density, or both size and density of lipid nanoparticles. The detection can be performed using centrifugal field flow fractionation with a carrier solution containing monosaccharides.SELECTED DRAWING: Figure 1

Provided is a method to prepare a solid dispersion composition comprising an active pharmaceutical ingredient (API) and a pharmaceutically acceptable dispersion carrier, which includes (a) dissolving the API and the pharmaceutically acceptable dispersion carrier in a solvent to form a dissolved API / pharmaceutically acceptable dispersion carrier solution; and / or (b) combining the dissolved API / pharmaceutically acceptable dispersion carrier solution and an anti-solvent to form a combination, wherein the anti-solvent comprises a surfactant; and / or (c) mixing the combination to generate an emulsion with a predetermined mean particle size range; and / or (d) removing the solvent from the emulsion to generate the solid dispersion composition, wherein the solid dispersion composition has the predetermined mean particle size range. Preferably, the API in the solid dispersion composition is amorphous. Also provided is an emulsion and / or a solid dispersion composition comprising the API and a dispersion carrier. Also provided is a solid dispersion made by the methods of the invention. In embodiments, the present invention includes Compound (1), also known as zongertinib, and apparatus for continuous processing according to the methods disclosed herein.

The invention relates to the technical field of chemical materials, in particular to a preparation method of a high-fluorescence-intensity water-soluble penetrant, which comprises the following steps: S1, synthesizing a fluorescent dye monomer and hydroxyethyl acrylate into a modified fluorescent dye; s2, dissolving methyl phenyl silicone resin in ethyl acetate to generate a carboxyl-containing carrier solution; s3, adding the modified fluorescent dye into the carboxyl-containing carrier solution to generate a fluorescent grafted carrier; s4, adding a permeation activating agent into the fluorescent grafting carrier; s5, adding a fluorine-containing surfactant and a light stabilizer into the pre-polymerized permeation phase, and carrying out high-speed micro-emulsification treatment; s6, adjusting the pH value of the emulsion to 8.0 to 8.5; and S7, filtering the stabilized penetrant crude product. According to the preparation method disclosed by the invention, a preparation scheme of the penetrating agent with high fluorescence intensity, good water solubility and structural stability is realized by constructing a grafting system of the modified fluorescent dye and the carboxylated silicon carrier and combining a multi-component synergistic emulsification and pH regulation process.

The embodiments of the present application relate to the technical field of coating. Disclosed are a coating composition, a coating method for accentuating wood grain, and a coated wood. The coating composition and coating method provided in the present invention provide an effective solution to the problems in the prior art of the presentation of wood grain being unclear, and the coating having an excessively high hiding power and being prone to discoloration. Shellac or a shellac-based derivative material is selected as a film-forming agent, and is formulated with a suitable volatile carrier solution, thereby ensuring that a paint film formed by a coating on a wood surface is transparent and long-lasting, and prolonging the service life of the wood surface. By means of the detailed coating steps, it is ensured that the coating uniformly covers the wood surface and penetrates deep into fine pores of the wood, such that wood grain is more distinct, and wood grain blurring caused by coating accumulation or uneven coating penetration in conventional processes is prevented. In summary, the coating composition and coating method of the present invention achieve an ideal effect of both aesthetics and practicality.

A purification method for detection of a strontium isotope in a silk cultural relic. The method includes: (1) enrichment of the strontium isotope: after cleaning the silk cultural relic, adding the silk cultural relic to a digestion agent for microwave digestion, and conducting evaporation drying; and adding a dried product to a nitric acid solution for centrifugal separation, and extracting a supernatant; and (2) purification of the strontium isotope: first, mixing 4′,4″(5″)-di-tert-butyldicyclohexano-18-crown-6 and a defoamer and adsorbed to a purified resin separation column, and pre-cleaning the purified resin separation column with a nitric acid solution; next, injecting the supernatant in step (1) into the purified resin separation column with a nitric acid solution as a carrier solution; and then, injecting an 84Sr solution and an elution solution into the purified resin separation column in sequence to obtain a separated and purified strontium solution.

The present invention relates to a fatty acid separation adsorbent and a preparation method thereof. The preparation method comprises the following steps: 1) mixing a carrier and a solvent, heating, adjusting the pH, and stirring evenly to obtain a carrier solution; dissolving an aminosilane coupling agent in the solvent, stirring evenly, and adding the mixture to the carrier solution; heating and refluxing, washing, filtering, and drying the mixture to obtain a modified carrier material; 2) dissolving the modified carrier material in dioxane, and then adding an AlCl3 ethanol solution containing carbon disulfide to the mixture, and reacting the mixture to obtain a single metal ion complex material Al2O3. 3+ / modified support material. 3) Take the Al 3+ The modified carrier material reacts with silver halide and is then vacuum dried. This fatty acid separation adsorbent has different adsorption and separation capabilities for saturated fatty acids, monounsaturated fatty acids, and polyunsaturated fatty acids, enabling efficient separation of fatty acids and promising industrial application prospects.

The invention relates to the technical field of special functional materials, in particular to an aerosol self-organizing light scattering shielding material and a preparation method thereof.The aerosol self-organizing light scattering shielding material is prepared from, by weight, 52.0-55.0 parts of rare earth doped hollow microspheres, 12.0-15.0 parts of a thermochromic outer layer, 10.0-12.0 parts of a surface modification and charge stabilization system and 15.0-18.0 parts of an aerogel network, 3.0-3.0 parts of a carrier solution and a stabilizer; through an optimally designed rare earth doped hollow microsphere structure, gt, gt and gt are realized in a visible light wave band (400-700 nanometers); the Mie scattering efficiency is 98%, and an effective optical shielding barrier is formed.

The invention relates to the technical field of biological medicine, in particular to a method for improving the bioavailability of curcumin and a preparation. According to the preparation method, a curcumin solution / carrier solution is prepared under the alkaline condition, the composition of the wall material is optimized, an alkaline core material-composite wall material-homogeneous stabilization-spray drying integrated micro-capsule preparation process is formed, and efficient embedding and stable delivery of curcumin can be achieved; the preparation process is simple, low in energy consumption, low in production cost and suitable for large-scale production and application; the curcumin microcapsule provided by the invention takes a'protein-cyclodextrin-curcumin 'ternary complex as an inner core, takes maltodextrin as a shell layer, is nanoparticles with uniform particle size, has a high Zeta potential absolute value, an embedding rate up to 97-99% and a drug loading rate up to 9-15%, greatly improves the water solubility, palatability, storage stability and bioavailability of curcumin, and is suitable for industrial production. And the application range of curcumin in oral preparations is widened.

To provide a water-soluble saccharide that is capable of supporting various proteins such as enzymes and also capable of forming a carrier with high shape flexibility.SOLUTION: A water-soluble saccharide for a carrier according to the present disclosure is constituted by modifying at least some of hydroxyl groups possessed by the saccharide with (meth)acryloyl groups, the water-soluble saccharide serving for forming a carrier supporting a protein.SELECTED DRAWING: None

The invention discloses a bifidobacterium animalis subsp. Lactis BD108 preparation as well as application and a product of the bifidobacterium animalis subsp. Lactis BD108 preparation in emotion regulation, and belongs to the technical field of microorganisms. The invention aims to solve the technical problems that the survival rate of viable bacteria is low after oral administration, the mood improvement effect is unstable and long-acting intervention is difficult to realize due to the problems of weak strain specificity, insufficient mood regulation activity, poor preparation protection effect, single action pathway and the like existing in the conventional probiotic strain in mood regulation application. According to the key point of the technical scheme, the freeze-dried microsphere preparation of the animal bifidobacterium subsp. Lactis BD108 is provided and comprises the animal bifidobacterium subsp. Lactis BD108 and a composite carrier solution, the preservation number of the animal bifidobacterium subsp. Lactis BD108 is GDMCC (China General Microbiological Culture Collection Center) No.67826; the composite carrier solution is composed of trehalose, pullulan, whey protein phosphopeptides and a solvent.

The invention belongs to the technical field of medicines, and particularly relates to a preparation method and application of a macloxvir tablet. According to the invention, lactose dodecyl ester and microcrystalline cellulose are adopted to carry out microcrystallization on the macarovir, so that the particle size of the macarovir is reduced, the specific surface area of the macarovir is increased, the dissolution speed of a medicine in a body is accelerated, the bioavailability of the medicine is improved, the medicine can play a role more quickly, and the treatment cycle of a patient is shortened. Lactose dodecyl ester, microcrystalline cellulose, croscarmellose sodium, povidone K25 and the like are selected as auxiliary materials to help to form a uniform and stable carrier solution and a mixture, the formability, disintegration, dissolution and other properties of the tablet can be improved in the tabletting process, the quality and stability of the tablet are improved, the irritation of the medicine in gastrointestinal tracts is reduced, and the bioavailability of the medicine is improved. The medication compliance of a patient is enhanced.