The invention relates to a polyhydroxyl hydrolyzed micelle acidolysis blockage removal agent and a blockage removal technology. The polyhydroxyl hydrolyzed micelle acidolysis blockage removal agent is prepared by mixing the following compositions in percentage by mass: 0-30% of alcohol substances, 0-10% of polyethylene glycol, 1-40% of organic solvents, 0-20% of alkyl sulfonate, 0-20% of alkyl sulfobetain, 0-20% of polyoxyethylene ether, 0-20% of sorbitan monstearate, 0-20% of ammonium fluoride, 0-20% of organic acid, 0-20% of organic phosphonic acid, 0.5-2% of acidizing corrosion inhibitor, and the balance of industrial hydrochloric acid, then performing high-temperature high-speed stirring, adding other treating agents and evenly stirring; the blockage removal technology comprises the following steps: performing sand removal, injecting prepad fluid, then sequentially firstly injecting high-concentration polyhydroxyl hydrolyzed micelle acidolysis blockage removal agent solution and low-concentration polyhydroxyl hydrolyzed micelle acidolysis blockage removal agent solution, then injecting displacement fluid, finally injecting water to be filled in an oil pipe, reacting, and restoring the water injection. The blockage removal success rate is high.