332 results about "Vial" patented technology

To provide a method for transporting thermoplastic resin vials under sterile conditions and in an exogenous pyrogen-free state, introducing the vials into a filling assembly line, and thereafter allowing the vials to stand without tipping or dropping them, the method is a method for packing vials for filling with contents such as medicaments or cells by vacuum-packing the vials, and includes the following steps:(I) inserting a plurality of vials in a tray with opening portion sides of the vials facing a bottom of the tray,(II) installing a soft film on bottom portions of the vials,(III) introducing the tray having the vials installed therein and the soft film into a gas-impermeable flexible film bag,(IV) depressurizing the inside of the flexible film bag to a prescribed vacuum pressure, and(V) sealing an opening of the flexible film bag.

A pre-filled dual-chamber medical agent delivery system assembled and configured to allow delivery of a single dose of a combined therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular design consisting of separately constructed components cooperatively arranged and coupled to one another, such as to facilitate delivery of a reconstituted lyophilized agent to a patient.

This invention relates to a system flow path for solid-phase extraction and its application method. The system flow path is characterized by a pump inlet port located below a rotary valve, several solvent inlet ports on the circumference of the rotary valve, a solvent outlet port and a waste liquid port on the circumference of the rotary valve, a gas path system connecting the solvent outlet port of the rotary valve to the solvent interface of the sample loader, and a sample loader comprising a valve core and a valve body. The top of the valve body is connected to a sample vial, and a spray needle is also located at the top of the valve body. The valve core is located within the valve body. The sample flow channel is connected to a guide tube, and a membrane adapter is located below the guide tube. The membrane adapter is connected to a collection docking point, which is connected to a dehydration device and a collection vial. The collection docking point is also connected to a flow path switching system. This invention features a compact structure, anti-clogging and anti-cross-contamination advantages, and spray cleaning of the sample vial ensures complete sample loading, improving experimental recovery rates. The online filtration and dehydration functions enable full-process automation.

1. Name of the designed product: packing box (Maxigreen red bottle). 2. Use of the designed product: packing box for packing products. 3. Design points of the designed product: combination of shape and pattern. 4. Picture or photo showing the design points: perspective view.

1. The name of the design product: blister box (injection bottle). 2. The use of the design product: blister box for product packaging protection. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

1. The name of the design product: smell bottle (Y02). 2. The use of the design product: for perfume, liquor, coffee beans, essential oil, tea and other products smell sample flavor. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: design 1 perspective view. 5. Design 1 is designated as the basic design.

The utility model discloses a bottle breakage prevention device for bottle filling, and particularly relates to the technical field of filling, which comprises a lower turntable and an upper turntable fixed on the surface of the lower turntable, a motor for driving the lower turntable and the upper turntable to rotate is arranged at the bottom of the lower turntable, and the upper turntable rotates to drive penicillin bottles to move and fill. The lower rotating disc extends outwards for a certain distance from the bottom end of the upper rotating disc, a protection disc surrounding the periphery of the upper rotating disc is arranged on the lower rotating disc, a plurality of bottle grooves which are arranged at equal intervals are formed in the edge of the upper rotating disc, and penicillin bottles are embedded in the bottle grooves. The bottle opening guiding pieces and the bottle grooves are consistent in number and angle. The feeding hopper is arranged between the needle head and the penicillin bottle body in an isolation mode, the needle head can be prevented from colliding with a bottle opening or the inner wall, and even if the needle head inclines, high-speed liquid medicine ejected out cannot impact the bottle body or the bottle bottom, and the bottle body cannot be broken.

1. The name of the design product: cosmetic container bottle (double cavity vacuum vial). 2. The use of the design product: the product is used for containing cosmetics. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

This invention provides a nitrogen filling needle structure for vials, comprising a filling needle body, a first through hole penetrating its upper and lower end faces, and a filling needle body gas chamber inside the filling needle body; a top connector communicating with the first through hole at the upper end of the filling needle body; a second through hole penetrating its bottom end face at the bottom of the filling needle body, communicating with the filling needle body gas chamber; a first vent hole on the filling needle body, through which high-pressure gas passes sequentially via the top connector, the first through hole, the second through hole, and the first vent hole; a cap is fixedly installed on the bottom end face of the filling needle body at the top, with an opening at the bottom of the cap, and an annular rubber ring is provided on the inner wall of the cap, the annular rubber ring communicating with the interior of the filling needle body. This invention provides a nitrogen filling needle structure for vials, which can effectively prevent contamination of the liquid inside the vial during nitrogen filling, thereby improving the yield of finished products.

A method for injecting a therapeutic agent into a patient's skin or mucosa. The method uses a vial containing a therapeutic agent and a syringe containing a diluent comprising an aqueous solution. Attach a closed system drug transfer (CSDT) device to the syringe. Attach the CSDT device to the vial. Transfer the diluent from the syringe into the vial through the CSDT. Mix the diluent and the therapeutic agent to make a therapeutic agent solution mixture. Fill the syringe with the therapeutic agent solution mixture. The concentration of the therapeutic agent in the therapeutic agent solution mixture is ≤ 5 mg / ml. Inject the therapeutic agent solution mixture into skin or mucosa of the patient. Also disclosed are other injection methods and injection kits.

Transport system (1) for transporting sterile objects (50) in packages, in particular unsealed containers such as ampoules or vials (51), comprising a transport surface (2) on which a number (N) of sterile objects (50) to be transported can be moved, a transport unit (3) with an interaction section (4) for moving the number (N) of sterile objects (50) that can be moved on the transport surface (2) in a transport direction (T) of the transport system (1), and a recess (5) projecting from the transport surface (2) to receive the interaction section (4), wherein the transport unit (3) has a driveable positioning device (6) by means of which the interaction section (4) is adjustable relative to the transport surface (2) between a first end position (P1) and a second end position (P2), wherein in the first end position (P1) the interaction section (4) is recessed in the depression (5) in order to finally close the depression (5) flush with the transport surface (2), and wherein in the second end position (P2) the interaction section (4) is arranged in the transport direction (T) at a first distance to the recess (5) on the transport surface (2).

FIELD: pharmacology.SUBSTANCE invention can be used to determine the concentration of an anti-tuberculosis drug in blood serum. The method for determining the concentration of bedaquiline in the blood serum in patients with tuberculosis or mycobacteriosis is that whole blood samples are centrifuged at 3000 rpm for 20 minutes, then the blood plasma is collected in sterile 1.5 mL Eppendorf tubes, then 900 mcL of acetonitrile are added to 300 mcL of plasma and centrifuged at 13500g for 15 minutes, then 1 mL of the supernatant is transferred to a chromatographic vial and make the assay by UHPLC MS / MS using an Athena UHPLC C18, 1.8 mcM, 120A, 2.1×100 mm chromatography column, when using an aqueous solution containing 5 g / L of ammonium acetate, 25 ml / L of concentrated acetic acid, 2 ml / L trifluoroacetic acid as mobile phase A and 100% acetonitrile as mobile phase B, the concentration of bedaquiline is determined using a pre-plotted calibration curve.EFFECT: determination of bedaquiline in human blood plasma in a time not exceeding 6 minutes.1 cl, 9 dwg, 6 tbl

The invention provides a method and apparatus for efficiently and accurately filling vials with gaseous materials such as a fluorinated gas, with or without concomitantly filling the vials with another liquid or solid material. Also provided is a filling system for simultaneously filling a vial with a gaseous material and a liquid material using the apparatus.

The disclosed robot system may include one or more robot arms configured to transfer content, such as live fruit flies, from one vial into another. The robot arms may remove a cap from a new vial, remove a cap from a used vial, and connect the vials using a vial connector. The robot arms may shake or drop the vials to help move the content from the used vial into the new vial. The robot arms may also discard the used vial and cap the new vial after the transfer. The robot arms may also apply a new label to the new vial. Various other methods, systems, and computer-readable media are also disclosed.

The present application relates to a cartridge accommodating assembly and an injection apparatus. The cartridge accommodating assembly comprises a housing, a distal end of a medicament vial being connected with a needle cap covering a needle; an end cover, the end cover comprising an elastic clamping arm, and the elastic clamping arm being capable of cooperating with the needle cap to form a snap-fit connection; and a restricting element, located inside the housing and capable of moving relative to the housing from a first position to a second position. When the cartridge accommodating assembly is in an empty state without accommodating the medicament vial, the restricting element is maintained at the first position; when the cartridge accommodating assembly is in an assembled state in which the medicament vial is accommodated and assembled into the injection apparatus, the restricting element is maintained at the second position. When the restricting element is in the first position, the elastic clamping arm is allowed to form or disengage a snap-fit connection with the needle cap; and when the restricting element is in the second position, the elastic clamping arm is prevented from forming or disengaging a snap-fit connection with the needle cap. The present application facilitates a user in pulling the end cover out from a distal end of the housing while removing the needle cap from the distal end of the medicament vial.

A deformable container for dispensing a medical substance comprising a body defining an internal volume configured to receive a fluid substance, said body comprising a filling access configured to receive the fluid substance, a dispensing outlet configured to dispense the fluid substance, a valve arranged at the filling access movable between an open configuration and a closed configuration. The body comprises an elastically deformable wall delimiting the internal volume. The disclosure further relates to a connecting accessory comprising a first coupling portion, configured to fluidly connect to the filling access of the deformable container, and a second coupling portion configured to fluidly connect to an internal compartment of a vial. The container and the connecting accessory are configurable in a coupled configuration wherein the connecting accessory is coupled to the filling access of the container, and the valve of the container is in the open configuration.

An apparatus for securing a cap on a cylindrical container includes: a stage for separately receiving a cap and a container; an elevator movable upwardly away from the stage and downwardly toward the stage; and a cap holding assembly mounted on the elevator. The cap holding assembly comprises: a capture member platform, the capture member platform including a capture unit configured to capture the cap; at least one extendable member extending through the capture member platform, the at least one extendable member movable from a home position with the extendable member above a center of the cap captured by the capture unit and an engagement position with the extendable member engaging the center of the cap and urging the center of the cap downwardly relative to an outer sidewall of the cap; and a claw member attached to the capture member platform that is movable between an unengaged position, in which the claw member is not positioned to engage the cap, and an engaged position, in which the claw member is positioned to engage a lower edge of the cap.

A drug delivery system includes a container comprising a luer compartment and a fluid compartment, a luer fitting arranged within the luer compartment and in fluidic communication with the fluid compartment, and a dispenser in fluidic communication with the fluid compartment. A method of aseptically transferring a drug to such a drug delivery system may include providing a vial comprising the drug to be transferred, withdrawing a volume of the drug from the vial with a syringe, coupling the syringe to a drug delivery system via the luer fitting, transferring the drug from the syringe to the drug delivery system, and decoupling the syringe from the drug delivery system.

Systems and methods are provided for delivering a therapeutic treatment to a target population of cells (including, but not limited to, tumors, eyeballs, pancreatic tissue, liver tissue, and lung tissue) in a subject. The system includes an injectable aqueous solution in a vial enclosed with a septum. The solution comprises particles containing a therapeutic agent and having a coating surrounding the therapeutic agent, the coating comprising chitosan to provide controlled release of the agent from the particles. The solution also comprises a chitosan polymer in the form of a polymer gel matrix, further providing controlled release of the particles from the aqueous gel environment. There is also provided a method of making a freeze-dried powder placed in a vial containing a chitosan polymer and chitosan-coated particles, the powder when mixed with water forming the above injectable aqueous solution with particles and chitosan gel.

The present invention relates to a tamper-evident plastic closure for a medicine bottle for retaining a stopper in a mouth of the medicine bottle, comprising: a tubular locking body configured to be locked at a neck of the medicine bottle, and a cap coupled with the tubular locking body. The tubular locking body includes a retaining member to retain the stopper, and a central opening formed in the retaining member to provide access to an interior of the medicine bottle through the stopper. The cap includes a disc-shaped cover, and a coupling portion to couple the cap with the tubular locking body by a positive fit engagement. The coupling portion includes at least one frangible portion configured to be irreversibly broken by the annular frangible portion to provide access to the interior of the medicine bottle through the stopper, while at least one indicating member remains retained at an edge of the central opening of the tubular locking body as evidence of tampering after the cap is removed from a distal end of the tubular locking body.

The present invention relates to an apparatus for processing a pharmaceutical container (12), particularly a vial (14), syringe, or cartridge, comprising: a frame (54) positionable on a mounting surface (55) having a surface (63), a first side (61), and a second side opposite to the first side; at least one processing station for the container; and a particularly linear transport device (36) arranged between the first side (62) and the second side, having a retaining element (68) for the circulation of the container (12), which, at the transport section (66), extends from the receiving side to the receiving side. The transport section (66) moves in the lateral transport direction (67) and moves against the transport direction (67) at the return section (70), wherein at least one processing station (78) is arranged at the transport section (66), and the transport section (66) and the return section (70) define the transport surface (72) of the transport device (36) and are arranged above the surface (63), wherein the transport surface (72) is inclined at an angle (73) relative to the layer (65) and / or horizontal plane of the surface (63), and the transport section (66) is arranged above the return section (70) in the direction of gravity. The invention also relates to a filling device for filling a pharmaceutical container (12).

This invention discloses a membrane-based enrichment slide preparation device for rare cell samples, relating to the field of cell sample processing technology. It includes a base and a support mounted on top of the base, and further comprises: a housing with a placement stage mounted on the top; a positioning mechanism including multiple positioning cylinders rotatably mounted inside the placement stage, sample vials slidably mounted on the positioning cylinders, and filter cylinders disposed inside the sample vials; a centrifugation mechanism for driving the multiple positioning cylinders to rotate; multiple glass slides; a lifting and transfer mechanism mounted inside the housing for driving the multiple filter cylinders to rise and fall; and an adjustment mechanism for fixing and adjusting the displacement of the glass slides. By concentrating the filtered target cells on top of the membrane, and after driving the membrane to move to the bottom of the glass slide, the target cells concentrated on top of the membrane can be evenly transferred to the glass slide, improving the enrichment slide preparation effect of rare cell samples and avoiding the problem of poor slide preparation due to target cell dispersion.

The application relates to the technical field of storage equipment, and particularly provides a filling device for cryopreservation tubes, which aims to solve the technical problem of low filling efficiency in the prior art when the cryopreservation tubes are filled into a cryopreservation tube sleeve. To this end, the filling device comprises a fixing member, a tube rotating device, a tube pushing device and a limiting device which are mounted on the fixing member, the fixing member is provided with a containing cavity, a lower tube cavity and a tube pushing cavity which are communicated with the containing cavity, the tube rotating device is provided with a tube rotating cavity, the tube rotating device is located in the containing cavity and can move in the containing cavity so that the tube rotating device can be switched between a first working position and a second working position, when the tube rotating device is located in the first working position, the tube rotating cavity is communicated with the lower tube cavity, when the tube rotating device is located in the second working position, the tube rotating cavity is communicated with the tube pushing cavity, the limiting device can fix the cryopreservation tube sleeve at a first end of the tube pushing cavity, and the tube pushing device can push the cryopreservation tube transported into the tube pushing cavity into the cryopreservation tube sleeve from a second end of the tube pushing cavity.

1. Name of the product in this design: Aseptic Drug Mixer. 2. Purpose of this design: This design is used for transferring medication between vials to mix the medication between two vials. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

A method and medical device (200, 500, 600, 700, 800, 900) for mixing a medicament (106) contained within a medicament vial (210), the medical device comprising a track (220) configured to support the medicament vial, wherein the track comprises an inclined first track section (241) arranged such that, in use, the medicament vial can roll along the track to mix the medicament contained within the medicament vial.

A package (100) is provided for holding and dispensing a delivery shaft assembly (200) for delivering an implant (230), the package (100) including a vial (400) and an insert (300) mounted within a vial holding space (410), wherein the insert (300) includes: - a force receiving body (308) configured to support an adapter (210) of the delivery shaft assembly (200) during engagement with an inserter tool (500); - a delivery shaft holding mechanism (310) configured to releasably hold the delivery shaft, wherein a force applied by the inserter tool (500) during engagement with the adapter (210) actuates the delivery shaft holding mechanism (310) to release the held delivery shaft (220) for retraction of the delivery shaft assembly (200) from the insert (300) and the vial (400).

The utility model discloses a location picking tube device for cryopreservation box, including base, placing platform and detachable fixed in base location hole on the extraction pin, the placing platform is equipped with the placing hole that matches cryopreservation box and the first mounting hole that is used for being connected with base movably, the placing platform is connected with base movably through the reset subassembly, and the extraction pin is detachably fixed on the base location hole. The placing platform can move up and down relative to the base, and the cryopreservation tubes are ejected out through the extraction pins. The device is simple in design, convenient to operate and low in cost, and the cryopreservation tubes at any position of the cryopreservation box can be flexibly extracted through the detachable extraction pins; in addition, the extraction efficiency and accuracy of the target cryopreservation tube can be effectively improved through the positioning chamfers and the positioning holes; in addition, the placing holes in the placing platform can adapt to cryopreservation boxes of different designs, the cryopreservation boxes can be conveniently placed and taken, and the rectangular flanges, the chamfers and the elastic reset design of the reset assembly facilitate single-person operation so as to rapidly extract specified target cryopreservation tubes.

This application provides a mass spectrometer for easy sample loading, including a main body. A sample loading turntable is located on one side of the main body, below the sampling mechanism. The turntable includes a turntable, a sample placement tube, and multiple sets of rollers arranged in a ring at equal intervals along the outer edge of the turntable; and multiple sets of horizontal limiting components arranged in a ring at equal intervals in the middle of the sample placement tube. This application utilizes multiple sets of elastically arranged rollers arranged in a ring in the middle of the sample placement tube to fix sample vials of different diameters. A placement plate is elastically provided at the bottom of the sample placement tube, and the placement plate moves downwards via a locking mechanism. When placing sample vials of different heights, pressing the placement plate downwards ensures that the mouth height of all sample vials of different heights remains consistent. After sample loading, a release component releases the locking mechanism from the placement plate, allowing the placement plate to elastically return to its original position, facilitating repeated use and improving the practicality of the mass spectrometer.

A septum for sealing a vial assembly having a vial including a neck region including a first width includes an upper surface, a lower surface disposed opposite the upper surface, a radially extending outer surface disposed between the upper surface and the lower surface, a plurality of ribs disposed on the upper surface, and a plurality of valleys. Each valley can be disposed between at least two of the plurality of ribs to separate the at least two of the plurality of ribs. The plurality of ribs can include at least an inner first rib, an intermediate rib, and an outer outer rib. The inner first rib can include an outer wall configured to radially compress against an inner wall of the neck region of the vial, and the outer wall includes a height greater than the heights of the intermediate rib and the outer outer rib.