690 results about "Sample processing" patented technology

The invention belongs to the technical field of biological sample sorting, and discloses a visual identification control system for automatic sorting of biological samples, through cooperation of a multi-modal sensing acquisition unit and a knowledge graph multi-dimensional identification unit, condensed water of a frozen sample tube can be penetrated to accurately identify label and molecular characteristics, and'condensed water shielding 'and'label damage' are distinguished; meanwhile, a sample preprocessing state is associated, and samples which do not meet requirements are automatically intercepted. Compared with the prior art, manual secondary verification is not needed, sorting dislocation caused by optical interference of smear glass slides is thoroughly solved, the sorting precision and efficiency of mixed samples are remarkably improved, and diversified sample treatment requirements in clinical detection are met; the full-link twin operation and maintenance unit integrates key data in a sorting process through a block chain technology, and is interconnected and intercommunicated with a hospital LIS system and a sample storage system; and when the subsequent storage environment of the sample is abnormal, the quality state of the sorting stage can be reversely associated, and the compliance auditing vulnerability is eliminated.

The invention discloses a lung injury evaluation system based on a vascular endothelial cell protection effect, and the system comprises a sample processing module which is configured to execute sample preprocessing and multi-dimensional biomarker collection operation; the feature calculation module is connected to the sample processing module and is configured to perform endothelial function core index quantification and feature extraction operation; the data fusion module is connected to the feature calculation module and is configured to execute lung injury degree and endothelial protection efficiency association mapping operation; and the strategy generation module is connected to the data fusion module and is configured to execute a dynamic risk assessment and assessment strategy generation stage. The method has the following advantages and effects: systematic fusion and dynamic analysis of multi-source heterogeneous data are realized, and quantitative association mapping between biomarkers and iconography features is established, so that the comprehensiveness and predictive ability of state evaluation are remarkably improved.

The utility model provides automatic dry method sample loading equipment which comprises a workbench, a powder adding module, a rotary evaporation module, a powder scraping module and a carrying mechanism, the powder adding module, the rotary evaporation module, the powder scraping module and the carrying mechanism are arranged on the workbench, the powder adding module is used for adding needed powder into a sample container, and the sample container contains a sample; the rotary evaporation module is used for carrying out rotary evaporation on the sample added with the powder and the liquid in the sample container, so that the liquid sample and the powder sample are uniformly mixed and dried to form a powder sample; the powder scraping module is used for performing powder scraping operation on the sample container and scraping the powder sample from the inner surface of the sample container; one end of the carrying mechanism is rotationally connected with the workbench, the other end of the carrying mechanism is provided with a clamping device used for clamping materials and interaction tools, and the carrying mechanism is used for interacting among the powder adding module, the rotary evaporation module and the powder scraping module. The present disclosure also provides an automated sample processing system. According to the invention, the full-automatic unmanned process can be realized, the labor cost is reduced, and the efficiency and precision are improved.

The invention relates to the technical field of model training sample processing, in particular to a sample distribution adaptive adjustment method and system based on model training feedback driving, and the method comprises the following steps: S1, collecting feedback indexes in a training process in real time in a model training period, and obtaining a feedback index set; s2, weak item categories are analyzed and recognized based on the feedback index set, and an optimization instruction is generated; s3, dynamically adjusting the sampling weight to form an updated sampling strategy; s4, samples are collected according to a sampling strategy, and weak item category samples are supplemented; s5, putting the optimized sample set into the next round of training, and circulating the steps S1 to S4 until the training indexes of the learning effects of all key categories meet the termination condition; and acquiring a sampling strategy and a sample set. According to the method, real-time, refined and automatic sampling adjustment can be realized by taking the actual performance of model training as a core feedback index, so that the training effect and generalization ability of the model in key areas such as weak-term categories and long-tail categories are improved.

The invention discloses a method for determining the content of hydrogen ions in a chloroplatinic acid solution, and belongs to the technical field of analytical testing. In order to solve the problems that the chloroplatinic acid solution is yellow after being diluted and the manual titration end point is difficult to judge, a potentiometric titration method is adopted, and the end point is determined by measuring electrode potential mutation without depending on indicator color change. The method comprises the steps of test condition preparation, burette calibration, standard solution preparation and calibration, sample treatment and titration, result calculation and the like, a full-automatic potentiometric titrator is selected, the titration volume is controlled within the range of 10-15 mL, and a sodium hydroxide standard solution is used for sample titration after calibration. The relative standard deviation of the determination result is less than 0.5%, the adding standard recovery rate is between 96.3% and 103.1%, and the method has the characteristics of high analysis speed, high accuracy and good stability, is suitable for accurate detection of hydrogen ions in chloroplatinic acid production and quality inspection, and effectively solves the defects of the traditional method.

The invention relates to the technical field of meat quality detection, and discloses a fresh beef quality analysis system suitable for a beef jerky processing factory, which comprises a data acquisition module, a quality analysis module, a central control module, an early warning feedback module and a tracing linkage module, a sensor unit, a sample processing unit and a data preprocessing unit are integrated through a data acquisition module, and multiple physical, chemical and biological index data such as color, texture and pH value of fresh beef are acquired in real time in a non-intrusive manner by adopting a multi-source sensing technology, so that the comprehensiveness and reliability of quality analysis input are ensured; meanwhile, sample preparation and positioning are standardized through the sample processing unit, actual storage conditions of a processing plant are simulated, and the accuracy of data acquisition is improved; and a threshold value alarm unit of the early warning feedback module automatically triggers multi-level alarm according to a quality analysis result, so that real-time early warning and graded response of quality abnormal conditions are realized.

The invention relates to the technical field of life science, in particular to a full-automatic nucleic acid extraction system and process, and the system comprises a complete machine frame, a sample adding and waste liquid treatment mechanism, an oscillation magnetic suction heating mechanism, a control system and a screen interaction system. The sample adding and waste liquid treatment mechanism realizes three-dimensional accurate positioning through transverse and longitudinal movement guide rails and a vertical movement assembly, comprises a large piston device and a small piston device which are connected in parallel, and can flexibly switch different volumes of pipettes and share a connector; the oscillation magnetic suction heating mechanism integrates oscillation, heating and magnetic suction functions and is matched with multi-specification suction heads and kits to complete sample treatment. According to the extraction process, all the mechanisms are linked through a control system, and full-flow operation such as sample cracking, solid-liquid separation, magnetic bead purification and elution is automatically completed. The nucleic acid extraction device realizes automation and precision of nucleic acid extraction, improves the operation efficiency and the extraction effect, and is suitable for nucleic acid extraction of samples such as plant tissues, animal tissues, blood and plasmids.

The invention provides a high-throughput detection and bioinformation analysis and identification method for a human ring virus group, the method comprises the whole process from reference database construction, sample processing, high-throughput sequencing to bioinformation analysis, and the technical scheme specifically comprises the following steps: step 1, constructing a human ring virus high-quality reference database; 2, performing high-throughput sequencing on the metagenome of the human sample; and step 3, a ring virus group biological information analysis process.

The invention relates to the technical field of mass spectrometer sampling, in particular to a sampling device of an inductively coupled plasma mass spectrometer, which comprises a bottom plate, and an inductively coupled plasma mass spectrometer body is fixedly mounted at the top of the bottom plate. During application, the sample introduction mechanism adopts a first motor to drive a turntable to carry a sample during use, power is amplified through transmission of a large belt wheel and a small belt wheel, and a non-contact magnetic coupling drives a pumping spiral driving blade to rotate to generate negative pressure, so that automatic sample extraction, negative pressure control of opening and closing of a plugging plate and accurate control of a sample conveying channel are realized; by means of the design, carrying power is converted into pumping power, the equipment structure is simplified, the number of parts and energy consumption are reduced, the equipment operation and maintenance cost is reduced, an automatic continuous sample injection process replaces traditional single-pipe extraction, the sample injection time is greatly shortened, and the sample treatment efficiency is improved.

The invention relates to the technical field of medical diagnosis, and discloses an integrated nucleic acid detection method and device based on a micro-fluidic chip, the integrated nucleic acid detection device comprises a micro-fluidic chip module, a liquid control module, a temperature control module, an optical detection module and a data processing module, and the multiple modules work cooperatively to realize full-process automatic detection of a sample from splitting decomposition to detection; the micro-fluidic chip module comprises a sample treatment area, a nucleic acid extraction and purification area, a nucleic acid amplification area, a nucleic acid detection area and a waste liquid collection area which are connected through a micro-channel, and a valve is arranged at a key node. Through a fluid control mode combining centrifugal force and air pressure driving and valve combination of non-complex micro-pump micro-valves such as the dissolvable membrane valve, the temperature sensitive valve and the capillary force flow limiting valve, full-flow fluid sequential control can be achieved without integrating a plurality of micro-pump micro-valves; the problems of complex structure, high manufacturing difficulty and high cost caused by integration of multiple micro-pumps and micro-valves of the conventional pressure-driven micro-fluidic chip are solved.

The invention relates to the field of research on hydrogen embrittlement sensitivity of metal materials, in particular to a device for detecting hydrogen embrittlement sensitivity of a metal material in pure hydrogen and hydrogen-doped environments. The whole device is divided into an upper clamp main body and a lower clamp main body which are oppositely arranged up and down, and the upper clamp main body is provided with an upper clamp upper side through hole, an upper clamp lower side through hole, an upper clamp left side through hole, an upper clamp right side through hole and a pressed rod insertion hole. The lower part clamp main body is provided with a sample fixing groove, a sealing groove, an air cavity, a lower part clamp left side ventilation channel, a lower part clamp right side ventilation channel, a lower part clamp upper side screw hole, a lower part clamp lower side screw hole, a lower part clamp left side screw hole and a lower part clamp right side screw hole. According to the device and the method, the real working condition of contact between gas phase hydrogen and a metal material in actual engineering can be simulated, the problem of experimental cost caused by equipment requirements and sample processing can be solved, and meanwhile, the operation process of an experiment can be greatly simplified.

The invention discloses a nucleic acid detection consumable processing module, a detection system and a use method, and belongs to the field of medical examination and inspection instruments and molecular diagnosis and detection instruments, the technical key points are that the nucleic acid detection consumable processing module comprises a driving module, a temperature control and clamping integrated module, an L-shaped consumable lifting bracket and a flip module; and the driving module is used for driving the temperature control and clamping integrated module to clamp / loosen a detection chip of the consumable, driving the L-shaped consumable lifting bracket to ascend / descend and driving the flip module to rotate at the same time. The invention aims to provide the nucleic acid detection consumable processing module, the detection system and the use method, and the operation of sample processing and detection is simplified.

A system and method are provided for automatically customizing the treatment of samples in sample containers carried in a sample holder. The system and method can identify sample containers in the sample holder and / or detect various characteristics associated with the containers and / or the sample holder. This information can then be used, for example, by aspirating fluid from the sample container in a manner that takes into account the type of sample / container carrying the sample and distributing the fluid to customize the treatment of the sample.

The invention discloses a genome sequencing sample processing method based on a microdissection technology. The method comprises the following steps: (1) preparing a paraffin section or a frozen section; (2) carrying out HE staining on the section obtained in the step (1); (3) carrying out laser microdissection on nucleic acid; (4) fragmenting the DNA sample, and treating a product obtained in the step (3) by utilizing an ultrasonication method to obtain a DNA fragment; a non-contact ultrasonic crusher is adopted, the power is 80%, ultrasonic treatment is carried out for 10 s, stopping is carried out for 20 s, and 15 cycles are carried out. And (5) carrying out on-machine pretreatment on the genome sequencing sample, wherein the treatment comprises tail end repair and joint connection treatment. According to the method disclosed by the invention, accurate cutting of the sample can be realized, a DNA sample is extracted from a very small amount of cells and a sample for sequencing is constructed, the sample can achieve the same or higher sequencing data quality as that of a traditional method, the usage amount of the cells is greatly reduced, and the repeatability of an experiment is improved.

The invention discloses sampling equipment, a control method and automatic production equipment, and relates to the field of automatic sample processing equipment.The sampling equipment comprises a bottle taking device, a liquid taking device and a controller, and the bottle taking device comprises a mechanical arm, a cap screwing assembly, a sample frame and a sample bottle with a bottle cap; the liquid taking device comprises a polymerization kettle, a pressurizing assembly, a liquid taking driving assembly, a liquid taking seat, a liquid taking pipe and a liquid outlet head; the pressurizing assembly, the cap screwing assembly, the liquid taking driving assembly and the mechanical arm are electrically connected to the controller; the controller controls the mechanical arm to transfer a sample bottle to the cap screwing assembly and controls the cap screwing assembly to take down a bottle cap, the controller controls the mechanical arm to transfer the sample bottle to the liquid taking seat and controls the liquid taking driving assembly to drive the liquid outlet head to descend to a bottle opening of the sample bottle, and the controller controls the pressurizing assembly to pressurize; the polymer liquid in the liquid storage cavity flows into the sample bottle through the liquid taking pipe and the liquid outlet head. The sampling equipment provided by the invention can realize automatic and continuous sampling.

The invention relates to the technical field of superconducting material detection, and discloses a pollution-free laser pretreatment type superconducting material detection platform, which comprises a sample numerical control pretreatment assembly for pretreating a superconducting material sample; the laser smooth cleaning assembly is arranged on one side of the sample numerical control pretreatment assembly and is used for carrying out smooth cleaning on the surface of the superconducting material sample; and the performance test output assembly is arranged on one side of the laser smooth cleaning assembly and is used for carrying out resistance characteristic test on the superconducting material sample under different temperature conditions. According to the invention, the integrated series design of sample numerical control pretreatment, laser smooth cleaning and low-temperature resistance testing realizes a whole-process closed loop from sample processing, surface cleaning to performance verification, so that manual intervention and secondary pollution are reduced, the structural integrity of the superconducting material is guaranteed, the accuracy of detection data is improved through a standardized process, and the detection efficiency is improved. And performance verification, research and development and application of the high-efficiency support superconducting material.

The preparation method of the visible component microscopic examination sample comprises the following steps: preparing at least two samples with different light transmittances, and selecting at least two different sample treatment methods; comprising any two treatment methods as follows: a method A: for a light-proof to-be-detected sample, taking a set volume of light-proof sample, adding a set volume of water into the light-proof sample, and diluting to obtain an intermediate sample; taking the intermediate sample, and adding a reagent with a set volume or a set weight to obtain a microscopic examination sample; the method B comprises the following steps: for a to-be-detected semi-transparent sample, taking a semi-transparent sample with a set volume, and adding a reagent with a set volume or a set weight to obtain a microscopic examination sample; the method C comprises the following steps: enriching a light-transmitting sample with a set volume for a light-transmitting to-be-detected sample, and adding a reagent with a set volume or a set weight into an enriched intermediate sample with a set volume to obtain a microscopic sample. Corresponding methods are selected according to different light transmittances of the to-be-detected samples, so that the to-be-detected samples in different states can be prepared into microscopic examination samples suitable for efficient imaging of a microscope.

The application discloses a water quality and soil detection and analysis method and system based on multi-standard automatic evaluation and belongs to the technical field of environmental monitoring data processing. The system comprises a data import module, an intelligent identification module, a batch sample processing module, a multi-standard evaluation module, a comprehensive analysis module, a water chemistry verification module and a result output module. The system automatically analyzes the Excel table structure through an intelligent identification algorithm, extracts index names, units, detection results and background values, supports batch sample format identification, can analyze multiple samples at a time, integrates three environmental quality standards of underground water GB / T 14848-2017, surface water GB 3838-2002 and soil GB 36600-2018, automatically performs quality classification evaluation, calculates single pollution index P i , exceeding multiple, Nemerow comprehensive pollution index P N , performs water chemistry anion and cation balance verification, Shukarev classification, TDS and hardness checking, and supports single sample and batch sample export and summary table generation. The application solves the problems of weak Excel data recognition ability, batch sample processing difficulty, lack of multi-standard automatic switching, single comprehensive evaluation method and insufficient data quality checking in the prior art, and greatly improves the efficiency and accuracy of detection data analysis.

The utility model discloses a blood detection device. The blood detection device comprises a shell, test paper and a cap, the shell comprises an upper shell and a lower shell which are fixedly connected, a containing cavity is formed between the upper shell and the lower shell, the test paper is located in the containing cavity, a blood sampling head is formed at the front end of the shell, a liquid inlet is formed in the blood sampling head, and the liquid inlet is communicated with the containing cavity through a capillary structure and a premixing cavity in sequence; a hydrophobic coating belt arranged in the left-right direction is arranged on the front cavity wall of the premixing cavity, and an air hole communicated with the containing cavity is formed in the rear end of the shell; the front end of the shell is sleeved with the cap, a liquid storage bag is arranged at the bottom in the cap, and buffer liquid is stored in the liquid storage bag. The blood detection device can realize integration of sample collection and sample treatment, and has the advantages of simple structure, low manufacturing cost, convenience in use, high detection success rate, high detection accuracy and the like.

The invention relates to a kit for quantitative detection of IGF-1 (Insulin-like Growth Factor-1) and a preparation and detection method thereof. The kit comprises a calibrator, a quality control product, an internal standard solution, an immune enrichment solution, a dissociation solution, a leacheate, an eluent, a mobile phase 1 and a mobile phase 2. The complete IGF-1 protein can be fully automatically detected from top to bottom, and the sample treatment efficiency is remarkably improved; wherein the matrix liquid used for preparing the kit adopts human serum without endogenous IGF-1, so that the in-vivo environment can be simulated to the greatest extent, and the detection deviation caused by different matrixes is reduced; an eluent of the kit adopts a formic acid-hydrochloric acid mixed acid-acetonitrile system, the system can provide a mild ionization environment through formic acid, and hydrochloric acid synergistically stabilizes the synergistic effect of the pH value of the solution, so that the ion inhibition effect is reduced, the response signal of IGF-1 is improved, and the signal-to-noise ratio of detection is further improved.

This invention discloses a magnetic nano-silica, its preparation method, and its application in the enrichment of low-abundance proteins. The proposed method for preparing magnetic silica, while preserving the surface properties of silica and maintaining its protein adsorption capacity, also imparts magnetism; providing a simpler, faster, and more efficient technique for large-scale sample processing. The low-abundance protein enrichment based on magnetic nano-silica proposed in this invention can be applied to almost all sample types, effectively solving the interference caused by high-abundance proteins on the identification of low-abundance proteins during mass spectrometry detection, and increasing the number of identified proteins by 100%-700%.

A closed system centrifuge tube is described and discussed herein that enables removal of waste and transfer and removal of samples via one or more ports of the centrifuge tube within the closed system, without exposing the sample to the outer environment. This may enable greater sample retention during sample processing and centrifugation of the sample.

The invention discloses an anti-coagulation blood specimen collection oscillation device, and relates to the technical field of blood collection, and the anti-coagulation blood specimen collection oscillation device comprises a base and a main body forming the device; the movable mechanism is assembled at the upper end of the base and is used for uniformly and automatically oscillating the sample in a reciprocating manner; the locking mechanism is assembled at the upper end of the movable mechanism and is used for generating a trigger signal when the sample main body is inserted in place; according to the anti-coagulation blood sample collection oscillation device, stable positioning of a sample in the treatment process can be ensured through the locking mechanism, displacement caused by vibration or external interference is avoided, the accuracy of an experimental result is ensured, meanwhile, downward pressure is applied to help to correct the position of the sample, deviation caused by the shape of the sample or a non-uniform container is further prevented, and the sampling accuracy is improved. And the sample processing stability is improved.

The invention relates to the field of aquatic food traceability, in particular to a system for identifying wild and culture sources of bighead carps and application of the system. The system comprises: a sample processing module, wherein the sample processing module is at least used for processing a bighead carp sample to obtain original data of a polypeptide as shown in any one of SEQ ID NO.1-7, and obtaining proteome component response of a to-be-detected sample; the data processing module is at least used for importing the proteome component response of the sample to be detected into an OPLS-DA classification discriminant analysis model to obtain a score plot for discriminant analysis of subsequent sample data; and the result output module is at least used for outputting a result. The system can be effectively used for identifying wild and culture sources of bighead carps, is high in stability and specificity, does not need to use a large instrument, is low in detection cost, and has a wide application prospect in the aspect of aquatic product traceability.

The utility model relates to a combined sample division device applicable to an automatic coal sample processing line, which comprises a combined sample mixing device, a barrel washing brush, a sample barrel weighing device and a support, a combined sample feeding conveyor is fixedly mounted on the upper portion of the support, and the combined sample mixing device is mounted on the upper portion of the front end of the combined sample feeding conveyor. A scraper divider is fixedly installed on the upper side of the middle of the sample combining and feeding conveyor, a feeder abandoned sample discharging port is formed in the lower side of the rear portion of the sample combining and feeding conveyor, and a scraper divider discharging port and a second scraper divider discharging port are formed in the two sides of the scraper divider. According to the utility model, the sample blending and mixing device, the scraper splitter, the temporary storage sample conveyor and the reciprocating splitter are integrated together through the sample feeding conveyor and the material flow shaping conveyor, and the temporary storage sample conveyor and the sample incoming conveyor are matched, so that the coal sample blending and splitting processes can be integrated together, the full-process automatic treatment can be realized, and the production efficiency is improved. 24-hour continuous sample preparation is achieved, it can be effectively guaranteed that the coal samples have statistical consistency, and loss caused by manual carrying is eradicated.

The invention relates to a sample processing and training method of a monocular depth estimation model and a program product. The training sample processing method can comprise the steps that a sample image is acquired, and the sample image comprises a sample transparent object; and determining a target area where the sample transparent object is located in the sample image, and filling the target area. And inputting the filled sample image into a pre-trained monocular depth estimation model to obtain sample target depth information corresponding to the sample image, and taking the sample image and the sample target depth information as training samples of the pre-trained monocular depth estimation model. According to the technical scheme of the invention, accurate sample target depth information can be obtained. And associating the sample target depth information and the corresponding sample image as a training sample of a pre-trained monocular depth estimation model, so that the trained monocular depth estimation model can have excellent performance when estimating the depth information of the transparent object.

The application discloses a kind of methods for evaluating the delamination fracture performance of wind power blade sandwich structure, it is related to blade sandwich structure experiment and simulation field, S1: prefabricated crack sample preparation;S2: sample processing;S3: experimental test;S4: theoretical analysis;S5: simulation modeling;S6: simulation model verification;S7: interface delamination backtracking analysis;The application can accurately obtain the delamination fracture material parameters of wind power blade sandwich structure, analyze the delamination failure load of sandwich structure by simulation model, obtain interface damage, crack propagation and other information of sandwich structure, and quantitatively evaluate the resistance of blade sandwich structure to delamination crack propagation.

The application relates to the technical field of water quality detection, and particularly discloses a water quality detection device and method based on water environment pollution prevention and treatment. The device comprises a water quality sampling assembly, which is used for collecting stratified water quality samples at different depths of a water area to be detected; a sample processing assembly, which is connected with the water quality sampling assembly and is used for mixing the stratified water quality samples; a water quality data detection assembly, which comprises a first water quality data collector and a second water quality data collector; and a data processing assembly, which is electrically connected with the water quality data detection assembly, is used for processing stratified water quality index data and mixed water quality index data and outputting the data, and comprises a data preprocessing unit and a multidimensional data fusion unit which are connected with each other and are used for outputting standardized water quality data, and the multidimensional data fusion unit is used for fusing and processing the standardized water quality data, so that the detection precision of the water quality detection device is improved.