126 results about "Sample processing" patented technology

The application discloses a water quality and soil detection and analysis method and system based on multi-standard automatic evaluation and belongs to the technical field of environmental monitoring data processing. The system comprises a data import module, an intelligent identification module, a batch sample processing module, a multi-standard evaluation module, a comprehensive analysis module, a water chemistry verification module and a result output module. The system automatically analyzes the Excel table structure through an intelligent identification algorithm, extracts index names, units, detection results and background values, supports batch sample format identification, can analyze multiple samples at a time, integrates three environmental quality standards of underground water GB / T 14848-2017, surface water GB 3838-2002 and soil GB 36600-2018, automatically performs quality classification evaluation, calculates single pollution index P i , exceeding multiple, Nemerow comprehensive pollution index P N , performs water chemistry anion and cation balance verification, Shukarev classification, TDS and hardness checking, and supports single sample and batch sample export and summary table generation. The application solves the problems of weak Excel data recognition ability, batch sample processing difficulty, lack of multi-standard automatic switching, single comprehensive evaluation method and insufficient data quality checking in the prior art, and greatly improves the efficiency and accuracy of detection data analysis.

The application provides a biological analysis method capable of accurately, simply and quickly detecting the concentration of adenosylcobalamin in human serum. The method is a liquid chromatography tandem mass spectrometry method, octadecylsilane bonded silica gel is used as the column filler, the liquid phase conditions, mass spectrometry parameters and sample processing method are designed and optimized, and the application first proposes and discloses a biological analysis method capable of accurately and quickly detecting the concentration of adenosylcobalamin in human serum: after simple treatment (need to avoid light) such as protein precipitation and nitrogen blowing dry, the sample can be injected, the analysis time is only 4.00 min, the lower limit of quantification is as low as 5 pg / mL, and the sample dosage is only 100 muL. The application can quickly monitor the change of vitamin B12 in the body, meet the requirements of adenosylcobalamin in vivo drug monitoring, pharmacokinetics and bioequivalence, and can effectively improve the safety and reliability of the drug.

The application discloses a kind of methods for evaluating the delamination fracture performance of wind power blade sandwich structure, it is related to blade sandwich structure experiment and simulation field, S1: prefabricated crack sample preparation;S2: sample processing;S3: experimental test;S4: theoretical analysis;S5: simulation modeling;S6: simulation model verification;S7: interface delamination backtracking analysis;The application can accurately obtain the delamination fracture material parameters of wind power blade sandwich structure, analyze the delamination failure load of sandwich structure by simulation model, obtain interface damage, crack propagation and other information of sandwich structure, and quantitatively evaluate the resistance of blade sandwich structure to delamination crack propagation.

This utility model relates to the field of life science technology, and in particular to a nucleic acid extraction device. The device includes a frame, a sample loading and waste liquid treatment mechanism, a oscillating magnetic heating mechanism, a control device, and a screen interaction system. The sample loading and waste liquid treatment mechanism achieves precise three-dimensional positioning through horizontal and vertical motion guides and vertical moving components. It includes parallel large and small pistons, allowing for flexible switching between different volume pipetting and sharing a common connector. The oscillating magnetic heating mechanism integrates oscillation, heating, and magnetic attraction functions, and works with various sizes of pipette tips and reagent kits to complete sample processing. The extraction process is automated through the control device, linking all mechanisms to automatically complete the entire process, including sample lysis, solid-liquid separation, magnetic bead purification, and elution. This application automates nucleic acid extraction, improving operational efficiency and extraction results, and is suitable for nucleic acid extraction from plant tissues, animal tissues, blood, plasmids, and other samples.

This invention discloses a gene detection method and gene detection cartridge based on magnetic control technology, comprising: setting a capillary magnetic bead moving channel, a sample processing chamber, and an amplification chamber within the detection cartridge; the sample processing chamber and the amplification chamber are separated into one or more cleaning zones by a high-viscosity liquid substance or a thermoplastic hydrophobic substance through the capillary magnetic bead moving channel; adding the sample to the sample processing chamber, mixing the sample with sample processing reagents and nano-magnetic beads, adsorbing nucleic acids by the nano-magnetic beads, and having an external magnet adsorb the nano-magnetic beads and drive them along the capillary magnetic bead moving channel sequentially through the cleaning zones into the amplification chamber; eluting the nucleic acids in the amplification chamber and performing an amplification reaction; and detecting the amplified fluorescence signal through an external optical device to achieve integrated nucleic acid extraction, amplification, and detection. This invention improves the integration of the detection cartridge, reduces manufacturing costs, and increases product yield through optimized design of capillary liquid isolation and flow channel degassing technology.

This invention belongs to, but is not limited to, the field of industrial visual inspection technology, and discloses a visual inspection system and method based on automatic defect sample annotation and online model updating. It includes a multi-station parallel inspection unit, an intelligent loading and unloading unit, a product flow and rejection unit, a sample processing and model optimization unit, a data interaction unit, and a core control module. The multi-station parallel inspection unit enables multi-dimensional parallel defect detection; the intelligent loading and unloading unit completes precise loading and unloading; the product flow and rejection unit achieves graded sorting; the sample processing and model optimization unit achieves online model updating through sample screening, automatic annotation, and incremental training; the data interaction unit achieves data closure; and the core control module ensures system stability. The method includes seven steps, such as initial configuration and intelligent loading and unloading. This invention improves inspection efficiency and accuracy, reduces annotation costs, and adapts to the dynamic inspection needs of industry.

This application provides an identification method, comprising: acquiring an original image of a blood collection tube under blue light illumination; performing a channel separation operation on the original image to obtain a first image based on the signal of the green light channel and a second image based on the signal of the blue light channel, wherein the blood collection tube contains a centrifuged blood sample; identifying the total height of the centrifuged blood sample based on the grayscale distribution of the first image; and identifying the height of the white film layer in the centrifuged blood sample based on the grayscale distribution of the second image. This application also provides a pipetting method, a storage medium, and a sample processing system.

The application discloses a test method for CTOD resistance curve of high-grade pipeline steel, and relates to the technical field of pipeline steel, in particular to a test method for CTOD resistance curve of high-grade pipeline steel. The application discloses a test method for CTOD resistance curve of high-grade pipeline steel, which comprises the following steps: sample processing is performed on the material to be tested; the sample is selected through sample processing; the temperature of the sample is controlled within a set range by a testing machine; a pre-crack is made on the sample according to the length of the sample; a CTOD test is performed through a multi-sample method to obtain data points meeting the requirements; and the experimental data points are fitted to obtain a fitting curve. The test method provided by the application can quickly and accurately determine the displacement values of each point in the CTOD resistance curve, save a large amount of test time, standardize the test method for the CTOD resistance curve, and enable the test results of the CTOD resistance curve obtained by each laboratory to be directly compared.

The application provides an aviation non-metal material sample processing device and method, which comprises a positioning clamp including a fixed part and a movable part which can be relatively moved and jointly form a clamping space containing multiple samples; multiple samples are clamped and fixed in the clamping space; at least one first prefabricated groove is formed in the side of the movable part; a saw blade is arranged on one side of the positioning clamp, and the cutting plane of the saw blade is vertically arranged with the center height of the first prefabricated groove; the saw blade can simultaneously cut multiple samples along the vertical height, and second prefabricated grooves corresponding to the first prefabricated groove are formed on the multiple samples; when the saw blade passes through the first prefabricated groove on the clamp, synchronous cutting is performed on all clamped samples. The cumbersome process of the traditional method is changed, the machining efficiency is improved, all samples are machined in the same device, the same saw blade and the same process, and the machined notches and prefabricated cracks have high batch consistency in size, shape and relative position.

The present application relates to the field of automation control technology, in particular to a mass spectrometric detection reagent sample pretreatment method and system, comprising the following steps: calling sensor to detect reagent viscosity and density, adjusting liquid suction pressure rhythm, analyzing light transmission deviation to judge mixing state, monitoring temperature to adjust oscillation heating parameters, analyzing film sealing stress data to adjust pressing posture, collecting waste gas concentration to adjust exhaust frequency. In the present application, by analyzing reagent characteristics and liquid suction pipeline parameters, liquid suction pressure and timing are accurately calibrated, light transmission characteristics are analyzed by multi-path light beam irradiation, mixed balanced state is automatically determined, mixed balanced degree is accurately optimized, heating area temperature difference is synchronously monitored, heating process parameters are real-time regulated, the consistency of temperature control oscillation is improved, film sealing pressing angle is real-time optimized by using stress data, film sealing quality is improved, exhaust frequency is dynamically adjusted by analyzing the matching degree between waste gas concentration and negative pressure stability trend, and the stability of sample processing process is effectively ensured.

The application discloses a portable detection kit for assisting in predicting a cerebral vascular risk, a blood sample is processed through a sample processing module and input corresponding test paper, a detection result of the test paper is collected by a biological sensing module, and the detection result is calibrated and temporarily stored through an electronic control module, so that a user can acquire the calibrated detection result through a target device in an NFC touch mode and automatically send the calibrated detection result to a cerebral vascular disease monitoring digital platform, cerebral vascular risk prediction is performed by the cerebral vascular disease monitoring digital platform, and the portable detection kit has the beneficial effects of high portability, simple operation and high detection result accuracy.

This application provides a liquid analyzer and its automatic pipette tip selection detection method and storage medium. The method includes: acquiring consumable information and detection task information; the consumable information includes pipette tip model, available quantity of pipette tips, mixing cup specifications, and available quantity of mixing cups; the detection task information includes the detection items to be performed and the sample type; determining the sample volume and sample processing liquid volume that meet the pipetting conditions based on the detection task information and the detection method corresponding to the detection items; obtaining the pipetting coefficient of variation based on the sample type, sample volume, and sample processing liquid volume; selecting a target pipette tip model that meets preset detection conditions based on the pipetting coefficient of variation and the consumable information; and selecting the corresponding target pipette tip to perform the detection task and obtain the detection result. This method can reduce detection errors caused by improper pipette tip selection and effectively improve the accuracy and efficiency of detection.

The utility model relates to soil detection technical field especially relates to a sample processing device for soil detection, including the drying box that a plurality of groups of electric heating wire are installed to inner wall, drying box one side is installed with the cabinet door, the drying box top inner wall center rotation is connected with the mounting rod, the drying box inner wall is provided with a plurality of groups of the tray for placing sample, tray bottom fixedly connected with the baffle that drying box size is compatible, the baffle and tray middle part all are penetrated with the through groove that mounting rod size is compatible, the baffle is provided with adjusting assembly with mounting rod junction, drying box bottom fixedly connected with the base, the base inside is provided with drive assembly. The utility model not only can make the device can adjust the space size of drying cavity, to make it can be applicable to different types and specifications of sample drying work, but also can make the device can drive the tray rotation, to make sample can be in contact with heat source evenly, effectively guarantee drying quality.

This application discloses a reaction control device for a centrifugal microfluidic chip, relating to the field of in vitro diagnostic technology. The device includes: a chip holder for mounting the centrifugal microfluidic chip, which can accommodate a sample to be tested; a drive module connected to the chip holder and capable of rotating the chip holder; a heating and temperature control module connected to or located on one side of the chip holder, capable of controlling the temperature of the centrifugal microfluidic chip on the chip holder; a fluorescence detection module located below the chip holder, used to detect the reaction of the sample to be tested, wherein the chip holder has fluorescence detection holes adapted to the fluorescence detection module; and a magnetic bead manipulation module adapted to the heating and temperature control module, used to assist in the processing of the sample to be tested. This application achieves integrated operation of the centrifugal microfluidic chip from sample processing and reaction control to result detection through the organic integration and coordinated control of multiple modules.

The utility model relates to aquatic product breeding technical field discloses a kind of before processing device of macrobrachium rosenbergii sample, including shell, the inside of shell is provided with reciprocating motion component, and the inside bottom surface of shell is fixedly connected with side plate, the outer surface of side plate is installed with frequency conversion motor, the output shaft of frequency conversion motor is fixedly connected with synchronous pulley one, the outer surface transmission of synchronous pulley one is connected with synchronous belt, synchronous belt transmission is connected with synchronous pulley two, the inside of synchronous pulley two is connected with the rotating rod of insertion, the top of shell is connected with cover plate by screw.The utility model can be inserted multiple test tubes containing macrobrachium rosenbergii pancreas sample at one time by setting multiple jacks on placing table, meanwhile, cooperate four reciprocating motion components, under the driving of frequency conversion motor, can make multiple test tubes sample and solvent fully oscillate, compared with single sample processing single sample, greatly improve processing efficiency, also enhanced the uniformity of oscillation, guarantee sample processing effect.

This utility model discloses a gross image acquisition device for biological samples, comprising: a sample processing platform, including a sample box and a loading platform, the loading platform being placed inside the sample box; the loading platform includes sample fixing nails and a pad, with hollow samples cut open to fully expose lesions and placed on a silicone single plate; solid samples, after being cut open, are placed on the silicone pad, and the sample is properly fixed to the silicone pad using the sample fixing nails. The image acquisition device includes a shadowless light source and a camera, with the shadowless light source surrounding the camera, the camera being mounted directly above the loading platform; a wireless transmission device directly transmits the images acquired by the camera to an image processing computer in real time via Bluetooth; the image processing computer has the function of reading, processing, and displaying sample images. This utility model can capture, transmit, and process images of gross specimens of biological samples to be tested, and can obtain clear and complete gross images of the surface and cross-section of biological samples.

The application discloses a lung injury evaluation system based on vascular endothelial cell protection, which comprises a sample processing module configured to perform sample pretreatment and multi-dimensional biomarker collection operation; a feature calculation module connected to the sample processing module and configured to perform endothelial function core index quantization and feature extraction operation; a data fusion module connected to the feature calculation module and configured to perform lung injury degree and endothelial protection efficiency correlation mapping operation; and a strategy generation module connected to the data fusion module and configured to perform dynamic risk assessment and evaluation strategy generation stage. The application has the following advantages and effects: through systematic fusion and dynamic analysis of multi-source heterogeneous data, quantitative correlation mapping between biomarkers and imaging features is established, thereby significantly improving the comprehensiveness of state evaluation and prediction ability.

This invention relates to the field of biosensing technology, providing a self-driven sorting device with a near-field direct-write gradient grid and its fabrication method. The invention aims to solve the problems of existing microfluidic sorting devices, such as reliance on external power, susceptibility to stacking and clogging, and severe human background interference. The device constructs a spatially heterogeneous geometric topological grid in situ on a porous substrate using a near-field direct-write process, forming a three-level gradient path consisting of a primary coarse filtration zone, a secondary sorting zone, and a tertiary retention zone. This invention utilizes substrate capillary forces to drive sample flow and achieves physical guidance and precise retention of human cells through a deterministic lateral displacement mechanism. While significantly increasing sample processing throughput, it drastically reduces the proportion of human reads in sequencing, providing a convenient and efficient technical platform for automated preprocessing of complex biological samples and high-sensitivity clinical detection.

The application discloses a kind of full-automatic nucleic acid detection analysis system and method, it belongs to medical examination testing instrument, molecular diagnostic detection instrument field, its technical key points are in at, including: consumable operation executor, it is connected with the rotating liquid transfer device of consumable and can drive rotating liquid transfer device rotation and lift and provide the power of liquid suction and liquid discharge for rotating liquid transfer device;Carriage assembly, for carrying and positioning consumable;Function warehouse processing component, for heating, magnetic separation, mixing operation of the magnetic bead lysis liquid warehouse of consumable;Reaction tube temperature control component, for the temperature adjustment of amplification reaction for consumable reaction tube;Optical assembly, for the fluorescence optical detection of solution in the reaction tube of consumable.The application aims to provide a kind of full-automatic nucleic acid detection analysis system and method, can realize sample processing, amplification, detection integrated operation.

A kind of small and micro customer credit rating modeling method based on Logistic-AHP-K factor, the method includes: step S1, sample data is obtained after selecting sample processing, and the sample data is preprocessed, and preprocessing data is obtained;Step S2, model design based on preprocessing data;The model includes: statistical model, expert model and fusion model.The present application has the advantages of balance of interpretability and model science.

The utility model relates to the technical field of biomedical engineering discloses an optical marking device for high-precision sample positioning, the utility model discloses a case, exhaust component sets up at the top of case, including gas collecting hood, sets up two groups, and is located the both sides of top of case, washing module sets up in the outer wall of one side of case, including water tank, sets up in the inside bottom end of case, still include washing bin, bolt connection in the outer wall of one side of case, and washing bin one side bottom is provided with valve, integrated exhaust and washing module, has improved the security and environmental protection of biological sample processing process obviously. Its core technical effect lies in that the waste gas and waste liquid generated in the optical marking process are effectively controlled and treated, and the cleanliness of the laboratory environment and the safety of the operating personnel are ensured.

The application discloses an HDPE particle on-line sampling device and a sampling method, and belongs to the technical field of polyolefin production detection, which comprises a raw material bin, further comprises a sampling unit, a sealed conveying unit, a sample processing unit, a linkage control unit and an OCS on-line analysis unit, the sampling unit is connected with the sealed conveying unit, the sealed conveying unit is connected with the raw material bin, the sample processing unit is connected with the linkage control unit, the linkage control unit is connected with the OCS on-line analysis unit, the OCS on-line analysis unit is connected with the raw material bin, the sampling unit, the sample processing unit and the OCS on-line analysis unit are electrically connected with the linkage control unit, and the technical problems that the existing HDPE particle sampling mode has poor sample representativeness, is easy to cause material leakage in a sampling process and cannot realize real-time detection by linkage with an OCS on-line analysis system are solved.

This invention relates to the field of sample detection technology, and particularly to an integrated sample processing and detection system and method. The system includes a base, which includes a mounting platform and a support frame mounted thereon. A moving track is provided on the support frame, and the moving track forms a module installation line in the projection area on the mounting platform. The module installation line has several sample placement slots for placing reaction cups. The detection module includes at least two detection mechanisms located on the module installation line, which are biochemical analysis detection mechanisms, specific protein analysis detection mechanisms, or chemiluminescence analysis detection mechanisms. The sampling module includes a main moving component and a main sampling needle mounted thereon. The main moving component is slidably connected to the moving track to drive the main sampling needle to move along the module installation line between the sample placement slots and the detection mechanisms. This configuration simplifies the sample processing and detection process, reduces costs, and saves space.

The utility model provides a kind of pretreatment module and sample processing system, setting up from loading site corresponding to sample track by uncapping module, to integrate uncapping site and loading site into same physical site, and loading site can block sample seat, to carry sample tube on sample seat and stay on loading site, to carry out uncapping operation to the sample tube by uncapping module, loading site releases sample seat after the sample tube completes uncapping, realizes the sample tube of sample, without transferring sample tube between uncapping site and loading site;In this way, without setting two sets of sample transfer manipulator and two sets of transfer control process respectively complete sample tube uncapping travel and loading travel transfer, system architecture and control can be simplified, cost is reduced, and sample processing efficiency can be improved, while sample overflow and pollution can be avoided in the process of transferring completed uncapping sample tube from uncapping site to loading site, to improve the reliability of system.

The application belongs to the technical field of food detection and molecular diagnosis, and particularly relates to a molecular diagnosis system for food source component identification. The system comprises a handheld shell, and an automatic sample processing unit, a molecular detection unit, a central control unit and a data transmission unit are integrated in the shell. The automatic sample processing unit comprises at least two processing modules and an automatic transfer mechanism, which are used for crushing, lysing and automatic transfer of a solid sample, and an in-situ cleaning and disinfecting assembly is integrated. The application realizes full-process automation, handholding and intelligence from a solid sample to a detection result, and provides an innovative solution for food safety on-site rapid detection and intelligent supervision.

The application relates to the technical field of biological detection, and particularly discloses a rapid detection kit for Helicobacter pylori and an application method thereof; the kit comprises a sample processing liquid, an antigen pre-enrichment particle suspension and an immunochromatography test paper card; the sample processing liquid comprises an antigen-induced release system, a composite lysis system, a matrix interference blocking system and a chromatography promoter; the antigen pre-enrichment particle is a magnetic nanoparticle with an anti-Helicobacter pylori antibody coupled on the surface; and the immunochromatography test paper card is provided with a first detection line, a second detection line and a quality control line on a nitrocellulose membrane in sequence. The antigen is mildly and efficiently released through the antigen-induced release system, the bacterial cell wall is synergistically lysed through non-ionic and anionic surfactants, the interference substance is blocked through a double mechanism of a protein blocking agent and a metal ion chelating agent, the low-abundance antigen is enriched through the magnetic nanoparticle, and the sample effectiveness is monitored through the second detection line.

The application discloses a kind of early warning screening systems of critical patient based on CI-TOFMS detection exhaled air VOCs, belong to early screening field.It includes sample processing system, CI-TOFMS, data processing module;The sample processing system is used to collect and pre-process exhaled air sample, the CI-TOFMS is used to detect exhaled air sample and obtain eVOCs spectrum, the data processing module is used to collect eVOCs spectrum data, and output early warning result;The data processing module includes data input module, eVOCs-based critical illness prediction model and result output module.The system of the application only needs to collect respiratory air to carry out the health status evaluation of test person, and it is very convenient.The eVOCs-based critical illness prediction model constructed further improves the accuracy and sensitivity of eVOCs detection technology in critical patient diagnosis, and provides more reliable diagnostic basis for clinicians.

This invention discloses a sample sorting device and method, belonging to the field of sample processing technology. In the sample sorting device, a loading / unloading mechanism moves the culture dishes between a storage station and a picking station; a shifting mechanism grips or releases the culture dishes and moves them between various stations; a positioning mechanism includes a lid-placement station and a placement station, the placement station for placing the culture dishes and clamping their bottom boxes, and the lid-placement station for placing the lids of the culture dishes; a detection mechanism for detecting the samples contained in the baskets within the culture dishes; and a sorting mechanism for moving the baskets from one culture dish to another. The sample sorting method, using the aforementioned sample sorting device, achieves automatic sample sorting through the coordinated operation of the loading / unloading mechanism, shifting mechanism, positioning mechanism, detection mechanism, and sorting mechanism, reducing labor intensity and experimental costs, improving experimental efficiency, and meeting the sorting needs of large quantities of samples.

The present application relates to the technical field of petroleum and natural gas geophysical exploration, and discloses a shale plug sampling method.The shale plug sampling method comprises the following steps: S1, determining a core processing position in a well; S2, performing multidirectional sample processing to obtain a plurality of sample plugs; S3, judging whether the sedimentary characteristics of the plurality of sample plugs are consistent; if the sedimentary characteristics are inconsistent, returning to step S2; if the sedimentary characteristics are consistent, proceeding to the next step; S4, judging whether the physical characteristics of the plurality of sample plugs are consistent; if the physical characteristics are inconsistent, returning to step S2; if the physical characteristics are consistent, obtaining a target shale plug.The shale plug sampling method is suitable for remote and simple sampling environments, does not require laboratory precision measurement, and can obtain a plug sample with good consistency through simple operation, thereby ensuring that the multidirectional shale plug samples come from the same position in a core.

The present disclosure relates to cell processing technology. As an example, a cell processing system can include a plurality of sample processing devices configured to process patient samples and a plurality of readers associated with the plurality of sample processing devices, respectively, wherein each reader is configured to read information from a tracking device associated with a respective patient sample. The system can also include a controller that uses information from the readers to provide an estimated completion time for a patient sample based on availability of the sample processing devices.