1248 results about "Sample processing" patented technology

The invention belongs to the technical field of biological sample sorting, and discloses a visual identification control system for automatic sorting of biological samples, through cooperation of a multi-modal sensing acquisition unit and a knowledge graph multi-dimensional identification unit, condensed water of a frozen sample tube can be penetrated to accurately identify label and molecular characteristics, and'condensed water shielding 'and'label damage' are distinguished; meanwhile, a sample preprocessing state is associated, and samples which do not meet requirements are automatically intercepted. Compared with the prior art, manual secondary verification is not needed, sorting dislocation caused by optical interference of smear glass slides is thoroughly solved, the sorting precision and efficiency of mixed samples are remarkably improved, and diversified sample treatment requirements in clinical detection are met; the full-link twin operation and maintenance unit integrates key data in a sorting process through a block chain technology, and is interconnected and intercommunicated with a hospital LIS system and a sample storage system; and when the subsequent storage environment of the sample is abnormal, the quality state of the sorting stage can be reversely associated, and the compliance auditing vulnerability is eliminated.

The invention provides a TEM sample and a preparation method and application thereof.According to the preparation method of the TEM sample, on the premise that the hole structure of a semiconductor device is not affected, part of residual polymer accumulated and blocked in a hole opening in the semiconductor device is removed through reactive ion etching, so that the hole opening is expanded and not blocked any more; a protective colloid can enter a pore structure for filling and precursor material plating of atomic layer deposition is facilitated, the definition of the side wall of the pore is enhanced, and the quality and the final observation effect of the TEM sample are effectively improved; the equipment and technology adopted by the preparation method of the TEM sample provided by the invention are low in investment, and the operation process is simpler and faster than that of a Fab etching process; meanwhile, batch laboratory-scale sample treatment can also be realized; in addition, compared with a wet chemical corrosion cleaning technology for removing residual polymers, the problems of chemical reagent residues, chemical reactant pollution and the like at the bottom of the deep hole structure are avoided.

The invention discloses a method for measuring the particle size of metal powder by using a scanning electron microscope, which comprises the following steps: step 1, sample treatment: adhering a small conductive adhesive tape on a sample table, sprinkling metal powder on the adhered conductive adhesive tape, and purging to obtain the conductive adhesive tape adhered with the metal powder; step 2, parameter setting: setting acceleration voltage, working distance, diaphragm, image contrast, brightness, magnification times and scanning speed of a scanning electron microscope to observe the conductive adhesive tape adhered with the metal powder obtained in the step 1 to obtain an electronic image of metal powder particles; and processing and calculating the electronic image of the metal powder particles by using software to obtain the average particle size of the metal powder particles. According to the method disclosed by the invention, a solvent is not needed to disperse the sample, pollution of the solvent to the sample is effectively avoided, and the result is more accurate than that of directly measuring the particle size by using length software.

The invention discloses a lung injury evaluation system based on a vascular endothelial cell protection effect, and the system comprises a sample processing module which is configured to execute sample preprocessing and multi-dimensional biomarker collection operation; the feature calculation module is connected to the sample processing module and is configured to perform endothelial function core index quantification and feature extraction operation; the data fusion module is connected to the feature calculation module and is configured to execute lung injury degree and endothelial protection efficiency association mapping operation; and the strategy generation module is connected to the data fusion module and is configured to execute a dynamic risk assessment and assessment strategy generation stage. The method has the following advantages and effects: systematic fusion and dynamic analysis of multi-source heterogeneous data are realized, and quantitative association mapping between biomarkers and iconography features is established, so that the comprehensiveness and predictive ability of state evaluation are remarkably improved.

The invention discloses a method and a system for assisting rice breeding by using a lodging-resistant index, particularly relates to the field of agricultural breeding, and quantifies the lodging-resistant capability of plants by constructing an evaluation model fused with multi-source phenotypic parameters. Key character data are obtained by combining mechanical testing, manual measurement and unmanned aerial vehicle image acquisition, an LRI index is calculated through standardization processing and image recognition, resistance grading is conducted, and lodging-resistant breeding material screening is achieved. According to the method and the system for assisting rice breeding by using the lodging-resistant index, digitization and intellectualization of a rice lodging resistance evaluation process are realized, and scientificity and efficiency of evaluation are remarkably improved. And by introducing an unmanned aerial vehicle remote sensing and image recognition algorithm, the large-scale sample processing capability is improved, and the timeliness and stability of data acquisition are enhanced. A lodging risk thermodynamic diagram and a recommended breeding list can be output through a matched visual analysis function, visual reference is provided for researchers and breeding decisions, and the method has good application and popularization prospects.

The invention discloses a micro-plastic integrated intelligent detection device, which comprises: a sample pretreatment module, which comprises a sample mixing module, a filtering separation module, an enrichment concentration module and a surface modification and marking module which are communicated in sequence and is used for mixing, filtering, enriching, modifying and marking a sample in sequence; the immunoreaction module is used for performing immunoreaction on the sample and the anti-polystyrene monoclonal antibody freeze-dried product marked by the quantum dot fluorescent microspheres; the fluorescence detection module is used for carrying out fluorescence detection on the test strip subjected to the immune reaction; the automatic control module is electrically connected with the sample pretreatment module, the immunoreaction module and the fluorescence detection module and is used for controlling the operation of each module. According to the invention, the sample processing module, the reaction module, the detection module and the control module are in close cooperation, the sample enters each module in sequence after simple pretreatment, detection and result output are semi-automatically completed, frequent manual operation of different instruments is not needed, the operation steps and time are reduced, and the operation difficulty is reduced.

The invention discloses a positive pressure antifouling gamma-ray spectrum automatic monitoring square cabin, and relates to the technical field of nuclear emergency monitoring and square cabins, the positive pressure antifouling gamma-ray spectrum automatic monitoring square cabin comprises a cabin body, a transition cabin is arranged in the cabin body, the transition cabin divides the interior of the cabin body into a sealed measurement cabin and a sample preparation cabin, and one side of the transition cabin is provided with an air-tight door capable of communicating the sealed measurement cabin with the sample preparation cabin; a sample conveying cabin used for allowing a sample to go in and out of the sealed measuring cabin and the sample preparation cabin is arranged on the side, away from the airtight door, of the inner wall of the transition cabin, the cabin body is overall designed into three areas, and the to-be-detected sample treatment area and the electric refrigeration high-purity germanium gamma-ray energy spectrometer are effectively isolated; filtered clean air is continuously introduced into the measurement cabin, the pressure in the sealed measurement cabin is maintained to be greater than the external pressure, the requirements of air cleanliness and positive pressure are ensured, and the background of the surrounding environment of the electric refrigeration high-purity germanium gamma-ray energy spectrometer is prevented from being changed after external radioactive pollution air enters the sealed measurement cabin, so that the measurement is prevented from being influenced.

The utility model provides a handheld micro-fluidic sample processing device. The handheld micro-fluidic sample processing device comprises a clamp upper plate, a gas circuit connecting plate, a joint sealing plate, a chip sealing plate, a micro-fluidic chip and a clamp lower plate which are sequentially stacked from top to bottom, the upper clamp plate is provided with a hollowed-out area used for being connected with the second positioning hole of the lower clamp plate. The gas circuit connecting plate is provided with a plurality of gas circuit connecting ports which are densely arranged and first positioning holes which are connected with the clamp lower plate; the joint sealing plate is provided with a joint connecting port corresponding to the gas path connecting port of the gas path connecting plate and a third positioning hole for fixing the chip sealing plate; the chip sealing plate is provided with a liquid storage tank which is arranged corresponding to the joint connecting port of the joint sealing plate; the micro-fluidic chip comprises a chip main body and a reaction substrate, and a chip positioning area for placing the micro-fluidic chip is arranged on the clamp lower plate. According to the utility model, the hardware cost is reduced, and various functional operations can be satisfied.

The invention discloses a preparation device of an electron microscope sheet sample, and belongs to the field of test and measurement. The cutting unit and the grinding unit are integrally arranged, and the feeding unit penetrates through the cutting unit and the grinding unit, so that feeding, cutting and grinding of samples can be sequentially completed by one set of device, the samples do not need to be transferred among different devices, and the sample processing quality is also improved while the sample processing efficiency is improved; in the whole set of preparation device, the working mode that the feeding unit and the grinding unit work simultaneously, the cutting unit and the receiving cavity discharge work simultaneously, and the feeding unit and the grinding unit as well as the cutting unit and the receiving cavity work alternately is achieved, and the adjacent units work alternately; according to the transmission electron microscope slice sample processing device, the preparation cohesion of feeding, cutting, grinding and discharging of a single sample is ensured, and synchronous operation of all unit components in the whole device is also ensured, so that continuous online production of transmission electron microscope slice samples can be realized, and the processing efficiency is favorably improved.

A sample processing method includes: obtaining a positive sample image; obtaining, based on the positive sample image, an anomaly labeling mask map corresponding to the positive sample image; and generating a forged negative sample image based on the positive sample image and the anomaly labeling mask map, where an anomaly region in the forged negative sample image corresponds to an anomaly labeling region in the anomaly labeling mask map. In this way, a large quantity of forged negative sample images can be automatically generated, to provide sufficient sample datasets for task detection in a scenario with scarce samples.

The invention provides a traditional Chinese medicine extract component detection method and system, and relates to the field of traditional Chinese medicine detection. The component detection system for the traditional Chinese medicine extract comprises a sample preparation module used for pretreatment of dissolution and dilution of a sample and treating the traditional Chinese medicine extract sample into a solution state suitable for chromatographic analysis; the multi-dimensional chromatographic separation module comprises a first-dimensional chromatographic column, a second-dimensional chromatographic column, a pump and a sample injector, and is used for effectively separating different components in the complex traditional Chinese medicine extract sample so as to facilitate subsequent detection and analysis. The separation degree of a complex traditional Chinese medicine extract sample can be effectively improved by utilizing the selectivity difference of different chromatographic columns through a multi-dimensional chromatographic separation technology, meanwhile, the analysis time can be shortened and the analysis efficiency can be improved by optimizing the mobile phase composition and the gradient elution procedure, the sample loss can be reduced through multi-dimensional chromatographic separation, and the detection accuracy is improved. And the detection sensitivity and accuracy are improved.

The invention belongs to the technical field of chemical analysis of metallurgical standard samples, and discloses a super duplex stainless steel spectrum standard sample with high quality, high uniformity, high stability and accurate fixed value and a development method thereof. The method comprises the following steps: component design and raw material proportioning, smelting and casting, forging and homogenization treatment, primary inspection of uniformity and sample processing, uniformity inspection, constant value analysis and mathematical statistics, determination of characteristic values of standard samples, stability analysis of the standard samples after long-term storage, and traceability guarantee measures. The super duplex stainless steel spectrum standard sample comprises the following components in percentage by mass: 25%-26% of Cr, 6.50%-7.50% of Ni, 3.50%-4.50% of Mo, 0.23%-0.27% of N, 0.5%-1.0% of Cu, 0.5%-1.0% of W, and the balance of iron and inevitable impurities, and the content of trace elements including sulfur, aluminum and boron is controlled in a specific ppm level range.

The utility model provides automatic dry method sample loading equipment which comprises a workbench, a powder adding module, a rotary evaporation module, a powder scraping module and a carrying mechanism, the powder adding module, the rotary evaporation module, the powder scraping module and the carrying mechanism are arranged on the workbench, the powder adding module is used for adding needed powder into a sample container, and the sample container contains a sample; the rotary evaporation module is used for carrying out rotary evaporation on the sample added with the powder and the liquid in the sample container, so that the liquid sample and the powder sample are uniformly mixed and dried to form a powder sample; the powder scraping module is used for performing powder scraping operation on the sample container and scraping the powder sample from the inner surface of the sample container; one end of the carrying mechanism is rotationally connected with the workbench, the other end of the carrying mechanism is provided with a clamping device used for clamping materials and interaction tools, and the carrying mechanism is used for interacting among the powder adding module, the rotary evaporation module and the powder scraping module. The present disclosure also provides an automated sample processing system. According to the invention, the full-automatic unmanned process can be realized, the labor cost is reduced, and the efficiency and precision are improved.

Provided herein are methods for processing and / or detecting a sample. A method can comprise providing a barrier between a first region and a second region, wherein the first region comprises the sample, wherein the barrier maintains the first region at a first atmosphere that is different than a second atmosphere of the second region, wherein a portion of the barrier comprises a fluid in coherent motion; and using a detector at least partially contained in the first region to detect one or more signals from the sample while the first region is maintained at the first atmosphere that is different than the second atmosphere of the second region. The portion of the barrier comprising fluid may have a pressure lower than the first atmosphere, the second atmosphere, or both.

The invention relates to the technical field of model training sample processing, in particular to a sample distribution adaptive adjustment method and system based on model training feedback driving, and the method comprises the following steps: S1, collecting feedback indexes in a training process in real time in a model training period, and obtaining a feedback index set; s2, weak item categories are analyzed and recognized based on the feedback index set, and an optimization instruction is generated; s3, dynamically adjusting the sampling weight to form an updated sampling strategy; s4, samples are collected according to a sampling strategy, and weak item category samples are supplemented; s5, putting the optimized sample set into the next round of training, and circulating the steps S1 to S4 until the training indexes of the learning effects of all key categories meet the termination condition; and acquiring a sampling strategy and a sample set. According to the method, real-time, refined and automatic sampling adjustment can be realized by taking the actual performance of model training as a core feedback index, so that the training effect and generalization ability of the model in key areas such as weak-term categories and long-tail categories are improved.

The invention discloses a method for determining the content of hydrogen ions in a chloroplatinic acid solution, and belongs to the technical field of analytical testing. In order to solve the problems that the chloroplatinic acid solution is yellow after being diluted and the manual titration end point is difficult to judge, a potentiometric titration method is adopted, and the end point is determined by measuring electrode potential mutation without depending on indicator color change. The method comprises the steps of test condition preparation, burette calibration, standard solution preparation and calibration, sample treatment and titration, result calculation and the like, a full-automatic potentiometric titrator is selected, the titration volume is controlled within the range of 10-15 mL, and a sodium hydroxide standard solution is used for sample titration after calibration. The relative standard deviation of the determination result is less than 0.5%, the adding standard recovery rate is between 96.3% and 103.1%, and the method has the characteristics of high analysis speed, high accuracy and good stability, is suitable for accurate detection of hydrogen ions in chloroplatinic acid production and quality inspection, and effectively solves the defects of the traditional method.

The invention belongs to the technical field of petroleum and natural gas exploration and development, and particularly relates to a method for multi-dimensionally analyzing a layering state of a water body of an ancient lake based on lamina features. The method comprises the steps of sample treatment, biological disturbance level grading, lamina thickness statistics, PCAS-based analysis test, lamina feature FIB-SEM three-dimensional reconstruction, lamina formation cause identification of lamina microcell elements and isotope verification, and fully combines the current advanced characterization and test technology. Qualitative and quantitative analysis evaluation is carried out on the layering state of the ancient lake water body from multiple dimensions of lamina layering performance, lamina thickness, lamina characteristics and lamina formation causes, the defect that the layering state of the water body is not accurately judged in a single dimension is overcome, and the characteristics of the internal microlayers and the spatial distribution condition of the internal microlayers are more visually displayed.

The invention provides a sample processing method and device, equipment and a storage medium, and relates to the technical field of data processing, in particular to the technical fields of artificial intelligence, big data and the like. According to the specific implementation scheme, a plurality of historical living body images are acquired; the historical living body image represents biological characteristic information of the target object; performing clustering processing on the plurality of historical living body images based on image features with biological feature information corresponding to the historical living body images to obtain a plurality of first clusters; obtaining a risk level of each first cluster based on the attribute feature information of the target object; and at least utilizing the risk level of each first cluster to construct a target sample data set.

The present invention discloses a magnetic nanocomposite material, a preparation method thereof, and an application thereof in the enrichment of low-abundance proteins. The magnetic nanocomposite material proposed by the present invention is Fe3O4@TS-1. Its preparation method is simple to operate. The sol-gel hydrothermal method is adopted, and the preparation is stable. The magnetic composite material Fe3O4@TS-1 is successfully synthesized. While ensuring the material properties of the TS-1 molecular sieve material, this material not only guarantees excellent protein adsorption performance but also endows it with magnetism, providing a simpler, faster, and more efficient technical method for large-scale sample processing. The enrichment of low-abundance proteins based on the magnetic nanocomposite material proposed by the present invention can be applied to almost all sample types, effectively solving the interference caused by high-abundance proteins to the identification of low-abundance proteins during mass spectrometry detection, and the number of protein identifications can be increased by 100% - 700%.

The embodiment of the invention discloses a biological sample storage management method and device applied to a biological sample library. A specific embodiment of the method comprises the following steps: acquiring transportation duration, a biological sample data set, transportation temperature data and transportation vibration data of a biological sample transportation vehicle; sorting the biological sample data in the biological sample data set to obtain a biological sample data sequence; performing sample activity detection on each piece of biological sample data in the biological sample data sequence to obtain a sample activity value sequence; generating a sample processing information sequence corresponding to each piece of biological sample data in the biological sample data sequence; establishing a corresponding sample processing task for each piece of biological sample data in the biological sample data sequence to obtain a sample processing task sequence; and performing corresponding sample processing operations on the corresponding biological samples in sequence, and storing the processed biological samples in a biological sample library for storage and management. According to the embodiment, the loss of the biological sample can be reduced.

The invention discloses a method for detecting the content of chlorophenol substances in a bamboo material and a product for food contact, and belongs to the technical field of detection. The method specifically comprises the steps of standard liquid preparation, sample treatment and sample testing. According to the method, a content and migration quantity pretreatment mode without derivatization treatment is adopted, and an ultra-high performance liquid chromatography-tandem mass spectrometry detection technology is matched, so that the method for testing the content of the chlorophenol substances in the bamboo and wood materials and products for food contact, which is simple in pretreatment process, accurate in test, efficient, rapid, high in sensitivity and high in practicability, is realized.

The invention provides a sample processing system capable of performing processing efficiently. As a technical means for this purpose, a sample processing system is used which comprises: an input / collection unit that includes an input mechanism for storing a plurality of glass slides on which samples to be subjected to dyeing processing, dehydration processing, sealing processing, or scanning processing are placed, and a collection mechanism for storing the processed glass slides; a dyeing unit that performs a dyeing process on the sample placed on the slide; a post-processing unit that performs a dehydration process, a sealing process, or a scanning process on the sample placed on the slide; and a transport unit capable of transporting the slide between the staining unit and the input / recovery unit and between the input / recovery unit and the post-processing unit, the staining unit, the input / recovery unit, and the post-processing unit being arranged in this order.

The invention relates to the technical field of meat quality detection, and discloses a fresh beef quality analysis system suitable for a beef jerky processing factory, which comprises a data acquisition module, a quality analysis module, a central control module, an early warning feedback module and a tracing linkage module, a sensor unit, a sample processing unit and a data preprocessing unit are integrated through a data acquisition module, and multiple physical, chemical and biological index data such as color, texture and pH value of fresh beef are acquired in real time in a non-intrusive manner by adopting a multi-source sensing technology, so that the comprehensiveness and reliability of quality analysis input are ensured; meanwhile, sample preparation and positioning are standardized through the sample processing unit, actual storage conditions of a processing plant are simulated, and the accuracy of data acquisition is improved; and a threshold value alarm unit of the early warning feedback module automatically triggers multi-level alarm according to a quality analysis result, so that real-time early warning and graded response of quality abnormal conditions are realized.

The invention relates to the technical field of shale undisturbed formation porosity determination, and discloses a shale undisturbed formation porosity determination method, which comprises: selecting a representative rock sample from a shale formation, carrying out necessary cutting and oil washing treatment on the selected rock sample, crushing the treated shale sample, and screening to obtain the shale undisturbed formation porosity. The method comprises the following steps: selecting particles with proper mesh number, and measuring the density of a shale skeleton sample under the condition of simulating formation temperature and pressure by utilizing a high-temperature and high-pressure magnetic suspension balance or other high-precision density measuring equipment. According to the method, more accurate formation porosity parameters can be obtained by directly measuring the porosity of the shale undisturbed formation, errors caused by change of a pore structure in the processes of sample treatment, transportation and the like are avoided, and the porosity condition of the shale in the formation can be reflected more truly by simulating the formation pressure condition for measurement. Errors caused by differences between experimental conditions and stratum conditions are avoided, and accuracy is improved.

The invention relates to the technical field of life science, in particular to a full-automatic nucleic acid extraction system and process, and the system comprises a complete machine frame, a sample adding and waste liquid treatment mechanism, an oscillation magnetic suction heating mechanism, a control system and a screen interaction system. The sample adding and waste liquid treatment mechanism realizes three-dimensional accurate positioning through transverse and longitudinal movement guide rails and a vertical movement assembly, comprises a large piston device and a small piston device which are connected in parallel, and can flexibly switch different volumes of pipettes and share a connector; the oscillation magnetic suction heating mechanism integrates oscillation, heating and magnetic suction functions and is matched with multi-specification suction heads and kits to complete sample treatment. According to the extraction process, all the mechanisms are linked through a control system, and full-flow operation such as sample cracking, solid-liquid separation, magnetic bead purification and elution is automatically completed. The nucleic acid extraction device realizes automation and precision of nucleic acid extraction, improves the operation efficiency and the extraction effect, and is suitable for nucleic acid extraction of samples such as plant tissues, animal tissues, blood and plasmids.

The invention provides a high-throughput detection and bioinformation analysis and identification method for a human ring virus group, the method comprises the whole process from reference database construction, sample processing, high-throughput sequencing to bioinformation analysis, and the technical scheme specifically comprises the following steps: step 1, constructing a human ring virus high-quality reference database; 2, performing high-throughput sequencing on the metagenome of the human sample; and step 3, a ring virus group biological information analysis process.

The invention provides a large model scene-oriented sample processing method, and relates to the technical field of artificial intelligence, in particular to the technical fields of large models, deep learning technologies and big data. According to the specific implementation scheme, sample evaluation results of multiple to-be-processed sample texts are determined according to multiple model output results of the multiple to-be-processed sample texts, and the multiple model output results of the to-be-processed sample texts are output by multiple deep learning models with different parameter quantities; determining at least one feature tag of each of the plurality of to-be-processed sample texts; and determining a feature evaluation value of the feature tag according to respective sample evaluation results of the plurality of to-be-processed sample texts with the same feature tag. The invention further provides a large model scene-oriented sample processing device, electronic equipment and a storage medium.

The invention relates to the technical field of mass spectrometer sampling, in particular to a sampling device of an inductively coupled plasma mass spectrometer, which comprises a bottom plate, and an inductively coupled plasma mass spectrometer body is fixedly mounted at the top of the bottom plate. During application, the sample introduction mechanism adopts a first motor to drive a turntable to carry a sample during use, power is amplified through transmission of a large belt wheel and a small belt wheel, and a non-contact magnetic coupling drives a pumping spiral driving blade to rotate to generate negative pressure, so that automatic sample extraction, negative pressure control of opening and closing of a plugging plate and accurate control of a sample conveying channel are realized; by means of the design, carrying power is converted into pumping power, the equipment structure is simplified, the number of parts and energy consumption are reduced, the equipment operation and maintenance cost is reduced, an automatic continuous sample injection process replaces traditional single-pipe extraction, the sample injection time is greatly shortened, and the sample treatment efficiency is improved.

The invention relates to the technical field of medical diagnosis, and discloses an integrated nucleic acid detection method and device based on a micro-fluidic chip, the integrated nucleic acid detection device comprises a micro-fluidic chip module, a liquid control module, a temperature control module, an optical detection module and a data processing module, and the multiple modules work cooperatively to realize full-process automatic detection of a sample from splitting decomposition to detection; the micro-fluidic chip module comprises a sample treatment area, a nucleic acid extraction and purification area, a nucleic acid amplification area, a nucleic acid detection area and a waste liquid collection area which are connected through a micro-channel, and a valve is arranged at a key node. Through a fluid control mode combining centrifugal force and air pressure driving and valve combination of non-complex micro-pump micro-valves such as the dissolvable membrane valve, the temperature sensitive valve and the capillary force flow limiting valve, full-flow fluid sequential control can be achieved without integrating a plurality of micro-pump micro-valves; the problems of complex structure, high manufacturing difficulty and high cost caused by integration of multiple micro-pumps and micro-valves of the conventional pressure-driven micro-fluidic chip are solved.