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40639 results about "Fluorescence" patented technology

Fluorescence is the emission of light by a substance that has absorbed light or other electromagnetic radiation. It is a form of luminescence. In most cases, the emitted light has a longer wavelength, and therefore lower energy, than the absorbed radiation. The most striking example of fluorescence occurs when the absorbed radiation is in the ultraviolet region of the spectrum, and thus invisible to the human eye, while the emitted light is in the visible region, which gives the fluorescent substance a distinct color that can be seen only when exposed to UV light. Fluorescent materials cease to glow nearly immediately when the radiation source stops, unlike phosphorescent materials, which continue to emit light for some time after.

Optical-based sensing devices

An optical-based sensor for detecting the presence or amount of an analyte using both indicator and reference channels. The sensor has a sensor body with a source of radiation embedded therein. Radiation emitted by the source interacts with indicator membrane indicator molecules proximate the surface of the body. At least one optical characteristic of these indicator molecules varies with analyte concentration. For example, the level of fluorescence of fluorescent indicator molecules or the amount of light absorbed by light-absorbing indicator molecules can vary as a function of analyte concentration. In addition, radiation emitted by the source also interacts with reference membrane indicator molecules proximate the surface of the body. Radiation (e.g., light) emitted or reflected by these indicator molecules enters and is internally reflected in the sensor body. Photosensitive elements within the sensor body generate both indicator channel and reference channel signals to provide an accurate indication of the concentration of the analyte. Preferred embodiments are totally self-contained and are sized and shaped for use in vivo in a human being. Such embodiments preferably include a power source, e.g. an inductor, which powers the source of radiation using external means, as well as a transmitter, e.g. an inductor, to transmit to external pickup means the signal representing the level of analyte.
Owner:SENSEONICS INC

Asynchronous fluorescence scan

The present invention is directed to asynchronous scanning devices and methods of using asynchronous scanning to acquire fluorescence data from a sample, such as biological tissue, to facilitate diagnosis of the presence or absence of disease or other abnormality in the sample. The present invention is useful for biomedical diagnostics, chemical analysis or other evaluation of the target sample.
Owner:CERCACOR LAB INC

Integrated active flux microfluidic devices and methods

InactiveUS6767706B2Rapid and complete exposureQuick and accurate and inexpensive analysisBioreactor/fermenter combinationsFlow mixersAntigenHybridization probe
The invention relates to a microfabricated device for the rapid detection of DNA, proteins or other molecules associated with a particular disease. The devices and methods of the invention can be used for the simultaneous diagnosis of multiple diseases by detecting molecules (e.g. amounts of molecules), such as polynucleotides (e.g., DNA) or proteins (e.g., antibodies), by measuring the signal of a detectable reporter associated with hybridized polynucleotides or antigen / antibody complex. In the microfabricated device according to the invention, detection of the presence of molecules (i.e., polynucleotides, proteins, or antigen / antibody complexes) are correlated to a hybridization signal from an optically-detectable (e.g. fluorescent) reporter associated with the bound molecules. These hybridization signals can be detected by any suitable means, for example optical, and can be stored for example in a computer as a representation of the presence of a particular gene. Hybridization probes can be immobilized on a substrate that forms part of or is exposed to a channel or channels of the device that form a closed loop, for circulation of sample to actively contact complementary probes. Universal chips according to the invention can be fabricated not only with DNA but also with other molecules such as RNA, proteins, peptide nucleic acid (PNA) and polyamide molecules.
Owner:CALIFORNIA INST OF TECH

LED replacement for fluorescent lighting

InactiveUS6860628B2Reduce eliminateReducing or eliminating any additional electrical componentryCoupling device connectionsLight source combinationsTransformerFluorescence
The present invention provides several embodiments of an elongate hollow tubular or solid rod lighting device including a plurality of LEDs therewith and appropriate electrical componentry, and serving as a direct replacement for a conventional fluorescent light tube in a conventional fluorescent lighting fixture. The present lighting device includes appropriate connector pins extending from each end thereof, enabling the device to be installed in a conventional fluorescent lighting fixture with no modification to the fixture. The light may include appropriate electrical componentry such as a step-down transformer to provide the required voltage for the LEDs, either integrally within the light, incorporated in an end cap thereof, or installed separately therefrom in the fixture, as desired. The light may be colored or tinted as desired by the use of LEDs providing the desired color output, and / or by installing a tinted sleeve over the tube or rod as desired.
Owner:SAMSUNG ELECTRONICS CO LTD

Retrofit LED lamp for fluorescent fixtures without ballast

An energy saving device for an LED lamp mounted to an existing fixture for a fluorescent lamp where the ballast is removed or bypassed. The LEDs are positioned within a tube and electrical power is delivered from a power source to the LEDs. The LED lamp includes means for controlling the delivery of the electrical power from the power source to the LEDs, wherein the use of electrical power can be reduced or eliminated automatically during periods of non-use. Such means for controlling includes means for detecting the level of daylight in the illumination area of said least one LED, in particular a light level photosensor, and means for transmitting to the means for controlling relating to the detected level of daylight from the photosensor. The photosensor can be used in operative association with an on-off switch in power connection to the LEDs, a timer, or with a computer or logic gate array in operative association with a switch, timer, or dimmer that regulates the power to the LEDs. An occupancy sensor that detects motion or a person in the illumination area of the LEDs can be also be used in association with the photosensor and the computer, switch, timer, or dimmer, or in solo operation by itself. Two or more such LED lamps with a computer or logic gate array used with at least one of the lamps can be in network communication with at least one photosensor and / or at least one occupancy sensor to control the power to all the LEDs.
Owner:SIGNIFY HLDG BV

Phosphor screen and displays systems

A phosphor screen for image forming including phosphor material being excitable by light in a wavelength λ1. The phosphor screen receives an optical image from an image forming optical system and produces the optical image at a second wavelength λ2. The phosphor screen includes a phosphor layer comprising the phosphor material. A short-pass reflective coating is positioned on a first side of the phosphor layer. The short-pass reflective coating transmits the wavelength λ1 and reflects the wavelength λ2. A long-pass reflective coating is positioned on a second side of the phosphor layer. The long-pass reflective coating transmits the wavelength λ2 and reflects the wavelength λ1. A first substrate is positioned over the short-pass reflective coating. The first substrate is formed of optically clear and thermal conductive material. A second substrate is positioned over the long-pass reflective coating. The second substrate is formed of long-pass absorptive optical filter material that transmits the wavelength λ2 and absorbs wavelength λ1 from ambient light to prevent the phosphor layer from being excited by the ambient light. The phosphor screen may alternatively be used for a direct-view visual display apparatus. These principles can also be utilized for backlighting and general illumination applications.
Owner:ROCKWELL COLLINS INC

Retrofit LED lamp for fluorescent fixtures without ballast

An energy saving device for an LED lamp mounted to an existing fixture for a fluorescent lamp where the ballast is removed or bypassed. The LEDs are positioned within a tube and electrical power is delivered from a power source to the LEDs. The LED lamp includes means for controlling the delivery of the electrical power from the power source to the LEDs, wherein the use of electrical power can be reduced or eliminated automatically during periods of non-use. Such means for controlling includes means for detecting the level of daylight in the illumination area of said least one LED, in particular a light level photosensor, and means for transmitting to the means for controlling relating to the detected level of daylight from the photosensor. The photosensor can be used in operative association with an on-off switch in power connection to the LEDs, a timer, or with a computer or logic gate array in operative association with a switch, timer, or dimmer that regulates the power to the LEDs. An occupancy sensor that detects motion or a person in the illumination area of the LEDs can be also be used in association with the photosensor and the computer, switch, timer, or dimmer, or in solo operation by itself. Two or more such LED lamps with a computer or logic gate array used with at least one of the lamps can be in network communication with at least one photosensor and / or at least one occupancy sensor to control the power to all the LEDs.
Owner:SIGNIFY HLDG BV

Optical-based sensing devices

An optical-based sensor for detecting the presence or amount of an analyte using both indicator and reference channels. The sensor has a sensor body with a source of radiation embedded therein. Radiation emitted by the source interacts with indicator membrane indicator molecules proximate the surface of the body. At least one optical characteristic of these indicator molecules varies with analyte concentration. For example, the level of fluorescence of fluorescent indicator molecules or the amount of light absorbed by light-absorbing indicator molecules can vary as a function of analyte concentration. In addition, radiation emitted by the source also interacts with reference membrane indicator molecules proximate the surface of the body. Radiation (e.g., light) emitted or reflected by these indicator molecules enters and is internally reflected in the sensor body. Photosensitive elements within the sensor body generate both indicator channel and reference channel signals to provide an accurate indication of the concentration of the analyte. Preferred embodiments are totally self-contained and are sized and shaped for use in vivo in a human being. Such embodiments preferably include a power source, e.g. an inductor, which powers the source of radiation using external means, as well as a transmitter, e.g. an inductor, to transmit to external pickup means the signal representing the level of analyte.
Owner:SENSEONICS INC

Fluorene-based compound and organic electroluminescent display device using the same

The present invention relates to an organic electroluminescent (OEL) compound that comprises at least one fluorene derivative and at least one carbazole derivative. The compound has good electrical properties, light emitting properties and charge transport ability, and thus is suitable as a host material suitable for fluorescent and phosphorescent dopants of all colors including red, green, blue, white, etc., and as a charge transport material. An OEL display device that uses an organic layer that includes the OEL compound has a high efficiency, a low voltage, a high luminance, and a long lifespan because it has superior current density.
Owner:SAMSUNG DISPLAY CO LTD

Electron beam exciter for use in chemical analysis in processing systems

ActiveUS20100032587A1Disparity will become so greatHigh electron energyCathode ray tubes/electron beam tubesRadiation therapyElectron sourceFluorescence
The present invention is directed to a gas line electron beam exciter, gas line electron beam excitation system and method for exciting a gas using an electron beam exciter. The electron beam exciter generally comprises a variable density electron source for generating a cloud of electrons in an electron chamber and a variable energy electron extractor for accelerating electrons from the electron chamber as an electron beam and into an effluent stream for fluorescing species in the effluent. The electron density of the electron beam is variably controlled by adjusting the excitation power applied to the variable density electron source. The electrons in the electron chamber reside at a reference electrical potential of the chamber, typically near ground electrical potential. The electron energy of the electron beam is variably controlled by adjusting an electrical potential across the variable energy electron extractor, which energizes the electrons through an extraction hole of the chamber and toward the extractor. The greater the difference in the electrical potential between the electron extractor and the electron source, the higher the energy imparted to the electrons in the electron beam. The excitation power applied to the electron source can be adjusted independently from the electron energy of the electron beam, thereby altering the electron density of the electron beam without changing the energy level of the electrons of the electron beam.
Owner:VERITY INSTR +1

Light emitting apparatus and light emitting method

A light emitting apparatus has a light emitting element with an emission wavelength in the range of 360 to 550 nm and a rare-earth element doped oxide nitride phosphor or cerium ion doped lanthanum silicon nitride phosphor. Part of light radiated from the light emitting element is wavelength-converted by the phosphor. The light emitting apparatus radiates white light generated by a mixture of the wavelength-converted light and the other part of light radiated from the light emitting element.
Owner:TOYODA GOSEI CO LTD +1

Constriction device viewable under X ray fluoroscopy

A constriction device that constricts body tissue is viewable under X ray fluoroscopy. The device includes an elongated sleeve. The sleeve includes opposed opened ends and is formed from expandable or elastic material to receive therein, when in an expanded condition, body tissue to be constricted and to constrict the body tissue therein when released from the expanded condition. At least a portion of the sleeve includes X ray opaque material rendering the device visible under X ray fluoroscopy.
Owner:GYRUS ACMI INC (D B A OLYMPUS SURGICAL TECH AMERICA)

Method and compositions for detection and enumeration of genetic variations

Many areas of biomedical research depend on the analysis of uncommon variations in individual genes or transcripts. Here we describe a method that can quantify such variation at a scale and ease heretofore unattainable. Each DNA molecule in a collection of such molecules is converted into a single particle to which thousands of copies of DNA identical in sequence to the original are bound. This population of beads then corresponds to a one-to-one representation of the starting DNA molecules. Variation within the original population of DNA molecules can then be simply assessed by counting fluorescently-labeled particles via flow cytometry. Millions of individual DNA molecules can be assessed in this fashion with standard laboratory equipment. Moreover, specific variants can be isolated by flow sorting and employed for further experimentation. This approach can be used for the identification and quantification of rare mutations as well as to study variations in gene sequences or transcripts in specific populations or tissues.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE

Sequencing by incorporation

Nucleotides and nucleotide analogs are used in various sequencing by incorporation / sequencing by synthesis methods. Nucleotide analogs comprising 3′-blocking groups are used to provide reversible chain-termination for sequencing by synthesis. Typical blocking groups include phosphate groups and carbamate groups. Fluorescent nucleotides are used to perform sequencing by synthesis with detection by incorporation of the fluorescently labeled nucleotide, optionally followed by photobleaching and intercalating dyes are used to detect addition of a non-labeled nucleotide in sequencing by synthesis with detection by intercalation. Microfluidic devices, including particle arrays, are used in the sequencing methods.
Owner:CAPLIPER LIFE SCI INC
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