222 results about "Benzoxazole" patented technology

The invention discloses a preparation method of antistatic modified chinlon filaments, and relates to the field of chinlon filaments. When the antistatic modified chinlon filament is prepared, (formylmethyl) diethyl phosphate and 1-aminopyrrole react to prepare pyrrole diethyl phosphate; reacting the hydroxylated multi-walled carbon nanotube with pyrrole diethyl phosphate to obtain a modified multi-walled carbon nanotube; the preparation method comprises the following steps: reacting 2, 2 '-bipyridine-5, 5'-dicarboxylic acid with 2-amino-5-nitrophenol, and then reducing to obtain a benzoxazole diamine monomer; then, adipic acid, 1, 5-diaminopentane and a benzoxazole diamine monomer are subjected to a reaction, and modified polyamide is prepared; uniformly mixing the modified polyamide, the modified multi-walled carbon nanotubes, pyrrole, ferric trichloride and copper chloride, and performing melt spinning to obtain the antistatic modified polyamide filament. The antistatic modified chinlon filament prepared by the invention has excellent antistatic, flame-retardant, anti-aging and mechanical properties.

The invention provides a low-smoke halogen-free flame-retardant cable material and a preparation method thereof, and belongs to the field of cable materials. The low-smoke halogen-free flame-retardant cable material is prepared from the following chemical components: 32 to 40 parts of nitrile rubber, 22 to 27 parts of natural rubber, 8 to 12 parts of benzoxazole-siloxane copolymer containing phosphate dynamic bonds, 13 to 15 parts of core-shell-sheath three-stage structure flame retardant, 4 to 6 parts of hexaphenoxy cyclotriphosphazene modified carbon nanotubes, 2 to 3 parts of europium-doped mesoporous cerium dioxide and 3 to 4 parts of nano zinc oxide. The composite material is prepared from the following components in parts by weight: 3 to 4 parts of carbon nanotube grafted montmorillonite hybrid, 2 to 3 parts of lubricant, 0.8 to 1.2 parts of cross-linking agent, 0.3 to 0.4 part of accelerant, 0.4 to 0.6 part of dicumyl peroxide and 0.1 to 0.2 part of antioxidant. Unification of high flame retardance, low smoke, excellent mechanical property and processability of the cable material is realized.

The present disclosure relates to pharmaceutical compositions suitable for oral administration, and more particularly to pharmaceutical compositions, including pharmaceutical tablet compositions, containing (2S)-N-{(1S)-1-cyano-2-[4-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-5-yl)phenyl]ethyl}-1,4-oxazepane-2-carboxamide (Compound A) or a pharmaceutically acceptable salt thereof.

The invention relates to the field of cables, and discloses a modified polyvinyl chloride composite material for cables and a preparation method thereof.The composite material comprises low-density polyethylene, polyvinyl chloride, ethylene-vinyl acetate copolymer, nitrile rubber, modified graphene oxide, modified nano calcium carbonate and auxiliaries; the modified graphene oxide is prepared by reacting acylating chlorination of graphene oxide with an anti-aging derivative, the anti-aging derivative is prepared by reducing a benzoxazole-containing intermediate generated by a reaction of 2-amino-4-bromophenol and 4-cyanobenzaldehyde to obtain an aminated benzoxazole-containing intermediate, then the aminated benzoxazole-containing intermediate reacts with p-phenylenediamine, and then the product reacts with 3-(3, 4-dichlorophenyl)-1, 2, 3-triazole-3-one to obtain the anti-aging graphene oxide. 2, 5-di-tert-butyl-4-hydroxyphenyl) propionyl chloride is subjected to a reaction to prepare the product. And the modified nano calcium carbonate is prepared by reacting phosphonitrilic chloride trimer with an amino silane coupling agent and 2-amino benzoxazole-5-borate and then grafting on the surface of the nano calcium carbonate. The composite material prepared by the invention has excellent flame retardance, heat resistance and long-acting oxidation resistance.

The invention relates to the technical field of photoelectricity, in particular to a light conversion agent based on a benzoxazole skeleton and a preparation method and application of the light conversion agent. The invention provides a light conversion agent based on a benzoxazole skeleton. The light conversion agent comprises an organic compound taking benzoxazole as a parent. According to the light conversion agent based on the benzoxazole skeleton, the problems that an existing light conversion agent is low in ultraviolet light absorption efficiency, and the photoelectric conversion efficiency of a prepared light conversion adhesive film is low are solved.

Formula (I): JPEG2025536322000043.jpg74140 (in the formula, L, R 1 , R 2 , R 3 and W is as defined in the specification. and their enantiomers, diastereomers, racemates, tautomers, prodrugs, hydrates, solvates and pharmaceutically acceptable salts are useful in the treatment of diseases and conditions affected by the inhibition of Mer kinase, such as cancer.

The preparation method comprises the following steps: taking para aminobenzoic acid, 3, 3-diaminobiphenyl and phosphorus pentoxide as raw materials, and carrying out high-temperature dehydration cyclization reaction in a polyphosphoric acid solvent to obtain a diamine monomer containing biimidazole; the preparation method comprises the following steps: adding a bis-imidazole-containing diamine monomer, 2-(4-aminophenyl)-5-aminobenzoxazole and an organic solvent into a reactor, stirring and dissolving, after the solution is clarified, adding pyromellitic dianhydride, stirring and reacting, and after the reaction is completed, obtaining a polyamide acid membrane casting solution; and carrying out film casting on the polyamide acid film casting solution, drying at low temperature, and transferring to a muffle furnace to carry out imidization reaction after solvent volatilization is finished, so as to obtain the bis-imidazole polyimide film. The biimidazole polyimide film constructed by the invention is applied to a flexible OLED substrate, and has relatively good thermal performance and mechanical performance.

The present application provides a compound containing hydroxyl triarylamine, which can be used as a light extraction material, and its structure is shown in formula (I). In formula (I), hydroxyl groups and benzoxazole or benzothiazole are introduced into the triarylamine main structure of the traditional light extraction layer material. The hydrogen atoms in the hydroxyl group can form intramolecular hydrogen bonds with the heteroatoms on benzoxazole or benzothiazole, thereby improving the planarity of the molecule and increasing the packing density between molecules. At the same time, this intramolecular hydrogen bond undergoes intramolecular proton transfer under light conditions to form a resonance structure. This process converts ultraviolet light energy into heat energy release instead of material deterioration caused by photochemical reactions, thereby reducing the damage caused by ultraviolet light to the device. In addition, the raw materials of the compound are easy to obtain, and it has higher economic value while ensuring good device protection function. The present application also provides an organic electroluminescent device and a display device. #imgabs0#

The invention discloses an iron-loaded sulfonated carbon nitride heterogeneous catalyst as well as a preparation method and application thereof, and belongs to the field of heterogeneous catalysts. The iron-loaded sulfonated carbon nitride heterogeneous catalyst consists of monatomic Fe and a sulfonated graphite phase carbon nitride carrier, so that the prepared iron-loaded sulfonated carbon nitride heterogeneous catalyst can catalyze the reaction of benzoxazole and absolute ethyl alcohol, is high in catalytic efficiency, can catalyze the reaction of benzimidazole or benzothiazole and absolute ethyl alcohol, and is high in catalytic efficiency. Therefore, 2-(1-hydroxyethyl)-benzimidazole or 2-(1-hydroxyethyl)-benzothiazole is synthesized, and concentrated acid does not need to be used as a catalyst in the synthesis process. The sulfonation degree of the iron-loaded sulfonated carbon nitride heterogeneous catalyst can be regulated and controlled, the iron-loaded sulfonated carbon nitride heterogeneous catalyst can catalyze the construction of a directional C-C bond, and the iron-loaded sulfonated carbon nitride heterogeneous catalyst keeps stable in the reaction process and can be recycled for 5 times or more.

The invention belongs to the field of chemical synthesis of pesticides, and discloses a preparation method of a benzoxazole intermediate, which comprises the following steps: (1) carrying out substitution reaction on a compound with a structure as shown in a formula III to obtain a compound with a structure as shown in a formula IV; (2) carrying out oxidation reaction on the compound with the structure as shown in the formula IV prepared in the step (1) to obtain a benzoxazole intermediate with a structure as shown in a formula V; # imgabs0 #

The invention relates to an organic compound, a composition and an organic electronic device. The organic compound has a structural formula as shown in formula (1): # imgabs0 # (1); large groups, such as naphthyl benzothiazole, naphthyl phenyl benzothiazole group and at least one phenyl benzoxazole or phenyl benzothiazole group, are added into the organic compound, so that the glass transition temperature of the organic compound is increased, the thermal stability of the organic compound is improved, and the organic compound has a good application prospect. The extinction coefficient of the organic compound in an ultraviolet band is high, the extinction coefficient of the organic compound in a visible light range is small, and the organic compound has a high refractive index; when the organic compound provided by the invention is used as a light extraction layer material of an organic electronic device, adverse effects of harmful light on internal materials of the device can be avoided, and the light extraction efficiency of visible light can be improved.

The invention discloses light-cured resin, a preparation method and application, and belongs to the technical field of light-cured 3D printing. The light-cured resin provided by the invention comprises an acrylate oligomer, a reactive diluent, polyfunctional mercaptan, a polymerization inhibitor, a benzoxazole absorbent and an ultraviolet light absorber, the acrylate oligomer and the reactive diluent are main bodies of the light-cured resin, and the polyfunctional mercaptan and the polymerization inhibitor are added on the basis of the main bodies of the light-cured resin, so that the light-cured resin is prepared. The curing rate can be improved, the reaction speed under low energy is inhibited, the curing degree is improved, the curing thickness is reduced, and the printing precision can be improved. Moreover, by adding the benzoxazole absorbent and the ultraviolet absorbent, the curing thickness can be reduced, and all the components play a synergistic effect, so that the printing precision is improved.

The present invention discloses a fluorescent probe and a fluorescent label for real-time non-destructive visualization monitoring of the freshness of meat food, and their preparation methods and applications. The structural formula of the fluorescent probe HBT-Bz is simple and easy to synthesize. Using the HBT fluorophore with ESIPT properties and AIE effect as the parent body and benzoxazole ester group as the recognition group for amine compounds, a fluorescence turn-on probe is designed and synthesized. The fluorescent probe HBT-Bz responds quickly and sensitively to amine compounds, with a detection limit as low as 5.1 ppm, and can be used to fabricate a solid fluorescence sensor for detecting volatile amine compounds. The synthetic route of the fluorescent probe involved in the present invention is simple, can recognize a variety of volatile amines, has a low detection limit, and the preparation process of the fluorescent label loaded with the fluorescent probe is simple. When in use, no pretreatment of the food is required. Placing the fluorescent label in the meat food packaging can realize real-time non-destructive visualization monitoring of the food freshness, and the results are accurate and reliable.

The application relates to a quality inspection technology of inorganic salt, and discloses a detection reagent and a rapid detection method for high-purity lithium carbonate. A water-soluble fluorescent probe detection reagent is obtained by using 2-(4-chlorophenyl) benzoxazole, 2-(2-hydroxyphenyl) benzoxazole and other benzoxazole compounds as a substrate, and by modifying the substrate with glycerol, tris(hydroxyl) aminomethane and other compounds; high-purity lithium carbonate is detected by using the detection reagent; the high-purity lithium carbonate is solid-phase prepared into lithium carbonate suspension liquid; the upper liquid phase of the lithium carbonate suspension liquid is taken; the fluorescent probe detection reagent is added into the upper liquid phase; and the high-purity lithium carbonate is rapidly detected according to the fluorescent spectrum and a working curve. The application can realize the rapid detection of the high-purity lithium carbonate in a water-soluble environment, and the detection response time can be as short as 3-10 seconds.

The disclosure relates to compounds of Formula I or a pharmaceutically acceptable salt thereof, wherein, m, R1-R5, R5A, and L are defined herein. These compounds are useful in methods for stabilizing a mutant PAH protein or reducing blood phenylalanine concentration in a subject suffering from phenylketonuria. In some embodiments, the mutant PAH protein contains at least one R408W, R261Q, R243Q, Y414C, L48S, A403V, I65T, R241C, L348V, R408Q, or V388M mutation. In other embodiments, the mutant PAH protein contains at least one R408W, Y414C, I65T, F39L, R408Q, L348V, R261Q, A300S, or L48S mutation.

The invention relates to a benzoxazole derivative containing a dithioacetal unit as well as a preparation method and application of the benzoxazole derivative. The compound disclosed by the invention has excellent antiviral activity on cucumber green mottle mosaic virus and the like, and can be used for medicines or medicaments for preventing and treating plant virus diseases such as cucumber green mottle mosaic disease and the like. The structure and the preparation process are simple, and the production cost is low; the benzoxazole derivative containing the dithioacetal unit comprises a benzoxazole compound with the dithioacetal unit, or a stereoisomer of the benzoxazole compound, or a salt of the benzoxazole compound or a solvate of the benzoxazole compound. Structural formula of benzoxazole compound with dithioacetal unit is as follows: # imgabs0 #

The invention relates to the technical field of waterproof coiled materials, in particular to an anti-ultraviolet SBS waterproof coiled material and a preparation method thereof.The waterproof coiled material comprises a base layer, an anti-ultraviolet SBS asphalt layer and a thin film layer, the anti-ultraviolet SBS asphalt layer comprises asphalt, an SBS elastomer, asphalt softening oil, an anti-aging waterproof multifunctional agent, composite filler, an initiator and the like, and the thin film layer is prepared from the following components; the anti-aging waterproof multifunctional agent prepared by the invention takes macromolecular polysiloxane as a main chain and simultaneously contains a double hindered amine structure and a benzoxazole structure, and the benzoxazole structure not only can cooperate with a polysiloxane structure to improve the thermal aging resistance of a material, but also can endow a coiled material with a rigid structure; the double hindered amine structure has better ultraviolet aging resistance and does not influence the improvement of silicon-oxygen bonds on the waterproof performance of the coiled material, and the functional agent can make the asphalt coiled material become a coiled material resistant to thermal aging, ultraviolet aging and chemical substance erosion.

The invention discloses a preparation method and application of a covalent organic framework material containing imine bonds and benzoxazole rings in different proportions. The preparation method comprises the following steps: by taking amido and aldehyde group as construction units, adjusting the feeding proportion of a third monomer, quickly freezing in a liquid nitrogen bath, carrying out freezing-unfreezing circulating degassing, reacting in a water-free and oxygen-free environment, and after the reaction, filtering and cleaning, Soxhlet extraction, washing and freeze-drying to obtain the covalent organic framework material. Wherein different molecular construction units are beneficial to regulating and controlling the adsorption strength of an oxygen intermediate in an electrochemical process, so that an energy barrier in an electro-catalysis OER process is changed, and the catalytic activity of an electro-catalyst is improved. The preparation method is simple and has potential application prospects in the field of electrochemical catalysis.

The present invention relates to a composition in the form of a water-in-oil emulsion, comprising: a) at least one oily continuous phase comprising at least one volatile oil chosen from volatile hydrocarbon oils, volatile silicone oils and their mixtures, and b) at least one aqueous phase dispersed in said oily phase, the amount of water being greater than or equal to 20% by weight, with respect to the total weight of the composition, and c) at least one hydrophobic film-forming polymer, and d) at least one emulsifying surfactant chosen from polyoxyalkylenated linear polydimethylmethylsiloxanes with an HLB ≤ 8.0, and e) at least 3.0% by weight of a vitamin B3 and / or one of its derivatives, with respect to the total weight of the composition, said composition not containing a water-soluble organic UV screening agent comprising at least one benzylidenecamphorsulfonic acid group nor a water-soluble organic UV screening agent comprising at least one benzoxazolesulfonic acid group.

Semiconductor device packages are provided. The semiconductor device package comprises a first structure having a first surface in the semiconductor device package, a second structure having a second surface in the semiconductor device package, and an adhesion promoting layer in contact with the first surface on a first side and the second surface on a second side. The adhesion promoting layer comprises a polyimide containing repeating units derived from a tetracarboxylic dianhydride and at least one diamine containing a functional group, wherein a diamine benzoxazole or a diamine benzimidazole are preferred, and a combination of a diamine benzoxazole and a diamine benzimidazole is particularly preferred.

A novel method for artificial photosynthesis utilizing a chemical system that operates by harnessing visible light and directly capturing carbon dioxide and water from the atmosphere. The system is based on self-organizing complexes comprising visible-light-sensitive chromophores, such as 2-phenyl indole and 2-phenyl benzoxazole, along with titanium tetrachloride, which autonomously perform continuous, complex chemical operations to produce long-chain (C2 to C17) oxygenated organic materials. The process employs earth-abundant metal coordination compounds, including titanium (Ti), zirconium (Zr), hafnium (Hf), and vanadium (V), in the solid state. These compounds form carbonated metal derivatives upon hydrolysis, which are subsequently reduced through proton transfer from water. The system initially generates C1 materials that oligomerize via a novel self-catalyzed mechanism intrinsic to the system's operation. Monitoring and characterization of the chemical transformations have been conducted using high-resolution MALDI-TOF (matrix-assisted laser desorption ionization-time of flight) mass spectrometry, supported by infrared (IR) spectroscopy and nuclear magnetic resonance (NMR) analysis. This innovation represents a sustainable and scalable approach for converting atmospheric CO2 into valuable organic materials.

The invention relates to a preparation method of suvorexant, which comprises the following steps: (1) dissolving a compound VIII (R)-4-(5-chlorobenzo [d] oxazole-2-yl)-7-methyl-1, 4-diazacycloheptane-1-carboxylic acid tert-butyl ester in a reaction solvent, adding an acidic reagent at the temperature of 5-15 DEG C, and reacting at the temperature of 25-35 DEG C to prepare a compound IX (R)-5-chloro-2-(5-methyl-1, 4-diazacycloheptane-1-carboxylic acid tert-butyl ester; 2, 4-diazacycloheptane-1-yl) benzo [d] oxazole is used as a raw material; and (2) in an alkaline environment and an aprotic solvent, carrying out acylation nucleophilic reaction on the compound IX and 5-methyl-2-(2H-1, 2, 3-triazole-2-yl) benzoic acid to obtain the suvorexant. According to the preparation method, the obtained product is high in yield, the purity reaches 99.9% or above, and the intermediate product is good in character, few in impurity and suitable for industrial production.

The invention discloses a cis-hydrogen benzofuran compound with a novel structure and a preparation method thereof, and belongs to the technical field of organic synthesis.A benzoxazole-pyridine complex of palladium is used as a catalyst, an alkynyl cyclohexadienone compound and a carboxylic acid compound are used as substrates, and the cis-hydrogen benzofuran compound is prepared through a one-step reaction. According to the invention, different ligands are selected to realize the series cyclization reactions with completely different reaction paths, and the cis-hydrogen benzofuran compound with the novel structure is obtained at high yield. The method has the advantages of wide substrate range, simple and easy operation, mild reaction conditions, low energy consumption, environmental friendliness and good yield.

Disclosed are a crystal of the compound (S)—N—((S)-1-cyano-2-(2-fluoro-4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)ethyl)-1,4-oxazacycloheptane-2-carboxamide salt or a salt thereof, a preparation method therefor, and the uses thereof in pharmaceutical compositions and in medicine.

Disclosed are a crystal of the compound (S)-N-((S)-1-cyano-2-(2-fluoro-4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)ethyl)-1,4-oxazacycloheptane-2-carboxamide salt or a salt thereof, a preparation method therefor, and the uses thereof in pharmaceutical compositions and in medicine.

The invention relates to a rectification system for preparing 2-(4-methylphenyl) benzoxazole, and relates to the technical field of rectification. A wall scraping stirring device is additionally arranged in a cone of a rectification kettle, a hydraulic driving scraper is arranged in the cone, static deposition of residues is effectively broken, local overheating scaling is avoided, the uniformity of the residues is improved through forced stirring, and the overall viscosity is reduced; residues attached to the kettle wall can be scraped, and wall sticking and caking are prevented; a kettle bottom auxiliary temperature control system is additionally arranged, high-temperature heat-conducting oil is introduced into a jacket structure of the rectifying kettle, the cone temperature is maintained, accurate control is conducted through an independent temperature controller, it is ensured that the residue temperature is stable, residue carbonization caused by local overheating is prevented, it is ensured that the kettle bottom residue temperature is above a softening flow threshold value, the residue viscosity is reduced, and cooling caking is avoided; in cooperation with the rectifying still, still bottom residues in the cone of the rectifying still are effectively cleaned, continuous and stable operation of a rectifying system is ensured, and the stopping time caused by residue blockage is shortened.

The application discloses a preparation method of a 2-substituted benzoxazole compound, which comprises the following steps: first, a hydroxyphenyl glycine derivative and a Lewis acid are added into an organic solvent according to a molar ratio of 1:0.2, visible light is used for irradiation, stirring is conducted in air at room temperature until a sufficient reaction is achieved, the organic solvent is removed by using reduced pressure distillation, and then column chromatography is adopted to obtain a 2-substituted benzoxazole derivative. The application has the advantages of mild reaction conditions, greenness, low cost and high efficiency.

The present application aims at preventing deterioration inside an organic EL element, greatly improving light extraction efficiency, and providing a compound that absorbs light of wavelengths of 400 nm to 410 nm of sunlight without affecting materials inside the element, and has a high refractive index in the range of wavelengths of 450 nm to 750 nm. The present application is an amine compound that has a high refractive index and a specific benzoxazole ring structure. In an organic EL element having, in at least this order, an anode electrode, a hole transporting layer, a light emitting layer, an electron transporting layer, a cathode electrode, and a cover layer, the cover layer preferably contains the amine compound of the present application that has a specific benzoxazole ring structure.