The invention discloses a high-low temperature and oil-resistant cable, which comprises a wire, a high-temperature-resistant insulating layer covering the wire, a shielding layer covering the high-temperature-resistant insulating layer, and a protective layer covering the shielding layer; Parts include: EPDM rubber 60-80, silicone rubber 20-40, modified sepiolite 15-25, modified silica 15-25, ferric oxide 1-3, tributyl citrate 15 -25, epoxy soybean oil 20-30, microencapsulated red phosphorus 10-20, nano magnesium hydroxide 10-30, Si69 0.5-2.5, sulfur 1-2, dicumyl peroxide 0.5-1, isocyanide Triallyl Urate 0.5-0.8, Stearic Acid 0.2-0.5, Zinc Oxide 0.2-0.4, Dibutyltin Oxide 2-3, Rare Earth Stabilizer 1-2, Antiaging Agent 264 0.1-0.3, Antiaging Agent 4010 0.2- 0.4, paraffin 3-5.