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892 results about "Propylene glycol" patented technology

Propylene glycol (IUPAC name: propane-1,2-diol) is an organic compound with the chemical formula CH₃CH(OH)CH₂OH. It is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Containing two alcohol groups, it is classed as a diol. It is miscible with a broad range of solvents, including water, acetone, and chloroform. In general, glycols are non-irritating, have very low volatility and very low toxicity.

Minoxidil film coating agent as well as preparation method and application thereof

The invention relates to the technical field of pharmaceutical preparations, and provides a minoxidil film coating agent as well as a preparation method and application thereof. The minoxidil film coating agent provided by the invention comprises 40-60% of propylene glycol, 3-7% of polyvinyl alcohol, 20-30% of ethanol, 1-7% of minoxidil and the balance of water. According to the invention, propylene glycol is taken as a solvent, a plasticizer and a transdermal absorption enhancer, polyvinyl alcohol is taken as a film-forming material, and ethanol is taken as a volatile agent, after administration, ethanol is volatilized to promote film formation of polyvinyl alcohol, and propylene glycol enhances the plasticity of the formed film, so that the effect of reducing liquid medicine loss is achieved, the local medicine concentration is increased, and the bioavailability is improved. The minoxidil liniment disclosed by the invention has excellent skin permeability, can effectively convey a medicine to a required part, and can ensure that the medicine is released at a fixed position of the skin and is accurately administered in a medicine release process, so that the stimulation of liquid medicine flow to other parts is reduced, and a good treatment effect is achieved.
Owner:SHANDONG INOMIC INST OF PHARM RES CO LTD

Tooth whitening composition and preparation method thereof

The invention belongs to the technical field of medical materials, and particularly relates to a tooth whitening composition and a preparation method thereof, the tooth whitening composition comprises the following components by weight: 5%-15% of hydrogen peroxide, 0.5%-1.5% of a gel matrix, 0.2%-1.0% of a thickener, 5%-10% of a humectant, 3%-8% of propylene glycol, 0.05%-0.2% of a chelating agent, 1%-3% of a sweetener, 0.1%-0.5% of sodium fluoride, and the balance of water. Aiming at the problems that an existing tooth whitening product is relatively low in pH value (most of 4.0-5.0), easy to irritate gingiva and sensitive in tooth manufacturing, and the existing tooth whitening product needs to be stored in a dark place at a low temperature and is short in whitening validity period, the pH value of the product is adjusted to 5.5-6.5, so that the product is close to oral saliva, the irritation can be reduced, the stability of the product can be ensured, the product is not easy to decompose, and the tooth whitening effect is good. Active ingredients are prevented from losing efficacy in advance, and the whitening validity period is prolonged.
Owner:XILING (ZHENJIANG) MEDICAL TECH CO LTD +1

Unsaturated polyester resin for reinforced core of optical cable and preparation method of unsaturated polyester resin

The invention discloses unsaturated polyester resin for an optical cable reinforcing core and a preparation method thereof, and belongs to the technical field of unsaturated polyester resin. The composition is composed of the following components: PG, IPA, a catalyst, maleic anhydride, AA, styrene, an antioxidant, a first polymerization inhibitor, a second polymerization inhibitor and a third polymerization inhibitor. The ratio of alcohol to acid is (1.08-1.12): 1; the activity is (3.4-3.8): 1; the molar ratio of AA to IPA is 1: (12-16); the preparation method comprises the following steps: 1) uniformly mixing propylene glycol, a catalyst and isophthalic acid; 2) raising the temperature, preserving the heat and raising the temperature again; cooling, sequentially adding a first polymerization inhibitor, maleic anhydride and adipic acid, heating, keeping the temperature, and heating again; 3) cooling and adding a second polymerization inhibitor, and 4) cooling and adding styrene, a third polymerization inhibitor and an antioxidant, uniformly mixing, and cooling to less than or equal to 60 DEG C to obtain the unsaturated polyester resin for the optical cable reinforcing core. The unsaturated polyester resin for the optical cable reinforcing core has the characteristics of high bending strength and high temperature resistance.
Owner:HUBEI WANGLIN NEW MATERIAL TECH +2

Micro-expansion anti-crack waterproof composite deep groove filler and preparation method thereof

The invention belongs to the technical field of building materials, and particularly relates to a micro-expansion anti-cracking waterproof composite deep groove filler and a preparation method thereof. The micro-bulking anti-cracking waterproof composite deep groove filler provided by the invention comprises cement, gypsum, mineral powder, nano silicon oxide, coarse aggregate, fine aggregate, modified fibers, an expanding agent, a polycarboxylate superplasticizer and water. According to the invention, polyacrylamide, calcium sulphoaluminate and magnesium oxide are adopted to jointly form an expanding agent, and early-stage-late-stage full-period shrinkage compensation is jointly formed in a concrete hydration process, so that the density of the concrete is effectively improved, and the waterproof performance of the concrete is further improved; according to the invention, sodium dodecyl benzene sulfonate and propylene glycol block polyether are adopted to carry out compound modification on graphene oxide, and gamma-aminopropyltriethoxysilane is connected to the surface of basalt fiber, so that the bonding strength of basalt fiber and a cement matrix and the compactness of the cement matrix are improved, and the waterproof and anti-cracking properties of concrete are further improved.
Owner:SHAANXI TIANSHI IND CO LTD

A viscosity reducer for thick oil with colloid as main viscosity contribution component and a preparation method thereof

The application discloses a thickened oil viscosity reducer for a main viscosity contribution component of colloid and a preparation method thereof. The thickened oil viscosity reducer comprises the following components in percentage by weight: diethylene glycol methyl ether 25-35%, propylene glycol formate 15-25%, dispersant 5-8%, chelating agent 2-4%, anti-coking agent 0.5-1%, anti-swelling agent 1-2% and corrosion inhibitor 1-2%; and the balance is water. The application is a polar + non-aromatic hydrocarbon solvent system; completely avoids high-risk substances such as nonylphenol polyoxyethylene ether, petroleum sulfonate sodium and organic chlorine; is designed in pertinence and can effectively inhibit metal-induced asphaltene bridging; can withstand working conditions from normal temperature to 250 DEG C and up to 300 DEG C; thermal stability is significantly enhanced, and residual carbon after aging is lower than 8%; viscosity reduction efficiency is higher; the system is more stable, flexible in compounding and suitable for field construction.
Owner:KARAMAY GUOKAN PETROLEUM TECH CO LTD

Capsule used as aerosol generating substrate and aerosol generating product

The invention provides a capsule used as an aerosol generating substrate, the capsule contains fuming materials propylene glycol and glycerol, a capsule skin comprises a colloidal substance, the colloidal substance is at least one of animal glue, vegetable glue, starch and a starch modifier, and only one layer of capsule skin is provided. The invention also discloses an aerosol generating product using the capsule, and uniform and sufficient smoke release can be obtained at a lower heating temperature, so that the aerosol product can further reduce the energy consumption, reduce the release of harmful substances and improve the feeling of a smoker.
Owner:SHENZHEN HUABAO COLLABORATIVE INNOVATION TECH RES INST CO LTD

High-temperature-resistant flame-retardant CPVC power cable protection pipe and preparation method thereof

The invention discloses a high-temperature-resistant flame-retardant CPVC power cable protection pipe and a preparation method thereof, and relates to the technical field of cable protection pipes. The high-temperature-resistant flame-retardant CPVC power cable protection pipe at least comprises the following raw materials in parts by mass: 100 parts of chlorinated polyvinyl chloride; 15 to 25 parts of high impact resistance type MCS resin; 8 to 12 parts of poly (1, 2-propylene glycol adipate); 12 to 20 parts of a sepiolite-methyl methacrylate-butyl acrylate compound; 8-15 parts of aluminum-titanium composite coupling agent modified magnesium-aluminum-lanthanum hydrotalcite; 3-6 parts of a rare earth composite heat stabilizer; 2-4 parts of a processing aid; 0.5 to 1.5 parts of an antioxidant; and 1-2 parts of a lubricant. The prepared high-temperature-resistant flame-retardant CPVC power cable protection pipe has high heat resistance, high flame retardance and high impact resistance, and is excellent in comprehensive performance, high in safety and reliability and long in service life.
Owner:ZHEJIANG FEILONG PIPE

Sulfate-erosion-resistant metakaolin-slag-based geopolymer concrete and preparation method thereof

The invention discloses sulfate-erosion-resistant metakaolin-slag-based geopolymer concrete, belongs to the technical field of concrete, and aims to solve the problems that the corrosion resistance of traditional silicate concrete is ineffective and the adaptability of conventional alkali-activated concrete is insufficient in a special environment. The concrete comprises the following components in parts by weight: 60-90 parts of a cementing material, 120-170 parts of aggregate, 15-30 parts of a composite activator, 2-8 parts of a function regulator and the like, the cementing material is prepared from nano TiO2 / KH-550 composite modified metakaolin, slag and silica fume-coal gangue powder-HAP composite powder; the aggregate comprises modified limestone macadam (soaked and dried by a sodium dihydrogen phosphate solution) and river sand; the composite exciting agent comprises water glass, sodium hydroxide, sodium pyrophosphate, propylene glycol and the like; the function regulator comprises superfine fly ash, a naphthalene water reducer, HPMC (Hydroxy Propyl Methyl Cellulose) and boric acid. Through the synergistic effect of the components, the sulfate corrosion resistance, the mechanical property and the environmental adaptation performance of the concrete are improved, and the concrete is suitable for engineering construction under the service environment of high-concentration sulfate and the like.
Owner:绵竹市铸诚混凝土有限公司

Solid ultrasonic gel patch as well as preparation method and application thereof

The invention discloses a solid ultrasonic gel patch as well as a preparation method and application thereof, and belongs to the technical field of medical chemistry. The solid ultrasonic gel patch is prepared from an acrylamide monomer, polyvinyl alcohol, sodium polyacrylate, sodium carboxymethyl cellulose, nano silicon dioxide, propylene glycol, glycerol, acrylic acid, triethanolamine, a cross-linking agent, an initiator and water according to a specific ratio. The prepared solid ultrasonic gel patch is highly matched with human soft tissue in acoustic impedance (about 1.62-1.63 * 10 < 6 > Pa.s / m), low in acoustic attenuation coefficient (less than or equal to 0.034 dB / (cm.MHz)), moderate in skin adhesion, excellent in flexibility and moisture retention, capable of solving the problems that a traditional ultrasonic coupling agent is inconvenient to use, easy to dry, poor in experience and the like, and suitable for acoustic wave conduction in ultrasonic examination and treatment.
Owner:SICHUAN TAIYOU TECH CO LTD

Packaged lubricated condom

The present invention relates to a packaged condom comprising a sealed package; and within the package, a condom comprising natural rubber latex and / or synthetic polyisoprene; wherein the condom comprises, on one or more surfaces thereof and in contact with the natural rubber latex and / or synthetic polyisoprene, an aqueous lubricant; wherein the aqueous lubricant comprises: a thickener and 5 wt.% to 30 wt.%, based on the total weight of the aqueous lubricant, of a humectant comprising at least one organic compound selected from the group consisting of glycerol, propylene glycol, polyethylene glycol, and any combination thereof; and one or more sugar alcohols having a molecular weight of from 120 to 10000 g / mol. It also relates to a method for preparing a packaged condom and to the use of an aqueous lubricant to lubricate one or more surfaces of a condom. The condom preferably presents a transparent appearance to the end user.
Owner:RECKITT BENCKISER HEALTH LTD

Novel compound rapid surface anesthetic and preparation method thereof

The invention discloses a novel compound rapid surface anesthetic and a preparation method thereof, and belongs to the field of pharmaceutical preparations. According to the anesthetic, core anesthetic components of lidocaine and tetracaine are compounded with propylene glycol-laurocapram synergistic penetration enhancer, menthol auxiliary penetration enhancer, carbomer 980 gel matrix, triethanolamine pH regulator, glycerol humectant, panthenol soothing agent, purified water and the like, a surface smearing agent is prepared through a specific process, and the anesthetic can be administered in combination with an iontophoresis technology. Compared with the existing surface anesthetic for the cosmetic surgery, the surface anesthetic disclosed by the invention solves the problems of slow effect taking and poor effect, can realize rapid penetration of local skin, has short anesthesia effect taking time, long duration and good effect, has no obvious irritation to the skin, has good product stability, can effectively reduce the drug toxicity, and has a good application prospect. The device is suitable for surface anesthesia of non-surgical medical beauty items such as skin beauty, laser treatment and water-light micro-needles.
Owner:AFFILIATED RENHE HOSPITAL OF CHINA THREE GORGES UNIV

Tear-resistant high-barrier biodegradable mulching film and preparation method thereof

The invention relates to the technical field of biodegradable high polymer materials, in particular to a tear-resistant high-barrier biodegradable mulching film and a preparation method thereof, and the tear-resistant high-barrier biodegradable mulching film is prepared from the following raw materials in parts by weight: 60-90 parts of poly (butylene adipate-co-terephthalate); 10 to 40 parts of poly (propylene carbonate); 0.5-5 parts of a plasticizer; 0.05 to 0.3 part of a cross-linking agent; 0.1 to 10 parts of talcum powder; 0.1 to 2 parts of a lubricant; 0.1-1 part of an anti-blocking agent; 0.1 to 1 part of an antioxidant; 0.1 to 1 part of an anti-ultraviolet agent; 0.1-1 part of a light stabilizer; 0.1 to 1 part of an anti-hydrolysis agent; 0.1-1 part of a nucleating agent; the plasticizer is poly (1, 2-propylene glycol adipate); and the cross-linking agent is 1, 4-bis (tert-butylperoxy) diisopropyl benzene. The film has good mechanical properties and water vapor transmission amount, can be completely biodegraded, and has good aging resistance.
Owner:CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES

Environment-friendly anti-icing and deicing coating as well as preparation method and application thereof

The invention discloses an environment-friendly anti-icing and deicing coating as well as a preparation method and application thereof, and aims to solve the problems of low efficiency, high corrosivity, serious environmental pollution and the like in the traditional anti-icing and deicing technology. The coating material is prepared from the following components: deionized water, polyvinylpyrrolidone, propylene glycol, glycerol, fumed silica, granular silica, ethanol, potassium acetate and a waterborne polyurethane coating. The invention further provides a preparation method of the coating material, and the coating material is applied to anti-icing of metal and plastic substrates and has dual functions of preventing icing and rapidly removing ice. The coating has the advantages of being good in durability, environmentally friendly, free of corrosion to base materials and the like, is particularly suitable for anti-icing protection of equipment such as rails, wind power blades and cables, remarkably improves the operation and maintenance efficiency of key facilities and equipment, reduces the maintenance cost and has important economic and social benefits.
Owner:UNIV OF SCI & TECH OF CHINA

High-efficiency cross color prevention composition and application thereof

PendingCN121930925AOrganic detergent compounding agentsDye stain/transfer inhibiting compositionsMethacrylateFiber
The invention relates to an efficient cross color prevention composition and application thereof, and belongs to the technical field of cross color prevention of textiles. The invention provides a cross color prevention composition. The cross color prevention composition is prepared from the following components in parts by weight: 0.5-50 parts of methoxy polyethylene glycol-500-methacrylate; 5 to 60 parts of a vinyl imidazole / vinyl pyrrolidone copolymer; and 30 to 90 parts of propylene glycol. The fiber film-forming characteristic of the methoxy polyethylene glycol-500-methacrylate is cooperated with the adsorption capacity of the vinyl imidazole / vinyl pyrrolidone copolymer, so that the cross color prevention efficiency of the detergent is remarkably improved, and the pigment residue is reduced.
Owner:ENIWAY (GUANGZHOU) TECH CO LTD +1

Children liquid milk and sterilization and preparation method thereof

The invention relates to the technical field of dairy products, in particular to liquid milk for children and a sterilization and preparation method thereof. When the liquid milk for children is prepared, the pressure of the dynamic ultrahigh-pressure microjet is 150-200MPa, the holding time is 12-15s, an emulsifier used in the liquid milk for children comprises mono-and diglycerol fatty acid ester, polyglycerol fatty acid ester and propylene glycol fatty acid ester, and the emulsifier accounts for 0.06-0.12% of the liquid milk for children by mass. The liquid milk obtained by adopting the compound emulsifier and the microjet treatment condition provided by the invention is uniform in color and luster; the tissue state is a uniform fluid, and the phenomena of precipitation, clots, impurities, viscosity and thickness are avoided; the beverage has the fragrance of cow milk, is delicious and sweet in taste, and does not have any other abnormal taste.
Owner:INNER MONGOLIA MENGNIU DAIRY IND (GROUP) CO LTD +1

Microorganism as well as application and method thereof in preparation of 1, 3-propylene glycol and / or lactic acid

The invention provides a microorganism as well as an application and a method of the microorganism in preparation of 1, 3-propylene glycol and lactic acid, the microorganism is lactobacillus reuteri, the microorganism is preserved in Guangdong Microbial Culture Collection Center on May 29, 2024, and the preservation number is GDMCC NO: 64700. The invention further provides a method for preparing 1, 3-propylene glycol and lactic acid, and the microorganism is lactobacillus reuteri and is preserved in Guangdong Microbial Culture Collection Center on May 29, 2024. The Lactobacillus reuteri can co-produce 1, 3-propylene glycol and lactic acid, has the advantages of high yield of 1, 3-propylene glycol and lactic acid, fast growth and metabolism, strong stability, high safety and the like, provides a new idea for green, low-cost and efficient production of 1, 3-propylene glycol and lactic acid, and has a wide application prospect.
Owner:GUANGZHOU TINCI MATERIALS TECH

Stable-structure Karst catalyst for synthesis of silane modified polyether

The invention relates to the field of Karstedt catalysts, and discloses a stable-structure Karstedt catalyst for silane modified polyether synthesis, and the stable-structure Karstedt catalyst is prepared from the following raw materials in parts by weight: 2-4 parts of a Karstedt catalyst, 5-8 parts of a polyether siloxane block copolymer, 1-3 parts of nano silicon dioxide, 0.5-1.5 parts of triphenylphosphine, 20-25 parts of propylene glycol monomethyl ether and 0.5-1.0 part of an organosiloxane coupling agent. A polyether siloxane block copolymer is introduced into a Karstedt Catalyst system, and a flexible coating layer is formed outside a catalytic center by utilizing molecular compatibility of a silicon-oxygen chain segment of the polyether siloxane block copolymer and a platinum ligand, so that the exposure degree of the platinum center is remarkably reduced, interference of moisture and polar impurities in air is effectively inhibited, and the catalytic activity of the catalyst is improved. Therefore, the oxidation resistance and the storage stability of the catalyst are improved.
Owner:NANJING QINGQI NEW MATERIAL TECH CO LTD

High-heat-resistance polypropylene and preparation method thereof

The invention relates to high-heat-resistance polypropylene and a preparation method thereof, and belongs to the technical field of high polymer materials. The preparation method comprises the following steps: carrying out Michael addition reaction on 2-sulfydryl-1, 3-propylene glycol and vinyl dibutyl borate to prepare dihydric alcohol containing thioether and phosphate, and carrying out polymerization reaction on 1, 12-dodecanediol, boric acid ester dihydric alcohol and dimethyldichlorosilane to obtain the flame retardant. A polymer containing a borate group, a thioether group, organic silicon and a dodecane glycol ester group is prepared, the polymer is used as a heat-resistant toughening additive of polypropylene, the borate group and the organic silicon can improve the heat resistance and flame retardance of the polypropylene, and the thioether group and the dodecane glycol ester group can provide flexibility; therefore, the polypropylene is ensured to have good mechanical strength, heat resistance and flame retardance at the same time.
Owner:SUZHOU RUNJIA ENGINEER PLASTIC

Medical human body lubricant as well as preparation method and application thereof

PendingCN121102590ASurgeryCelluloseHuman body
The invention belongs to the technical field of medical or hygiene materials, and particularly relates to a medical human body lubricant and a preparation method and application thereof.The medical human body lubricant is prepared from, by mass, 1%-20% of glycerin, 1%-20% of propylene glycol, 0.1%-1% of hydroxyethyl cellulose, 0.05%-0.5% of carbomer, 0.05%-0.5% of sodium polyacrylate, 0.05%-0.5% of triethanolamine, 0.2%-1% of preservative and the balance purified water. The medical human body lubricant prepared by the invention has high moisture retention, is mild and non-irritant, and is suitable for people sensitive to skin.
Owner:HUNAN YUNTU BIOPHARMACEUTICAL CO LTD

Composition for enhancing Chinese chestnut fragrance of tea beverage as well as preparation method and application of composition

The invention discloses a composition for enhancing Chinese chestnut fragrance of a tea beverage as well as a preparation method and application of the composition, and belongs to the technical field of food additives. The composition is prepared from the following raw materials in parts by weight: 0.1 to 0.9 part of furanone, 0.01 to 0.2 part of linalool, 0.001 to 0.5 part of 2, 5-dimethylpyrazine, 0.02 to 0.1 part of geraniol, 0.03 to 0.05 part of beta-ionone and 0.01 to 0.25 part of geranyl acetone. According to the invention, through a unique ratio design, the scorched nut smell of pyrazine compounds, the rich caramel sweet taste of furanone, the stir-fried smoke and fire smell of 2-acetylthiazole and the freshness of geraniol and other terpene alcohols are ingeniously fused, and the complex level of Chinese chestnut fragrance is accurately reproduced. According to the present invention, the edible-grade propylene glycol is adopted as the solvent, such that the solubility, the dispersibility and the stability of the aroma composition in the tea beverage can be effectively improved, the persistence and the uniformity of the aroma release can be significantly improved, the shelf life of the tea beverage product can be easily prolonged, and the market competitiveness of the product can be enhanced.
Owner:SHANGHAI INST OF TECH

Combustion device and method for operating the same

ActiveCN116481025BCapillary burnersThermodynamicsFuel tank
A combustion device and a method for operating the same are disclosed. The combustion device uses at least 90 wt% of a propylene glycol-based liquid fuel and includes a first fuel tank, a second fuel tank, a pipe, and a driving unit. The first fuel tank is configured to contain the propylene glycol-based liquid fuel and is provided with a metal wick. A sensing unit is disposed in the first fuel tank and is configured to receive a start signal and to sense a liquid level of the propylene glycol-based liquid fuel in the first fuel tank, and to send a refueling signal. The second fuel tank is configured to contain the propylene glycol-based liquid fuel. The pipe is configured to communicate the first fuel tank and the second fuel tank. The driving unit is disposed on the pipe and is configured to receive the refueling signal, and to supplement the propylene glycol-based liquid fuel in the second fuel tank to the first fuel tank via the pipe, so as to achieve the effects of automatic refueling and cooling the wick.
Owner:DUTCH BUSINESS YOURAN INTELLECTUAL PROPERTY CO LTD

Super-branched high-performance environmentally friendly phthalate plasticizer, PVC product and preparation method and application thereof

The application discloses a kind of super branched chain high-performance environmentally friendly phthalate plasticizers, PVC product and its preparation method and application, belong to material technical field.The super branched chain high-performance environmentally friendly phthalate plasticizers are esterified and polycondensed by polybasic acid and mixed dihydric alcohol in the presence of catalyst, and are obtained by monohydric alcohol end-capping;Polybasic acid includes trimellitic anhydride, mixed dihydric alcohol includes at least two of methyl propylene glycol, neopentyl glycol, ethylene glycol and propylene glycol.The super branched chain high-performance environmentally friendly phthalate plasticizers are well compatible with PVC, good color, with good viscosity, density, acid value and other performance indicators, which is used in PVC product, can make PVC product not only has superior aging resistance and electrical insulation performance, but also has outstanding oil extraction resistance, migration resistance, volatile resistance and thermal stability performance.
Owner:GUANGDONG KEYUNCHENG NEW MATERIAL CO LTD

inkjet ink

To provide an inkjet ink that can be adjusted to an appropriate viscosity range and has excellent properties such as continuous and intermittent printing capabilities. [Solution] An inkjet ink is provided comprising a solvent containing a first solvent which is a glycol ether and a second solvent which is an alcohol having C1 to C3 carbon atoms, and a polyvinyl acetal resin, wherein the ratio of the second solvent to the total amount of the solvent is 5% by mass or more and 50% by mass or less. The first solvent may be propylene glycol monomethyl ether.
Owner:GENERAL CO LTD

Propylene glycol monosaturated fatty acid ester with pH buffering function and preparation method thereof

The invention discloses a preparation method of propylene glycol monosaturated fatty acid ester with a pH buffering function, which comprises the following steps: uniformly mixing liquid saturated fatty acid with propylene glycol, then adding a compound catalyst, reacting at 110-180 DEG C for 3-8 hours, and after the reaction reaches the end point, dehydrating to obtain the propylene glycol monosaturated fatty acid ester, the compound catalyst is a mixed aqueous solution of inorganic acid and hydroxide. According to the method, saturated fatty acid and propylene glycol are taken as main raw materials, a compound catalyst is added, and high-efficiency esterification synthesis is realized under certain reaction conditions. The prepared propylene glycol monosaturated fatty acid ester is good in color and luster, not only has good emulsifying performance, but also has an excellent pH buffering function, can maintain the stability of a system when an acid-base environment changes, and widens the application range of the propylene glycol monosaturated fatty acid ester in the fields of foods, cosmetics, medicines and the like. The method is simple in process, high in reaction efficiency, good in product chromaticity and environmentally friendly.
Owner:南京威尔药业科技有限公司

Minoxidil solution for androgen alopecia

The invention belongs to the technical field of pharmaceutical preparations, and discloses a minoxidil solution for androgenetic alopecia, which takes a deep eutectic solvent as a core solvent system and contains 1.0-5.0% of minoxidil (active ingredient), 0.1-1.0% of preservative, 0.05-1% of stabilizer, a proper amount of sodium hydroxide (the pH value is adjusted to 4-9) and purified water. According to the minoxidil solution, the solubility of minoxidil is greatly improved through the deep eutectic solvent, the solubility of minoxidil reaches 779.85 mg / ml and is 389.9 times that of water, the deep eutectic solvent is used in the minoxidil solution, ethanol is not contained, the dosage of propylene glycol is as low as 3%, ethanol and high-dosage propylene glycol (20%-50%) in a traditional commercially available formula are prevented from being used, irritation to scalp is reduced, and the minoxidil solution is suitable for scalp care. The minoxidil solution is stable in content after 6 months under the condition of 40 DEG C / 60% RH, the in-vitro transdermal performance of the minoxidil solution is superior to that of a commercially available reference preparation of an ethanol and propylene glycol solvent system, and the minoxidil solution also has the advantages of high stability, remarkable hair growth ability and the like.
Owner:HUBEI GUANGJI PHARM TECH CO LTD

Selective depolymerization method of polyester in polyester composite material

The invention relates to the technical field of polyester degradation, in particular to a selective depolymerization method of polyester in a polyester composite material. The selective depolymerization method comprises the following steps: carrying out a depolymerization reaction on a polyester composite material, a cosolvent, a depolymerization agent and a basic catalyst at normal pressure and a temperature not higher than 65 DEG C, the cosolvent is at least one of an ethylene glycol diether compound, a propylene glycol diether compound and an isobutyl ketone compound. According to the selective depolymerization method, an ethylene glycol diether compound, a propylene glycol diether compound and an isobutyl ketone compound are used as cosolvents, a depolymerization agent is used as a methylation reagent, and directional polyester depolymerization of a polyester composite material can be realized at normal pressure and the temperature not higher than 65 DEG C; when the polyester material is degraded, the non-polyester material is basically not degraded or depolymerized, and the selective depolymerization and separation of the polyester composite material such as a polyester blended fabric can be realized.
Owner:PUTIAN DAKAI NEW MATERIALS CO LTD

Method for detecting anions in phlegm-heat clearing injection

The invention discloses a method for detecting anions in a phlegm-heat-clearing injection, the detection method comprises the following steps: a test solution and a reference solution are taken for detection, the phlegm-heat-clearing injection is composed of scutellaria baicalensis, bear gall powder, cornu gorais, honeysuckle, fructus forsythiae and propylene glycol; chromatographic conditions of the detection are as follows: an anion exchange chromatographic column is adopted, an eluent is an acid aqueous solution, an alkali aqueous solution and / or a buffer salt aqueous solution, the flow velocity is 0.1-2.0 ml / min, the column temperature is 20-40 DEG C, a detector is an electrical conductivity detector, the detection mode is suppression electrical conductivity detection, and the sample size is 10-40 [mu] l; and obtaining the content information of the anions in the phlegm-heat clearing injection according to the detection result. The method disclosed by the invention is simple, convenient, efficient and rapid, and provides a theoretical basis for the quality control of the phlegm-heat clearing injection and the deep research of a pharmacodynamic material basis by detecting the content of the anions.
Owner:SHANGHAI KAIBAO PHARMACEUTICAL CO LTD

Pharmaceutical composition containing adapalene and benzoyl peroxide and preparation method thereof

PendingCN121818792AHydroxy compound active ingredientsAntisepticsContact dermatitisGlycerol
The invention relates to a pharmaceutical composition, which is prepared from adapalene, benzoyl peroxide, a traditional Chinese medicine extract, an acrylamide and acryloyl dimethyl sodium taurate copolymer, a mixture of isohexadecane and polysorbate 80, docusate sodium, EDTA (Ethylene Diamine Tetraacetic Acid) disodium, glycerol, poloxamer 124, propylene glycol and water, the traditional Chinese medicine extract comprises moutan bark, salvia miltiorrhiza, radix rehmanniae recen, radix sophorae flavescentis, coptis chinensis, rheum officinale, scutellaria baicalensis, menthol and borneol. According to the pharmaceutical composition disclosed by the invention, the synergistic antibacterial and anti-keratosis curative effects of adapalene and benzoyl peroxide can be maintained, and meanwhile, the occurrence rate of local skin dryness, erythema, desquamation, burning heat sensation and contact dermatitis can be remarkably reduced.
Owner:JIANGSU SEMPOLL PHARMA

A low pour point nonionic surfactant and a method for preparing the same

The application provides a low pour point nonionic surfactant and a preparation method thereof, which is composed of the following raw materials in parts by weight: C13 isomeric fatty alcohol polyoxyethylene ether 18-30 parts, reverse EO / PO block copolymer 10-20 parts, sodium diisooctyl sulfosuccinate 1-7 parts, sodium dodecyl sulfonate 1-5 parts, glyceryl laurate 1-5 parts, isopropyl alcohol 5-10 parts, and propylene glycol 1-5 parts; the formula is constructed based on a nonionic surfactant as a main body, ion surfactants and additives are introduced, and the system is optimized, so that a low pour point nonionic surfactant with excellent adsorption capacity and decontamination capacity is obtained.
Owner:HANGZHOU BAILANG AUXILIARY CO LTD