11results about How to "Simple treatment" patented technology

The present disclosure relates to an intestinal microorganism related to Huntington's disease and its application, wherein the application includes: the use of a product for detecting intestinal microorganisms in preparing a reagent or kit for assisting in diagnosing the occurrence of Huntington's disease in patients; the use of intestinal microorganisms in preparing a drug or kit for treating Huntington's disease; and the use of a product for detecting intestinal microorganisms in preparing a reagent or kit for evaluating the therapeutic effect of Huntington's disease. The present invention screens out intestinal microorganisms related to Huntington's disease, especially intestinal microorganisms related to the treatment of Huntington's disease, thereby opening up a new way to treat Huntington's disease.

Use of ritonavir in the manufacture of a medicament for the treatment of human cytomegalovirus infection. Ritonavir is used to inhibit replication of the HCMV immediate early phase. By targeting the HCMV immediate early protein 1, it is stifled at an early stage in the initiation of the HCMV viral gene expression program. This mechanism, which acts upstream in the viral life cycle, offers new possibilities for the treatment of HCMV infection.

The disclosure provides a new crystal form of ertapenem sodium and preparation method therefor. The new crystal form of ertapenem sodium has 27 principal characteristic peaks in an X-ray powder diffraction diagram. The crystal form of ertapenem sodium of the disclosure has a rod-like crystal habit, which has a large particle size, is not prone to aggregation and is easier to dry, and a product with high crystallinity and high purity may be obtained by simple drying treatment. Meanwhile, the crystal form of the disclosure has better stability, and the crystal form may remain unchanged to a maximum extent in subsequent washing and drying processes, thereby further improving the purity of the product.

The present invention discloses the use of DNA tetrahedron in preparing drugs for treating and preventing periodontitis, and belongs to the field of nucleic acid drugs. The present invention uses it to treat periodontitis, and its effect is excellent, and its efficacy is significantly better than that of antibiotics commonly used to treat periodontitis. The present invention provides a real therapeutic drug for clinical treatment of periodontitis, provides a new direction for the treatment of periodontitis, and has good application prospects.

A macrophage activator containing a Gc protein is provided by a simple process. The macrophage activator contains a Gc protein with no N-acetylgalactosamine attached thereto.

Provided are a recombinant human hyaluronidase formulation and an application thereof, the recombinant human hyaluronidase formulation comprising: recombinant human hyaluronidase, a buffer, a stabilizer, and a non-ionic surfactant, the stabilizer being selected from one or more of trehalose, sucrose, mannitol, sodium chloride, and methionine, and having the ability to maintain the stability of recombinant human hyaluronidase under 2-8 °C conditions; the hyaluronidase formulation can be applied in the preparation of a drug assisting subcutaneous infusion; same can enable a large volume infusion drug originally only able to be administered intravenously to be administered by means of subcutaneous infusion, and is more convenient, safe, and comfortable in clinical use.

The invention discloses a nano plasma photo-thermal treatment method and device capable of regulating and controlling a simulated drug. The method comprises the steps of microelectrode array device preparation, chronic arrhythmia model establishment and nano plasma photo-thermal treatment. A parameter-adjustable photo-thermal therapy system is established by combining a microelectrode array device, a gold nanorod, an electrophysiological recording instrument and a near-infrared laser, electrophysiological signals of myocardial cells are monitored synchronously, and the photo-thermal therapy effect is evaluated. The size and concentration of the gold nanorods and the intensity and duration of near-infrared laser irradiation are regulated and controlled, efficient and long-time chronic arrhythmia treatment is achieved, and an effective and simple method and system are provided for research of cardiovascular diseases.

This invention is a divisional application of application number 202010500967.1. The invention relates to a layered double hydroxide material system, its preparation method, and its application, specifically the application of LDH / EDTA layered double hydroxide materials in the preparation of antitumor drugs. The LDH / EDTA layered double hydroxide material is a zinc-aluminum layered double hydroxide loaded with ethylenediaminetetraacetic acid (EDTA); in the EDTA-loaded zinc-aluminum layered double hydroxide, EDTA is anion-exchange-intercalated into the interlayer space of the zinc-aluminum layered double hydroxide; the surface of the EDTA-loaded zinc-aluminum layered double hydroxide is positively charged.

The present application relates to the field of medical devices, and provides an ablation catheter and an ablation system comprising the same, the ablation catheter comprising a penetrating part, an ablation main body, a catheter main body and a control handle connected in sequence; the penetrating part comprises a screwing-in member capable of screwing into and being fixed to a target tissue under the action of an external force; the ablation main body comprises an ablation electrode, a connecting member and a temperature sensor; the catheter main body comprises a non-ablation electrode and a perfusion channel; the non-ablation electrode is arranged in a spaced manner with the ablation electrode, and the non-ablation electrode is not in contact with the target tissue during ablation. By using the ablation catheter and the ablation system, the thickened interventricular septum is screwed and ablated, the screwing speed is easier to control, the depth can be stopped or adjusted in time before penetrating the myocardial wall, myocardial perforation can be prevented, and the damage to the myocardial tissue is reduced through temperature detection and perfusion function.

The invention belongs to the technical field of medical and dental preparations, and provides siRNA of a targeted PITX2 gene and a medicine and application of the siRNA, the medicine is used for preventing and treating periodontitis and comprises the siRNA of the targeted PITX2 gene, and the siRNA is specifically combined with and targets mRNA of the PITX2 gene, so that expression of the PITX2 gene is blocked, and generation of inflammatory epithelial cells SAA1 + Epi in periodontal tissue is inhibited. According to the invention, the absorption degree of alveolar bone can be obviously reduced, and the progress process of periodontitis can be delayed.

The invention discloses a vaginal preparation which comprises an inert drug-loaded matrix, lactic acid and / or lactate, and a medical device or a bacteriostatic agent for treating and / or preventing female urogenital system diseases. In addition, the invention also discloses the preparation of the vaginal preparation, the use of the vaginal preparation for treating and preventing female urogenital system diseases, and the treatment method thereof.