1713 results about "Inhalation" patented technology

An electronic droplet delivery device having a mouthpiece of inhalation of droplets includes an aperture plate with a plurality of openings coupled to a piezoelectric actuator. A fluid reservoir supplies a solution with nicotine to the aperture plate for ejection out of the mouthpiece in a droplets stream.

Disclosed herein is a medical system (100, 400) comprising: a magnetic resonance imaging system (102) configured for providing a respiratory signal. The respiratory signal is descriptive of a respiratory position as well as of inhalation and exhalation of the subject. The execution of machine executable instructions (140) causes the computational system to repeatedly: perform (200) the individual acquisition of k-space data using the magnetic resonance imaging system; receive (202) the respiratory signal; bin (204) the individually acquired k-space data into one of a predetermined number of k-space bins (148) using the respiratory signal and perform outlier rejection. Execution of the machine executable instructions further causes the computational system to reconstruct (208) a magnetic resonance image for each of the predetermined number of k-space bins to provide a respiratory-state resolved magnetic resonance image (150).

The invention relates to the field of anesthetic concentration regulation and control, in particular to a method for analyzing and evaluating the administration concentration of an inhalation type anesthetic. The method comprises the following steps: firstly, according to characteristic data such as basic physiological data, previous anesthesia sensitivity and operation information of a patient, applying a fuzzy matching algorithm to obtain an initial administration concentration; physiological sign data such as blood pressure, heart rate, pulse oxyhemoglobin saturation and end-expiratory carbon dioxide partial pressure of the patient are monitored in real time in the anesthesia process and compared with a normal range, whether the physiological sign data are abnormal or not is judged, and an adjustment scheme of the administration concentration is determined according to the administration concentration-physiological sign correlation model; after the administration concentration is adjusted, the electroencephalogram double-frequency index is monitored to evaluate the anesthesia depth, the anesthesia depth matching degree is analyzed to judge the adjustment effect, and therefore closed-loop control over the anesthetic administration concentration is achieved. According to the method, the administration concentration can be accurately regulated and controlled, the concentration regulation mechanism is optimized, the safety and effectiveness of the anesthesia process are effectively improved, and a reliable guarantee is provided for clinical anesthesia.

The invention relates to the technical field of emotional robots, and discloses an embracing emotional robot which comprises an inner shell, low-cost and high-simulation breathing simulation is achieved through cooperative control of an air pump and an air valve, and the embracing emotional robot is designed by combining simulation body temperature brought by a heating piece and synchronous action of a rotatable arm. The emotion robot can naturally rotate forwards when being embraced and is matched with simulated respiration and simulated body temperature, so that the immersion and emotion interaction experience of a user are remarkably improved; the operation cycle of the air pump strictly follows biological breathing characteristics, the inspiration stage accounts for 2 / 3 of the breathing cycle, the speed of the inspiration stage changes fast and slow, the expiration stage accounts for 1 / 3 of the expiration stage, smooth pressure relief is achieved through the air valve, and the highly-simulated breathing mode can effectively guide a user to breathe synchronously, so that parasympathetic nerves are activated, the anxiety level and heart rate fluctuation are reduced, and the user experience is improved. And the whole structure adopts a modular design, complex functions such as breathing simulation, embracing and body temperature simulation can be realized, the maintenance is convenient, and the device is particularly suitable for long-term accompanying scenes.

The invention belongs to the technical field of bionic nano-drugs, and particularly relates to a bionic vesicle preparation as well as a preparation method and application thereof. The bionic vesicle preparation disclosed by the invention is prepared from the following raw materials: mesenchymal stem cell outer vesicles, nintedanib and DSPE-PEG-HA (hyaluronic acid modified pegylated phospholipid); the nintedanib is loaded in the mesenchymal stem cell outer vesicle, and the DSPE-PEG-HA is coupled to the surface of the mesenchymal stem cell outer vesicle. The bionic vesicle preparation disclosed by the invention can be used for directly delivering a drug to a pulmonary fibrosis injury part through inhalation type drug delivery, and acting on a focus part at a higher local concentration, meanwhile, the exposure of the drug in whole-body circulation is remarkably reduced, the occurrence of side effects is reduced, and the specific targeting intervention and regulation on fibroblasts are realized.

The invention provides an inhalable tanshinone IIA lipid nanocrystal as well as a preparation method and application thereof, and the inhalable tanshinone IIA lipid nanocrystal is mainly formed by entrapping tanshinone IIA by using dipalmitoyl phosphatidylcholine DPPC and dipalmitoyl phosphatidyl ethanolamine DPPE as mixed phospholipids in the presence of a stabilizer. Compared with the prior art, the inhalable tanshinone IIA lipid nanocrystal disclosed by the invention has the advantages that by improving the physicochemical property and drug release behavior of TA, the lung retention volume of TA after aerosol inhalation is obviously increased, the retention time of TA in the lung is prolonged, and the risk of toxic and side effects caused by whole-body escape of drugs is reduced; the treatment effect on idiopathic pulmonary fibrosis is improved, and the compliance of a patient is improved.

The invention discloses an intelligent atomization control method and system for respiratory tract treatment and a storage medium, and relates to the technical field of atomization control. During operation of the system, a multi-mode patient respiratory behavior monitoring module is used for capturing real-time respiratory frequency, depth, rhythm, cough characteristics and atomization efficacy based on a non-contact sonic sensor and lung sound analysis; the method comprises the following steps: monitoring environment humidity, temperature and aerosol diffusion rate in real time, analyzing the influence of the environment humidity, temperature and aerosol diffusion rate on drug mist particle size and sedimentation behavior, controlling atomization particle size through a variable-frequency ultrasonic exciter, calculating to obtain an intelligent atomization curative effect adaptation index AEAI, dynamically adjusting particle size distribution according to the real-time inhalation demand of a patient and environment parameters, and combining with respiration monitoring data to obtain the intelligent atomization curative effect adaptation index AEAI. According to the method, the medicine mist release opportunity is adjusted in real time, threshold value comparison is carried out by monitoring respiratory resistance changes and real-time feedback of lung sound characteristic improvement degree, a medicine release strategy is obtained, and remote doctor viewing and parameter adjusting functions are provided.

The invention relates to the technical field of atomization rate control, in particular to an intelligent atomization compliance monitoring method and system for children. The method comprises the following steps: firstly, acquiring expiration flow velocity, inspiration flow velocity and multi-direction motion acceleration time sequence data of a child in a historical monitoring period, and reflecting breathing and behavior action conditions; dynamically analyzing the numerical characteristics of the expiration flow velocity and the inspiration flow velocity to divide a respiratory cycle, and analyzing the cycle length, the inspiration flow velocity cumulant and the like to construct a respiratory characteristic vector; screening a target monitoring period based on the breathing feature vector and the period number similarity; further analyzing the motion acceleration change and accumulation characteristics in the target monitoring period, and quantifying the behavior compliance expression degree; the behavior compliance expression degree and the breathing feature vector are deeply fused, a'breathing state-behavior cooperation 'joint evaluation model is established, the breathing and behavior states of children are dynamically recognized, the medicine atomization rate is accurately adjusted, and effective deposition of lung medicine is improved.

The utility model relates to the technical field of equipment testing, in particular to a passive following type respirator testing device and system.The device comprises a respiration simulation assembly provided with a passive following type respirator; the muscle simulation assembly is connected with the respiration simulation assembly and used for driving the respiration simulation assembly to move and simulating the expiration and inspiration exchange process of the human body based on the movement of the respiration simulation assembly; and the upper computer is communicated with the muscle simulation assembly and is used for inputting a test instruction to enable the muscle simulation assembly to move and outputting a test result of the passive following type respirator according to the test data of the passive following type respirator. Therefore, the problem that the test accuracy is low due to the fact that the simulated lung lacks a power source and the spontaneous respiration state of human muscles cannot be simulated in the prior art is solved.

The invention relates to a breathing pipeline adapter capable of adjusting the air displacement and a breathing nasal mask.The breathing pipeline adapter comprises a tubular body, a through airflow channel is formed in the tubular body, the tubular body is provided with a first end and a second end, the first end is used for being connected with nasal masks of different models, and the second end is used for being connected with an external breathing pipeline; the exhalation hole group comprises a plurality of exhalation holes, and the multiple exhalation holes are uniformly formed in the circumferential outer wall of the tubular body in an annular array mode and directly communicate with the airflow channel; the adjusting knob is coaxially arranged on the outer side of the tubular body in a sleeving mode, and a through hole is formed in the adjusting knob; the through holes can be aligned with or staggered with different numbers of exhalation holes, and the air displacement of the airflow channel is adjusted. According to the breathing nasal mask, the exhaust area can be adjusted, exhaled air can be exhausted out of the nasal mask more effectively, for a patient with a large amount of exhaled air, the effective exhaust area can be increased, the exhaled air can be exhausted in time, accumulation of the exhaled air in the nasal mask is avoided, and therefore the relapse phenomenon is reduced.

The invention discloses an atmospheric environment exercise health monitoring method and system, and the method comprises the steps: S1, generating a pollution level distribution diagram based on air quality index data collected in real time, S2, determining an air quality risk value of a current region according to the pollution level distribution diagram, and S3, determining the air quality risk value of the current region according to the air quality risk value. S3, based on the air quality risk value, calculating a dynamic movement duration threshold value adaptive to human health; S4, regulating and controlling the actual movement duration of the user according to the dynamic movement duration threshold value so as to prevent pollutant inhalation from exceeding the standard; according to the atmospheric environment movement health monitoring method and monitoring system, the movement duration is regulated and controlled according to the real-time fluctuation of the air quality index, so that the problem that pollutants inhaled by the human body exceed the standard is solved.

The invention discloses a contrast agent injection regulation and control device, and relates to the technical field of contrast agent injection.The contrast agent injection regulation and control device comprises an injection pipe, one end of the injection pipe is fixedly connected with a limiting plate, a piston is slidably installed in the injection pipe, a drawing rod is installed on one side of the piston, and one end of the drawing rod is fixedly connected with a pushing piece; a limiting ring is fixedly connected to the outer portion of the drawing rod, first limiting grooves are symmetrically formed in the outer portion of the injection pipe, and an adjusting mechanism is arranged on the outer portion of the injection pipe. The position of the positioning mechanism can be changed by moving the adjusting mechanism, the scale strip is arranged outside the injection tube, the adjusting mechanism can be conveniently moved to a proper position, and when a contrast agent is sucked, due to the cooperation of the positioning mechanism and the limiting ring, the drawing rod can only move to a designated position, so that the amount of the sucked contrast agent is guaranteed, and the contrast agent suction efficiency is improved. The situation that the subsequent radiography effect is affected after too much or too little inhalation is injected into the body of a patient is avoided, and adjustment can be conveniently conducted according to the condition of the patient.

The invention relates to the field of intelligent medical treatment, in particular to a radioactive monodisperse particle preparation, aerosol generation and animal inhalation deposition in-situ quantification method. Comprising the following steps: acquiring aerosol generation standard particles and radioisotopes; adding the standard particles and radioactive isotopes into a PBS solution, and carrying out an oxidation-reduction reaction to obtain a reaction solution; the reaction solution is washed and filtered through deionized water until no separable gamma activity exists, and the radioactive standard particles used for aerosol generation are obtained.The radioactive aerosol generation particles with the single particle size can be obtained and have good clinical value.

The present disclosure provides embodiments of a personal protective device which include one or more sensors. The personal protective device is in the form factor of a filtered mask to cover the nose and the mouth of the subject when in use. One or more sensor modules are connected to the mask for detecting one or more parameters related to an inhalation and or exhalation of the subject. The mask is held onto the face of the subject by one or more support members.

The invention provides a heating and humidifying high-flow oxygen uptake bottle which comprises a humidifying oxygen uptake bottle, and an in-bottle oxygen outlet pipe and a gas passage partition plate are sequentially arranged in a humidifying cavity of the humidifying oxygen uptake bottle from top to bottom. A proper amount of humidifying liquid is arranged in a humidifying bottle cavity, and a closed oxygen humidifying channel is formed between the gas passage partition plate and the liquid level of the humidifying liquid to humidify oxygen flow. A heating structure is arranged at the bottom of the bottle to heat, humidify or heat and disinfect oxygen flow, water and electricity are separated, and comfort and safety of oxygen inhalation are guaranteed; oxygen flow is humidified and heated on the surface of humidifying liquid, the water adding amount is large, the humidifying and heating effects are stable, and safety and reliability are achieved; the oxygen uptake bottle can be disinfected at any time according to needs, and cross infection is avoided.

The invention relates to the technical field of oxygen inhalation and humidification, and discloses a medical oxygen inhalation and humidification device which comprises a first box body, the top of the first box body is fixedly connected with a shell, the top end of the shell is fixedly connected with a second box body, the second box body is fixedly connected with an air outlet pipe, and the top of the first box body is fixedly connected with an air inlet pipe. The air inlet pipe is sequentially communicated with the first box body, the shell, the second box body and the air outlet pipe. According to the medical oxygen inhalation and humidification device, when oxygen inhalation operation is carried out, oxygen makes contact with distilled water in the first box body, humidification of the oxygen is achieved, and therefore follow-up humidification and oxygen inhalation operation can be conveniently carried out; according to the medical oxygen inhalation and humidification device, oxygen can make contact with distilled water by changing the valve on the air inlet pipe, humidification and oxygen inhalation are achieved, oxygen can be directly discharged, and normal oxygen inhalation operation is achieved; according to the medical oxygen inhalation humidification device, during humidification operation, the atomization piece is opened, atomized distilled water and oxygen are mixed and then inhaled by a patient, and the humidification effect is improved.

The present disclosure relates to an inhaler component for producing a steam / air mixture or / and condensation aerosol in an intermittent and inhalation- or pull-synchronous manner, the inhaler component including: a housing; a chamber arranged in the housing; an air inlet opening for the supply of air from the surroundings to the chamber; an electrical heating element for evaporating a portion of a liquid material; and a wick having a capillary structure, which wick forms a composite structure with the heating element and automatically supplies the heating element with fresh liquid material after evaporation.

The present invention discloses an adjustable resistance breathing trainer, comprising a housing, the top of which is provided with a first air inlet and outlet; a resistance movable upper cover, which is provided at the upper inner portion of the housing and can be raised and lowered along the housing; an exhaust port is provided on the side wall of the housing at a position corresponding to the exhaust chamber; a top seal is movably provided on the top of the resistance movable upper cover; a resistance movable lower cover is movably provided on the lower side of the resistance movable upper cover; an elastic member is provided between the resistance movable upper cover and the resistance movable lower cover; an inhalation resistance adjusting member is connected to the resistance movable lower cover via an external thread; the upper end of the resistance connecting member is connected to the top seal, and the lower end extends into the inhalation resistance adjusting member; an adjustable bottom cover is provided at the lower end of the housing; and an exhalation resistance adjusting member, the outer side of which is provided with an external thread and is engaged with the outer shell thread via the external thread. The present invention has a wide range of resistance coefficient adjustment levels and a controllable tolerance range, and is suitable for all training needs of different groups of people.

Methods, apparatuses, and systems for mechanically releasing a predetermined amount of supplemental oxygen to a user via a mechanical initiator are disclosed with the release of the amount of supplemental oxygen based on and in response to the combined factors of a user's determined oxygen consumption based on sensing a user's inhalation combined with determining the ambient pressure in the area of the user.

The present invention relates to a pharmaceutical composition in inhalable pre-metered dry powder form that comprises at least one excipient (for example carrier) and at least one active substance used against viral diseases to locally administer it to the lungs for use in the treatment of symptoms of viral lung diseases including COVID-19 caused by Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-COV-2) by means of dry powder inhaler through inhalation. The present invention also relates to methods for preparation of said pharmaceutical composition and the use of these active substances in symptoms caused by COVID-19. similar viral lung diseases, influenza.

The invention belongs to the technical field of biological medicine, and particularly relates to application of corynebacterium casei in preparation of medicine for preventing and treating lung injury. By constructing a radon inhalation-induced lung injury mouse model, after exposure at different radon levels, the weight of a mouse is reduced, the lung coefficient is increased, the tidal volume of the lung, the ventilation volume per minute and the maximum inspiration flow are reduced, the respiratory function is inhibited, the alveolar cavity of the mouse is abnormally expanded, the pulmonary septum is thickened and fractured, and more fibrin exudation is accompanied; the traditional Chinese medicine composition can be used for effectively inhibiting pulmonary fibrosis and lung injury due to obvious inflammatory infiltration beside bronchial tubes, extravasated blood in small blood vessels and lung tissue collagen deposition, and can be used for gavage of corynebacterium casei to effectively inhibit the above phenomena. Therefore, the corynebacterium casei can be used for preventing and treating lung injury, especially lung injury caused by radon exposure.

The present disclosure relates to an inhaler component for producing a steam / air mixture or / and condensation aerosol in an intermittent and inhalation- or pull-synchronous manner, the inhaler component including: a housing; a chamber arranged in the housing; an air inlet opening for the supply of air from the surroundings to the chamber; an electrical heating element for evaporating a portion of a liquid material; and a wick having a capillary structure, which wick forms a composite structure with the heating element and automatically supplies the heating element with fresh liquid material after evaporation.

The invention includes dry powder nintedanib formulation for dispersion and inhalation administration including salts thereof, indolinone derivative or salts thereof and in fixed dose combinations with carrier agents and other active ingredients. The aerosol delivery combination formulation may be administered as an inhaled aerosol over a few actuations or by two or more actuations. Each dose may be administered one or more times daily on a regular or interval daily dosing regimen. The special formulation parameters of the invention include the selection of the salt for complexation with the form of nintedanib used for an isolated dry powder along with particle size distributions and combination with a force control agent for improved aerosol delivery. Methods of the invention include therapeutically effective doses of the described invention used to treat interstitial lung disease.

The invention provides an inhalation medication auxiliary device, relates to the technical field of medical instruments, and solves the technical problem that a large force is needed when a puncture part of an inhaler is pressed to puncture a capsule. The inhalation medication auxiliary device comprises a shell and an automatic puncturing module, and the shell covers an inhaler and is used for fixing the inhaler; the automatic puncturing module is arranged on the shell and used for automatically puncturing the capsule placed in the inhaler. According to the embodiment of the invention, the automatic puncturing of the capsule in the inhaler is realized through the automatic puncturing module arranged on the shell, so that the technical problems that large force is needed when the puncturing part of the inhaler is pressed to puncture the capsule, a user with weak force is difficult to press, and the inhaler is not friendly to old and young users are solved.

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a beclomethasone propionate suspension for inhalation and a preparation method of the beclomethasone propionate suspension. The preparation method of the beclomethasone propionate suspension for inhalation mainly comprises the following steps: S1, preparing sterile beclomethasone propionate particles by using a supercritical fluid rapid expansion method, and collecting the sterile beclomethasone propionate particles into a sterile glass beaker; s2, adding sterile water in which a surfactant is dissolved, and dispersing by ultrasonic dispersion equipment; s3, preparing an auxiliary material solution of beclomethasone propionate, and filtering by using a sterile filter membrane; s4, mixing the solution in the step S2 and the solution in the step S3, and dispersing by using ultrasonic dispersion equipment; and step S5, filling and sealing into an ampoule bottle to prepare the beclomethasone propionate suspension for inhalation. The beclomethasone propionate suspension for inhalation is more uniform in particle size distribution and good in stability, the preparation process is carried out under relatively mild conditions, and the technological operation is simple and convenient.

The invention discloses an atomization machine for adjuvant therapy of children cough, and relates to the technical field of atomization therapy, the atomization machine comprises a main machine, an atomization cup, a respiration adjusting assembly and a respiration piece, the atomization cup is provided with a mist outlet pipe, the respiration piece is installed at the tail end of the mist outlet pipe, and the respiration adjusting assembly is installed between the respiration piece and the mist outlet pipe; the breathing adjusting assembly comprises an adjusting and controlling part and a flow guiding part, an airflow sensor used for monitoring the breathing direction and the airflow quantity and a flow guiding blade used for guiding the airflow direction are arranged in the flow guiding part, adjusting and controlling blades used for adjusting and controlling the inspiration resistance are arranged in the adjusting and controlling part, and the adjusting and controlling blades can adjust the shape according to signals fed back by the airflow sensor. Therefore, the breathing resistance is increased or reduced. The breathing state is monitored through the air flow sensor, the resistance is dynamically adjusted through the breathing adjusting assembly, a child is guided to form a slow and deep standard atomization breathing rhythm in cooperation with seeing and hearing of the display screen, turbulent flow is avoided through the flow guide blades, fog particles are pushed to directly reach the lung, and meanwhile expired air is prevented from polluting medicine liquid.

A single dose disposable powder aerosol device belongs to the field of medical devices. It is composed of a bottom cover, a suction nozzle and a sliding cover. The suction nozzle and the sliding cover are assembled on one side of the bottom cover. The suction nozzle is assembled on the front half of the bottom cover, and the sliding cover is assembled on the rear half of the bottom cover. An air inlet, a medicine pit, a medicine inlet channel and a vortex cavity are sequentially arranged on the bottom cover. At least one side air inlet is arranged on the side of the vortex cavity. An ascending air duct and a medicine outlet are sequentially arranged in the suction nozzle body. After the bottom cover, the suction nozzle and the sliding cover are assembled into one, the air inlet, the medicine pit, the medicine inlet channel, the vortex cavity, the ascending air duct and the medicine outlet form a complete flow channel cavity. The filling operation of the medicine powder in the medicine pit is realized through three steps of sliding the sliding cover, loading the medicine powder and closing the sliding cover. The sliding cover structure is adopted, which is convenient for the filling operation or supplement of the built-in medicine powder, and can be switched between disposable and reusable types. It can be widely used in the design and manufacture field of inhalation type drug delivery devices.

The utility model discloses a pump head damping structure which comprises a shell, a suction cavity, a compression cavity, a discharge cavity and an energy storage cavity are formed in the shell, the suction cavity is sequentially communicated with the energy storage cavity through the compression cavity and the discharge cavity, a water inlet pipe opening and a water outlet pipe opening are formed in the shell, and a water outlet pipe opening is formed in the shell. A water inlet pipe opening is formed in the shell, a water outlet pipe opening is formed in the shell, the water inlet pipe opening is communicated with the suction cavity, the water outlet pipe opening is communicated with the energy storage cavity, a vibration reduction cavity is further formed in the shell, an elastic vibration damping piece is arranged between the vibration reduction cavity and the energy storage cavity, the elastic vibration damping piece is connected with the vibration reduction cavity in a sealed mode, and the elastic vibration damping piece is connected with the energy storage cavity in a sealed mode. The damping structure can solve the problem that the damping effect is reduced after the damping structure works for a long time.

A combined system of a concealed closed tracheoscope and an artificial airway breathing circuit includes an artificial airway breathing tubing and a tracheoscope. The artificial airway breathing tubing includes an inhalation circuit and an exhalation circuit that are connected through a connecting tube. The tracheoscope includes a handle portion and an insertion portion connected to the handle portion. The tracheoscope handle portion wraps around a section of the exhalation circuit. The tracheoscope insertion portion is hidden in the extendable breathing circuit, which extends and retracts to make the tracheoscope insertion portion advance or retreat in a closed condition. The tracheoscope handle function assembly cleverly wraps around the surface of the breathing circuit tubing, organically combining the functions of the tracheoscope handle and the breathing circuit. Meanwhile, the tube interface can be cleaned to keep the tracheoscope clean and unobstructed, such that the service life of the tracheoscope can be extended.

The invention belongs to the technical field of medical equipment, and particularly relates to a portable tuberculosis drug aerosol inhalation device. The device comprises a medicine storage chamber, an outflow channel and a controller, the top of the medicine storage chamber is provided with a medicine tank groove with a conical pricking pipe, and one-step medicine filling through placing and pressing can be achieved; the respiratory rhythm of a user is identified through lip contact and a respiratory airflow sensor, and the atomizer is synchronously controlled to start and stop; the system has the functions of liquid medicine identity recognition, heating temperature control and self-adaptive power adjustment based on liquid medicine storage, efficient, safe and comfortable tuberculosis medicine inhalation treatment is achieved, and the medication compliance and the treatment effect are remarkably improved.