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7218 results about "Diabetes mellitus" patented technology

A metabolic disorder in which the body has high sugar levels for prolonged periods of time.

Pyrazole compounds useful as protein kinase inhibitors

This invention describes novel pyrazole compounds of formula IIIa: wherein R1 is T-Ring D, wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; Rx, Ry, R2; and R2′ are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of Aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.
Owner:VERTEX PHARMA INC
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