The invention provides
glabridin nano-vesicles based on glycyrrhizic acid wrapping, a preparation method of the
glabridin nano-vesicles and application of the
glabridin nano-vesicles in preparation of whitening and
skin care
cosmetics, and relates to the technical field of
cosmetics. According to the glabridin nano-
vesicle based on glycyrrhizic acid wrapping, glabridin is carried by glycyrrhizic acid, glycyrrhizic acid serves as a carrier, the
solubility of glabridin can be improved, the
skin transmittance of glabridin can be increased, the anti-inflammatory effect of glabridin can be achieved, then the effect of one stone for three birds is achieved, the characteristic and
advantage of integration of
medicine and auxiliary materials are achieved, and the glabridin nano-
vesicle based on glycyrrhizic acid wrapping has good application prospects. The
tyrosinase inhibition activity of the glabridin is greatly improved. Meanwhile, the glabridin nano-vesicles wrapped based on glycyrrhizic acid have the advantages of high encapsulation efficiency, large
drug loading capacity, good stability and high safety, can effectively promote the whitening factor glabridin to penetrate through the
skin cuticle to enter the skin
deep tissue, can stay in the skin at a
high concentration for a long time, and can continuously play a whitening role.