The invention belongs to the technical field of information, and provides an information interaction system for industrial interconnection. The system utilizes a message queue, a message flow engine, an information management shell, a protocol wrapper and a service-oriented architecture technology to design an integration interconnection engine; the integration interconnection engine enables various IT systems such as an SRM (a supplier relation management system), a CRM (a customer relation management system), an MES (a manufacturing execution system), a PLM (a product life cycle management system) and an ERP (an enterprise resource planning system) in the management field to be mutually connected through an enterprise internal network, and enables various OT systems and physical devices such as an SCADA (a data acquisition and monitoring control system), a DCS (a distributed control system), an MOM (a manufacturing operation management system), a sensor, a robot and the like in the operation execution field to be mutually connected through the industrial Internet of Things, therefore, a huge bottleneck that data are difficult to integrate when an enterprise realizes interconnection, intercommunication and interoperation of industrial total elements, a total value chain and a total industry chain is overcome.