394results about How to "Good water solubility" patented technology

The present invention relates to butylbenzene phthalein cyclodextrin or cyclodextrin derivative clathrate, its preparation method and application. The described butylbenzene phthalein is mixed-rotatory butylbenzene phthalein and levo-butylbenzene phthalein. In order to raise water solubility of butylbenzene phthalein and develop solid dosage form and liquid dosage form required for clinical application said invention adopts cyclodextrin or cyclodextrin derivative to include the butylbenzene phthalein. Said clatherate contains butylbenzene phthalein and cyclodextrin or cyclodextrin derivative, the mole ratio of both them is 1:1-10. The cyclodextrin or cyclodextrin derivative optimally selects hydroxypropyl-beta-cyclodextrin. Said clathrate can be used for preparing various dosage forms of injection, oral preparation, tablet, capsule and others.

The invention relates to a water-soluble fracturing-acidifying temporary-stopping agent, used in temporary- stopping bed of oil water well in the course of selecting fracturing and multi-crack fracturing. It is comprised of bone glue, sulfonated pitch and guargum in the weight ratio of 5.5-6.5 to 1.5-3.5 to 1-2. Its preparing method is taking a certain amount of water to heat and keep the temperature at 70-80 deg.C, adding in bone glue and stirring, dissolving; when the temperature is lowered to 40-50 deg.C, adding in sulfonated pitch and stirring uniformly; adding in guargum and strongly stirring uniformly; pouring into a special container, spreading out into an about 3mm-thick cake in shape, and naturally drying; crushing and then screening, and selecting the particles with 3-6 mm diameter as the finished product. It is fast to dissolve, low-cost and strongly-stopping.

The invention discloses an illegal cooking oil lubricant and a preparation method thereof. The illegal cooking oil lubricant comprises the following components in percentage by weight: 40%-60% of illegal cooking oil, 0.5%-1.5% of sodium sulfite, 1%-3% of sorbide oleate, 0.02%-0.04% of antioxidants, 0.2%-0.3% of extreme-pressure antiwear agents, 0.05%-0.1% of formaldehyde, 1.0%-1.2% of sodium hydroxide and the balance of water. Through the illegal cooking oil lubricant disclosed by the invention, the problem that torque and friction resistance are reduced through lubrication in the drilling process of a horizontal well is effectively solved, moreover, a new way is provided for the recycling of the illegal cooking oil, and the preparation cost of the lubricant can be reduced.

The present invention provides a WTR medium voltage insulating cable material and a cable made of the material, and pertains to cable domain. A medium voltage WTR irradiated polyethylene insulating material is produced by adding a compound WTR growth promoting agent; the compound WTR growth promoting agent comprises hydrogenated polysaccaride, organized montmorillonite, maleic anhydride grafts, and silicone polymer between molecular weight 1000-5000; the parts by weight of the ingredients of the WTR medium voltage insulating cable material are: low density polyethylene: 100, maleic anhydride grafts: 2-10, hydrogenated polysaccaride: 0.2-1, organized montmorillonite: 0.01-1.5, silicone polymer: 0.01-1.5, cross-linking agent: 2-3, and antioxidant: 0.3-0.5. The insulating material in the present invention has WTR growth function, break through the bottle neck of WT growth of the cable insulation itself, and can prolong the service life of the cables. With the WTR medium voltage insulating cable material, environment protective halogen-free flame retardant medium voltage WTR irradiated polyethylene insulated power cables or PVC medium voltage WTR irradiated polyethylene insulated power cables can be manufactured.

A water-soluble zwitterionic copolymer contains two structure units: 2-methyl-2- acrylamido propanesulfonic acid and methyl acrylyloxyethyl trimethyl ammonium chloride. Its preparing process includes such steps as proportionally adding the anhydrate sorbitol monooleate and the anhydrated sorbitol monostearate to kerosene, proportionally dissolving two monomers in water and regulating its pH=7, proportionally mixing oil phase with water phase, filling N2, adding redox trigger, and redox reaction in constant-temp water bath.

The present disclosure provides methods and compositions for increasing production in animals by feeding the animals a composition which includes a soluble dextrin product. The composition may be fed to the animal in the form of a complete feed, a concentrate, a pre-mix, and a top-dress and may be in either a liquid or solid formulation.

The present invention relates to hemostatic materials made of water-soluble cellulose ether derivatives, such as methylcellulose, ethylcellulose, hydroxyethylcellulose, and pharmaceutically acceptable salts of carboxymethylcellulose, especially to hemostatic materials made of water-soluble cellulose ether derivatives capable of being absorbed in live body. The present invention also relates to the use of water-soluble cellulose hemostatic materials for the preparation of internal and external hemostatic articles and pharmaceutical compositions, and hemostatic articles and pharmaceutical compositions thereof.

The invention belongs to the field of biological engineering and relates to chitosan modification. The chitosan modification comprises the following steps of: adding protein or polypeptide; adding transglutaminase; adjusting the pH value; removing precipitates after full reaction; and desalting and drying for modification. The modified chitosan produced by the technical scheme disclosed by the invention is good in water solubility, does not generate precipitate at the pH value of 3-10, and is small in viscosity. Moreover, the functions including strong adsorption, antibacterial property and the like of the chitosan are kept, and the application prospect is extensive.

The invention discloses water-soluble copolyester and a preparation method thereof. Caprolactone, dicarboxylic acid or ester thereof, m-benzene sulfonate and dihydric alcohol are adopted as raw materials, and the method comprises the following steps of: raising the temperature to catalyze quick ring opening; and raising the temperature for esterification and polycondensation. The polyester resin has good water solubility and better adhesion; and when used for textile sizing, the polyester resin can well adhere to hairs to greatly reduce the end breakage of warp yarns in the weaving process; therefore, the production efficiency and the quality of textiles are improved.

The invention discloses a preparation method of submicron CuS (copper sulphide) classification balls. The method comprises the following steps: adding polymer into a good solvent to dissolve and remove big gel particles; adding copper source solution to the good solvent and stirring; adding sulfur source solution and then stirring; reacting the reaction liquid under 100-1,000 KPa at 100-200 DEG C; naturally cooling to the room temperature to obtain black precipitate; and washing and drying the precipitate to obtain the classification balls. The classification balls has the advantages of cheap and readily available templates, environmental friendliness, safety without toxicity, renewability and high water solubility, the contents of raw materials are abundant in nature and the operation of the reaction system is simple; the size and structure of the prepared classification ball are adjustable: the diameter can be controlled by adjusting the molar weight of the added precursor, the template concentration, the reaction temperature and time and the like; the operation is simple; and the prepared classification balls have wide application value in the fields of catalyst, catalyst carrier, optical equipment, sensor, lithium-ion rechargeable battery cathode material, superconductor and the like.

The invention provides a method for preparing micron spherical silver powder. The method comprises the following steps of: preparing silver nitrate and ascorbic acid solution at certain concentration; mixing polyethylene glycol serving as a dispersant and the ascorbic acid solution; adding ethanol serving as a defoamer into the mixed liquor under stirring, and adjusting the pH value of the solution; and adding silver nitrate solution for reaction, standing, separating liquid from solid, and washing and drying the solid to obtain the micron spherical silver powder to ensure that the silver powder has a smooth surface, less agglomeration, high dispersibility, the impurity content of less than 5*10<-4>, the specific surface area of between 1.2 and 1.5 m<2>/g, the tap density of about 1.4 g/ml, the loose density of about 1.1 g/ml and the particle size distribution of between 0.5 and 1.13 mu m. Conductive silver paste can be prepared by grading the micron spherical silver powder and flake silver powder, and the micron spherical silver powder can be used for producing solar cell components, electronic components such as flake or circular ceramic capacitors and the like, automobile glass heating wires and the like.

The invention discloses water-soluble up-conversion nanoparticles and a preparation method thereof. The preparation method includes steps of firstly adopting the high-temperature thermal decomposition method to synthesize up-conversion luminescent nanoparticles (UCNPs), adopting NOBF4 to treat the UCNPs for replacing oleic acid molecules on the surface of the UCNPs, finally subjecting the UCNPs to reaction with hydrophilic hyperbranched polymers to obtain the water-soluble up-conversion nanoparticles. The water-soluble up-conversion nanoparticles are good in water solubility and high in light intensity and provided with active groups such as amino, carboxyl and hydroxyl available for coupling biomacromolecules and have promising application prospect in bioimaging, fluorescent labelling, drug carriers and the like.

The invention discloses a denitration catalyst regeneration solution and a preparation method thereof as well as a catalyst regeneration method. The denitration catalyst regeneration solution comprises the following raw material ingredients in parts by weight: 4-6 parts of vanadyl oxalate, 0.08-0.10 part of cerium nitrate, 0.11-0.13 part of lanthanum nitrate, 0.05-0.07 part of copper nitrate, 0.4-0.6 part of silica sol ST-O and 95 parts of deionized water. The catalyst regeneration method comprises the following steps of firstly, evenly mixing vanadyl oxalate and the deionized water; then, feeding cerium nitrate, lanthanum nitrate and copper nitrate into mixed solution, and fully stirring until the mixture is completely dissolved; finally, feeding silica sol ST-O, and continuing to stir until homogeneous phase is obtained; and sequentially carrying out strong scavenging and ultrasonic cleaning on an inactivated denitration catalyst module, soaking the module in cleaning solution for 18-25 minutes, continuing soaking the module in the regeneration solution for 25-40 minutes, taking out the denitration catalyst module and drying. After the denitration catalyst regeneration solution and the catalyst regeneration method are adopted, the activity of the inactivated denitration catalyst can be efficiently recovered, and the temperature range of the catalyst activity is widened.

The invention relates to an Edaravone crystal form and a preparation method thereof. The Edaravone crystal form is characterized by X-ray diffractogram of powder. The crystal form can obviously improve the water solubility of Edaravone, thereby being more beneficial to preparation of injections. Besides, related substances are further decreased, and the safety of the preparation is improved.

The present invention obtains one kind of coarse red glossy ganoderma polysaccharide product and two kinds of single red glossy ganoderma polysaccharide products. Red glossy ganoderma sporophore powder is processed through the steps of water extraction, concentration, centrifugating after adding ethanol to obtain supernatant liquid, adding ethanol and centrifugating to obtain the precipitate as the coarse red glossy ganoderma polysaccharide product with molecular weight 4000-6000. The coarse product is dissolved in water and eluted in boric acid type ion exchange column with distilled waterand 0.05 mol/L boric acid solution successively and the first effluent and the second effluent are collected separately, dialyzed and freeze dried to obtain single red glossy ganoderma polysaccharideproducts GLPL1 and GLPL2 of average molecular weight 4100 and 5700 separately. All the products has tumor growth inhibiting effect and may be used in preparing antitumor medicine.

The present invention discloses a special wood modifier and a preparation method thereof. The special wood modifier comprises the following components, by weight, 500-800 parts of formaldehyde, 20 parts of urea, 200-400 parts of a phenol compound, 150-300 parts of organosilicon, 5-30 parts of an alkali catalyst, and 10-50 parts of an additive, wherein the formaldehyde is an aqueous solution with a mass concentration of 35-37%. According to the present invention, the special wood modifier mainly comprises a low molecular weight modified phenol formaldehyde resin, has characteristics of low viscosity, good water solubility, good storage stability, simple synthesis process, and low formaldehyde emission, and is applicable for modifications of various tree species, especially for modifications of fast-growing wood so as to provide high economic values; and density, size stability, hardness, water resistance and corrosion resistance of a base material can be substantially improved after the wood is treated by the special wood modifier.

The invention discloses a preparation method of a water-based high flash aluminum pigment for automobiles. The method comprises the steps of putting spherical aluminum powder, steel balls as grinding mediums, environmentally friendly solvent oil, oleic acid or erucic acid, and a surfactant into a ball mill, sealing the ball mill, performing ball milling, discharging with the environmentally friendly solvent oil, conveying the materials into a vibrating sieve through a pipeline to sieve, removing screen tailings, performing filter pressing to obtain filter cakes with the solid content being of 80 percent, putting the filter cakes and alcohol or ether solvents with good water compatibility into a reactor for mixing and dispersing, sealing the reactor, increasing the temperature under the protection of inert gases, then dropping water-soluble high polymer monomers and azo-initiators, increasing the temperature after the dropping is finished, holding the temperature, discharging, and performing filter pressing to obtain finished products. The method has the advantages that the environmental protection effect is good; the coating is tight, and a coating layer is difficult to be damaged; the water solubility is good, and the pigment can be directly diluted with water; and the pigment is easy to dissolve in water-based automobile paint systems, and is beneficial to the dispersion of the aluminum pigment.

The invention relates to an ellagic acid supramolecular combination and a preparation method. The substance is an anti-oxidant and has the anti-cancer effect, and the ellagic acid supramolecular combination belongs to the technical field of drugs and health care products. The ellagic acid supramolecular combination is composed of raw materials according to the following weight ratio that ellagic acid: cyclodextrin: emulsifier is equal to 1: (1-50): (0-10). The ellagic acid, the cyclodextrin and the emulsifier are added into a colloid mill, and the ellagic acid supramolecular combination is prepared by grinding and drying. The combination has the advantages of higher solubility, high dissolution rate, good stability and higher relative bioavailability.

The invention provides a water-based self-initiating visible light curable resin, and a preparation method and application thereof. The water-based self-initiating visible light curable resin has a structure as shown below in the specification, wherein R is HC=CH; R' is CH2CH(CH3) or (CH2CH2O)P; R'' is (CH2)4 or a benzene ring which is in ortho-position connection with a molecular chain; X is a residue formed after an esterification reaction is performed on hydroxyl of pentaerythritol triallyl ether; Y is a residue formed after an esterification reaction is performed on carboxyl of cinnamic acid; and m/n=1/2.5-2.5/1, s/n=1/2.5-2.5/1, m/s=1/2.5-2.5/1, (m+s)/n=1/5-5/1, and X/Y=1/5-5/1. The preparation method comprises the following steps: mixing dibasic acid, dibasic alcohol and urea; performing a heating reaction at 160-210 DEG C in a nitrogen protective atmosphere for 200-600 minutes; then removing the moisture through distillation; adding the pentaerythritol triallyl ether, and performing a heating reaction at 160-210 DEG C for 60-120 minutes; adding the cinnamic acid, and performing a heating reaction at 160-210 DEG C for 60-120 minutes; and performing cooling. The unsaturated polyester-urea resin provided by the invention has a self-initiating property, also has water solubility and a visible light curing property, and is used for preparation of a water-based self-initiatingvisible light curable paint.

The invention discloses a turmeric pigment-metal ion complex made by reaction of turmeric pigment and metal salt in any one or mixed solvent of alcohol solvent and acetone. It also discloses the making method and the application of making drugs to cure tumor or hepatitis. It can largely improve the water-solubility and stability of the turmeric pigment and be made into many solvents such as oral preparation and injection, etc.

The invention relates to the field of medical chemistry and pharmacotherapeutics, specifically, the invention relates to an aniline quinazoline derivative, the preparation method and the use thereof shown in the following general formula I. The side chain of the aniline quinazoline derivative provided by the invention comprises various pyrrolidine rings; compared with Iressa, the derivative has stronger cytotoxic activity to tumor cell lines and is a promising antitumor medicine.

The present invention is production process of water soluble ginkgo leaf extract. Ginkgo leaf GBE coarse product as material is produced into the generation-V GBE through extraction with pure water or solvent in a lixiviation apparatus, letting stand, filtering, precipitating with water solution of gelatin, filtering, filtering, vacuum concentrating to dry, dissolving in anhydrous alcohol, filtering, vacuum concentrating, drying and crushing. The production process is simple, high and stable in product quality and low in product cost, and produces no toxic matter and waste, and the product is non-toxic, reliable, high in quality and high in water solubility.

The invention discloses salicylic acid-g-chitosan oligosaccharide graft and the synthetic method thereof. The salicylic acid-g-chitosan oligosaccharide graft, the general structure of which is shown in formula (I), is prepared from alicylic acid and chitosan oligosaccharide by graft polymerization. The molecular weight of chitosan oligosaccharide is 1-100kDa and the deacetylation degree thereof is 70%-100%. A part of amino groups on chitosan oligosaccharide chain in the salicylic acid-g-chitosan oligosaccharide graft are replaced by salicyl, and the substitution degree of the amino group is 1%-80%. The synthetic method is simple and convenient for post-treatment. The prepared salicylic acid-g-chitosan oligosaccharide graft employs hydrotropic compound salicylic acid as the hydrophobic part and chitosan oligosaccharide as the hydrophilic part to form salicylic acid-g-chitosan oligosaccharide micelle as an insoluble drug carrier in an aqueous medium by self-aggregation, thereby the administering means is greatly enriched and the curative effect is improved.

The invention relates to a method for preparing an origanum oil-beta-cyclodextrin inclusion compound feed additive. The origanum oil-beta-cyclodextrin inclusion compound feed additive is prepared by carrying out clathration on origanum oil and beta-cyclodextrin according to a mass rate of 1: (5-7) through a coprecipitation method. The origanum oil-beta-cyclodextrin inclusion compound feed additive prepared by using the method has improved water solubility and can be directly added with water for being drunk by livestock and poultry. After an inclusion compound is prepared, drug molecules of the origanum oil are prevented from being in contact with the surrounding environment to a certain extent and are avoided being influenced by light, oxygen and hydrolysis conditions, so that the stability of the drug molecules of the origanum oil is improved, the volatilization of the drug molecules of the origanum oil is reduced, the drug effect and the retention period of the origanum oil-beta-cyclodextrin inclusion compound feed additive are prolonged, the stability of a product is improved, the bioavailability is improved and the using effect is obviously strengthened. The origanum oil-beta-cyclodextrin inclusion compound feed additive can be mixed into a livestock feed for use and can also be used as a drinking agent.

The invention relates to a fluorescent probe for detecting hypochlorite aions. A preparation method of the fluorescent probe comprises the steps of refluxing and reacting fluorescein and hydrazine hydrate in ethanol to generate fluorescein hydrazide; then reacting fluorescein hydrazide with phenyl isocyanate in N,N-dimethyl formamide at a room temperature, and purifying by silica gel column chromatograph to obtain a fluorescein amide phenylurea fluorescent probe. The fluorescent probe has good water-solubility, fast reaction time and high selectivity, has high specificity for the hypochlorite aions, can work at a physiological environment condition with a pH value of 7.4, and has prospects for applications in bioluminescent imaging.

The invention discloses glass fiber air filter paper with an antibacterial property. The glass fiber air filter paper comprises alkali-free glass fibers of which the diameter is 0.1-0.5 micron, alkali-free glass fibers of which the diameter is 1.0-2.0 microns, alkali-free glass fibers of which the diameter is 5-7 microns, glass fiber filter paper manufactured from PET (polyethylene terephthalate) polyester fibers, and a pyrithione derivative antibacterial layer which is attached to the surface of the filter paper. The invention also discloses a method for preparing the glass fiber air filter paper, comprising the following steps of: (1) selecting raw materials according to a mixing ratio; (2) pulping and dispersing the raw materials to obtain a slurry; (3) diluting the slurry and adjusting the PH value; (4) removing residues from the slurry obtained in the step (3), and preparing wet paper by using a wet method forming; (5) dehydrating the wet paper obtained in the step (4); (6) passing the wet paper obtained in the step (5) through a gum solution of a pyrithione derivative; and (7) drying the wet paper obtained in the step (6). The glass fiber air filter paper is excellent in antibacterial and air filtration performances, and is wide in application field.

The invention relates to a preparation method for a fatty acid derivate cation asphalt emulsifying agent. According to the method, an oil material containing 45-75% of linoleic acid is adopted as a raw material; normal pressure hydrolysis is performed to obtain a mixed fatty acid; the mixed fatty acid reacts with an olefinic acid or an anhydride to obtain a dicarboxylic acid intermediate or a tricarboxylic acid intermediate; the dicarboxylic acid intermediate or the tricarboxylic acid intermediate reacts with a mixed amine with different types to prepare the fatty acid derivate cation asphalt emulsifying agent with characteristics of strong surface activity and small critical micelle concentration. According to the present invention, the preparation method is simple; the raw material is easy to obtain; the prepared fatty acid derivate cation asphalt emulsifying agent has good water solubility, the water solution of the fatty acid derivate cation asphalt emulsifying agent has low surface tension, the critical micelle concentration range is 0.01-0.05 wt.%, the concentration for formation of the micelle is low, and the surface activity is strong; the emulsifying agent of the present invention is used for emulsifying the asphalt, the obtained cation asphalt is the medium breaking type asphalt or the slow breaking type asphalt, has characteristics of fine and uniform particles, and good storage stability, and has wide applicability.

The invention relates to a covalent polycompound of water-soluble polysaccharide and taxane, and a preparation method and medical application of the covalent polycompound. The method disclosed by the invention comprises the following step: connecting the taxane compound to the water-soluble polysaccharide through a covalent bond by adopting selective protection and selective deprotection methods and a plurality of degradable structure units, so as to obtain the covalent polycompound which can retain the biological activity of the taxane compound and is relatively simplex in structure. The novel covalent polycompound is good in water solubility, and can replace an existing clinical taxane preparation free of a cosolvent with toxic and side effects.

The invention provides tetrandrine organic acid salts. White citric acid tetrandrine salt crystal is prepared through adding tetrandrine to citric acid solution to carry out salt-forming reaction, and drying the obtained tetrandrin citric acid salt solvent. The invention is proved through pharmacological test to have wider and stronger antineoplastic activity, and is proved through in-vitro cell culture system and animal test to have no obvious toxic or side effects on cell growth of a normal person and a tested animal with effective antineoplastic dosage, and have good safety, good water solubility and pH value approximate to the physiological status of human blood, thereby facilitating the improvement on bioavailability and drug action. The tetrandrine organic acid salts can be applied to preparing medicine for treating neopastic diseases. The preparation method has the advantages of simple and feasible process, high success ratio and low cost, and is applicable to scale production. The structural general formula of the tetrandrine organic acid salts is shown as the above.

The invention discloses a preparation method of a water-soluble chitosan-base aggregation-induced light-emitting fluorescent probe, which mainly comprises the following steps: marking a tetraphenyl ethylene (TPE) fluorescent molecule to a chitosan chain to obtain TPE-CS; and carrying out succinylation modification on the TPE-CS by using an acetic acid/methanol mixed solvent system to obtain the TPE-N-CS. The fluorescent probe has favorable water solubility and aggregation-induced light-emitting characteristic, and has the advantages of high sensitivity, favorable light stability, no quenching under high-concentration conditions, no fluorescence spectrum drift, favorable imaging effect and the like as compared with the traditional fluorescent probe. The fluorescent probe is hopeful to be applied to the fields of cell tracing, drug metabolism detection, environmental monitoring and the like.