110 results about "Aluminum hydroxide gel" patented technology

A high integrity liposome comprising at least one stabile lipid and at least one peptide-like therapeutic agent associated with said liposome, adapted for parenteral administration to an animal, including a human, and method according to manufacture and use. Immunizing dosage forms comprising a liposome and an immunogen, wherein said liposome and immunogen are present in an immunization dose. Additionally, a dosage form, including such form particularly adapted to producing an immune response, comprising a salt according to an organic acid derivative of a sterol and an immunogen wherein said organic acid derivative of a sterol and immunogen are present in an immunization dose, and method according to use is disclosed. Further, a dosage form, including such form particularly adapted to producing an immune response, comprising dimyristoylphosphatidylcholine (DMPC)/cholesterol liposomes, optionally in an aluminum hydroxide gel, and an immunogen wherein said DMPC/cholesterol and immunogen are present in an immunization dose, and method according to use.

The invention discloses a polymeric aluminum sulfate synthesis method and discloses a preparation method of a novel alkali-free liquid accelerator based on synthesis of polymeric aluminum sulfate. According to the alkali-free accelerator, an aluminum sulfate solution is neutralized by ammonia water, active aluminum hydroxide gel is prepared, active aluminum hydroxide is filtered, dried and ground into powder, then the aluminum sulfate solution is added, and the polymeric aluminum sulfate is prepared. The alkali-free accelerator comprises, in percentage, 45%-55% of the polymeric aluminum sulfate, 0%-5% of inorganic acid, 0%-2% of a stabilizer, 0%-2% of an organic early strength agent, 0%-2% of an organic tackifier and the balance of water. The cement setting time and the colloidal mortar strength of the accelerator can meet the requirement of first-class accelerators for JC477-2005 sprayed concrete under the condition of the lower mixing amount, and meanwhile, the accelerator is an alkali-free liquid accelerator and can effectively avoid adverse effects caused by excessively high alkali content. The cement types of the accelerator have good adaptability.

The invention discloses a zirconia-alumina composite oxide carrier and a method for preparing the same. The carrier is prepared from a zirconium hydroxide-aluminum hydroxide gel serving as a raw material by using a super-solubility micelle method. Because the gel contains a surfactant and hydrocarbon components, zirconia nanoparticles and alumina nanoparticles formed after dehydration of polymerized zirconium hydroxide and aluminum hydroxide still have rod-like basic structures after shaping and roasting, and the nanoparticles are disorderly stacked into a frame structure. The carrier has large pore volume, large aperture, high porosity, large orifices on outer surface and high pore penetrability, and particularly for high molecules, the carrier can prevent a catalyst from becoming inactivated due to blockage of the orifices, contribute to increasing the deposition of impurities and prolong the operating period of the catalyst because the carrier does not have orifices similar to ink bottle-shaped orifices. The carrier can be used in catalytic reactions comprising high molecular reactants or products.

The invention discloses a preparation method of an aluminum-coated spherical lithium nickel cobalt aluminum oxide cathode material for a lithium-ion battery. The method comprises the following steps: firstly, dissolving an aluminum salt into water, and adding ammonia water to obtain sediments; dispersing the sediments, adding nitric acid to peptize the sediments, and ageing the product to obtain aluminum hydroxide gel; adding a nickel-cobalt mixed metal salt solution and the aluminum hydroxide gel, adding a complexing agent and a precipitant for reaction, and carrying out suction filtration, washing and drying to obtain inner spherical nickel cobalt aluminum hydroxide precursor powder; dispersing the precursor powder, carrying out precipitation with an aluminum salt solution and ammonia water and preparing an aluminum-coated spherical nickel cobalt aluminum precursor; mixing a lithium source and the aluminum-coated spherical nickel cobalt aluminum precursor evenly; and sintering the mixture, so as to obtain aluminum-coated spherical lithium nickel cobalt aluminum oxide powder. The nanoscale aluminum-coated lithium nickel cobalt aluminum oxide material with a constant crystal structure is prepared; and the lithium nickel cobalt aluminum oxide material with high tap density, high specific capacity and excellent cycle performance is obtained.

The invention discloses a modified aluminum oxide carrier and a preparation method thereof. The modified aluminum oxide carrier is prepared from aluminum hydroxide gel serving as a raw material by the steps of introducing an auxiliary agent before and/or after drying, and then forming, drying and roasting, wherein the aluminum hydroxide gel is prepared by a molten salt super-solubilizing micelle method. In the preparation process of the carrier, the aluminum hydroxide gel comprises a surfactant and a hydrocarbon component, so after the processes of forming and roasting, nano-aluminum oxide particles formed by dehydrating polymerized aluminum hydroxide still have bar-shaped basic structures and are stacked into a frame structure out of order; and the properties of a catalyst are further improved by adjusting the acidity of the carrier and the interaction between an active metal and the carrier through the auxiliary agent. The carrier has the advantages of large pore volume, large aperture, high porosity, larger orifice on the outer surface, high pore canal penetrability, favorability for increasing deposition of impurities and capacity of prolonging the running period of the catalyst.

The invention discloses a liquid alkali-free setting accelerator. The liquid alkali-free setting accelerator contains a complex, an Al-MOF (aluminum-containing metal-organic framework), aluminum hydroxide colloids, an organic tackifier and an auxiliary, wherein raw materials of the complex comprise polyaluminum sulfate and a complexing agent, the organic tackifier contains resin, and the resin contains epoxy vinyl ester resin. The invention further provides a preparation method of the liquid alkali-free setting accelerator. The preparation method comprises steps as follows: (1), polyaluminum sulfate and the complexing agent are subjected to a complex reaction, and the complex is prepared; (2), the complex and the Al-MOF are mixed and subjected to physical and chemical reactions, and a high-dispersion complex is obtained; (3), the high-dispersion complex, aluminum hydroxide gel, the organic tackifier and the auxiliary are stirred and mixed, and the liquid alkali-free setting acceleratoris prepared.

The invention belongs to the field of biomedicine, and particularly relates to an aluminum hydroxide gel-polysaccharide composite immunologic adjuvant and a preparation method and application thereof. The invention aims to provide a new immunologic adjuvant with good performance. The technical scheme is to provide a composite immunologic adjuvant. The composite immunologic adjuvant mainly contains aluminum hydroxide gel and polysaccharide serving as bacteria source. The aluminum hydroxide gel-polysaccharide composite immunologic adjuvant provided by the invention has the advantages of strong immunocompetence, high clinical safety and the like, and is an excellent composite immunologic adjuvant aiming at various antigens. The hepatitis vaccine and tumor vaccine prepared by taking the aluminum hydroxide gel-polysaccharide composite provided by the invention as adjuvant has stronger immune effect and anti-cancer effect, and thus new selection is provided for the development and application of vaccine.

The invention discloses a method for preparing a high-purity human coagulation factor VIII from a cryoprecipitate of a human plasma fraction. The method comprises the following steps: (1) cryoprecipitate dissolution; (2) aluminum hydroxide gel adsorption and filter pressing; (3) S/D virus inactivation; (4) anion exchange resin column chromatography; (5) hydrophobic column chromatography; (6) ultrafiltration dialysis and concentration; (7) addition of one or more stabilizers and titer adjustment; (8) nano-membrane virus-removing filtration; (9) sterile filtration and sub-packaging; (10) freeze-drying; (11) dry-heat virus inactivation. The method has the advantages that a human coagulation factor VIII is purified through the two column chromatography steps, so that the prepared high-purity product can reach a specific activity of about 300 IU/mg, considerably higher than about 50 IU/mg in the prior art, and the product appearance and the heat stability are obviously improved; in the preparation process, three virus removing modes are adopted, so that the clinical use safety of the product can be greatly improved.

The invention relates to a method for preparing a nano aluminum hydroxide gel adjuvant, belonging to the technical field of processes for preparing immunologic adjuvant of biological products for animals. The method comprises the following steps: mixing an aluminum salt solution and a soda solution which serve as raw materials, and adding a certain amount of stabilizing agent during mixing; shearing by a high-shearing emulsifying machine to obtain the nano aluminum hydroxide solution preliminarily; precipitating, washing and re-precipitating to obtain nano aluminum hydroxide gel; preparing a solution from the nano aluminum hydroxide; and compounding the solution with an inactivated bacterial solution to obtain an inactivated vaccine. The nano aluminum hydroxide gel adjuvant prepared by adopting the method is uniform in particle size distribution, has high purity, strong adsorbability and no side effect and has a good application prospect in the aspect of preparation of immunologic adjuvant.

The invention relates to a preparation method of high-heat stable rare-earth modified alumina, comprising the following steps of: 1) reacting pseudoboehmite by nitric acid to generate aluminum sol; 2) taking soluble salt of lanthanum, adding de-ionized water to prepare aqueous solution with the concentration of 100-260g/l; 3) taking the aluminum sol and the soluble salt solution of the lanthanum, and mixing according to the mass ratio of Al2O3 to La2O3 being at 94-97 to 3-6 to obtain modified aluminum sol; 4) uniformly mixing an organic high polymer modifier with 2-6mol of an alkaline precipitator according to the mass ratio 5-10 to 90-95 to obtain a modified alkaline precipitator; 5) mixing the modified aluminum sol with the modified alkaline precipitator, performing co-precipitation; 6) performing vacuum filtration on a modified aluminum hydroxide gel precipitant, and washing; 7) calcining the precipitant in a muffle furnace; and 8) breaking the calcined matter obtained in the step 7) to obtain a modified alumina coating material. The preparation method of the high-heat stable rare-earth modified alumina is simple in steps, and the prepared modified alumina has good high-heat stability.

The invention relates to an aluminum hydroxide gel. The preparation method includes performing reaction of aluminum nitrate hydrate and ammonia water to obtain aluminum hydroxide, adding additive to suspension after ball-milling to obtain aluminum hydroxide gel, and drying to obtain aluminum hydroxide dried gel; and grinding and calcining the aluminum hydroxide dried gel to prepare microlite alpha-Al2O3 aggregate. The preparation method is suitable for large-scale production of the microlite alpha-Al2O3 aggregate, conditions of process are easy to control, grain size of primary grain of the prepared microlite alpha-Al2O3 aggregate is 50-400nm, particle size of secondary aggregate particle of the prepared microlite alpha-Al2O3 aggregate is 75-600um, the prepared microlite alpha-Al2O3 aggregate is compact in structure, density is 3.90-3.98g/cm<3>, and hardness is 19-24GPa. The prepared microlite alpha-Al2O3 aggregate can be used for abrasive, high-temperature-resistant material, electronic device material, high-frequency insulation material, aerospace material, information material and the like.

The invention discloses a preparation method of high-purity aluminum oxide. The preparation method comprises the following steps of: with industrial Al2(SO4)3.18H2O and (NH4)2SO4 solids as raw materials, preparing an aluminum ammonium sulfate crystal by utilizing a recrystallization method; adding ammonia water to the obtained aluminum ammonium sulfate crystal to obtain an aluminum hydroxide gel; purifying with an aluminum-type mixed resin to obtain a high-purity aluminum hydroxide gel; distilling the obtained aluminum hydroxide gel at reduced pressure to obtain aluminum hydroxide colloidal particles; roasting the aluminum hydroxide colloidal particles for 1 to 2 hours at 1,000 to 1,200 DEG C through a muffle so as to obtain aluminum oxide powder. According to the preparation method, the aluminum ammonium sulfate crystal is prepared by utilizing the recrystallization method, so that the crystal has less impurity; and the prepared aluminum hydroxide sol is purified by the ion exchange resin to obtain the high-purity aluminum hydroxide gel, and then the high-purity aluminum hydroxide gel is roasted to obtain the aluminum oxide which is high in purity.

The invention discloses a method for removing bacterial endotoxin in a protein solution. The method comprises the following steps of S1, preparing aluminum hydroxide gel, namely adding 2mol/L sodium hydroxide into 4.5% of aluminum chloride solution to obtain a solution with the pH value of 7.0-7.5, reacting at the temperature of 2-8 DEG C for 1-2 hours, and centrifugally collecting gel at the speed of 4000rpm; and S2, removing bacterial endotoxin in the protein solution, adding the aluminum hydroxide gel prepared in the step S1 into the protein solution, stirring at the temperature of 4 DEG C and the speed of 100rpm for 1.5-2.5 hours, and centrifugally collecting at the speed of 4000rpm to obtain a supernatant solution without endotoxin. According to the method, electrostatic adsorption is mainly used as the way of adsorbing proteins by using the aluminum hydroxide gel, the adsorption of aluminum hydroxide to the proteins can be reduced or avoided when phosphate radicals and high-concentration NaCl (contained in a PB buffer solution) exist, and 99% of bacterial endotoxin can be removed by using the buffer solution.

The invention discloses a method for synthesizing highly dispersed aluminum orthophosphite crystals from an aluminum salt and hypophosphorous acid. The method is characterized in that the method comprises the following steps: (1) using the aluminum salt to prepare an aluminum hydroxide gel, filtering and washing till a washing solution has no anions of the aluminum salt; (2) adding distilled water into the gel after washing, stirring to get an aluminum hydroxide sol, adding the sol into the hypophosphorous acid while stirring, and continuously stirring to realize full reaction after dripping; and (3) filtering and heating an obtained solution, separating out aluminum orthophosphite, filtering, and drying to get the uniform and well-dispersed aluminum orthophosphite crystals. Compared with the prior art, the method disclosed by the invention has the advantages of simple process, energy conservation, environmental protection, high product yield and purification and short production period, and is suitable for industrial production.

The invention discloses a preparation method of a boron-containing alumina carrier. The method comprises the following steps of: gelling the conventional aluminum hydroxide; adding into a stable boron-containing organic compound solution; aging, filtering, washing and drying to obtain dry boron-containing aluminum hydroxide gel; mixing and molding with an adhesive; and heating and performing gradual programmed heating and baking to obtain the boron-containing alumina carrier. Boron-containing alumina is a high-performance carrier component, which can be used for providing a large pore volume and a large specific surface area, has an appropriate pore structure and acidity, and is particularly suitable for a catalyst material needed by a heavy hydrocarbon catalytic processing process.

The invention relates to the technical field of preparation methods of aluminum hydroxide flame retardants, in particular to a method for preparing a high-purity superfine aluminum hydroxide flame retardant by a decomposition method. The production process of the aluminum hydroxide flame retardant comprises the following steps: (1) preparation of an aluminum hydroxide seed crystal: cooling a Bayerprocess or sintering process sodium aluminate refined solution, and carrying out carbon decomposition in a carbon decomposition tank to form a gel-like aluminum hydroxide gel slurry; (2) preparationof aluminum hydroxide slurry through decomposition: adding the gelatinous aluminum hydroxide glue solution prepared in the step (1) into a Bayer process or sintering process sodium aluminate refined solution, and stirring and decomposing the mixture in a seed precipitation tank to obtain ultrafine aluminum hydroxide slurry; (3) solid-liquid separation on the aluminum hydroxide slurry: separating the superfine strong aluminum oxide glue solution prepared in the step (2) through a filter to obtain a filter cake; and (4) drying: carrying out paddle type drying and rotary flash evaporation drying.The purity of the aluminum hydroxide flame retardant prepared by the preparation method is not lower than 99%, the whiteness is not lower than 98%, and the average particle size is 1-2 [mu] m.

The invention relates to flame retardant polyurethane hard foam plastic for exterior wall external insulation and a preparation method thereof, belonging to the technical field of thermal insulation materials for buildings. The preparation method of the flame retardant polyurethane hard foam plastic for exterior wall external insulation provided by the invention comprises the following steps: first, uniformly mixing all components except PAPI (Polymethylene Polyphenylisocyanate), wherein in the mixing process, metal alkoxide and water are reacted to generate a nano aluminum hydroxide gel in situ, other products are alcohols corresponding to the metal alkoxide, and no other byproducts are brought to a polyether system; then, adding PAPI, stirring, and after stirring, pouring and foaming to obtain the flame retardant polyurethane hard foam plastic provided by the invention.

Disclosed are a combined vaccine for hepatitis A and hepatitis E, and preparation method thereof. Said vaccine comprises hepatitis E virus recombined peoteins, hepatitis A attenuated live vaccine and hepatitis A inactivated vaccine. Said method comprises before the paretion of the final combined vaccine, absorbing hepatitis A attenuated live vaccine viruses and/or hepatitis A inactivated vaccine viruses on aluminum hydroxide gel, absorbing hepatitis E virus recombined peoteins on aluminum hydroxide gel, adjusting the pH value of the two compositons, and mixing the two compositons together. The inventiion is provided with convenience, multiple-effect, low cost, and effective prevention of hepatitis A and hepatitis E for human and animals.

The invention discloses a method for synthesizing a polyaluminum sulfate chloride water purifier by using aluminum foil corrosion waste acid and waste aluminum. The product is extensively applied to purifying drinking water and industrial water and treating sewage. The method comprises the following steps: adding the waste aluminum into the aluminum foil corrosion waste acid, filtering after sufficiently reacting, adding ammonia water into filtrate to regulate the pH value of the filtrate, and thereby obtaining aluminum hydroxide gel; adding the aluminum hydroxide gel and the aluminum foil corrosion waste acid into a reactor for heating, stirring, polymerizing, curing and re-crystallizing to prepare the polyaluminum sulfate chloride water purifier. According to the method disclosed by the invention, the aluminum foil corrosion waste acid comprises useful ingredients of Al<3+>, SO4<2->, Cl<-> and the like which are used for synthesizing the polyaluminum sulfate chloride, and the polyaluminum sulfate chloride water purifier can be synthesized through the design, so that the resources are effectively utilized to solve a waste acid treatment problem, the purpose of using waste to treat waste is achieved, and social significance and economic significance are achieved.

The invention discloses universal environment-friendly building glue which comprises the following raw materials in parts by weight: 30-60 parts of an epoxy resin, 30-60 parts of an acrylic resin, 6-14 parts of aluminum hydroxide gel, 5-12 parts of xanthan gum, 10-16 parts of glycerin, 5-10 parts of polyethylene glycol, 3-6 parts of sodium dodecyl benzene sulfonate, 6-12 parts of sodium carboxymethylcellulose, 2-4 parts of dibenzylidene sorbitol, 0.5-2 parts of an antioxidant, 1-4 parts of a water retaining agent, 2-8 parts of a stabilizer, 3-5 parts of a nucleating agent, 2-6 parts of an anti-mold agent, 32-56 parts of ethanol and 16-28 parts of water. A preparation method of the universal environment-friendly building glue comprises the following steps: preparing a resin solution, preparing an ethanol-water mixed solution, and mixing with other materials. The building glue disclosed by the invention is reasonable in formula, low in cost, good in transparency, good in adhesive property, good in peaceability, good in environmental-friendliness, short in curing time, simple in preparation method, low in equipment requirement, high in production speed and high in raw material utilization rate.

The invention discloses a boron-containing aluminum hydroxide solid elastomer and the preparation method thereof. In the method, a stable solution of boron-containing organic compounds is added to conventional aluminum hydroxide gel, and the mixture is aged, filtered, washed and dried to obtain boron-containing aluminum hydroxide solid elastomer. The boron-containing aluminum hydroxide solid elastomer of the invention is a carrier ingredient with excellent performance, can provide large pore volume and large specific surface area, possesses suitable pore structure and acid property, and is especially suitable for being used as the catalyst material required in catalysis and process of heavy hydrocarbon.