26results about How to "The preparation method is simple and easy" patented technology

The invention relates to lysosome-based nano drug-loaded particles and application thereof, and belongs to the technical field of biological medicines. According to the invention, the lysosome membrane is used as a biomimetic membrane source to coat the surface of the drug nanoparticle, so that the structure stability of the lysosome membrane is maintained, and the activity of hydrolase which naturally exists is retained to the greatest extent, so that the drug-loaded nanoparticle can perform in-situ degradation on an extracellular matrix of a tumor tissue in an in-vivo delivery process; therefore, the physical barrier of the tumor tissue is effectively weakened, the permeation, distribution and cellular uptake ability of the nano-drug in the tumor tissue are remarkably enhanced, the condition that immune cells enter the tumor tissue is improved on the basis, and finally the tumor treatment effect is improved.

Provided are a porous membrane and a method for producing the porous membrane, whereby the pore diameter can be reduced and the flow rate can be increased. A porous film containing (A) at least one resin component selected from the group consisting of a polyimide, a polyamideimide, and a polyethersulfone, and a solvent (S), in which the solvent (S) contains a nitrogen-containing polar solvent (S1) having a boiling point at atmospheric pressure of 200 DEG C or higher, and the content of the nitrogen-containing polar solvent (S1) in the porous film is 10 ppm to 2000 ppm (inclusive).

The purpose of the present invention is to provide a magnetic recording medium which stably maintains a state in which a granular magnetic layer forms a granular structure therein, and which improves the surface recording density. The magnetic recording medium has a substrate, an underlayer, a first magnetic layer, and a second magnetic layer in this order, the first magnetic layer including magnetic particles having an L10 structure, and the second magnetic layer including magnetic particles having an L10 structure and having a granular structure including a grain boundary portion of hexagonal boron nitride. The (111) plane of the magnetic particles contained in the first magnetic layer is covered with an alloy of VN, Si3N4, YN, or TiN at the interface with the second magnetic layer, and the magnetic particles contained in the second magnetic layer are epitaxially grown from the (001) plane of the magnetic particles contained in the first magnetic layer. The magnetic particles contained in the first magnetic layer and the magnetic particles contained in the second magnetic layer are each columnar crystals penetrating the first magnetic layer and the second magnetic layer.

The invention relates to a micromechanical component for a stress sensor, having a first substrate (10) with a first substrate surface (10a), a second substrate (12) with a second substrate surface (12a) and an evaluation electronics (20) configured at and / or in the second substrate (12), wherein the first substrate (10) is fixed at the second substrate (12) by means of at least one electrical connection (22) formed by means of a metal bonding method, which is configured in an intermediate volume (14) between the first substrate surface (10a) and the second substrate surface (12a), wherein at least one electrode (16, 16a, 16b, 62) and at least one counter electrode (18a, 18b, 18c) are arranged in the intermediate volume (14), wherein the at least one electrode (16, 16a, 16b, 62) and / or the at least one counter electrode (18a, 18b, 18c) are electrically connected at the evaluation electronics (20) by means of the at least one electrical connection (22) formed by means of a metal bonding method.

The invention discloses a metal ion functionalized NT-proBNP photoelectrochemical sensor and a preparation method, and belongs to the technical field of photoelectrochemical biosensors, the photoelectrochemical sensor comprises a Fe < 3 + >-coated BiVO4 electrode, and the preparation method of the electrode comprises the following steps: dispersing BiVO4 in deionized water, adding excessive Fe < 3 + > for adsorption, removing the excessive Fe < 3 + > after the adsorption is finished, and obtaining the metal ion functionalized NT-proBNP photoelectrochemical sensor. And then dispensing the Fe < 3 + >-coated BiVO4 on a conductive material, so as to obtain the Fe3 +-coated BiVO4 / Fe3 +-coated BiVO4 / Fe3 +-coated BiVO4 composite material. When the photoelectrochemical sensor provided by the invention is used for NT-proBNP detection, no trapping agent or bias voltage needs to be applied, measurable signal output is realized through enzyme-linked immunosorbent assay, and the detection scheme has good selectivity and stability, can realize accurate detection of NT-proBNP, and has good application prospects in clinical diagnosis.

Embodiments of the present invention provide a semiconductor memory device and a manufacturing method of the semiconductor memory device, which can realize an increase in the number of contacts and miniaturization of a contact portion. A semiconductor memory device according to an embodiment of the present invention includes a memory cell array and a contact portion. The memory cell array is formed by three-dimensionally arranging memory cells on a laminate, which has a plurality of unit layers including a group of a conductive layer and an insulating layer. The contact portion connects the memory cell array and the conductive layer and a contact. The contact portion has a descending step portion and an ascending step portion. The descending step portion has a plurality of step portions that are sequentially stepped in a first direction away from the memory cell array. The ascending step portion is adjacent to the descending step portion in a second direction orthogonal to the first direction. The ascending step portion has a plurality of step portions that are sequentially stepped in the first direction. The contact arranged at the step portion of the descending step portion and the contact arranged at the step portion of the ascending step portion are arranged in the second direction.

This invention discloses a method for manufacturing a traveling wave pump rotor, comprising the following steps: machining the outer shell, machining the base plate and the first injection-molded plate, machining the cover plate and the second injection-molded plate, machining the enclosure mechanism, and machining and forming the rotor. The manufacturing method of this invention is simple in its steps, which not only improves the integral machining quality of the traveling wave pump rotor, but also facilitates the formation of an injection-molded layer on the surface of the traveling wave blades, reducing friction and wear of the traveling wave pump rotor during operation, while also reducing noise and extending the service life of the traveling wave pump.

The invention relates to a culture medium for culturing human mycoplasma pneumoniae and a culture method, and belongs to the technical field of microorganisms, the culture medium for culturing the human mycoplasma pneumoniae comprises a mycoplasma culture medium and a growth promoting additive, the growth promoting additive comprises horse serum or fetal calf serum, cholesterol, penicillin sodium and an HEPES buffer solution, according to the culture medium for culturing the human mycoplasma pneumoniae, various components are simple and easy to obtain, the preparation method of the culture medium is greatly simplified, and the efficiency is improved; according to the culture method of the human mycoplasma pneumoniae, the culture mode is changed from a static state to a dynamic state, so that the culture efficiency of the human mycoplasma pneumoniae is improved, and meanwhile, the thallus yield of the human mycoplasma pneumoniae is also improved; the culture method for preparing the human mycoplasma pneumoniae is short in period, low in cost, high in culture viable organism density and high in yield, and is suitable for large-scale culture of the human mycoplasma pneumoniae.

The invention provides a composite peptide dietary supplement for improving yang-deficiency constitution as well as a preparation method, a preparation and application of the composite peptide dietary supplement, and belongs to the technical field of food biology. On the first aspect, the invention provides the composite peptide dietary supplement, and the composite peptide dietary supplement comprises the following raw materials: cinnamon, rhizoma zingiberis, fructus lycii, raspberry, Chinese yam, rhizoma polygonati, Chinese dates and liquorice; on the second aspect, the invention provides a preparation method of the composite peptide dietary supplement; and thirdly, the invention provides a preparation of the composite peptide dietary supplement. In the fourth aspect, the invention also provides application of the composite peptide dietary supplement and the preparation thereof in preparation of food or medicines suitable for people with yang-deficiency constitution.

This disclosure provides a rare-earth magnet with improved magnetization compared to previous methods, and a method for manufacturing the same. The disclosure relates to a method for manufacturing a magnetic magnet and a rare-earth magnet obtained by this method. The method includes: preparing a mixture containing a specified magnetic powder and a modifying material powder; mixing the magnetic powder and the modifying material powder to obtain a mixed powder; compressing the mixed powder in a magnetic field to obtain a magnetically shaped body; and sintering the magnetically shaped body under pressure to obtain a sintered body. The magnetic powder comprises a first particle group and a second particle group, where d1μm represents the particle size distribution D of the first particle group. 50 And let d2μm represent the particle size distribution D of the second particle swarm. 50 The d1 and d2 satisfy the relationship 0.350≤d2 / d1≤0.500, and the ratio of the total volume of the first particle group to the total volume of the second particle group is in the range of 9:1 to 4:1.

The present disclosure provides a polyamide resin and a preparation method therefor, a composition, and a fiber product. The polyamide comprises diamine structural units and diacid structural units, wherein 90 mol% or more of the diacid structural units are derived from adipic acid, 90 mol% or more of the diamine structural units are derived from 1,5-pentanediamine, and the polyamide resin contains a water-extractable substance in a content of 0.7 wt.% or less. The water-extractable substance has a number average molecular weight of 2000 or less. The preparation method of the polyamide resin of the present disclosure is simple without using large-scale equipment, and the process parameters thereof are easy to control, thereby facilitating mass production thereof. The polyamide resin of the present disclosure has a long spinneret wipe cycle time and less broken filament times, and the obtained fiber has less broken filaments, low yarn unevenness, less dyed dark grain, a good dyeing effect, and an excellent elongation at break, breaking strength and a lower boiling water shrinkage, a high spinning yield and a high dyeing yield.

The invention provides an amino acid composition for animals or amino acid drinking water for animals. The amino acid composition or the amino acid drinking water for animals has better animal palatability. The aqueous solution is weakly acidic, is close to the pH value of animal urine, has low sodium and low hardness, reduces the burden of kidneys, reduces the intake of mineral elements, and reduces the probability of calculus; the preparation method is simple, palatability and health management are combined, and long-term drinking can enhance the pleasure of drinking water by cats, increase the water drinking amount and reduce the incidence rate of urinary system diseases; the feed does not contain any animal-derived food calling component, and has a long shelf life.

The invention belongs to the technical field of catalyst preparation, and relates to a simple preparation method and application of a mesoporous hydrogenation catalyst carrier. The preparation method comprises the following steps: adding aluminum nitrate nonahydrate and terephthalic acid into N, N-dimethylformamide, and uniformly mixing to obtain a mixed solution A; heating the mixed solution A in a sealed state, and carrying out hydrothermal reaction; after the reaction is finished, centrifuging and washing to obtain an MIL-53 precursor; and calcining the MIL-53 precursor to obtain the mesoporous carrier. The preparation process of the mesoporous hydrogenation catalyst carrier provided by the invention does not need complex operations such as acid pickling and a template method, and the preparation method is simple in process, economical and efficient. According to the mesoporous carrier prepared by the method, the aperture can reach 20-30nm, mass transfer is more facilitated, and the catalytic activity is improved. The mesoporous hydrogenation catalyst carrier has the advantages of high mesoporous rate and high catalytic activity, can be recycled for multiple times, and provides a new thought for preparation and application of the mesoporous hydrogenation catalyst carrier.

The application discloses a self-cleaning composite piezoelectric ceramic membrane and a preparation method and application thereof, and belongs to the field of composite ceramic membranes. The application aims to solve the technical problem of poor anti-biofilm pollution effect of existing ceramic membrane separation technology. The application first prepares a barium titanate ceramic membrane as a base film, and then loads copper oxide one-dimensional nano structures on the piezoelectric ceramic substrate. Since the base film has a large membrane surface area, more catalysts can be combined, thereby providing more active sites for catalytic reaction. The composite membrane significantly improves the hydrophilicity, anti-pollution performance and piezoelectric catalytic self-cleaning performance of the membrane, can quickly and effectively separate pollutants in water, and thereby improves the flux and anti-pollution performance of the membrane.

The present application provides a kind of polypeptide sustained-release hydrogel coating for preventing catheter urinary tract infection and its preparation method, the coating includes the adhesive bottom layer attached to the surface of catheter substrate, and the polypeptide sustained-release hydrogel functional layer compounded outside the adhesive bottom layer;The functional layer includes hydrophilic hydrogel gel-forming matrix, targeted antibacterial polypeptide, polypeptide sustained-release carrier and biocompatible auxiliary agent.The present application solves the interface bonding problem of hydrophobic catheter substrate and hydrophilic hydrogel through the adhesive bottom layer, the coating has strong adhesion, is resistant to urine immersion and rubbing;Through polypeptide sustained-release carrier, antibacterial polypeptide is released for 30 days, and there is no risk of burst release;The targeted antibacterial polypeptide used is specific to urinary tract infection pathogenic bacteria, has no drug resistance induction risk, has excellent biocompatibility, can effectively prevent catheter-related urinary tract infection caused by short-term and long-term indwelling catheter, the preparation process is simple and controllable, is suitable for large-scale production, and can be widely applied to antibacterial modification of urinary intervention medical devices.

The application discloses a display module and a manufacturing method thereof. The display module comprises a display panel, a touch panel and a cover plate which are sequentially stacked, and further comprises a first flexible circuit board and a second flexible circuit board. In a flat state, the first flexible circuit board has a spacing or a contact surface with a side of the second cover plate part facing the first flexible circuit board. When the contact surface is formed, the area of the orthogonal projection of the contact surface on the second cover plate part accounts for 1 / 8-1 / 5 of the area of the second cover plate part. The display module improves the reliability of the flexible circuit board, reduces the peeling of the cover plate and the probability of bubble generation in the display area. The manufacturing method is simple in steps, avoids bubble generation in the display area during the preparation process and does not need a bubble removal step.

The invention relates to a micromechanical component for a sensor device, having a first seismic mass (30a), wherein the first seismic mass, which is displaceable from its first rest position in a first direction (44) over a first limit path along a first axis, mechanically contacts a first stop structure, and having a second seismic mass (30b), which is displaceable from its second rest position at least along a second axis, wherein the second axis is parallel to or lies on the first axis, wherein a second stop surface (50b) of the second seismic mass, which is displaceable from its second rest position in a second direction (46) which is oriented opposite to the first direction along the second axis, mechanically contacts a first stop surface (50a) of the first seismic mass which is attached to the first stop structure. The invention also relates to a method for producing a micromechanical component for a sensor device.

This invention relates to a bis(naphthalimide)-based blue dye, its preparation method, and an electrowetting display ink. The dye has the following structural formula: it comprises two naphthalimide units, each containing one aromatic amine group and two straight-chain or branched alkyl groups, bridged by a diamine. The preparation method uses dibromonaphthalimide as an intermediate, which undergoes nucleophilic substitution reactions with the diamine and aromatic amine, respectively, to obtain the dye. The preparation method of the bis(naphthalimide)-based blue dye provided by this invention is simple in procedure, has mild reaction conditions, and is suitable for large-scale preparation.

The present application relates to the technical field of mixed terpenoids, and is a kind of benzotetraquinabicyclic mixed terpenoid compound and its preparation method and application, wherein the compound is obtained by the following steps: crushing mushroom fruiting body into powder; then, soaking the mushroom fruiting body with ethyl acetate to obtain an extract, concentrating the extract to obtain an extract; then, using normal phase silica gel filler, eluting the extract with petroleum ether-dichloromethane to obtain an elution fraction; finally, separating and purifying the obtained elution fraction by reverse phase high performance liquid chromatography.The present application has significant anti-gastric cancer activity, and the preparation method is simple, environmentally friendly and low in cost.

The application provides a bethyla huidobrensis bisexual attractant, a preparation method and application thereof. The bethyla huidobrensis bisexual attractant comprises methyl eugenol and isoamyl acetate. The attractant significantly improves the attraction effect on male and female bethyla huidobrensis, reduces the use amount of methyl eugenol, has the advantages of low cost and simple preparation, and is suitable for industrialized production of the bethyla huidobrensis killing agent.

The purpose of the present invention is to provide a method for manufacturing a semiconductor device, which suppresses a reduction in yield during a rewiring step and the like, and improves the yield during manufacturing of the semiconductor device and the like. The purpose of the present invention is also to provide an adhesive sheet for manufacturing a semiconductor device, which is capable of suppressing a reduction in yield during a rewiring step or the like. Another purpose of the present invention is to provide a wound body around which the adhesive sheet for semiconductor device manufacturing is wound. The present invention is a method for manufacturing a semiconductor device having a first step, a second step, and a third step. A first step is a step for laminating, on a support substrate, an adhesive sheet having a metal layer and an adhesive layer containing a resin. And a second step for forming a semiconductor rewiring layer on the metal layer. And a third step for removing the support substrate and the adhesive layer.

The invention discloses NAS microcrystalline glass powder and a preparation method thereof, and relates to the technical field of microcrystalline glass. The preparation method comprises the following steps: providing sol, wherein the sol is prepared from the following components in parts by mass: 12 to 15 parts of aluminum silicate, 7 to 9 parts of NaOH, 60 to 70 parts of water, 1.0 to 5.8 parts of nano gas-phase SiO2 and 1 to 1.3 parts of TiO2; and drying the sol, heating the obtained dry gel to 750-850 DEG C at a heating rate of 3-5 DEG C / min, carrying out heat preservation for 0.5-1 h, cooling to room temperature, and carrying out crushing and ball milling on the obtained NAS glass ceramic block to obtain the NAS glass ceramic powder. The sol-gel combined one-time low-temperature sintering and recrystallization process is adopted, the energy consumption is low, the steps are simple, and the prepared NAS microcrystalline glass is uniform in component, high in density, crystallinity and mechanical strength and low in thermal expansion coefficient and dielectric loss.

A wide-temperature low-loss high-strength MnZn power ferrite, and a preparation method therefor and the use thereof. The wide-temperature low-loss high-strength MnZn power ferrite is comprised of a main component and an auxiliary component, wherein the mass of the auxiliary component is 0.165-0.61 wt% of the main component; the main component comprises iron oxide, manganese oxide and zinc oxide; and the auxiliary component comprises a first auxiliary component and a second auxiliary component, the first auxiliary component being cobalt oxide, and the second auxiliary component comprising at least three of calcium carbonate, niobium oxide, vanadium oxide and molybdenum oxide. By means of adding the auxiliary component, especially adding cobalt oxide with a specific mass, the cooperative adjustment of the specific ratio of Fe2+ to Co2+ is achieved, and power consumption is ensured to be effectively reduced without being influenced by temperature changes, such that the prepared wide-temperature low-loss high-strength MnZn power ferrite can have, at 25-120°C, the characteristics of low loss, a high magnetic flux density and an increase in strength by 10% or more.

The application discloses a manufacturing method of a plum-blossom liquid pump stator, which comprises the following steps: S1, metal body casting forming, S2, first injection molding monomer and second injection molding monomer installation, S3, upper mold installation, S4, engineering plastic layer one-time injection molding forming and demolding, and S5, engineering plastic layer secondary injection molding forming and demolding. The application can realize the secondary injection molding forming of the engineering plastic layer, improve the connection strength and stability between the engineering plastic layer and the metal body, prevent the engineering plastic layer from falling off in the injection molding process and affecting the processing quality and stability of the stator, effectively control the deformation amount of the engineering plastic layer, and improve the working stability of the plum-blossom liquid pump.

The present application relates to a kind of barium-doped carbon-supported iron nanoparticle materials and its preparation method and application in catalytic ammonia pyrolysis hydrogen production, the barium-doped carbon-supported iron nanoparticle material is obtained by mixing the iron-based carbon material that organic iron is uniformly dispersed in phenol formaldehyde resin after carbonization with barium salt solution, freeze-drying and calcination again, iron nanoparticles are uniformly distributed on the surface and inside of the barium-doped carbon-supported iron nanoparticle material, and barium element is uniformly dispersed on the surface of the barium-doped carbon-supported iron nanoparticle material.The barium-doped carbon-supported iron nanoparticle material provided by the present application has good catalytic ammonia pyrolysis hydrogen production performance, and the conversion efficiency of ammonia gas reaches more than 90% under the condition of 550 DEG C, space velocity 6000h ‑1 , and the cost is low, and it has good industrial application prospect.