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787 results about "Diarrhea" patented technology

Loose, watery stools that lasts for more than 2 weeks.

Nutritional composition, food containing same and application of nutritional composition

The invention relates to a nutritional composition. The nutritional composition comprises medium-chain and long-chain fatty acid triglyceride and nervonic acid in a mass ratio of (3: 1)-(1500: 1), and has a synergistic effect in the aspects of preventing or relieving diarrhea, inhibiting staphylococcus aureus in vivo or in vitro and / or preventing or treating inflammation. The invention also relates to a food product comprising said nutritional composition. The invention also relates to application of the nutritional composition in preparation of products with one or more purposes selected from 1) to 3): 1) preventing or relieving diarrhea; 2) inhibiting staphylococcus aureus in vivo or in vitro; and 3) preventing or treating inflammation.
Owner:INNER MONGOLIA MENGNIU DAIRY IND (GROUP) CO LTD +1

Streptococcus non-lactolyticus GX-7 and application of complex microbial inoculant thereof in sugarcane leaf silage

PendingCN120682983AAntibacterial agentsBacteriaBiotechnologyShigella sp
The invention relates to the technical field of microorganisms, in particular to application of streptococcus non-lactolyticus GX-7 and a complex microbial inoculant thereof in sugarcane leaf silage, the strain GX-7 is separated from healthy pig manure by a research group, and through detection, the strain has good cholate resistance and is suitable for surviving in intestinal tracts, and the strain GX-7 has good cholate resistance and is suitable for being used as a feed additive. The antibacterial effect on pseudomonas fluorescens, listeria monocytogenes, salmonella choleraesuis and shigella flexneri is achieved; the strain has a good fermentation capability on sugarcane leaves, and the sugarcane leaves are inoculated with a complex microbial inoculant prepared from streptococcus non-lactolyticus GX-7 and streptococcus non-lactolyticus GX-2, so that a synergistic fermentation effect can be achieved; after the silage prepared from the complex microbial inoculant is fed to female buffalo in the gestation period, it is found that the silage can effectively increase the content of milk protein, milk total solids and milk non-fat solids in colostrum of the female buffalo and relieve diarrhea of the female buffalo, and the silage is safe and good.
Owner:GUANGXI ZHUANG AUTONOMOUS REGION ACAD OF AGRI SCI

Postbiotic preparation for pets as well as preparation method and application of postbiotic preparation

The invention belongs to the technical field of microorganisms, and particularly relates to a postbiotic preparation for pets as well as a preparation method and application of the postbiotic preparation. The metabolite preparation provided by the invention comprises a lactobacillus plantarum Ps-8 inactivated thallus and a metabolite thereof, a lactobacillus casei C-9 inactivated thallus and a metabolite thereof, a bifidobacterium animalis subsp. Lactis BB-16 inactivated thallus and a metabolite thereof, and a lactobacillus acidophilus LA-14 inactivated thallus and a metabolite thereof. The pet food can be applied to various food types of different varieties of cat and dog pets, and has the effects of improving the intestinal barrier function of the pets, enhancing the immunity, reducing the incidence rate of diarrhea, reducing the food change stress, promoting the digestion of nutrient substances, optimizing the state of spirit and fur, reducing the odor of excrement, fading the odor of the oral cavity, improving the health level of the oral cavity and teeth and the like.
Owner:INNER MONGOLIA KETUO MICRO-ECOLOGICAL TECH DEV CO LTD

Fatty acid composition and application thereof in preparation of products for improving intestinal health

The invention relates to the technical field of feed products, in particular to a fatty acid composition and application thereof in preparation of products for improving intestinal health. The fatty acid composition comprises arachidonic acid, docosahexaenoic acid, eicosapentaenoic acid, butyric acid and lauric acid, or a precursor substance capable of releasing the fatty acid in the digestive tract, and the mass of the fatty acid composition is calculated according to the mass of the arachidonic acid, the mass of the docosahexaenoic acid, the mass of the eicosapentaenoic acid, the mass of the butyric acid and the mass of the lauric acid. The additive is prepared from the following components in parts by weight: 7-10 parts of arachidonic acid, 3-7 parts of docosahexaenoic acid, 3-7 parts of eicosapentaenoic acid, 2-5 parts of butyric acid and 1-3 parts of lauric acid. The composition can effectively relieve inflammation and diarrhea, regulate intestinal flora and improve intestinal health, and drug resistance is not prone to being generated.
Owner:CABIO BIOTECH (WUHAN) CO LTD +1

Nutritional composition and application thereof

The invention provides a nutritional composition and application of the nutritional composition. The nutritional composition comprises medium-chain and long-chain fatty acid triglyceride (MLCT) and milk fat globule membrane (MFGM) in a mass ratio of 2: 1 to 80: 1, and the combination of the two has the effects of synergistically improving diarrhea, inhibiting staphylococcus aureus in vivo or in vitro and / or regulating intestinal flora.
Owner:INNER MONGOLIA MENGNIU DAIRY IND (GROUP) CO LTD +1

Animal combined lactobacillus D27 as well as screening method and application thereof

The invention discloses animal combined lactobacillus D27 as well as a screening method and application thereof, and relates to the technical field of microorganisms, and the key points of the technical scheme are as follows: the animal combined lactobacillus D27 is preserved in China General Microbiological Culture Collection Center (CGMCC) on May 9, 2024, and the preservation number is CGMCC No.30561. The animal combined lactobacillus D27 has the advantages that the animal combined lactobacillus D27 can be used for screening the animal combined lactobacillus D27; the animal combined lactobacillus D27 provided by the invention is a strain with excellent performance screened from the digestive tract of the calf, has the characteristics of stronger acid resistance, cholate resistance, strong adhesiveness, high lactic acid production and the like, and provides an excellent strain resource for the development of probiotics for preventing and treating calf diarrhea.
Owner:FEED RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES

Method for predicting and judging diarrhea risk grade of suckling piglet

The invention discloses a method for predicting and judging the diarrhea risk grade of suckling piglets, and belongs to the technical field of piglet epidemic disease prevention and control. Aiming at the problems that traditional piglet diarrhea prediction depends on manual observation, multi-dimensional data relevance is insufficient, early warning lags and the like, a multi-parameter monitoring device is arranged in a piglet breeding environment to collect environment data in real time, and an excretion behavior detection module is used for triggering an excrement image collection device to obtain a high-quality image; and inputting multi-source data into a random forest model for risk level prediction by combining regular weight measurement and blood detection in a specific time period after environment adjustment. The system dynamically adjusts pig environment parameters according to a prediction result, after spraying, heating compensation is started to maintain humidity and control ammonia concentration, and closed-loop feedback regulation is formed. According to the method, through multi-modal data fusion and model iterative optimization, early-stage accurate early warning of diarrhea risks is realized, the method is suitable for intelligent management of a large-scale pig farm, the diarrhea occurrence rate can be effectively reduced, and the breeding benefits are improved.
Owner:GUANGXI NONGKEN YONGXIN ANIMAL HUSBANDRY GRP XINXING CO LTD

Streptococcus non-lactolyticus GX-2 and application of complex microbial inoculant thereof in peanut vine silage

PendingCN120505254AAntibacterial agentsBacteriaBiotechnologyStreptococcus alactolyticus
The invention relates to the technical field of microorganisms, in particular to application of streptococcus non-lactolyticus GX-2 and a complex microbial inoculant thereof in peanut vine silage, and the strain GX-2 is suitable for surviving in the stomach and has an antibacterial effect on staphylococcus aureus, escherichia coli, pseudomonas fluorescens and listeria monocytogenes; the streptococcus non-lactolyticus GX-7 and the streptococcus non-lactolyticus GX-2 are prepared into a complex microbial inoculant, and then the complex microbial inoculant is inoculated into the peanut vines, so that the synergistic fermentation effect can be achieved at the mass ratio of 1: (1-3); after the gestational buffalo is fed with the silage prepared from the complex microbial inoculant, the silage is found to be capable of effectively increasing the contents of total milk solids and non-fat milk solids in the colostrum of the buffalo and relieving the diarrhea of the buffalo, and is safe and good.
Owner:GUANGXI ZHUANG AUTONOMOUS REGION ACAD OF AGRI SCI

Milk powder composition containing breast milk oligosaccharide and easy to digest and absorb and application of milk powder composition

The invention provides a milk powder composition containing breast milk oligosaccharide and easy to digest and absorb. The milk powder composition comprises the breast milk oligosaccharide, OPN, galactooligosaccharide, lactoferrin, alpha-whey protein, multivitamins, lactose, vegetable oil and compound minerals, wherein the weight ratio of the lactoferrin to the OPN to the breast milk oligosaccharide to the galactooligosaccharide is 1: (2-4): (2-50): (4-100). The composition can effectively recover and improve the intestinal barrier function caused by inflammatory factors, can be well absorbed by infants with poor digestion and absorption functions, reduces diarrhea and promotes skeletal development.
Owner:BIOSTIME (CHANGSHA) NUTRITION FOOD CO LTD

Pig excretion and diarrhea behavior intelligent identification and early warning method and system

The invention discloses a pig excretion and diarrhea behavior intelligent identification early warning method and system, and the method comprises the steps: collecting a video stream of pig activities in a pig house through a thermal infrared camera which is installed in a top view manner, and carrying out the Mosaic data enhancement preprocessing of a video image; reasoning the preprocessed video single frame by using a YOLOv10 target detection model, and generating a space attention mask for the excrement area; based on the space attention mask, background noise is suppressed, and spatio-temporal features related to excretion behaviors are enhanced; the enhanced spatial-temporal features are input into an ActionMama network based on a state space model for time sequence action positioning, and an identification result containing urination and defecation behavior types and action starting and ending time is output; and according to the excretion frequency, the single excretion duration and the excretion position space information in the identification result, generating a pig diarrhea behavior early warning signal. According to the embodiment of the invention, the problems of high omission ratio and early warning lag can be effectively solved, and the intelligent level and timeliness of pig health management are improved.
Owner:CHONGQING ACAD OF ANIMAL SCI +1

Model system for predicting enteral nutrition diarrhea risk of critical patient

The invention relates to the technical field of critical nutrition medical treatment, and discloses a critical patient enteral nutrition diarrhea risk prediction model system. A nutrition parameter acquisition module of the system is used for acquiring enteral nutrition formula parameters, including nutrient solution osmotic pressure, infusion speed and nutrient solution temperature, of a critical patient; the physiological index analysis module is used for collecting intestinal flora abundance data, serum albumin level and gastrointestinal peristalsis frequency of the critical patient; the risk feature extraction module is used for calculating an intestinal tolerance feature value according to the enteral nutrition formula parameters and the intestinal flora abundance data; and the prediction model construction module is used for constructing a diarrhea risk prediction model based on the intestinal tolerance characteristic value and the serum albumin level. According to the system, comprehensive acquisition and analysis of enteral nutrition related data of critical patients can be realized, objectivity and accuracy of diarrhea risk prediction are improved, and support is provided for clinical enteral nutrition scheme adjustment and diarrhea prevention.
Owner:FUJIAN PROVINCIAL HOSPITAL

A prebiotic feed additive for promoting intestinal health of pigs and preparation method thereof

The present invention relates to a prebiotic feed additive for promoting intestinal health of pigs, belonging to the technical field of feed, the prebiotic feed additive of the present invention comprises prebiotic components and biological adjuvants, the prebiotic components comprise oligofructose, oligoisomaltose, inulin and resistant dextrin, the biological adjuvant is a product obtained by co-enzymatic hydrolysis of dandelion and houttuynia cordata by hemicellulase and pectinase, then fermented by Lactobacillus acidophilus and Propionibacterium freudenreichii in sequence, and finally enzymatic hydrolyzed by bromelain and trypsin step by step. The components in the additive are used in combination to have a good effect of promoting intestinal health of pigs, can balance and improve the intestinal microenvironment, improve feed nutrient utilization, enhance immunity, reduce diarrheal diseases, and promote growth and weight gain.
Owner:TIANJIN MODERN TIANJIAO AGRI TECH CO LTD

Health-care product with weight-losing effect as well as preparation method and application of health-care product

The invention discloses a health-care product with a weight-losing effect as well as a preparation method and application of the health-care product. The health-care product is prepared from the following raw materials in parts by weight: 1-5 parts of an aloe extract, 5-10 parts of an acanthopanax sessiliflorus leaf extract, 20-30 parts of pigeon pea natto powder and 40-60 parts of auxiliary materials. Research finds that the aloe extract, the acanthopanax sessiliflorus leaf extract and the pigeon pea natto powder are combined to play an obvious weight-losing role in the aspects of inhibiting lipase activity, regulating lipid metabolism, increasing energy consumption, controlling appetite and the like; by using the pigeon pea natto powder, the diarrhea phenomenon caused by the aloe extract and the acanthopanax sessiliflorus leaf extract can be obviously reduced. The three components and a proper amount of auxiliary materials are compounded to prepare the health-care product, and the health-care product can be used for reducing blood sugar, reducing lipid and losing weight and has the advantages of being natural, green, safe in property, remarkable in effect and small in side effect.
Owner:GUANGZHOU SEAGREEN BIOTECHNOLOGY CO LTD

Betulinic acid type saponin derivative as well as preparation method and application thereof

The invention relates to betulinic acid type saponin derivatives as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The structural general formula of the betulinic acid type saponin derivative is # imgabs0, R1 is selected from hydroxyl or-O-G, and G is monosaccharide; r2 is selected from dopamine, 5-aminovaleric acid, 4-aminobutyric acid or 3-aminopropionic acid and the like and salts thereof. The betulinic acid type saponin derivative does not show obvious cytotoxicity to THP-1 macrophages, and can obviously reduce the release of IL-6 and IL-1beta in the THP-1 macrophages induced by LPS (lipopolysaccharide). Compared with betulinic acid and positive control medicine mesalazine, the pharmaceutical composition has better anti-inflammatory activity, has the treatment effect of improving diarrhea and hemafecia of mice with colitis remarkably superior to those of betulinic acid and positive control medicine mesalazine, has the treatment effect of dermatitis superior to that of positive control medicine dexamethasone, and does not have obvious toxic or side effects such as weight loss and immunosuppression. Therefore, the betulinic acid type saponin derivative has good in-vivo and in-vitro safety and druggability.
Owner:SUZHOU UNIV

Health condition estimation system for toilet users

To provide a health condition estimation system for toilet users, which appropriately estimates health conditions of people.SOLUTION: In a health condition estimation system for toilet users disclosed herein, a condition estimation device comprises log information acquisition means (an acquisition unit) for acquiring a toilet log indicative of a usage status of a toilet apparatus, and condition estimation means (an estimation unit) for estimating a health condition of a toilet user based on the toilet log acquired by the log information acquisition means. The condition estimation means estimates an intestinal condition, including constipation or diarrhea, on the basis of a defecation record included in the toilet log.SELECTED DRAWING: Figure 4
Owner:TOTO LTD

Ackermann muciniphile, combined microbial agent thereof and application of ackermann muciniphile in inflammatory enteritis

The invention relates to the technical field of microorganisms, and discloses Ackermann muciniphila, a combined microbial agent thereof and application of the Ackermann muciniphila in inflammatory enteritis. The invention provides Akkermansia muciniphila AIML-559, and the preservation number of the Akkermansia muciniphila AIML-559 is CGMCC (China General Microbiological Culture Collection Center) No. 34246. The invention relates to a combined microbial agent, which is characterized by comprising Ackermann muciniphila AIML-559 and Bifidobacterium adolescentis AIML-528 (the preservation number is CGMCC (China General Microbiological Culture Collection Center) No.34300). The combined microbial agent is prepared from the following raw materials: Ackermann muciniphila AIML-559 and Bifidobacterium adolescentis AIML-528 The ackermann mucophil combined microbial inoculum is suitable for treatment intervention of inflammatory bowel disease (IBD), and can relieve weight loss, hemolysis, anemia, diarrhea, intestinal bleeding and other symptoms of IBD mice.
Owner:BEIJING YUANYANG XINGCHEN BIOTECHNOLOGY CO LTD

Oral probiotic-mediated drug delivery system as well as preparation method and application thereof

The invention relates to an oral probiotic-mediated drug delivery system as well as a preparation method and application thereof. The preparation method comprises the following steps: preparing polydopamine nano coating bacteria from probiotics and dopamine; a process of preparing drug-loaded polydopamine nanoparticles from dopamine and a functional drug; and a process of preparing a drug delivery system from the polydopamine nano-coated bacteria and the drug-loaded polydopamine nanoparticles, the drug delivery system prepared by the method is applied to preparation of drugs for preventing or treating tumors, colitis, diarrhea, constipation, diabetes mellitus and obesity. The preparation method disclosed by the invention has the advantages of simple preparation, mildness and stable performance, the prepared drug delivery system adopts a polydopamine single bacterium coating method to encapsulate the probiotics, and the drug-loaded nanoparticles are loaded on the surface of the probiotics, so that the effects of efficient drug delivery and micro-ecological regulation functions are achieved, and a better treatment effect is achieved.
Owner:ZHEJIANG UNIV OF TECH

Feed additive for synergistically improving oxidative stress resistance of broiler chickens based on oleuropein-luteoloside-maslinic acid ternary combination and application of feed additive

The invention discloses a feed additive for synergistically improving oxidative stress resistance of broiler chickens based on oleuropein-luteoloside-maslinic acid ternary combination and application of the feed additive, the feed additive is the olea europaea leaf extract, the total polyphenol content of the feed additive is about 52%, the total flavone content is 7%, and the total flavone content is 5%. The feed is mainly composed of oleuropein, luteolin-7-beta-glucoside and maslinic acid, the oleuropein, the luteolin-7-beta-glucoside and the maslinic acid are sequentially added in a molar ratio of 6: 1: 1 to generate a synergistic anti-oxidative stress effect, and when the feed is applied to breeding on the basis of corn-soybean daily ration of broilers, the daily gain of the broilers can be obviously increased, the feed conversion ratio is reduced, and the feed conversion rate is increased. The intestinal micro-ecological health, the anti-oxidative stress effect and the organism immunity are improved, and the infection rate and the death rate of intestinal diseases such as diarrhea of broilers are reduced. The product has the advantages of being simple and convenient to prepare and use, free of toxic and side effects, beneficial to broiler chicken growth and human health, free of the problems of drug resistance, drug residues and the like, and capable of promoting chicken meat quality improvement and the like.
Owner:INST OF CHEM IND OF FOREST PROD CHINESE ACAD OF FORESTRY

RNA vaccine for porcine epidemic diarrhea and preparation method therefor

Provided are an RNA vaccine for porcine epidemic diarrhea and a preparation method therefor. The RNA vaccine is obtained by means of gene synthesis, in-vitro transcription, and lipid nanoparticle encapsulation, which can rapidly respond to the currently prevalent new PEDV strains, reduces the research and production cycle of new vaccine development, and provides an effective technical approach for the prevention and control of newly mutated highly virulent strains. The prepared RNA vaccine for porcine epidemic diarrhea has high production efficiency, can induce relatively high levels of porcine epidemic diarrhea virus neutralizing antibodies and binding antibodies in vivo, effectively reducing the occurrence of diarrhea in piglets, and thus holds great promotional value for the prevention and control of porcine epidemic diarrhea.
Owner:SUZHOU HEALIRNA BIOTECHNOLOGY CO LTD +1

Animal cub culture device for animal husbandry and veterinary medicine

The invention relates to the technical field of animal cub culture, in particular to an animal cub culture device for animal husbandry veterinarians, which comprises a culture box, a transparent door plate slidably connected to the culture box, a hollow plate inserted into the culture box, an excrement groove hung at the rear end of the culture box, a diversion groove formed in the lower end in the culture box, and a discharge groove formed in the rear wall of the culture box. The driving assembly is located in the incubator and comprises two movable blocks, the upper ends of the movable blocks are fixedly connected with push blocks, a guide rail is fixedly arranged on the top face of the upper end of the incubator, the upper ends of the two push blocks are slidably connected with the guide rail, and the outer walls of the two sides of each movable block are communicated with a plurality of nozzles. The flushed and disinfected area is dried through hot air, the cleaning effect of excrement of the cubs is improved, excrement residues are reduced, bacterium breeding is reduced, a healthy environment is provided for cub culture, and the morbidity of diarrhea, skin diseases and the like of the cubs is reduced.
Owner:SICHUAN PRORINA BIOTECHNOLOGY CO LTD

Method for treating piglet damp-heat diarrhea through multi-omics combined analysis of scutellaria baicalensis

The invention discloses a method for treating piglet damp-heat diarrhea through multi-omics combined analysis. According to the method, faeces metabonomics, intestinal transcriptomics and intestinal flora 16s analysis are adopted, transcriptome data, metabolome data and intestinal flora data are screened according to a prime difference standard, then transcriptomics of a model group and a control group, faeces metabonomics and intestinal flora are subjected to conjoint analysis, an intersection is taken, and the faeces metabonomics of the model group and the control group, the faeces metabonomics of the model group and the control group and the intestinal flora of the model group and the control group are subjected carrying out conjoint analysis on transcriptomics of the Model group and HQ-M, faeces metabonomics and intestinal flora, and then taking an intersection; the method comprises the following steps of: selecting a plurality of metabolites and florae from a plurality of intestinal florae, respectively obtaining intersections, screening related genes, searching gene FPKM expression quantity in transcriptomics, and screening corresponding metabolites and florae in metabonomics and intestinal florae to obtain a gene-flora-metabolite related network diagram. Multi-omics combined analysis shows that the piglet diarrhea due to damp-heat is mainly manifested by inflammation and glucose and lipid metabolism disorder.
Owner:GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE

Quality control method for mixing process of intestine-strengthening and diarrhea-stopping pills based on NIRS spectrum combined with MSPC technology

The invention belongs to the field of quality control of modern traditional Chinese medicines, and discloses a quality control method for a mixing process of intestine-strengthening and diarrhea-stopping pills based on combination of NIRS spectrum and MSPC technology. The method comprises the following steps: pre-treating medicinal materials according to a prescription proportion; an NIRS spectrometer is adopted to collect data; performing variable expansion and dimensionality reduction on the three-dimensional spectrum data, establishing an MSPC model in batches based on a training set, and setting a control limit according to a standard deviation + / -3 times of a mean value of a principal component score (PC1), Hotelling Tand DModX statistical magnitude; and a new batch of spectrum data is input in real time, and feeding abnormity and process abnormity are jointly monitored through three types of statistics. A PLS quantitative model is synchronously established, and dynamic content prediction of the six chemical components such as neochlorogenic acid is achieved. According to the method, real-time early warning of abnormity in the mixing process and dynamic analysis of chemical components are achieved, and the uniformity and stability of the quality of the intestine-strengthening and diarrhea-stopping pills are remarkably improved.
Owner:SHAANXI UNIV OF CHINESE MEDICINE

Bacillus subtilis and application thereof

The invention relates to bacillus subtilis, the bacillus subtilis is named as bacillus subtilis BS02, the bacillus subtilis is preserved in the China Center for Type Culture Collection, the preservation date is April 11, 2025, and the preservation number is CCTCC NO: M 2025753. The bacillus subtilis can be used for preparing a bacillus subtilis strain. According to the technical scheme, the bacillus subtilis BS02 is provided and can replace antibiotics for livestock after being processed, the number of viable bacteria of intestinal escherichia coli is reduced, the number of viable bacteria of beneficial bacteria is increased, then the intestinal health effect can be improved, and the incidence rate and the fatality rate of diarrhea can be reduced; meanwhile, the bacillus subtilis BS02 can also improve the average daily gain of the piglets to a certain extent and reduce the feed conversion ratio, and has objective application value in the field of feed additives.
Owner:WUHAN HUAYANG TIANLE BIOTECHNOLOGY CO LTD

Multi-layer multi-release metagen composition and application thereof

The invention discloses a multi-layer multi-release metagen composition and application thereof in quickly promoting defecation, lubricating intestinal tracts, relieving intestinal problems such as flatulence, stomachache, diarrhea, constipation, irritable bowel syndrome and inflammatory bowel disease, maintaining intestinal flora balance, repairing intestinal tracts, repairing intestinal mucosa health, relieving dyspepsia and improving gastrointestinal functions.
Owner:NANJING AURORA BOREALIS BIOTECHNOLOGY CO LTD

Application of monomethylsulfoline in preparation of medicine for treating ulcerative colitis

The invention relates to the technical field of medicines, and particularly discloses application of monomethylsulfoline in preparation of a medicine for treating ulcerative colitis. Experimental research finds that Monomethylsulochrin can obviously improve the conditions of weight loss, diarrhea, hemafecia, shortened colon length and the like of a mouse with UC (ulcerative colitis) induced by DSS, relieve inflammatory characterization of the UC mouse, effectively improve pathological damage of colon tissue of the UC mouse, effectively inhibit expression of inflammatory factors of the UC mouse and relieve inflammatory response of the UC mouse. Researches show that the monomethylsulfoline has an obvious and exact effect on treating ulcerative colitis, and can be used for preparing the medicine for treating ulcerative colitis. The invention provides a new medicine source for preventing and treating ulcerative colitis, and widens the application field of methylsulfoline.
Owner:GUANGXI MEDICAL UNIVERSITY

Probiotic and use thereof

Disclosed in the present invention is a probiotic. The probiotic comprises Parabacteroides distasonis with the microbial deposit number of CCTCC NO: M20222033, Limosilactobacillus fermentum with the microbial deposit number of CCTCC NO: M2023352, Lactobacillus salivarius with the microbial deposit number of CCTCC NO: M2023348, Enterococcus avium with the microbial deposit number of CCTCC NO: M2023350, and Bifidobacterium bifidum with the microbial deposit number of CCTCC NO: M2023349. The probiotic has good safety, has antioxidant activity, can inhibit pathogenic bacteria, can alleviate colon injury, can inhibit inflammation, and can alleviate diarrhea caused by chemotherapeutic drugs.
Owner:SICHUAN ANAEROBIC BIOTECHNOLOGY CO LTD

Excrement character recognition and drug delivery closed-loop control method and system

The invention discloses an excrement character recognition and drug delivery closed-loop control method and system, and the system comprises an excrement collection and preprocessing module which is used for carrying out the automatic collection, preliminary physical and chemical character detection and sample preprocessing of the excrement of a patient; the multi-modal data analysis module is used for carrying out deep fusion analysis on the original multi-modal data output by the excrement collection and preprocessing module and carrying out diarrhea type diagnosis and severity evaluation; the drug delivery closed-loop control module is used for accurately and dynamically infusing drugs according to the diagnosis result of the multi-modal data analysis module; and the man-machine interaction and early warning module is used for monitoring and intervening the state of the system by medical staff and receiving important alarms. According to the invention, objective and continuous evaluation of excrement properties is realized, the drug dosage and scheme can be dynamically adjusted according to the properties, and the accuracy, individualization level and safety of diarrhea treatment of critical patients are significantly improved.
Owner:THE FIRST AFFILIATED HOSPITAL OF ANHUI MEDICAL UNIV

Preparation method of aronia melanocarpa relaxing juice

The invention relates to a preparation method of aronia melanocarpa relaxing juice, and belongs to the field of food processing. The preparation method comprises the following steps: adding an edible gelatin aqueous solution with a freezing force value of 120-250Bloom g into aronia melanocarpa juice to obtain a mixed solution, adjusting the pH value of the mixed solution to 2-5, carrying out a water bath reaction, rapidly cooling, standing, filtering, sterilizing and canning to obtain the aronia melanocarpa softening juice. According to the method, specific precipitation of condensed tannin is realized by accurately regulating and controlling molecular conformation and reaction pH of gelatin, so that the content of condensed tannin in the aronia melanocarpa juice is reduced, adverse symptoms such as diarrhea and gas displacement increase caused by the condensed tannin are effectively relieved, meanwhile, a bioactive substance anthocyanin in the aronia melanocarpa juice is not destroyed by the method, and the method is suitable for large-scale production of the aronia melanocarpa juice. The raw material composition is simple, and the process is convenient and easy to implement.
Owner:SHENYANG AGRI UNIV

Probiotic preparation for improving intestinal health of pets and application thereof

The invention relates to a probiotic preparation for improving intestinal health of pets and application of the probiotic preparation. The bacterial strains in the probiotic preparation consist of a bacillus coagulans BC66 bacterial strain with the preservation number of CGMCC (China General Microbiological Culture Collection Center) 21879, a pediococcus acidilactici PA153 bacterial strain with the preservation number of CCTCC NO: M 2023230, a lactobacillus plantarum LP194 bacterial strain with the preservation number of CGMCC 21766, a bifidobacterium animalis BA20 bacterial strain with the preservation number of CGMCC No. 21830 and a lactobacillus reuteri LR108 bacterial strain with the preservation number of GDMCC No: 63095. According to the probiotic preparation, five specific probiotics are compounded, the five strains are matched and promoted with one another, and synergistic interaction is achieved on the effect of improving the intestinal health of pets, specifically, the digestive ability of the pets on nutrients is improved; the immunity of pets is improved and the diarrhea rate is reduced; the content of beneficial bacteria in intestinal tracts of pets is increased.
Owner:SUZHOU WEIKANG AGRICULTURAL BIOTECHNOLOGY CO LTD +2

Phytobacterium plantarum for improving intestinal immunity and fermented product

The invention discloses a plant lactobacillus PC037 capable of improving intestinal immunity and a fermented product. The plant lactobacillus PC037 is preserved in the China General Microbiological Culture Collection Center on December 13, 2021, and the preservation number is CGMCC (China General Microbiological Culture Collection Center) No. 24096. The plant lactobacillus PC037 can improve the repair speed of the intestinal mucosa and promote the enhancement of the immunity of the intestinal tract. The plant lactobacillus fermented product capable of improving the immunity of the intestinal tract, provided by the invention, can be used for adjusting the exhaust frequency, promoting the enhancement of the immunity of the intestinal tract and reducing the occurrence frequency of diarrhea caused by pathogenic bacteria infection of travelers in a travel process.
Owner:GUANGZHOU TONGKANG BIOTECHNOLOGY CO LTD +1