371 results about "Diarrhea" patented technology

The invention discloses a pig excretion and diarrhea behavior intelligent identification early warning method and system, and the method comprises the steps: collecting a video stream of pig activities in a pig house through a thermal infrared camera which is installed in a top view manner, and carrying out the Mosaic data enhancement preprocessing of a video image; reasoning the preprocessed video single frame by using a YOLOv10 target detection model, and generating a space attention mask for the excrement area; based on the space attention mask, background noise is suppressed, and spatio-temporal features related to excretion behaviors are enhanced; the enhanced spatial-temporal features are input into an ActionMama network based on a state space model for time sequence action positioning, and an identification result containing urination and defecation behavior types and action starting and ending time is output; and according to the excretion frequency, the single excretion duration and the excretion position space information in the identification result, generating a pig diarrhea behavior early warning signal. According to the embodiment of the invention, the problems of high omission ratio and early warning lag can be effectively solved, and the intelligent level and timeliness of pig health management are improved.

The invention relates to the technical field of animal cub culture, in particular to an animal cub culture device for animal husbandry veterinarians, which comprises a culture box, a transparent door plate slidably connected to the culture box, a hollow plate inserted into the culture box, an excrement groove hung at the rear end of the culture box, a diversion groove formed in the lower end in the culture box, and a discharge groove formed in the rear wall of the culture box. The driving assembly is located in the incubator and comprises two movable blocks, the upper ends of the movable blocks are fixedly connected with push blocks, a guide rail is fixedly arranged on the top face of the upper end of the incubator, the upper ends of the two push blocks are slidably connected with the guide rail, and the outer walls of the two sides of each movable block are communicated with a plurality of nozzles. The flushed and disinfected area is dried through hot air, the cleaning effect of excrement of the cubs is improved, excrement residues are reduced, bacterium breeding is reduced, a healthy environment is provided for cub culture, and the morbidity of diarrhea, skin diseases and the like of the cubs is reduced.

The invention discloses an excrement character recognition and drug delivery closed-loop control method and system, and the system comprises an excrement collection and preprocessing module which is used for carrying out the automatic collection, preliminary physical and chemical character detection and sample preprocessing of the excrement of a patient; the multi-modal data analysis module is used for carrying out deep fusion analysis on the original multi-modal data output by the excrement collection and preprocessing module and carrying out diarrhea type diagnosis and severity evaluation; the drug delivery closed-loop control module is used for accurately and dynamically infusing drugs according to the diagnosis result of the multi-modal data analysis module; and the man-machine interaction and early warning module is used for monitoring and intervening the state of the system by medical staff and receiving important alarms. According to the invention, objective and continuous evaluation of excrement properties is realized, the drug dosage and scheme can be dynamically adjusted according to the properties, and the accuracy, individualization level and safety of diarrhea treatment of critical patients are significantly improved.

The invention belongs to the field of pet food processing, and relates to a functional pet food for regulating intestinal health and a preparation method thereof. The functional pet food can increase MTL content in dog serum in a physiological range, reduce DAO activity and D-lactic acid and LPS content in dog serum, improve intestinal mucosa barrier function, and significantly improve dog intestinal health. The functional pet food can shorten gastrointestinal transmission time and effectively improve constipation. The functional pet food disclosed by the invention has a good effect in the aspects of treating diarrhea and constipation, and has a two-way regulation effect in regulating intestinal flora imbalance. The components of the raw materials have a synergistic effect, the nutrition is balanced, the preparation method is simple, the palatability is optimally designed, and the metabolic characteristic is free of burden, so that pets can safely take the feed for a long time, a convenient and efficient preventive health management scheme is provided for family pet raising, and the feed has a relatively good commercial application prospect.

The invention relates to the technical field of microorganisms, and particularly discloses a lactobacillus paracasei KQNIU, a microbial preparation and application of the lactobacillus paracasei KQNIU. The Lactobacillus paracasei KQNIU is preserved in the China General Microbiological Culture Collection Center on August 25, 2025, the preservation number is CGMCC No.35739, and the Lactobacillus paracasei KQNIU is classified and named as Lactobacillus paracasei, and the Lactobacillus paracasei KQNIU is named as Lactobacillus paracasei KQNIU. The Lactobacillus paracasei KQNIU is named as Lactobacillus paracasei KQNIU. The lactobacillus paracasei KQNIU provided by the invention has good gastrointestinal tract tolerance, has an inhibition effect on pathogenic bacteria such as escherichia coli, salmonella and the like, can be prepared into a microbial preparation or a feed additive for preventing and treating calf diarrhea, replaces antibiotics and realizes green and healthy breeding.

The invention discloses a lactobacillus mucus fermentation strain. The microbial preservation number of the lactobacillus mucus fermentation strain is CCTCC (China Center for Type Culture Collection) NO: M 20252262. The strain can inhibit enterotoxigenic escherichia coli, and can treat or slow down diarrhea, intestinal oxidative damage, intestinal inflammation damage, intestinal morphological damage, intestinal barrier function damage and intestinal flora disorder caused by the enterotoxigenic escherichia coli. The strain is a probiotic with a clinical application prospect.

The invention discloses saccharomyces boulardii, a culture and a preparation method and application of the saccharomyces boulardii. The preservation number of the strain is CCTCC (China Center for Type Culture Collection) NO: M 20252633. The preparation method comprises the following steps: preparing saccharified liquid by taking white spirit vinasse or brewer's grains as a main raw material and adopting a high-temperature alkali treatment and composite enzymolysis process, inoculating strains for liquid-state high-density fermentation, carrying out solid-liquid separation on fermentation liquor, taking a liquid phase, and carrying out spray drying. According to the method, high-value utilization of the waste vinasse is realized, and the production cost is remarkably reduced. The obtained culture is rich in viable bacteria and active small peptides, and has the characteristics of strong tolerance, wide antibacterial spectrum and the like. As a feed additive, the feed additive can effectively reduce the diarrhea rate of piglets, inhibit clostridium perfringens and prawn vibrios of broilers, and improve the oxidation resistance and production performance of animals.

The invention relates to the technical field of medical biology, in particular to a chronic pancreatitis complication risk grading system based on exosome transcriptome data, and aims to solve the problems that existing chronic pancreatitis (CP) typing lacks molecular basis, complication risk prediction is weak and clinical transformation is poor. According to the system, plasma exosomes are extracted and sequenced, a functional characteristic gene set is constructed in combination with pancreas single cell data, CP is divided into three risk increasing subtypes by using a COCA algorithm, and finally 12 core miRNAs are screened to construct a BPNN diagnosis model. The invention proves that the plasma exosome can be used for staging classification of chronic pancreatitis for the first time, miRNA non-invasive accurate layering illness conditions can be detected through qPCR, the risk of fatty diarrhea and 3c type diabetes mellitus can be predicted, and the non-invasiveness, convenience, classification accuracy and result repeatability of the plasma exosome have clinical application and transformation advantages.

The invention discloses application of bifidobacterium longum subsp. Infantis CCFM1269 in preparation of a product for relieving lactoglobulin allergy, and belongs to the technical field of microorganisms. The bifidobacterium longum subsp. Infantis CCFM1269 provided by the invention can relieve food allergy, and the food allergy can be relieved specifically as follows: (1) allergy symptom score and diarrhea occurrence rate can be relieved, and anus temperature and immune organ index can be recovered; (2) the immune response is regulated, the levels of histamine, total IgE, IgG1, beta-lactoglobulin specific IgE and proinflammatory factors IL-4 and IL-17A in serum are reduced, the levels of IFN-gamma and IL-10 are improved, and the immune balance is recovered; (3) inflammation of lung and jejunum tissues is relieved; (4) improving the oxidative stress state; (5) the intestinal barrier function is enhanced; and (6) recovering the diversity of intestinal flora, and adjusting the relative abundance of key bacteria genus such as Alloprevotella and the like.

The invention provides a functional feed additive for relieving oxidative damage to intestinal tracts of piglets as well as a preparation method and application of the functional feed additive. The functional feed additive is prepared from the following components in parts by weight: 30 to 50 parts of plant extract, 0.5 to 2 parts of operculate cleistocalyx flower polyphenol-mesoporous silicon dioxide nanoparticles, 0.05 to 1 part of vitexin and 1 to 3 parts of sugarcane polyphenol. The product provided by the invention can relieve intestinal structure damage caused by oxidative stress of piglets and protect normal structures and functions of intestinal tracts; inflammatory factors are reduced, inflammatory response is improved, and intestinal health is maintained; the piglet diarrhea is reduced, and the production performance of piglets is improved.

The invention discloses pediococcus acidilactici and application thereof in preparation of a medicine for preventing or treating diarrhea of yak calves, and belongs to the technical field of microorganisms. The pediococcus acidilactici is preserved in the China Center for Type Culture Collection, the preservation number is CCTCC NO: M20252012, and the preservation date is September 12, 2025. The strain has remarkable bacteriostatic activity on yak-derived multi-drug-resistant escherichia coli (the accession number of NCBI is PP859186). After the probiotic preparation is orally taken, the yak calf diarrhea induced by escherichia coli can be effectively relieved, the diarrhea rate and the inflammatory factor level are remarkably reduced, the oxidation resistance is improved, the flora structures of intestinal bacteria and fungi are adjusted, and the micro-ecological balance is restored. The invention provides a safe, green and efficient alternative antibody product which is suitable for the plateau yak breeding industry.

A traditional Chinese medicine composition for alleviating gastrointestinal toxic side effects caused by chemotherapy, the traditional Chinese medicine composition for daily administration is prepared from the following weight ratio of traditional Chinese medicine formula: Taizishen 20-30g, Fuling 10-15g, Fried Baizhu 10-15g, Zhigancao 5-10g, Jiangbanxia 5-10g, Chenpi 5-15g. The formula can effectively alleviate the gastrointestinal toxic side effects caused by chemotherapy, such as nausea, vomiting, diarrhea, poor appetite, etc.

A method for treating conditions of the gastrointestinal tract of a subject using a vibrating ingestible capsule ingested by the subject and activated in a targeted zone of the gastrointestinal tract of the subject. The conditions may include a sensation of gastric bloating, a sensation of straining during defecating, diarrhea and / or gastroparesis. The method is further suitable for reducing Bristol stool scores of fecal matter of the subject and for increasing a Bristol stool score of fecal matter of the subject.

The application belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating abdominal distension and diarrhea of cold-heat complex type and a preparation method thereof. The technical scheme points of the traditional Chinese medicine composition are as follows: the traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 3-6 parts of perilla, 3-10 parts of dried ginger, 3-12 parts of eucommia, 3-10 parts of scrophularia, 2-6 parts of coptis, 10-20 parts of fried coix seed, 6-10 parts of clear pinellia, 3-10 parts of dried tangerine or orange peel, 10-15 parts of poria, 6-10 parts of wheat-cooked atractylodes, 6-10 parts of vinegar-cured corydalis, 6-10 parts of vinegar-cured bupleurum, 6-10 parts of pericarpium zephyritae, 6-10 parts of chuanxiong, 6-10 parts of magnolia officinalis, 6-10 parts of fried hawthorn fruit, 3-6 parts of platycodon, and 3-10 parts of fried licorice. The traditional Chinese medicine composition and the traditional Chinese medicine water pill prepared from the traditional Chinese medicine composition have the effect of treating abdominal distension and diarrhea of cold-heat complex type.

The application provides an engineered probiotic with intracellular chimeric nanoscale enzyme, which is a probiotic modified with several antioxidant enzymes on an inner membrane; the antioxidant enzyme is composed of a metal oxide nanoscale enzyme with a particle size less than 10 nm and a targeting molecular structure and a saccharide molecular structure modified on the surface of the metal oxide nanoscale enzyme; the targeting molecular structure and the saccharide molecular structure are connected to the surface of the metal oxide nanoscale enzyme through a connecting group containing a metal ligand structure based on coordination and electrostatic interaction, and the antioxidant enzyme accounts for 5-20% of the mass of the engineered probiotic. The application also provides a method for preparing the engineered probiotic and application of the engineered probiotic in preparation of a medicine or food for preventing or treating antibiotic-associated diarrhea. The engineered probiotic can realize efficient elimination of hydroxyl radicals near a membrane induced by an antibiotic, so as to accurately inhibit a lipid peroxidation reaction and protect the integrity of a cell membrane.

The invention belongs to the technical field of additives, and particularly relates to application of osthole in preparation of an additive for preventing diarrhea of weaned piglets. Aiming at the problem that the influence of the cnidium lactone on the piglet diarrhea is not found at present, the invention firstly discovers that the piglet diarrhea can be prevented by adding the cnidium lactone into the daily ration of the weaned piglets, so that the invention provides the application of the cnidium lactone in preparing the additive for preventing the weaned piglet diarrhea. The invention further finds that the coated cnidium lactone coated by a specific method has a better effect of preventing piglet diarrhea. A brand new additive substance cnidium lactone is developed for weaned piglet diarrhea, and the cnidium lactone serving as a plant extract is safe, free of toxic and side effects, remarkable in effect of preventing weaned piglet diarrhea and suitable for large-scale application and popularization.

The invention discloses a traditional Chinese medicine navel pill for treating constipation, diarrhea and chronic enteritis and a preparation method of the traditional Chinese medicine navel pill, and belongs to the technical field of traditional Chinese medicine. The preparation method comprises the following steps: weighing the raw materials, mixing, crushing and sieving to obtain mixed medicine powder, adding honey into the mixed medicine powder, stirring and kneading until the mixture is sticky, and preparing pills. The navel pill is applied to the navel, two-way conditioning of constipation and diarrhea is achieved through the synergistic effect of traditional Chinese medicine, chronic enteritis can be treated in a targeted mode, intestinal mucosa is effectively repaired, the intestinal inflammation state is improved, the navel pill has the advantages of being safe and convenient to apply, high in bioavailability, mild and free of side effects, stimulation of oral medicine to gastrointestinal tracts is avoided, and the curative effect is good. The food is suitable for digestion function conditioning of different people.

The invention discloses a traditional Chinese medicine composition for regulating qi to alleviate pain and tonifying spleen to arrest diarrhea, a navel patch and a preparation method and application thereof, and belongs to the technical field of emplastrum, the traditional Chinese medicine composition is prepared from galangal oil, star anise oil and pericarpium citri reticulatae oil in a weight ratio of (3-5): (1-3): (2-4). The navel patch comprises a gel layer composed of an active substance and a gel matrix, and the active substance is the traditional Chinese medicine composition. The galangal oil-star anise oil-pericarpium citri reticulatae oil combination is applied to the navel patch, the galangal oil, the star anise oil and the pericarpium citri reticulatae oil have a synergistic effect to jointly achieve the effects of warming spleen and stomach for dispelling cold, regulating qi to alleviate pain and tonifying spleen to arrest diarrhea, and all active substances are from a catalog of homology of medicine and food, so that the medication safety of children is fundamentally ensured, and the worry of parents on side effects of medicines is solved.

The application provides a traditional Chinese medicine composition for treating diarrhea, and relates to the technical field of traditional Chinese medicine pharmacy. The application provides a traditional Chinese medicine composition for treating chronic diarrhea, which is prepared from madder, yuyulang, camphor tree bark, white peony root, jujube, licorice, lily, trichosanthes root and heron herb. The drugs are used together to have the functions of tonifying the spleen and stomach, astringing the lung to stop diarrhea and warming the middle and promoting qi. The traditional Chinese medicine composition can effectively relieve and improve the clinical symptoms of patients with chronic diarrhea, such as diarrhea, loss of appetite, lassitude and fatigue, and has a remarkable curative effect, so it is worthy of further clinical promotion and application.

The present application provides a kind of complex probiotic paste, which combines Enterococcus faecalis, Saccharomyces cerevisiae and vitamin B 12 Producing lactic acid bacteria of canine source, adds prebiotics, flavoring substances and auxiliary substances such as paste matrix preparation.In the paste, the viable count of Enterococcus faecalis, Saccharomyces cerevisiae and lactic acid bacteria is 1-2:1-2:1-8;Paste matrix includes fructooligosaccharide 0.5-3%, psyllium husk powder 0.1-2%, goat milk powder 2-8%, chicken liver powder 1-5%, potassium sorbate 0.5-2%, xanthan gum 1-4%, and the balance is water.The above-mentioned complex probiotic paste can be stably stored for 56 days at 4 DEG C and normal temperature dry place, has good storage stability, good safety, and can adjust intestinal flora and increase the content of intestinal lactic acid bacteria.The above-mentioned complex probiotic paste has good palatability and oral tolerance for pets such as dogs and cats, and has good therapeutic effect on DSS-induced chronic enteritis diarrhea and vitamin B 12 Deficiency.

The invention discloses bacillus subtilis for recombinant expression of a hermetia illucens HIAMP0438 gene and a construction method of the bacillus subtilis, and belongs to the technical field of gene engineering. The hermetia illucens recombinant protein used in the invention is obtained by expression of bacillus subtilis WB800N transferred into a pHT43-HIAMP0438 high-efficiency expression vector, and the pHT43-HIAMP0438 high-efficiency expression vector is obtained by a homologous recombination technology, so that high-level expression of the HIAMP0438 gene is realized, the HIAMP0438 gene can be efficiently secreted out of cells, the preparation process of the recombinant protein is greatly simplified, and the production cost is reduced. According to the present invention, the recombinant protein can significantly inhibit the growth of Escherichia coli, Salmonella and Listeria monocytogenes, and the recombinant protein can be used as the animal health product, and can be used for preventing and treating pig and chicken intestinal diarrhea caused by Escherichia coli and Salmonella and food-borne digestive tract diseases caused by Listeria monocytogenes.

The invention belongs to the technical field of medicinal and edible products, and particularly relates to a composition for improving constipation and diarrhea as well as a preparation method and application thereof. The composition for improving constipation and diarrhea provided by the invention comprises the following raw materials in parts by weight: Chinese yam, resistant dextrin, ginseng, radix ophiopogonis, poria cocos, dogwood, semen coicis, aronia melanocarpa freeze-dried powder, mulberry, radix polygonati officinalis, lycium ruthenicum freeze-dried powder, fructo-oligosaccharide and crystalline fructose. Experiments prove that through synergistic cooperation of the raw materials, the composition can effectively improve the diarrhea index of diarrhea rats, improve the intestinal barrier function, increase the villus length of small intestine tissues, reduce the depth of crypts, increase the water content of excrement of constipation mice and promote intestinal peristalsis, and has the effect of bidirectionally regulating diarrhea and constipation; the intestinal barrier function can be favorably repaired.

The application provides bacillus velezensis LW56-4 and application thereof. The bacillus velezensis is bacillus velezensis LW56-4, the classification name is Bacillus velezensis , and the preservation address is China.Wuhan.Wuhan University, and the preservation number is CCTCC NO: M 20251875. The bacillus velezensis LW56-4 has broad-spectrum antibacterial property, can reduce animal diarrhea, promote animal gastrointestinal development and improve antioxidant capacity, can effectively promote feed conversion and promote animal growth, and is an ideal substitute for aureomycin and other antibiotics.

The invention discloses a preparation method of a glucose-iron-zinc double complex, which comprises the following steps: dissolving glucose in water, adding ferrite under a stirring condition, uniformly stirring, adjusting the pH value to 7.5-8.5 by using a sodium hydroxide aqueous solution, and stirring and reacting at 70-90 DEG C for 1-2 hours to obtain a reaction solution A; adding zinc salt into the reaction liquid A, uniformly stirring, adjusting the pH value to 8.0-9.0 by using a sodium hydroxide aqueous solution, and stirring and reacting at 70-90 DEG C for 1-2 hours to obtain a reaction liquid B; and carrying out microwave treatment on the reaction liquid B, adding an ethanol water solution under a stirring condition, standing at normal temperature, separating out precipitate, and carrying out vacuum drying on the precipitate to obtain the glucose-iron-zinc double complex. Glucose sequentially reacts with ferrous salt and zinc salt, metal ions are complexed, the glucose-iron-zinc double complex is prepared, and the glucose-iron-zinc double complex is good in stability, good in solubility and easy to absorb, is added into animal feed, is high in bioavailability and can promote growth and development of animals, reduce the diarrhea rate and improve the health level of the animals.

This invention provides a probiotic composition for improving diarrhea and its uses. The probiotic composition of this invention comprises space-occupying bacteria, organic acid-producing bacteria, and oxygen-depleting bacteria, wherein the oxygen-depleting bacteria are *Weizmannii*, the organic acid-producing bacteria are *Lactobacillus* or *Lactobacillus lactis*, and the space-occupying bacteria are *Bifidobacterium*. The probiotic composition of this invention can effectively improve diarrhea and is therefore suitable for the prevention and / or treatment of diarrhea-related functional gastrointestinal disorders.

The invention relates to a fermented traditional Chinese medicine composition for preventing and treating piglet viral diarrhea as well as a preparation method and application thereof, and relates to the technical field of livestock breeding. The feed is prepared by taking traditional Chinese medicine components as basic raw materials and adding probiotics for fermentation, and the traditional Chinese medicine components comprise the following raw materials in parts by weight: 0.5-1.5 parts of cardamine violifolia dry powder, 5-15 parts of Chinese pulsatilla root, 10-20 parts of coptis chinensis, 10-20 parts of golden cypress, 10-20 parts of ash bark, 4-8 parts of turmeric, 6-10 parts of pumpkin seeds and 4-8 parts of a ginkgo leaf extract feed additive. Through cooperation of multiple components, the immunity and antioxidant functions of the body are enhanced, the structural integrity of the intestinal tract is maintained, piglet diarrhea caused by PEDV infection is effectively relieved, and growth and development of the piglet are promoted; local specialty crops are selected as medicines, and theoretical basis and practical reference are provided for deep processing of local genuine medicinal materials and PED prevention and control.

The invention provides bacillus velezensis LW56-4 and an application of the bacillus velezensis LW56-4. The bacillus velezensis is bacillus velezensis LW56-4, the classification name is bacillus velezensis, the bacillus velezensis is preserved in the China Center for Type Culture Collection on August 22, 2025, the preservation address is Wuhan University, Wuhan, China, and the preservation number is CCTCC NO: M 20251875. The bacillus velezensis LW56-4 has a broad-spectrum antibacterial property, can relieve animal diarrhea, promote gastrointestinal tract development of animals and improve oxidation resistance, can also effectively promote feed conversion and promote animal growth, and is an ideal substitute for antibiotics such as aureomycin and the like.

The invention provides a traditional Chinese medicine additive for improving the survival rate of piglets and a preparation method and application thereof, and belongs to the technical field of feed additives. The traditional Chinese medicine additive provided by the invention is Qibai tonifying powder and comprises the following raw materials in parts by weight: 20-30 parts of radix astragali, 15-25 parts of rhizoma atractylodis macrocephalae, 10-20 parts of pericarpium citri reticulatae, 10-15 parts of radix saposhnikoviae, 15-25 parts of folium cortex eucommiae, 10-15 parts of malt, 10-15 parts of cortex magnoliae officinalis, 5-10 parts of poria cocos, 5-10 parts of rhizoma dioscoreae and 5-10 parts of folium perillae. The Qibai tonifying powder provided by the invention improves the immunity of piglet organisms, promotes digestion and absorption, enhances the anti-stress ability of piglets and reduces piglet diarrhea through the synergistic effect of invigorating spleen and tonifying qi, strengthening superficies and resisting evil and strengthening tendons and bones, thereby achieving the purpose of increasing the survival rate of piglets.

1. The name of the design product: specific electromagnetic wave therapeutic instrument (HT-TDP-A). 2. The use of the design product: for physiotherapy and health care, such as auxiliary treatment for diseases such as soft tissue injury, rheumatoid arthritis, lumbar muscle strain, and pediatric diarrhea. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view. 5. The bottom of the design product is not easily visible or not visible during use, and the top view is omitted.