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1498 results about "Head and neck" patented technology

Transcutaneous photodynamic treatment of targeted cells

The present invention is drawn to methods and compounds for photodynamic therapy (PDT) of a target tissue or compositions in a mammalian subject, using a light source that preferably transmits light to a treatment site transcutaneously. The method provides for administering to the subject a therapeutically effective amount of a targeted substance, which is either a targeted photosensitizing agent, or a photosensitizing agent delivery system, or a targeted prodrug. This targeted substance preferably selectively binds to the target tissue. Light at a wavelength or waveband corresponding to that which is absorbed by the targeted substance is then administered. The light intensity is relatively low, but a high total fluence is employed to ensure the activation of the targeted photosensitizing agent or targeted prodrug product. Transcutaneous PDT is useful in the treatment of specifically selected target tissues, such as vascular endothelial tissue, the abnormal vascular walls of tumors, solid tumors of the head and neck, tumors of the gastrointestinal tract, tumors of the liver, tumors of the breast, tumors of the prostate, tumors of the lung, nonsolid tumors, malignant cells of the hematopoietic and lymphoid tissue and other lesions in the vascular system or bone marrow, and tissue or cells related to autoimmune and inflammatory disease.
Owner:LIGHT SCI ONCOLOGY

Retaining wall block

InactiveUS7168892B1Reduced and zero predetermined setbackArtificial islandsCoastlines protectionVertical planeEngineering
A retaining wall block (1) has parallel top and bottom faces (2, 3), a front face (4), a rear face (5), first and second side wall faces (6, 7) and a vertical plane of symmetry (S) extending between the front and rear faces (4, 5). The block (1) is formed as a body portion (8) including the front face (4), a head portion (9) including the rear face (5) and a neck portion (10) connecting the body portion (8) and the head portion (9). The body, head and neck portions (8, 9, 10) each extend between the top and bottom faces (2, 3) and between the first and second side wall faces (6, 7). An opening (13)′ extends through the neck portion (10) from the top face (2) to the bottom face (3), dividing the neck portion (10) into first and second neck wall members (14, 15) extending rearwardly from the body portion (8) to the head portion (9). First and second pin holes (16 and 17) are each disposed in the body portion (8) and open onto the top face (2) for receiving a pin (50, 51) with a free end of the pin protruding beyond the top face. First and second pin receiving cavities (18, 19) are each disposed in the body portion (8) and open onto the bottom face (3) for receiving the free end of a pin (50, 51) received in a pin hole (16 and 17) of an adjacent block (1) disposed therebeneath so as to interlock the blocks (1) with a predetermined setback. The neck wall members (14, 15), pin holes (16 and 17) and pin receiving cavities (18, 19) are positioned such that a first plane (P1) extending parallel to the plane of symmetry (5) passes through the first pin receiving cavity (18), first pin hole (16) and first neck wall member (14) and a second plane (P2) extending parallel to the plane of symmetry (5) passes through the second pin receiving cavity (19), second pin hole (17) and second neck wall member (15).
Owner:MELLON BANK N A

Inflatable tubular torso restraint system with pivoting upper anchor point attachment

A seat restraint system whose torso belt includes an inflatable structure that inflates upon impact to protect the occupants of a vehicle such as an automobile. The torso belt is secured to an anchor arm that is pivotally mounted on a side surface of a seat of the vehicle or a side structure of the vehicle. The anchor arm is rotationally biased to remove slack in the torso belt and locks up in the event of a vehicle crash or sudden stop. The inflatable structure is linked to a gas generator and crash sensor. The gas generator may be mounted in the seat or within the anchor arm itself. When an impact above a predetermined level of severity is detected, the gas generator is ignited, inflating the inflatable structure which contracts in length as it inflates. In a preferred embodiment, the inflatable structure is a braided tube. As the braided tube inflates, the diameter of the tube increases significantly and its length decreases significantly, due to the orientation of the fibers comprising the braided tube. The contraction in length pretensions the seat belt system by pulling any additional slack out of the seat belt systems. In a frontal impact, the inflated structure restricts the forward motion of an occupant and distributes crash loads over a larger occupant surface area to reduce both primary and secondary injuries. In a side impact, the inflated structure passes over the occupant's shoulder, restricts occupant motion, distributes crash loads and provides head and neck protection.
Owner:ZODIAC AUTOMOTIVE US
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