1564results about How to "Quick clear" patented technology

This invention describes methods of using anti-B cell antibodies, preferably anti-CD20 antibodies, and most preferably Rituximab, to treat B cell lymphomas of the brain, especially primary central nervous system lymphomas (PCNSLs), and to prevent meningeal relapse. The antibodies can be administered intrathecally alone, or in combination with other chemotherapeutics, such as methotrexate, or other anti-B cell antibodies to treat PCNSL in both immunocompromised and non-immunocompromised patients. These antibodies can also be used to diagnose patients with CNS lymphoma, especially in immunocompromised patients.

A storage area network (SAN), e.g., as described above, includes a one or more hosts digital data processors, each having a file system that effects access to one or more storage devices. Each processor is associated with multiple groups from respective levels of a hierarchy, e.g., a first processor group and a second processor group hierarchically descendant from the first processor group. A process, e.g., executing on a manager digital data processor, includes a graphical user interface that displays the processor groups as a hierarchical tree. Along, for example, with the identities of the processor groups, nodes of the displayed tree list attributes of the policy defined for each respective group.

A storage area network (SAN) has one or more host digital data processors are coupled to one or more storage devices (e.g., LUNs) by an interconnect, e.g., a fiber channel-based fabric. Switches or switch-like interfaces on the interconnect fabric define zones or regions in which certain hosts can access certain storage devices, but not other storage devices. Scanners, e.g., operating within agents associated with the hosts, collect information regarding the regions and, more particularly, the hosts, storage devices and interconnect elements that make them up. A manager operating, for example, on a further digital data processor disambiguates information from the regions and discerns the topology of the portion of the SAN spanned by the regions. Thus, it identifies as a virtual SAN elements from regions that have at least one common storage device with at least one other region.

The electrokinetic methotrexate delivery system includes at least one applicator having a multiplicity of non-conductive micro-needles carried on a non-conductive surface of the applicator. The opposite surface is formed of electrically conductive material for contact with an active electrode. The applicator includes a matrix containing a medicament, e.g., methotrexate, or a carrier therefor between the opposite surfaces. When the applicator is applied to the individual's skin with the micro-needles penetrating the skin, an electrical current is completed through the power source, the active electrode, methotrexate, or electrically conductive carrier therefor, the targeted treatment site, the individual's body, a ground electrode and the power supply, thereby electokinetically driving the medicament through the non-conductive micro-needles into the targeted treatment site.

The electrokinetic medicament delivery system includes at least one applicator having a multiplicity of non-conductive micro-needles carried on a non-conductive surface of the applicator. The opposite surface is formed of electrically conductive material for contact with an active electrode. The applicator includes a matrix containing a medicament or a carrier therefor between the opposite surfaces. When the applicator is applied to the individual's skin with the micro-needles penetrating the skin, an electrical current is completed through the power source, the active electrode, medicament, or electrically conductive carrier therefor, the targeted treatment site, the individual's body, a ground electrode and the power supply, thereby electokinetically driving the medicament through the non-conductive micro-needles into the targeted treatment site.

The present invention is drawn to methods and compounds for photodynamic therapy (PDT) of a target tissue or compositions in a mammalian subject, using a light source that preferably transmits light to a treatment site transcutaneously. The method provides for administering to the subject a therapeutically effective amount of a targeted substance, which is either a targeted photosensitizing agent, or a photosensitizing agent delivery system, or a targeted prodrug. This targeted substance preferably selectively binds to the target tissue. Light at a wavelength or waveband corresponding to that which is absorbed by the targeted substance is then administered. The light intensity is relatively low, but a high total fluence is employed to ensure the activation of the targeted photosensitizing agent or targeted prodrug product. Transcutaneous PDT is useful in the treatment of specifically selected target tissues, such as vascular endothelial tissue, the abnormal vascular walls of tumors, solid tumors of the head and neck, tumors of the gastrointestinal tract, tumors of the liver, tumors of the breast, tumors of the prostate, tumors of the lung, nonsolid tumors, malignant cells of the hematopoietic and lymphoid tissue and other lesions in the vascular system or bone marrow, and tissue or cells related to autoimmune and inflammatory disease.

An storage area network (SAN) has a manager digital data processor that includes a first element that maintains a first representation of the SAN and a second element that maintains a second representation of the SAN. The first element generates notifications of events in the SAN, e.g., addition or removal of components or relationships between components, and includes with them data pertaining to the event. The second element responds to such notifications and data by updating the second representation. That data is preferably sufficient for the second element to update the second representation without further reference to information contained in the representation.

The invention provides an improved storage area network (SAN) of the type having a digital data processor, e.g., a host, in communication with one or more storage devices, e.g., a LUN and, further, of the type having a plug-and-play (PNP) manager that generates an event in response to a change in status of at least one of the storage devices. The improvement is characterized by at least a selected process, that executes on the host (or other digital data processor) and that references at least a selected one of the storage devices using a previously assigned logical identification, e.g., a LUN ID. The improvement is further characterized by the selected process responding to an event generated by the plug-and-play by querying for information the storage device (or an interface thereto) with respect to which the event was generated. From that information, the process generates a logical identification for the device.

Novel storage area networks (SANs) and methods of operation thereof utilize a plurality of hosts coupled via an interconnect with one or more storage units. A manager device, process or other functionality in communication with a plurality of agent processes, devices or other functionality, each of which is associated with a host. The agents identify attributes of (i) their associated hosts, (ii) interconnect to which that host is coupled, and / or (iii) storage units to which that host is coupled via the interconnect. The manager responds to these attributes identified by the agents to manage the SAN. The manager can be implemented on a first digital data processor and the hosts on further digital data processors. These digital data processors can be coupled via a first network, e.g., an IP or other network, to support communications between the manager and the agents. A second network, e.g., SCSI and / or fiber channel based fabric, separate from the first network, can be utilized as the interconnect between the hosts and the storage devices.

The invention provides an improved SAN of type having one or more host digital data processors, coupled to one or more storage devices. At least a selected one of the hosts includes a file system that effects access by the host to assigned storage devices. This can be, by way of non-limiting example, an AIX journal file system, a Veritas file system, a Unix file systems using Veritas volume manager or other host platform file system that oversees file and other data accesses between the host and those assigned devices. In response to a request by (or on behalf of) the selected host for extension of the file system, a manager (e.g., executing on a further digital data processor) assigns one of more further storage devices to that digital data processor. An agent associated with the first digital data processor that responds to the assignment by extending the file system to include the assigned storage device.

The disclosure is directed to managing registration of a wireless communication device (WCD) operating in a wireless network. The WCD may support registration according to a signaling protocol, such as session initiation protocol (SIP). The WCD adjusts a registration timer based on network quality experienced by the WCD. When network quality is poor, for example, the WCD reduces the length of the registration timer. Reduced network quality may indicate that the WCD is at risk of losing network coverage. By reducing the length of the registration timer when network quality is degraded, stale registrations for out-of-coverage WCDs can be reduced. In particular, the shortened registration timer will expire more quickly, permitting the registration to be cleared more quickly. Consequently, the amount of call forwarding and other resources devoted to stale registrations can be reduced. If the WCD retains network coverage, it can maintain a registration by sending another registration request

The invention, relating to the field of environmental improvement by using environmental microorganism, particularly discloses a bacterium for reducing mercury pollution in seawater and an application thereof. The bacterium for reducing mercury pollution in seawater is Pseudomonasputida SP1, preserved in China General Microbiological Culture Collection Center (CGMCC) on Jun.1,2010 under the preservation number of CGMCC No.3887. The bacterium Pseudomonasputida SP1 can remove mercury from seawater. The use of the bacterial strain SP1 in removing mercury pollution from seawater has the advantages of high efficiency, low nutritional requirement, simple operation, high safety and the like. Compared with other processes, the cost of treating mercury pollution in seawater is greatly reduced, andthe efficiency of treating mercury pollution in seawater is raised.

A digital data processor of the type used, e.g., in management of a storage area network (SAN), executes a process (a “manager” process) to maintain a representation of the SAN topology or at least an attribute thereof. A graphical output device displays the SAN representation. A further process (a “user interface” process) controls the output device for purposes of displaying that representation. An interface element effects retrieval of the SAN representation, for example, in response to a request from the user interface process. It transmits that representation to the user interface process for display on the graphical output device.

The invention discloses an expert-system-based AID (Automated Incident Detection) system of road traffic. The system comprises a man-machine interface system, a multi-base cooperative system and an incident verification system. The multi-base cooperative system comprises a traffic information collection unit, a GIS-T (Geographic Information System for Transportation)-based database management unit, an AID algorithm automatic recognition unit, a road traffic state judgment unit and a traffic incident management knowledge base which are connected with the man-machine interface system respectively. The traffic information collection unit, the GIS-T-based database management unit, the AID algorithm automatic recognition unit, the road traffic state judgment unit and the traffic incident management knowledge base are connected with the incident verification system respectively. The invention discloses the expert-system-based AID system of road traffic, which can be used for carrying out information interaction with a driver, fast importing traffic information, further judging and verifying types and duration of incidents, and the like.

The invention discloses a device and method for laser remote removal of foreign matter on a transmission line. The device comprises a laser, a numerical control base, a light beam collimator, a visible indicating light unit, a scanning galvanometer, a distance measuring instrument, an electronic telescoping sighting device, a controller and an emitting barrel. By the adoption of the device and method, only one operator is needed, large-sized equipment or other auxiliary equipment is not needed, the operator does not have to climb a tower or a rope ladder, environment conditions such as the terrain and the line height do not needed to be considered, the device simply needs to be adjusted so as to be aligned to a target and emit lasers, the foreign matter can be removed or shot down within tens of seconds, the operator do not make any contact with facilities and equipment of the transmission line in the whole process, hot-line work can be conducted, the foreign matter on the transmission line can be remotely, rapidly and safely removed in time, and the application prospect is good.

The invention provides a storage area network (SAN) of type having one or more digital data processors coupled to one or more storage devices. At least a selected one of the hosts includes a file system that effects access by the host to assigned storage devices. This can be, for example, a conventional AIX or other host platform file system that oversees file and other data accesses between the host and those assigned devices. That host can be associated, according to these aspects of the invention, with lower and upper capacity bounds for purposes of file system extension. In response to a request by (or on behalf of) the selected digital data processor for extension of the file system, the manager assigns one of more further storage devices to that digital data processor.

A digital data processing apparatus of the type that manages a SAN includes a first queue with entries representing tasks and a second queue with entries representing data that correspond to those tasks. Data in the second queue is grouped in accord with the task to which they correspond. A manager service updates the internal representation of the SAN (e.g., the representation of the SAN topology) by executing the tasks in the first queue one at a time, for example, atomically using a single-threaded process.

The invention discloses an air purifying agent, which is composed of component A and component B. The component A is a liquid reactant prepared by percarbamide, diammonium phosphate, ammonium chloride, sodium lignosulfonate, tea polyphenol, water-soluble essence, and deionized water, while the component B is a solid reaction adsorbent prepared by a porous adsorbent, tourmaline, and a load reaction absorbent. Compared with similar products on the market, the air purifying agent of the invention has the advantages of rapid cleaning and lasting effectiveness. With the dual efficacy of sterilization and disinfection, and volatile pollution gas clearing, the air purifying agent has thorough effects and can generate objects with low toxicity or no toxicity. Characterized by easily available rawmaterials, simple preparation, low cost, and convenience for industrial production, the air purifying agent provided in the invention is proved by experiments to have a removal effect up to over 92% for high, medium and low concentration pollution.

The invention relates to a cone sand making machine and a sand making method with high efficiency, low energy consumption and high sand making yield. A big bevel gear is sleeved on an eccentric shaft sleeve which is sleeved in an axle hole in the centre of a lower shell through a copper jacket; a main shaft is positioned in the eccentric shaft sleeve through an inner copper sleeve; a spherical seat is positioned on a shell supporting ring of the positioning axle hole in the lower shell; a movable cone is sleeved on the main shaft through a spherical copper bearing bush and pushed by the main shaft to swing; a movable sleeve bushing is sleeved on the conical surface of the movable cone; an anti-wear movable sleeve is sleeved on the conical surface of the movable sleeve bushing; an inserteris sleeved on the main shaft and locked by a locking nut; an upper shell and the lower shell are connected together and three or more adjusting oil cylinders are arranged between the outer turned edges of the upper and lower shells; the inner wall of the upper shell is provided with annular spiral sawteeth which are engaged with those on the outer wall of an adjusting screw sleeve; and the adjusting screw sleeve has a double-trumpet structure, the lower trumpet-shaped wall of the adjusting screw sleeve is connected with an anti-wear fixed sleeve through a fixed sleeve bushing, and the upper trumpet-shaped wall of the adjusting screw sleeve is used for supporting a hopper assembly.

The invention relates to a compound catalytic material for purifying harmful gas. Deionized water is used as dispersant to compound nano-catalytic material, rare earth compound, p-type semiconductor, antimicrobial, plant extract and anion powder. The compound catalytic material can fast and thoroughly eliminate free formaldehyde, benzene homologue, ammonia and TVOC harmful gas. The compound catalytic material does not require ultraviolet light, has simple use and low cost and does not have toxic side effect and secondary pollution, and the purification effect can last for more than five years without rebound. At the same time, the compound catalytic material prevents bacteria, germina and mildew from invading human body, removes peculiar smell, odor, smoke, leather flavour, paint flavour and the like, increases anion and far infrared ray which are beneficial to human body and improves indoor air environmental quality comprehensively. The experiment detection shows that formaldehyde clearance rate within 24 hours is 91.6 percent; benzene clearance rate is 88.9 percent; ammonia clearance rate is 90.5 percent; TVOC clearance rate is 87.6 percent; sterilization and bacteriostasis rate is 99.99 percent; mould prevention is 0 grade; and acute oral toxicity is tested as actually nontoxic class.

The invention discloses a broad-spectrum and efficient cleaning agent for a cooling system, comprising the following components in percentage by weight: 1-5% of organic acid, 0.5-3% of metallic ion chelating agent, 0.5-2% of cleansing promotion agent, 0.1-1% of corrosion and scale inhibition dispersing agent, 0.3-5% of degreasing agent and the balance of water. The cleaning agent of the invention has safe use, the cleaning time is 1-2h, and the descaling rate is more than 90%, thereby greatly reducing corrosion and damage on the cooling system.

The present invention is concerned with delivering a pharmaceutical composition to the brain of a mammalian subject for treating brain diseases or disorders. The process includes the steps of: (i) providing a dispersion of the pharmaceutical composition as particles having an average particle size of from about 150 nm to about 100 microns, and (ii) administering the dispersion to the mammalian subject for delivery to the brain of a portion of the pharmaceutical composition by cells capable of reaching the brain. The dispersion of the pharmaceutical composition as particles, for example, can be phagocytised or adsorbed by the cells prior or subsequent to administration into the mammalian subject. The dispersion of the pharmaceutical composition can be administered to the central nervous system or the vascular system. After administration, the loaded cells transport the pharmaceutical composition as particles into the brain.

A storage area network (“SAN”) includes one or more digital data processors that are coupled for communication with one or more storage devices (e.g., LUNs) over an interconnect. The improvement provides a mechanism for hierarchically displaying, e.g., on the administrator console or other output device, portions of the SAN topology. It includes a process that generates for application to the output device a plurality of graphical object that represent “segments” of the SAN and / or components of the SAN, along with the interconnections between them. The process selectively responds to operator / administrator selection of any of the graphical objects that represent a segment by regenerating the display to depict the interconnected segments and / or components that make up that segment.

The invention discloses a portable overhead line foreign matter laser clearing device and a use method thereof. The portable overhead line foreign matter laser clearing device includes a power supply, a fiber laser, an emission device connected to the fiber laser, a controller, and an electrical platform connected to the emission device and turning and fine adjusting the emission device. According to the invention, the other auxiliary equipment is not required, climb of a pole and a tower is not needed, and an operator is not in direct contact with electric transmission line equipment; hot-line work is allowed, and foreign matters on lines can be remotely, timely, quickly, and safely cleaned; the portable overhead line foreign matter laser clearing device is easy to carry and operate, so that the time and the effort can be saved.

This invention relates to a drain plunger that snakes clogged drains at the same time that the drains are being plunged. The “snake plunger” includes a pleated bellows forming a head section which is removably coupled to a handle. Further, in one embodiment, the head and handle sections are jointly configured to release air from within the bellows while the plunger is being inserted into a basin filled with wastewater, thereby reducing or eliminating potential spillover. Further, a flexible elongated snake disposed within the interior of the bellows enters the drain as the plunger bellows is compressed. The snake is capable of dislodging and breaking up obstructions within a drain. Further, the snake may also have a hook at its lower end that is capable of snaring items causing obstructions within the drain. These features combine to create a plunger that provides a superior ability to effectively clear clogged drains.

A storage area network (SAN) of the type has a plurality of components including one or more digital data processors in communication with one or more storage devices via a switching fabric. An interface process, e.g., resident on a manager digital data processor, permits the operator / administrator to effect execution of at least a process residing on the manager and at least one process, such as a management application, residing on another SAN component.

New and improved compounds for use in diagnostic imaging or therapy having the formula M-N-O-P-G, wherein M is a metal chelator having the structure: wherein R1-R5 and FG are as defined herein (in the form complexed with a metal radionuclide or not), N-O-P is the linker containing at least one non-alpha amino acid with a cyclic group, at least one substituted bile acid or at least one non-alpha amino acid, and G is the GRP receptor targeting peptide. In the preferred embodiment, M is an Aazta metal chelator or a derivative thereof. Methods for imaging a patient and / or providing radiotherapy or phototherapy to a patient using the compounds of the invention are also provided. Methods and kits for preparing a diagnostic imaging agent from the compound is further provided. Methods and kits for preparing a radiotherapeutic agent are further provided.

An improved suction apparatus, which may be used by health care providers, emergency medical teams, or a corpsmen, to remove debris, fluid and other foreign matter from the airways and / or wounds of injured persons. The suction apparatus which includes: a venturi tube having a forward end, a rear end and an inlet, a valve located on the top rear end portion of the venturi tube, a body for housing at least one can of propellant or compressed gas, an airtight cap, and a trigger mechanism. The improved suction apparatus that forces the propellant passed the inlet of the venturi tube, wherein the inlet is located toward the distal end of the cap.