24 results about "Hematoma" patented technology

The application discloses a post-varicose vein surgery wound compression hemostasis device, which comprises a device main body for fixing on a limb, a pressure increasing module arranged on the device main body and an anti-reverse mechanism. The pressure increasing module comprises a rotating handle rotatably arranged on the device main body, a pressure push rod with a top end threadedly connected with the rotating handle and a compression pad arranged at the bottom end of the pressure push rod; the pressure push rod is slidably connected with the device main body. When the rotating handle is rotated clockwise, the pressure push rod is driven to move towards the skin side, so that the compression pad applies compression pressure on the wound. The anti-reverse mechanism is connected with the rotating handle and is used for preventing the rotating handle from being rotated counterclockwise, thereby preventing the compression pressure from being released accidentally. The device can accurately and stably maintain the compression pressure on the wound, avoids postoperative rebleeding or hematoma formation caused by pressure attenuation, and has the characteristics of convenient operation, safety and reliability.

This invention provides the application of fractalkine in the preparation of drugs for the prevention or treatment of white matter injury repair. In animal models of cerebral hemorrhage, it was found that the mass effect of hematoma in the basal ganglia and the neurotoxic products generated by its lysis lead to damage to surrounding white matter fiber bundles. Fractalkine plays an important role in regulating microglial activation after cerebral hemorrhage to promote white matter repair.

This invention relates to a deep learning-based system and method for predicting hematoma expansion in spontaneous intracerebral hemorrhage. The system includes a data acquisition module for acquiring the patient's baseline head CT image data, corresponding clinical information, and blood index data; a quantization feature calculation module for performing three-dimensional hematoma segmentation on the CT image data to obtain a three-dimensional hematoma mask; a multi-dimensional feature extraction module, including a three-dimensional morphological feature extraction sub-network and a temporal feature extraction sub-network; a feature fusion module for acquiring high-dimensional features; and a risk prediction module for outputting the risk probability of hematoma expansion based on the high-dimensional features and generating a corresponding visualized risk factor weight map. This system deeply integrates data-driven three-dimensional morphological depth features and temporal features with knowledge-driven surface regularity index and density variation coefficient quantization indicators, improving feature mining capabilities while ensuring sensitivity to key pathological morphologies, thus enhancing the robustness and accuracy of prediction.

The application discloses an intelligent indwelling needle puncture robot under ultrasonic guidance and a system thereof, and belongs to the field of medical instruments, and comprises a multi-degree-of-freedom mechanical arm system, a high-definition ultrasonic imaging module, a central processing and control unit, a man-machine interaction interface and a safety monitoring and emergency unit; the multi-degree-of-freedom mechanical arm system comprises a probe control mechanical arm and a puncture execution mechanical arm, and the probe control mechanical arm is used for clamping and adjusting the position and posture of an ultrasonic probe; the application is characterized in that the high-definition ultrasonic imaging module is used for optimizing the image, an AI blood vessel recognition and segmentation module is combined to accurately recognize the blood vessel and obtain relevant parameters, an intelligent path planning module is used for planning an optimal path for avoiding dangerous areas, and the multi-degree-of-freedom mechanical arm system is used for fine operation, so that the problem of insufficient accuracy caused by poor blood vessel conditions in manual puncture is effectively solved, the probability of repeated puncture is reduced, and complications such as blood vessel injury and hematoma are reduced.

The application belongs to the technical field of medical hydrogel, and particularly relates to a preparation method of a hydrogel for treating subdural hematoma. The preparation method of the hydrogel for treating subdural hematoma comprises the following steps: subjecting a main body material to a Fenton reaction polymerization reaction to form the hydrogel for treating subdural hematoma; and the main body material is one of acrylamide-polyethylene glycol-amino, methacrylic acid polyethylene glycol ether, alpha-acrylate base-omega-carboxyl polyethylene glycol and polyethylene glycol diacrylate. The hydrogel for treating subdural hematoma has good biological safety and can be degraded in vivo.

The application provides a cerebral hemorrhage CT hematoma segmentation and puncture channel planning system, which comprises a host computer, an image segmentation module, a target planning module, an avoidance constraint module and a channel optimization module are configured on the host computer; the image segmentation module pre-processes and segments head CT image sequence data to obtain standardized three-dimensional head CT image data and multi-dimensional anatomical structure mask data; the target planning module determines puncture target core data accordingly; the avoidance constraint module generates joint avoidance data of dangerous tissues and a range of available entry areas accordingly; the channel optimization module generates a set of alternative spatial puncture paths according to the target core data, the avoidance data and the range of available entry areas, and determines a target optimal puncture channel. The application can better balance the targeting and safety of cerebral hemorrhage puncture treatment.

The present application relates to hemodialysis wound bleeding alarm technical field, specifically, it relates to a kind of hemodialysis wound bleeding alarm device based on biosensor, it includes installation box and the fixing band being arranged below installation box, sensor alarm device is arranged on installation box, disinfection component, pressing component, air cooling component and ice compress component are arranged in installation box;Through structure integration and function synergy, bleeding monitoring, dynamic disinfection, accurate ice compress and intelligent alarm are organically combined, effectively make up the deficiencies, such as the rough management of existing technology to long-term bedridden hemodialysis patient puncture point, infection and hematoma prevention and control lag, significantly improve the safety of hemodialysis passage nursing.

The application discloses application of a MAC-1 agonist in preparation of a medicine for treating and / or relieving cerebral hemorrhage. Specifically disclosed is the use of Leukadherin-1 (LA-1) or a pharmaceutically acceptable salt, isomer or derivative thereof in preparation of a medicine for treating cerebral hemorrhage and secondary brain injury thereof. The medicine can inhibit the migration of immune cells across the blood-brain barrier, reduce cerebral edema, promote hematoma absorption and reduce neural inflammation by regulating the MAC-1-mediated immune adhesion signal pathway, thereby exerting a neuroprotective effect. Meanwhile, a pharmaceutical composition containing the MAC-1 agonist is provided. The application provides a new target and a drug development strategy for cerebral hemorrhage treatment.

The disclosure provides a kind of cerebral hemorrhage analysis method and system based on image registration, comprising: automatically segmenting cerebral hemorrhage area in brain CT image;The cerebral CT image and the segmented cerebral hemorrhage image are pretreated;Cerebral CT image is registered according to MRI template, and the deformation field is obtained;The cerebral hemorrhage image is transformed using the deformation field;Analysis patient bleeding level and the brain area involved.Use normal brain MRI image as registration template, register patient brain CT with MRI template, extract patient hematoma feature, can quickly and effectively analyze bleeding level and the brain area involved by hematoma, provide guidance for doctors, and can be used for subsequent visualization modeling, help doctors to formulate more comprehensive treatment plan.

Described are methods and systems for transcervical access of the cerebral arterial vasculature and treatment of cerebral occlusions, including ischemic stroke. The methods and devices may include methods and devices which may provide aspiration and passive flow reversal, those which protect the cerebral penumbra during the procedure to minimize injury to brain, as well as distal catheters and devices to remove an occlusion. The methods and devices that provide passive flow reversal may also offer to the user a degree of flow control. Devices and methods which provide a way to securely close the access site in the carotid artery to avoid the potentially devastating consequences of a transcervical hematoma are also described.

This utility model discloses an adjustable tubular hematoma removal device, relating to the field of medical device technology. It includes a main tube, with a suction component extending through one end and an adjustment component at the other end. An adjustment knob is located on one side of the adjustment component, and a suction tube is located at one end of the adjustment component. A handle is located on the outer side of one end of the suction tube, and a branch tube is located at the top of the middle section of the suction tube, with a sealing cap at the top of the branch tube. An injection connector is located at the other end of the suction tube. This utility model has a scientifically novel structure, enabling safe hematoma removal through the organic cooperation of the main tube, suction component, and adjustment component. The guide section and annular sealing edge on the main tube form a reliable seal with the suction needle, while the design of the branch tube and sealing cap facilitates drug injection, improving the safety and reliability of hematoma removal.

The application discloses application of Alvelestat in preparation of a medicine for treating cerebral hemorrhage. The application is based on proteomic stratification analysis of hematoma fluid of a cerebral hemorrhage patient, finds that neutrophil elastase (NE) is a key molecule in the progression of cerebral hemorrhage, and further proposes a technical scheme of taking NE as a target and using a selective NE inhibitor Alvelestat for intervention. Animal experiments verify that Alvelestat can reduce cerebral edema, promote hematoma absorption, reduce neuron apoptosis and improve neural function defects; transcriptomics reveals that it plays a protective role by inhibiting multiple inflammation and immunity related signal pathways. The application provides a new strategy for precise targeted treatment of cerebral hemorrhage, and has clear clinical conversion value.

The application discloses application of glycyrrhiza chalcone D in preparation of a drug for treating spontaneous cerebral hemorrhage and belongs to the technical field of biological medicine. The application provides application of glycyrrhiza chalcone D in preparation of a drug for treating and improving prognosis of spontaneous cerebral hemorrhage. Rat experiment results show that glycyrrhiza chalcone D can reduce hematoma of cerebral hemorrhage, reduce death of nerve cells after hemorrhage and reduce levels of inflammatory factors; cell experiment results show that glycyrrhiza chalcone D can be used as an inhibitor of ferroptosis and a COX2 inhibitor, improve ischemia and hypoxia injury of nerve cells after spontaneous cerebral hemorrhage and has a better effect than a commonly used ferroptosis inhibitor Fer-1. The application firstly reports that glycyrrhiza chalcone D is used for treating spontaneous cerebral hemorrhage and improving secondary brain injury, provides a new scheme for treatment of spontaneous cerebral hemorrhage and has a good clinical drug application prospect.

Described are methods and systems for transcervical access of the cerebral arterial vasculature and treatment of cerebral occlusions, including ischemic stroke. The methods and devices may include methods and devices which may provide aspiration and passive flow reversal, those which protect the cerebral penumbra during the procedure to minimize injury to brain, as well as distal catheters and devices to remove an occlusion. The methods and devices that provide passive flow reversal may also offer to the user a degree of flow control. Devices and methods which provide a way to securely close the access site in the carotid artery to avoid the potentially devastating consequences of a transcervical hematoma are also described.

This disclosure relates to compositions and methods for improving hemostatic efficacy in patients with intracranial hemorrhage during anticoagulation therapy with factor Xa (FXa) inhibitors. In some embodiments, the patient is selected if they exhibit a high hematoma growth rate and / or high diastolic blood pressure.

This invention provides an instrument system for minimally invasive hematoma evacuation in cerebral hemorrhage, comprising: a puncture tube with a pointed end and an open end; the pointed end having a first side hole; a puncture core for inserting into the puncture tube and sealing its hollow structure; an expansion tube for attaching to the tail end of the puncture tube after successful insertion into the hematoma cavity, and for inserting along the puncture tube into the hematoma cavity; a conformal working channel for providing a working path for the instruments during hematoma evacuation; a closing fork including a rod body and a fork fin at one end of the rod body; and a suction device including a suction device body, a curved tube, a camera, and a lighting lamp; the curved tube is mounted on the suction device body; the camera is mounted on the curved tube; and the lighting lamp is mounted on the curved tube. This invention provides an instrument system for minimally invasive hematoma evacuation in cerebral hemorrhage. By using a conformal working channel, this solution changes the traditional simple tubular structure used in endoscopic hematoma evacuation, effectively avoiding the drawbacks of interference between multiple instruments during endoscopic surgery.

The embodiment of the specification provides a method, device, medium and program product for constructing a post-percutaneous renal biopsy hemorrhage risk prediction model, and relates to the field of intelligent medical treatment. The method comprises the following steps: obtaining preoperative target parameters of training set samples, obtaining postoperative imaging data of the training set samples subjected to percutaneous renal biopsy, and extracting an outcome index for evaluating the hemorrhage risk from the postoperative imaging data, wherein the outcome index comprises (hematoma long diameter+hematoma short diameter) / 2; taking the outcome index as a verification standard, evaluating the prediction ability of the preoperative target parameters on the postoperative hemorrhage risk, and obtaining an evaluation result; and constructing a hemorrhage risk prediction model based on the preoperative target parameters according to the evaluation result. The application adjusts the outcome index for judging whether to hemorrhage and the hemorrhage risk after operation, proposes a new hemorrhage risk definition, and is used for precise prediction, real-time prediction and individualized prediction on patients who are about to perform percutaneous renal biopsy.

The present application relates to the technical field of medical devices, and discloses an adjustable femoral artery automatic pressure device, which comprises a main shell, a position adjusting assembly is installed on the top of the main shell, a moving shell is slidably connected to the middle of the main shell, a connecting column is fixedly connected to the bottom of the moving shell, an air bag is arranged at the bottom of the connecting column, a compression head is fixedly connected to the bottom of the air bag, an angle adjusting and positioning assembly is installed on the side of the main shell, a bandage rod is arranged on the side of the angle adjusting and positioning assembly, a composite sensing module is installed in the middle of the compression head, an air pipe is arranged in the moving shell, and one end of the air pipe penetrates through the connecting column and is fixedly connected to the air hole of the air bag. By sensing the physiological signals of blood flow and hematoma formation in real time, adaptive closed-loop adjustment of compression pressure is realized, so that the hemostasis accuracy, individualization level and safety of the femoral artery automatic pressure device are improved.

The utility model relates to medical instrument technical field, specifically disclose a kind of arm braking bracket for hemodialysis nursing, include: mounting mechanism and the bracket mechanism of assembly in the mounting mechanism one side, and respectively assembly in the fixed mechanism and monitoring mechanism of bracket mechanism top, the mounting mechanism includes clamp, the top of the clamp sliding installation has adjusting frame;The bracket mechanism includes the support seat of fixed installation in the adjusting frame one side, the top of the support seat is fixedly installed with multiple equidistance arrangement's clamping groove frame;The utility model can be through fixed mechanism and be fixed on support seat with patient arm, avoid the situation that arm occurs bending and moving, simultaneously, dialysis pipeline is fixed by being clamped on clamping groove frame, can prevent hemodialysis patient to move arm in dialysis process and lead to puncture needle to fall off or shift, to cause patient blood loss or hematoma influence arteriovenous fistula's use, guarantee the safety of patient.

A composition for preventing and / or improving brain dysfunction, especially Alzheimer's disease is provided. The composition includes dihydromyricetin or salts thereof, L-theanine, taurine, and cerebroside, which can enhance the intestinal stability and bioavailability of dihydromyricetin and prevent and improve brain dysfunction through multiple mechanisms such as anti-inflammation, inhibition of DNA methylation, elimination of hematoma, and removal of Aβ. In addition, the composition can be used in combination with monoclonal antibody drugs to reduce adverse reactions such as cerebral edema and cerebral hemorrhage that may occur during the treatment of Alzheimer's disease.

A method of aspirating a hematoma from a body space via a catheter coupled to a pump assembly includes advancing a tip of the catheter into proximity with the hematoma within the body space. The pump assembly includes a pump, a motor, a sensor, and a controller. The method further includes actuating the pump assembly to: operate the pump in a first mode during which the motor drives the pump at a first aspiration speed; receive at the controller a pressure signal associated with a catheter pressure from the sensor of the pump assembly; and on a condition that the catheter pressure is below a pressure threshold, operate the pump in a second mode during which the motor drives the pump cyclically between a second aspiration speed and an infusion speed such that the catheter pressure cycles between an upper pressure limit and a lower pressure limit.

This invention provides a brain tissue dilator for continuous irrigation and suction during cerebral hemorrhage surgery, comprising a sheath with a hollow, frustum-shaped structure; the outer diameter of the distal endoscopic section of the sheath is smaller than that of the proximal endoscopic section, and the sheath also has an annular sealed channel; an inner core tube; an irrigation-suction control unit including a connecting tube sealed and fixed to the outer wall of the sheath, the connecting tube having parallel and isolated inlet and outlet, the inlet being connected to the irrigation channel, the outlet being connected to the suction channel, and the inlet being connected to a positive pressure irrigation port through a first branch pipe, the outlet being connected to a negative pressure suction port through a second branch pipe; and a fixed handle located on the outer wall of the sheath away from the connecting tube. This invention allows the surgeon to flexibly adjust the irrigation and suction operations according to the nature of the hematoma and the bleeding situation, improving the efficiency of hematoma removal.

This invention discloses a minimally invasive navigation system for cerebral hemorrhage based on 3D Slicer and 3D printing, relating to the fields of surgical planning and personalized navigation technology. It includes an image error correlation analysis unit that extracts three-dimensional reconstruction features of multiple brain regions of the patient from historical data. If the patient is in a certain respiratory stage, there is a corresponding respiratory state. An LSTM-random forest hybrid model is used to evaluate error weights, and a first correlation coefficient is obtained by combining the correlation between respiration and image displacement. An error verification processing unit determines if at least two respiratory states exist when the patient is in a certain respiratory stage, extracts adjacent data, and fuses preprocessed and individual difference correction factors. A path planning, registration, and navigation fusion unit uses a 3D Slicer to segment multiple brain regions of the patient to construct a three-dimensional image. Combined with respiration and individual feature corrections, a puncture path is planned around the hematoma center, providing dual guidance through visual navigation and mechanical positioning. This invention can improve positioning accuracy.