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213 results about "Hematoma" patented technology

A hematoma (US spelling) or haematoma (UK spelling) is a localized bleeding outside of blood vessels, due to either disease or trauma including injury or surgery and may involve blood continuing to seep from broken capillaries. A hematoma is benign and is initially in liquid form spread among the tissues including in sacs between tissues where it may coagulate and solidify before blood is reabsorbed into blood vessels. An ecchymosis is a hematoma of the skin larger than 10mm.

Hemorrhagic brain injury intracranial pressure prediction and early warning system based on CT image

The invention provides an hemorrhagic brain injury intracranial pressure prediction and early warning system based on a CT image, and the system comprises a data collection module which is used for collecting the original data of a target data source of a target patient; the hybrid model comprises a 3DCNN model used for extracting hematoma spatial features of the head CT image sequence; the LSTM model is used for extracting hematoma time sequence characteristics of the physiological signals; the multi-modal fusion module is used for fusing the hematoma space features and the hematoma time sequence features and outputting hematoma fusion features; the prediction module is used for predicting an ICP sequence of the target patient in a future preset time period based on the hematoma fusion features; the self-adaptive early warning module is used for outputting a visual result based on the predicted ICP sequence in the future preset time period; and through a dynamic threshold adjustment mechanism, adjusting an early warning threshold of the target patient in combination with the case information, and triggering graded early warning in real time. Through personalized data processing and dynamic early warning, accurate, efficient and real-time patient risk management is realized.
Owner:ANKANG CENT HOSPITAL

Method and system for predicting hematoma expansion event of stroke patient

Disclosed in the present invention are a method and system for predicting a hematoma expansion event of a stroke patient. The method comprises: collecting patient data information, and performing data preprocessing; using an XG-Boost model to calculate the SHAP average value and the contribution degrees of different types of data, and extracting a feature quantity with the highest contribution degree from each type of data; performing multivariate linear regression analysis to obtain the weight of the effect of each type of data on hematoma expansion, and weighting all the feature quantities on the basis of the weight to obtain weighted feature quantities; using an extreme learning machine to predict a hematoma expansion probability; and using a northern goshawk optimization algorithm to search predicted values for the boundary of occurrence of a hematoma expansion event, and verifying the prediction accuracy. The present invention can accurately analyze and predict the expansion risk of hematoma after hemorrhagic stroke, which is crucial to early diagnosis and timely treatment.
Owner:GUIZHOU POWER GRID CO LTD

Hematoma removing device

The invention provides a hematoma removing device. The hematoma removing device comprises a catheter assembly and an endoscope assembly. The catheter assembly comprises a catheter body and a handle. The near end of the catheter body is connected with the handle; the far end part of the endoscope assembly is arranged in the far end of the catheter main body; a suction channel extending in an axial penetrating mode is arranged in the catheter assembly. The suction channel comprises a first suction channel arranged in the catheter body and a second suction channel arranged in the handle, the near end of the first suction channel is connected with the far end of the second suction channel, and the near end of the second suction channel is used for being connected with a suction device; the handle is provided with a suction adjusting hole communicated with the inside and the outside and hermetically communicated with the second suction channel. In this way, the device can achieve the purpose of controllable suction, and the clinical use requirement for suction is well met.
Owner:MICROPORT NEUROTECH SHANGHAI

Cerebral hemorrhage prognosis analysis system fusing images and clinical data

The invention discloses a cerebral hemorrhage prognosis analysis system fusing images and clinical data, and the system comprises the steps: carrying out the collection time point alignment of cerebral hemorrhage image data and clinical diagnosis and treatment data, and constructing a multi-modal time sequence association data set; hematoma region segmentation and surrounding structure compression analysis are carried out, and hematoma morphological features and placeholder effect features are extracted to form an image risk feature set; carrying out index fluctuation analysis and collaborative abnormal mode identification based on clinical data, and screening risk sensitive indexes with a linkage relationship to form a clinical risk factor set; consistency detection is carried out on the two types of risk features, deviation causes are traced, modal weight configuration is determined according to the consistency detection, differential fusion is executed, and a fusion prognosis feature vector is generated; two-dimensional risk layering of function prognosis and survival prognosis is carried out, the confidence coefficient is evaluated and predicted in combination with modal consistency and feature stability, a structured prognosis analysis report with a confidence level is output, and interpretable decision support is provided for prognosis evaluation of cerebral hemorrhage patients.
Owner:THE FIRST AFFILIATED HOSPITAL OF FUJIAN MEDICAL UNIV

Cerebral hemorrhage space positioning and prognosis prediction network system based on three-dimensional point cloud

The invention relates to the technical field of internet big data, in particular to a cerebral hemorrhage space positioning and prognosis prediction network system based on three-dimensional point cloud. The cerebral hemorrhage space positioning system comprises an image acquisition module used for acquiring a brain CT image to be processed; the offset correction module is used for performing offset correction on the brain CT image to obtain a corrected brain CT image; the hematoma region segmentation model is used for segmenting the corrected brain CT image to obtain a hematoma region; the point cloud calculation module is used for calculating three-dimensional space coordinates of hematoma voxels in a hematoma area in a brain coordinate system based on the corrected brain CT image and taking the three-dimensional space coordinates as point cloud data of the hematoma area; and the point cloud data output module is used for performing normalization processing on the point cloud data of the hematoma area to obtain hematoma three-dimensional point cloud data representing the hematoma three-dimensional space position. According to the method, an accurate and comprehensive data basis is provided for cerebral hemorrhage prognosis prediction, and the accuracy and comprehensiveness of subsequent cerebral hemorrhage prognosis prediction are improved.
Owner:THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY +1

Adjustable femoral artery automatic pressurizing device

The invention relates to the technical field of medical instruments, and discloses an adjustable femoral artery automatic pressurizing device which comprises a main shell, a position adjusting assembly is mounted at the top of the main shell, a moving shell is slidably connected to the middle of the main shell, a connecting column is fixedly connected to the bottom of the moving shell, an air bag is arranged at the bottom of the connecting column, and an air outlet is formed in the middle of the air bag. A compression head is fixedly connected to the bottom of the air bag, an angle adjusting and positioning assembly is installed on the side face of the main shell, a bandage rod is arranged on the side face of the angle adjusting and positioning assembly, a composite sensing module is installed in the middle of the compression head, and an air pipe is arranged in the movable shell. One end of the air pipe penetrates through the connecting column and is fixedly connected to the air hole of the air bag. By sensing physiological signals formed by blood flow and hematoma in real time, self-adaptive closed-loop adjustment of compression pressure is realized, so that hemostasis accuracy, individualized level and safety of the automatic femoral artery pressurizing device are improved.
Owner:SHANGHAI PUDONG HOSPITAL

Three-dimensional segmentation method for hematoma area in craniocerebral MRI scanning image

The invention relates to the technical field of region segmentation, in particular to a three-dimensional segmentation method for a hematoma region in a craniocerebral MRI scanning image, and the method comprises the steps: obtaining a target 3D image corresponding to a to-be-detected patient through craniocerebral MRI scanning; determining a T1 gradual change expression factor and a T2 gradual change expression factor of each voxel point in each preset direction according to the T1 and T2 weighted gray level change conditions of each voxel point in each preset direction; screening out a T1 main gradual change direction and a T2 main gradual change direction corresponding to each voxel point; determining a fuzzy possible factor corresponding to each voxel point and an overall main gradual change direction, and making a gradual change vertical plane to which each voxel point belongs; determining a red and swollen possible factor corresponding to each voxel point; and segmenting a target hematoma area from the target 3D image according to the position corresponding to the voxel point, the gray value and the red and swollen possible factor. According to the invention, the segmentation of the hematoma region is realized, and the accuracy of the segmentation of the hematoma region is improved.
Owner:THE FIRST AFFILIATED HOSPITAL OF XIAN MEDICAL UNIV

Cerebral hemorrhage drainage device with crushing and sucking functions

The invention relates to the technical field of medical instruments, in particular to a cerebral hemorrhage drainage device with a breaking and sucking function, which comprises a base, a support frame is fixedly mounted at the upper end of the base, a breaking mechanism is arranged on the back of the support frame, and a drainage assembly is arranged in the support frame. Through the arrangement of the crushing mechanism, blood clots and fragments can be effectively crushed and sucked out through the absorption assembly while drainage is conducted, so that it is guaranteed that hematoma is completely removed, the hematoma recurrence risk is reduced, and the drainage effect is improved; by means of the breaking and sucking function, blood clots and fragments are prevented from blocking the drainage tube, it is guaranteed that blood can flow out smoothly, and complications are reduced; by efficiently removing hematoma, compression and injury of brain tissue are reduced, nerve recovery is promoted, and the hospitalization time and rehabilitation cycle of a patient are shortened; blood clots and fragments are effectively removed, the condition of incomplete drainage or blockage is reduced, and the incidence rate of complications such as infection and hematoma recurrence is reduced.
Owner:HEFEI NO 2 PEOPLES HOSPITAL

Cerebral hemorrhage hematoma enlargement prediction system and method based on deep learning

The invention provides a cerebral hemorrhage hematoma enlargement prediction system and method based on deep learning, and the system comprises a data obtaining module which is used for obtaining a baseline CT image and clinical data of a patient; the image preprocessing module is used for carrying out standardization processing on the CT image; the feature extraction module is used for extracting image features from the CT image by adopting a deep convolutional neural network; the feature fusion module is used for fusing the image features, the clinical features and the radiology features; and the prediction module is used for predicting the hematoma expansion risk based on the fused features. The system captures 3D space information to the maximum extent by extracting the maximum lesion level, shows high reliability, high interpretability and clinical availability in the aspect of predicting hematoma expansion, is remarkably superior to prediction of clinicians, achieves reasonable consistency of prediction probability and actual probability on multiple data sets, and has good application prospects. The system can be used as a clinical decision support system and has potential to improve patient prognosis.
Owner:ZHEJIANG CANCER HOSPITAL

Cerebral hemorrhage hematoma enlargement prediction method and system, computer equipment and storage medium

The invention relates to a cerebral hemorrhage hematoma enlargement prediction method, system and device and a medium. The method comprises the following steps: acquiring baseline NCCT and CTA images of a patient; hematoma segmentation and three-dimensional reconstruction are carried out, and a key quantitative feature surface regularity index (SRI) and a density variation coefficient (DCV) are calculated; and inputting the SRI, the DCV and the clinical variables into the prediction model, and outputting the hematoma expansion risk probability. The prediction model is subjected to variable screening and strict verification, and risk visualization is realized through a column graph. The system comprises an image processing module, a feature calculation module, a prediction analysis module and a visualization module. According to the method, SRI and DCV are innovatively introduced to accurately quantify the hematoma morphology and density characteristics, and clinical variables are combined, so that the prediction accuracy and stability are remarkably improved; the efficiency is improved through AI-assisted segmentation; and the column graph enhances the model interpretability and the clinical decision support capability.
Owner:BEIJING TIANTAN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV

Pull-type midwifery assist device

The traction type midwifery assist device comprises an outer head sleeve and an inner head sleeve, and the outer head sleeve comprises an outer sleeve and an elastic clamping jaw; the inner head sleeve comprises a sleeve body, a traction pull rod and a covered edge. On one hand, on the basis of collaborative design of the elastic clamping jaws and the sleeve body, initial wrapping can be formed along with automatic outward expansion and inward contraction of the fetal head during midwifery, the edge of the sleeve opening is driven to be overturned and tightened inwards by means of the opposite acting force of the traction pull rod and the outer sleeve, dynamic gradual wrapping of the fetal head is achieved, wrapping traction can be achieved after the outer head sleeve is detached outwards, and the operation is convenient. The risk of fetal head slippage is reduced, the traction stability is enhanced, scalp hematoma, tissue injury and maternal soft birth canal injury possibly caused by traditional negative pressure suction are effectively avoided, and the safety of a mother and an infant is improved; and on the other hand, the matching of the claw tips and the covered edges is ingeniously utilized, so that the interference of the covered edges on the size change of the sleeve opening is reduced, and a smaller covering opening can be provided during inward turning covering so as to increase the covering force formed by the sleeve body and the fetal head.
Owner:TAICANG KANGHUI TECH DEV

Cerebral hemorrhage risk prediction method and system based on multi-modal learning

The invention discloses a cerebral hemorrhage risk prediction method and system based on multi-modal learning, and relates to the technical field of medical detection. The cerebral hemorrhage risk prediction method and system based on multi-modal learning comprises the following steps: S1, collecting craniocerebral multi-modal data, and preprocessing the craniocerebral multi-modal data; s2, identifying a high-gray-scale suspicious region, quantifying bleeding features of the corresponding region, and marking a suspected hematoma region; s3, the cerebral hemorrhage risk degree of the suspected hematoma area is evaluated, the risk level is judged based on the evaluation result, and a hierarchical regulation and control strategy is generated; and S4, based on the cerebral hemorrhage risk assessment results of the current assessment period and the historical assessment period, performing quantitative assessment on the cerebral hemorrhage risk level fluctuation state, and dynamically updating the risk threshold. The problems that in early cerebral hemorrhage recognition in the prior art, tiny hemorrhage lesions are difficult to find, risk dynamic evaluation cannot be achieved, and therefore clinical judgment and intervention opportunities are affected are solved.
Owner:GENERAL HOSPITAL OF PLA

Circumcision anastomat for relieving hematoma

The invention discloses a preputial circumcision anastomat for relieving hematoma, and particularly relates to a medical instrument, the preputial circumcision anastomat comprises a nail bin sleeve, a composite rubber ring which moves along with percussion is arranged in the nail bin sleeve, the composite rubber ring comprises a hollow annular rubber ring and suturing nails arranged on the annular rubber ring, and expansion parts are arranged on the two sides of the annular rubber ring; and a plurality of hollow elastic strips. The annular rubber ring is nailed into the skin in the anastomat after the ring cutting process is completed, the hollow elastic strip rebounds and turns over to be attached to the penis along with separation of the anastomat, at the moment, the annular rubber ring is wound with the elastic bandage, a wound is preliminarily pressed, hematoma is relieved, and the wound is prevented from being damaged. Then air or liquid with the low temperature is injected into the annular rubber ring through the two hollow elastic strips so as to conduct cold compress on the wound and relieve hematoma, after cold compress, the other hollow elastic strips are plugged, air or liquid continues to be injected, and therefore the two expansion parts are driven to expand, the wound is pressed, and hematoma is further relieved.
Owner:JIANGXI JUBIAO MEDICAL INSTR CO LTD

Handheld opto-acoustic multi-mode vascular puncture and tissue damage diagnosis system and device

The invention provides a handheld photoacoustic multi-mode vascular puncture and tissue damage diagnosis system and device, and belongs to the technical field of photoacoustic imaging. According to the handheld multispectral photoacoustic imaging device, elastic force feedback and blood vessel real-time development are integrated, and the puncture success rate is increased by 30%; by virtue of hemoglobin / collagen double-index imaging, the stress injury can be pre-warned 72 hours in advance; the 3D hematoma volume automatically calculates an error lt; and repeated puncture and missed diagnosis are remarkably reduced. The invention provides a quantitative evaluation and real-time navigation integrated scheme for vascular puncture and tissue damage, and is safe and efficient.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Device for assisting Ommaya capsule in extracting cerebrospinal fluid

The invention provides a device for assisting an Ommaya bag in extracting cerebrospinal fluid, and belongs to the technical field of medical instruments. Comprising an annular sterile positioning base and an injector, a through hole is formed in the middle of the annular sterile positioning base, a fixing cylinder concentric with the through hole is fixedly connected to the upper surface of the annular sterile positioning base, a stretching assembly is arranged on the right side of the fixing cylinder, and a tightening assembly is arranged in the fixing cylinder; elastic assemblies are arranged on the left side and the right side of the upper surface of the fixing cylinder. The operation sterile area is enlarged through the sterile adhesive layer and the transparent soft plate, the sterile adhesive layer composed of the nano-silver coating can achieve 72-hour continuous antibiosis, infection prevention and pathogen invasion risk reduction, the center position is located through concentric circle cross scales of the sterile semi-transparent film, guiding and visual positioning of the syringe needle are achieved, and the operation safety of the syringe needle is improved. The needle head can vertically penetrate into the center of a capsule cavity, and hematoma or capsule wall damage caused by puncture deviation is avoided.
Owner:NANFANG HOSPITAL OF SOUTHERN MEDICAL UNIV

Cerebral hemorrhage heterogeneity quantitative evaluation system based on cyclic cross-attention clustering

The invention discloses a cerebral hemorrhage heterogeneity quantitative evaluation system based on cyclic cross-attention clustering, and relates to the field of cerebral hemorrhage evaluation, and the system comprises an image segmentation module which is used for carrying out the three-dimensional segmentation of a brain plain-scan CT image through an nnU-NetV2 model, and outputting the binary masks of a hematoma region and an edema region; the feature extraction module is used for extracting high-dimensional pixel features from the mask region and generating an initial feature embedding matrix; the cyclic cross-attention clustering module is used for dynamically updating a clustering center through a multi-scale cyclic EM cross-attention mechanism and executing clustering analysis on the feature embedding matrix; the heterogeneity scoring module is used for calculating information entropy and generating hematoma and edema heterogeneity scores; and the prognosis prediction module is used for predicting the hematoma expansion risk and the neural function outcome through a machine learning model. According to the scheme, objective quantification of cerebral hemorrhage heterogeneity can be realized, and the prediction accuracy of the hematoma expansion risk and the neural function outcome is improved.
Owner:ZHEJIANG CANCER HOSPITAL

A device for visually removing hematoma

The present invention discloses a visual hematoma removal device, comprising a support body, an endoscope assembly and an outer sleeve, wherein the support body has a suction cavity inside, and the rear end of the outer sleeve is fixedly connected to the front end of the support body. The endoscope assembly comprises an endoscope and a rod body, wherein the rod body can pass through the rear part of the support body and extend into the outer sleeve via the suction cavity, and the lens of the endoscope is arranged at the front end of the rod body and extends to the front end of the outer sleeve. A suction tube is arranged on the side wall of the support body, wherein one end of the suction tube is connected to the outer sleeve through the suction cavity, and the other end is used for detachably connecting an aspirator. The visual hematoma removal device disclosed in the present invention combines endoscope technology, can achieve zero object distance imaging, and transforms the original blind operation of puncture and catheterization, hematoma suction, etc. into a visual operation, and can also suction blood and water in the brain tissue to avoid affecting the imaging effect of the lens, thereby improving the operation safety under the visual state, and also improving the accuracy of hematoma removal and the efficiency of surgery.
Owner:李广成

Methods and systems for treatment of acute ischemic stroke

Methods and devices are disclosed that enable safe, rapid and relatively short and straight access to the cerebral arteries for the introduction of interventional devices to treat acute ischemic stroke. In addition, the disclosed methods and devices provide means to securely close the access site to the cerebral arteries to avoid the potentially devastating consequences of a transcervical hematoma.
Owner:SILK ROAD MEDICAL INC

Cerebral hemorrhage accurate drainage method and system based on image density analysis

The invention provides a cerebral hemorrhage accurate drainage method and system based on image density analysis, and relates to the technical field of medical image processing and cerebral hemorrhage drainage, and the method comprises the steps: obtaining a head CT image, generating a multi-level three-dimensional density distribution diagram through a density analysis model, extracting a hematoma core region, and building a three-dimensional model; layering the hematoma core area, and determining an optimal drainage point and path; and a multi-channel intelligent drainage system is adopted for hematoma drainage, the drainage speed is adjusted according to the density sublayer parameters, hematoma volume and density distribution changes are monitored in real time, and when the current volume parameter is reduced to be below a preset volume value and the density distribution of each density sublayer tends to be uniform, accurate hematoma drainage is completed. According to the method, accurate positioning and personalized drainage of cerebral hemorrhage can be realized, and the treatment effect is improved.
Owner:DONGTAI PEOPLES HOSPITAL

Hematoma enlargement risk prediction method, equipment and medium

The invention discloses a hematoma enlargement risk prediction method and device and a medium, and relates to the field of smart medical treatment, and the method comprises the steps: inputting a baseline CT image of a target patient into a hematoma segmentation module, and obtaining a baseline hematoma segmentation result and hematoma region segmentation features of the target patient; calculating baseline hematoma radiomics characteristics of the target patient according to the baseline hematoma segmentation result of the target patient; calculating the baseline hematoma volume of the target patient according to the baseline hematoma segmentation result of the target patient; and inputting the baseline hematoma image omics features, the baseline hematoma volume and the hematoma region segmentation features of the target patient into a hematoma feature mixing module to obtain a final hematoma enlargement risk prediction result of the target patient. The risk that hematoma of the cerebral hemorrhage part expands in the future can be predicted only through the baseline CT image of the cerebral hemorrhage patient, and the prediction efficiency and accuracy are improved.
Owner:BEIJING TIANTAN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV +1

Preparation and application of novel anticancer drug TNBG-D compound

The invention provides preparation and application of a novel anticancer drug TNBG-D compound, and belongs to the field of chemical medicines. The structure of an anti-cancer drug TNBG is simplified, that is, a D ring (benzene ring) is deleted, and a series of compounds shown in the formula I or salts or stereoisomers of the compounds are obtained. The anti-cancer drug TNBG-D compound and a preparation prepared from the anti-cancer drug TNBG-D compound matched with appropriate auxiliary materials or auxiliary components have a good inhibition effect on solid tumor cells such as liver cancer, lung cancer and breast cancer and non-solid tumor cells such as hematoma, have the potential of treating solid tumors and non-solid tumors and have wide research and application prospects.
Owner:CHONGQING MEDICAL UNIVERSITY

Device for compressing forearm hematoma after coronary artery surgery

The invention provides a device for compressing hematoma of a forearm after a coronary artery operation, relates to the technical field of medical equipment, and solves the technical problem that in the prior art, uniform pressure distribution in a whole compression area is difficult to ensure in a manual bandaging process. The device for compressing the hematoma of the forearm after the coronary artery operation comprises a plate body used for supporting the arm to compress the hematoma; the at least two arc-shaped plates are oppositely and slidably arranged on the plate body and move in the width direction of the plate body; each arc-shaped plate is provided with an arc-shaped concave surface facing an arm, and the arc-shaped concave surfaces of the two arc-shaped plates are oppositely arranged; the driving assembly is connected with the arc-shaped plates and used for driving the two arc-shaped plates to get close to the extrusion arm or get away from the extrusion arm. The compression strength is controlled by adjusting the driving assembly, the occurrence of complications such as skin damage, blisters and even infection possibly caused by long-time fixed compression in traditional manual bandaging is avoided, and the extra body burden and pain of a patient are greatly reduced.
Owner:BEIJING SHIJITAN HOSPITAL CAPITAL MEDICAL UNIVERSITY

External traditional Chinese medicine composition for tendon injury, blood stasis, swelling and pain and bone impediment

The invention belongs to the technical field of traditional Chinese medicines, and provides an external traditional Chinese medicine composition for tendon injury, blood stasis, swelling and pain and bone impediment. The traditional Chinese medicine composition comprises the following components: prepared kusnezoff monkshood root, lycopodium clavatum, garden burnet, rheum officinale, radix clematidis, ligusticum wallichii, rhizoma zingiberis, angelica sinensis, Sinkiang lithospermum, peach kernel, fried gardenia, turmeric, radix angelicae pubescentis, asarum, notopterygium root, sappan wood, red paeony root, garden balsam stem, vinegar frankincense, vinegar corydalis tuber, vinegar myrrh, vinegar rhizoma cyperi, bran-fried fructus aurantii and golden cypress. The invention further discloses a preparation method and application of the traditional Chinese medicine composition for tendon injury, blood stasis, swelling and pain and bone impediment. The traditional Chinese medicines perform respective functions in monarch, minister, assistant and guide, the whole formula has the effects of promoting blood circulation to remove blood stasis, activating meridians to stop pain, dispelling wind and eliminating dampness, and reducing swelling and removing stasis, a synergistic treatment effect on tendon injury, blood stasis, swelling and pain and bone impediment is formed through a multi-target-point synergistic effect, the limitation that a traditional Chinese medicine with a single effect is difficult to comprehensively deal with is solved, and the effect of treating both symptoms and root causes is achieved; the traditional Chinese medicine composition has remarkable social benefits and clinical application value.
Owner:TIANJIN INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE HOSPITAL (TIANJIN NANKAI HOSPITAL)

Application of NR1D1 protein phosphorylation site in preparation of cerebral hemorrhage treatment medicine

PendingCN121431855ANervous disorderPeptide/protein ingredientsAntigenProtein phosphorylation
The invention discloses application of an NR1D1 protein phosphorylation site in preparation of cerebral hemorrhage treatment drugs, and belongs to the technical field of molecular biology. According to the invention, the specific phosphorylation site and phosphorylation modification level of the NR1D1 protein are determined for the first time, and the NR1D1 protein can be used as a key marker for evaluating the secondary nerve injury degree of the hemorrhagic cerebral apoplexy and developing treatment and / or alleviation of the hemorrhagic cerebral apoplexy; a specific antigen peptide and an antibody for accurately detecting the NR1D1 protein phosphorylation site are further constructed, and an efficient tool is provided for molecular evaluation of hemorrhagic stroke secondary nerve injury; meanwhile, polypeptide molecules capable of inhibiting NR1D1 protein phosphorylation are researched and developed, through the dual effects of specifically blocking the phosphorylation process and reducing protein degradation, necrosis of brain tissues around hematoma after hemorrhagic cerebral apoplexy is relieved, secondary dyskinesia is improved, and the effect of inhibiting NR1D1 protein phosphorylation is achieved. And a brand new scheme is provided for molecular evaluation and targeted intervention of hemorrhagic stroke secondary nerve injury.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Hematoma puncture equipment, hematoma form division method and device and readable storage medium

The invention provides hematoma puncture equipment, a hematoma form division method and device and a readable storage medium, the hematoma puncture equipment comprises a processor, the processor is used for executing the following steps: obtaining a plurality of cross-sectional images of a target object, each cross-sectional image in the plurality of cross-sectional images comprising a hematoma area; hematoma morphological division is carried out on a hematoma area in the first cross-sectional image to obtain a hematoma morphological distribution result of the first cross-sectional image, the hematoma morphological distribution result of the first cross-sectional image comprises at least one of a hematoma solid-state area, a hematoma liquid-state area and an edema area, and the first cross-sectional image is any one cross-sectional image in the plurality of cross-sectional images; according to the hematoma form distribution result corresponding to each cross-sectional image in the plurality of cross-sectional images, determining the volume of solid hematoma in the to-be-punctured hematoma; and according to the volume of the solid hematoma in the hematoma to be punctured, determining the dosage of the hemolysis medicine for the hematoma to be punctured. The accuracy of the dosage of the hemolytic medicine can be ensured.
Owner:WUHAN UNITED IMAGING HEALTHCARE SURGICAL TECH CO LTD

Pressurizing tourniquet

The utility model discloses a pressurizing tourniquet which comprises a tourniquet body, an air guide tube and a rubber ball. Compared with the prior art, the utility model has the advantages that: 1) rapid hemostasis: the gas filling cavity of the belt body is rapidly inflated by extruding the rubber ball, so that rapid pressurization hemostasis of a wound is realized; (2) the pressure is adjustable: the pressure in the belt body can be accurately controlled by adjusting the force for extruding the rubber ball, so that the pressurization requirements of different wounds are met; 3) firm fixation: the band body can be tightly attached to the wound through the bonding mode of the hook veneer and the loop veneer, and is not easy to loosen or fall off; 4) time is saved: the pressing time of the nurse can be obviously reduced by using the pressurizing tourniquet, so that the nurse has more time to complete other work; and (5) the risk is reduced: the risk of skin cyan and hematoma at the puncture part can be reduced through precise pressurization hemostasis.
Owner:毕青花

Scrotum support

The utility model relates to the technical field of nursing, and discloses a scrotum support which comprises a cotton cushion, a concave-convex part is arranged in the middle of the cotton cushion, the concave-convex part protrudes on the front face of the cotton cushion and is concavely arranged on the back face of the cotton cushion, extending strips are connected to the four corners of the cotton cushion, and viscose stickers are installed on the back faces, close to the ends, of the extending strips. According to the scrotum support, the cotton cushion serves as a support, after the scrotum support and the body are fixed through the extension strip, the pressurizing effect is achieved on the basis of scrotum wrapping pressure and existing gauze binding, and the applied pressure can relieve or avoid the conditions of wound bleeding and nearby hematoma.
Owner:THE FIRST AFFILIATED HOSPITAL OF JINAN UNIV

Wearable monitor for the early detection of internal bleeding events after cardiac catheterization

PendingUS20260033726A1CatheterSensorsDiagnostic testHeart catheterization
A wearable monitor is configured for early detection of internal bleeding events and particularly hematomas after vascular catheterization including cardiac catheterization. The wearable monitor is placed over an access location following the vascular catheterization procedure and the wearable monitor system periodically runs diagnostic test to detect changes in the tissue around the vascular access location. An emitter device may input an emitter input into the tissue and a detector device may then measure the emitter input after it has passed through the tissue, an emitter output. A computer may receive the data from the detector device and operate a program that determines changes in the tissue and in particular, pooling of blood in the tissue. The emitters may be electrodes that input an electromagnetic input, or an ultrasound emitter that inputs ultrasound sound waves, or a Near IR emitter that emits Near IR electromagnetic radiation.
Owner:HEMASENSE INC

Application of abscisic acid in preparation of medicine for improving secondary brain injury after cerebral hemorrhage

The invention discloses an application of abscisic acid in preparation of a medicine for improving secondary brain injury after cerebral hemorrhage, the abscisic acid can relieve neuroinflammation and improve neurological function recovery by repairing microglial cell lysosome functions, enhancing phagocytic ability and promoting hematoma removal, and a new medicine strategy is provided for cerebral hemorrhage treatment.
Owner:THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIV

A post- varicose vein surgery wound compression hemostasis device

PendingCN122251087ATourniquetsVaricose vein surgeryVaricose vein
The application discloses a post-varicose vein surgery wound compression hemostasis device, which comprises a device main body for fixing on a limb, a pressure increasing module arranged on the device main body and an anti-reverse mechanism. The pressure increasing module comprises a rotating handle rotatably arranged on the device main body, a pressure push rod with a top end threadedly connected with the rotating handle and a compression pad arranged at the bottom end of the pressure push rod; the pressure push rod is slidably connected with the device main body. When the rotating handle is rotated clockwise, the pressure push rod is driven to move towards the skin side, so that the compression pad applies compression pressure on the wound. The anti-reverse mechanism is connected with the rotating handle and is used for preventing the rotating handle from being rotated counterclockwise, thereby preventing the compression pressure from being released accidentally. The device can accurately and stably maintain the compression pressure on the wound, avoids postoperative rebleeding or hematoma formation caused by pressure attenuation, and has the characteristics of convenient operation, safety and reliability.
Owner:THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV