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322 results about "Blood circulating" patented technology

The heart is the main organ of blood circulation. Circulating blood is always in the blood vessels. Blood circulation is called a closed circulation. If we look at the explanation, then can we draw the conclusion that the blood circulating throughout the body. In a one-time supply, the blood through the heart twice.

System and method of estimating vital signs of user using artificial intelligence

ActiveUS12521068B2Image enhancementMedical imagingMedicineHistogram of oriented gradients
Disclosed is a system and processor-implemented method of estimating one or more vital signs of a user based on a video of the user by using artificial intelligence, comprising extracting a plurality of face frames and one or more time stamps from the video of the user; determining at least one region of interest (ROI) in the plurality of face frames using a histogram of oriented gradients (HOG); extracting a plurality of health indicator signals by detecting volumetric changes in a peripheral blood circulation in the at least one ROI based on a remote photoplethysmography (RPPG); and estimating the one or more vital signs of the user based on the plurality of health indicator signals and the one or more time stamps.
Owner:VASTMINDZ

Blood extracorporeal circulation device

The utility model discloses a blood extracorporeal circulation device, which belongs to the technical field of blood extracorporeal circulation equipment and comprises an inner tube and an outer tube, the inner tube and the outer tube are integrally nested, one end of the outer tube is connected with an air inlet tube, the air inlet tube is communicated with oxygen inlet equipment, and the other end of the outer tube is connected with an air outlet tube. A temperature changer and a flow speed controller are connected between one end, far away from the air outlet end, of the outer pipe and the oxygen inlet equipment; one end of the inner tube is a liquid inlet end for transporting blood, the other end of a blood inlet of the inner tube is a liquid outlet end, and the liquid outlet end is connected with a temperature sensor, an oxygen saturation sensor, a blood pump and a microembolus filter; the part, in the outer pipe, of the inner pipe is made of a gas exchange membrane material, and the liquid inlet end of the inner pipe is opposite to the gas inlet pipe of the outer pipe. The blood temperature rising process is safer, meanwhile, in the blood temperature rising process, the oxygen saturation index in the blood can be directly adjusted, the blood oxygen value is simple, convenient and controllable on the basis of convenient temperature rising, temperature control and oxygen saturation of in-vitro blood circulation are carried out at the same time, and operation is easy and safe.
Owner:GUIZHOU MEDICAL UNIV

Ex-vivo test system and test method using same

PCT designated stageWO2026029066A1Cosmonautic condition simulationsEducational modelsHuman bodyIn vitro test
An ex vivo test system 10 is constituted of a fluid circuit that circulates a prescribed circulation liquid by simulating the blood circulation state of a human body, and comprises a circulation liquid maintenance unit 17 that maintains, in the same manner as the blood environment in vivo, chemical factors in the circulation liquid, which affect the performance evaluation of a test object S. The circulation liquid maintenance unit 17 comprises: a replenishing liquid unit 23 that maintains the chloride ion concentration and protein concentration of the circulation liquid at desired values by injecting a replenishing liquid composed of an electrolyte-free isotonic solution into the fluid circuit; and a carbon dioxide supply unit 24 that maintains the pH of the circulation liquid at a desired value by supplying carbon dioxide into the fluid circuit, the state of the circulation liquid being maintained while compensating for the effect of moisture loss during circulation of the circulation liquid.
Owner:WASEDA UNIV

Household portable blood sugar and uric acid two-in-one human body detection device

The invention belongs to the technical field of medical detection equipment, and particularly relates to a household portable blood sugar and uric acid two-in-one human body detection device which comprises a detector shell. A display screen and a detector body are installed on the top and one side of the inner wall of the detector shell respectively, test paper is connected to one side wall of the detector body, a blood sampling pen is connected to one side wall of the detector shell in a magnetic adsorption mode, and an auxiliary assembly used for promoting blood circulation of the hand is further embedded in the inner wall of the detector shell. After the blood sampling pen is magnetically separated from the detector shell, one end of the blood sampling pen punctures the finger of a detected person, so that the detected person conveniently drips blood generated by the punctured finger onto the test paper, and after the test paper is in contact with the detector body, the blood of the detected person is analyzed; the analyzed blood glucose value and uric acid value of the detected person are displayed through the display screen, and the purpose of blood glucose and uric acid two-in-one detection is achieved.
Owner:JIANGXI ZHANGHU MEDICAL TECH CO LTD

Oxygenator with gas compartment heater

An oxygenation device for use with extracorporeal blood circulation is disclosed. The device includes an oxygenator housing having a blood inlet end cap having a blood inlet opening, a blood outlet end cap having a blood outlet opening, and a gas collector housing between the blood inlet opening and the blood outlet opening. The gas collector housing defines a gas compartment having a gas inlet chamber with a gas inlet port and a gas outlet chamber with a gas outlet port. Heating devices are disposed against the gas collector housing and include a first heating device in the gas inlet chamber and a second heating device in the gas outlet chamber. During operation of the oxygenation device, the heating devices heat the gas compartment.
Owner:CBM LIFEMOTION SRL

Coronary artery hemodynamic information prediction method, device, equipment, medium and product

The invention discloses a coronary artery hemodynamic information prediction method, device and equipment, a medium and a product, and relates to the field of biomechanics, and the method comprises the steps: obtaining clinical data, and segmenting the clinical data to obtain a coronary artery three-dimensional model and a heart three-dimensional model; constructing a human body blood circulation system lumped parameter model; determining a personalized human body blood circulation system lumped parameter model of the patient after assignment; constructing a 0-3-dimensional myocardial mechanical coupling model; constructing a first database; obtaining personalized systolic function parameters and diastolic function parameters of the patient based on the first mapping network; constructing a blood vessel 0-3-dimensional coupling model; constructing a second database; obtaining personalized coronary flow field information of the patient based on a second mapping network; the personalized coronary flow field information comprises a pressure field, a velocity field and concentration polarization characteristics of low-density lipoprotein on a blood vessel wall surface. Through network architecture innovation, the bottleneck of the model in the aspects of efficiency and personalization is solved, and the diagnosis precision of the coronary heart disease is improved.
Owner:ZHEJIANG NORMAL UNIV +2

Catheter pump outlet structure and auxiliary blood circulation device

The application provides a conduit pump outlet structure and an auxiliary blood circulation device. The conduit pump outlet structure comprises a diffuser arranged in an outlet frame, the outlet frame comprising a fixing ring and at least two struts, the diffuser comprising a hub and at least two guide vanes connected to the hub, the number of the guide vanes being consistent with the number of the struts, the profile edge of the guide vanes comprising a root surface and a tip surface, the root surface being the connecting surface of the guide vanes and the hub, and the tip surface being the outer surface away from the hub; the struts have the same outer profile as the tip surface of the guide vanes; when the diffuser is arranged in the outlet frame, the guide vanes and the struts are arranged one by one, so that the tip surface and the inner wall of the struts are arranged in close contact. By using the application, the resistance of blood output is reduced, and the blood pumping efficiency is improved.
Owner:SUZHOU HEARTHILL MEDICAL CO LTD

Insole with magnetic therapy massage function

The utility model provides an insole with a magnetic therapy massage function, which belongs to the technical field of health care products and comprises an insole component, a bottom pad, a separator arranged at the top of the bottom pad and an insole surface integrally formed with the outer surface of the bottom pad. The massage assembly comprises a first massage convex block fixedly mounted on the outer surface of the insole surface, and a second massage convex block, a third massage convex block, a fourth massage convex block and a fifth massage convex block which are sequentially and fixedly mounted towards the front foot sole part through the first massage convex block. According to the utility model, the six groups of massage bumps are distributed according to the acupuncture points of the sole and are matched with the outline and radian of the sole, and the massage particles distributed on the outer surface can accurately stimulate the acupuncture points, so that the blood circulation of the foot is effectively promoted, the swelling and aching pain of the foot caused by long-time walking or standing are relieved, and more serious foot diseases are prevented; magnetic therapy sheets can be embedded to achieve magnetic therapy stimulation, promote qi and blood circulation of meridians and collaterals and maintain overall health of the body.
Owner:ZHEJIANG JIANCHENG SHOES GRP CO LTD

Pulsation anti-load trousers and simplified air bag heart assisting device

According to the pulsating anti-load pants and the simplified air bag heart assisting device, by adding the anti-load clothes and the pulsating and blood pumping functions of the anti-load pants, the standing anti-load pants during cruising are changed into pulsating pressurizing pants with time control air valve pulsating type inflation and deflation or left and right air bags alternately inflated and deflated; the thick and long blood vessels of the lower limbs and the one-way valves on the inner walls of the thick and long blood vessels of the lower limbs are extruded to pump blood to become a second external heart; a simplified air bag heart assisting device is a pulsating anti-load pants reduced configuration scheme, outer-layer clothes and pants of anti-load pants are removed, and the simplified air bag heart assisting device is simplified into a crus air bag or a thigh and crus communicated air bag sewed nylon fastener tape device, and left and right leg air bag air conveying rubber pipes are connected with two electromagnetic three-way valves respectively and then are combined through rubber pipes to be connected with an air pump. Two-way power-on and power-off of a time relay are used for controlling left and right electromagnetic valves or improved valves to be connected with air bags, an air pump and an external tee joint, so that left and right leg air bags are inflated and deflated in turn; the invention can be used as heart-aiding anti-load trousers and heart-aiding fitness equipment, and can improve the blood circulation of the human body.
Owner:江洪

Conveniently wearable stroke rehabilitation waistband

This utility model discloses a convenient wearable stroke rehabilitation belt, relating to the field of rehabilitation fixation technology. It includes a lifting plate, with a rehabilitation fixation belt snapped onto the top surface of the lifting plate. A limiting component is installed on the top surface of the lifting plate, restricting the position of the rehabilitation fixation belt. Multiple sets of heat therapy patches are provided on the inner side of the rehabilitation fixation belt. In use, the easy assembly and disassembly of the rehabilitation fixation belt and the lifting plate facilitates daily use by patients to assist in rehabilitation. Simultaneously, the synergistic effect of the electrical stimulation patches and the heat therapy patches provides thermal therapy and nerve electrical stimulation to the lumbar muscles, improving blood circulation and enhancing rehabilitation outcomes.
Owner:四川亦锦生物科技有限公司

Hemodialysis patient vascular health assessment and arteriovenous fistula intelligent nursing system

PendingCN122460908ADecreased mean arterial pressureArteria iliaca interna
The present application relates to the technical field of blood monitoring, in particular to a vascular health assessment and intelligent nursing system for hemodialysis patients. The degree of venous reflux obstruction is determined based on the change trend and degree of venous pressure data within each dialysis period, and the degree of inconsistency between the change trends of venous pressure data and transmembrane pressure data. The degree of arterial supply obstruction is determined based on the change trend and degree of arterial pressure data within each dialysis period. The suspected internal fistula obstruction period is determined based on the change trend of the degree of venous reflux obstruction and the degree of arterial supply obstruction. The nursing intervention prompting degree of the patient to be tested is determined based on the relationship between the blood flow data and arterial pressure data of each dialysis stage of the patient to be tested within the suspected internal fistula obstruction period, and the blood flow data of the non-dialysis stage. The internal fistula nursing scheme is determined. The present application realizes early warning of internal fistula dysfunction based on the change of venous and arterial pressure of the blood circulation loop during dialysis.
Owner:THE SECOND AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIVERSITY

Portable hot compress medicine carrying device for treating temporomandibular arthropathy

The invention discloses a portable hot compress medicine carrying device for treating temporomandibular arthropathy, which comprises a main body part provided with a placing cavity; the medicine carrying assembly is arranged in the placing cavity; the ear hook is connected to the side of the main body part so as to be hung on the ear, so that the medicine carrying assembly faces the temporomandibular joint; the medicine carrying assembly comprises a medicine box, a sponge layer and a graphene heating layer, the sponge layer is arranged between the medicine box and the graphene heating layer, and liquid medicine in the medicine box is conveyed to the graphene heating layer arranged towards the temporomandibular joint through the sponge layer; the graphene heating layer is electrified to emit far infrared waves, so that blood circulation of the temporomandibular joint area is promoted through heat radiation, and percutaneous release of liquid medicine is enhanced. According to the medicine carrying device, through heat radiation of the graphene heating layer, local blood circulation of the temporomandibular joint is improved, skin permeability is improved, and medicine penetrates through the skin to enter subcutaneous tissue or muscular tissue.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL

Myasthenia gravis eye muscle fatigue degree evaluation system based on infrared thermal imaging

This invention relates to the field of medical data mining technology, specifically to a system for assessing eye muscle fatigue in myasthenia gravis based on infrared thermal imaging. First, the degree of blood circulation impairment is determined based on the temperature changes of pixels in various directions within a speckled region. Then, based on the number of speckled regions and the concentration of hot spots, a speckled region influence value reflecting local blood circulation and metabolic abnormalities is determined. Next, combining the degree of blood circulation impairment, the speckled region influence value, and the speckled region distribution, a comprehensive reference degree of eye muscle fatigue is determined. Furthermore, considering the distribution of speckled regions under the influence of grease, the degree of blood circulation impairment, and the characteristic that the reference degree of eye muscle fatigue typically does not change, a corresponding grease influence value is determined. Thus, combining the reference degree of eye muscle fatigue and the grease influence value allows for a more accurate determination of the eye muscle fatigue assessment value, resulting in better assessment of eye muscle fatigue in myasthenia gravis based on this value.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Decompression bracelet

1. Name of the design product: decompression bracelet. 2. Use of the design product: used for massage to relieve anxiety and promote local blood circulation. 3. Design points of the design product: in shape. 4. Picture or photo that best shows the design points: perspective view.
Owner:FOSHAN KUMEI SILICONE RUBBER PROD CO LTD

MOTOR VEHICLE INCLUDING AN AUTOMATIC FOOTREST FOR A VEHICLE PASSENGER

The invention relates to a motor vehicle comprising at least one passenger seat, the vehicle comprising a footrest (FR) configured to activate the blood circulation of a passenger, characterized in that the vehicle comprises a controller (C) configured to communicate with the footrest (FR) and with a health data collection means (MC) configured to measure at least one health data point among the passenger's blood pressure, heart rate, perspiration rate, and / or body temperature, said footrest (FR) comprising a vibrator and / or a sliding device capable of activating automatically when insufficient blood circulation of the passenger is detected, the footrest (FR) being positioned opposite the passenger seat. The invention further relates to a method for activating a vibrator and / or a sliding device of a footrest (FR) as previously described. Abstract figure: Fig. 1
Owner:STELLANTIS AUTO SAS +1

Split animal lung thoracoscopic surgery simulation training model and use method thereof

The invention discloses a split animal lung thoracoscopic surgery simulation training model and a use method thereof. The split animal lung thoracoscopic surgery simulation training model comprises a simulation surgery unit and a power unit. The simulation operation unit is composed of an outer cover, a lung containing cavity and a bottom plate, is provided with an intercostal channel and a liquid taking and discharging opening, and is further provided with an artery, a vein, a trachea, a water injection and overflow plate penetrating connector and a detachable water leakage partition plate. The power unit comprises an air pump, a blood circulation motor, a water adding motor, a blood powder water tank and a water purifying tank to form an air path, blood powder water circulation and a perfusion and overflow loop; the gas circuit is provided with a pressure valve, a dryer and a mucus buffer box, and the drainage loop is provided with a normally-open solenoid valve. During use, low-flow blood circulation and pressure-limiting ventilation self-inspection are performed before an operation; during operation, a gas path is closed for endoscopic operation, and exudation / bleeding is recovered to a blood powder water tank; and after operation, ventilating and filling pure water until overflowing, judging air leakage by bubbles underwater and judging errhysis by color difference. The model is high in simulation degree, intuitive in interpretation, safe and easy to maintain.
Owner:GUANGZHOU MEDICAL UNIV

Heart postoperative wound nursing equipment

The invention discloses cardiac postoperative wound nursing equipment, and belongs to the technical field of cardiac intervention postoperative nursing. A connecting and supporting mechanism for supporting and mounting the arm fixing mechanism is mounted on the mounting frame; an arm fixing mechanism for positioning and fixing arms of a patient is mounted on the connecting and supporting mechanism; a locking mechanism used for being connected with a sickbed is installed on the installation frame. The connecting and supporting mechanism comprises a hinging assembly, a limiting assembly and an arm rotating assembly; the number of the limiting assemblies is two. The limiting assembly and the mounting frame are both connected with the hinge assembly; the limiting assembly is connected with the arm rotating assembly; the arm rotating assembly is connected with the arm fixing mechanism. By means of the mode, a patient can freely change the bending degree between the large closed forearms when the arms are fixed, the comfort degree of the patient is improved, and meanwhile blood circulation of the arms of the patient is facilitated.
Owner:CHINESE PEOPLES LIBERATION ARMY ARMY SPECIAL MEDICAL CENTER

Post-skin-grafting supporting device with physiotherapy healing promoting function

According to the post-skin-grafting supporting device with the physiotherapy healing promoting function, a physiotherapy healing promoting patch part and a silica gel frame can be attached to the skin around a wound, an internal elastic net provides traction force, a healing medicine bag is loaded with multiple healing promoting medicines and permeates into the wound through a bottom through hole, and a conveying nozzle is arranged to facilitate medicine supplement; the graphene heating sheet is electrified to generate heat which is transferred through the heat conducting plate to accelerate wound blood circulation. A breathable adhesive tape of the traction belt assembly adheres to peripheral skin of a wound, one end of a cotton belt is connected with a silica gel frame, and the other end of the cotton belt is connected with a traction supporting force trimmer through a braided rope. The trimmer winds the braided rope through the knob to pull the skin, skin grafting pulling is reduced, the traction force can be flexibly adjusted through a ratchet wheel and pawl structure, the knob can be reversely rotated to loosen the braided rope by pressing the pawl, the pawl is loosened for fixation after proper adjustment, and healing after skin grafting is effectively promoted.
Owner:AFFILIATED HOSPITAL OF NANTONG UNIV

Improved trop2 conjugated biological molecules, pharmaceutical compositions and applications thereof

The present disclosure provides linker-payload conjugates including a bioorthogonal group and a hydrophilic moiety. The improved linker-payloads for antibody conjugation and improved antibody drug conjugates (ADCs) exhibit greater stability in blood circulation and enhanced drug delivery and drug release efficiencies in target cells. The present disclosure also relates to antibodies and antigen-binding fragments thereof targeting TROP2, as well as pharmaceutical compositions including TROP2 ADCs. Also described herein are methods of using TROP2 ADCs for treatment of subjects associated with pathological conditions.
Owner:OBI PHARMA INC +1

Emergency lower limb physical cooling device

PendingCN122440392AVeinEmergency treatment
The application discloses a physical cooling device for lower limbs in emergency treatment, which comprises a rack, a driving assembly, a motion assembly, a limb bracket and a linkage assembly. The crank disc of the motion assembly is connected with the driving shaft. The connecting rod and the rocker are driven by the pin shaft with adjustable crank radius, so that the limb bracket installed at the free end of the rocker reciprocates and drives the lower limbs of the patient to make passive movement. The protrusion of the linkage assembly is fixed on the crank disc and intermittently opens the micro switch to control the alcohol spray of the alcohol atomization source to be sprayed from the nozzle installed on the limb bracket, and the spraying direction is directed to the popliteal fossa position. The lower legs of the patient are driven by the motion assembly to make periodic reciprocating swing, the muscle pump effect is utilized to promote the venous return and local blood circulation of the limbs, the blood flow of the large blood vessel area at the popliteal fossa is accelerated, and the intermittent alcohol mist spraying of the linkage assembly is matched, so that the heat exchange efficiency between the blood and the cold medium is improved.
Owner:THE 923RD HOSPITAL OF THE CHINESE PEOPLES LIBERATION ARMY JOINT LOGISTICS SUPPORT FORCE

Resuscitation device used after small animal anesthesia

The utility model belongs to the technical field of medical experiment auxiliary equipment, and provides a resuscitation device for small animals after anesthesia, which comprises a control base, a touch screen arranged on one side of the control base, a box body fixedly mounted at the top end of the control base, a support frame fixedly mounted in the box body, and a sponge cushion layer arranged at the top end of the support frame; the multiple sets of massage rollers are arranged in the supporting frame, blood circulation and drug metabolism of the small animals are promoted, hard contact with the bodies of the small animals is avoided through slow rotation of the massage rollers and the buffering effect of the damping springs, blood circulation and lymphatic reflux are accelerated through mild physical stimulation, and the small animals are prevented from being injured. By means of the design, the recovery speed is increased, and side effects caused by medicine residues are reduced.
Owner:HEBEI MEDICAL UNIVERSITY

Linearly reciprocating blood pump

Described herein are pumps that linearly reciprocate to assist with circulating blood within the body of a patient. Red blood cell damage may be avoided or minimized by such linear pump movement. The linearly reciprocating movement may also generate a pulsatile pumping cycle that mimics the natural pumping cycle of the heart. The pumps may be configured to reside at various body locations. For example, the pumps may be situated within the right ventricle, the left ventricle, the ascending aorta, the descending aorta, the thoracic aorta, or the abdominal aorta. In some instances, the pump may be deployed within the venous circulation. In other instances, the pump may reside outside the patient.
Owner:SUMMACOR INC

Blood purification device

A blood purification device (1) comprises: a blood purifier (3) capable of purifying blood; a blood circuit (2) including an arterial-side blood circuit (21) which has an arterial-side puncture needle (211) attached on the distal end thereof, and a venous-side blood circuit (22) which has a venous-side puncture needle (221) attached on the distal end thereof; an impedance measurement unit (5) including an oscillator (53) that applies an alternating-current voltage across an arterial-side electrode (51) provided to the arterial-side blood circuit (21) and a venous-side electrode (52) provided to the venous-side blood circuit (22), the impedance measurement unit being capable of measuring frequency characteristics of the impedance between the arterial-side electrode (51) and the venous-side electrode (52); and a puncture determination unit (72) for determining, on the basis of the measured frequency characteristics of the impedance, whether a patient has been punctured normally. The blood purification device also comprises a frequency range determination unit (70) for determining the frequency range of the alternating-current voltage applied by the oscillator (53) in accordance with the liquid in the blood circuit (2).
Owner:NIKKISO CO LTD

Adjustable external application bellyband based on pancreatitis

The invention discloses an adjustable external application bellyband based on pancreatitis, and belongs to the field of medical instruments, the adjustable external application bellyband comprises a medicine application section, a bandage and a connecting assembly, and the connecting assembly is located on one side of the medicine application section and used for being connected with the bandage; the adjusting assembly is used for adjusting the tightness degree of the bandage according to the waistline size, the abdominal swelling degree and the comfort degree of the patient, and it is ensured that the bellyband can stably wrap the abdomen without generating too tight pressure feeling; then the pressure of the affected part corresponding to the medicine application section is adjusted in a targeted mode through an adjusting assembly in the medicine application section, and the situation that due to too small pressure, a medicine bag is not tightly attached, the medicine effect is lost, or due to too large pressure, pain of a patient is caused, and local blood circulation is affected is avoided; finally, an abutting assembly on an adjusting assembly mounting frame is matched with a clamping assembly, the medicine bag is firmly connected to the pancreatitis affected part in an abutting mode, it is guaranteed that the medicine bag is in tight contact with the skin all the time, and stable conditions are provided for medicine ingredient permeation and treatment effect exertion.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL

Multispectral health monitor (G11)

ActiveCN309958463SMassageBlood circulating
1. Name of the product in this design: Multispectral Health and Wellness Device (G11). 2. Application of this design: This design is intended for use as an instrument for phototherapy and massage to promote blood circulation and maintain health. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D rendering 1.
Owner:SHENZHEN URION TECH

Adjustable dynamic fixing brace for postoperative rehabilitation of cervical vertebra

PendingCN121868023AChiropractic devicesRoller massageDynamic fixationBlood circulating
The invention relates to the technical field of medical instruments, in particular to an adjustable dynamic fixing brace for postoperative rehabilitation of cervical vertebrae, which comprises a base and a chair body, and further comprises a hydraulic pressure rod, a hydraulic pressure rod, a hydraulic pressure rod and a hydraulic pressure rod, the backrest mechanism is arranged at the top of the base; water in the storage box is heated to 35-40 DEG C through a thermocouple and driven by a pump body to be conveyed to a box body of the power assembly through a conveying pipeline, after blades are pushed to rotate, hot water flows into a liquid passing groove of the heat preservation mechanism through a first backflow pipeline, the flowing time of the hot water in the bottom plate is prolonged through the liquid passing groove distributed in a winding mode, the temperature of the bottom plate is evenly increased, and the heat preservation effect is improved. The detachable ground mat attached to the feet of the patient can transfer heat to the feet mildly, blood circulation is promoted, used hot water flows back to the storage box through the second backflow pipeline to be circularly heated, the comfortable temperature is continuously maintained, the problem of foot cold caused by long-time cervical traction in winter is effectively solved, and the comfort degree in the treatment process is improved.
Owner:ANSTEEL GRP CORP GENERAL HOSPITAL (ANSTEEL EMERGENCY CENT)

A highly safe tumor treatment preparation based on a prodrug-enzyme-neutralizing antibody three-system and a preparation method and application thereof

The application discloses a high-safety tumor treatment preparation based on a prodrug-enzyme-neutralizing antibody three-system, and a preparation method and application thereof. The preparation comprises three core components: (a) a prodrug, which is coupled by an anti-tumor drug (such as doxorubicin) and cephalosporin; (b) an activating enzyme, such as beta-lactamase, which is specifically expressed in the tumor by phage, catalyzes the hydrolysis of the prodrug, and releases the active drug; and (c) a neutralizing antibody, such as an anti-doxorubicin monoclonal antibody, which can specifically bind and neutralize the active drug overflowing into the blood circulation. The application first integrates the precise killing strategy of "prodrug-local activation" and the safety strategy of "neutralizing antibody-systematic protection" into a complete treatment closed loop, utilizes the "differential neutralization" characteristics of the anti-doxorubicin antibody, effectively protects normal tissues from toxic damage under the premise of not affecting the local efficacy of the tumor, and significantly improves the therapeutic index of the chemotherapy drug, reduces the side effects such as cardiotoxicity and bone marrow suppression, and provides a new paradigm with high efficiency and safety for tumor treatment.
Owner:GUANGZHOU XINGLIN NO 1 BIOTECHNOLOGY CO LTD

Massage heating pad

The utility model relates to the technical field of heating pads, and discloses a massage heating pad which comprises a frame, a shell is fixedly connected to one side of the frame, two massage modules distributed in a mirror image mode are fixedly connected to the interior of the shell, and an inner layer liner, a heating layer and an outer layer liner are fixedly connected to the interior of the frame. And a plurality of electrode plates which are arranged in a rectangular array are fixedly connected to one side of the outer-layer liner. According to the massage heating pad, two therapies of massage and electrical stimulation are combined, the massage module acts on muscular tissue in a mechanical mode, blood circulation is promoted, muscular tension is relieved, weak current emitted by the electrode plates can directly stimulate acupuncture points of the human body, meridians and collaterals are further promoted to be smooth, and the effects of relieving pain and relaxing the mind and body are achieved; the dual therapies complement each other, the curative effect can be remarkably improved, and due to the fact that the electrode plates are arranged in a rectangular array mode, accurate stimulation can be conducted on different acupuncture points or pain areas.
Owner:NINGBO KANGHONG ELECTRICAL APPLIANCE CO LTD