Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

68 results about "Pain sensation" patented technology

Pain sensation - a somatic sensation of acute discomfort; "as the intensity increased the sensation changed from tickle to pain". painful sensation, pain. somaesthesia, somatesthesia, somatic sensation, somesthesia - the perception of tactual or proprioceptive or gut sensations; "he relied on somesthesia to warn him of pressure changes".

Pain management with stimulation subthreshold to paresthesia

ActiveUS20100249875A1Minimizing complicationsMinimizing effectsSpinal electrodesArtificial respirationHypesthesiaSide effect
Devices, systems and methods are provided for treating pain while minimizing or eliminating possible complications and undesired side effects, particularly the sensation of paresthesia. This is achieved by stimulating in proximity to a dorsal root ganglion with stimulation energy in a manner that will affect pain sensations without generating substantial sensations of paresthesia. In some embodiments, such neurostimulation takes advantage of anatomical features and functions particular to the dorsal root ganglion.
Owner:TC1 LLC

Method and apparatus for selective control of nerve fibers

A method and apparatus particularly useful for pain control by selectively blocking the propagation of body-generated action potentials travelling through a nerve bundle by using a tripolar electrode device to generate unidirectional action potentials to serve as collision blocks with the body-generated action potentials representing pain sensations in the small-diameter sensory fibers. In the described preferred embodiments there are a plurality of electrode devices spaced along the length of the nerve bundle which are sequentially actuated with delays corresponding to the velocity of propagation of the body-generated action potentials through the large-diameter fibers to produce a "green wave" effect which minimizes undesired anodal blocking of the large-diameter fibers while maximizing the collision blocking of the small-diameter fibers.
Owner:MEDTRONIC INC

Non-Invasive Neural Stimulation

InactiveUS20090149782A1Ultrasound therapyElectrotherapyPersistent painMedicine
The present invention is a system for the non-contact stimulation of excitable tissue. A primary purpose is reducing the perception of pain in those people who suffer from persistent pain. Apparatus is described for adjusting the position of the stimulation region.
Owner:COHEN DONALD

Method and apparatus for veterinary RF pain management

A method and apparatus for reducing chronic pain in animals by radio frequency (RF) neuromodulation of peripheral nerves of the animal is disclosed. The method, using the disclosed apparatus, comprises the steps of attaching active and dispersive percutaneous probes at respective active and dispersive locations relative to a peripheral nerve of the patient associated with the pain to be reduced; generating a first pulsed RF signal for coupling to the active and dispersive probes to verify the location of the peripheral nerve; and generating a second pulsed RF signal for coupling to the active and dispersive probes to modify propagation of pain sensation in the peripheral nerve without ablation thereof. In one embodiment of the apparatus, the active percutaneous probe includes an RF cannula having a conductive spatulate blade conformably attached to a dorsal side of a curved, blunt-ended tubular tip portion of the RF cannula. In another embodiment of the apparatus, a dispersive percutaneous probe includes a pair of 22 gauge needles connected to ground return conductors. In yet another embodiment of the apparatus, a pulsed RF generator is modified to provide specific outputs adapted to the neuromodulation of peripheral nerves in veterinary patients.
Owner:CLASSEN ASHLEY M +1

System to create arbitrary waveforms using an external inductor and an implantable medical device

An implantable stimulation system includes a stimulation current generator encased in an implantable housing, one or more stimulation leads to deliver therapeutic stimulation from the generator to target patient tissue, and inductive elements arranged to condition the stimulation for delivery to the target tissue with increased efficiency and reduced pain sensation. The inductive elements are arranged external to the housing and integral with one or more of a stimulation lead or an external component of the housing, such as a header. The inductive elements serve to condition therapeutic stimulations such that varying the output of the generator allows the system to deliver arbitrary effective waveforms to the target tissue.
Owner:PACESETTER INC

Reduced-pain allergy skin test device

An allergy skin test device is disclosed that causes less pain than commonly used devices that include multi-point sharp puncture heads. The allergy skin test device incorporates multiple dull pressure heads distributed amongst the sharp multi-point sharp puncture heads, each dull pressure head activating a neurological pain gate that reduces pain sensation typically caused by the neighboring multi-point head when it engages the skin.
Owner:LINCOLN DIAGNOSTICS +1

Vibrative body sensation induced potential stimulation system

The body sensation induced potential stimulation system based on vibration includes monolithic microcomputer, pulse shaping circuit, power amplifier circuit, state display, body sensation stimulation generator, and fixer. The monolithic microcomputer calculates to synthesize pulse drive signal with specific frequency and adjustable duty ratio, so that the body sensation stimulation system generates vibration waveform with envelope simulating true touch sensation, vibration sensation and pain sensation to reach the aim of effective body sensation stimulation. The present invention controls the generation of body sensation stimulation signal simulating touch sensation, vibration sensation and pain sensation, and may be used in the application research of body sensation induced potential SEP. The present invention has the features of high integration degree, adjustable strength, high performance / cost ratio, etc. and may be widely applied.
Owner:INST OF PSYCHOLOGY CHINESE ACADEMY OF SCI

Trp inhibitors and uses thereof

InactiveUS20120148604A1BiocideNervous disorderTransient receptor potential channelTRPC4
The present invention, relates to methods including compounds, derivatives, antibodies, interfering RNA, biologies, polypeptides, dominant negative effectors, and their use in the treatment of neuropathic pain by inhibition of transient receptor potential (TRP) channels. In another embodiment, this invention relates to inhibitors, antagonists, and agonists of TRPC4. TRPC4 therapeutic agents and modulators include but are not limited to small molecule inhibitors, compounds, amino acid derivatives, polypeptides, RNA interference agents, natural chemicals, ligand derivatives, and ions. TRPC4 therapeutic agents and modulators are developed for the treatment of neuropathic pain, including but not limited to pain sensations such as nociception, hyperalgesia, allodynia, and loss of sensory function.
Owner:POSEIDA THERAPEUTICS INC

Electronic stimulation system and device thereof for dorsal root ganglion

An electronic stimulation device for electrically stimulating at least one dorsal root ganglion with relative low pain sensations without generating relative much sensations of paresthesia comprises at least one electronic stimulation unit. The electronic stimulation unit includes at least one first electrode and at least one second electrode, and it delivers a high-frequency electrical stimulation signal to impel the first electrode and the second electrode to generate an electric field. The range of the electric field covers the dorsal root ganglion, and the electric field strength ranges from 100 V / m to 1000 V / m.
Owner:GIMER MEDICAL CO LTD

Enhancing optical radiation systems used in dermatologic treatments

The disclosed technology can be used to enhance the brightness of a multi-wavelength light source incorporated within a dermatologic system to thereby increase its efficiency and reduce the power and filtering requirements of the system resulting in an overall reduction in the size and cost of the system. The disclosed technology can enhance a user's experience with the dermatologic system by reducing the user's pain sensation when using the system during a dermatologic treatment and / or facilitating the movement of the system across a skin surface under treatment.
Owner:SHASER

Intelligent patient-controlled analgesia pump

The invention discloses an intelligent patient-controlled analgesia pump and relates to medical equipment. The intelligent patient-controlled analgesia pump consists of a drive device and an infusion device which is arranged inside the drive device, and is characterized in that: the drive device consists of a pump body, a connector jacket, a liquid crystal display, a key, a bubble sensor, a PCA key and a PCA jack; the connector jacket is arranged at the upper end of the pump body; the liquid crystal display and the key are arranged on the pump body; the bubble sensor is arranged on one side of the pump body; and the PCA key is connected to one side of the pump body through the PCA jack. The intelligent patient-controlled analgesia pump can automatically adjust the basic amount of infused liquid medicine according to the frequency of using the PCA by the patient for analgesia after operation so as to reach the optimal medicine doses for different patients, relive the pain and improve the nursing quality without medical care personnel.
Owner:江苏三和生物工程股份有限公司

Adhesive bandage with reduced pain during removal

InactiveCN101495077AEasy and fast tear-offReduce pain side effectsBandagesAdhesive bandageElectrical and Electronics engineering
The present invention relates to an adhesive bandage with reduced pain during removal, whose flat strip substrate has a sticking front, a non-sticking back and four sides. And, both areas of said sticking front and non-sticking back are greater than those of four sides; The feature is: a strip of non-glued area is disposed between both of opposite parallel lengthwise lateral sides and two strips of glued area are parallel juxtaposed on both lengthwise sides of said non-glued area respectively on said sticking front, wherein a pair of glue-less indentations are formed on both end sides of said non-glued area but not adjacent said glued area of said strip substrate and being flush with both crosswise end sides; When the sticking front of the strip substrate sticks and presses on the skin epidermis around the wound, the middle non-glued area does not contact and stick on the skin epidermis S; Hence, when said adhesive bandage is to be ripped off upon changing medical dressing, our fingers can take anyone glue-less indentation on the strip substrate as grip fulcrum for lifting up to achieve the purpose of tearing off said strip substrate from the skin epidermis with effect of no painful feeling by such tearing off action.
Owner:陈 崇钦 +1

Preparation method of lidocaine carbonate injection

The invention discloses a preparation method of a lidocaine carbonate injection. The preparation method comprises the following processes of solution preparation, pH adjustment, filtration and disinfection. The preparation method is characterized in that the filtration process comprises filtering a solution subjected to pH adjustment by a cellulose acetate microfiltration membrane having an aperture size of 0.22 micrometers, filtering the solution by a PVDF microfiltration membrane having an aperture size of 0.22 micrometers until clarification, filling the filtered solution in an ampoule, and carrying out sealing. The solution subjected to pH adjustment is filtered by the cellulose acetate microfiltration membrane having an aperture size of 0.22 micrometers, then is filtered by the PVDF microfiltration membrane, and is subjected to high-pressure steam sterilization at a high temperature of 121 DEG C so that impurities and bacteria in the solution are removed thoroughly and preparation bioavailability and absorption effects are improved. The preparation method has simple processes and is convenient for operation. The lidocaine carbonate injection obtained by the preparation method is safe and effective in clinical use and has small side-effects. Compared with the existing lidocaine carbonate injection, the lidocaine carbonate injection obtained by the preparation method obviously shortens onset time and pain sensation disappearance time and prolongs anaesthesia duration time.
Owner:TIANSHENG PHARMA GROUP

Asepsis patch for postoperative wound pain relieving

The present invention discloses aseptic sticking membrane agent used for postoperation wound acesodyne, which consists of an anti-sticking layer, a drug-storing layer and a back lining layer. The drug-storing layer consists of framework material and microsphere loaded with local anesthetic, and the framework material is macromolecular polymer with film forming ability. The aseptic sticking membrane agent used for the postoperation wound acesodyne of the present invention can realize the uniform, lasting and slow release of the drug to achieve the lasting acesodyne effect, because the local anesthetic is wrapped inside the microsphere by the micro spheroidization technology. The aseptic sticking membrane agent used for the postoperation wound acesodyne of the present invention is used for the postoperation wound acesodyne, which can ensure that a patient does not have obvious painful feeling during the wound healing period.
Owner:TIANJIN UNIV

Negative pressure and intense pulsed light (IPL) collaboratively-operated medical and beauty equipment

The invention relates to negative pressure and intense pulsed light (IPL) collaboratively-operated medical and beauty equipment which comprises a skin acceptance cabin, a negative pressure generator and an intense pulsed light system, wherein the negative pressure generator is connected to the skin acceptance cabin through a pipeline; and the intense pulsed light system is arranged above the skin acceptance cabin and can generate pulsed light, of which the wave length is 490 nm-1200 nm. The medical and beauty equipment, by utilizing ingenious combination of the negative pressure adsorption principle and the intense pulsed light, reduces damage to epidermal tissues, reduces aching feeling of patients to a great extent, reduces risks when used on a human body, improves comfortableness of the patients and reduces damage of the intense pulsed light to the epidermal tissues.
Owner:BEIJING ANCHORFREE TECH

Puncture needle robot for pain sensation treatment

The invention discloses a puncture needle robot for pain sensation treatment. The robot comprises a base, a lifting mechanism arranged on the base, a passive arm arranged on the lifting mechanism andan RCM mechanism arranged at the front end of the passive arm; the puncture needle robot comprises a base, a lifting mechanism arranged on the base, a passive arm arranged on the lifting mechanism andan RCM mechanism arranged at the front end of the passive arm. The passive arm includes a plurality of passive locking joints and a connecting rod arranged between the plurality of passive locking joints. The passive arm of the invention has a plurality of degrees of freedom, can increase the flexibility of the operation, and makes the operation of the complex operation simple; The passive locking joint of the invention has sufficient rigidity and locking torque, and can ensure the positioning accuracy of the front end RCM of the passive arm; The robot can give play to the advantages of stable operation and accurate positioning of the robot to ensure the operation quality. The installation angle of the passive arm and the lifting column of the invention can realize high-precision adjustment and ensure the precision and quality of the surgical treatment. The robot has the advantages of simple structure, good use effect and good application prospect.
Owner:SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI

Methods and compositions for studying, imaging, and treating pain

Saxitoxin analogue compounds, compositions, pharmaceutical compositions, methods of synthesis of saxitoxin analogues, methods of imaging, methods of treatment, including methods of treating pain, are provided. Saxitoxin (STX), gonyautoxin (GTX), and zetekitoxin, and variant STX compounds bind to sodium channels and are effective to reduce or block flow of sodium ions through such channels. Such channel block affects nerve and muscle action, and may be effective to reduce or block pain sensations, relax muscles, reduce muscle spasm, and reduce wrinkles. STX analogue binding to sodium channels may also be useful to locate, image, or mark sodium channels, and so be useful in studying sodium channels and sodium channel disorders, and in the diagnosis and treatment of patients suffering from sodium channel disorders. In embodiments, the variant STX compounds include conjugates having increased serum half-life as compared to STX when administered to a subject. In embodiments, the present disclosure provides a method for alleviating pain in a subject in need of treatment, the method comprising administering to the subject an effective amount of a saxitoxin analogue compound, or a pharmaceutically acceptable salt, isomer, tautomer or prodrug thereof, whereby pain in said subject is alleviated.
Owner:THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV

Medical bed for fracture rehabilitation of children

The invention discloses a medical bed for fracture rehabilitation of children and relates to the technical field of medical treatment of the children. The medical bed comprises a bedstead, wherein twosides of the bottom of the bedstead are fixedly connected with telescopic bed legs; two sides in the bedstead are fixedly connected with slide tracks; hydraulic telescopic rods are fixedly connectedwith the positions, above the slide tracks, on two sides of the inner wall of the bedstead and fixedly connected with sliders through output rods; the bottoms of the sliders are glidingly connected with the slide tracks; the tops of the sliders are rotationally connected with support rods; the ends, away from the sliders, of the support rods are rotationally connected with a head bedstead and a foot bedstead respectively. The medical bed for fracture rehabilitation of the children achieves the purpose of automatic adjustment of bed height and guardrail position, a user adjusts the bed height conveniently, the bed is also conveniently used by a medical worker, a patient can call the medical worker in case of emergency by means of different calling modes, pain due to long-time bed rest is reduced, and bed rest comfort of the children is improved.
Owner:常州朝旭企业服务有限公司

Tactile sensor for neurology department

The invention discloses a tactile sensor for neurology department. The tactile sensor comprises a main body, wherein a top frame is fixedly connected with the top of the main body; a side wall of thetop frame is fixedly connected with a buckle hammer; the side wall of the main body is fixedly connected with a syringe; the tactile sensor relates to the technical field of medical equipment. According to the tactile sensor for the neurology department, a motor drives a rotary screw rod to do intermittent forward movement and a patient is subjected to staged acupuncture, so that a condition thatan acupuncture speed is too rapid is avoided; when the patient feels painful, the running of the device can be stopped in time, the accuracy of an examination result is improved and the aim of alleviating pains of the patient is realized; the aims that a contact needle is wiped through alcohol and disinfected in a stretching or retracting process, bacteria on the surface of the contact needle is reduced and the contact needle is convenient to use are realized; when a protection pad is in contact with skin of the patient, a pressure switch is switched on and acupuncture can be carried out; whenemergency conditions occur, the pressure of the pressure switch is reduced, the pressure switch is switched off and the motor stops moving, so that the aim of improving the safety of tactile examination of the neurology department is realized.
Owner:田士宏

Bionic pain-free syringe needle

The invention discloses a bionic pain-free syringe needle, and belongs to the technical field of medical instruments. A needle tip, a syringe and a connector are structurally integrated, the cross section of the syringe is circular, a curve A is formed on the upper surface by a connecting line between a and b, the syringe under an overlooking angle takes a longitudinal axis c-c as a center, a sliding rail I and a sliding rail II are symmetrically arranged on two sides of the syringe under the overlooking angle, a starting point in the sliding rail I is e, a terminal point in the sliding rail Iis f, a curve B formed by a connecting line between the e and the f, a starting point in the sliding rail II is c, a terminal point in the sliding rail II is d, and a curve B' is formed by a connecting line between the c and the d. A mathematical expression of the curve A is y1=3.115*10<-5>x<3>-0.04847x<2>+27.36x-4688, wherein 350<=x<=410. The mathematical expression of the curve B is y2=5.407*10<-5>x<3>-0.07635x<2>+38.27x-6025, wherein 340<=x<=400. The bionic pain-free syringe needle simulates curve characters of a bee needle portion of a bumblebee, so that the needle of a syringe is designed and injected into the skin of a human body in a pain-free manner, and the pain of the human body can be relieved.
Owner:JILIN UNIV

Automatic acupoint-applied directly-pressurizing micro-needle and application method thereof

The invention relates to the field of medical technology, in particular to an automatic acupoint-applied directly-pressurizing micro-needle and an application method thereof. The automatic acupoint-applied directly-pressurizing micro-needle comprises a skin feeling and contact piece and an assembly housing structure. The bottom of the skin feeling and contact piece is adhered to a micro-needle positioning piece. One side, departing from the skin feeling and contact piece, of the micro-needle positioning piece is adhered to a button positioning piece. A viscous force connecting piece is arranged between the micro-needle positioning piece and the button positioning piece. One side of connection between the viscous force connecting piece and the micro-needle positioning piece is equipped witha medical adhesive tape. The middle part of the medical adhesive tape is equipped with a micro-needle structure in an adhering manner. The middle part of one side, departing the micro-needle positioning piece, of the button positioning piece is equipped with a pressure button in an embedding manner. By pressing the pressure button on the adhesive tape, a needle point vertically pierces at one time and is closely adhered and fixed by the adhesive tape. Before the needle point pierces, the skin feeling and contact piece touching the skin excites a pressure sensation nerve receptor and inhibitsa pain sensation receptor in order to relieve pains. After the adhesive tape is attached to the skin, the adhesive tape automatically separates from the micro-needle. The operation step of imbedding aneedle during treatment is simplified.
Owner:陈宏

High-precision pressure detection device of pain sensation of human body

The invention belongs to the field of medical auxiliary instrument. Via the pressure detection device, quick and precise detection of pain sensation pressure can be achieved. The pressure detection device is a measuring device made of a micrometer, a spring and a contact head cap. When a cap cover contacts the skin of the people, after the spring is in the natural state, a knob of the micrometer is twisted to allow the spring to be in the compression state so as to transmit the force to the human body via the contact head cap to stimulate the human body. When the body pain threshold value is achieved, the human body feels pains, and the number, i.e., the deformation quantity of the spring, on the micrometer can be read. By converting the number into pressure, the pressure of the pain sensation of the human body can be precisely measured.
Owner:NORTHEAST NORMAL UNIVERSITY

Complementary gain pain-killing medicine

The complementary gain pain-killing medicine consists of vitamin B6, anisodamine and Tiapride. The medicine has outstand curative effect on vascular headache and excellent curative effect on the sciatica, trigeminal neuralgia and dizziness syndromes. The medicine features that it can regulate the biochemical change of vascular headache, block the conductance of pain sensation impulsion, improve microcirculation and eliminate sickness caused the prostaglandin and arachidonic acid evolution process to result in lasting pain-killing effect. The medicine has simple preparation process, is safe, non-toxic and low in cost, and may be used widely in treating vascular headache, sciatica, trigeminal neuralgia, dizziness syndromes, etc.
Owner:王月樵

Bone marrow extraction device with puncture point positioning function for medical bone marrow puncture

PendingCN113693644AEasy to extract jobsFunctionalAnaesthesiaSurgical needlesHuman bodySurgery
The invention discloses a bone marrow extraction device with a puncture point positioning function for medical bone marrow puncture. The bone marrow extraction device comprises: a base structure, wherein a rotating puncture mechanism is arranged at the upper end of the interior of the base structure; a bone marrow extraction structure which is arranged on one side of the outer wall of the rotating puncture mechanism; a bone marrow collection test tube which is arranged on one side of the outer part of the bone marrow extraction structure in a threaded manner; and a wound disinfection structure which is fixed to one side of the interior of the base structure. According to the bone marrow extraction device, the bone marrow extraction position is fixed through the binding belt, the device has the functions of disinfection, anesthesia and the like while having the puncture marrow extraction function, the two procedures of marrow extraction and anesthesia are conducted at the same time, the needle receiving frequency of a patient is reduced, the bone marrow extraction operation is more convenient, the miniature rotating tube rotating at a high speed is used for breaking and puncturing a hard human body, so that the marrow taking speed is increased, and the pain of a patient is relieved.
Owner:刘媛
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products