15 results about "Pain sensation" patented technology

The invention provides a traditional Chinese medicine hot compress bag for relieving endoscopic postoperative pain and a preparation method of the traditional Chinese medicine hot compress bag, and belongs to the technical field of traditional Chinese medicine hot compress bags. The invention provides a traditional Chinese medicine composition for regulating spleen and stomach and activating meridians to stop pain. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 70 to 100 parts of liquorice root, 20 to 80 parts of rhizoma zingiberis, 20 to 80 parts of fructus evodiae, 20 to 80 parts of semen raphani, 20 to 80 parts of malt, 20 to 50 parts of cassia twig, 20 to 50 parts of fructus perillae and 10 to 30 parts of black prepared common monkshood daughter root. The traditional Chinese medicine composition provided by the invention has remarkable effects of regulating spleen and stomach and activating meridians to stop pain, and can play roles of astringing and inducing astringency, tonifying middle-Jiao and Qi, and dispersing blood stasis and relieving pain after being prepared into a traditional Chinese medicine Reyan bag. Due to the design of the self-heating device, the heating time of the traditional Chinese medicine hot compress bag is long, the heating power maintaining time is long, transdermal absorption of medicines in the traditional Chinese medicine hot compress bag is facilitated, and the pain after the endoscopic surgery can be remarkably relieved.

The utility model discloses an operating bed for PICC (Peripherally Inserted Central Catheter), which relates to the technical field of medical instruments and comprises an operating bed body, a rubber sleeve is arranged on the operating bed body, a first mother Velcro is fixedly mounted on the rubber sleeve, a first son Velcro matched with the first mother Velcro is integrally formed on the outer wall of the rubber sleeve, and a second son Velcro matched with the second mother Velcro is integrally formed on the outer wall of the rubber sleeve. Before an operation, a patient wears the rubber sleeve and adjusts the rubber sleeve to be comfortable, the rubber sleeve is fixed to the upper portion and the lower portion of the elbow through the first mother hook-and-loop fastener and the first child hook-and-loop fastener, bending of the arm is limited, and the rubber sleeve is fixed to the upper portion and the lower portion of the elbow through the second mother hook-and-loop fastener and the second child hook-and-loop fastener. The steel tube assists in keeping the arm vertical, the attention and pressing requirements of medical staff on arm displacement are reduced, puncture deviation caused by patient collision or pain sensitive elbow displacement is prevented, and the operation success rate is increased.

The invention relates to medicine, and more particularly to algology, and can be used in the treatment of pain. The present method includes oral administration of a pharmaceutical composition. Administration begins with a minimum single dose comprising: 1 drop or granule of the composition, dissolved in 15 ml of water, per 10 kg of the patient's weight. The minimum single dose is administered every 15 minutes. An individually tailored single dose is determined by adding up the minimum doses of the composition which induce a subjective sensation of a decrease in pain. The composition is administered in the individually tailored single dose at a dosage frequency of not more than 8 times a day on the first day and not more than four times a day on the second and subsequent days. The pharmaceutical composition contains equal quantities of Eupatorium perfoliatum in a 3D dilution, China officinalis, Secale comutum, Arnica montana in a 3C dilution, Rhus toxicodendron in a 4C dilution, Aconitum napellus, Belladonna, Bryonia alba, Ipecacuanha, Nux vomica in a 5C dilution, Mercurius solubilis in a 6C dilution, Abrotanum, Gallicum acidum, Heloderma suspectum, Senecio aureus in a 7C dilution, and Stramonium in a 9C dilution. The invention provides for a significant decrease in the pain sensations experienced by the patient, irrespective of the source of and reasons for the pain.

A virtual reality (VR) system for generating pain sensations in VR environments using thermal grill illusion (TGI), comprising a VR device and a wearable thermos-haptic device with a thermoelectric stimulative module for inducing TGI-based pain sensations, a heat sink coupled to the module for temperature regulation and stabilization, and a thermocouple for monitoring and controlling temperature changes.

A system, method and device for early detection of lower extremity injuries in patients with neuropathy who may have impaired pain sensation. The system comprises a sensor apparatus with multiple sensors that measure physiological parameters at specific locations on a patient's foot and lower limb. A connected computing entity receives and analyzes sensor data to identify potential injury markers such as temperature anomalies, tissue oxygenation changes, and swelling. Using machine learning algorithms that improve through continuous training, the system determines injury likelihood based on personalized baselines and historical data at a patient level. The computing entity generates an intuitive user interface displaying injury likelihood assessments for healthcare providers. This technology enables early intervention through non-invasive monitoring, potentially preventing serious complications in a vulnerable populations.

The application discloses a kind of based on pressure pain sensation's bionic flexible touch sensor and robot active protection method, it is related to bionic robot flexible sensing and safety protection field.The sensor adopts DIW integrated printing process, including flexible silica gel base, cross intersection row and column conductive grid and spherical cap micro convex pressure resistance sensing unit, no layering, full flexibility, can adapt to robot complex curved surface whole body.It is based on the critical pressure intensity of sensor material destruction as benchmark, constructs three-stage progressive quantization bionic pain sensation system, through pain sensation value driving robot executes graded protection action, core through expanding force area to eliminate structural risk from root;While constructing whole body partition density bionic skin system, fusion foot bottom pressure and gyroscope data realizes walking balance adjustment.The application gives consideration to sensing accuracy and engineering cost, greatly improves the bionic sensing ability of humanoid robot, operation safety and structure life.

This invention provides the application of berberine II derivatives in the preparation of drugs for treating diabetic foot, belonging to the field of biomedical technology. This invention is the first to discover that berberine II derivatives can significantly improve symptoms such as decreased motor / sensory nerve conduction velocity and loss of pain sensation in diabetic foot model rats, and promote wound healing in the affected foot. Berberine II derivatives hold promise for further development and research as a novel drug for treating diabetic foot.

The invention relates to the technical field of biological medicines, in particular to application of a CCR1 / 5 inhibitor Met-RANTES in inhibition of pathological pain of trigeminal nerves. According to the invention, CCR1 / 5 is taken as a therapeutic target of chronic pain, and a medicine which is remarkable in analgesic effect, small in side effect and capable of relieving chronic pain and improving pain mood is developed by combining the pharmacological function of an inhibitor Met-RANTES of CCR1 / 5. The Met-RANTES inhibits a central nervous system chemokine receptor CCRR1 / 5 in a targeted manner in a regular nasal administration manner, so that pathological mechanical pain-sensitive response and accompanying negative emotion caused by chronic compression of trigeminal nerves can be remarkably relieved, and pain feeling is relieved. In addition, the analgesic effect of the drug combination of the Met-RANTES and the carbamazepine is more obvious than that of the drug combination of the Met-RANTES and the carbamazepine which are independently used. The nasal delivery mode enables the medicine to directly reach the central nervous system, and reduces side effects of the whole body.

The present invention provides a highly realistic upper limb nerve injury examination skill training simulation model. A pain sensation examination needle is used to prick the highly realistic human upper limb model to examine the patient's pain sensation. The pain sensation in the distribution area of the damaged nerve will necessarily decrease. Through the microcomputer monitoring controller, voice prompts and different colors of indicator lights are issued to judge the damaged upper limb nerve location. This achievement is used in medical colleges and teaching hospitals to train medical students and in-service medical staff in upper limb nerve injury examination skills, which can significantly improve the teaching effect. A highly realistic upper limb nerve injury examination skill training model, which comprises: a highly realistic human upper limb model, a microcomputer monitoring controller, and a pain sensation examination needle. It is characterized in that: four highly realistic human upper limb models (1-1, 1-2, 1-3, 1-4) are each provided with a simulated skin (2), a subcutaneous tissue-muscle layer (3), and a simulated bone (4). Under the simulated skin (2), an upper layer conductive metal mesh electrode (B1 / B2 / B3 / B4) and a lower layer conductive metal mesh common electrode (A) isolated by an insulating layer (5) are arranged. The present invention can significantly improve the quality of skill training.

The utility model discloses a trainer for feeling rehabilitation. The trainer comprises a main body seat capable of being transferred in a handheld mode; the tactile modules are different in surface roughness, can be touched by hands of a patient during use and are used for tactile and pain rehabilitation, and the tactile modules are inserted into the corresponding positioning grooves in a matched mode in a replaceable mode; the cold module is used for being touched by the hand of the patient during use, is used for temperature sense rehabilitation and provides cold stimulation; the heat module is used for being touched by the hand of the patient during use, is used for temperature sense rehabilitation and provides heat stimulation; and the balls have different diameters and are used for stimulating the deep and shallow composite feeling of the patient. In the process of feeling rehabilitation, a patient can continuously touch the touch module, the cold module and the hot module with hands, and the touch module, the cold module and the hot module are comprehensively used, so that the superficial feeling of the patient is stimulated; a patient pokes the balls with different sizes by hands to roll in the corresponding track grooves so as to stimulate the deep and shallow composite feeling of the patient.

The invention relates to the technical field of traditional Chinese medicine plasters, in particular to a pain-relieving acupoint plaster and a preparation method thereof. The medicine component is prepared from the following raw materials: frankincense, myrrh, scorpion, centipede, corydalis tuber, clove, elecampane and cassia twig; according to the pain-relieving acupoint plaster disclosed by the invention, the traditional Chinese medicine components are scientifically screened and the ratio is optimized, and the components play specific functions in the pain-relieving process and form a synergistic effect. Boswellia carteri and myrrh are used as classic analgesic compatibility and have the effects of promoting blood circulation to remove blood stasis and promoting qi circulation to relieve pain, and effective components of frankincense and myrrh can permeate into local tissues to relieve qi and blood stasis of painful parts, so that pain is relieved from the source; the scorpio and the centipede have the effects of activating meridians to stop pain, and the active ingredients of the scorpio and the centipede can act on a pain sense conduction pathway to block the transmission of pain signals, so that the scorpio and the centipede have a remarkable inhibition effect on intractable pain.

The invention relates to a stretching-pain perception system based on a multi-gate synaptic transistor and a preparation method and application thereof, and belongs to the technical field of artificial sensory neuron and neuromorphic calculation. The system comprises a crack type strain sensor and a multi-gate synaptic transistor, the strain sensor adopts a metal / elastic composite material double-layer conductive structure, and has high sensitivity and a continuous conductive path; the multi-gate synaptic transistor takes an electrolyte material as a gate medium, takes a metal oxide as an electrode and a channel, and is provided with a bottom gate and a side gate. The strain sensor is connected with the bottom grid and the side grid through a voltage division circuit, and dynamic integration and processing of stretching signals are achieved by regulating and controlling different grid voltages. According to the invention, multi-stage mode conversion from conventional stretching perception to pain early warning is realized, the method is suitable for biological nerve simulation systems such as electronic skin, intelligent artificial limbs and bionic robots, and the bottleneck problem that an existing pain perception system is difficult to realize multi-signal fusion and dynamic regulation and control is solved.

The application discloses application of rapamycin in preparation of a reliever of opiate drug tolerance caused by an anti-angiogenic drug, the reliever and a medicine, and relates to the technical field of medicine application. It is found that a TSC1-mTOR-autophagy axis plays a role in opiate drug tolerance caused by an anti-angiogenic drug, and the specific embodiment is that the anti-angiogenic drug can cause a decrease in TSC1 content, an mTOR / RPS6 pathway is activated, thereby autophagy flow is blocked, and pain sensation is enhanced; therefore, the opiate tolerance condition can be relieved by adjusting the mTOR / RPS6 pathway through rapamycin.

The present invention relates to a body-inserted massage structure and a body-inserted massage device, belonging to the technical field of massage, and solving the technical problem of high pain sensation in the massage actions of massage elements in the prior art. A carrier having a cylindrical region and a sunk groove region, and the carrier can be entirely inserted into a cavity-shaped massage part to be massaged; the cylindrical region is an approximately cylindrical structure matching the inner cavity of the cavity-shaped massage part to be massaged; the sunk groove region has a sunk groove structure relative to a virtual cylinder; the virtual cylinder is a virtual cylindrical structure formed by the cylindrical region maintaining its cylindrical end face extending into the sunk groove region; the depth of the sunk groove region is M, and the M is the maximum distance from the center of the bottom surface of the sunk groove region to the tangent plane of the virtual surface region; a massage assembly having a massage element is arranged in the sunk groove region; the massage element has a degree of freedom A in the sunk groove region. The carrier can carry the massage assembly into the cavity-shaped massage part to be massaged, so as to form a massage area in the inner cavity of the cavity-shaped massage part to be massaged, ensure that the stimulation sensation is stronger, and provide effective massage for the part to be repaired; the massage assembly arranged in the sunk groove region has a larger movement amplitude, and allows the inner cavity tissue to sink into the sunk groove region to form a wrapped state with the massage element, further improving the massage stimulation sensation without generating massage pain sensation, so as to satisfy the psychological and physiological needs of users to a greater extent.

The utility model provides a seal type roller pin capable of being rotatably adjusted, which comprises a skin breaking pin and a shell with an opening on one side, a pin plate is arranged in the shell, the skin breaking pin is fixedly arranged on the pin plate, a cover plate is arranged on the opening side of the shell, and a pin hole corresponding to the skin breaking pin is arranged on the cover plate. And a handle is arranged on the shell. The seal type microneedle can be used for treating a specific skin area more accurately, and unnecessary stimulation to surrounding healthy skin is reduced. The depth of the microneedle penetrating into the skin can be adjusted more accurately, and different treatment requirements and skin conditions can be met. In the needle application process, tiny wounds can be more uniformly formed in a target area, and the consistency and stability of the treatment effect are ensured. Due to the fact that the contact area is relatively small and needle application is more concentrated, generally caused pain feelings can be relieved compared with needle rollers.