67 results about "Pain sensation" patented technology

A method and apparatus particularly useful for pain control by selectively blocking the propagation of body-generated action potentials travelling through a nerve bundle by using a tripolar electrode device to generate unidirectional action potentials to serve as collision blocks with the body-generated action potentials representing pain sensations in the small-diameter sensory fibers. In the described preferred embodiments there are a plurality of electrode devices spaced along the length of the nerve bundle which are sequentially actuated with delays corresponding to the velocity of propagation of the body-generated action potentials through the large-diameter fibers to produce a "green wave" effect which minimizes undesired anodal blocking of the large-diameter fibers while maximizing the collision blocking of the small-diameter fibers.

The present invention is a system for the non-contact stimulation of excitable tissue. A primary purpose is reducing the perception of pain in those people who suffer from persistent pain. Apparatus is described for adjusting the position of the stimulation region.

A method and apparatus for reducing chronic pain in animals by radio frequency (RF) neuromodulation of peripheral nerves of the animal is disclosed. The method, using the disclosed apparatus, comprises the steps of attaching active and dispersive percutaneous probes at respective active and dispersive locations relative to a peripheral nerve of the patient associated with the pain to be reduced; generating a first pulsed RF signal for coupling to the active and dispersive probes to verify the location of the peripheral nerve; and generating a second pulsed RF signal for coupling to the active and dispersive probes to modify propagation of pain sensation in the peripheral nerve without ablation thereof. In one embodiment of the apparatus, the active percutaneous probe includes an RF cannula having a conductive spatulate blade conformably attached to a dorsal side of a curved, blunt-ended tubular tip portion of the RF cannula. In another embodiment of the apparatus, a dispersive percutaneous probe includes a pair of 22 gauge needles connected to ground return conductors. In yet another embodiment of the apparatus, a pulsed RF generator is modified to provide specific outputs adapted to the neuromodulation of peripheral nerves in veterinary patients.

An implantable stimulation system includes a stimulation current generator encased in an implantable housing, one or more stimulation leads to deliver therapeutic stimulation from the generator to target patient tissue, and inductive elements arranged to condition the stimulation for delivery to the target tissue with increased efficiency and reduced pain sensation. The inductive elements are arranged external to the housing and integral with one or more of a stimulation lead or an external component of the housing, such as a header. The inductive elements serve to condition therapeutic stimulations such that varying the output of the generator allows the system to deliver arbitrary effective waveforms to the target tissue.

An allergy skin test device is disclosed that causes less pain than commonly used devices that include multi-point sharp puncture heads. The allergy skin test device incorporates multiple dull pressure heads distributed amongst the sharp multi-point sharp puncture heads, each dull pressure head activating a neurological pain gate that reduces pain sensation typically caused by the neighboring multi-point head when it engages the skin.

The body sensation induced potential stimulation system based on vibration includes monolithic microcomputer, pulse shaping circuit, power amplifier circuit, state display, body sensation stimulation generator, and fixer. The monolithic microcomputer calculates to synthesize pulse drive signal with specific frequency and adjustable duty ratio, so that the body sensation stimulation system generates vibration waveform with envelope simulating true touch sensation, vibration sensation and pain sensation to reach the aim of effective body sensation stimulation. The present invention controls the generation of body sensation stimulation signal simulating touch sensation, vibration sensation and pain sensation, and may be used in the application research of body sensation induced potential SEP. The present invention has the features of high integration degree, adjustable strength, high performance/cost ratio, etc. and may be widely applied.

The present invention, relates to methods including compounds, derivatives, antibodies, interfering RNA, biologies, polypeptides, dominant negative effectors, and their use in the treatment of neuropathic pain by inhibition of transient receptor potential (TRP) channels. In another embodiment, this invention relates to inhibitors, antagonists, and agonists of TRPC4. TRPC4 therapeutic agents and modulators include but are not limited to small molecule inhibitors, compounds, amino acid derivatives, polypeptides, RNA interference agents, natural chemicals, ligand derivatives, and ions. TRPC4 therapeutic agents and modulators are developed for the treatment of neuropathic pain, including but not limited to pain sensations such as nociception, hyperalgesia, allodynia, and loss of sensory function.

An electronic stimulation device for electrically stimulating at least one dorsal root ganglion with relative low pain sensations without generating relative much sensations of paresthesia comprises at least one electronic stimulation unit. The electronic stimulation unit includes at least one first electrode and at least one second electrode, and it delivers a high-frequency electrical stimulation signal to impel the first electrode and the second electrode to generate an electric field. The range of the electric field covers the dorsal root ganglion, and the electric field strength ranges from 100 V/m to 1000 V/m.

The disclosed technology can be used to enhance the brightness of a multi-wavelength light source incorporated within a dermatologic system to thereby increase its efficiency and reduce the power and filtering requirements of the system resulting in an overall reduction in the size and cost of the system. The disclosed technology can enhance a user's experience with the dermatologic system by reducing the user's pain sensation when using the system during a dermatologic treatment and/or facilitating the movement of the system across a skin surface under treatment.

The invention discloses a preparation method of a lidocaine carbonate injection. The preparation method comprises the following processes of solution preparation, pH adjustment, filtration and disinfection. The preparation method is characterized in that the filtration process comprises filtering a solution subjected to pH adjustment by a cellulose acetate microfiltration membrane having an aperture size of 0.22 micrometers, filtering the solution by a PVDF microfiltration membrane having an aperture size of 0.22 micrometers until clarification, filling the filtered solution in an ampoule, and carrying out sealing. The solution subjected to pH adjustment is filtered by the cellulose acetate microfiltration membrane having an aperture size of 0.22 micrometers, then is filtered by the PVDF microfiltration membrane, and is subjected to high-pressure steam sterilization at a high temperature of 121 DEG C so that impurities and bacteria in the solution are removed thoroughly and preparation bioavailability and absorption effects are improved. The preparation method has simple processes and is convenient for operation. The lidocaine carbonate injection obtained by the preparation method is safe and effective in clinical use and has small side-effects. Compared with the existing lidocaine carbonate injection, the lidocaine carbonate injection obtained by the preparation method obviously shortens onset time and pain sensation disappearance time and prolongs anaesthesia duration time.

The present invention discloses aseptic sticking membrane agent used for postoperation wound acesodyne, which consists of an anti-sticking layer, a drug-storing layer and a back lining layer. The drug-storing layer consists of framework material and microsphere loaded with local anesthetic, and the framework material is macromolecular polymer with film forming ability. The aseptic sticking membrane agent used for the postoperation wound acesodyne of the present invention can realize the uniform, lasting and slow release of the drug to achieve the lasting acesodyne effect, because the local anesthetic is wrapped inside the microsphere by the micro spheroidization technology. The aseptic sticking membrane agent used for the postoperation wound acesodyne of the present invention is used for the postoperation wound acesodyne, which can ensure that a patient does not have obvious painful feeling during the wound healing period.

The invention discloses a puncture needle robot for pain sensation treatment. The robot comprises a base, a lifting mechanism arranged on the base, a passive arm arranged on the lifting mechanism andan RCM mechanism arranged at the front end of the passive arm; the puncture needle robot comprises a base, a lifting mechanism arranged on the base, a passive arm arranged on the lifting mechanism andan RCM mechanism arranged at the front end of the passive arm. The passive arm includes a plurality of passive locking joints and a connecting rod arranged between the plurality of passive locking joints. The passive arm of the invention has a plurality of degrees of freedom, can increase the flexibility of the operation, and makes the operation of the complex operation simple; The passive locking joint of the invention has sufficient rigidity and locking torque, and can ensure the positioning accuracy of the front end RCM of the passive arm; The robot can give play to the advantages of stable operation and accurate positioning of the robot to ensure the operation quality. The installation angle of the passive arm and the lifting column of the invention can realize high-precision adjustment and ensure the precision and quality of the surgical treatment. The robot has the advantages of simple structure, good use effect and good application prospect.

The invention discloses a medical bed for fracture rehabilitation of children and relates to the technical field of medical treatment of the children. The medical bed comprises a bedstead, wherein twosides of the bottom of the bedstead are fixedly connected with telescopic bed legs; two sides in the bedstead are fixedly connected with slide tracks; hydraulic telescopic rods are fixedly connectedwith the positions, above the slide tracks, on two sides of the inner wall of the bedstead and fixedly connected with sliders through output rods; the bottoms of the sliders are glidingly connected with the slide tracks; the tops of the sliders are rotationally connected with support rods; the ends, away from the sliders, of the support rods are rotationally connected with a head bedstead and a foot bedstead respectively. The medical bed for fracture rehabilitation of the children achieves the purpose of automatic adjustment of bed height and guardrail position, a user adjusts the bed height conveniently, the bed is also conveniently used by a medical worker, a patient can call the medical worker in case of emergency by means of different calling modes, pain due to long-time bed rest is reduced, and bed rest comfort of the children is improved.

The invention discloses a tactile sensor for neurology department. The tactile sensor comprises a main body, wherein a top frame is fixedly connected with the top of the main body; a side wall of thetop frame is fixedly connected with a buckle hammer; the side wall of the main body is fixedly connected with a syringe; the tactile sensor relates to the technical field of medical equipment. According to the tactile sensor for the neurology department, a motor drives a rotary screw rod to do intermittent forward movement and a patient is subjected to staged acupuncture, so that a condition thatan acupuncture speed is too rapid is avoided; when the patient feels painful, the running of the device can be stopped in time, the accuracy of an examination result is improved and the aim of alleviating pains of the patient is realized; the aims that a contact needle is wiped through alcohol and disinfected in a stretching or retracting process, bacteria on the surface of the contact needle is reduced and the contact needle is convenient to use are realized; when a protection pad is in contact with skin of the patient, a pressure switch is switched on and acupuncture can be carried out; whenemergency conditions occur, the pressure of the pressure switch is reduced, the pressure switch is switched off and the motor stops moving, so that the aim of improving the safety of tactile examination of the neurology department is realized.

The invention discloses a bionic pain-free syringe needle, and belongs to the technical field of medical instruments. A needle tip, a syringe and a connector are structurally integrated, the cross section of the syringe is circular, a curve A is formed on the upper surface by a connecting line between a and b, the syringe under an overlooking angle takes a longitudinal axis c-c as a center, a sliding rail I and a sliding rail II are symmetrically arranged on two sides of the syringe under the overlooking angle, a starting point in the sliding rail I is e, a terminal point in the sliding rail Iis f, a curve B formed by a connecting line between the e and the f, a starting point in the sliding rail II is c, a terminal point in the sliding rail II is d, and a curve B' is formed by a connecting line between the c and the d. A mathematical expression of the curve A is y1=3.115*10<-5>x<3>-0.04847x<2>+27.36x-4688, wherein 350<=x<=410. The mathematical expression of the curve B is y2=5.407*10<-5>x<3>-0.07635x<2>+38.27x-6025, wherein 340<=x<=400. The bionic pain-free syringe needle simulates curve characters of a bee needle portion of a bumblebee, so that the needle of a syringe is designed and injected into the skin of a human body in a pain-free manner, and the pain of the human body can be relieved.

The invention relates to the field of medical technology, in particular to an automatic acupoint-applied directly-pressurizing micro-needle and an application method thereof. The automatic acupoint-applied directly-pressurizing micro-needle comprises a skin feeling and contact piece and an assembly housing structure. The bottom of the skin feeling and contact piece is adhered to a micro-needle positioning piece. One side, departing from the skin feeling and contact piece, of the micro-needle positioning piece is adhered to a button positioning piece. A viscous force connecting piece is arranged between the micro-needle positioning piece and the button positioning piece. One side of connection between the viscous force connecting piece and the micro-needle positioning piece is equipped witha medical adhesive tape. The middle part of the medical adhesive tape is equipped with a micro-needle structure in an adhering manner. The middle part of one side, departing the micro-needle positioning piece, of the button positioning piece is equipped with a pressure button in an embedding manner. By pressing the pressure button on the adhesive tape, a needle point vertically pierces at one time and is closely adhered and fixed by the adhesive tape. Before the needle point pierces, the skin feeling and contact piece touching the skin excites a pressure sensation nerve receptor and inhibitsa pain sensation receptor in order to relieve pains. After the adhesive tape is attached to the skin, the adhesive tape automatically separates from the micro-needle. The operation step of imbedding aneedle during treatment is simplified.

The complementary gain pain-killing medicine consists of vitamin B6, anisodamine and Tiapride. The medicine has outstand curative effect on vascular headache and excellent curative effect on the sciatica, trigeminal neuralgia and dizziness syndromes. The medicine features that it can regulate the biochemical change of vascular headache, block the conductance of pain sensation impulsion, improve microcirculation and eliminate sickness caused the prostaglandin and arachidonic acid evolution process to result in lasting pain-killing effect. The medicine has simple preparation process, is safe, non-toxic and low in cost, and may be used widely in treating vascular headache, sciatica, trigeminal neuralgia, dizziness syndromes, etc.

The invention discloses a bone marrow extraction device with a puncture point positioning function for medical bone marrow puncture. The bone marrow extraction device comprises: a base structure, wherein a rotating puncture mechanism is arranged at the upper end of the interior of the base structure; a bone marrow extraction structure which is arranged on one side of the outer wall of the rotating puncture mechanism; a bone marrow collection test tube which is arranged on one side of the outer part of the bone marrow extraction structure in a threaded manner; and a wound disinfection structure which is fixed to one side of the interior of the base structure. According to the bone marrow extraction device, the bone marrow extraction position is fixed through the binding belt, the device has the functions of disinfection, anesthesia and the like while having the puncture marrow extraction function, the two procedures of marrow extraction and anesthesia are conducted at the same time, the needle receiving frequency of a patient is reduced, the bone marrow extraction operation is more convenient, the miniature rotating tube rotating at a high speed is used for breaking and puncturing a hard human body, so that the marrow taking speed is increased, and the pain of a patient is relieved.