665 results about "Embolism" patented technology

The invention discloses a thrombus excision system. An embolus is extracted through a mechanical embolus extraction device, a blood vessel is dredged, and revascularization of the blood vessel is achieved. A saccule guide catheter is put at the near end of the embolus part when the embolus is extracted, blood flow is temporarily blocked, and thus a fine crushed embolus generated in the embolus extraction process is prevented from being flushed to the far end of the blood vessel; meanwhile, for a relatively large embolus, a part of thrombus can also be sucked by virtue of the saccule guide catheter, and then the residual thrombus can be extracted by virtue of a thrombus exsector. The thrombus exsector, the saccule guide catheter and a delivery microcatheter are arranged on the thrombus excision system disclosed by the invention, wherein the thrombus exsector is used as a main component, an excision spring is arranged, and the release state of the excision spring is a conical spiral state. Compared with the prior art, the thrombus excision system has the advantages that the thrombus exsector is very soft, the minimal through size is 0.014' (0.36mm), the thrombus exsector can easily enter a cerebral vessel, a near-end protection technology is adopted in the operation process, and thrombus suction is combined with mechanical embolus extraction, so that the success rate of the operation is improved, and the complications are reduced.

The invention provides an acute cerebral apoplexy early-stage intelligent screening and early warning method and system based on deep learning, and relates to the technical field of medical imaging and artificial intelligence, and the method comprises the steps: obtaining a multi-temporal angiography image of the brain of a patient through a pulse-type dynamic imaging scheme, extracting hemodynamic features through a double-flow feature extraction network, and obtaining a multi-temporal angiography image of the brain of the patient; and constructing a vasculopathy risk distribution diagram by combining a vascular structure analysis model, and marking a potential embolism risk area. Furthermore, in combination with tissue perfusion parameters obtained by multispectral imaging and brain tissue function parameters obtained by electroencephalogram signals, an ischemic penumbra region is identified by using a self-adaptive threshold segmentation model. And finally, based on the ischemic penumbra area, the tissue perfusion parameters and the brain tissue function parameters, calculating a risk level by using a hierarchical decision model with a space-time attention mechanism, and generating a corresponding clinical intervention scheme. According to the invention, the early accurate screening and risk early warning of acute cerebral apoplexy can be realized, and the clinical intervention efficiency is improved.

Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, positioning a distal portion of a catheter proximate to the clot material within the blood vessel. The method can further include coupling a pressure source to the catheter via a tubing subsystem including a valve or other fluid control device and, while the valve is closed, activating the pressure source to charge a vacuum. The valve can then be opened to apply the vacuum to the catheter to thereby aspirate at least a portion of the clot material from the blood vessel and into the catheter.

Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, positioning a distal portion of a catheter proximate to the clot material within the blood vessel. The method can further include coupling a pressure source to the catheter via a tubing subsystem including a valve or other fluid control device and, while the valve is closed, activating the pressure source to charge a vacuum. The valve can then be opened to apply the vacuum to the catheter to thereby aspirate at least a portion of the clot material from the blood vessel and into the catheter.

The invention discloses an embolism part for peripheral arteriovenous vessels, the embolism part comprises an anchoring part and a blocking part fixedly connected with the anchoring part, the blocking part adopts polyurethane shape memory foam, the expansion rate of the polyurethane shape memory foam is 50-100 times, and a preparation method of the polyurethane shape memory foam comprises the following steps: step 1, preparing a polyurethane shape memory foam material; the preparation method comprises the following steps: preparing a polyurethane acrylate prepolymer from macromolecular polyol, diisocyanate, a chain extender containing disulfide bonds, other micromolecular chain extenders and an acrylate end-capping reagent; and 2, uniformly mixing the polyurethane acrylate prepolymer, a foaming agent, a foaming promoter and a photoinitiator to obtain a foaming solution, and sequentially carrying out light curing and foaming on the foaming solution to obtain the polyurethane shape memory foam. According to the embolism part, the polyurethane shape memory foam is adopted as the blocking part, the blocking part applies radial acting force to the wall of the blood vessel all the time based on the expansion trend of the blocking part, and the blocking part and the anchoring part jointly act and can be stably maintained in the blood vessel.

An intra-vessel transcatheter filter device (1) designed to capture and remove emboli, thus preventing distal embolization, comprising: • a tubular filter (2) comprising a flexible porous material and defined by a distal element and a proximal element, namely a main body (3) and a funnel (4); i. said main body (3) having a length adapted to extend within a suitable vessel zone; said main body (3) comprising: a) a distal end (5) that is adapted to be radially coupled with said zone and hermetically sealed to it when the device is in an active configuration, said distal end (5) being provided of selectively actionable closure means so that said distal end is designed to be open when the device is in an active configuration and closed before the device retraction, b) a proximal end (6); ii. said funnel (4) forming an extension of said main body (3), with the funnel base located at said proximal end (6). • a support structure assembly (8) comprising: i. a supporting catheter (11) extending within said main body (3), ii. one radially expandable distal structure (9) fixed to said distal end (5), iii. one radially expandable proximal structure (10) positioned in correspondence of said proximal end (6), said distal structure (9) and said proximal structure (10) being fixed at least in an end to said supporting catheter (11).

Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions. The capture system can include a tubular body comprising a first end, a second end, and an axial length therebetween, the first end having an opening and a capture guide. The capture system can include one or more tensioners coupled to the capture guide. The tubular body has a first configuration in which the first end and the capture guide are expanded while the second end and a majority of the tubular body remains compressed. The tubular body is transformable to a second configuration by application of tension by the tensioners. The catheter can remove a large volume of clot. In some embodiments, the body of the catheter or the funnel tip is expandable. The catheter can include a dilator and a peel-away cover.

The invention belongs to the technical field of medical instruments, and particularly relates to an integrated plugging balloon suction catheter. The suction catheter comprises a woven mesh tube, the near end of the woven mesh tube is connected with a handle, and the far end opening of the woven mesh tube is used for being close to the thrombus position; the balloon is arranged on the periphery of the woven mesh tube in a sleeving mode, and the balloon is arranged at the far end of the woven mesh tube; the handle comprises a catheter suction port and a filling port, the catheter suction port is communicated with the far port of the woven mesh tube, and the filling port is communicated with the balloon. The aspiration catheter can effectively reduce the occurrence rate of thrombus escape, so that the risk of far-end embolism is reduced, and good prognosis of a patient is achieved through efficient thrombus extraction; and the extra cost of using other instruments can be reduced, so that the comprehensive cost of the operation is reduced, the thrombus extraction success rate is greatly improved, manpower and material resources are saved, and a patient is benefited.

The invention relates to the technical field of medical clinical auxiliary diagnosis, in particular to an orthopedic postoperative complication early detection and early warning system based on data analysis, which comprises a multi-modal sign synchronous acquisition module, a sign dynamic difference quantification module, a complication feature association module, a grading early warning decision module and a dissection calibration visualization module. Wherein the multi-modal sign synchronous acquisition module is used for acquiring postoperative data of a patient; calculating a difference quantization parameter; the complication characteristic association module is used for identifying associated risk characteristics of the osteofascia ventricular syndrome, the deep venous thrombosis and the fat embolism; and the grading early warning decision module is used for generating a three-level early warning instruction based on the associated risk characteristics. According to the system and the method, through a multi-modal sign synchronous acquisition, difference quantification and grading early warning linkage mechanism, accurate recognition, risk grade division and visual intervention guidance of postoperative complications are realized, and the continuity of postoperative monitoring and the timeliness of early warning are improved.

The invention discloses a thromboembolism occurrence risk assessment method and assessment system. The method comprises the following steps: acquiring a blood vessel image map of a to-be-assessed patient; inputting the blood vessel image map of the patient to be assessed into a pre-trained risk assessment model; wherein the pre-training of the risk assessment model is based on a ResNet-50 model, and self-supervised contrast learning iteration is carried out by inputting positive and negative samples so as to update model parameters; extracting a feature embedding vector in the blood vessel image; according to the feature embedding vector, calculating probability distribution of embolism occurrence risk levels through a model classification head; and according to the probability distribution, selecting a risk level label and outputting the risk level label as an evaluation result. According to the method based on the time axis symmetry, the image data of the patient is collected before and after the embolism occurrence time point, the positive and negative sample pairs are generated, the problem that the embolism sample is difficult to obtain is solved, and meanwhile the sample collection cost is reduced through self-supervised learning.

The invention belongs to the technical field of medical instruments, and discloses a stent implantation system which comprises a first catheter, a second catheter and a filter, and the first catheter can be sleeved with a stent; the second guide pipe penetrates through the first guide pipe; the filter penetrates through the second guide pipe and comprises a filter body, and the filter body has a folded state and an unfolded state; in the folding state, the filter body penetrates through the second guide pipe; in the unfolded state, the filter body is located outside the second guide pipe, and the first guide pipe can squeeze and store the unfolded filter body. According to the stent implantation system, plaque escape in the operation process is effectively prevented, and the embolism risk is reduced.

The invention discloses a venous thrombosis risk assessment method based on a large language model, and relates to the technical field of medical artificial intelligence, and the method comprises the steps: collecting thoracic surgery diagnosis and treatment data of a patient, carrying out the space-time alignment, generating a standard diagnosis and treatment data flow, and carrying out the homomorphic encryption of the standard diagnosis and treatment data flow, and forming an encrypted patient data package; inputting the encrypted patient data packet into a multi-task large language model, performing feature extraction and semantic coding by a feature coding layer, performing time sequence modeling and risk probability calculation by a risk quantification layer, and outputting a venous thromboembolism risk level of a patient; and performing feature decoupling and potential space mapping on the encrypted patient data packet to obtain thrombus semantic potential features. Through the multi-task large language model, the dual machine learning algorithm and the homomorphic encryption, the accuracy of venous thrombosis risk early warning is improved, and the safety of the risk assessment process is enhanced.

A protective umbrella and intracavity umbrella ribs are coaxially arranged on a conveying guide wire of the far-end embolism protection device, a supporting bracket of the protective umbrella is of a hollow structure, two first openings are formed in the near end of the supporting bracket and are symmetrically arranged along the central axis of the supporting bracket, and a covering film is fixed to the far end of the supporting bracket and wraps a part of the far end of the supporting bracket; a plurality of holes are formed in the covering film, the intracavitary umbrella ribs are located in the supporting support and are of a hollow structure, and second openings of the intracavitary umbrella ribs face the far end of the supporting support. The intracavity umbrella ribs and the covering film form a double-layer filtering structure, so that the situation that thrombus clots are accumulated in the inner cavity of the protection umbrella is effectively improved, the probability that meshes / micropores of the protection umbrella are blocked is reduced, and sufficient blood supply of a nervous system is ensured; the intracavitary umbrella ribs and the supporting bracket are coaxially arranged, so that the stability of the protective umbrella in the blood vessel is improved, the protective umbrella is not prone to inclination, and effective capture of free thrombus is ensured; the arrangement of the two first openings ensures that an effective capture channel can be provided even in an inclined condition.

Devices, systems, and methods for sealing medical devices, particularly during intravascular access, are disclosed herein. Some aspects relate to a hemostatic valve for sealing a wide range of medical devices, such as catheters, wires, embolectomy systems. The valve can include an elongate member having a first end, a second end, and a central lumen extending therebetween. A reinforcement structure extends along at least a portion of the elongate member and is coupled to the elongate member. A shell defining a first aperture and a second aperture may be included, which first and second apertures can be fluidly coupled by the elongate member. A tensioning mechanism is coupled to the shell and to the elongate member, the tensioning mechanism can be moveable between a first configuration wherein the tensioning mechanism is collapsed and the central lumen is sealed and a second configuration wherein the central lumen is open.

The invention relates to an embolism microcatheter with a detachable head end and a method, and belongs to the technical field of cerebrovascular malformation surgical instruments. The embolism micro-catheter with the outer tube, the inner tube and the weak blocking part is arranged to serve as a catheter appliance for the cerebral vascular deformity operation, fluid is injected into the bypass tube of the outer tube to break the weak blocking part so as to achieve disengagement and separation of the embolism micro-catheter, and therefore the situation that the micro-catheter adheres to the cerebral vessels can be avoided; meanwhile, the microcatheter can be effectively released, the releasing condition can be observed through an instrument of the pressure pump, the efficiency of the cerebrovascular malformation operation is improved, and the operation cost is reduced.

The present invention provides an early intelligent screening and warning method and system for acute stroke based on deep learning, which relates to the field of medical imaging and artificial intelligence technology, including obtaining multi-phase angiography images of the patient's brain through a pulsed dynamic imaging scheme, extracting hemodynamic characteristics using a dual-stream feature extraction network, and constructing a vascular lesion risk distribution map in combination with a vascular structure analysis model to mark potential embolism risk areas. Further, combining tissue perfusion parameters obtained by multispectral imaging and brain tissue function parameters obtained by electroencephalogram signals, an adaptive threshold segmentation model is used to identify the ischemic penumbra area. Finally, based on the ischemic penumbra area, tissue perfusion parameters, and brain tissue function parameters, a hierarchical decision model with a spatiotemporal attention mechanism is used to calculate the risk level and generate a corresponding clinical intervention plan. The present invention can achieve early and accurate screening and risk warning of acute stroke, and improve the efficiency of clinical intervention.

The invention discloses a colorectal cancer postoperative venous thromboembolism risk prediction method and system, and the method comprises the steps: obtaining clinical pathology data of a historical patient before the patient receives a total proctectomy, carrying out the preprocessing of the clinical pathology data, employing a standardized score to detect an abnormal value in the clinical pathology data, carrying out the filling of a missing value, and carrying out the prediction of the risk of the venous thromboembolism. Performing standardization processing on the continuous variables; based on the preprocessed clinical pathology data, extracting clinical pathology features by adopting Lasso regression and grid search; constructing a Stacking integration model based on a random forest, a CatBoost model and logistic regression, and training the Stacking integration model by using the extracted clinical pathological features; and by using the trained Stacking integrated model, processing clinical pathology data of a target patient before the target patient receives the total proctectomy to obtain a prediction result. The colorectal cancer postoperative venous thromboembolism risk can be effectively predicted, and support is provided for clinical decision making.

The invention relates to an aneurysm embolism device, comprising: a connecting wire comprising a flexible section, an embolism section and a shaping section; the flexible section is located at the end, close to the far end, of the connecting wire, the shaping section is located at the end, close to the near end, of the connecting wire, and the embolism section is located between the flexible section and the shaping section. The connecting wire is made of a nickel-titanium alloy material; the guide spring is arranged on the flexible section in a sleeving manner and is connected with the connecting wire; the end, close to the far end, of the guide spring is a hemispherical end. The developing wire is wound on the plug section; the plurality of fiber pieces are arranged on the developing wire and are sequentially arranged at intervals along the length direction of the connecting wire; the closed spring is arranged on the shaping section in a sleeving manner; the first limiting ball is arranged on the shaping section of the connecting wire and located at the end, close to the near end, of the closed spring. The structure occupies a small space in the lumen of the micro-catheter in a compressed state, and even if a fiber piece is arranged on the developing wire, the aneurysm embolization device can still be transported in the micro-catheter conveniently. The invention also relates to a conveying system.

The present disclosure relates to devices and methods for removing emboli from one or more blood vessels. In an example, an embolus removal apparatus includes a delivery catheter, an embolus collection basket connected to a basket shaft extending through the delivery catheter, a retrieval shaft extending through the delivery catheter, and at least one capture mechanism configured to couple an embolus to a distal portion of the retrieval shaft. The retrieval shaft is can be navigated, with the embolus carried thereby, toward and into a cavity of the basket, and can optionally release the embolus in the basket and optionally be navigated to capture and direct another embolus, if required, to the basket. Once all emboli are collected in the basket's cavity, the apparatus can be retrieved from the patient's body with the emboli captured therein.

A prosthetic aortic valve that uses actuating arms and grippers to attach to leaflets, reducing device migration and sizing issues. It involves excising diseased leaflets prior to implantation, ensuring blood flow to coronary arteries, and offers optical visualization. The valve features replaceable leaflets and a streamlined frame. Innovative left atrial appendage devices, embolic protection devices, intra-cardiac echocardiography devices, and steerable catheter devices are introduced. Provided herein are atraumatic, cinchable mitral valve annular repair devices, noninvasive methods that modify body calcium with electromagnetic energy, and systems for optical visualization in vascular interventions by displacing blood with clear fluid.

Devices, systems, and methods for sealing medical devices, particularly during intravascular access, are disclosed herein. Some aspects relate to a hemostatic valve for sealing a wide range of medical devices, such as catheters, wires, embolectomy systems. The valve can include an elongate member having a first end, a second end, and a central lumen extending therebetween. A reinforcement structure extends along at least a portion of the elongate member and is coupled to the elongate member. A shell defining a first aperture and a second aperture may be included, which first and second apertures can be fluidly coupled by the elongate member. A tensioning mechanism is coupled to the shell and to the elongate member, the tensioning mechanism can be moveable between a first configuration wherein the tensioning mechanism is collapsed and the central lumen is sealed and a second configuration wherein the central lumen is open.

The invention provides a double-layer embolism protection device and an embolism protection system.The double-layer embolism protection device comprises a wall-attached support, a conveying guide wire, a first intercepting filter screen and a second intercepting filter screen, and the wall-attached support is provided with a deformable containing space; the conveying guide wire is arranged in the wall-attached support in a penetrating mode, and the wall-attached support is connected with the conveying guide wire. First filter holes are formed in the first intercepting filter screen, the first intercepting filter screen is arranged around the conveying guide wire, the near end of the first intercepting filter screen is connected to the far end of the wall-attached support, and the far end of the first intercepting filter screen is slidably connected to the conveying guide wire; second filter holes are formed in the second intercepting filter screen, the second intercepting filter screen is arranged around the conveying guide wire and arranged on the outer side of the first intercepting filter screen in a sleeving mode, the near end of the second intercepting filter screen is connected to the far end of the wall-attached support, and the far end of the second intercepting filter screen is connected to the conveying guide wire in a sliding mode. The thrombus or plaque filtering device can effectively filter thrombus or plaque and prevent thrombus or plaque from flowing to the downstream of the blood vessel.

The invention discloses a screw feeding device which is suitable for a pedicle screw. The screw feeding device comprises an implanting mechanism and a torque applying mechanism which are in transmission connection with a pedicle screw; the torque applying mechanism is configured to be in an engaged state and a disengaged state with the implanting mechanism; when the torque applying mechanism and the implantation mechanism are in a joint state, the torque applying mechanism can transmit torque to the implantation mechanism; and when the torque applying mechanism and the implanting mechanism are in a separated state, the torque applying mechanism is separated from the implanting mechanism, so that the torque is prevented from acting on the implanting mechanism in the exiting process of the torque applying mechanism, and the pedicle screw is prevented from loosening. According to the vertebral pedicle screw, the operation time can be shortened, the operation steps can be simplified, the cooperation among instruments can be optimized, the complex operation of a surgeon on the cooperation of the instruments can be reduced, the vertebral pedicle screw cannot be loosened, and bone cement can be rapidly placed at the same time, so that the possibility of bone cement leakage and embolism can be reduced.

The invention relates to the field of medical information technology and medical data analysis, in particular to a VTE risk prediction method and system based on multi-modal data fusion and dynamic risk modeling, and the system comprises a first feature extraction module, a second feature extraction module, a two-stage risk assessment module and a final risk judgment module. According to the application, through integration of clinical diagnosis and treatment, iconography and genomics data, a deep learning algorithm, a dynamic weight adjustment mechanism and a graph neural network technology are utilized to realize accurate prediction of the VTE risk of the active-stage lung cancer patient. And meanwhile, the problem of cross-mechanism data distribution difference is solved by adopting transfer learning, and the generalization ability of the model is improved. The method can significantly improve the prediction accuracy, reduces the manual intervention demands, and optimizes the medical resource distribution efficiency.

Systems and methods are adapted for treating the carotid artery. The systems include interventional catheters and blood vessel access devices that are adapted for transcervical insertion into the carotid artery. Embodiments of the systems and methods can be used in combination with embolic protection systems including blood flow reversal mechanisms, arterial filters, and arterial occlusion devices.

Method and systems for closing an opening formed during a medical procedure are disclosed. An example method may include advancing a needle through patient tissue to form an opening into a bile duct region, performing an intervention within the bile duct region, and advancing an embolic gel into the opening to close the opening.

The invention discloses a coronary artery thrombectomy device and a use method thereof. The invention relates to an embolectomy device comprising an embolectomy head which is particularly designed to be deployable in a complex coronary artery system in order to optimally treat coronary artery diseases. The thrombector head may include a deployable framework having a plurality of branches that are in a closed state in a first position and an expanded state in a second position from which the framework expands radially away from the longitudinal axis, thereby enabling mechanical opening of an intravascular embolism pathway, and the operation can be repeated for multiple times in the folded state and the expanded state. The framework may include a capture protection net surrounding a distal end of the framework for capturing thrombus and fragments thereof. The thrombectomy device can be used for working in a straight and bent vascular system. In the thrombus removal process, the head of the thrombus extraction device can be inserted into the thrombus by using a proper guide wire; and then framework expansion is carried out to take out thrombus.

A prosthetic heart valve delivery catheter includes an embolic filter to provide integrated embolic protection to inhibit the release of emboli into the aorta, the aortic arch or branch vessels, and other vasculature during transvascular heart valve replacement procedures. The embolic filter will usually be fixedly or movably attached to a shaft of the delivery catheter proximal of the prosthetic heart valve.

Devices, systems and methods for filtering embolic particles that may be generated from a medical procedure including protection of the major branching vessels from the aorta, and catches and filters emboli that may be generated during the TAVR procedure. The filter devices disclosed herein form an improved seal against the vessel wall that is activated by flowing blood. Devices described herein also allow for the closing of the ends of the filter device after capture of emboli, providing further security against accidental loss of emboli post capture.

Systems and methods for implanting a shunt for regulating blood pressure between a patient's left and right atria are provided. The shunt comprises an anchor having a neck region, first and second end regions, and a conduit affixed with the anchor formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism. The shunt may be advanced through the sheath until the first region protrudes from the sheath and self-expands within the left atrium. The shunt and the sheath may then be retracted until the first region contacts the left side of the atrial septum. The sheath may further be retracted until the counterforce exerted by shunt tension on the atrial septum overcomes the friction of the retained portions of the shunt such that the second region is exposed from the sheath and self-expands within the second atrium.