330 results about "Embolism" patented technology

The invention discloses a thrombus excision system. An embolus is extracted through a mechanical embolus extraction device, a blood vessel is dredged, and revascularization of the blood vessel is achieved. A saccule guide catheter is put at the near end of the embolus part when the embolus is extracted, blood flow is temporarily blocked, and thus a fine crushed embolus generated in the embolus extraction process is prevented from being flushed to the far end of the blood vessel; meanwhile, for a relatively large embolus, a part of thrombus can also be sucked by virtue of the saccule guide catheter, and then the residual thrombus can be extracted by virtue of a thrombus exsector. The thrombus exsector, the saccule guide catheter and a delivery microcatheter are arranged on the thrombus excision system disclosed by the invention, wherein the thrombus exsector is used as a main component, an excision spring is arranged, and the release state of the excision spring is a conical spiral state. Compared with the prior art, the thrombus excision system has the advantages that the thrombus exsector is very soft, the minimal through size is 0.014' (0.36mm), the thrombus exsector can easily enter a cerebral vessel, a near-end protection technology is adopted in the operation process, and thrombus suction is combined with mechanical embolus extraction, so that the success rate of the operation is improved, and the complications are reduced.

The invention discloses an embolism part for peripheral arteriovenous vessels, the embolism part comprises an anchoring part and a blocking part fixedly connected with the anchoring part, the blocking part adopts polyurethane shape memory foam, the expansion rate of the polyurethane shape memory foam is 50-100 times, and a preparation method of the polyurethane shape memory foam comprises the following steps: step 1, preparing a polyurethane shape memory foam material; the preparation method comprises the following steps: preparing a polyurethane acrylate prepolymer from macromolecular polyol, diisocyanate, a chain extender containing disulfide bonds, other micromolecular chain extenders and an acrylate end-capping reagent; and 2, uniformly mixing the polyurethane acrylate prepolymer, a foaming agent, a foaming promoter and a photoinitiator to obtain a foaming solution, and sequentially carrying out light curing and foaming on the foaming solution to obtain the polyurethane shape memory foam. According to the embolism part, the polyurethane shape memory foam is adopted as the blocking part, the blocking part applies radial acting force to the wall of the blood vessel all the time based on the expansion trend of the blocking part, and the blocking part and the anchoring part jointly act and can be stably maintained in the blood vessel.

An intra-vessel transcatheter filter device (1) designed to capture and remove emboli, thus preventing distal embolization, comprising: • a tubular filter (2) comprising a flexible porous material and defined by a distal element and a proximal element, namely a main body (3) and a funnel (4); i. said main body (3) having a length adapted to extend within a suitable vessel zone; said main body (3) comprising: a) a distal end (5) that is adapted to be radially coupled with said zone and hermetically sealed to it when the device is in an active configuration, said distal end (5) being provided of selectively actionable closure means so that said distal end is designed to be open when the device is in an active configuration and closed before the device retraction, b) a proximal end (6); ii. said funnel (4) forming an extension of said main body (3), with the funnel base located at said proximal end (6). • a support structure assembly (8) comprising: i. a supporting catheter (11) extending within said main body (3), ii. one radially expandable distal structure (9) fixed to said distal end (5), iii. one radially expandable proximal structure (10) positioned in correspondence of said proximal end (6), said distal structure (9) and said proximal structure (10) being fixed at least in an end to said supporting catheter (11).

The invention belongs to the technical field of medical instruments, and particularly relates to an integrated plugging balloon suction catheter. The suction catheter comprises a woven mesh tube, the near end of the woven mesh tube is connected with a handle, and the far end opening of the woven mesh tube is used for being close to the thrombus position; the balloon is arranged on the periphery of the woven mesh tube in a sleeving mode, and the balloon is arranged at the far end of the woven mesh tube; the handle comprises a catheter suction port and a filling port, the catheter suction port is communicated with the far port of the woven mesh tube, and the filling port is communicated with the balloon. The aspiration catheter can effectively reduce the occurrence rate of thrombus escape, so that the risk of far-end embolism is reduced, and good prognosis of a patient is achieved through efficient thrombus extraction; and the extra cost of using other instruments can be reduced, so that the comprehensive cost of the operation is reduced, the thrombus extraction success rate is greatly improved, manpower and material resources are saved, and a patient is benefited.

The invention discloses a venous thrombosis risk assessment method based on a large language model, and relates to the technical field of medical artificial intelligence, and the method comprises the steps: collecting thoracic surgery diagnosis and treatment data of a patient, carrying out the space-time alignment, generating a standard diagnosis and treatment data flow, and carrying out the homomorphic encryption of the standard diagnosis and treatment data flow, and forming an encrypted patient data package; inputting the encrypted patient data packet into a multi-task large language model, performing feature extraction and semantic coding by a feature coding layer, performing time sequence modeling and risk probability calculation by a risk quantification layer, and outputting a venous thromboembolism risk level of a patient; and performing feature decoupling and potential space mapping on the encrypted patient data packet to obtain thrombus semantic potential features. Through the multi-task large language model, the dual machine learning algorithm and the homomorphic encryption, the accuracy of venous thrombosis risk early warning is improved, and the safety of the risk assessment process is enhanced.

Devices, systems, and methods for sealing medical devices, particularly during intravascular access, are disclosed herein. Some aspects relate to a hemostatic valve for sealing a wide range of medical devices, such as catheters, wires, embolectomy systems. The valve can include an elongate member having a first end, a second end, and a central lumen extending therebetween. A reinforcement structure extends along at least a portion of the elongate member and is coupled to the elongate member. A shell defining a first aperture and a second aperture may be included, which first and second apertures can be fluidly coupled by the elongate member. A tensioning mechanism is coupled to the shell and to the elongate member, the tensioning mechanism can be moveable between a first configuration wherein the tensioning mechanism is collapsed and the central lumen is sealed and a second configuration wherein the central lumen is open.

Devices, systems, and methods for sealing medical devices, particularly during intravascular access, are disclosed herein. Some aspects relate to a hemostatic valve for sealing a wide range of medical devices, such as catheters, wires, embolectomy systems. The valve can include an elongate member having a first end, a second end, and a central lumen extending therebetween. A reinforcement structure extends along at least a portion of the elongate member and is coupled to the elongate member. A shell defining a first aperture and a second aperture may be included, which first and second apertures can be fluidly coupled by the elongate member. A tensioning mechanism is coupled to the shell and to the elongate member, the tensioning mechanism can be moveable between a first configuration wherein the tensioning mechanism is collapsed and the central lumen is sealed and a second configuration wherein the central lumen is open.

The invention discloses a screw feeding device which is suitable for a pedicle screw. The screw feeding device comprises an implanting mechanism and a torque applying mechanism which are in transmission connection with a pedicle screw; the torque applying mechanism is configured to be in an engaged state and a disengaged state with the implanting mechanism; when the torque applying mechanism and the implantation mechanism are in a joint state, the torque applying mechanism can transmit torque to the implantation mechanism; and when the torque applying mechanism and the implanting mechanism are in a separated state, the torque applying mechanism is separated from the implanting mechanism, so that the torque is prevented from acting on the implanting mechanism in the exiting process of the torque applying mechanism, and the pedicle screw is prevented from loosening. According to the vertebral pedicle screw, the operation time can be shortened, the operation steps can be simplified, the cooperation among instruments can be optimized, the complex operation of a surgeon on the cooperation of the instruments can be reduced, the vertebral pedicle screw cannot be loosened, and bone cement can be rapidly placed at the same time, so that the possibility of bone cement leakage and embolism can be reduced.

The invention relates to the field of medical information technology and medical data analysis, in particular to a VTE risk prediction method and system based on multi-modal data fusion and dynamic risk modeling, and the system comprises a first feature extraction module, a second feature extraction module, a two-stage risk assessment module and a final risk judgment module. According to the application, through integration of clinical diagnosis and treatment, iconography and genomics data, a deep learning algorithm, a dynamic weight adjustment mechanism and a graph neural network technology are utilized to realize accurate prediction of the VTE risk of the active-stage lung cancer patient. And meanwhile, the problem of cross-mechanism data distribution difference is solved by adopting transfer learning, and the generalization ability of the model is improved. The method can significantly improve the prediction accuracy, reduces the manual intervention demands, and optimizes the medical resource distribution efficiency.

Systems and methods for implanting a shunt for regulating blood pressure between a patient's left and right atria are provided. The shunt comprises an anchor having a neck region, first and second end regions, and a conduit affixed with the anchor formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism. The shunt may be advanced through the sheath until the first region protrudes from the sheath and self-expands within the left atrium. The shunt and the sheath may then be retracted until the first region contacts the left side of the atrial septum. The sheath may further be retracted until the counterforce exerted by shunt tension on the atrial septum overcomes the friction of the retained portions of the shunt such that the second region is exposed from the sheath and self-expands within the second atrium.

The invention relates to the technical field of control of intelligent implanted medical instruments, and discloses an aneurysm neck sealing system and a control method. Digital subtraction angiography is adopted to measure the neck diameter in multiple directions, an average value is calculated, the target neck sealing radius is set by combining the size of an embolism device, and it is ensured that instrument type selection is scientific and reasonable. The triggering temperature and recovery kinetics of the shape memory polymer are determined through a constant-temperature experiment, an actual expansion radius model is established, and quantitative control over the heating process is ensured. A heat balance model is established by using the heat capacity and cooling curve of the embolism device, and temperature rise and heating power expressions are deduced, so that fine regulation and control of temperature and power are realized. And natural cooling is performed after heating to a set terminal point, the plugging effect is evaluated in real time through iconography measurement, and compensation heating or model replacement is performed according to actual differences to ensure the plugging effect.

The invention relates to an extracorporeal circulation control method based on membrane lung resistance and an extracorporeal membrane lung oxygenation system thereof, and aims to solve the core technical bottlenecks of membrane lung blockage, efficiency reduction, embolism risk increase and operation time limitation caused by coagulation activation and thrombosis due to the fact that blood is in contact with non-biological materials in an ECMO system. The core is that pressure sensors at three key positions are used for monitoring an outlet and an inlet of the magnetic suspension blood pump and a membrane lung outlet in real time. And calculating membrane lung resistance pressure difference and scouring resistance pressure difference on the basis. And the system continuously judges whether the pressure difference is abnormal or not. When the pressure difference is normal, the constant flow mode of the blood pump is maintained, and the operation efficiency and stability are guaranteed. And once it is detected that the membrane lung resistance pressure difference and / or the flushing resistance pressure difference are / is abnormal, the blood pump is immediately switched to the pulsation mode. On one hand, thrombus which is deposited or loosened on membrane lung fibers can be physically scoured and scattered, and the blocking process is delayed; on the other hand, the risk that large free thrombus forms embolism can be remarkably reduced.

The invention relates to perfusion pump equipment applied to intra-articular flushing and a control method. The method comprises the steps that a liquid injection pump is driven by a liquid injection pump driving circuit to inject medical flushing liquid into an operation cavity; a pressure sensor is used for collecting real-time expansion pressure in the liquid injection process of the liquid injection pump; the difference value between the real-time expansion pressure and the set expansion pressure is calculated; calculating control parameters of the liquid injection pump by combining the difference value, the historical accumulated difference value and the difference value change trend; based on the control parameters, the flow speed of the liquid injection pump injected into the surgical cavity is adjusted through the liquid injection pump driving circuit. By dynamically regulating and controlling the liquid injection pump, the expansion pressure is kept stable, the problem of pressure fluctuation caused by intermittent liquid injection in the prior art is avoided, the surgical space and the surgical field definition can be effectively maintained, and the risk that air enters an articular cavity and causes embolism is reduced.

The utility model discloses a splenic artery blood flow limiting support, and particularly relates to the technical field of medical instruments, the splenic artery blood flow limiting support comprises a supporting support and a flow limiting support, the supporting support is sleeved outside the flow limiting support, two ends of the flow limiting support are fixedly connected with the inner side wall of the supporting support, the flow limiting support is a covered stent, and the flow limiting support comprises a contraction section and an expansion section. The contraction section and the expansion section are fixedly connected and communicated, and splenic artery blood flow in the supporting stent flows in from the contraction section and flows out from the expansion section. The splenic artery embolism postoperative spleen blood perfusion can be reduced, and the recurrence of splenic hyperfunction is reduced.

The invention relates to the technical field of intelligent medical treatment and accurate risk management of obstetrics, in particular to a dynamic risk assessment system and method for venous thromboembolism of pregnant and lying-in women based on multi-modal data fusion. The system is composed of a multi-modal data acquisition module, a cloud data processing module and an early warning feedback module. The multi-modal data acquisition module is integrated with the micro-fluidic chip to rapidly detect blood coagulation markers, the genetic information analysis unit is used for screening gene mutation, and the intelligent pressure socks are used for monitoring hemodynamic parameters in real time; the cloud data processing module adopts a long-short-term memory network model, inputs dynamic feature sequences of continuous 30 days, and outputs VTE risk level probabilities in the future 7 days; the early warning feedback module pushes a grading intervention scheme; dynamic monitoring is implemented in early, middle and late pregnancy stages and postpartum stages, and dynamic risk updating is realized in combination with clinical rules and deep learning. Clinical tests show that the sensitivity, the specificity and the early warning timeliness of the system are remarkably improved, and the ICU transfer-in rate is reduced.

A computer-implemented method of predicting a status of an embolization procedure on an aneurism, includes: receiving (S110) projection image data (110) representing temporal blood flow in a region of the anatomy including the aneurism during the embolization procedure; inputting (S120) the received projection image data (110) into a neural network (120) trained to predict temporal blood flow (130), wherein the neural network (120) is trained to predict temporal blood flow (130) using training data (140) representing temporal blood flow in a region of the anatomy that does not include an aneurism; and in response to the inputting (S120): generating (S130) an output (160) indicative of the status of the embolization procedure based on the predicted temporal blood flow.

The embodiment of the invention provides an expansion catheter device. The dilation catheter device comprises a catheter body assembly and a balloon body assembly. The pipe body assembly comprises a first pipe body and a second pipe body which extend in the same axial direction and can move relative to the axial direction. The second pipe body penetrates through the first pipe body. The balloon body assembly comprises an expansion balloon body and an interception balloon body which are arranged at the far end of the second tube body at an interval; the expansion bag body and the interception bag body are arranged in an expandable or contractible mode. Wherein the expansion bag body and the interception bag body are used for inputting filler to expand when the bag body assembly is exposed out of the first tube body along with relative axial movement, and a thrombus interception space is defined by the expansion bag body and the interception bag body and the blood vessel wall, so that at least part of thrombus extruded by the expansion bag body enters the thrombus interception space; and the first tube body enters the thrombus interception space to perform thrombus suction action. The expanded intercepting capsule body can intercept part of thrombus which falls off due to extrusion, and the thrombus is prevented from flowing to the far end of a blood vessel and causing embolism; and the first tube body can also suck the intercepted part of thrombus out of the body.

A catheter device is disclosed comprising; an elongate sheath (503) with a lumen and a distal end for positioning at a heart valve (6), an embolic protection device (200) for temporarily positioning in the aortic arch for deflection of embolic debris from the ascending aorta to the descending aorta, said embolic protection device is connectable to a transluminal delivery unit (130) extending proximally from a connection point (131), and having: a frame with a periphery, a blood permeable unit within said periphery for preventing embolic particles from passing therethrough with a blood flow downstream an aortic valve into side vessels of said aortic arch to the brain of a patient, and at least one tissue apposition sustaining unit (300, 350) extending from said catheter, into said aortic arch, and being attached to said embolic protection device at a sustaining point (502), for application of a stabilization force offset to said connection point at said embolic protection device, such as at said periphery, and for providing said stabilization force towards an inner wall of said aortic arch, away from said heart, and in a direction perpendicular to a longitudinal extension of said periphery, when said catheter device is positioned in said aortic arch, such that tissue apposition of said periphery to an inner wall of said aortic arch is supported by said force for improving stability and peripheral sealing. In addition related methods are disclosed.

A method of providing embolic protection for carotid stent implantation includes advancing an arterial sheath into an arterial system of a patient and advancing a venous sheath into a venous system of the patient. A fluid connection may be established between the venous sheath and the arterial sheath to enable retrograde flow of blood through the arterial sheath. The artery sheath may be advanced through the vasculature into the patient's carotid artery and the inflatable balloon may be inflated within the patient's carotid artery to block smooth blood flow therein. An interventional tool may be advanced through the interior lumen of the arterial sheath, the interventional tool sized such that a portion of the cross-sectional area of the interior lumen of the arterial sheath remains open for retrograde flow of blood.

A system for transvascular delivery to an aortic arch of a patient includes an embolic protection device, a connector mechanism, and a catheter or sheath for delivering the embolic protection device to a working zone. The embolic protection device includes a support frame having a distal portion and a proximal portion, and a filter member attached to the support frame and configured for preventing embolic materials from passing there through. At least one of the distal portion and the proximal portion includes a spring section configured for providing a radial force between the support frame and a wall of the aortic arch when in an expanded state. The embolic protection device is pivotable axially but not radially relative to the connector mechanism.

The thrombus aspiration catheter comprises a catheter body and a deformation structure, and the deformation structure comprises a plurality of supporting rings and deformation assemblies arranged between every two adjacent supporting rings; when the axial distance between every two adjacent supporting rings is reduced, the deformation assembly deforms inwards in the radial direction, and the deformation assembly and the two adjacent supporting rings jointly form a variable-diameter channel with the inner diameter firstly decreasing and then increasing from far to near. When the axial distance between every two adjacent supporting rings is increased, the deformation assemblies deform and recover in the radial direction, and the minimum inner diameter of a channel formed by the deformation assemblies and the two adjacent supporting rings is correspondingly increased. The variable-diameter channel can form mechanical wrapping and clamping on the thrombus at the position with the minimum inner diameter, and thrombus escape or far-end embolism in the suction process is effectively prevented; meanwhile, the structure is beneficial for forming a negative pressure enhancing cavity at the far end of the catheter body, and stable grasping and concentrated efficient suction of the thrombus are achieved.

Provided are methods of contraception using as a first line combined oral contraceptive (COC), a COC composition comprising nomegestrol acetate (NOMAC) and estradiol or an ester thereof. Said COC compositions are associated with a lower risk of venous thromboembolism (VTE) as compared to other CHCs. The compositions may also be used in methods of treatment in women having conditions linked to menstruation and / or fertility.

The application provides a long-acting, non-embolism filling monodisperse chitosan microsphere, the base material of the microsphere is cross-linked chitosan, the cross-linked chitosan is formed by cross-linking reaction of component A and a cross-linking agent, or formed by cross-linking reaction of component A, component B and the cross-linking agent; the component A is at least one of chitosan and modified chitosan, and the component B is at least one of hyaluronic acid, collagen and gelatin; the particle size of the microsphere is 20-120 mu m, and the variation coefficient of the microsphere particle size is not more than 5%. The application also provides a preparation method of the microsphere. The monodispersity of the microsphere is excellent, the degradation time is relatively longer, the water absorption performance is good, the embolism risk can be reduced, the filling effect maintaining time can be prolonged, and the effect of improving wrinkles can be increased, and the problems of short filling effect maintaining time and easy to cause blood vessel embolism of the filling hyaluronic acid product used in the existing medical and beauty field can be solved.

The utility model belongs to the technical field of medical tools, and particularly relates to a lower limb vein embolism prevention device which comprises a bed body, a mattress is arranged on the top of the bed body, a massage assembly is connected to the inner side of the mattress in an inserted mode, the massage assembly comprises an outer frame, an electric hydraulic cylinder and a moving frame, and a moving hole is formed in the top of the outer frame. A soft cushion is fixed to the inner side of the moving hole, and a massage ball is fixed to the middle of the soft cushion. After a patient lies on the mattress, the lower limbs of the patient are placed above the mattress and above the massage balls, the electric hydraulic cylinder is started through an external power source to drive the movable frame to move in a reciprocating mode, and therefore the extrusion columns can extrude the massage balls in a reciprocating mode and jack the massage balls upwards, and massage operation on the lower limbs of the patient is achieved. Meanwhile, the massage assembly is hidden below the mattress, the situation that the space of the bed surface is occupied is avoided, medical staff can conveniently conduct nursing operation such as examination or cleaning on the patient, and practicability is high.

The application discloses a peripheral blood vessel intervention thrombus-removing catheter with a distal embolism protection structure and relates to the technical field of blood vessel thrombus-removing catheters.The peripheral blood vessel intervention thrombus-removing catheter with the distal embolism protection structure comprises a catheter body, one end of the catheter body is provided with a thrombus-removing assembly, the surface of the catheter body is provided with a thrombus-removing assembly, the inside of the catheter body is provided with a transmission assembly, the thrombus-removing assembly comprises a protection pipe network fixedly installed on one side of the catheter body.The transmission assembly is arranged, in the process of use, the rotation of a lead screw can drive one end of the lead screw to move the one side of the filter screen plate to the inside of the protection pipe network, so that the protection pipe network is expanded, and the air bag piece can be inflated, the catheter is placed into in the process of use, the preparation time of catheter operation is reduced, the catheter is convenient to operate, the thrombus-removing and protection operation of the catheter are improved, and the use convenience of the catheter is improved.

The invention provides an in-aorta balloon catheter with a thrombus prevention function, and belongs to the technical field of aorta balloon counterpulsation. Comprising an expandable balloon, a first outer catheter is arranged in the center of the interior of the balloon, a thrombus filtering part is arranged at the end, away from the balloon, of the first outer catheter, a third outer catheter is arranged at the other end of the thrombus filtering part, and a connecting part which is arranged outside a body and used for allowing the balloon to be shrunken and inflated and allowing a guide wire to penetrate is arranged on the other side of the third outer catheter. By opening the thrombus filtering part and the filtering umbrella net, small thrombus fragments which are crushed and fall off by the balloon can be filtered and collected in the filtering umbrella net, so that the thrombus fragments are effectively prevented from flowing along with blood, and the small thrombus fragments which are accumulated between the closed filtering umbrella net and the outer catheter II are moved out of a human body along with the outer catheter I and the thrombus filtering part; the fallen small-fragment thrombus can be well removed from the human body, the risk that the small-fragment thrombus flows to the minimum end of a blood vessel along with blood flow to cause embolism is effectively reduced, and the using effect is greatly improved.

An embolic protection system for delivering, deploying, and retrieving a filter configured to capture particles that may become dislodged during a medical procedure. The embolic protection system may include an embolic protection device that captures the particles, a delivery catheter assembly for delivering the embolic protection device to a target location within the vasculature, and a retrieval catheter assembly for retrieving the embolic protection device, along with the captured particles, from the target location after use. The embolic protection device includes a filter movably connected to a guidewire, such that after deployment, the filter can move both axially and rotationally relative to the guidewire, thereby reducing the risk of vasospasm or vascular dissection.

The invention discloses a prediction model system for multiple myeloma venous thromboembolism, and the system comprises a data obtaining module which obtains detection data including baseline data; the data category imbalance processing module is used for performing category imbalance processing according to the baseline data to obtain sample data; the data variable screening processing module is used for carrying out variable screening according to the sample data to obtain characteristic variable data; and the data visualization processing module is used for determining the weight of each variable based on proportional risk regression according to the characteristic variable data, incorporating the weight into a preliminary screening variable, segmenting continuous variables, establishing a point value conversion system, calculating a total score and corresponding to a risk probability, and constructing a data visualization chart. The invention discloses a prediction model system for multiple myeloma venous thromboembolism, a storage medium and a use method, and aims to greatly improve the cross-metal transmission rate of ultrasonic signals and improve the accuracy, stability, convenience and practicability of risk early warning.

Tubular braided implantable endovascular embolization device including a folded over tubular braid forming a folded over atraumatic distal surface and preformed into multiple distinct sections including: a stabilizing section; a sealing section; an intermediate section interposed between the sealing and stabilizing sections; and a proximal section. The stabilizing section and the sealing section are radially self-expanding to a maximum outer diameter larger than the intermediate section or the proximal section. Enhanced stiffness while obstructing open space regions maximizing disruption of blood flow therethrough is achieved by using a plurality of nested layers (at least one of which is the folded over tubular braid) to form the sealing section while the stabilizing section preferably formed by a single braided layer (i.e., the folded over tubular braid) optimizes compressibility and positioning.

An endovascular embolization system including a braided implantable device having: a tubular braid pre-formed as a default shape into multiple distinct sections including: an intermediate section interposed directly between a stabilizing section and a sealing section; the intermediate section having a stiffness greater than that of the stabilizing section; and a proximal section. Each of the stabilizing section and the sealing section are self-expanding between a radially expanded state when free from an externally applied radial force and a radially constricted state when subject to the externally applied radial force; each of the stabilizing section and the sealing section while in the radially expanded state have a maximum outer diameter larger than an outer diameter of each of the distal section, the intermediate section, and the proximal section.