195 results about "Embolism" patented technology

The invention discloses a thrombus excision system. An embolus is extracted through a mechanical embolus extraction device, a blood vessel is dredged, and revascularization of the blood vessel is achieved. A saccule guide catheter is put at the near end of the embolus part when the embolus is extracted, blood flow is temporarily blocked, and thus a fine crushed embolus generated in the embolus extraction process is prevented from being flushed to the far end of the blood vessel; meanwhile, for a relatively large embolus, a part of thrombus can also be sucked by virtue of the saccule guide catheter, and then the residual thrombus can be extracted by virtue of a thrombus exsector. The thrombus exsector, the saccule guide catheter and a delivery microcatheter are arranged on the thrombus excision system disclosed by the invention, wherein the thrombus exsector is used as a main component, an excision spring is arranged, and the release state of the excision spring is a conical spiral state. Compared with the prior art, the thrombus excision system has the advantages that the thrombus exsector is very soft, the minimal through size is 0.014' (0.36mm), the thrombus exsector can easily enter a cerebral vessel, a near-end protection technology is adopted in the operation process, and thrombus suction is combined with mechanical embolus extraction, so that the success rate of the operation is improved, and the complications are reduced.

The invention discloses a venous thrombosis risk assessment method based on a large language model, and relates to the technical field of medical artificial intelligence, and the method comprises the steps: collecting thoracic surgery diagnosis and treatment data of a patient, carrying out the space-time alignment, generating a standard diagnosis and treatment data flow, and carrying out the homomorphic encryption of the standard diagnosis and treatment data flow, and forming an encrypted patient data package; inputting the encrypted patient data packet into a multi-task large language model, performing feature extraction and semantic coding by a feature coding layer, performing time sequence modeling and risk probability calculation by a risk quantification layer, and outputting a venous thromboembolism risk level of a patient; and performing feature decoupling and potential space mapping on the encrypted patient data packet to obtain thrombus semantic potential features. Through the multi-task large language model, the dual machine learning algorithm and the homomorphic encryption, the accuracy of venous thrombosis risk early warning is improved, and the safety of the risk assessment process is enhanced.

The invention relates to the field of medical information technology and medical data analysis, in particular to a VTE risk prediction method and system based on multi-modal data fusion and dynamic risk modeling, and the system comprises a first feature extraction module, a second feature extraction module, a two-stage risk assessment module and a final risk judgment module. According to the application, through integration of clinical diagnosis and treatment, iconography and genomics data, a deep learning algorithm, a dynamic weight adjustment mechanism and a graph neural network technology are utilized to realize accurate prediction of the VTE risk of the active-stage lung cancer patient. And meanwhile, the problem of cross-mechanism data distribution difference is solved by adopting transfer learning, and the generalization ability of the model is improved. The method can significantly improve the prediction accuracy, reduces the manual intervention demands, and optimizes the medical resource distribution efficiency.

A computer-implemented method of predicting a status of an embolization procedure on an aneurism, includes: receiving (S110) projection image data (110) representing temporal blood flow in a region of the anatomy including the aneurism during the embolization procedure; inputting (S120) the received projection image data (110) into a neural network (120) trained to predict temporal blood flow (130), wherein the neural network (120) is trained to predict temporal blood flow (130) using training data (140) representing temporal blood flow in a region of the anatomy that does not include an aneurism; and in response to the inputting (S120): generating (S130) an output (160) indicative of the status of the embolization procedure based on the predicted temporal blood flow.

A method of providing embolic protection for carotid stent implantation includes advancing an arterial sheath into an arterial system of a patient and advancing a venous sheath into a venous system of the patient. A fluid connection may be established between the venous sheath and the arterial sheath to enable retrograde flow of blood through the arterial sheath. The artery sheath may be advanced through the vasculature into the patient's carotid artery and the inflatable balloon may be inflated within the patient's carotid artery to block smooth blood flow therein. An interventional tool may be advanced through the interior lumen of the arterial sheath, the interventional tool sized such that a portion of the cross-sectional area of the interior lumen of the arterial sheath remains open for retrograde flow of blood.

A system for transvascular delivery to an aortic arch of a patient includes an embolic protection device, a connector mechanism, and a catheter or sheath for delivering the embolic protection device to a working zone. The embolic protection device includes a support frame having a distal portion and a proximal portion, and a filter member attached to the support frame and configured for preventing embolic materials from passing there through. At least one of the distal portion and the proximal portion includes a spring section configured for providing a radial force between the support frame and a wall of the aortic arch when in an expanded state. The embolic protection device is pivotable axially but not radially relative to the connector mechanism.

The thrombus aspiration catheter comprises a catheter body and a deformation structure, and the deformation structure comprises a plurality of supporting rings and deformation assemblies arranged between every two adjacent supporting rings; when the axial distance between every two adjacent supporting rings is reduced, the deformation assembly deforms inwards in the radial direction, and the deformation assembly and the two adjacent supporting rings jointly form a variable-diameter channel with the inner diameter firstly decreasing and then increasing from far to near. When the axial distance between every two adjacent supporting rings is increased, the deformation assemblies deform and recover in the radial direction, and the minimum inner diameter of a channel formed by the deformation assemblies and the two adjacent supporting rings is correspondingly increased. The variable-diameter channel can form mechanical wrapping and clamping on the thrombus at the position with the minimum inner diameter, and thrombus escape or far-end embolism in the suction process is effectively prevented; meanwhile, the structure is beneficial for forming a negative pressure enhancing cavity at the far end of the catheter body, and stable grasping and concentrated efficient suction of the thrombus are achieved.

Provided are methods of contraception using as a first line combined oral contraceptive (COC), a COC composition comprising nomegestrol acetate (NOMAC) and estradiol or an ester thereof. Said COC compositions are associated with a lower risk of venous thromboembolism (VTE) as compared to other CHCs. The compositions may also be used in methods of treatment in women having conditions linked to menstruation and / or fertility.

The application provides a long-acting, non-embolism filling monodisperse chitosan microsphere, the base material of the microsphere is cross-linked chitosan, the cross-linked chitosan is formed by cross-linking reaction of component A and a cross-linking agent, or formed by cross-linking reaction of component A, component B and the cross-linking agent; the component A is at least one of chitosan and modified chitosan, and the component B is at least one of hyaluronic acid, collagen and gelatin; the particle size of the microsphere is 20-120 mu m, and the variation coefficient of the microsphere particle size is not more than 5%. The application also provides a preparation method of the microsphere. The monodispersity of the microsphere is excellent, the degradation time is relatively longer, the water absorption performance is good, the embolism risk can be reduced, the filling effect maintaining time can be prolonged, and the effect of improving wrinkles can be increased, and the problems of short filling effect maintaining time and easy to cause blood vessel embolism of the filling hyaluronic acid product used in the existing medical and beauty field can be solved.

The application discloses a peripheral blood vessel intervention thrombus-removing catheter with a distal embolism protection structure and relates to the technical field of blood vessel thrombus-removing catheters.The peripheral blood vessel intervention thrombus-removing catheter with the distal embolism protection structure comprises a catheter body, one end of the catheter body is provided with a thrombus-removing assembly, the surface of the catheter body is provided with a thrombus-removing assembly, the inside of the catheter body is provided with a transmission assembly, the thrombus-removing assembly comprises a protection pipe network fixedly installed on one side of the catheter body.The transmission assembly is arranged, in the process of use, the rotation of a lead screw can drive one end of the lead screw to move the one side of the filter screen plate to the inside of the protection pipe network, so that the protection pipe network is expanded, and the air bag piece can be inflated, the catheter is placed into in the process of use, the preparation time of catheter operation is reduced, the catheter is convenient to operate, the thrombus-removing and protection operation of the catheter are improved, and the use convenience of the catheter is improved.

An embolic protection system for delivering, deploying, and retrieving a filter configured to capture particles that may become dislodged during a medical procedure. The embolic protection system may include an embolic protection device that captures the particles, a delivery catheter assembly for delivering the embolic protection device to a target location within the vasculature, and a retrieval catheter assembly for retrieving the embolic protection device, along with the captured particles, from the target location after use. The embolic protection device includes a filter movably connected to a guidewire, such that after deployment, the filter can move both axially and rotationally relative to the guidewire, thereby reducing the risk of vasospasm or vascular dissection.

Tubular braided implantable endovascular embolization device including a folded over tubular braid forming a folded over atraumatic distal surface and preformed into multiple distinct sections including: a stabilizing section; a sealing section; an intermediate section interposed between the sealing and stabilizing sections; and a proximal section. The stabilizing section and the sealing section are radially self-expanding to a maximum outer diameter larger than the intermediate section or the proximal section. Enhanced stiffness while obstructing open space regions maximizing disruption of blood flow therethrough is achieved by using a plurality of nested layers (at least one of which is the folded over tubular braid) to form the sealing section while the stabilizing section preferably formed by a single braided layer (i.e., the folded over tubular braid) optimizes compressibility and positioning.

An endovascular embolization system including a braided implantable device having: a tubular braid pre-formed as a default shape into multiple distinct sections including: an intermediate section interposed directly between a stabilizing section and a sealing section; the intermediate section having a stiffness greater than that of the stabilizing section; and a proximal section. Each of the stabilizing section and the sealing section are self-expanding between a radially expanded state when free from an externally applied radial force and a radially constricted state when subject to the externally applied radial force; each of the stabilizing section and the sealing section while in the radially expanded state have a maximum outer diameter larger than an outer diameter of each of the distal section, the intermediate section, and the proximal section.

The utility model relates to a diameter-variable blood vessel sheath structure, which solves a series of problems of large operative wound, incapability of intraoperative radiography and the like in the process of treating lower limb artery embolism by opening a Fogarty catheter to take thrombus. The device comprises an outer sheath, an inner sheath and a sheath core which are sequentially nested from outside to inside, the outer sheath comprises an outer sheath main body and an outer sheath base arranged at the near end of the outer sheath main body; the inner sheath comprises an inner sheath body, an inner sheath base is arranged at the near end of the inner sheath body and connected with a hemostasis valve, the far end of the inner sheath body is connected with a self-expansion covered stent sample structure with two open ends, and the length of the inner sheath is larger than that of the outer sheath. The sheath core comprises a sheath core body, a sheath core base is arranged at the near end of the sheath core body, a conical end with the outer diameter gradually reduced is arranged at the far end of the sheath core body, a middle hole for a guide wire to penetrate through is formed in the sheath core body, and the length of the sheath core is larger than that of the inner sheath. The utility model has the advantages of high effectiveness, high safety, strong adaptability, good adaptability, simple structure and convenient operation.

Active medicine materials of the traditional Chinese medicine composition comprise saffron, nutmeg, clove, sandalwood and apium graveolens according to the weight ratio of 100: n1-n2: n3-n4: n5-n6: n7-n8, n1, n2, n3, n4, n5, n6, n7 and n8 are all natural numbers, n1 is larger than or equal to 100 and smaller than or equal to 300, n3 is larger than or equal to 100 and smaller than or equal to 400, n5 is larger than or equal to 200 and smaller than or equal to 800, n7 is larger than or equal to 50 and smaller than or equal to 400, and n7 is larger than or equal to 400. The composition can prevent, treat, slow down or control stroke-heart syndrome, middle cerebral artery embolism and myocardial injury of subjects, and has popularization prospects.

The utility model relates to a disposable arteriovenous blood taking needle which comprises a transfer block, an arterial needle head, a venous needle head, a blood transfusion tube, a blood outlet tube and embolism blocks, the embolism blocks are sleeved on the outer side faces of the arterial needle head and the venous needle head, the arterial needle head and the venous needle head are jointly connected with the blood transfusion tube, and the transfer block is jointly connected with the blood transfusion tube and the blood outlet tube. Under the combined action of an expansion piece, a stress plate, a partition ring, a partition piece and a butt joint block in the transfer block, the blood transfusion tube and the blood outlet tube in the transfer block can be connected only once, and then irreversible damage can be generated at the joint of the blood transfusion tube and the blood outlet tube after use; meanwhile, a deformation block, a rubber plug, a solid film and a limiting opening are arranged in the embolism block, so that the artery needle head and the vein needle head can deform, the needle heads are blocked, and repeated use of the blood taking needle can be effectively prevented.

This invention discloses an intestinal fungus Saccharomyces cerevisiae M7015 and its applications belong to the field of microbial technology. Saccharomyces cerevisiae The accession number for M7015 is GDMCC No. 66195. This invention first demonstrated, using a mouse subcutaneous stroma embolism model, that the aforementioned strain can promote angiogenesis; secondly, using mouse and Bama miniature pig myocardial infarction models, it was found that the aforementioned strain can promote collateral angiogenesis in ischemic areas of the heart and improve cardiac function. This invention not only fully elucidates... Saccharomyces cerevisiae M7015 promotes the formation of collateral vessels in the heart and improves cardiac function, and also reveals the broad application prospects of this bacterium in the treatment of vascular diseases.

This invention discloses an intelligent trunk infusion device and an infusion dynamic balancing system, belonging to the field of seedling maintenance technology. The invention includes an infusion tank, an adjustment box, and a control module. It replenishes the nutrient solution in the infusion tank without removing it, and simultaneously adds nano-selenium particles through the inlet, enhancing the seedlings' cold and drought resistance. A PID processing unit combines target parameters and real-time data to perform multi-dimensional analysis and response to infusion errors, enabling rapid and accurate adjustment of the infusion pump's operating status, maintaining stable infusion processes, and effectively reducing catheter embolism caused by fluctuations in infusion parameters. The infusion dynamic adjustment unit adjusts the infusion pump power in real-time according to adjustment commands and promptly switches the diversion valve state according to return commands, handling nutrient solutions with abnormal temperatures. This effectively avoids infusion failures caused by unstable infusion flow rates and abnormal nutrient solution temperatures, improving the infusion system's self-adaptability.

The present application provides a stent for intravascular placement that can balance the blood flow preservation of a branch vessel and the embolism of a tumor mouth. The stent for intravascular placement has a tubular strut (11) that can be expanded in diameter, and a polymer film (21) that covers the entire strut (11). A plurality of through-holes (22) are formed in the polymer film (21), the through-holes (22) communicate the inside of the cylinder of the stent for intravascular placement with the outside of the cylinder, the opening size is 0.02 mm or more but 0.2 mm or less, the opening occupancy rate is 25% or more but 41% or less, and the division surface density is 9.5 / mm or more but 30 / mm or less.

The present disclosure provides an embolic protection device comprising a metal wire or metal ribbon with an elliptical or flat cross-section, pre-formed into a spiral structure wound around its short axis. The formed embolic protection device can be deployed within a tubular object and introduced into the target blood vessel through the tube. The elasticity of the material enables it to revert to a predetermined shape, thereby effectively intercepting emboli. The device is characterized by a smaller curvature, enhanced recovery to the preset shape, and reduced interference with blood flow.

The invention relates to a blood vessel plug assembly which comprises a plurality of blood vessel plug units which are connected in series in the axial direction. The blood vessel plug unit comprises a filling core made of biological compressible materials, a woven shell wrapping the outside of the filling core, and a center connecting rod axially penetrating through the filling core. The two ends of the central connecting rod are fixedly connected with the end parts of the woven shell, so that the filling core is restrained and packaged in the woven shell; the woven shell is formed by weaving shape memory material wires, so that the blood vessel plug unit can be compressed to the first radial size and can be conveyed through the sheathing canal, and after the blood vessel plug assembly is released from the sheathing canal, the woven shell is self-expanded to the second radial size, so that the woven shell is attached to the blood vessel wall; and the filling core is driven to unfold together to form an embolism body so as to block blood flow of blood vessels. Conveying through the sheathing canal is facilitated, and the anchoring stability in the blood vessel can be ensured.

This invention provides a multifunctional medical thrombectomy device. The variable-diameter guide wire, from distal to proximal, consists of a coarse-diameter distal winding wire, a fine-diameter distal winding wire, and a variable-diameter core wire. The delivery tube, from distal to proximal, consists of a distal marker, a collecting umbrella, a connecting marker, a thrombectomy net, a proximal marker, and the main body of the delivery tube. The variable-diameter core wire is inserted into the delivery tube. The coarse-diameter and fine-diameter distal winding wires exit from the distal end of the delivery tube. An inner limiter is fixed to the variable-diameter core wire at a position adjacent to the proximal end of the distal marker, and an inner limiter is fixed to the variable-diameter core wire at a position adjacent to the proximal end of the connecting marker. The outer diameter of the inner limiter is larger than the inner diameters of the distal and connecting markers, and the outer diameter of the inner limiter is larger than the inner diameters of the connecting and proximal markers. The outer diameter of the coarse-diameter distal winding wire is larger than the inner diameter of the distal marker. The length of the variable-diameter core wire is shorter than the length of the collecting umbrella, and the length of the collecting umbrella is shorter than the length of the thrombectomy net. This technical solution integrates the thrombectomy support, embolism protection system, and guide wire into one unit, simplifying the thrombectomy process and thus improving the success rate.

The embodiment of the present application provides a kind of heart intervention suturing device, the device includes: first puncture part, second puncture part, suture part and driving mechanism, by the driving mechanism control the first puncture part will be through the first puncture part of the tissue near the to-be-sutured site is collected into the second tube, and the tissue near the to-be-sutured site is gathered in the first puncture part collection into the second tube;Meanwhile, by the driving mechanism control the first tube drives the second puncture part towards the first puncture part direction movement, until the second puncture part penetrates the tissue near the to-be-sutured site and is fixed on the second tube, and the to-be-sutured site is sutured by the first end and the second end of the suture part.The to-be-sutured site is sutured by the suturing device provided in the embodiment of the present application, there is no residual implant in the patient's body, there is no inherent risk of septum occlusion, there is no embolism caused by implant, and there is no risk of arrhythmia and the like.

The invention discloses a low-voltage nanosecond pulse platform waveform fitting method, and belongs to the technical field of high-frequency pulse control, and the method comprises the steps: obtaining a set voltage value, calculating the optimal pulse width corresponding to a target cell through a transmembrane voltage formula according to the set voltage value, and calculating the optimal pulse width according to a dose and transmembrane potential accumulation model. Calculating the number of equivalent nanosecond pulse sub-pulses capable of replacing the optimal pulse width, calculating the number of pulse strings according to the total dose set by the optimal pulse width and the number of the equivalent nanosecond pulse sub-pulses, fitting nanosecond pulses, and replacing the optimal pulse width, the calculated nanosecond fitting value, the calculated pulse string number and preset parameters are stored in a storage chip of the pulse platform, the pulse platform calls the storage parameters for energy emission, the low-voltage nanosecond platform can be used for achieving the combined effect of a microsecond platform and a high-voltage nanosecond platform, released bubbles are smaller than those of the microsecond platform, the occurrence rate of embolism is reduced, and the service life of the microsecond platform is prolonged. The released voltage is lower than that of traditional nanoseconds, and the problems of blood fusion and smooth muscle and nerve damage are reduced.

The utility model provides a cutting woven covered stent, which relates to the technical field of medical instruments, and comprises a cutting skeleton, a woven mesh and an ePTFE membrane, the cutting skeleton is designed by combining an open loop and a closed loop, and the two ends of the stent have a good anchoring effect in vivo; and the middle part is of an open-loop structure, and through the support of the woven mesh, the whole body has good support performance and also has flexibility. The stent composed of the cutting framework, the woven mesh and the ePTFE membrane is arranged, the cutting framework is designed by combining an open loop and a closed loop, and the two ends of the stent have a good anchoring effect in the body; and the middle part is of an open-loop structure, and through the support of the woven mesh, the whole body not only has good support performance, but also has flexibility. The outer layer is coated with the ePTFE membrane, so that the coverage area on plaques is larger, the probability that the plaques fall off from stent meshes can be effectively reduced, and micro-embolism after the plaques fall off is prevented. The ePTFE membranes on the inner layer and the outer layer are dip-coated with the drug-loaded coatings, proliferation of vascular smooth muscles is inhibited, and intravascular restenosis is prevented.

This application relates to a coronary sinus and left atrium shunt system, belonging to the field of medical device technology. The system described in this application, by setting up a puncture component and a shunt component including a cutter, allows for the cutting of a portion of myocardial tissue between the coronary sinus and the left atrium, forming a shunt orifice. This establishes a shunt channel between the coronary sinus and the left atrium, effectively avoiding the embolism risk associated with atrial septal shunts and improving coronary artery blood perfusion, potentially benefiting myocardial recovery.

Embolic protection device (1) inside a blood vessel (10) comprising a filament preformed as a double conical spiral structure with a first peripheral zone (2) formed by a floppy (3) followed by a first set of coils (4) in the form of a cone; a central zone (5) formed by at least one central coil and a second peripheral zone (6), following the central zone (5), formed by a second set of coils (7) and a terminal means (8) located at the end of the second set of coils (7), wherein the second set of coils (7) is movable from an open position to a closed position, forming a cone of ascending diameter in the direction of blood flow inthe openposition , and a cone of descending diameter in the direction of blood flow through the central zone (5) in the closed position.

Embodiments relate to a method for assisting the diagnosis of cardioembolic stroke, in which the method is performed by a processor and is to assist the diagnosis of cardioembolic stroke by using chest radiographic images, the method comprising the steps of: acquiring chest radiographic images to be classified of a subject; and acquiring cardioembolic stroke diagnosis auxiliary information from the chest radiographic images to be classified of the subject, by using a neural network model, wherein the neural network model is configured to extract features from the chest radiographic images to be classified of the subject, and determine, based on the extracted features, whether the subject belongs to a group indicative of having cardioembolic stroke.

The application discloses a filter screen, a stent microcatheter system for embolism of intracranial ruptured aneurysm, and relates to the technical field of medical devices, which comprises a catheter body, a balloon and a supporting filter screen; the balloon and the supporting filter screen are arranged on the catheter body at intervals; the two ends of the supporting filter screen are respectively provided with a fixed ring and a moving ring; the fixed ring is sleeved on the catheter body and is fixedly connected with the catheter body; the moving ring is sleeved on the catheter body and is slidably connected with the catheter body; a traction rope is fixedly connected with the moving ring; the traction rope penetrates through the fixed ring and extends outward; a traction ring is fixedly connected with the extending end; and a positioning spring is arranged between the fixed ring and the moving ring. Through the arrangement, the application provides a novel microcatheter system which is reasonable in structure and convenient to adjust; the balloon and the supporting filter screen are arranged in zones, and the temporary blood vessel occlusion and the aneurysm neck protection blocking functions can be realized respectively.