264 results about "Plasma viscosity" patented technology

The invention relates to the field of medical materials and medical instruments, and discloses a dry bioprosthetic valve and a preparation method thereof.The preparation method comprises the following steps that S1, pericardium and a cross-linking agent solution are mixed for a cross-linking reaction; s2, carrying out first dehydration treatment on the crosslinked pericardium by adopting a first dehydration solution with gradually increased concentration gradient under an ultrasonic condition; and S3, carrying out second dehydration treatment on the pericardium subjected to the first dehydration treatment by adopting a second dehydration solvent, so as to obtain the dried bioprosthetic valve. According to the preparation method provided by the invention, ethanol, isopropanol and water in a specific proportion are adopted to prepare a dehydration solution with gradient concentration, and two-step dehydration drying is carried out in combination with the physical effect of an ultrasonic technology and glycerol, so that rapid rehydration of the bioprosthetic valve is realized, and the original shape and mechanical property of the bioprosthetic valve can be better recovered after rehydration; and the immediate hemodynamic stability of the valve is improved.

The invention relates to the technical field of medical monitoring, and discloses an intelligent monitoring device for a blood return end of hemodialysis, the device is in communication connection with a dialyzer for hemodialysis, and the device comprises an alarm trigger module, a temperature compensation module and a screen display module. According to the application, the alarm triggering module accurately monitors the blood return temperature, the blood return flow velocity and the induced blood flow velocity, captures abnormity in real time and triggers alarm; the temperature compensation module not only guarantees life safety of the patient, but also improves temperature control adaptability; the screen display module displays core parameters and trend curves in real time, space limitation is broken through, and medical workers are assisted in remote quick response; the portability of the device is realized by the micro clamping and fixing module; the clinical flexibility is enhanced through threshold adjustment; the power-on self-test further ensures the operation safety of the equipment; therefore, full-process optimization from data monitoring, intelligent control to remote monitoring is realized, and accurate, safe and personalized dialysis support is provided for patients.

A blood pump-oxygenator system (250A, 250B, 250C) for increasing perfusion and oxygen levels in the body of a patient (P), comprising: a blood inlet (80) and a blood outlet (90) connected to form a circuit operable as a cardiopulmonary bypass system suitable for extracorporeal treatment of the blood of the patient; a first blood pump (11) and a first oxygenator (20), wherein the first blood pump (11) is configured to deliver blood from the patient (P) through the circuit to the blood inflow port (80), through the first oxygenator (20), out of the blood outflow port (90) and back to the patient (P). The system further comprises a second blood pump (13) and a second oxygenator (21), wherein the second blood pump (13) is configured to deliver blood from the patient (P) through the circuit to the blood inflow port (80), through the second oxygenator (20), out of the blood outflow port (90) and back to the patient (P). The circuit comprises a first branch (101) and a second branch (102) arranged in parallel with each other, the first branch (101) accommodating the first blood pump (11) and the first oxygenator (20), and the second branch (102) accommodating the second blood pump (13) and the second oxygenator (21). The system further comprises a pump control unit (290) wherein the first and second blood pumps (11, 13) are configured to be controlled by the pump control unit (290) to increase or decrease the blood flow through the corresponding oxygenator (20, 21) by changing the proportion of the blood flow through the first and second oxygenator (20, 21).

The invention provides a balloon endoscopic system for intravascular direct vision examination, and relates to the technical field of medical instruments, the balloon endoscopic system comprises a catheter, a balloon capable of being filled and discharged, an endoscope lens, a light source assembly and an image transmission processing module, a cavity channel used for containing the endoscope lens and a conduction component of the light source assembly is formed in a catheter body of the catheter, and the catheter body of the catheter is internally provided with a cavity channel used for containing the endoscope lens and the conduction component of the light source assembly; the filling pipeline is used for supplying liquid to the inflatable and deflatable balloon; the inflatable and deflatable balloon is fixedly connected to the outer surface of the front end of the catheter, and the inflatable and deflatable balloon is used for bulging after being conveyed to a target position in a blood vessel. The inflatable and deflatable balloon can block blood flow and open the blood vessel wall after bulging and is matched with transparent filling liquid injected into the filling pipeline, residual blood can be further removed, a blood-free observation window is formed, interference of blood on imaging is avoided, and a foundation is laid for clearly observing the condition of the blood vessel wall. The inner wall of the balloon is coated with a nano anti-fog coating, so that the penetrability of a light source is ensured, and the fogging surface influence caused by blood residue or temperature difference can be avoided.

This invention discloses a blood purification device and medical system. The blood purification device includes: a device housing; a blood purifier; a blood tubing assembly, the blood tubing assembly including a first blood tubing connecting a human blood vessel to the inlet of the blood purifier and a second blood tubing connecting the outlet of the blood purifier to the human blood vessel; a power assembly including a blood pump for driving blood flow within the blood tubing assembly, a first replenishment pump for allowing anticoagulant solution to flow into the first blood tubing, and / or a second replenishment pump for allowing calcium solution to flow into the second blood tubing; and a blood component analysis component disposed within the device housing, the blood component analysis component being used to detect collected blood samples. This design facilitates the appropriate adjustment of anticoagulant drugs and calcium ions in the blood purification circuit.

A containing element is used to capture material in a blood vessel for removal. The containing element is advanced through the blood vessel or a catheter in a constricted configuration. A control body is coupled to the containing element which assists moving the containing element. In some embodiments, the containing element is used for restricting blood flow within a vessel.

The present invention provides a traditional Chinese medicine composition for clearing heat, removing blood stasis, stopping bleeding and regulating menstruation, and a preparation method thereof, relating to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition of the present invention comprises the following components: catalpol, aucubin, β-sitosterol, emodin, chrysophanol, sanguisorba officinalis extract, Panax notoginseng saponins, septamine, cuttlefish scaly, rubiacin, typhaneuroside, and p-coumaric acid; the components synergistically work together to significantly reduce plasma prothrombin time and plasma recalcification time, and significantly reduce the whole blood viscosity, plasma viscosity, and hematocrit of rats with blood stasis syndrome. The traditional Chinese medicine composition of the present invention is used in the preparation of drugs for menstrual disorders or menstrual bleeding and metrorrhagia, and has a significant therapeutic effect on irregular menstruation, excessive menstrual bleeding, or metrorrhagia.

The invention relates to the field of medical instruments and public health, in particular to an artificial blood vessel with anticoagulation, endothelium promotion and bending resistance functions and a preparation method of the artificial blood vessel, and the artificial blood vessel is used for various blood vessel replacement and blood vessel bypass operations and has the characteristics of anticoagulation, endothelium promotion and bending resistance. The copper-containing material and the degradable magnesium-based metal material are respectively integrated on the inner surface of the artificial blood vessel and in the interlayer of the vessel wall, so that the functions of anticoagulation, endothelium promotion and bending resistance of the artificial blood vessel are realized. According to the artificial blood vessel with the anticoagulation, endothelium promotion and bending resistance functions, in the initial stage of use, due to the spiral structure of the magnesium alloy wire, the blood vessel cannot collapse after being bent, the blood flow is kept smooth, copper ions, magnesium ions and a small amount of hydrogen can be released to surrounding tissues in the use process, the microenvironment of the surrounding tissues is adjusted to be alkalescent, and the blood circulation is kept smooth. Through the synergistic effect of the copper ions and the magnesium alloy, the effects of promoting endothelialization, resisting blood coagulation and adjusting the acid-base property of the microenvironment are achieved at the same time, and therefore the functions of resisting blood coagulation, promoting endothelium and resisting bending are achieved.

The invention relates to the technical field of blood purification, in particular to an anticoagulation pump which comprises a bottom plate, an injection pushing mechanism and a liquid medicine feeding mechanism, a hemodialysis machine is fixedly installed on the upper side of the bottom plate, a blood drawing pipe is fixedly arranged on one side of the hemodialysis machine, and an infusion tube is fixedly arranged on the other side of the hemodialysis machine; a round seat frame and a box body are fixedly connected to the upper side of the bottom plate, an injector is clamped in the round seat frame, heparin can be supplemented to the injector through the injection pushing mechanism, the injector, the box body and a piston rod, heparin can be continuously injected, blood is prevented from being coagulated in the hemodialysis machine, and the hemodialysis efficiency is improved. The hemodialysis purification device has the advantages that smooth flow of blood is guaranteed, the injector does not need to be replaced, time and labor are saved during operation, long-time interruption of heparin injection is avoided, improvement of the anticoagulation effect of hemodialysis purification is facilitated, the hemodialysis purification process can be smoothly performed, and meanwhile, the working efficiency of the anticoagulation pump is improved.

The invention relates to an intravascular blood pump comprising a pumping device having a pump portion and a drive portion, wherein the pump portion comprises a pump housing having a primary blood flow inlet and a primary blood flow outlet hydraulically connected by a primary passage, and the drive portion comprises a stator and a rotor rotatable about a rotational axis and configured to rotate a primary impeller configured to convey a primary blood flow along the primary passage from the primary blood flow inlet to the primary blood flow outlet, the drive portion further comprising a secondary blood flow inlet and a secondary blood flow outlet hydraulically connected by a secondary passage extending through an axial gap between the rotor and the stator and a secondary impeller arranged at a drive portion end of the rotor and rotatable about the rotational axis together with the rotor.

A system may include an outer frame. A system may include an expandable member, wherein the expandable is at least one or both of: disposed in the outer frame, and coupled to a lumen of the outer frame. A system may include a compressible bladder. A system may include a conduit configured to fluidly couple the expandable member to the compressible bladder, wherein forcing an inflation fluid from the compressible bladder to the expandable member is configured to manipulate the expandable member to a restricted blood flow state and forcing the fluid from the expandable member to the compressible bladder is configured to manipulate the expandable member to an unrestricted blood flow state.

The utility model provides a bubble catcher and a blood purification system, and relates to the technical field of medical equipment.The bubble catcher comprises a shell, the shell comprises a top wall and a first side wall, the first side wall is obliquely arranged relative to the top wall, a liquid inlet hole is formed in the top wall, the first side wall is located on the extension side in the axial direction of the liquid inlet hole, and the first side wall is located in the extension side in the axial direction of the liquid inlet hole; liquid flowing out of the liquid inlet hole can fall on the first side wall; the fixing part is arranged on the outer wall of the shell, and the fixing part is used for being fixedly connected with the outside. According to the bubble capturer provided by the embodiment of the invention, the installation work of the bubble capturer can be simplified, and the situation that bubbles are generated or blood cells are damaged due to large fall during blood return can be reduced; meanwhile, due to the fact that the first side wall which is obliquely arranged can play a certain buffering role when the blood flows into the bubble catcher, the blood flow speed can be further increased, and the blood coagulation condition can be reduced.

The utility model discloses an instrument for negative pressure extraction and filtration of thrombus of an artery. Comprising a sheathing canal, a blocking balloon, a blood collection bag, a pipeline and a negative pressure providing structure, the blocking balloon is arranged on the outer side of the thrombus treatment sheathing canal, then the blood collection bag is connected to the outer side of the sheathing canal through the pipeline, the sheathing canal is connected with the blood collection bag through the pipeline, and a thrombus filter screen is arranged in the pipeline; a negative pressure providing structure is further arranged, the negative pressure providing structure is a structure with a cavity which is arranged on the outer side of the blood collection bag and used for constructing negative pressure by extracting gas in the blood collection bag, power is provided through the negative pressure to lead blood in the arterial blood vessel out into the blood collection bag, and thrombus is blocked at the position of the filter screen after the blood passes through the thrombus filter screen. The filtered safe blood flows into the blood collecting bag, the blood in the blood collecting bag can be transfused back to the patient again in a transfusing mode, and the blood in the blood collecting bag can also provide a blood source for substances for extracting platelet rich plasma (PRP) therapy.

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for promoting blood circulation to remove meridian obstruction and a preparation method and application thereof. The traditional Chinese medicine composition for promoting blood circulation to remove meridian obstruction is prepared from the following raw materials in parts by weight: 15 to 25 parts of herba taxilli, 18 to 22 parts of semen cuscutae, 8 to 15 parts of radix angelicae sinensis, 3 to 6 parts of radix salviae miltiorrhizae, 18 to 22 parts of radix dipsaci, 8 to 15 parts of herba leonuri, 12 to 18 parts of radix paeoniae alba, 25 to 35 parts of rhizoma dioscoreae, 6 to 12 parts of rhizoma chuanxiong, 3 to 8 parts of radix aucklandiae, 6 to 12 parts of fructus nelumbinis, 10 to 15 parts of radix scutellariae and 12 to 20 parts of roasted rhizoma atractylodis macrocephalae. The traditional Chinese medicine composition obtained through the composition, the dosage and the proportion of the components can remarkably reduce the whole blood viscosity, hematocrit and plasma viscosity of a rat with a blood stasis syndrome, can remarkably reduce the twisting frequency of an experimental dysmenorrhea model rat, has the effects of activating blood, resisting inflammation, dredging collaterals and relieving pain, and has the effect superior to that of each pair of components.

The invention relates to an intravascular blood pump (1) comprising a pumping device (11) having a pump portion (3) and a drive portion (4), wherein the pump portion (3) comprises a pump housing (2) having a primary blood flow inlet (211) and a primary blood flow outlet (22) hydraulically connected by a primary passage (30) and the drive portion (4) comprises a stator (40) and a rotor (41) rotatable about a rotational axis (10) and configured to rotate a primary impeller (31) configured to convey a primary blood flow along the primary passage (30) from the primary blood flow inlet (211) to the primary blood flow outlet (22), the drive portion (4) further comprises a secondary blood flow inlet (23) and a secondary blood flow outlet (24), the secondary blood flow inlet (23) and the secondary blood flow outlet (24) are hydraulically connected by a secondary passage extending through an axial gap (401) between the rotor (41) and the stator (40) and a secondary impeller (42) arranged at a drive portion end (DSE) of the rotor (41) and rotatable about the rotational axis (10) together with the rotor (41), the secondary impeller (42) comprises one or more secondary impeller blades (421) configured to convey a secondary blood flow along the secondary passage from the secondary blood flow inlet (23) to the secondary blood flow outlet (24) in a direction towards a pump portion end (PSE) of the pumping device (11), the rotor (41) is mounted in a blood cleaning radial slide bearing (47) having an inner rotor bearing surface (4211) and an outer rotor bearing surface (4311), and the secondary impeller (42) forms the inner rotor bearing surface (4211) of the radial slide bearing (47).

The utility model discloses a container shell for a blood filter, which is characterized in that a second shell is inserted into one side of a first shell, a volume cavity is formed by the first shell and the second shell, and a filter membrane is arranged on the inner side of the volume cavity; a first flow guide structure is arranged on the inner wall of the first shell, a second flow guide structure is arranged on the inner wall of the second shell, and the first flow guide structure and the second flow guide structure guide liquid in the volume cavity; according to the device, the flow channels of the liquid inlet and the liquid outlet are additionally arranged, the flow guide structures are arranged on the two sides of the flow channels, blood enters the liquid inlet, flows out of the first flow channels and diffuses to the upper surface of the whole filter membrane along a path formed by the first flow guide structures arranged in the first shell in parallel, the blood filtering path is prolonged, the filter membrane and the edge part are fully utilized, and the blood filtering efficiency is improved. The second flow guide structure is arranged continuously or discontinuously and corresponds to the position of the part, with the maximum blood flow, of the liquid inlet.

An oxygenerator (4) has a blood side (2), a gas side (6) and a semi-permeable membrane (8), where the membrane (8) separates the blood side (2) from the gas side (6), the blood side (2) has an inlet (18) and an outlet (20), the gas side (6) has an inlet (14) and an outlet (16), and during operation of the oxygenerator (4), the gas side (6) has an inlet (14) and an outlet (16). A flow of gas flows into the inlet (14) to the outlet (16) at a gas flow rate and a flow of blood flows into the inlet (18) to the outlet (20) at a blood flow rate, where gas flowing into the inlet (14) of the gas side (6) and blood flowing into the inlet (18) of the blood side (2) flow along the membrane (8) in the same direction to their respective outlets (16, 20).

The utility model discloses a fixed blood sampling device, and relates to the technical field of medical blood sampling. The fixed blood sampling device comprises a blood sampling needle, a tail needle, a connecting piece and a filter element, the connecting piece is made of a transparent material, a flowing channel is formed in the connecting piece, the fixed ends of the blood sampling needle and the tail needle are fixed to the flowing channel in a sealed mode, and the filter element can adjust the communication relation between internal air of the connecting piece and external air; when the filter element does not make contact with liquid, the communication relation between internal gas of the connecting piece and external air is opened, blood of a patient can flow out more easily under the action of atmospheric pressure, when the filter element makes contact with the liquid, the communication relation between the internal gas of the connecting piece and the external air is closed, and the blood flows through the connecting piece; meanwhile, medical staff can know the flowing condition of the blood by observing the connecting piece made of the transparent material, and the collecting end of the tail needle punctures the protective sleeve in time and then is inserted into the vacuum blood collecting tube, so that the blood collection is completed.

Provided is a method and a system for noninvasive measurement of blood viscosity based on oxygen saturation and blood flow rate, which may easily and quickly calculate the blood viscosity by using the method and the system for noninvasive measurement of blood viscosity based on oxygen saturation and blood flow rate, thereby enabling immediate obtaining of the blood viscosity.

A medical device and method used for patient temperature management, wherein the device is designed to cool the patient's head and blood flow to the head and neck including the two carotid and the two vertebral arteries of a patient after trauma in order to prevent inflammation and reduce swelling in the brain. It is portable with a rapid cooling capability feature, does not require an ICU setting, eliminates certain complications that could affect the patient otherwise, and can be quickly and easily placed on the patient with little training or expertise.

The invention belongs to the technical field of pipeline fixing devices, and particularly relates to a cardiac surgery extracorporeal circulation pipeline fixing system which comprises a fixing base and a pipeline clamping module located at the top of the fixing base, and the pipeline clamping module comprises a fixing plate. The device is tightly adsorbed to the surface of an operating table through a fixed suction cup, a second supporting seat is automatically leveled through a hydraulic buffer, the second supporting seat is always in a horizontal stable state, and a first clamping block and a second clamping block are controlled to be buckled through a pipeline clamping module by extruding arc-shaped clamping plates on the two sides; a first clamping block and a second clamping block are fixed through rotation of a limiting block, a pipeline is preliminarily fixed, pressure adjusting plates on the two sides are controlled by a pressure adjusting knob to move in the opposite direction, and the clamping force can be finely adjusted according to the factors such as the material and thickness of the pipeline; the problem that the blood flow stability is influenced by the body position change of a patient or the traction of a surgical instrument and other factors of the pipeline fixing device in the surgical process is solved.

Devices and methods divert blood flow from a first vessel to a second vessel and maintain blood flow in the first vessel. The device includes a first segment and a second segment. The first segment is configured to anchor in the first vessel. The first segment includes a window to allow blood to flow into the first segment, through the window, and distal in the first vessel. The second segment is configured to anchor in the second vessel. The second segment is configured to allow blood to flow into the first segment, through the second segment, and into the second vessel.

The invention discloses a temperature-controllable magnetic separation blood transfusion pipeline, and belongs to the technical field of blood separation pipelines. The blood transfusion pipeline comprises an inner-layer pipe and an outer-layer sleeve arranged on the periphery of the inner-layer pipe in a sleeving mode. A gap between the inner-layer tube and the outer-layer sleeve is arranged to be a first channel and is used for transporting a cooling medium, and the inner-layer tube is arranged to transport blood to be separated; one end of the inner-layer pipeline is provided with a non-return tip, one side of the non-return tip is provided with a non-return bead, and the non-return bead and the non-return tip are sequentially arranged in the blood transportation direction. The non-return ball and the non-return tip are matched with each other, so that only blood can pass through the non-return ball, and magnetized cells or non-magnetic particles with relatively large particle sizes are prevented from entering back-section blood circulation; the first channel directly cools the blood flowing through the inner-layer tube, the cooling efficiency is high, cooling is uniform, heat exposure of the blood is reduced to the maximum extent from the path, and the heat injury risk is reduced.

According to the bleeding cage and the blood pump thereof, the blood mixing loss can be reduced, the supporting strength is good, the whole bleeding cage is in a circular tube shape, a far-end opening of the bleeding cage forms a blood inlet, a bleeding opening and a flushing outlet are formed in the outer wall of the bleeding cage, and the bleeding opening and the flushing outlet are formed in the axial direction at intervals. Normal blood pumped by the blood pump flows out from the blood outlet, and flushing fluid flows out from the flushing outlet after flushing the gap, so that energy loss caused by blood mixing is reduced, and the hydraulic performance of the blood pump is improved; the bleeding cage has a certain length in the axial direction, and the bleeding opening and the flushing outlet are arranged at an interval, so that the overall structural strength of the bleeding cage is ensured, and the bleeding cage is prevented from being deformed due to stress; meanwhile, the turbulence influence generated when blood flows through the bleeding cage is reduced, stable rotation of the magnet is improved, and then the rotation stability of the whole blood pump is guaranteed.

Provided is a hemostasis operation assistance system capable of more reliably preventing the occurrence of a complete occlusion of a blood vessel during a hemostasis operation. A hemostasis operation assistance system (100) is provided with: a detection unit (130) that detects information relating to blood flow before a hemostasis operation is started; a control unit (140) that determines a compression condition on the basis of the detection result of the detection unit; and a drive unit (150) that adjusts the amount of compression in accordance with the compression conditions.

This utility model belongs to the field of medical device technology, specifically relating to a double-lumen central venous catheter with anti-wall adhesion and anticoagulation functions, including an extension tube, a double-lumen catheter, and a connector; the extension tube is connected to the double-lumen catheter through the connector; the double-lumen catheter is divided into two inlet lumens by a diaphragm, and the two inlet lumens are connected to two corresponding extension tubes; a side hole and a main hole are provided at the end of the double-lumen catheter, and the end of the double-lumen catheter has a C-shaped segment, with the side hole located on the concave side of the C-shaped segment, and the main hole located at the end of the double-lumen catheter. The C-shaped segment in this design reduces the occurrence of the side hole adhering to the blood vessel wall, reducing the probability of local coagulation and thrombosis when used for pediatric hemodialysis blood drainage; the biomimetic sharkskin microgrooves etched on the outside of the double-lumen catheter reduce resistance to blood flow and thrombus formation; the biomimetic sharkskin microgrooves can be filled with covalently grafted sulfonated heparin-hydrogel, continuously releasing anticoagulant factors, further reducing the formation of wall-attached thrombi.

The present application relates to the field of medical devices, in particular to a self-perfusion drug-eluting balloon and a self-perfusion drug-eluting device, the self-perfusion drug-eluting balloon comprising a balloon body, the balloon body extending axially and being open at both ends, a blood flow channel being arranged along the axial direction of the balloon body, the blood flow channel being arranged on the wall of the balloon body, the balloon body comprising an outer balloon and an inner balloon arranged in the outer balloon, the blood flow channel being arranged on the wall of the outer balloon. The self-perfusion drug-eluting device comprises the self-perfusion drug-eluting balloon and a delivery assembly. The self-perfusion drug-eluting balloon does not block blood flow in the inflated state, avoiding the situation that the physical rebound of the blood vessel is fast due to short-time adhesion and short support time.

The present invention is applicable to the field of medical device technology and provides a delivery system including an outer sheath assembly, an inner sheath assembly, and a sealing assembly. The outer sheath assembly includes an outer sheath core tube, the inner sheath assembly includes an inner sheath core disposed within the outer sheath core tube, and the sealing assembly includes a first sealing member disposed between the inner sheath core and the outer sheath core tube to seal the gap between the proximal end of the outer sheath core tube and the inner sheath core. The present invention can effectively block blood flowing between the outer sheath core tube and the inner sheath core, preventing blood from flowing out of the product and solving the technical problem of product leakage.

This utility model relates to a blood vessel occlusion device, which includes a support body, a membrane covering the support body and forming a hollow cavity with closed ends together with the support body, multiple isolation membranes arranged axially at intervals in the hollow cavity and dividing the hollow cavity into several independent chambers, and expansion particles filling each chamber. The membrane has several through holes that connect the hollow cavity to the external environment and allow water molecules to pass through. Water in the blood enters the hollow cavity through the through holes. The expansion particles inside absorb water in the blood and expand, thereby forming a stable and reliable support for the support body, making the device fit more closely to the blood vessel, effectively enhancing the anchoring performance of the device, and significantly reducing the risk of device displacement caused by blood flow impact. The isolation membranes divide the hollow cavity into several chambers, which can prevent the expansion particles from being unevenly distributed in the cavity.