16 results about "Blood oxygenation" patented technology

The application provides a small blood oxygenator, belonging to the technical field of oxygenators, which comprises a shell, an oxygenator core body arranged in the shell, an upper end cover and a lower end cover respectively arranged on the vertical two sides of the shell, a liquid inlet connector connected to the lower end of one side of the shell, a liquid outlet connector connected to the upper end of the other side of the shell, an air inlet connector connected to the upper end cover, an air outlet connector connected to the lower end cover, and the liquid inlet connector, the liquid outlet connector, the air inlet connector and the air outlet connector are respectively connected with corresponding external channels through a butt joint structure. The application solves the problem that the air inlet, the air outlet, the liquid outlet and the liquid inlet of the existing small oxygenator are mostly connected with the corresponding external pipeline through a wire connection method when in use, and the positions of the air inlet, the air outlet, the liquid outlet and the liquid inlet are mostly connected with each other through a rubber ring to realize the leakage prevention function, the leakage prevention effect is not good, leakage may occur, and the normal use of the oxygenator cannot be guaranteed.

An extracorporeal membrane oxygenation (ECMO) system including a blood oxygenator having an outer shell surrounding an oxygenator fiber bundle, a heating element, a closed loop control system, and a temperature sensor. The blood oxygenator defining a blood inlet and a blood outlet. The blood oxygenator has a blood flow path that is bifurcated between a first channel and a second channel. The heating element disposed around or within the outer shell. The closed loop control system configured to regulate the heating element. The temperature sensor is electronically linked to the control system. The heating element extends alongside at least one of the first channel and the second channel.

Systems and methods for determining oxygen consumption using magnetic resonance imaging (MRI) are provided. In some implementations, a method includes steps for applying a pulse sequence using an MRI system to a region of interest (ROI) in a subject, and acquiring magnetic resonance (MR) signal data from the ROI using the MRI system. The method also includes steps for reconstructing the MR signal data using a reconstruction algorithm to derive at least one motion-controlled, blood oxygenation-weighted image, and at least one blood-flow image; and analyzing the at least one motion-resolved, blood oxygenation-weighted image to determine oxygen consumption in the ROI.

This invention discloses a label-free real-time blood vessel tracking method driven by dynamic blood oxygenation features, relating to the fields of medical image processing and computer vision. The method includes: acquiring dynamic blood oxygenation signals from a target tissue region; preprocessing the blood oxygen concentration change data; constructing a spatiotemporal matrix of blood oxygenation features; performing adaptive feature extraction using an improved 3D convolutional neural network; establishing a multi-scale blood vessel contour prediction model; dynamically predicting and updating the blood vessel contour using a Kalman filter algorithm; outputting the real-time trajectory of the blood vessel center and boundary contours; and introducing a dynamic feedback mechanism to achieve continuous and stable blood vessel tracking. This invention achieves highly secure blood vessel tracking, significantly improving tracking accuracy, robustness, and real-time performance under tissue movement and complex background interference by utilizing dynamic blood oxygenation features.

This invention discloses a FA-ICG-NBs nanobubble, its preparation method, and its application in the preparation of tumor-targeted therapeutic agents. The FA-ICG-NBs nanobubble employs a composite phospholipid shell, with folic acid (FA) covalently bonded to the surface and indocyanine green (ICG) loaded onto it, encapsulating a mixture of oxygen and sulfur hexafluoride. The preparation method includes: preparing a lipid solution for forming the composite phospholipid shell; mixing the lipid solution with the oxygen and sulfur hexafluoride mixture, and then performing a reciprocating shearing gas-liquid interface self-assembly to obtain the FA-ICG-NBs nanobubble. The FA-ICG-NBs nanobubble prepared by this invention utilizes dual-wavelength photoacoustic imaging for non-invasive assessment of tumor blood oxygenation and hypoxia improvement, combined with ICG fluorescence timing for screening the optimal therapeutic window, and synergistic oxygen-enhanced sonodynamic therapy. It exhibits good biocompatibility, structural stability, and integrates targeted enrichment, blood oxygenation assessment, hypoxia monitoring, timing regulation, and enhanced therapeutic effects.

A method (200) for determining the total flow rate of exhaust gas exiting a gas exchange device (110) coupled to the circulatory system of a patient (10) is disclosed. The gas exchange device is configured to provide oxygen-rich blood to the circulatory system by exposing oxygen-deficient blood to oxygen provided by an incoming gas and to allow the passage of excess oxygen into the exhaust gas. The method involves the step of determining the total flow rate of exhaust gas from the concentration and flow rate of oxygen leaving the gas exchange device. The concentration is recovered from a sensor, while the flow rate is determined based on a mass equilibrium approach, and the amount of oxygen leaving the gas exchange device corresponds to the difference between the amount of oxygen supplied to the gas exchange device and the amount of oxygen absorbed by the blood during gas exchange.

This invention discloses an energy-saving control method and device for a bird tracker based on sensor fusion. The method uses an accelerometer to collect triaxial acceleration data to identify the bird's behavioral state, activating the heart rate and blood oxygenation sensors only when the bird is stationary and deactivating them during movement. It combines illumination data, location information, and the device's real-time time to determine signal obstruction environments and dynamically adjusts the operating strategies of the positioning and communication modules. Before positioning calculation, it detects the number of satellites in a low-power mode, performing full positioning only when the target is met. Power management independently controls the on / off operation of the positioning, communication, and storage modules, with standby power supplied only to the real-time clock module. The corresponding device includes a main control unit, a sensor data acquisition and tracking unit, and an energy-saving control unit, integrating multiple types of sensors and a power management module. This invention significantly reduces the tracker's ineffective power consumption and extends its battery life in the field through multi-sensor fusion and dynamic energy-saving scheduling, adapting to the long-term monitoring needs of birds.

This invention relates to the field of intelligent decision-making technology, and discloses a multimodal sleep apnea detection method, device, equipment, and medium. The method includes: acquiring radar signals and the target user's blood oxygenation signal and sleep posture signal; fusing the radar signal, blood oxygenation signal, and sleep posture signal into a multimodal continuous signal; segmenting the multimodal continuous signal window to obtain signal segments; extracting multimodal physiological fusion features from the signal segments; classifying the signal segments into respiratory event types based on the multimodal physiological fusion features; applying rule constraints to correct the respiratory event types to obtain corrected respiratory event types; and using the corrected respiratory event types as the sleep apnea detection result. By classifying the signal segments into respiratory event types, the objectivity and accuracy of the detection results are improved; and by applying rule constraints to correct the respiratory event types, the detection results are made more in line with clinical standards, improving the reliability and practicality of the results.

The invention provides a concentration assessment and training guidance system based on multi-physiological signal fusion, which is characterized in that an electroencephalogram signal, a heart rate signal and a blood oxygen signal are acquired by a non-invasive brain-computer device, and time synchronization and data preprocessing are performed on the acquired multi-source physiological signals; a multi-signal fusion evaluation module in the system performs fusion calculation on the preprocessed signals to generate a concentration evaluation result of the user; the concentration judgment module judges the concentration state of the user based on the evaluation result, and provides personalized training suggestions through the training guidance module; the system also has a closed-loop feedback mechanism, and can adjust the training content, strength and duration in real time according to the change of the concentration state. In addition, different evaluation and training strategies can be adopted according to the characteristics of different application crowds (such as students and old people), and the method has high scene adaptability and practical value.

This invention discloses a miniature wearable vital sign monitoring device, comprising: a shell, including an end cap and a base, the end cap being detachably connected to the top of the base, forming a mounting cavity between the end cap and the base; a power supply system, including a charging coil, a rechargeable battery, and a power management circuit; a processing and communication unit, including an electronic circuit board and a signal conditioning communication unit; a sensing system, including a heart rate and blood oxygenation chip, a temperature chip, a motion chip, an acceleration chip, and a positioning chip; and an adhesion module, fixed to the bottom of a connector; wherein the microprocessor unit integrates an edge computing module, a communication module, and an early warning module. The device integrates heart rate and blood oxygenation, temperature, motion, respiration, and positioning monitoring functions into one unit, providing coherent and complete data support for a comprehensive assessment of health status.

A method (200) for determining a total flow rate of exhaust gas leaving a gas exchange device (110) coupled to a circulatory system of a patient (10) is disclosed. The gas exchange device is configured to provide oxygen-rich blood to the circulatory system by exposing oxygen-poor blood to oxygen provided by an inlet gas and to allow excess oxygen to enter the exhaust gas. The method involves determining the total flow rate of the exhaust gas from a concentration and a flow rate of oxygen leaving the gas exchange device. The concentration is retrieved from a sensor, while the flow rate is determined based on a mass balance approach, wherein the amount of oxygen leaving the gas exchange device corresponds to the difference between the amount of oxygen supplied to the gas exchange device and the amount of oxygen taken up by the blood during gas exchange.

A system (100, FIG. 1) for controlling blood oxygenation in a patient using an oxygenator 200 having a gas-blood interface 240. The system (100, FIG. 1) comprises a controller (150, FIG. 1) configured to receive a measured value of a physiological parameter indicative of the oxygenation of the patient's blood and calculate a difference between the measured value and a target value of the physiological parameter. The controller (150, FIG. 1) is further configured to control a gas supply apparatus (300, FIG. 1) to: supply a first oxygenation gas (242a) to a first interface region (240a) of the gas-blood interface (240) and supply a second oxygenation gas (242b) to a second interface region (240b) of the gas-blood interface (240); responsive to the measured value being above the target value, decrease the amount of oxygen to which the blood is exposed by reducing the flow rate of the second oxygenation gas (242b) to reduce the difference; and responsive to the flow rate of the second oxygenation gas (242b) being reduced to a threshold value, reduce the concentration of oxygen in and / or the flow rate of the first oxygenation gas (242a).

An oxygenator including a housing defining an interior having improved gas exchange fluid pathways and / or heat exchange fluid pathways is disclosed. In some instances, the oxygenator includes a gas exchange fluid pathway for passing a gas sequentially from a gas exchange fluid inlet, through one or more layers of gas exchange fibers extending in a first direction, through one or more layers of gas exchange fibers extending in a second direction, and out a gas exchange fluid outlet. In some instances, the oxygenator includes a partition dividing the interior between a gas exchange chamber and a gas-and-heat exchange chamber. In some instances, the housing includes an insulating fluid barrier chamber configured to be filled with a flowing heat exchange fluid from the heat exchange fluid inlet to provide an insulating barrier between outflow ends of the gas exchange fibers and the gas exchange fluid outlet.

1. Name of the product in this design: Watch (2415). 2. Purpose of this design: for displaying time, heart rate, and blood oxygenation, etc. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D rendering 1.

A system 100 for controlling blood oxygenation in a patient. The system comprises an oxygenator 200 configured to receive blood from the patient and to expose the blood to an amount 124 122 of oxygen as the blood passes through the oxygenator 200 to produce oxygenated blood. The system 100 further comprises a sensor 110 positioned downstream of the oxygenator 200 and configured to 120 measure a saturation of oxygen present in the oxygenated blood. The system 100 further comprises a controller 150. The controller 150 is configured to receive the measured saturation of oxygen from the sensor 110, calculate a difference between a target saturation of oxygen and the measured saturation of oxygen, and adjust the amount of oxygen to which the blood is exposed in the oxygenator 200 to reduce the difference.

This invention relates to the field of postoperative care for finger replantation and discloses a digitally controlled real-time temperature-regulating device for replanted fingers. The device includes a housing and a lid hinged to the housing. The front of the housing has an arc-shaped entrance for the patient's arm to enter, and a partition is fixedly connected to the bottom of the inner cavity of the housing. This digitally controlled real-time temperature-regulating device generates a vertically uniform laminar flow of hot air through an aerodynamic laminar flow heat exchange mechanism, avoiding the localized overheating problem of traditional radiant heating. A flexible, conformal microcirculation pulsation mechanism actively promotes blood return and microcirculation perfusion by pulsating and squeezing the replanted finger at a simulated human heart rate frequency. A multimodal tissue activity monitoring mechanism captures the temperature distribution, blood flow velocity, and blood oxygenation data of the replanted finger in real time. The central controller dynamically adjusts the heating power and pulsation frequency based on the monitoring data, forming a closed-loop control of "monitoring-feedback-adjustment," significantly improving the prevention of vascular crises.