58 results about "Blood oxygenation" patented technology

The utility model provides a small blood oxygenator which comprises a shell, an upper end cover and a lower end cover, the upper end cover and the lower end cover are arranged at the two ends of the shell, an oxygenator core is arranged in the shell, an air inlet is formed in the upper end cover, an air outlet is formed in the lower end cover, the air inlet and the air outlet are located on the two sides of the oxygenator core respectively, and a liquid outlet and a liquid inlet are formed in the shell respectively. The liquid outlet and the liquid inlet are located in the two sides of the oxygenator core respectively, a gap is formed between the periphery of the oxygenator core and the inner ring of the shell, a liquid medium can flow into the gap from the liquid outlet and flow out of the gap from the liquid inlet, and the liquid outlet is located above the liquid inlet. According to the small blood oxygenator, all functional components of the oxygenator are independent parts, shaping production is facilitated, an integrated mold does not need to be arranged, the development cost and the production cost are reduced, assembling is convenient, the production efficiency is not affected, the liquid outlet, the liquid inlet, the air inlet and the air outlet are formed in different parts, adjustment is convenient, and use is convenient. Therefore, different use conditions can be adapted.

The application provides a small blood oxygenator, belonging to the technical field of oxygenators, which comprises a shell, an oxygenator core body arranged in the shell, an upper end cover and a lower end cover respectively arranged on the vertical two sides of the shell, a liquid inlet connector connected to the lower end of one side of the shell, a liquid outlet connector connected to the upper end of the other side of the shell, an air inlet connector connected to the upper end cover, an air outlet connector connected to the lower end cover, and the liquid inlet connector, the liquid outlet connector, the air inlet connector and the air outlet connector are respectively connected with corresponding external channels through a butt joint structure. The application solves the problem that the air inlet, the air outlet, the liquid outlet and the liquid inlet of the existing small oxygenator are mostly connected with the corresponding external pipeline through a wire connection method when in use, and the positions of the air inlet, the air outlet, the liquid outlet and the liquid inlet are mostly connected with each other through a rubber ring to realize the leakage prevention function, the leakage prevention effect is not good, leakage may occur, and the normal use of the oxygenator cannot be guaranteed.

1. The name of the design product: membrane oxygenator. 2. The use of the design product: for replacing the function of the lung to oxygenate blood and remove carbon dioxide. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view 1.

Methods and devices for increasing oxygenation levels in the blood supply and thereby treating the condition of hypoxemia. Multiple approaches such as pressure reduction in the pulmonary circulatory system, reducing triggering mechanisms in the main pulmonary artery and restricting flow in the pulmonary circulatory system are disclosed. Interventions associated with those approaches can including shunting, restrictors, compliance devices, pharmacologic substances, etc.

An extracorporeal membrane oxygenation (ECMO) system including a blood oxygenator having an outer shell surrounding an oxygenator fiber bundle, a heating element, a closed loop control system, and a temperature sensor. The blood oxygenator defining a blood inlet and a blood outlet. The blood oxygenator has a blood flow path that is bifurcated between a first channel and a second channel. The heating element disposed around or within the outer shell. The closed loop control system configured to regulate the heating element. The temperature sensor is electronically linked to the control system. The heating element extends alongside at least one of the first channel and the second channel.

The present disclosure provides methods and apparatus for evaluating the flow of blood in damaged or healing tissue. The present disclosure also provides methods of identifying a patient at the onset of risk of pressure ulcer or at risk of the onset of pressure ulcer, and treating the patient with anatomy-specific clinical intervention selected based on perfusion or blood oxygenation values, or a combination thereof. The present disclosure also provides methods of stratifying groups of patients based on risk of wound development and methods of reducing incidence of tissue damage in a care facility. The present disclosure also provides methods to analyze trends of perfusion or oxygenation measurements to detect tissue damage before it is visible, and methods to compare bisymmetric perfusion values to identify damaged tissue.

Systems and methods for determining oxygen consumption using magnetic resonance imaging (MRI) are provided. In some implementations, a method includes steps for applying a pulse sequence using an MRI system to a region of interest (ROI) in a subject, and acquiring magnetic resonance (MR) signal data from the ROI using the MRI system. The method also includes steps for reconstructing the MR signal data using a reconstruction algorithm to derive at least one motion-controlled, blood oxygenation-weighted image, and at least one blood-flow image; and analyzing the at least one motion-resolved, blood oxygenation-weighted image to determine oxygen consumption in the ROI.

This invention discloses a label-free real-time blood vessel tracking method driven by dynamic blood oxygenation features, relating to the fields of medical image processing and computer vision. The method includes: acquiring dynamic blood oxygenation signals from a target tissue region; preprocessing the blood oxygen concentration change data; constructing a spatiotemporal matrix of blood oxygenation features; performing adaptive feature extraction using an improved 3D convolutional neural network; establishing a multi-scale blood vessel contour prediction model; dynamically predicting and updating the blood vessel contour using a Kalman filter algorithm; outputting the real-time trajectory of the blood vessel center and boundary contours; and introducing a dynamic feedback mechanism to achieve continuous and stable blood vessel tracking. This invention achieves highly secure blood vessel tracking, significantly improving tracking accuracy, robustness, and real-time performance under tissue movement and complex background interference by utilizing dynamic blood oxygenation features.

Systems and methods are described for assessing arterial blood oxygen saturation concurrently with performing continuous blood pressure monitoring via a volume clip approach. Generally, the cuff system may be configured to fit to a body appendage. The cuff system may include a pressurizable balloon and a photoplethysmograph. The method may perform arterial blood oxygen saturation when the artery of the body appendage is in an unloaded state. Small fluctuations in the plethysmogram signal may be used with the calculated calibration factor to calculate arterial blood oxygen saturation.

The invention relates to the technical field of medical apparatus and instruments, and particularly discloses an integrated membrane type oxygenator which comprises a blood storage cylinder, an oxygenator body, a membrane assembly, an oxygenator cover, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe, an oxygen supply pipe and an oxygen supply pipe, the oxygenation shell comprises a variable-temperature silk membrane structure and an oxygenation silk membrane structure from inside to outside, the fluid optimization structure is arranged in the oxygenation shell and used for optimizing the blood flowing state or purifying blood, the oxygenation shell is provided with a blood outlet pipe, the blood outlet pipe is arranged close to the lower cover, and the lower cover is provided with a water inlet pipe; by integrating the blood storage cylinder, the oxygenator body and the fluid optimization structure, the integrated function of blood storage, oxygenation and flowing or purification is achieved, the basic structure is adaptive to various clinical scenes, and the integration level and practicability of the device are improved.

A system (100, FIG. 1) for controlling blood oxygenation of a patient using an artificial lung 200 having a gas-blood interface 240. The system (100, FIG. 1) includes a controller (150, FIG. 1) configured to receive a measurement of a physiological parameter indicative of oxygenation of the patient's blood and to calculate a difference between the measurement and a target value of the physiological parameter. The controller (150, FIG. 1) is further configured to control the gas supply device (300, FIG. 1) to supply the first oxygenated gas 242a to the first interface area 240a of the gas-blood interface 240 and the second oxygenated gas 242b to the second interface area 240b of the gas-blood interface 240, to reduce the amount of oxygen the blood is exposed to by reducing the flow rate of the second oxygenated gas 242b to reduce the difference in response to the measured value exceeding a target value, and to reduce the oxygen concentration and / or flow rate of the first oxygenated gas 242a in response to the flow rate of the second oxygenated gas 242b being reduced to a threshold value.

A cordless, wireless system for providing the long-term collection of medical data that may be used in digital ECG analysis, that includes a retaining element that retains a sensor in close proximity or adjacent to a user's skin and an intelligent measuring head that obtains the information provided by the sensor and transmits the obtained information to a processing system. The processing system collates the obtained information and determines from the collated data a digital ECG response and further a blood pressure based on blood oxygenation level.

Disclosed is a blood oxygenator for a premature fetus comprising a housing defining a cavity therein, wherein the housing comprises a blood inlet, a blood outlet, a gas inlet, and a gas outlet; and a gas exchanger disposed within the cavity, wherein the gas exchanger comprises a plurality of hollow fibers arranged in a pattern allowing blood to flow past the hollow fibers when in contact with the hollow fibers, wherein the hollow fibers comprise a receiving end in communication with the gas inlet for receiving a sweep gas and an emitting end in communication with the gas outlet from which the sweep gas exits, wherein the oxygenator is designed to rely on the fetal heart as sole blood pump.

This invention discloses a FA-ICG-NBs nanobubble, its preparation method, and its application in the preparation of tumor-targeted therapeutic agents. The FA-ICG-NBs nanobubble employs a composite phospholipid shell, with folic acid (FA) covalently bonded to the surface and indocyanine green (ICG) loaded onto it, encapsulating a mixture of oxygen and sulfur hexafluoride. The preparation method includes: preparing a lipid solution for forming the composite phospholipid shell; mixing the lipid solution with the oxygen and sulfur hexafluoride mixture, and then performing a reciprocating shearing gas-liquid interface self-assembly to obtain the FA-ICG-NBs nanobubble. The FA-ICG-NBs nanobubble prepared by this invention utilizes dual-wavelength photoacoustic imaging for non-invasive assessment of tumor blood oxygenation and hypoxia improvement, combined with ICG fluorescence timing for screening the optimal therapeutic window, and synergistic oxygen-enhanced sonodynamic therapy. It exhibits good biocompatibility, structural stability, and integrates targeted enrichment, blood oxygenation assessment, hypoxia monitoring, timing regulation, and enhanced therapeutic effects.

The present disclosure relates to a diffusion device, such as a blood oxygenator or gas exchanger, and a process for its production. The diffusion device is used in the removal of carbon dioxide from blood.

The utility model discloses an invalid circulation prevention extracorporeal membrane oxygenation cannula which comprises a drainage tube body, and a blocking balloon assembly is arranged on the outer surface of the drainage tube body. The blocking balloon assembly comprises two blocking balloons, a connecting pipe is connected between the two blocking balloons, two communicating holes are formed in the connecting pipe and communicated with the two blocking balloons respectively, the safety of intubation is improved, meanwhile, it is effectively guaranteed that unoxygenated superior vena cava blood and unoxygenated inferior vena cava blood are drained to be oxygenated outside the body, and therefore the safety of intubation is improved. The function of preventing ineffective circulation through single-tube oxygenation is achieved, compared with traditional double-tube oxygenation, the situation that blood which is infused back just after oxygenation is repeatedly drained out of the body, and ineffective oxygenation is caused can be avoided, and the effectiveness of blood oxygenation is ensured.

A method (200) for determining the total flow rate of exhaust gas exiting a gas exchange device (110) coupled to the circulatory system of a patient (10) is disclosed. The gas exchange device is configured to provide oxygen-rich blood to the circulatory system by exposing oxygen-deficient blood to oxygen provided by an incoming gas and to allow the passage of excess oxygen into the exhaust gas. The method involves the step of determining the total flow rate of exhaust gas from the concentration and flow rate of oxygen leaving the gas exchange device. The concentration is recovered from a sensor, while the flow rate is determined based on a mass equilibrium approach, and the amount of oxygen leaving the gas exchange device corresponds to the difference between the amount of oxygen supplied to the gas exchange device and the amount of oxygen absorbed by the blood during gas exchange.

This invention relates to the field of computer system technology based on specific computational models, and discloses a blood oxygen change monitoring algorithm that integrates dynamic Bayesian modeling. The algorithm includes: quantifying signal uncertainty by calculating the entropy value of the harmonic energy distribution of the pulse waveform; driving a dynamic Bayesian network based on this entropy value to perform confidence evaluation and weighted processing on the blood oxygen estimation model; and finally outputting a decision pair containing the estimated blood oxygen value and its confidence value. This invention transforms signal uncertainty into a calculable entropy index, enabling the system to autonomously distinguish between real physiological changes and measurement noise, avoiding the misjudgment problem caused by motion interference in traditional blood oxygen monitoring. Simultaneously, it utilizes the continuous learning capability of Bayesian networks to achieve seamless personalized calibration, significantly improving the reliability and practicality of medical-grade wearable devices.

A system for calculating cardiac output of a patient on an extracorporeal blood oxygenation circuit, such as veno-venous extracorporeal membrane oxygenation, includes determining (i) a first arterial carbon dioxide content or surrogate and (ii) a first carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the first removal rate of carbon dioxide from the blood; establishing a second removal rate of carbon dioxide from the blood in the oxygenator in the extracorporeal blood oxygenation circuit; determining (i) a second arterial carbon dioxide content or surrogate and (ii) a second carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the second removal rate of carbon dioxide from the blood; and calculating a cardiac output of the patient corresponding to a blood flow rate through the extracorporeal blood oxygenation circuit, the first arterial carbon dioxide content or surrogate, the first carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the first removal rate of carbon dioxide from the blood; the second arterial carbon dioxide content or surrogate and the second carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the second removal rate of carbon dioxide from the blood.

Processing functional magnetic resonance imaging (fMRI) data using one or more machine learning - artificial intelligence (ML - AI) models is described. The method comprises: obtaining blood-oxygen-level-dependent (BOLD) signals associated with changes in blood oxygenation and blood flow in a brain of a subject; determining the fMRI data for the subject based on the BOLD signals; generating jack-knife datasets from the fMRI data using a jack-knife correlation process that removes one or more data points associated with the regions of the brain from the fMRI data to generate each of the jack-knife datasets; processing the jack-knife datasets and the fMRI data using the one or more ML - AI models to generate predicted correlation strengths for each region of the brain for a plurality of time steps; and outputting information associated with the predicted correlation strengths.

This invention discloses an energy-saving control method and device for a bird tracker based on sensor fusion. The method uses an accelerometer to collect triaxial acceleration data to identify the bird's behavioral state, activating the heart rate and blood oxygenation sensors only when the bird is stationary and deactivating them during movement. It combines illumination data, location information, and the device's real-time time to determine signal obstruction environments and dynamically adjusts the operating strategies of the positioning and communication modules. Before positioning calculation, it detects the number of satellites in a low-power mode, performing full positioning only when the target is met. Power management independently controls the on / off operation of the positioning, communication, and storage modules, with standby power supplied only to the real-time clock module. The corresponding device includes a main control unit, a sensor data acquisition and tracking unit, and an energy-saving control unit, integrating multiple types of sensors and a power management module. This invention significantly reduces the tracker's ineffective power consumption and extends its battery life in the field through multi-sensor fusion and dynamic energy-saving scheduling, adapting to the long-term monitoring needs of birds.

This invention relates to the field of intelligent decision-making technology, and discloses a multimodal sleep apnea detection method, device, equipment, and medium. The method includes: acquiring radar signals and the target user's blood oxygenation signal and sleep posture signal; fusing the radar signal, blood oxygenation signal, and sleep posture signal into a multimodal continuous signal; segmenting the multimodal continuous signal window to obtain signal segments; extracting multimodal physiological fusion features from the signal segments; classifying the signal segments into respiratory event types based on the multimodal physiological fusion features; applying rule constraints to correct the respiratory event types to obtain corrected respiratory event types; and using the corrected respiratory event types as the sleep apnea detection result. By classifying the signal segments into respiratory event types, the objectivity and accuracy of the detection results are improved; and by applying rule constraints to correct the respiratory event types, the detection results are made more in line with clinical standards, improving the reliability and practicality of the results.

The invention discloses a lung function evaluation method, and belongs to the technical field of rehabilitation monitoring, and the method comprises the steps: obtaining a prostrating ventilation coefficient according to the number of prostrating ventilation times and the total duration of prostrating ventilation; a blood oxygen evaluation coefficient is obtained according to the mean value of the blood oxygenation index difference values before and after lung treatment in the treatment cycle, the blood oxygenation index difference values before and after the treatment cycle and the blood oxygenation index after treatment; obtaining a lung ultrasound evaluation coefficient according to the mean value of the difference values of the lung ultrasound scoring indexes before and after the lung treatment in the treatment cycle, the difference values of the lung ultrasound scoring indexes before and after the treatment cycle and the lung ultrasound scoring indexes after the treatment cycle; a lung function evaluation coefficient is obtained based on the prone ventilation coefficient, the APACHEII score of the patient, the blood oxygen evaluation coefficient and the lung ultrasound evaluation coefficient; constructing a follow-up frequency optimization model based on the lung function evaluation coefficient and the reference follow-up frequency, and outputting and determining a target follow-up frequency; according to the method, individual treatment response is quantified through multi-model cooperation, and the outlier patient management precision is remarkably improved.

A system 100 for controlling blood oxygenation in a patient includes an oxygenator 200 configured to receive blood from a patient and expose the blood to a quantity of oxygen as the blood passes through the oxygenator 200 to produce oxygenated blood. The system 100 further includes a sensor 110 disposed downstream of the oxygenator 200 and configured to measure the oxygen saturation present in the oxygenated blood. The system 100 also includes a controller 150 configured to receive the measured oxygen saturation from the sensor 110, calculate a difference between a target oxygen saturation and the measured oxygen saturation, and adjust the amount of oxygen the blood is exposed to within the oxygenator 200 to reduce the difference.

The invention discloses a physical and mental index dynamic characteristic multi-modal identification analysis system based on artificial intelligence, and relates to the technical field of biomedical signal processing, and the system comprises a multi-source data acquisition module, a dynamic risk assessment module, a blood flow abnormity analysis module, a multi-modal risk layering module and an intelligent early warning module; the multi-source data collection module collects respiration, heart rate and blood oxygen data, the dynamic risk assessment module predicts risks through a long-short-term memory network, the blood flow abnormity analysis module identifies blood flow abnormity through a convolutional neural network, the multi-mode risk layering module assesses the risk level, and the intelligent early warning module generates a report and takes early warning measures. Through multi-modal identification analysis, comprehensive, real-time and accurate monitoring of physical and mental indexes is realized, the risk assessment accuracy is improved, potential health risks are early warned in time, powerful support is provided for clinical decision making, the public health management level is improved, the medical cost is reduced, and the life quality is improved.

A system (100, Figure 1) for controlling blood oxygenation in a patient using an oxygenator 200, the system having a controller (150, Figure 1) configured to control a gas supply apparatus (300, Figur

The device for blood oxygenation includes a gas exchange chamber with passage openings. One side the chamber is connected in a gas-tight manner with the expansion tank feeding the gas mixture containing oxygen to the chamber, having the inlet opening of gas mixture from the feeding installation. The other side of the chamber is connected in a gas-tight manner with the gas mixture discharging tank, having the outlet opening of gas mixture. The inner part of the chamber has a membrane as a capillary bundle permeable to gas mixture particles and non-permeable to blood particles, ends of which are anchored in the passage openings. The capillary bundle is tensed with a tension force and is parallel to the longitudinal axis of the chamber and to each other, or are arranged spirally. The side wall of the chamber has at least one inlet / outlet opening.

The invention provides a concentration assessment and training guidance system based on multi-physiological signal fusion, which is characterized in that an electroencephalogram signal, a heart rate signal and a blood oxygen signal are acquired by a non-invasive brain-computer device, and time synchronization and data preprocessing are performed on the acquired multi-source physiological signals; a multi-signal fusion evaluation module in the system performs fusion calculation on the preprocessed signals to generate a concentration evaluation result of the user; the concentration judgment module judges the concentration state of the user based on the evaluation result, and provides personalized training suggestions through the training guidance module; the system also has a closed-loop feedback mechanism, and can adjust the training content, strength and duration in real time according to the change of the concentration state. In addition, different evaluation and training strategies can be adopted according to the characteristics of different application crowds (such as students and old people), and the method has high scene adaptability and practical value.

This invention discloses a miniature wearable vital sign monitoring device, comprising: a shell, including an end cap and a base, the end cap being detachably connected to the top of the base, forming a mounting cavity between the end cap and the base; a power supply system, including a charging coil, a rechargeable battery, and a power management circuit; a processing and communication unit, including an electronic circuit board and a signal conditioning communication unit; a sensing system, including a heart rate and blood oxygenation chip, a temperature chip, a motion chip, an acceleration chip, and a positioning chip; and an adhesion module, fixed to the bottom of a connector; wherein the microprocessor unit integrates an edge computing module, a communication module, and an early warning module. The device integrates heart rate and blood oxygenation, temperature, motion, respiration, and positioning monitoring functions into one unit, providing coherent and complete data support for a comprehensive assessment of health status.

A system for calculating cardiac output of a patient on an extracorporeal blood oxygenation circuit includes measuring first oxygenated blood flow rate by a pump in the extracorporeal circuit and a corresponding arterial oxygen saturation and recirculation in the extracorporeal circuit, then changing the pump flow rate, such as decreased, to produce a corresponding change in arterial oxygen saturation (wherein such change is outside of normal operating variances or drift), which change in the arterial oxygen saturation and recirculation are measured. From the first flow rate and the second flow rate along with the corresponding measured recirculation and the arterial oxygen saturation, the CO of the patient can be calculated, without reliance upon a measure of venous oxygen saturation. The system also includes an accommodation of oxygenation by the lungs of the patient during the extracorporeal blood oxygenation.