295 results about "Blood processing" patented technology

The invention provides a GelMA microneedle patch loaded with chromogenic gold nano bipyramids and a preparation method thereof.The method comprises the steps that citric acid, chloroauric acid and a CTAC solution are mixed, then sodium borohydride is added, and a seed solution is obtained through stirring and standing; mixing chloroauric acid, silver nitrate, hydrochloric acid and CTAB (cetyltrimethyl ammonium bromide), and sequentially adding ascorbic acid and the seed solution to obtain a growth solution; carrying out centrifugation, morphology regulation and chemical etching purification to obtain a chromogenic gold nano bipyramid solution; the preparation method comprises the following steps: reacting gelatin with methacrylic anhydride in PBS, dialyzing and freeze-drying to obtain GelMA; dissolving GelMA in the gold nanoparticle bipyramid solution, and adding a photoinitiator LAP to obtain a mixed precursor solution; and the GelMA microneedle patch loaded with the gold nano bipyramid is prepared through mold casting, centrifugation, ultraviolet light crosslinking and drying demolding. The microneedle extraction and gold nano bipyramid color development integrated scheme is initiated, blood sampling is not needed, the dermis interstitial fluid is extracted in a minimally invasive mode through the microneedle, detection pain and trauma are reduced, the cross infection risk of blood treatment is avoided, and the microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle

Dialysis systems comprising actuators that cooperate to perform dialysis functions and sensors that cooperate to monitor dialysis functions are disclosed. According to one aspect, such a hemodialysis system comprises a user interface model layer, a therapy layer, below the user interface model layer, and a machine layer below the therapy layer. The user interface model layer is configured to manage the state of a graphical user interface and receive inputs from a graphical user interface. The therapy layer is configured to run state machines that generate therapy commands based at least in part on the inputs from the graphical user interface. The machine layer is configured to provide commands for the actuators based on the therapy commands.

The present disclosure pertains to a media supply arrangement for supplying a medical treatment device with a medium, in particular for supplying an extracorporeal blood treatment device with a dialysis medium, wherein an air conditioning device for air conditioning of a medical treatment device coupled to the media supply arrangement is provided.

The present invention refers to a system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, the invention refers to a container and blood treatment device to be used in a method according to the present invention.

The present invention refers to a system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, the invention refers to a container and blood treatment device to be used in a method according to the present invention.

The utility model belongs to the field of medical instruments, and particularly relates to blood treatment equipment. The blood treatment equipment comprises a blood treatment pond which is a sealed container and is provided with at least one first opening for plasma to enter and at least one second opening for blood to enter and exit; the plasma generator is used for generating plasma, and an outlet of the plasma generator is communicated with the blood treatment pond through the first opening; and the blood passage is communicated with the blood treatment tank through the second opening. According to the equipment disclosed by the invention, the plasma can be used for treating the blood, so that the oxidation resistance of the blood can be improved, and an equipment foundation is provided for the plasma to become a new health-care and treatment means.

A system includes an extracorporeal blood treatment device and a heat exchanger for heat exchange between dialysate flowing from the extracorporeal blood treatment device and permeate to be supplied to the extracorporeal blood treatment device. The extracorporeal blood treatment device and the heat exchanger are configured as separate devices.

A blood purifier includes a porous molded body; exhibits an excellent blood compatibility wherein platelet adherence is inhibited and exhibits a good cytokine adsorption capacity and a low pressure loss before and after blood treatment; and can be safely used. A blood purifier includes a main vessel and a porous molded body housed in the main vessel. The porous molded body contains a hydrophobic polymer and a hydrophilic polymer. The amount of low-melting-point water per 1 g of dry weight of the porous molded body is 0.12 g to 2.00 g. The contact change ratio for the porous molded body is 0% to 0.2%. The ratio L / D is 1.00 to 2.30 where, for the region taken up by the porous molded body in the main vessel, L is the length in the flow direction and D is the circle-equivalent diameter of the cross section in the direction perpendicular to the flow direction.

A blood circulation system for an extracorporeal blood treatment machine includes: an arterial circulation section; a venous circulation section; a dynamic bubble trap; and an air separator. The blood circulation system conducts blood, during the operation of a blood pump of the extracorporeal blood treatment machine, from a patient to a dialysis unit and from the dialysis unit to the patient. The blood circulation system also includes a recirculation or branch line connected to the bubble trap in order to return part of the blood that flows into the bubble trap into the blood circulation system, upstream of the bubble trap. An extracorporeal blood treatment machine includes the blood circulation system.

The present invention relates to a control or regulation device (150) configured to control or regulate the operation of a blood treatment device (100) for treating a patient during a blood treatment period wherein the blood treatment device (100) is connected to an extracorporeal blood circuit (300) and to a blood treatment device, such as a dialyzer (303) or a blood filter. The blood treatment apparatus (100) further comprises a dialysis liquid inlet line (104) and a dialysis liquid outlet line (102), a heating device (162) for heating the dialysis liquid, and one or more temperature sensors (165a, 165b) wherein at least a first temperature sensor (165a) is arranged downstream of the blood treatment device and / or downstream of the dialysis liquid inlet line (104) and at least a second temperature sensor (165b) is arranged downstream of the dialysis liquid outlet line (102). A first temperature value (T1) of a first liquid flowing prior to the dialysis liquid inlet line (104) is determined for determining a second temperature value (T2) of a second liquid flowing prior to the dialysis liquid inlet line (104). Here, the control or regulation device (150) is configured to increase or set the temperature of the dialysis liquid using the heating device (162) on the basis of a first temperature value (T1) determined by the first temperature sensor (165a).

The invention provides a bulb tube current feedback and synchronous irradiation control system in a blood irradiator, and belongs to the technical field of medical irradiation equipment. Comprising a current acquisition module used for processing target blood by a target blood irradiator and outputting a current signal, a signal conditioning module used for carrying out filtering, level conversion and electromagnetic noise suppression processing on the output current signal, and a current control module. An STM32 microcontroller adopts an incremental proportional control algorithm to dynamically adjust output gain of a high-voltage generator, a synchronous irradiation control module, generation of a synchronous control signal and operation of a management module, a target blood irradiator is controlled to enter a low-power-consumption mode in a non-irradiation stage, and the current of a bulb tube is collected in real time and is processed, so that the current of the high-voltage generator is obtained. High precision and stability of the current signal are ensured, a synchronous control signal is generated according to the current signal after signal conditioning and the irradiation process state, and coordination control of sample rotation and radiation output is realized.

The present application relates to an extracorporeal blood treatment system (50) for treating a subject, the system comprising: an extracorporeal blood circuit (52); a dialysate fluid circuit (54); the extracorporeal blood circuit and the dialysate fluid circuit being separated by a membrane (56) of a filtration unit (58); at least one blood pump (60) for controlling the flow of blood through the blood circuit; at least one dialysate fluid pump (62) for controlling the flow of dialysate fluid through the dialysate fluid circuit (54); a system computing unit (64) operatively connected to the blood pump and to the dialysate fluid pump, the system computing unit having at least one input; wherein the system computing unit is adapted to receive a desired blood concentration of glutamine GLN b , to receive a desired blood concentration of glucose GLUCOSE b , and to receive a desired blood concentration of ketone bodies KETONE b ; the system computing unit being adapted to control the blood pump and the dialysate fluid pump such that an actual concentration value of glutamine GLN a is driven to approach GLN b , and an actual concentration value of glucose GLUCOSE a is driven to approach D b , and an actual concentration value of ketone bodies is driven to approach KETONE a . The present application relates to a treatment device for use in an extracorporeal blood treatment system, a method for treating cancer using the system, a controller for controlling the method and a dialysis liquid suitable for use in the method.

The invention discloses a contrast agent filtering device for coronary surgery and a using method thereof, the device is integrally in a plastic bag shape and comprises a filtering bag body, the bottom of the filtering bag body is provided with a transfusion connector and a blood transfusion connector which are provided with sealing covers, and an inner opening is sleeved with a filter screen support with a filter screen; the filter bag body is divided into a filter area and an adsorption particle storage area through a middle seal, a flushing connector and a hanging hole are arranged at the top, and the filter bag body can be matched with a vibration disc for use. The use method comprises the steps that blood containing a contrast agent is extracted and input into the filtering area, the middle seal is opened through pressing, the blood makes full contact with the adsorption particles through vibration or manual extrusion so as to adsorb the contrast agent, then the filtered blood is infused back, and residual plasma can be infused back after being diluted with normal saline. The device is simple in structure, low in cost and easy and convenient to operate, the filtering effect is improved by 30% compared with the prior art, the adsorption rate reaches 75%-85%, contrast agents in blood can be effectively removed, damage to the kidney of a patient is reduced, and the device is particularly suitable for blood treatment of the patient after coronary angiography.

The invention provides a filtering device for animal slaughtering blood treatment and a treatment method, and relates to the field of animal slaughtering blood treatment.The filtering device comprises a filtering assembly, the filtering assembly is composed of a flow channel mechanism and a control mechanism, the flow channel mechanism is of a double-working-flow-channel design, different flow channel sets can be switched for use through the control mechanism, and the flow channel sets are connected with the control mechanism; therefore, the animal slaughtering blood can be filtered, the filter frame and a filter screen in the filter frame can be washed and cleaned on the premise that the filter frame is not detached, the blood filtering precision and efficiency are effectively guaranteed, the limitation that traditional equipment needs to be shut down to be detached and cleaned is broken through, and the practicability is high. The problems that a filter plate frame of an existing slaughter blood filter device is arranged in the filter device, a backflushing structure is not arranged, and after a filter screen is blocked, a worker needs to detach the filter plate frame from the interior of the device for manual cleaning, and the process is tedious are solved.

The invention discloses blood component single sampling equipment capable of monitoring in real time in the field of blood treatment equipment. The equipment comprises a blood sampling module, a centrifugal separation module, a component collection module and an anticoagulant conveying module, and further integrates a multi-dimensional real-time monitoring system and a closed-loop self-adaptive regulation and control module. The multi-dimensional real-time monitoring system comprises an online micro-fluidic component detection unit, a physiological parameter monitoring unit and an equipment operation monitoring unit, can realize real-time online detection of blood component purity, cell activity and pollutant residue in the separation process, and synchronously monitors circulation physiological parameters of a blood donor and an equipment operation state at the same time; the closed-loop self-adaptive regulation and control module can dynamically adjust parameters such as the centrifugal rotating speed, the fluid pump speed and the anticoagulant ratio according to real-time monitoring data, and precise closed-loop control over the separation process is achieved. The quality stability of blood single-sampling components can be remarkably improved, meanwhile, the operation risk is greatly reduced, and the method is suitable for clinical blood component single-sampling and preparation scenes.

The purpose of the present invention is to provide a dialysis membrane capable of removing CPPs while suppressing a reduction in minerals and capable of being suitably used for blood processing including the adsorption of CPPs. The present invention pertains to a dialysis membrane comprising a hollow fiber membrane or a semipermeable membrane which is a flat membrane, wherein said dialysis membrane is used for blood processing including the adsorption of calciprotein particles which are complexes of calcium phosphate and proteins, and has a compound (A) in which a film-forming polymer constituting the semipermeable membrane has, in a portion other than terminals of a main chain, at least one electron-donating group selected from the group consisting of an amino group, a carboxy group, a phosphoric acid group, a phosphono group, a phosphino group, and a thiol group, and / or has, separately from the semipermeable membrane, at least one electron-donating group selected from the group consisting of an amino group, a carboxy group, a phosphoric acid group, a phosphono group, a phosphino group, and a thiol group.

The present invention relates to a device for preparing a medical fluid and / or for monitoring the preparation of a medical fluid, having a housing, a first control unit that controls the device in operation, and an access control unit that forms at least one interface between the device and the outside world, wherein the first control unit is configured to also control the device on a failure of the access control unit, and the control unit and the access control unit are each configured on a separate circuit board arranged in the housing and the access control unit furthermore has a communication unit for communication with the outside world and has a safety unit that is formed separately from the communication unit and that is configured to check every communication between the first control unit and the outside world over the interfaces and only to permit it after a determined technical safety assessment.

A valve for an extracorporeal blood treatment system includes a first body portion having a first passageway and a second passageway. The valve further includes a second body portion that is movable relative to the first body portion from a first valve position to a second valve position. The second body portion includes a third passageway and a fourth passageway. In the first valve position the first passageway and the third passageway are in fluid communication and define a first substantially linear flow path and the second passageway and the fourth passageway are in fluid communication and define a second substantially linear flow path. In the second valve position the first passageway and the fourth passageway are in fluid communication and define a third substantially linear flow path and the second passageway and the third passageway are in fluid communication and define a fourth substantially linear flow path.

A blood treatment apparatus (1) defines first and second flow circuits (C1, C2) separated by a dialyzer (20). The second flow circuit (C2) comprises return and withdrawal lines (24′, 24″) for connection to a vascular system of a subject during a treatment session. After the treatment session, a control system causes an operator to connect the second flow circuit (C2) to a first port (32) of a container (30), the apparatus (1) to perform a rinseback procedure, the operator to disconnect the return line (24′) from the vascular system and re-arrange the second flow circuit (C2) to define a closed loop, and the apparatus (1) to draw residual liquid from the closed loop into the first flow circuit (C1) through a dialyzer membrane (21). To facilitate drainage of the residual fluid with a conventional line set, the second flow circuit (C2) is connected to a second port (33) of the container (30) to include the container (30) in the closed loop, or the return and withdrawal lines (24′, 24″) are connected in fluid communication with the first port of the container (30) through a three-way manifold coupling unit.

Extracorporeal blood treatment device comprising a hydraulic system (B) with several lines (7, 9) for supplying dialysate for dialysis treatment and a control system (15) comprising at least one electrical component (17A, 17B, 17C), wherein the hydraulic system (B) has at least one port (11) for the inflow of a fluid into the extracorporeal blood treatment device, and the extracorporeal blood treatment device has a cooling device (19) for cooling the at least one electrical component (17A, 17B, 17C) of the control system (15), which has at least one liquid-coolable cooling element (21) which is in thermal contact with the at least one electrical component (17A, 17B, 17C) of the control system (15), wherein the cooling device (19) has at least one inlet (22A) which is in fluid communication with the port (11) for the inflow of a fluid.and has at least one outlet (22B) which is in fluid communication with a drain (10, 31), and wherein the cooling element is designed such that the liquid flows through the cooling element (21) and the thermal contact between the at least one electrical component (17A, 17B, 17C) of the control system (15) and the cooling element (21) is a contact contact, characterized in that the permeate supplied centrally to the device for extracorporeal blood treatment is used as the cooling liquid for the cooling element (21).

The invention discloses a control method of blood processing chips. The blood processing chips are loaded in a centrifugal machine; upper plasma and red blood cells are separated based on first centrifugation of blood, and normal saline enters a mixing area; the centrifugal machine stops working, the red blood cells sequentially enter a siphon flow channel and sequentially trigger second-time centrifugation and third-time centrifugation, the siphon flow channel is in an open state, and the red blood cells enter the mixing area from the red blood cell quantifying area; the red blood cells are layered with normal saline in the mixing area due to centrifugal action; carrying out fourth centrifugation, carrying out positive and negative rotation of the centrifugal machine, carrying out re-uniform mixing through oscillation, carrying out red blood cell resuspension, and carrying out multiple times of separation on the blood along the vertical direction; rotating the centrifugal tray by 90 degrees, standing for 3 minutes, and enabling the resuspension in the uniform mixing area to enter a capillary quantitative flow channel; the blood processing chip is matched with the detection card and judges the blood type, and the blood sample, the normal saline and the reverse red blood cells are located in the blood processing chip and are separated for multiple times in the blood processing chip.

The invention relates to a monitoring system for use in extracorporeal blood treatment, comprising a holding device designed for placement in the area of ​​a patient's venous access, a sensor device attached to the holding device and designed to detect a change in the position of a venous needle within the venous access and to generate a sensor signal representing the detected change in the position of the venous needle, a detection device connected to the sensor device and designed to determine a display signal depending on the sensor signal, and a display device connected to the detection device and designed to output the display signal optically and / or acoustically.

A graphical user interface of an extracorporeal blood treatment system may include one or more bar-shaped parameter adjustment elements. The bar-shaped parameter adjustment element may be used to determine and adjust one or more parameters associated with one or more processes performed by the extracorporeal blood treatment system. The bar parameter adjustment element may be scaled such that a midpoint of the bar parameter adjustment element represents a reference value.

The utility model discloses a duck blood product sterilizing device, which belongs to the technical field of duck blood processing equipment, and comprises two sterilizing boxes which are distributed in parallel, a water pump is arranged between the two sterilizing boxes, the water pump is connected with the two sterilizing boxes through a pipeline assembly, and a trolley is arranged on the inner sides of the sterilizing boxes. A plurality of vertically-distributed placement frames are installed on the inner side of the trolley, a thermometer is installed on the top of the sterilization box, a sealing cover is fixedly connected to the front face of the sterilization box through bolts, and an electric heater is arranged on the inner wall of the sterilization box. Through the arrangement of the water pump and the two sterilization boxes, the water pump can transfer high-temperature sterilization water on the inner sides of the two sterilization boxes through the pipeline assembly, when one sterilization box is used for sterilization, duck blood products are placed in the other sterilization box, and after sterilization is completed, the high-temperature sterilization water can be quickly transferred into the other sterilization box; and meanwhile, the working efficiency can be improved.

A blood collection tube comprising: a test tube comprising a vacuum facilitating an extraction of blood from a patient; the test tube further comprising a test tube septum comprising a mechanism having a space-occupying element enabling decreasing a slosh of the blood within the test tube; and wherein the test tube is compatible with conventional blood processing equipment.

An extracorporeal blood treatment apparatus 1 comprises a sampling circuit (27) having a by-pass line (28) connecting at least one supply line (9) to an effluent line (10) and a fluid pump assembly (29) active on the sampling circuit (27). The fluid pump assembly (29) is drivable between a first activated condition, in which the fluid pump assembly (29) causes one fluid crossing the fluid circuit (8) to flow through the by-pass line (28) from the at least one supply line (9) to the effluent line (10), and a second activated condition, in which the fluid pump assembly (29) causes the fluid crossing the fluid circuit (8) to flow through the by-pass line (28) from the effluent line (10) towards the at least one supply line (9). A concentrate sensor (30) is placed on the by-pass line (28) for monitoring the concentration of one substance detectable into the fluid crossing the fluid circuit (8). A control unit (100) is operatively connected to the concentration sensor (30) and to the fluid pump assembly (29) and is configured to drive the fluid pump assembly (29) either in the first activated condition or in the second activated condition and to receive signals from the concentrate sensor (30) and determine the concentration (Csup, Ceff) of the substance.

The invention relates to a device for extracorporeal blood treatment, comprising a fluid circuit, a heating device arranged within the fluid circuit and configured for heating a fluid circulating in the fluid circuit, at least one temperature sensor arranged within the fluid circuit and configured for detecting the actual temperature of the fluid, a control device configured for controlling the heating device as a function of a setpoint temperature of the fluid and the detected actual temperature, wherein an altitude sensor is provided and configured for detecting the altitude of the device, and the control device is configured for adjusting the setpoint temperature as a function of the detected altitude. The invention further relates to a method for operating such a device.

The invention discloses an inactivation cabinet, which comprises a cabinet body, and a plurality of suspension supports arranged side by side and used for suspending a plurality of independent initial blood bags respectively are arranged in the cabinet body from top to bottom in sequence; the plurality of flow controllers are arranged side by side and are respectively used for adjusting the flow speeds of the plurality of blood treatment pipelines; the plurality of ultraviolet lamp boxes are arranged side by side and are respectively used for irradiating the plurality of blood treatment illumination plates; the shaking table is used for uniformly shaking the blood collection bag, and the initial blood bag is sequentially connected with a blood treatment illumination plate and the blood collection bag through the blood treatment pipeline. According to the invention, accurate temperature and ultraviolet irradiation dose control is carried out on to-be-treated blood through a software control system, so that a safe and efficient pathogen inactivation effect is achieved.

A method that regulates supply of substituate in an extracorporeal blood treatment with an extracorporeal blood treatment apparatus comprising a dialyzer divided by a semipermeable membrane into a blood chamber and a dialyzing fluid chamber and a device for supplying substituate. An extracorporeal blood treatment apparatus that includes a device for regulating supply of substituate. Regulation of supply of substituate in the extracorporeal blood treatment takes place as a function of the rheological loading of the dialyzer. To regulate supply of substituate during extracorporeal blood treatment, rheological loading of the dialyzer is determined from transmembrane pressure on the dialyzer and flow resistance of the dialyzer and substituate rate is increased or reduced according to the loading. The selection of dialyzer parameters or blood parameters is therefore no longer necessary and the distinction between pre-dilution and post-dilution is also made obsolete.