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467 results about "Blood processing" patented technology

Blood Processing. The processing of blood into its various components must meet the very highest requirements to ensure clinical excellence. Because of the inherent variability of the source material and the absolute need for product purity, the demands placed on systems used to manufacture blood- and plasma-derived products are huge.

Tubing connector

Tubing connector having an inlet for a liquid and an outlet for the liquid as well a first tubing connector element and a second tubing connector element, wherein the inlet and the outlet. The connector comprises at least one first pressure measurement chamber for measuring the pressure of the liquid which is present in said first wherein the first chamber is fluidly arranged between the inlet and the first tubing connector element or between the outlet and the second tubing connector element. The measuring surface is arranged in an angled orientation w.r.t to pumping plane. Further, a blood treatment device is adapted to accommodate the tubing connector.
Owner:FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

Pump and pressure measurement arrangement

Pump and pressure measurement arrangement for a blood treatment device, comprising a pump, in particular a roller pump for pumping a liquid, a pump bed which is configured to accommodate a pump tubing, a first pressure measuring unit arranged to measure a pressure of the liquid. Further, Pump and pressure measurement arrangement provides an accommodation space for at least partially positioning a tubing connect connected to the pump tubing, wherein the tubing connector further comprises a pressure measuring chamber adapted to measure the pressure with the pressure measuring unit. Further, a blood treatment device is having the pump and pressure measurement arrangement and a tubing connector and a tubing set is fitting to the pump and pressure measurement arrangement.
Owner:FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

Tubing connector

Pump and pressure measurement arrangement for a blood treatment device, comprising a pump, in particular a roller pump for pumping a liquid, a pump bed which is configured to accommodate a pump tubing, a first pressure measuring unit arranged to measure a pressure of the liquid. Further, Pump and pressure measurement arrangement provides an accommodation space for at least partially positioning a tubing connect connected to the pump tubing, wherein the tubing connector further comprises a pressure measuring chamber adapted to measure the pressure with the pressure measuring unit. Further, a blood treatment device is having the pump and pressure measurement arrangement and a tubing connector and a tubing set is fitting to the pump and pressure measurement arrangement.
Owner:FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

Blood treatment systems and methods

Dialysis systems comprising actuators that cooperate to perform dialysis functions and sensors that cooperate to monitor dialysis functions are disclosed. According to one aspect, such a hemodialysis system comprises a user interface model layer, a therapy layer, below the user interface model layer, and a machine layer below the therapy layer. The user interface model layer is configured to manage the state of a graphical user interface and receive inputs from a graphical user interface. The therapy layer is configured to run state machines that generate therapy commands based at least in part on the inputs from the graphical user interface. The machine layer is configured to provide commands for the actuators based on the therapy commands.
Owner:DEKA PRODUCTS LP

Medical blood diversion and distribution device

The utility model discloses a medical blood flow guiding and distributing device which comprises a flow guiding plate and a distributing plate which are mutually buckled in a sealing mode, a cavity for containing blood is formed between the flow guiding plate and the distributing plate, the flow guiding plate is provided with an inlet, an outlet and an exhaust hole which are both communicated with the cavity, and the exhaust hole is provided with a waterproof breathable film. A plurality of distribution holes communicated with the cavity are formed in the distribution plate, a flow guide groove is formed in the side face, located in the cavity, of the flow guide plate, one end of the flow guide groove starts from the end, located in the cavity, of the inlet and outlet, and the other end of the flow guide groove extends in the direction away from the inlet and outlet. The utility model aims to provide the medical blood diversion and distribution device which can be mounted at a blood inlet and a blood outlet of a blood treatment device, so that the blood can obtain a better blood treatment effect, the speed of the blood flowing out of the treatment device is more uniform and stable, turbulence is not easy to generate, and hemolysis and thrombus are reduced.
Owner:AEROSPACE NEW LONG MARCH MEDICAL EQUIP (BEIJING) CO LTD +1

GelMA microneedle patch loaded with chromogenic gold nano bipyramid and preparation method of GelMA microneedle patch

The invention provides a GelMA microneedle patch loaded with chromogenic gold nano bipyramids and a preparation method thereof.The method comprises the steps that citric acid, chloroauric acid and a CTAC solution are mixed, then sodium borohydride is added, and a seed solution is obtained through stirring and standing; mixing chloroauric acid, silver nitrate, hydrochloric acid and CTAB (cetyltrimethyl ammonium bromide), and sequentially adding ascorbic acid and the seed solution to obtain a growth solution; carrying out centrifugation, morphology regulation and chemical etching purification to obtain a chromogenic gold nano bipyramid solution; the preparation method comprises the following steps: reacting gelatin with methacrylic anhydride in PBS, dialyzing and freeze-drying to obtain GelMA; dissolving GelMA in the gold nanoparticle bipyramid solution, and adding a photoinitiator LAP to obtain a mixed precursor solution; and the GelMA microneedle patch loaded with the gold nano bipyramid is prepared through mold casting, centrifugation, ultraviolet light crosslinking and drying demolding. The microneedle extraction and gold nano bipyramid color development integrated scheme is initiated, blood sampling is not needed, the dermis interstitial fluid is extracted in a minimally invasive mode through the microneedle, detection pain and trauma are reduced, the cross infection risk of blood treatment is avoided, and the microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle microneedle
Owner:JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE

Blood treatment systems and methods

Dialysis systems comprising actuators that cooperate to perform dialysis functions and sensors that cooperate to monitor dialysis functions are disclosed. According to one aspect, such a hemodialysis system comprises a user interface model layer, a therapy layer, below the user interface model layer, and a machine layer below the therapy layer. The user interface model layer is configured to manage the state of a graphical user interface and receive inputs from a graphical user interface. The therapy layer is configured to run state machines that generate therapy commands based at least in part on the inputs from the graphical user interface. The machine layer is configured to provide commands for the actuators based on the therapy commands.
Owner:DEKA PRODUCTS LP

Media supply arrangement for supplying a medical treatment device

The present disclosure pertains to a media supply arrangement for supplying a medical treatment device with a medium, in particular for supplying an extracorporeal blood treatment device with a dialysis medium, wherein an air conditioning device for air conditioning of a medical treatment device coupled to the media supply arrangement is provided.
Owner:FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

System and method for processing of whole blood into plasma products of different categorization

A blood processing device includes a pump system, a valve system, a separator and a controller configured to execute a plasma collection stage of a blood processing procedure by actuating the pump system and the valve system to convey blood from a blood source into the separator, actuating the separator to separate the blood into at least plasma and red blood cells, in a transfusion plasma collection step actuating the pump system and the valve system to convey a first volume of separated plasma out of the separator along a first flow path for transfusion plasma collection, and in a fractionation plasma collection step of the plasma collection stage, actuating the pump system and valve system to convey a second volume of the separated plasma out of the separator along a second flow path for fractionation plasma collection.
Owner:FENWAL INC

Blood treatment systems and methods

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and / or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and / or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and / or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.
Owner:DEKA PRODUCTS LP

System and method for connecting a concentrate container with a blood treatment device

The present invention refers to a system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, the invention refers to a container and blood treatment device to be used in a method according to the present invention.
Owner:FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

System and method for connecting a concentrate container with a blood treatment device

The present invention refers to a system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, the invention refers to a container and blood treatment device to be used in a method according to the present invention.
Owner:FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

Blood treatment equipment

The utility model belongs to the field of medical instruments, and particularly relates to blood treatment equipment. The blood treatment equipment comprises a blood treatment pond which is a sealed container and is provided with at least one first opening for plasma to enter and at least one second opening for blood to enter and exit; the plasma generator is used for generating plasma, and an outlet of the plasma generator is communicated with the blood treatment pond through the first opening; and the blood passage is communicated with the blood treatment tank through the second opening. According to the equipment disclosed by the invention, the plasma can be used for treating the blood, so that the oxidation resistance of the blood can be improved, and an equipment foundation is provided for the plasma to become a new health-care and treatment means.
Owner:BEIJING NEUROSURGICAL INST +1

Mixing device and mixing method for processing anti-fatigue deer blood peptide raw materials

The invention discloses a mixing device and a mixing method for anti-fatigue deer blood peptide raw material processing, and relates to the technical field of deer blood peptide mixing, the mixing device comprises a processing table, a control table is fixedly mounted on one side of the top surface of the processing table, and a frame is fixedly connected to the middle position of the top surface of the processing table; side seats are fixedly connected to the four corners of the top face of the machining table, first limiting wheels are rotationally connected to the side seats, a support is attached to the first limiting wheels, a plurality of sets of positioning seats are fixedly connected to the top face of the machining table, rotating rods are rotationally connected to the positioning seats, and arm plates are fixedly connected to the rotating rods. And the other end of the arm plate is rotationally connected with a second limiting wheel. The deer blood processing device is reasonable in structure, deer blood and ingredients are added into the processing box, the deer blood and the ingredients in the processing box are evenly mixed through the swing assembly, and after even mixing, mixed liquid is poured out by turning over the processing box.
Owner:TONGHUA CHENGCHENG PHARM CO LTD

Apparatus, systems and methods for storing, treating and / or processing blood and blood components

Apparatus, systems and methods are disclosed relating to certain aspects of blood processing, collecting or storing, including method and system for automated authentication, processing device with scanner, blood container with two dimensional barcode, blood collection containers, blood container label and related tracking method, integrated container system, and processing device with sterile connection device.
Owner:FENWAL INC

Peristaltic pump and rocker used therewith

A peristaltic pump, specifically for pumping fluid in an extracorporeal blood treatment apparatus, includes a pump housing that accommodates a rotor rotatable about a rotor axis and a squeeze element. The pump housing includes a support surface extending in a curved shape around the rotor axis and being radially spaced from the rotor. The support surface can support a tube segment that inserted radially between the rotor and support surface. The rotor supports the squeeze element via a rocker mounted on the rotor in a pivotable and cushioned manner. The rocker supports an insertion aid by which the tube segment can be pressed into the pump bed, and tube guide elements by which the tube segment is centrally alignable to the squeeze element. The rocker is made from high-strength stainless steel with high chemical resistance and manufactured by powder injection molding, such as metal injection molding.
Owner:B BRAUN AVITUM

Smanh-blended membranes for immobilizing functional molecules

PCT designated stage expiredWO2025021583A1MembranesSemi-permeable membranesPolymer sciencePyrrolidinones
The present disclosure relates to polysulfone, polyether-sulfone or polyarylethersulfone based membranes for use in extracorporeal blood treatment applications comprising a blend of (i) a polysulfone (PS), a polyethersulfone (PES) or a polyarylethersulfone (PAES); (ii) a polyvinylpyrrolidone (PVP); and (iii) a poly(styrene-alt-maleic anhydride)- copolymer which are configured for the immobilization of amine-bearing functional molecules on the surface of the membrane. The disclosure further relates to a method for producing the membranes and a filtration and / or diffusion device comprising the membrane.
Owner:GAMBRO LUNDIA AB +3

System comprising an extracorporeal blood treatment device and a heat exchanger

A system includes an extracorporeal blood treatment device and a heat exchanger for heat exchange between dialysate flowing from the extracorporeal blood treatment device and permeate to be supplied to the extracorporeal blood treatment device. The extracorporeal blood treatment device and the heat exchanger are configured as separate devices.
Owner:B BRAUN AVITUM

System and method for processing of whole blood into plasma products of different categorization

A blood processing device includes a pump system, a valve system, a separator and a controller configured to execute a plasma collection stage of a blood processing procedure by actuating the pump system and the valve system to convey blood from a blood source into the separator, actuating the separator to separate the blood into at least plasma and red blood cells, in a transfusion plasma collection step actuating the pump system and the valve system to convey a first volume of separated plasma out of the separator along a first flow path for transfusion plasma collection, and in a fractionation plasma collection step of the plasma collection stage, actuating the pump system and valve system to convey a second volume of the separated plasma out of the separator along a second flow path for fractionation plasma collection.
Owner:FENWAL INC

Blood purifier

A blood purifier includes a porous molded body; exhibits an excellent blood compatibility wherein platelet adherence is inhibited and exhibits a good cytokine adsorption capacity and a low pressure loss before and after blood treatment; and can be safely used. A blood purifier includes a main vessel and a porous molded body housed in the main vessel. The porous molded body contains a hydrophobic polymer and a hydrophilic polymer. The amount of low-melting-point water per 1 g of dry weight of the porous molded body is 0.12 g to 2.00 g. The contact change ratio for the porous molded body is 0% to 0.2%. The ratio L / D is 1.00 to 2.30 where, for the region taken up by the porous molded body in the main vessel, L is the length in the flow direction and D is the circle-equivalent diameter of the cross section in the direction perpendicular to the flow direction.
Owner:ASAHI KASEI MEDICAL CO LTD

Air elimination device for extracorporeal blood treatment

A blood circulation system for an extracorporeal blood treatment machine includes: an arterial circulation section; a venous circulation section; a dynamic bubble trap; and an air separator. The blood circulation system conducts blood, during the operation of a blood pump of the extracorporeal blood treatment machine, from a patient to a dialysis unit and from the dialysis unit to the patient. The blood circulation system also includes a recirculation or branch line connected to the bubble trap in order to return part of the blood that flows into the bubble trap into the blood circulation system, upstream of the bubble trap. An extracorporeal blood treatment machine includes the blood circulation system.
Owner:B BRAUN AVITUM

Blood treatment device with ambient temperature variation compensation

The present invention relates to a control or regulation device (150) configured to control or regulate the operation of a blood treatment device (100) for treating a patient during a blood treatment period wherein the blood treatment device (100) is connected to an extracorporeal blood circuit (300) and to a blood treatment device, such as a dialyzer (303) or a blood filter. The blood treatment apparatus (100) further comprises a dialysis liquid inlet line (104) and a dialysis liquid outlet line (102), a heating device (162) for heating the dialysis liquid, and one or more temperature sensors (165a, 165b) wherein at least a first temperature sensor (165a) is arranged downstream of the blood treatment device and / or downstream of the dialysis liquid inlet line (104) and at least a second temperature sensor (165b) is arranged downstream of the dialysis liquid outlet line (102). A first temperature value (T1) of a first liquid flowing prior to the dialysis liquid inlet line (104) is determined for determining a second temperature value (T2) of a second liquid flowing prior to the dialysis liquid inlet line (104). Here, the control or regulation device (150) is configured to increase or set the temperature of the dialysis liquid using the heating device (162) on the basis of a first temperature value (T1) determined by the first temperature sensor (165a).
Owner:FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

Bulb tube current feedback and synchronous irradiation control system in blood irradiator

The invention provides a bulb tube current feedback and synchronous irradiation control system in a blood irradiator, and belongs to the technical field of medical irradiation equipment. Comprising a current acquisition module used for processing target blood by a target blood irradiator and outputting a current signal, a signal conditioning module used for carrying out filtering, level conversion and electromagnetic noise suppression processing on the output current signal, and a current control module. An STM32 microcontroller adopts an incremental proportional control algorithm to dynamically adjust output gain of a high-voltage generator, a synchronous irradiation control module, generation of a synchronous control signal and operation of a management module, a target blood irradiator is controlled to enter a low-power-consumption mode in a non-irradiation stage, and the current of a bulb tube is collected in real time and is processed, so that the current of the high-voltage generator is obtained. High precision and stability of the current signal are ensured, a synchronous control signal is generated according to the current signal after signal conditioning and the irradiation process state, and coordination control of sample rotation and radiation output is realized.
Owner:WENZHOU PEOPLES HOSPITAL

Blood treatment device

The present invention relates to a blood treatment device, comprising a first hemofilter configured to increase a hemoconcentration of blood; a second hemofilter arranged fluidically downstream of the first hemofilter and configured to remove toxins from the blood into an albumin containing dialysate; a flow regulator arranged in a fluid line conducting fluid out of the first hemofilter; a flow sensor configured to measure a flow in a fluid line conducting dialysate into the second hemofilter and a flow in a fluid line conducting dialysate out of the second hemofilter; and a control unit configured to con- trol the flow regulator depending on the measurement data of the flow sensor to set an outflow of dialysate out of the first hemofilter.
Owner:FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

System and method for extracorporeal blood treatment

The present application relates to an extracorporeal blood treatment system (50) for treating a subject, the system comprising: an extracorporeal blood circuit (52); a dialysate fluid circuit (54); the extracorporeal blood circuit and the dialysate fluid circuit being separated by a membrane (56) of a filtration unit (58); at least one blood pump (60) for controlling the flow of blood through the blood circuit; at least one dialysate fluid pump (62) for controlling the flow of dialysate fluid through the dialysate fluid circuit (54); a system computing unit (64) operatively connected to the blood pump and to the dialysate fluid pump, the system computing unit having at least one input; wherein the system computing unit is adapted to receive a desired blood concentration of glutamine GLN b , to receive a desired blood concentration of glucose GLUCOSE b , and to receive a desired blood concentration of ketone bodies KETONE b ; the system computing unit being adapted to control the blood pump and the dialysate fluid pump such that an actual concentration value of glutamine GLN a is driven to approach GLN b , and an actual concentration value of glucose GLUCOSE a is driven to approach D b , and an actual concentration value of ketone bodies is driven to approach KETONE a . The present application relates to a treatment device for use in an extracorporeal blood treatment system, a method for treating cancer using the system, a controller for controlling the method and a dialysis liquid suitable for use in the method.
Owner:GAMBRO LUNDIA AB

Contrast agent filtering device for coronary artery surgery and use method of contrast agent filtering device

The invention discloses a contrast agent filtering device for coronary surgery and a using method thereof, the device is integrally in a plastic bag shape and comprises a filtering bag body, the bottom of the filtering bag body is provided with a transfusion connector and a blood transfusion connector which are provided with sealing covers, and an inner opening is sleeved with a filter screen support with a filter screen; the filter bag body is divided into a filter area and an adsorption particle storage area through a middle seal, a flushing connector and a hanging hole are arranged at the top, and the filter bag body can be matched with a vibration disc for use. The use method comprises the steps that blood containing a contrast agent is extracted and input into the filtering area, the middle seal is opened through pressing, the blood makes full contact with the adsorption particles through vibration or manual extrusion so as to adsorb the contrast agent, then the filtered blood is infused back, and residual plasma can be infused back after being diluted with normal saline. The device is simple in structure, low in cost and easy and convenient to operate, the filtering effect is improved by 30% compared with the prior art, the adsorption rate reaches 75%-85%, contrast agents in blood can be effectively removed, damage to the kidney of a patient is reduced, and the device is particularly suitable for blood treatment of the patient after coronary angiography.
Owner:BEIJING ZKSK TECH

Filtering device for animal slaughtering blood treatment and treatment method

The invention provides a filtering device for animal slaughtering blood treatment and a treatment method, and relates to the field of animal slaughtering blood treatment.The filtering device comprises a filtering assembly, the filtering assembly is composed of a flow channel mechanism and a control mechanism, the flow channel mechanism is of a double-working-flow-channel design, different flow channel sets can be switched for use through the control mechanism, and the flow channel sets are connected with the control mechanism; therefore, the animal slaughtering blood can be filtered, the filter frame and a filter screen in the filter frame can be washed and cleaned on the premise that the filter frame is not detached, the blood filtering precision and efficiency are effectively guaranteed, the limitation that traditional equipment needs to be shut down to be detached and cleaned is broken through, and the practicability is high. The problems that a filter plate frame of an existing slaughter blood filter device is arranged in the filter device, a backflushing structure is not arranged, and after a filter screen is blocked, a worker needs to detach the filter plate frame from the interior of the device for manual cleaning, and the process is tedious are solved.
Owner:NINGXIA RUNTAI BIOTECHNOLOGY CO LTD

Blood component single sampling equipment capable of monitoring in real time

The invention discloses blood component single sampling equipment capable of monitoring in real time in the field of blood treatment equipment. The equipment comprises a blood sampling module, a centrifugal separation module, a component collection module and an anticoagulant conveying module, and further integrates a multi-dimensional real-time monitoring system and a closed-loop self-adaptive regulation and control module. The multi-dimensional real-time monitoring system comprises an online micro-fluidic component detection unit, a physiological parameter monitoring unit and an equipment operation monitoring unit, can realize real-time online detection of blood component purity, cell activity and pollutant residue in the separation process, and synchronously monitors circulation physiological parameters of a blood donor and an equipment operation state at the same time; the closed-loop self-adaptive regulation and control module can dynamically adjust parameters such as the centrifugal rotating speed, the fluid pump speed and the anticoagulant ratio according to real-time monitoring data, and precise closed-loop control over the separation process is achieved. The quality stability of blood single-sampling components can be remarkably improved, meanwhile, the operation risk is greatly reduced, and the method is suitable for clinical blood component single-sampling and preparation scenes.
Owner:CHONGQING TRADITIONAL CHINESE MEDICINE HOSPITAL

Blood treatment systems and methods

A pumping system comprising: a pneumatically driven diaphragm pump comprising: a rigid chamber wall; a rigid limit structure; a flexible diaphragm attached to the rigid chamber wall and interposed between the rigid chamber wall and the rigid limit structure, such that the flexible diaphragm and rigid chamber wall together define a pumping chamber and the flexible diaphragm and the rigid limit structure together define an actuation chamber; an inlet in the rigid chamber wall for allowing liquid to enter the pumping chamber; and an outlet in the rigid chamber wall for allowing liquid to exit the pumping chamber; an actuation system that alternately provides either a positive or a negative pressure to the actuation chamber; wherein the actuation system includes: a first reservoir held at a positive pressure; a second reservoir held at a negative pressure; a valving mechanism selectively connecting the actuation chamber to one of the first and second reservoirs to control a pressure in the actuation chamber; and an actuation chamber pressure transducer for measuring a pressure of the actuation chamber; and a controller that receives pressure information from the actuation chamber pressure transducer and in a first time period controls the valving mechanism to complete at least one full stroke of the flexible diaphragm by moving the flexible diaphragm between a position touching the rigid limit structure and a position touching the rigid chamber wall, the controller being configured to record a full stroke value for a stroke parameter corresponding to each at least one full stroke, and in a subsequent time period to control the valving mechanism to complete partial strokes of the flexible diaphragm by controlling the stroke parameter to be a fraction of the full stroke value.
Owner:DEKA PRODUCTS LP

Dialysis membrane, method for manufacturing same, and method for using same

The purpose of the present invention is to provide a dialysis membrane capable of removing CPPs while suppressing a reduction in minerals and capable of being suitably used for blood processing including the adsorption of CPPs. The present invention pertains to a dialysis membrane comprising a hollow fiber membrane or a semipermeable membrane which is a flat membrane, wherein said dialysis membrane is used for blood processing including the adsorption of calciprotein particles which are complexes of calcium phosphate and proteins, and has a compound (A) in which a film-forming polymer constituting the semipermeable membrane has, in a portion other than terminals of a main chain, at least one electron-donating group selected from the group consisting of an amino group, a carboxy group, a phosphoric acid group, a phosphono group, a phosphino group, and a thiol group, and / or has, separately from the semipermeable membrane, at least one electron-donating group selected from the group consisting of an amino group, a carboxy group, a phosphoric acid group, a phosphono group, a phosphino group, and a thiol group.
Owner:KANEKA CORP +1