1419results about "Dialysis systems" patented technology

The invention relates to the technical field of medical prediction, in particular to a digital twinborn prediction method for patient lung protective ventilation supported by ECMO, which comprises the following steps: extracting flow velocity change and jump points under the support of ECMO, constructing a ventilation fluctuation trend map, identifying fluctuation sections by combining compliance and pressure value ratio, delimiting lung partitions and analyzing oxygenation ratio trend. And generating an oxygenation capability classification graph, sequencing ventilation path effects, and outputting a pulmonary protective ventilation digital twinborn prediction scheme. According to the method, dynamic response mapping of ventilation behaviors is established on the basis of timing sequence changes of breathing flow velocity jump characteristics and compliance pressure value ratios, the lung regional ventilation state is accurately recognized, lung function zoning division is achieved by combining oxygenation ratio waveform classification, ventilation path utility sorting is completed through oxygenation descending characteristics under path coverage, and the lung function evaluation accuracy is improved. And a path state prediction sequence is constructed by fusing the change relationship between the tensile stress and the ventilation pressure, so that the dynamic adaptability of the ventilation strategy to the lung mechanics and oxygenation state and the region matching precision are improved.

The invention relates to the technical field of deep learning, in particular to a dialysis hypotension risk prediction system and method based on deep learning, and the system comprises a multi-point signal collection module, a signal processing module, a multi-scale causal expansion convolutional network prediction module, an osmotic pressure correction module and a dialysis plan automatic adjustment module. The method comprises the following steps: synchronously collecting physiological signals of a patient through a finger tip photoelectric volume sensor and a radial artery piezoelectric sensor array, carrying out band-pass filtering and morphological refinement processing on the signals, extracting features, and calculating pulse wave conduction time and a change rate thereof; inputting the characteristic parameters into a multi-scale causal expansion convolutional network to predict the hypotension risk in dialysis; dynamically correcting the prediction result according to electrolyte monitoring data; based on the corrected risk, a hierarchical response strategy is adopted to automatically adjust dialysis parameters, a multi-scale causal expansion convolutional network is adopted to capture physiological parameter changes on different time scales at the same time, and high-precision prediction of hypotension is achieved.

The invention relates to the technical field of hemodialysis, and discloses a hemodialysis ultrafiltration amount adjusting system based on multi-parameter self-adaptive control, which is used for solving the problem of insufficient prediction and prevention precision of a hemodialysis induced hypotension risk in a traditional system. According to the method, firstly, multi-parameter physiological data of the blood volume, the blood pressure and the ion concentration are synchronously collected in the whole dialysis process, then a physiological state data set is constructed through unified standardization and correlation matching, related change modes of the blood volume and the blood pressure are extracted, and ion deviation is superposed to form comprehensive risk characteristics; the risk characteristics are compared with a preset threshold value through trend analysis, the weight of each risk component is adjusted in a self-adaptive mode, a hypotension risk trend index is generated, the ultrafiltration rate is dynamically adjusted in a graded mode according to the indexes, the indexes are coupled with a real-time physiological data feedback closed loop, and therefore the prediction precision and the regulation and control refinement level of dialysis-induced hypotension are improved.

The double-cavity cannula comprises a cannula body, the cannula body comprises an outer tube with an opening in the upper end and an inner tube coaxial with the outer tube, the upper end of the outer wall of the cannula body is provided with a connecting part communicated with the cannula body in a matched mode, a plurality of blood guide side holes are formed in the lower portion of the outer wall of the outer tube, and the opening in the lower end of the inner tube is communicated with a blood guide hopper. A blood return assembly is arranged on the inner wall of the outer tube and above the blood guide hopper, a blood flow guide cover is arranged on the inner wall of a blood return opening of the blood return assembly in a matched mode, a balloon capable of being filled and emptied is arranged on the outer wall of the outer tube and above the blood guide side hole, a filling valve is arranged on one side of the outer wall of the connecting part, and the filling valve is communicated with the balloon through a filling pipeline. When blood is guided, the conditions of local blood vessel wall adsorption and unsmooth blood guiding cannot be easily caused by the design of the blood guiding side holes, and the injection effect, blood turbulence and hemolysis risk increase cannot occur during blood return.

The invention provides a functional nanofiber material as well as a preparation method and application thereof, and the preparation method comprises the following steps: (1) adding raw materials into water to form an electrostatic spinning solution; performing electrostatic spinning to obtain a nanofiber membrane; (2) cross-linking the nanofiber membrane in an organic solvent under the catalysis of acid to obtain a cross-linked nanofiber membrane; and (3) carrying out grafting reaction on the cross-linked nanofiber membrane in a polyamine cross-linking agent, and then reacting with a sulfur-containing reagent to obtain the functional nanofiber material, the functionalized nanofiber material prepared by the preparation method disclosed by the invention combines good biocompatibility of polyvinyl alcohol, high specific surface area and high porosity of nanofiber and a synergistic adsorption effect of the polyamine cross-linking agent and cysteine, and has the advantages of large adsorption capacity, high adsorption rate, strong selectivity, good biocompatibility, stable structure and the like; the heavy metal ions in the plasma can be efficiently and safely removed, and a plurality of defects of the existing adsorption material are overcome.

To enable water removal control that can respond to various patients and the conditions of each patient, and that can perform efficient water removal treatment while reducing the burden on the patient. [Solution] The device has a memory unit that stores the water removal achievement rate at a specified elapsed time during blood purification treatment, and a calculation unit that sets a water removal profile in which the water removal rate gradually decreases from the start to the end of blood purification treatment, and the calculation unit is equipped with a water removal rate determination unit that determines the water removal rate for a specified time at a specified elapsed time based on the water removal achievement rate.

The present invention relates to systems and methods for optimizing plasma collection volume. A plasma withdrawal system and a method for operating a plasma withdrawal system are provided by which the volume / weight of the anticoagulated plasma collected is optimized. In one example, a nomogram is provided that utilizes the donor hematocrit to calculate the volume / weight of raw plasma within a plasma product having a maximum volume allowed by the FDA nomogram. In a plasma withdrawal process having multiple collection phases followed by a reinfusion cycle in which concentrated red blood cells are returned to the donor, the volume of plasma product to be collected is calculated prior to the start of each collection cycle to account for the increasing hematocrit of the donor, resulting in a greater total volume of plasma product to be collected during the plasma withdrawal process.

The invention relates to the technical field of medical equipment, in particular to an edge calculation respirator system and method for adaptive ventilation control, and the system comprises a respirator end which is provided with an edge calculation module and a local control model; the edge calculation module is used for collecting multi-modal physiological parameters of a patient and performing data preprocessing on the multi-modal physiological parameters of the patient to generate a multi-dimensional feature vector; the local control model carries out real-time self-adaptive adjustment on ventilation parameters of the breathing machine based on the multi-modal physiological parameters of the patient and the baseline characteristics of the patient; the cloud server is in communication connection with the respirator end and is configured with a global optimization model; and the cloud server receives historical ventilation data of the respirator end, and the global optimization model performs training based on the historical ventilation data to generate a personalized ventilation strategy, and issues the personalized ventilation strategy to the respirator end for correcting adjustment of the local control model. According to the invention, low latency and high reliability of bedside control are guaranteed through a side cloud collaborative architecture.

The invention discloses a medicine adding device used in cooperation with a hemodialysis machine and a using method of the medicine adding device. The medicine adding device used in cooperation with the hemodialysis machine comprises a blood pipeline and a medicine adding device, the first medicine adding assembly comprises a bin body, a first medicine liquid guide pipe and a flow control assembly. During use, medicine entering the bin body can be slowly injected into the blood pipeline through the first medicine liquid guide pipe by adjusting the flow control assembly. Under an original conventional medicine adding mode, medicine injected into blood at a time through an injector can be slowly injected into the blood when the first medicine adding assembly of the medicine adding device is adopted for medicine adding, so that the medicine can flow into the blood slowly and more dispersedly, is more fully and uniformly mixed with the blood and then flows back into the body of a patient along with the blood successively, and the medicine adding effect is good. A better treatment effect is achieved; and meanwhile, for the medicament needing to be slowly injected, medical personnel do not need to slowly push the piston of the injector to slowly move to inject the medicament, so that the operation difficulty of slowly injecting the medicament is reduced.

The invention relates to the technical field of medical equipment, and discloses an intelligent temperature control and flow control system for hemodialysis, which comprises a dialysis pipeline shunting shell; the two main pipelines are arranged in the dialysis pipeline shunting shell, and a plurality of slave pipelines are arranged between the two main pipelines; when the flow rate of the liquid is low, the slave pipeline is far away from the heating component, the temperature of the liquid cannot rise too fast under the condition that the flow rate is low, the knob part can move to the slave pipeline when controlling the valve component to increase the flow rate of the liquid, and the slave pipeline moves close to the heating component. The distance between the auxiliary pipeline and the temperature rising component is reduced, when the flow rate of liquid with large flow is high, the auxiliary pipeline gets close to the temperature rising component, heat generated by the temperature rising component can be better received by the auxiliary pipeline and conducted to the liquid, and the flow adjusting system and the temperature control system can cooperate to achieve the purpose that the flow adjusting system and the temperature control system work together. A preset temperature value can be provided for the dialysis liquid all the time when the flow is increased or decreased.

The invention relates to the crossing field of computer technology and edge calculation, and discloses a blood purification equipment real-time control method based on edge calculation. According to the method, multi-modal real-time physiological parameters, historical dialysis data and a current treatment target are fused through a local edge calculation unit, an individualized body fluid dynamic response prediction model is constructed, and an ultrafiltration rate instruction is optimized and generated within a millisecond level; the system comprises a multi-mode sensor array, a historical data storage module, a task planning interface, an edge computing unit and an ultrafiltration pump controller. According to the application, the hemodynamic state is accurately maintained, the risk of hypotension is remarkably reduced, and the treatment safety and individualization level are improved.

A water treatment plant or system for the production of permeate includes a reverse osmosis stage and a permeate stage. The reverse osmosis stage can include a piping system having a supply line for process input water, a reverse osmosis pump, and a reverse osmosis tank. The reverse osmosis tank has an inlet for process input water coming from the reverse osmosis pump, a membrane, and an outlet for permeate. The permeate stage, which can have a line system forming a circuit, can include a permeate tank, a permeate pump, and a tapping point for connecting at least one consumer or user of permeate. The reverse osmosis stage and the permeate stage can be connected to one another via a connecting line in such a way that the reverse osmosis stage feeds the permeate stage with permeate. The circuit of the permeate stage can include a sterile filter.

The invention discloses a dialysate supply device for hemodialysis, which comprises a tank body, a partition plate, a material storage tank, a liquid storage box, a stirring rod and a power mechanism, and is provided with a feeding mechanism, a liquid discharge mechanism and a supply device, the feeding mechanism performs lifting reciprocating motion through a first conical block and a second conical block which are driven by a cam; quantitative closed feeding of dialysis dry powder is achieved, the problem that a traditional blade cuts a dry powder bag to cause scrap pollution is solved, a liquid discharging mechanism adopts a double-column-shaped shell to be matched with a piston plate and a one-way valve and is in linkage with a feeding mechanism, medicine liquid is synchronously and quantitatively extracted, and a supply device utilizes a floating block to ascend and descend along with the liquid level, and a sealing block is driven to be opened and closed through an adjusting rod. According to the automatic feeding device for the dialysis dry powder, the dialysis dry powder is accurately metered, mixed and fed, and the preparation quality of the dialysis liquid and the clinical use safety are improved.

The invention relates to the technical field of dialysis process monitoring, in particular to a dialysis scheme self-adaptive interface system and method based on individual parameters of a patient, according to physiological state data and blood purification process data of the patient, the blood purification abnormal condition of the patient under the current dialysis scheme is analyzed; the acute complication risk of the patient under the current dialysis scheme is predicted; in combination with the physiological state data and the dialysis strategy data of the patient, analyzing the re-adaptation abnormal risk of purified blood and the body of the patient after dialysis under the current dialysis scheme; the assessment of the dialysis treatment safety risk of the patient under the current dialysis scheme is realized; therefore, self-adaptive adjustment and early warning can be carried out on the dialysis scheme of the patient. The reliability of dialysis treatment is improved, the treatment safety of a patient is guaranteed, and the occurrence risk of acute adverse events is reduced.

The invention is applicable to the technical field of hemodialyzers, and provides a hollow fiber membrane hemodialyzer with a gradient aperture structure, which comprises a shell, a hollow fiber membrane bundle packaged in the shell, an end cover and a sealing component, the hollow fiber membrane bundle is composed of a plurality of gradient aperture hollow fiber membranes; the hollow fiber membrane is of a two-way gradient aperture structure along the membrane thickness direction; a compact screening layer and a loose transition layer are sequentially arranged on the inner wall of the hollow fiber membrane; a loose diffusion layer and a compact protective layer are sequentially arranged on the outer side of the hollow fiber membrane; the pore diameter of the compact protective layer is not greater than 30nm; the porosity of the hollow fiber membrane is synchronously and progressively increased along with the aperture gradient, the porosity range is 40%-80%, the dialyzer has the characteristics of bidirectional gradient aperture optimization design, gradient functional coating protection, modular adaptation, special-shaped section synergy and the like, and the technical problems that an existing dialyzer is incomplete in toxin removal, insufficient in safety and the like are solved.

Perfusion systems and methods are provided for enhancing perfusion to the vasculature of a patient suffering from reduced blood flow. For example, the system can increase peripheral blood flow to reduce limb ischemia, in which an extracorporeal pump having a controller, and catheter / tubing set, employed alone or in conjunction with an interventional or circulatory assist device, withdraws blood from a patient's vasculature and reintroduces that blood at another location within the patient's vasculature at a controlled local pressure or flow rate, without interfering with operation of the interventional or circulatory assist device or surgical intervention.

The invention relates to the technical field of blood purification, and particularly discloses an integrated blood purification pipeline consumable device which comprises a main body bracket, and an artery pipeline assembly, a dialysis filter, a vein pipeline assembly, a pre-flushing piston assembly, a liquid inlet tank assembly and a liquid outlet tank assembly which are mounted on the main body bracket. The key core problem solved by the invention is to integrate treatment consumable pipelines and integrate a plurality of auxiliary function modules, so that the operation convenience of medical staff is greatly improved on the premise of ensuring treatment; by configuring an automatic pre-flushing function, a heparin injection function, a quantitative system and the like, the operation process of ultralight portable blood purification equipment matched with the device can be simplified, the size and the weight of the equipment are reduced, and the equipment is suitable for wider and more complex application environments; the method can be used for early treatment of severe wounded persons in modern wars, emergency supplement of conventional dialysis treatment patients, disaster relief without traditional dialysis conditions, self-treatment of patients in emergencies and the like, and has wide application prospect and practical value.

The utility model relates to the technical field of stretchers, in particular to a wounded transferring life monitoring and supporting system based on a stretcher. The fixing device is detachably installed on the stretcher device, and the monitoring devices and the life supporting devices are detachably fixed to the fixing device. The stretcher equipment transfers the wounded; the monitoring devices monitor vital signs of the wounded, acquire vital sign data and display the vital sign data, and the electronic device receives the vital sign data transmitted by the monitoring devices, identifies the vital sign data and outputs prompt information when the vital sign data are abnormal. The problem that effective life monitoring and supporting means are lacked in the transferring process of the stretcher wounded is solved. And medical workers do not need to carry equipment to carry out life monitoring and support on the wounded, so that human resources of the medical workers are saved. In addition, medical workers do not need to check the vital sign data monitored by the monitoring equipment in real time, and then human resources of the medical workers are further saved.

The utility model discloses a blood extracorporeal circulation device, which belongs to the technical field of blood extracorporeal circulation equipment and comprises an inner tube and an outer tube, the inner tube and the outer tube are integrally nested, one end of the outer tube is connected with an air inlet tube, the air inlet tube is communicated with oxygen inlet equipment, and the other end of the outer tube is connected with an air outlet tube. A temperature changer and a flow speed controller are connected between one end, far away from the air outlet end, of the outer pipe and the oxygen inlet equipment; one end of the inner tube is a liquid inlet end for transporting blood, the other end of a blood inlet of the inner tube is a liquid outlet end, and the liquid outlet end is connected with a temperature sensor, an oxygen saturation sensor, a blood pump and a microembolus filter; the part, in the outer pipe, of the inner pipe is made of a gas exchange membrane material, and the liquid inlet end of the inner pipe is opposite to the gas inlet pipe of the outer pipe. The blood temperature rising process is safer, meanwhile, in the blood temperature rising process, the oxygen saturation index in the blood can be directly adjusted, the blood oxygen value is simple, convenient and controllable on the basis of convenient temperature rising, temperature control and oxygen saturation of in-vitro blood circulation are carried out at the same time, and operation is easy and safe.

The invention discloses an intelligent disturbance and analysis method and system for hemodialysis data, and relates to the field of hemodialysis data analys.The intelligent disturbance and analysis method comprises the steps that in the hemodialysis process, disturbance signals are superposed through a blood input pump, so that blood parameters input into a dialyzer generate preset configuration changes, and therefore input disturbance signals are formed; in the disturbance applying period, blood parameters of the blood output end of the dialyzer are collected in real time, and corresponding output response signals are formed; performing cross-correlation analysis on the input disturbance signal and the output response signal, and calculating a time delay parameter between the input disturbance signal and the output response signal; periodically and repeatedly detecting, carrying out regression analysis on the time delay parameter, and when the time delay parameter is continuously increased along with time, judging that the dialyzer has a blockage trend and outputting early warning information. According to the method, early detection on the dialyzer blockage is realized through the dynamic time-lag characteristics under the condition of not increasing a sensor, and the safety of a hemodialysis system is improved.

A medical drain bag includes a main body that defines a reservoir. The main body is configured to hold a liquid within the reservoir. The medical drain bag includes a plurality of ports that are each in fluid communication with the reservoir. The plurality of ports include an input port configured to be coupled to a catheter and receive the liquid through the catheter, a syringe port that is configured to allow the liquid to flow from the reservoir and to a syringe, and a sample port that is coupled to an imaging slide and is configured to allow the liquid to flow from the reservoir and to the imaging slide. The imaging slide includes a channel configured to receive the liquid, an imaging window that at least partially defines the channel, and an inlet that is coupled to the sample port.

To provide a blood purification device that can accurately determine whether a venipuncture has been performed correctly in a patient. [Solution] The blood purification device 1 comprises a blood purifier 3 capable of purifying blood, a blood circuit 2 having an arterial blood circuit 21 and a venous blood circuit 22, an impedance measuring unit 5 having an oscillator 53 that applies an AC voltage between an arterial electrode 51 provided on the arterial blood circuit 21 and a venous electrode 52 provided on the venous blood circuit 22, and capable of measuring the frequency characteristics of the impedance between the arterial electrode 51 and the venous electrode 52, and a puncture determination unit 72 that determines whether the patient has been punctured normally based on the measured impedance frequency characteristics, and further comprises a voltage control unit 70 that controls the amplitude of the AC voltage applied by the oscillator 53 so that the amplitude of the AC current that flows when the AC voltage is applied from the oscillator 53 is greater than or equal to a preset lower threshold.

The present invention relates to a method and apparatus for exchanging gas between two exchange media using an exchange chamber (1) disposed within the housing of an exchange unit, wherein the exchange chamber (1) is divided into two chamber regions by at least one membrane (2), in which the first side of the membrane (2) is in contact with the first exchange medium in the first chamber region, and the second side of the membrane (2) is in contact with the second gaseous exchange medium in the second chamber region, the first chamber region having a connection for the first exchange medium, the first chamber region being incorporated into a first conduit (3) by this connection, and the first exchange medium being passed through the first chamber region using the first conduit. The second chamber region has a connection for a second gaseous exchange medium, and by this connection the second chamber region is incorporated into the second conduit (4), and the second exchange medium can be guided through the second chamber region using the second conduit, and the gas to be exchanged can be transported across the membrane (2) by diffusion, and the apparatus has a pressure generator (9a), and the pressure generator (9a) can be used to generate a pressure difference of at least 10 mmHg of the second exchange medium relative to the ambient atmospheric pressure in the second chamber region, and at least one membrane (2) is permeable to diffusion with respect to the gas to be exchanged, but impermeable to convection.

The invention relates to the technical field of liquid level detection, in particular to a medical liquid level sensor which comprises a reducer pipe fixedly connected and communicated with a liquid conveying pipeline, the reducer pipe is provided with a plurality of parts with different pipe diameters from top to bottom, and the pipe diameters of the reducer pipe are sequentially reduced from top to bottom. A sensor for detecting the liquid level is arranged at each part with different pipe diameters of the reducer pipe, so that quick response or precise detection of the liquid level can be carried out by utilizing different capacitance changes caused by liquid level changes in different pipe diameters.

Disposable set for an extracorporeal blood treatment apparatus including a blood circuit comprising a filtration unit, a blood withdrawal line including a blood pump tract configured to be engaged by a blood pump, a blood return line, and an infusion line extending between a first end connected to the blood withdrawal line upstream the blood pump tract, and a second end for connection to an infusion substance source: the blood pump tract is interposed between the filtration unit and the first end of the infusion line. The disposable set further comprises a pressure damper arranged towards or at the first end of the infusion line, the pressure damper being configured to prevent, or reduce an amount of, the access negative pressure to extend in the infusion line upstream the pressure damper.

A control device (10) and method for determining the permeability state of a forward osmosis (FO) membrane (2c) of a FO device (2) in a dialysate generator (1). The FO membrane (2c) separates a feed side (2a) and a draw side (2b) of the FO device (2). The FO device (2) has a feed inlet port (E) in fluid communication with the feed side (2a). in ) and the feed outlet port (E out ) and a draw inlet port (L ) in fluid communication with the draw side (2b). in ) and draw outlet port (L out ). The method includes providing (S1) a flow of pure water to the feed side (2a) and providing (S2) a flow of pure water to the draw side (2b). The method further includes monitoring (s3) one or more pressures indicative of a transmembrane pressure, TMP, between the feed side (2a) and the draw side (2b). The method further includes stopping (S4) the flow through one of the ports such that the TMP is maintained constant and of a non-zero magnitude, controlling (S5) the flow to or from one of the feed side (2a) and the draw side (2b) with the flow stopped based on the monitored one or more pressures, and determining (S7) a permeability state of the FO membrane based on a characteristic indicative of the flow.

The disclosure relates to a dialysis unit (1) with a dialysis machine (2) which has a dialysis fluid preparation device (30), a first central dialysis fluid concentrate supply device (5a) which is connected to the dialysis machine (2) via a first connecting line (9a), at least one second central dialysis fluid concentrate supply device (5b) which is connected to the dialysis machine (2) via a second connecting line (9b), and a control unit (14).When preparing the dialysis fluid for the subsequent dialysis therapy, the control unit (14) is configured to introduce a dialysis fluid concentrate or dialysis fluid concentrates not to be used in this therapy from the first dialysis fluid concentrate supply device (5a) and / or the second dialysis fluid concentrate supply device (5b) into the dialysis fluid preparation device (30) and to use them for mixing the dialysis fluid in order to flush the first connecting line (9a) and / or the second connecting line (9b), and only then to introduce a dialysis fluid concentrate to be used in the subsequent therapy into the dialysis fluid preparation device (30) and to use it for mixing the dialysis fluid. The disclosure further relates to a method for preparing a dialysis therapy and a computer program.

The invention relates to a component arrangement for a medical device comprising a first component with an outer surface, an inner surface and at least one recess extending between the outer surface and the inner surface, a second component comprising at least one screw boss with a longitudinally extended boss shaft and a bore, wherein the second component is arranged on the outer surface of the first component, the boss shaft projecting axially into the recess, and wherein an end face of the boss shaft does not project axially beyond the inner surface of the first component, and at least one screw with a screw shaft and a screw head, wherein the screw shaft is screwed into the bore and the screw head is axially supported on the inner surface of the first component, wherein the first component is subjected to compression between the screw head and the second component and the boss shaft is subjected to axial tension.which means that the first component is screwed to the second component.