2519results about "Dialysis systems" patented technology

There is provided an introducer system for percutaneously delivering a first and a second medical device to a patient. The system may comprise an introducer sheath having a longitudinal axis and a lumen formed therein. The system may also comprise a bifurcated hub coupled to a proximal end of the sheath. The hub may comprise a first arm having a first lumen and a first hemostasis valve for the passage of the first medical device. The hub may also comprise a second arm coupled to the first arm and having a second lumen and a second hemostasis valve for the passage of the second medical device. Further, the hub may comprise a connection port such that the first lumen and the second lumen are in communication with the lumen of the introducer sheath for the passage of at least one of the first and second medical devices through the introducer sheath for delivery to the patient.

The invention relates to the technical field of medical prediction, in particular to a digital twinborn prediction method for patient lung protective ventilation supported by ECMO, which comprises the following steps: extracting flow velocity change and jump points under the support of ECMO, constructing a ventilation fluctuation trend map, identifying fluctuation sections by combining compliance and pressure value ratio, delimiting lung partitions and analyzing oxygenation ratio trend. And generating an oxygenation capability classification graph, sequencing ventilation path effects, and outputting a pulmonary protective ventilation digital twinborn prediction scheme. According to the method, dynamic response mapping of ventilation behaviors is established on the basis of timing sequence changes of breathing flow velocity jump characteristics and compliance pressure value ratios, the lung regional ventilation state is accurately recognized, lung function zoning division is achieved by combining oxygenation ratio waveform classification, ventilation path utility sorting is completed through oxygenation descending characteristics under path coverage, and the lung function evaluation accuracy is improved. And a path state prediction sequence is constructed by fusing the change relationship between the tensile stress and the ventilation pressure, so that the dynamic adaptability of the ventilation strategy to the lung mechanics and oxygenation state and the region matching precision are improved.

The invention relates to the technical field of deep learning, in particular to a dialysis hypotension risk prediction system and method based on deep learning, and the system comprises a multi-point signal collection module, a signal processing module, a multi-scale causal expansion convolutional network prediction module, an osmotic pressure correction module and a dialysis plan automatic adjustment module. The method comprises the following steps: synchronously collecting physiological signals of a patient through a finger tip photoelectric volume sensor and a radial artery piezoelectric sensor array, carrying out band-pass filtering and morphological refinement processing on the signals, extracting features, and calculating pulse wave conduction time and a change rate thereof; inputting the characteristic parameters into a multi-scale causal expansion convolutional network to predict the hypotension risk in dialysis; dynamically correcting the prediction result according to electrolyte monitoring data; based on the corrected risk, a hierarchical response strategy is adopted to automatically adjust dialysis parameters, a multi-scale causal expansion convolutional network is adopted to capture physiological parameter changes on different time scales at the same time, and high-precision prediction of hypotension is achieved.

A polymer of formula I. and uses of the polymer for the removal of removing per- and polyfluoroalkyl substances from aqueous solutions.

The invention relates to the technical field of hemodialysis, and discloses a hemodialysis ultrafiltration amount adjusting system based on multi-parameter self-adaptive control, which is used for solving the problem of insufficient prediction and prevention precision of a hemodialysis induced hypotension risk in a traditional system. According to the method, firstly, multi-parameter physiological data of the blood volume, the blood pressure and the ion concentration are synchronously collected in the whole dialysis process, then a physiological state data set is constructed through unified standardization and correlation matching, related change modes of the blood volume and the blood pressure are extracted, and ion deviation is superposed to form comprehensive risk characteristics; the risk characteristics are compared with a preset threshold value through trend analysis, the weight of each risk component is adjusted in a self-adaptive mode, a hypotension risk trend index is generated, the ultrafiltration rate is dynamically adjusted in a graded mode according to the indexes, the indexes are coupled with a real-time physiological data feedback closed loop, and therefore the prediction precision and the regulation and control refinement level of dialysis-induced hypotension are improved.

The invention relates to the technical field of medical instruments, in particular to an internal fistula blood vessel detection system for hemodialysis, which comprises a data acquisition module for acquiring ultrasonic data, an impedance value, tremor intensity and a pressure spectrum; the mode determining module is used for determining a detection mode of the internal fistula blood vessel based on the tortuosity index and determining massage frequency and air bag pressure according to the blood vessel compliance index; the stenosis analysis module is used for determining whether the internal fistula blood vessel is stenosis or not based on the stenosis risk characterization parameter and determining whether the stenosis degree of the internal fistula blood vessel is in a reasonable range or not according to the blood flow velocity characterization value; the frequency adjusting module determines and adjusts the massage frequency based on the ratio; the injury analysis module is used for determining whether the internal fistula blood vessel is injured or not in the dialysis process on the basis of the bioelectrical impedance change rate and determining whether the internal fistula blood vessel injury is in a reasonable range or not after dialysis according to the tremor intensity change value; the pressure adjusting module determines and adjusts the pressure of the air bag based on the difference value. The accuracy of internal fistula blood vessel detection is improved.

The invention discloses a dialysate regeneration system and dialysis equipment, the dialysate regeneration system comprises a waste liquid passage, a slow flow box, an electromagnetic valve, a reactor and an adsorption mechanism, the waste liquid passage is in through connection with the slow flow box, the slow flow box is connected with the reactor through a pipeline, and the pipeline is provided with the electromagnetic valve. The fixing amount of a urease layer is increased through the treatment film with the three cambered surfaces, the urea decomposition efficiency is improved, the diffusion path of toxins on the treatment film is shortened, meanwhile, the treatment film with the cambered surface structure can guide dialysis waste liquid entering the reactor to generate local turbulence, and the toxins are prevented from being accumulated on the surface of the treatment film; the dialyzer is arranged, the micro horse is started to drive the hollow fiber to rotate, the material exchange efficiency of blood and dialysate is improved, and the situation that protein and cells are deposited on the surface of the hollow fiber, and the service life of the hollow fiber is shortened is avoided.

The invention relates to the technical field of medical monitoring, and discloses an intelligent monitoring device for a blood return end of hemodialysis, the device is in communication connection with a dialyzer for hemodialysis, and the device comprises an alarm trigger module, a temperature compensation module and a screen display module. According to the application, the alarm triggering module accurately monitors the blood return temperature, the blood return flow velocity and the induced blood flow velocity, captures abnormity in real time and triggers alarm; the temperature compensation module not only guarantees life safety of the patient, but also improves temperature control adaptability; the screen display module displays core parameters and trend curves in real time, space limitation is broken through, and medical workers are assisted in remote quick response; the portability of the device is realized by the micro clamping and fixing module; the clinical flexibility is enhanced through threshold adjustment; the power-on self-test further ensures the operation safety of the equipment; therefore, full-process optimization from data monitoring, intelligent control to remote monitoring is realized, and accurate, safe and personalized dialysis support is provided for patients.

The invention discloses an in-vitro pipeline and filter blood coagulation monitoring method and system, and belongs to the technical field of intelligent medical instruments, and the in-vitro pipeline and filter blood coagulation monitoring method comprises the following steps: S1, obtaining operation data and operation parameters of a corresponding hemodialysis machine and biochemical indexes of a patient corresponding to the hemodialysis machine based on a pipeline and a filter; optimizing the long-short-term memory network based on a doliolaria group optimization algorithm to obtain a monitoring model; s2, preprocessing the operation data, the operation parameters and the biochemical indexes to obtain a training set, a verification set and a real-time data set; s3, training the monitoring model based on the training set and the verification set to obtain a real-time monitoring model; s4, inputting the real-time data set into a real-time monitoring model to obtain blood coagulation grades of the pipeline and the filter; s5, the corresponding in-vitro pipeline and filter blood coagulation monitoring system executes an early warning action based on the early warning rule and the blood coagulation level; the blood coagulation level of the pipeline and the filter is monitored through the interrelation of the operation data and the operation parameters of the hemodialysis machine and the biochemical indexes of the patient, and the recognition accuracy of the blood coagulation event is remarkably improved.

The double-cavity cannula comprises a cannula body, the cannula body comprises an outer tube with an opening in the upper end and an inner tube coaxial with the outer tube, the upper end of the outer wall of the cannula body is provided with a connecting part communicated with the cannula body in a matched mode, a plurality of blood guide side holes are formed in the lower portion of the outer wall of the outer tube, and the opening in the lower end of the inner tube is communicated with a blood guide hopper. A blood return assembly is arranged on the inner wall of the outer tube and above the blood guide hopper, a blood flow guide cover is arranged on the inner wall of a blood return opening of the blood return assembly in a matched mode, a balloon capable of being filled and emptied is arranged on the outer wall of the outer tube and above the blood guide side hole, a filling valve is arranged on one side of the outer wall of the connecting part, and the filling valve is communicated with the balloon through a filling pipeline. When blood is guided, the conditions of local blood vessel wall adsorption and unsmooth blood guiding cannot be easily caused by the design of the blood guiding side holes, and the injection effect, blood turbulence and hemolysis risk increase cannot occur during blood return.

The invention provides a functional nanofiber material as well as a preparation method and application thereof, and the preparation method comprises the following steps: (1) adding raw materials into water to form an electrostatic spinning solution; performing electrostatic spinning to obtain a nanofiber membrane; (2) cross-linking the nanofiber membrane in an organic solvent under the catalysis of acid to obtain a cross-linked nanofiber membrane; and (3) carrying out grafting reaction on the cross-linked nanofiber membrane in a polyamine cross-linking agent, and then reacting with a sulfur-containing reagent to obtain the functional nanofiber material, the functionalized nanofiber material prepared by the preparation method disclosed by the invention combines good biocompatibility of polyvinyl alcohol, high specific surface area and high porosity of nanofiber and a synergistic adsorption effect of the polyamine cross-linking agent and cysteine, and has the advantages of large adsorption capacity, high adsorption rate, strong selectivity, good biocompatibility, stable structure and the like; the heavy metal ions in the plasma can be efficiently and safely removed, and a plurality of defects of the existing adsorption material are overcome.

The invention relates to the field of medical instruments, in particular to an extracorporeal membrane oxygenation device with mechanical protection, which comprises a main device and a consumable component, one side of the main device is provided with a connecting piece and a pump head driving seat, and the top of the main device is provided with a protection frame; the consumable assembly is detachably installed on the connecting piece, the consumable assembly is provided with a pump head connected with the pump head driving base, and the protection frame is suitable for forming external protection on the consumable assembly installed on the connecting piece. The oxygenator and the pump head are integrated on the consumable assembly and then installed on the connecting piece of the main equipment in a buckled and matched mode, a mechanical protection frame is formed for the consumable assembly based on the protection frame on the main equipment, the consumable assembly is not prone to being collided by machines in the transferring process, and the transferring safety is improved. The extracorporeal membrane oxygenation device is small in size, light in weight, convenient to operate, very convenient to transfer, and suitable for forming the portable and integrated extracorporeal membrane oxygenation device with mechanical protection, and the extracorporeal membrane oxygenation device is used for being transferred between long-distance hospitals.

To enable water removal control that can respond to various patients and the conditions of each patient, and that can perform efficient water removal treatment while reducing the burden on the patient. [Solution] The device has a memory unit that stores the water removal achievement rate at a specified elapsed time during blood purification treatment, and a calculation unit that sets a water removal profile in which the water removal rate gradually decreases from the start to the end of blood purification treatment, and the calculation unit is equipped with a water removal rate determination unit that determines the water removal rate for a specified time at a specified elapsed time based on the water removal achievement rate.

The invention relates to a bag (1) made of a flexible wall, which bag is fitted with an inlet fluid line for introducing dissolution water, and with an outlet fluid line (121, 122) for extracting a solution obtained. According to the invention, the inside of the bag has a lower edge (13) in the overall shape of a V, the point of the V being further away from the centre of the bag than the arms of the V, the outlet fluid line opening into the bag as close as possible to the point of the V.

A system configured to enclose a premature fetus within an extracorporeal environment to promote growth of the fetus and increase viability of the fetus, The system includes a chamber having an interior space configured to enclose the fetus, a first fluid circuit that delivers sterile fluid to the chamber, and a second fluid system that transfers oxygen to the fetus. The system chamber includes a stop mechanism including a clamp and an actuator, the clanip positioned in the interior space, the actuator coupled to the clamp such that movement of the actuator moves the clamp, and the actuator positioned at least partially outside the interior space. A method of using the system to treat hyperbilirubinemia is also provided.

To provide an estimation method of a recirculation rate enabling estimation of a recirculation rate without being limited by a preparation location of a blood marker or an arrangement location of detection means of the blood marker.SOLUTION: An estimation method of a recirculation rate includes the steps of: acquiring data representing an amount of change in blood concentration after recirculation when a blood marker is added to blood to be extracorporeally circulated, data representing a relation between an amount of change in blood concentration after recirculation and blood concentration, and data representing a relation between the amount of change in blood concentration after recirculation and a blood flow rate; creating a model by multivariate analysis or machine learning to obtain a regression equation or a conversion model, with the amount of change in blood concentration after recirculation, blood concentration and a blood flow rate used as an explanatory variables and the recirculation rate as an objective variable; acquiring data representing the amount of change in blood concentration, blood concentration and a blood flow rate of blood flowing through an arterial line or a venous line; and inputting treatment data to the regression equation or the conversion model to estimate the recirculation rate.SELECTED DRAWING: Figure 3A

The invention is applicable to the technical field of CRRT pipelines, and provides an intelligent CRRT pipeline integrated with a multi-parameter monitoring sensor, which comprises five modules, namely an artery end, a vein end, a filter unit, a waste liquid end and a displacement liquid / dialysate passage, which are connected through quick connectors; sensor arrays are integrated in the artery end, the vein end, the filter unit, the waste liquid end and the replacement liquid / dialysate access module. The CRRT pipeline can continuously and synchronously collect key physiological and treatment parameter data such as pressure, temperature, bubble existence, blood leakage, solution concentration, blood flow velocity / hematocrit / hemoglobin in the pipeline; and real-time feedback is realized through a display terminal or a remote system. According to the technical scheme, whole-process in-situ, real-time and multi-parameter integrated monitoring is achieved, the intelligent and automatic level is improved, a foundation is laid for closed-loop control, remote monitoring and big data analysis, and the burden of medical staff is relieved. According to the pipeline, the safety, the effectiveness and the intelligent degree of CRRT treatment are improved.

The hemodialysis device for the nephrology department relates to the technical field of medical instruments and comprises a body mechanism, the body mechanism comprises a dialyzer body, a dialyzer is fixedly installed on the left side face of the dialyzer body, and the outer surface of the dialyzer is fixedly communicated with a blood inlet pipe, a blood outlet pipe, a liquid inlet pipe and a liquid outlet pipe. A treatment mechanism is arranged on the left side of the dialyzer main body; the processing mechanism comprises an expansion unit, and the expansion unit is located on the left side of the dialyzer body and used for expanding the inner diameter of the blocked pipeline position; the treatment mechanism further comprises a dredging unit, the dredging unit is located on the left side of the dialyzer body, the expansion unit is used in cooperation with the dredging unit, and the dredging unit is used for dredging thrombus and other substances blocking a pipeline. Therefore, thrombus and other substances blocking the blood inlet tube can smoothly pass through, and blood dialysis of a patient is prevented from being affected by blocking of the blood inlet tube.

The present invention relates to systems and methods for optimizing plasma collection volume. A plasma withdrawal system and a method for operating a plasma withdrawal system are provided by which the volume / weight of the anticoagulated plasma collected is optimized. In one example, a nomogram is provided that utilizes the donor hematocrit to calculate the volume / weight of raw plasma within a plasma product having a maximum volume allowed by the FDA nomogram. In a plasma withdrawal process having multiple collection phases followed by a reinfusion cycle in which concentrated red blood cells are returned to the donor, the volume of plasma product to be collected is calculated prior to the start of each collection cycle to account for the increasing hematocrit of the donor, resulting in a greater total volume of plasma product to be collected during the plasma withdrawal process.

Disclosed in the present application are an HCT prediction method and system, a device, and a medium. Photons in a photon group are emitted into an extracorporeal circulation blood model so that the photons are reflected, scattered, or absorbed during movement. The extracorporeal circulation blood model is a model constructed on the basis of the thickness of an extracorporeal circulation tube, the thickness of the blood, and the distance from a light source generator to a detector. Light intensity data corresponding to photons reaching the detector are acquired. The acquired light intensity data are input into a prediction model to obtain a hematocrit (HCT) prediction value. The prediction model is a model constructed on the basis of a BP neural network and the relationship between light intensity and HCT. The prediction model combining simulation and neural network increases the data volume, achieves continuous non-invasive estimation of HCT by means of algorithm model optimization, and improves the accuracy of HCT prediction.

The invention relates to the technical field of medical equipment, in particular to an edge calculation respirator system and method for adaptive ventilation control, and the system comprises a respirator end which is provided with an edge calculation module and a local control model; the edge calculation module is used for collecting multi-modal physiological parameters of a patient and performing data preprocessing on the multi-modal physiological parameters of the patient to generate a multi-dimensional feature vector; the local control model carries out real-time self-adaptive adjustment on ventilation parameters of the breathing machine based on the multi-modal physiological parameters of the patient and the baseline characteristics of the patient; the cloud server is in communication connection with the respirator end and is configured with a global optimization model; and the cloud server receives historical ventilation data of the respirator end, and the global optimization model performs training based on the historical ventilation data to generate a personalized ventilation strategy, and issues the personalized ventilation strategy to the respirator end for correcting adjustment of the local control model. According to the invention, low latency and high reliability of bedside control are guaranteed through a side cloud collaborative architecture.

The present invention refers to a system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, the invention refers to a container and blood treatment device to be used in a method according to the present invention.

The invention relates to the technical field of medical monitoring, in particular to a patient cardiopulmonary function monitoring system and method and a computer readable storage medium, the monitoring system comprises a breathing machine, a pulmonary membrane oxygenation device, a first monitoring module and a second monitoring module, and the breathing machine comprises a breathing circuit, a processing module and a display module; the pulmonary membrane oxygenation equipment comprises an oxygenator; the first monitoring module is used for monitoring carbon dioxide exhaling parameters in gas exhaled by a patient in real time; the second monitoring module is used for monitoring carbon dioxide discharge parameters in gas discharged by the oxygenator in real time. By means of real-time monitoring of exhaling parameters of carbon dioxide in gas exhaled by a patient and discharging parameters of carbon dioxide in gas discharged by an oxygenator, continuous monitoring of the change condition of the cardiac function and / or the lung function of the patient is achieved, oxygen consumption of the patient can be truly reflected, parameter adjustment of a breathing machine and lung membrane oxygenation equipment is facilitated, and the patient experience is improved. And guidance is provided for turning of the pulmonary membrane oxygenation equipment.

The invention discloses a medicine adding device used in cooperation with a hemodialysis machine and a using method of the medicine adding device. The medicine adding device used in cooperation with the hemodialysis machine comprises a blood pipeline and a medicine adding device, the first medicine adding assembly comprises a bin body, a first medicine liquid guide pipe and a flow control assembly. During use, medicine entering the bin body can be slowly injected into the blood pipeline through the first medicine liquid guide pipe by adjusting the flow control assembly. Under an original conventional medicine adding mode, medicine injected into blood at a time through an injector can be slowly injected into the blood when the first medicine adding assembly of the medicine adding device is adopted for medicine adding, so that the medicine can flow into the blood slowly and more dispersedly, is more fully and uniformly mixed with the blood and then flows back into the body of a patient along with the blood successively, and the medicine adding effect is good. A better treatment effect is achieved; and meanwhile, for the medicament needing to be slowly injected, medical personnel do not need to slowly push the piston of the injector to slowly move to inject the medicament, so that the operation difficulty of slowly injecting the medicament is reduced.

The invention relates to the technical field of medical equipment, and discloses an intelligent temperature control and flow control system for hemodialysis, which comprises a dialysis pipeline shunting shell; the two main pipelines are arranged in the dialysis pipeline shunting shell, and a plurality of slave pipelines are arranged between the two main pipelines; when the flow rate of the liquid is low, the slave pipeline is far away from the heating component, the temperature of the liquid cannot rise too fast under the condition that the flow rate is low, the knob part can move to the slave pipeline when controlling the valve component to increase the flow rate of the liquid, and the slave pipeline moves close to the heating component. The distance between the auxiliary pipeline and the temperature rising component is reduced, when the flow rate of liquid with large flow is high, the auxiliary pipeline gets close to the temperature rising component, heat generated by the temperature rising component can be better received by the auxiliary pipeline and conducted to the liquid, and the flow adjusting system and the temperature control system can cooperate to achieve the purpose that the flow adjusting system and the temperature control system work together. A preset temperature value can be provided for the dialysis liquid all the time when the flow is increased or decreased.

The present invention refers to a system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, the invention refers to a container and blood treatment device to be used in a method according to the present invention.

The invention relates to the crossing field of computer technology and edge calculation, and discloses a blood purification equipment real-time control method based on edge calculation. According to the method, multi-modal real-time physiological parameters, historical dialysis data and a current treatment target are fused through a local edge calculation unit, an individualized body fluid dynamic response prediction model is constructed, and an ultrafiltration rate instruction is optimized and generated within a millisecond level; the system comprises a multi-mode sensor array, a historical data storage module, a task planning interface, an edge computing unit and an ultrafiltration pump controller. According to the application, the hemodynamic state is accurately maintained, the risk of hypotension is remarkably reduced, and the treatment safety and individualization level are improved.

The invention relates to the technical field of biomedical engineering, in particular to a household noninvasive anemia monitoring and early warning method and system in a chronic kidney disease scene. The system comprises hemoglobin detection equipment, a dialysis machine and processing equipment, physiological data of the chronic kidney disease are collected through the hemoglobin detection equipment, dialysis is conducted on the chronic kidney disease through the dialysis machine, and dialysis data are recorded; and determining a predicted anemia risk grade of the chronic kidney patient through the processing equipment according to the physiological data, the dialysis data and the physical sign data of the chronic kidney patient, and performing anemia early warning according to the predicted anemia risk grade and the physiological data. According to the application, anemia home monitoring of the chronic kidney disease patient is realized, the patient does not need to go back to a hospital regularly, the economic burden and the body burden of the chronic kidney disease patient are reduced, and the life quality of the chronic kidney disease patient is remarkably improved.

To enable water removal control that can respond to various patients and the conditions of each patient, and that can perform efficient water removal treatment while reducing the burden on the patient. [Solution] The device has a memory unit that stores the water removal achievement rate during a specified elapsed time in the first half of the treatment time of blood purification treatment, and a calculation unit that sets a water removal profile in which the water removal rate gradually decreases from the start to the end of blood purification treatment, and the calculation unit is equipped with a water removal rate determination unit that determines the water removal rate for a specified time during the specified elapsed time based on the water removal achievement rate.

The present invention discloses a hemodialysis fluid balance control method, device, electronic device, and medium, relating to the technical field of intelligent regulation. The hemodialysis fluid balance control method includes: in response to a patient experiencing a hypotensive event, determining whether the hypotensive event is caused by a hypoglycemic event; if the hypotensive event is caused by a hypoglycemic event, switching the patient's dialysate from a sugar-free dialysate to a sugar-containing dialysate; monitoring the patient's real-time blood glucose concentration; and controlling the dialysate flow rate during the patient's dialysis based on the real-time blood glucose concentration. The embodiments of the present application achieve the goal of reducing interference with hemodialysis while ensuring compensation for hypoglycemia.