48 results about "Acute stroke" patented technology

Methods for treating total and partial occlusions employ a perfusion conduit which is penetrated through the occlusive material. Oxygenated blood or other medium is then perfused through the conduit to maintain oxygenation and relieve ischemia in tissue distal to the occlusion. Optionally, the occlusion may be treated while perfusion is maintained, typically by introducing a thrombolytic or other agent into the occlusive material using the perfusion conduit. Such methods are particularly suitable for treating acute stroke to prevent irreversible damage to the cerebral tissue.

Stimulation of the facial nerve system (e.g., electrically, electromagnetically, etc.) in ischemic stroke patients will cause dilation of occluded arteries and dilation of surrounding arteries, allowing for blood flow to circumvent the obstruction and reach previously-deprived tissue. The device approaches the facial nerve and its branches in the vicinity of the ear. In use, the device can be inserted into the ear canal and/or placed in proximity to the ear in order to stimulate the facial nerve system non-invasively (e.g., using an electromagnetic field). The device can be used in the emergency treatment of acute stroke or chronically variations for long-term maintenance of blood flow to the brain and stroke prevention. Additional embodiments of the device may be adapted for use on different regions of the body.

Apparatus for helmeting with carotid collars works in conjunction with a transcranial Doppler, phased array photoacoustic device to transmit a first energy to a region of interest at an internal site of a subject to produce an image and blood flow velocities of a region of interest by outputting an optical excitation energy to said region of interest and heating said region, causing a transient thermoelastic expansion and produce a wideband ultrasonic emission. Systems integrate and register the signals for use in, for example, acute stroke care.

The invention provides a method and system for introducing cool fluid to a targeted treatment site, such as, for example, a stroke-affected brain hemisphere. In one approach, the method generally includes introducing a catheter into a branch artery of the external carotid artery, and introducing fluid into the ipsilateral internal carotid artery. In one approach, a balloon is used to occlude the external carotid artery during introduction of the fluid into the internal carotid artery.

Stimulation of the facial nerve system (e.g., electrically, electromagnetically, etc.) in stroke patients will cause dilation of occluded arteries and dilation of surrounding arteries, allowing for blood flow to circumvent the obstruction and reach previously-deprived tissue. The device approaches the facial nerve and its branches in the vicinity of the ear. In use, the device can be inserted into the ear canal or placed in proximity to the ear in order to stimulate the facial nerve system without puncturing the tympanic membrane (e.g., using an electromagnetic field). The device can also be advanced into the middle ear through a puncture created in the tympanic membrane. Branches of the facial nerve in the middle ear can then be stimulated directly (e.g., by application of electrical current). The device can be used in the emergency treatment of acute stroke or as chronically-implanted/inserted variations for long-term maintenance of blood flow to the brain and stroke prevention

A dual modality CT/MRI integrated system for the diagnosis of acute strokes and treating a patient and methods thereof. The method includes: immobilizing a patient or a portion thereof to a support; accommodating the patient or portion thereof in a CT device; scanning the same; placing the patient or portion thereof within an MRI device and imaging the same such that the orientation of the patient or portion thereof in the CT scanning and the MRI imaging is identical or at least spatially (2D or 3D) retrievable.

It has now been discovered that GLP-1 treatment after acute stroke or hemorrhage, preferably intravenous administration, can be an ideal treatment because it provides a means for optimizing insulin secretion, increasing brain anabolism, enhancing insulin effectiveness by suppressing glucagon, and maintaining euglycemia or mild hypoglycemia with no risk of severe hypoglycemia.

The current invention provides a method of identifying a ischemic lesion. The method includes loading perfusion imaging data into an electronic memory element and deriving perfusion maps from the perfusion imaging data, where the perfusion maps include a cerebral blood volume (CBV) map and an arterial delay time (DT) map, which utilize arterial delay and dispersion effects. Ischemic pixels are determined from the perfusion imaging data, where the DT is greater than a predetermined first threshold value and the CBV is below a second threshold value and the infarct portion of the ischemic lesion is determined, where DT is greater than a predetermined third threshold value and/or the CBV is below a forth threshold value. A cluster analysis is applied to all of the determined ischemic lesion and infarct pixels and the penumbra is then determined, where mismatch regions between the ischemic lesion and the infarct core define the penumbra.

The invention discloses a traditional Chinese medicine composition for treating acute stroke and a preparation method thereof. The traditional Chinese medicine composition mainly comprises the following raw medicines: senna leaf, giant knotweed rhizome, artificial bovine calculus powder, concretio silicea bambusae and trichosanthes fruit seed. The traditional Chinese medicine composition provided by the invention has the efficacy of dredging intestines and inducing resuscitation, is suitable for the symptoms of viscera and phlegm retention and viscera qi obstruction caused by the acute stroke, and is used for treating phlegm retention and viscera qi obstruction of yang and yin shutting syndromes of viscera caused by the stroke. The traditional Chinese medicine composition for treating patients suffering from acute stroke can improve clinical curative effect, reduce mortality and improve the life quality of patients; and the clinical application is safe without side effects.

The present invention relates to an in vitro method for the diagnosis and treatment guidance of a bacterial infection in patients suffering from an acute ischemic or hemorrhagic stroke, comprising the determination of the level of Procalcitonin (PCT) or a fragment thereof having at least 12 amino acid residues in a sample of a bodily fluid from said patient and the correlation of the determined level to the diagnosis of a bacterial infection in said patient.

The present invention relates to the use of G-CSF and derivatives thereof for extending the therapeutic window of subsequent thrombolytic treatment of acute stroke, and thereby, allowing the diagnostic examinations which are necessary prior to the thrombolytic treatment in order to avoid hemorrhagic and other severe adverse side effects of the thrombolysis.

The invention provides a method for enhancing the delivery of an anti-platelet drug for the treatment of acute stroke, comprising delivering a composition comprising an anti-platelet drug and a vehicle that can reduce the binding rate of plasma proteins, so that the anti-platelet drug can achieve the effect of treating acute stroke at a low dose. By use of the neuro-protective efficacy of anti-platelet drug, the invention allows the drug to release slowly to the site of treatment by combining anti-platelet drugs with a vehicle that can reduce the binding rate of plasma proteins to effectively reduce the dose of the anti-platelet drug and consequently reduce the side effects such as hypotension caused by, administration of a high dose of the anti-platelet drugs. The invention also provides a pharmaceutical composition for enhancing treatment of acute stroke and a method for treating acute stroke using the pharmaceutical composition of the invention.

The invention discloses a balloon catheter for partially blocking blood flow. The balloon catheter comprises a catheter seat and a catheter body mounted at the catheter seat, wherein a plurality of balloons are arranged on a far-end segment of the catheter body, a main hole channel and a plurality of side hole channels are formed in the catheter body, the main hole channel axially extends, and theside hole channels are isolated from another; and a main pipe and a plurality of side pipes are correspondingly arranged on the catheter seat, and the multiple side hole channels respectively communicate to different balloons and are used for respectively controlling inflation states of the multiple balloons. By inflating the multiple balloons, near-end blood vessels of a thrombus are effectivelysealed, blocked and protected to different degrees, so that early perfusion of a lot of blood flow is reduced after acute stroke is dredged, and reperfusion injury complications are reduced; by adjusting the inflation states of the multiple balloons, multi-level accurate adjustment of the sealing states of blood vessels is realized, so that accurate control of perfusion blood flow is realized, and functional recovery of the brain is promoted; and manifold auxiliary instruments do not need to be used, and blood flow retardant radiography evaluation, short-term pipe flushing and liquid perfusion during operations can be realized by virtue of the single instrument.

The invention discloses a stroke treatment network system and a stroke treatment platform. A stroke treatment platform is constructed, the information expressway for acute stroke treatment is built before the hospital, so that seamless joint of pre-hospital first aid and in-hospital first aid, no arrival of a patient and first arrival of information are achieved, delay in the stroke hospital is reduced, acute stroke treatment time is gained, and thus the treatment efficiency of the acute stroke patient is improved. A three-in-one cerebral stroke treatment network integrating pre-hospital first aid, in-hospital diagnosis and treatment and post-hospital follow-up visit is built based on the stroke treatment platform, so that the pre-hospital stroke treatment process is standardized and unblocked, the treatment time is shortened, the treatment efficiency is improved, and the fatality rate and disability rate of stroke attack are practically reduced.

According to the present invention, accurate T2* and vascular images are concurrently acquired by acquiring a T2* image without a flow compensation and a T2* image with a flow compensation and subtracting the two images to reconstitute an image showing the flow phenomenon. Furthermore, an accurate T2* image can be acquired by using the readout gradient without the flow compensation and also the accurate T2* and vascular images can be concurrently acquired. The clinical judgment for blood flow rate of the blood vessel and the clinical judgment for acute stroke can be concurrently made, and so the present invention can be widely utilized in clinical practice.